SIMILAR PATTERNS OF AMINO ACIDS FOR 5M24_A_9CRA501
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a8s | CHLOROPEROXIDASE F (Pseudomonasfluorescens) |
PF00561(Abhydrolase_1) | 5 | ALA A 115LEU A 117ILE A 118LEU A 76ILE A 104 | None | 1.05A | 5m24A-1a8sA:undetectable | 5m24A-1a8sA:22.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1exx | RETINOIC ACIDRECEPTOR GAMMA-2 (Homo sapiens) |
PF00104(Hormone_recep) | 12 | TRP A 227PHE A 230ALA A 234LEU A 271MET A 272ILE A 275ARG A 278SER A 289PHE A 304GLY A 393LEU A 400ILE A 412 | None961 A 450 (-3.9A)961 A 450 (-3.1A)961 A 450 (-3.6A)961 A 450 (-3.1A)961 A 450 (-3.5A)961 A 450 (-3.6A)961 A 450 (-2.5A)961 A 450 (-3.6A)961 A 450 ( 4.0A)None961 A 450 ( 4.1A) | 0.50A | 5m24A-1exxA:41.0 | 5m24A-1exxA:99.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3e | TYROSYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00579(tRNA-synt_1b) | 5 | ALA A 299ILE A 115ARG A 63GLY A 242LEU A 254 | None | 1.12A | 5m24A-1h3eA:undetectable | 5m24A-1h3eA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 5 | PHE A 220ALA A 337SER A 287GLY A 274LEU A 238 | None | 0.85A | 5m24A-1kh2A:0.0 | 5m24A-1kh2A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 5 | PHE A 220ALA A 337SER A 287GLY A 275LEU A 238 | None | 0.94A | 5m24A-1kh2A:0.0 | 5m24A-1kh2A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1krm | ADENOSINE DEAMINASE (Bos taurus) |
PF00962(A_deaminase) | 5 | PHE A 331ALA A 176GLY A 234LEU A 11ILE A 148 | None | 0.99A | 5m24A-1krmA:undetectable | 5m24A-1krmA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kya | LACCASE (Trametesversicolor) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | ALA A 6LEU A 8ILE A 49GLY A 29ILE A 2 | None | 0.91A | 5m24A-1kyaA:undetectable | 5m24A-1kyaA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH) | 5 | PHE A 12ALA A 370ILE A 336GLY A 312ILE A 378 | None | 1.00A | 5m24A-1lrtA:undetectable | 5m24A-1lrtA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v8b | ADENOSYLHOMOCYSTEINASE (Plasmodiumfalciparum) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | PHE A 405ALA A 442LEU A 446ARG A 33PHE A 401 | None | 0.78A | 5m24A-1v8bA:0.0 | 5m24A-1v8bA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x94 | PUTATIVEPHOSPHOHEPTOSEISOMERASE (Vibrio cholerae) |
PF13580(SIS_2) | 5 | ALA A 33ILE A 186PHE A 62LEU A 118ILE A 160 | None | 1.00A | 5m24A-1x94A:0.1 | 5m24A-1x94A:21.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xap | RETINOIC ACIDRECEPTOR BETA (Homo sapiens) |
PF00104(Hormone_recep) | 11 | TRP A 218PHE A 221ALA A 225LEU A 262ILE A 266ARG A 269SER A 280PHE A 295GLY A 384LEU A 391ILE A 403 | NoneTTB A 1 (-4.7A)TTB A 1 (-4.0A)TTB A 1 (-3.9A)TTB A 1 ( 4.0A)TTB A 1 (-3.3A)TTB A 1 (-3.1A)TTB A 1 ( 4.1A)TTB A 1 ( 4.0A)NoneTTB A 1 ( 4.8A) | 0.74A | 5m24A-1xapA:38.4 | 5m24A-1xapA:86.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xdk | RETINOIC ACIDRECEPTOR, BETA (Mus musculus) |
PF00104(Hormone_recep) | 11 | TRP B 218PHE B 221ALA B 225LEU B 262ILE B 266ARG B 269SER B 280PHE B 295GLY B 384LEU B 391ILE B 403 | None9CR B 600 ( 4.7A)9CR B 600 (-3.8A)9CR B 600 (-3.9A)9CR B 600 ( 3.8A)9CR B 600 (-3.8A)9CR B 600 (-3.0A)9CR B 600 (-3.9A)9CR B 600 ( 4.6A)None9CR B 600 ( 4.4A) | 0.49A | 5m24A-1xdkB:37.5 | 5m24A-1xdkB:79.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xeu | INTERNALIN C (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 5 | PHE A 80ALA A 55PHE A 96GLY A 92ILE A 87 | None | 0.94A | 5m24A-1xeuA:undetectable | 5m24A-1xeuA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y80 | PREDICTED COBALAMINBINDING PROTEIN (Moorellathermoacetica) |
PF02310(B12-binding) | 5 | MET A 156ILE A 160GLY A 177LEU A 204ILE A 142 | NoneNoneB1M A 301 (-3.5A)NoneNone | 1.10A | 5m24A-1y80A:undetectable | 5m24A-1y80A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygu | LEUKOCYTE COMMONANTIGEN (Homo sapiens) |
PF00102(Y_phosphatase) | 5 | ALA A1156LEU A1179GLY A1147LEU A1036ILE A1153 | None | 1.09A | 5m24A-1yguA:undetectable | 5m24A-1yguA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ysj | PROTEIN YXEP (Bacillussubtilis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | PHE A 127ALA A 111SER A 365GLY A 61ILE A 43 | None | 1.12A | 5m24A-1ysjA:undetectable | 5m24A-1ysjA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9v | GMP SYNTHASE (Thermoplasmaacidophilum) |
PF00117(GATase) | 5 | PHE A 154ALA A 83ILE A 161PHE A 140GLY A 91 | None | 1.05A | 5m24A-2a9vA:undetectable | 5m24A-2a9vA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fxv | XANTHINEPHOSPHORIBOSYLTRANSFERASE (Bacillussubtilis) |
PF00156(Pribosyltran) | 5 | ALA A 176ILE A 152SER A 157GLY A 39LEU A 34 | None | 1.11A | 5m24A-2fxvA:undetectable | 5m24A-2fxvA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gnw | NON-SYMBIOTICHEMOGLOBIN 1 (Oryza sativa) |
PF00042(Globin) | 5 | TRP A 40PHE A 39ALA A 124ILE A 129PHE A 78 | None | 1.07A | 5m24A-2gnwA:undetectable | 5m24A-2gnwA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hzh | LACCASE (Trametesochracea) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | ALA A 6LEU A 8ILE A 49GLY A 29ILE A 2 | None | 0.91A | 5m24A-2hzhA:undetectable | 5m24A-2hzhA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m5j | HASR PROTEIN (Serratiamarcescens) |
PF07660(STN) | 5 | ALA A 26MET A 48GLY A 68LEU A 63ILE A 18 | None | 1.08A | 5m24A-2m5jA:undetectable | 5m24A-2m5jA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmp | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Arabidopsisthaliana) |
PF02542(YgbB) | 5 | ALA A 83LEU A 52ILE A 60GLY A 7LEU A 97 | NoneNoneC5P A 700 (-4.9A)NoneNone | 1.06A | 5m24A-2pmpA:undetectable | 5m24A-2pmpA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qq8 | TBC1 DOMAIN FAMILYMEMBER 14 (Homo sapiens) |
PF00566(RabGAP-TBC) | 5 | ALA A 514LEU A 506ILE A 503LEU A 575ILE A 400 | NoneUNX A 201 ( 4.0A)NoneNoneNone | 0.99A | 5m24A-2qq8A:undetectable | 5m24A-2qq8A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r6r | CELL DIVISIONPROTEIN FTSZ (Aquifexaeolicus) |
PF00091(Tubulin)PF12327(FtsZ_C) | 6 | PHE 1 132ALA 1 178ILE 1 165SER 1 169GLY 1 18ILE 1 175 | NoneNoneNoneNoneGDP 1 339 (-3.4A)None | 1.33A | 5m24A-2r6r1:undetectable | 5m24A-2r6r1:24.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vc2 | INTEGRIN ALPHA-IIB (Homo sapiens) |
PF01839(FG-GAP)PF13517(VCBS) | 5 | LEU A 306SER A 344PHE A 289GLY A 256ILE A 360 | None | 1.08A | 5m24A-2vc2A:undetectable | 5m24A-2vc2A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vun | ENAMIDASE (Eubacteriumbarkeri) |
PF01979(Amidohydro_1) | 5 | ALA A 36LEU A 42MET A 43LEU A 333ILE A 37 | None | 1.12A | 5m24A-2vunA:undetectable | 5m24A-2vunA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2woc | ADP-RIBOSYL-[DINITROGEN REDUCTASE]GLYCOHYDROLASE (Rhodospirillumrubrum) |
PF03747(ADP_ribosyl_GH) | 5 | ALA A 129LEU A 250SER A 65LEU A 193ILE A 213 | None | 1.10A | 5m24A-2wocA:undetectable | 5m24A-2wocA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wpg | AMYLOSUCRASE ORALPHA AMYLASE (Xanthomonascampestris) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 5 | ALA A 484ILE A 373PHE A 575GLY A 357LEU A 477 | None | 1.04A | 5m24A-2wpgA:undetectable | 5m24A-2wpgA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xyb | LACCASE (Trametescinnabarina) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | ALA A 6LEU A 8ILE A 49GLY A 29ILE A 2 | None | 0.94A | 5m24A-2xybA:undetectable | 5m24A-2xybA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a68 | FERRITIN-4,CHLOROPLASTIC (Glycine max) |
PF00210(Ferritin) | 5 | PHE A 84ALA A 132ILE A 181SER A 138PHE A 83 | None | 1.02A | 5m24A-3a68A:undetectable | 5m24A-3a68A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ab7 | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA0350 (Thermusthermophilus) |
PF00582(Usp) | 5 | ALA A 6LEU A 4ILE A 3LEU A 137ILE A 103 | ALA A 6 ( 0.0A)LEU A 4 ( 0.6A)ILE A 3 ( 0.7A)LEU A 137 ( 0.6A)ILE A 103 ( 0.7A) | 1.05A | 5m24A-3ab7A:undetectable | 5m24A-3ab7A:24.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bj5 | PROTEINDISULFIDE-ISOMERASE (Homo sapiens) |
PF13848(Thioredoxin_6) | 5 | ALA A 272ILE A 301PHE A 232GLY A 234ILE A 221 | None | 1.05A | 5m24A-3bj5A:undetectable | 5m24A-3bj5A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE EPSILON SUBUNIT (Methanosarcinabarkeri) |
PF02552(CO_dh) | 5 | ALA G 66LEU G 38ILE G 112SER G 58ILE G 85 | None | 1.08A | 5m24A-3cf4G:undetectable | 5m24A-3cf4G:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkt | MARITIMACIN (Thermotogamaritima) |
PF04454(Linocin_M18) | 5 | ALA A 154LEU A 266PHE A 183LEU A 193ILE A 155 | None | 1.09A | 5m24A-3dktA:undetectable | 5m24A-3dktA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dlc | PUTATIVES-ADENOSYL-L-METHIONINE-DEPENDENTMETHYLTRANSFERASE (Methanococcusmaripaludis) |
PF08241(Methyltransf_11) | 5 | ALA A 59ILE A 35SER A 64GLY A 148LEU A 154 | None | 1.06A | 5m24A-3dlcA:undetectable | 5m24A-3dlcA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dp9 | MTA/SAH NUCLEOSIDASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 5 | ALA A 55MET A 9ILE A 50GLY A 75ILE A 179 | NoneBIG A 301 ( 4.1A)BIG A 301 (-3.8A)NoneNone | 1.10A | 5m24A-3dp9A:undetectable | 5m24A-3dp9A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eeq | PUTATIVE COBALAMINBIOSYNTHESIS PROTEING HOMOLOG (Sulfolobussolfataricus) |
PF01890(CbiG_C)PF11760(CbiG_N) | 5 | ALA A 330LEU A 316ILE A 317SER A 217GLY A 16 | None | 1.08A | 5m24A-3eeqA:undetectable | 5m24A-3eeqA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzd | SELENOCYSTEINE LYASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU C 195MET C 194ILE C 193SER C 210GLY C 201 | None | 1.05A | 5m24A-3gzdC:undetectable | 5m24A-3gzdC:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHA (Moorellathermoacetica) |
PF03598(CdhC) | 5 | PHE M 251ALA M 305ILE M 311PHE M 181ILE M 301 | None | 1.01A | 5m24A-3i04M:undetectable | 5m24A-3i04M:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kw3 | ALANINE RACEMASE (Bartonellahenselae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | ALA A 252ILE A 339GLY A 299LEU A 308ILE A 283 | None | 1.05A | 5m24A-3kw3A:undetectable | 5m24A-3kw3A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4v | MTA/SAH NUCLEOSIDASE (Escherichiacoli) |
PF01048(PNP_UDP_1) | 5 | ALA A 55MET A 9ILE A 50GLY A 75ILE A 178 | None4CT A 233 ( 3.8A)4CT A 233 (-3.7A)NoneNone | 1.12A | 5m24A-3o4vA:undetectable | 5m24A-3o4vA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olm | E3 UBIQUITIN-PROTEINLIGASE RSP5 (Saccharomycescerevisiae) |
PF00397(WW)PF00632(HECT) | 5 | ALA A 468LEU A 507GLY A 555LEU A 480ILE A 457 | None | 1.07A | 5m24A-3olmA:undetectable | 5m24A-3olmA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbp | NUCLEOPORINNUP116/NSP116 (Saccharomycescerevisiae) |
PF04096(Nucleoporin2) | 5 | PHE B1005ALA B1109GLY B 996LEU B1019ILE B1033 | None | 1.03A | 5m24A-3pbpB:undetectable | 5m24A-3pbpB:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qka | ENOYL-COA HYDRATASE,ECHA5 (Mycobacteriummarinum) |
PF00378(ECH_1) | 5 | TRP A 114PHE A 39ALA A 51GLY A 55LEU A 111 | None | 1.13A | 5m24A-3qkaA:undetectable | 5m24A-3qkaA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0z | D-SERINE DEHYDRATASE (Salmonellaenterica) |
PF00291(PALP) | 5 | PHE A 65ILE A 175SER A 112GLY A 181LEU A 148 | None | 1.09A | 5m24A-3r0zA:undetectable | 5m24A-3r0zA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3c | 4-HYDROXYBENZOYL-COATHIOESTERASE (Arthrobactersp.) |
PF03061(4HBT) | 5 | ALA A 111LEU A 75MET A 74SER A 140GLY A 13 | NoneNone4CO A 152 (-4.2A)NoneNone | 1.10A | 5m24A-3r3cA:undetectable | 5m24A-3r3cA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r6h | ENOYL-COA HYDRATASE,ECHA3 (Mycobacteriummarinum) |
PF00378(ECH_1) | 5 | PHE A 174ALA A 109MET A 142SER A 114GLY A 159 | None | 0.85A | 5m24A-3r6hA:undetectable | 5m24A-3r6hA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9q | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | TRP A 118PHE A 43ALA A 55GLY A 59LEU A 115 | None | 1.09A | 5m24A-3r9qA:undetectable | 5m24A-3r9qA:25.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s8i | PROTEIN DDI1 HOMOLOG1 (Homo sapiens) |
PF09668(Asp_protease) | 5 | PHE A 318ALA A 305LEU A 281MET A 279LEU A 255 | None | 1.05A | 5m24A-3s8iA:undetectable | 5m24A-3s8iA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t0p | DNA POLYMERASE III,BETA SUBUNIT ([Eubacterium]rectale) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | ILE A 16SER A 18PHE A 227GLY A 208LEU A 134 | None | 1.06A | 5m24A-3t0pA:undetectable | 5m24A-3t0pA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u2h | S-LAYER PROTEINMA0829 (Methanosarcinaacetivorans) |
PF07752(S-layer) | 5 | LEU A 525ILE A 527SER A 508PHE A 376ILE A 391 | None | 1.07A | 5m24A-3u2hA:undetectable | 5m24A-3u2hA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3up4 | OTEMO (Pseudomonasputida) |
PF00743(FMO-like) | 5 | TRP A 170PHE A 183ALA A 204LEU A 211ILE A 200 | None | 1.10A | 5m24A-3up4A:undetectable | 5m24A-3up4A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayj | BOGT -METAL-INDEPENDENTGLYCOSYLTRANSFERASE (Bacteroidesovatus) |
PF03414(Glyco_transf_6) | 5 | PHE A 28ILE A 226SER A 102PHE A 94GLY A 160 | None | 1.07A | 5m24A-4ayjA:undetectable | 5m24A-4ayjA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0z | 26S PROTEASOMEREGULATORY SUBUNITRPN12 (Schizosaccharomycespombe) |
PF10075(CSN8_PSD8_EIF3K) | 5 | ALA A 74ILE A 62SER A 69GLY A 92ILE A 78 | NoneSGM A1226 (-4.7A)NoneNoneNone | 1.12A | 5m24A-4b0zA:undetectable | 5m24A-4b0zA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cak | INTEGRIN ALPHA-IIB (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 5 | LEU A 306SER A 344PHE A 289GLY A 256ILE A 360 | None | 1.10A | 5m24A-4cakA:undetectable | 5m24A-4cakA:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecg | PUTATIVEIRON-REGULATEDPROTEIN A (Parabacteroidesdistasonis) |
PF09375(Peptidase_M75) | 5 | ALA A 115PHE A 61GLY A 323LEU A 337ILE A 317 | None | 1.00A | 5m24A-4ecgA:undetectable | 5m24A-4ecgA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecg | PUTATIVEIRON-REGULATEDPROTEIN A (Parabacteroidesdistasonis) |
PF09375(Peptidase_M75) | 5 | ALA A 115PHE A 61GLY A 324LEU A 337ILE A 317 | None | 1.06A | 5m24A-4ecgA:undetectable | 5m24A-4ecgA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ehi | BIFUNCTIONAL PURINEBIOSYNTHESIS PROTEINPURH (Campylobacterjejuni) |
PF01808(AICARFT_IMPCHas)PF02142(MGS) | 5 | PHE A 231LEU A 350ILE A 351PHE A 226ILE A 246 | None | 1.13A | 5m24A-4ehiA:undetectable | 5m24A-4ehiA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ewc | PUTATIVENUCLEOPROTEIN (Salmon isavirus) |
no annotation | 5 | LEU A 390ILE A 394GLY A 170LEU A 177ILE A 257 | None | 0.92A | 5m24A-4ewcA:undetectable | 5m24A-4ewcA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3p | GLUTAMINE-BINDINGPERIPLASMIC PROTEIN (Burkholderiapseudomallei) |
PF00497(SBP_bac_3) | 5 | TRP A 64ILE A 68GLY A 211LEU A 218ILE A 58 | None | 1.11A | 5m24A-4f3pA:undetectable | 5m24A-4f3pA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbl | LIPS LIPOLYTICENZYME (unidentified) |
PF12146(Hydrolase_4) | 5 | ALA A 219MET A 122GLY A 128LEU A 153ILE A 221 | None | 0.98A | 5m24A-4fblA:undetectable | 5m24A-4fblA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hi4 | AEROTAXIS TRANSDUCERAER2 (Pseudomonasaeruginosa) |
PF13188(PAS_8) | 5 | PHE A 233LEU A 206ILE A 213GLY A 223ILE A 195 | HEM A 301 (-2.8A)NoneNoneNoneHEM A 301 (-4.5A) | 1.13A | 5m24A-4hi4A:undetectable | 5m24A-4hi4A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hou | INTERFERON-INDUCEDPROTEIN WITHTETRATRICOPEPTIDEREPEATS 1 (Homo sapiens) |
PF13181(TPR_8)PF13424(TPR_12) | 5 | TRP A 147ALA A 182LEU A 206GLY A 217ILE A 183 | None | 1.09A | 5m24A-4houA:undetectable | 5m24A-4houA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hy3 | PHOSPHOGLYCERATEOXIDOREDUCTASE (Rhizobium etli) |
PF02826(2-Hacid_dh_C) | 5 | ALA A 12ILE A 36ARG A 27LEU A 75ILE A 44 | None | 1.12A | 5m24A-4hy3A:undetectable | 5m24A-4hy3A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ip3 | ORF169B (Shigellaflexneri) |
no annotation | 6 | ALA A 143MET A 137ILE A 190SER A 104PHE A 94GLY A 64 | None | 1.36A | 5m24A-4ip3A:undetectable | 5m24A-4ip3A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jgj | CARCINOEMBRYONICANTIGEN-RELATED CELLADHESION MOLECULE 15 (Mus musculus) |
PF07686(V-set) | 5 | ALA A 74LEU A 85GLY A 91LEU A 103ILE A 95 | None | 1.05A | 5m24A-4jgjA:undetectable | 5m24A-4jgjA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4krf | PROTEIN ARGONAUTE-1 (Homo sapiens) |
PF02170(PAZ)PF02171(Piwi)PF08699(ArgoL1)PF16486(ArgoN)PF16487(ArgoMid)PF16488(ArgoL2) | 5 | ALA A 688LEU A 648ILE A 649GLY A 614ILE A 685 | None | 1.07A | 5m24A-4krfA:undetectable | 5m24A-4krfA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5i | TRANSCRIPTIONALREGULATOR LSRR (Escherichiacoli) |
PF04198(Sugar-bind) | 5 | LEU A 132ILE A 160GLY A 125LEU A 245ILE A 207 | None | 1.11A | 5m24A-4l5iA:undetectable | 5m24A-4l5iA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n2z | GH62ARABINOFURANOSIDASE (Podosporaanserina) |
PF03664(Glyco_hydro_62) | 5 | PHE A 76ALA A 63ILE A 52PHE A 78ILE A 47 | None | 1.11A | 5m24A-4n2zA:undetectable | 5m24A-4n2zA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ns1 | PURINE NUCLEOSIDEPHOSPHORYLASE (Porphyromonasgingivalis) |
PF01048(PNP_UDP_1) | 5 | ALA A 93LEU A 44ILE A 43GLY A 278ILE A 55 | None | 1.07A | 5m24A-4ns1A:undetectable | 5m24A-4ns1A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2w | PUTATIVEENDO-BETA-N-ACETYLGLUCOSAMINIDASE (Streptococcuspneumoniae) |
PF01832(Glucosaminidase) | 5 | PHE A 206ALA A 232ILE A 178GLY A 166LEU A 162 | None | 1.12A | 5m24A-4q2wA:undetectable | 5m24A-4q2wA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfe | ENOYL-COA HYDRATASE (Mycolicibacteriumsmegmatis) |
PF00378(ECH_1) | 5 | PHE A 39ALA A 51ILE A 7GLY A 55LEU A 111 | None | 0.99A | 5m24A-4qfeA:undetectable | 5m24A-4qfeA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfe | ENOYL-COA HYDRATASE (Mycolicibacteriumsmegmatis) |
PF00378(ECH_1) | 5 | TRP A 114PHE A 39ALA A 51ILE A 7GLY A 55 | EDO A 303 (-3.6A)NoneNoneNoneNone | 1.08A | 5m24A-4qfeA:undetectable | 5m24A-4qfeA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qi3 | CELLOBIOSEDEHYDROGENASE (Crassicarponhotsonii) |
PF16010(CDH-cyt) | 5 | ALA A 109LEU A 78ILE A 80SER A 92PHE A 51 | None | 1.06A | 5m24A-4qi3A:undetectable | 5m24A-4qi3A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txk | PROTEIN-METHIONINESULFOXIDE OXIDASEMICAL1 (Mus musculus) |
PF00307(CH)PF01494(FAD_binding_3) | 5 | ALA A 363LEU A 330ARG A 358GLY A 307ILE A 238 | None | 1.12A | 5m24A-4txkA:undetectable | 5m24A-4txkA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y68 | PUTATIVENISIN-RESISTANCEPROTEIN (Streptococcusagalactiae) |
no annotation | 5 | LEU C 48ILE C 47SER C 83GLY C 55ILE C 66 | None | 1.08A | 5m24A-4y68C:undetectable | 5m24A-4y68C:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5s | ACETIC ACID (Talaromycescellulolyticus) |
PF13472(Lipase_GDSL_2) | 5 | ALA A 163ILE A 130GLY A 8LEU A 6ILE A 125 | None | 1.05A | 5m24A-5b5sA:undetectable | 5m24A-5b5sA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c78 | ATP-DRIVEN FLIPPASEPGLK (Campylobacterjejuni) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | ALA A 461ILE A 443GLY A 426LEU A 508ILE A 530 | None | 1.01A | 5m24A-5c78A:undetectable | 5m24A-5c78A:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | ALA A 669LEU A 590SER A 148GLY A 30ILE A 684 | None | 1.11A | 5m24A-5chcA:undetectable | 5m24A-5chcA:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dzt | CYLM (Enterococcusfaecalis) |
PF05147(LANC_like)PF13575(DUF4135) | 5 | PHE A 286ILE A 492PHE A 343GLY A 338ILE A 298 | None | 1.10A | 5m24A-5dztA:undetectable | 5m24A-5dztA:12.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEASOME SUBUNITALPHA TYPE (Plasmodiumfalciparum) |
PF00227(Proteasome)PF10584(Proteasome_A_N) | 5 | ALA C 192ILE C 33GLY C 75LEU C 147ILE C 44 | None | 1.09A | 5m24A-5fmgC:undetectable | 5m24A-5fmgC:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2v | IMPORTIN SUBUNITBETA-3 (Saccharomycescerevisiae) |
PF13513(HEAT_EZ) | 5 | LEU A 728ILE A 727SER A 773LEU A 628ILE A 704 | None | 1.12A | 5m24A-5h2vA:undetectable | 5m24A-5h2vA:12.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb4 | NUP192,NUCLEOPORINNUP192 (Chaetomiumthermophilum) |
PF11894(Nup192) | 5 | ALA B1342LEU B1321SER B1212PHE B1330LEU B1375 | None | 1.13A | 5m24A-5hb4B:undetectable | 5m24A-5hb4B:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hpl | RSP5 (Saccharomycescerevisiae) |
PF00632(HECT) | 5 | ALA A 468LEU A 507GLY A 555LEU A 480ILE A 457 | None | 1.09A | 5m24A-5hplA:undetectable | 5m24A-5hplA:22.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5k13 | RETINOIC ACIDRECEPTOR ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 9 | TRP A 225PHE A 228LEU A 269ILE A 273ARG A 276SER A 287PHE A 302GLY A 391LEU A 398 | None6Q7 A 501 (-3.9A)6Q7 A 501 (-3.7A)6Q7 A 501 ( 3.9A)6Q7 A 501 (-3.2A)6Q7 A 501 (-2.9A)6Q7 A 501 ( 4.3A)6Q7 A 501 ( 4.1A)None | 0.72A | 5m24A-5k13A:36.8 | 5m24A-5k13A:81.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko5 | PURINE NUCLEOSIDEPHOSPHORYLASE (Schistosomamansoni) |
PF01048(PNP_UDP_1) | 5 | ILE A 19PHE A 58GLY A 68LEU A 87ILE A 32 | None | 1.08A | 5m24A-5ko5A:undetectable | 5m24A-5ko5A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lkq | DNA REPAIR PROTEINRADA (Streptococcuspneumoniae) |
PF13541(ChlI) | 5 | ALA A 412ILE A 293SER A 277GLY A 391ILE A 409 | None | 1.01A | 5m24A-5lkqA:undetectable | 5m24A-5lkqA:24.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m60 | BETA-1,3-GLUCANASE (Chaetomiumthermophilum) |
PF12708(Pectate_lyase_3) | 5 | PHE A 229ALA A 236ILE A 184SER A 182ILE A 257 | None | 0.98A | 5m24A-5m60A:undetectable | 5m24A-5m60A:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n94 | CG9323, ISOFORM A (Drosophilamelanogaster) |
no annotation | 5 | MET A 646ILE A 770SER A 761PHE A 852LEU A 888 | None | 1.04A | 5m24A-5n94A:undetectable | 5m24A-5n94A:14.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR BETA (Homo sapiens) |
no annotation | 11 | TRP B 218PHE B 221ALA B 225LEU B 262ILE B 266ARG B 269SER B 280PHE B 295GLY B 384LEU B 391ILE B 403 | NoneREA B 503 ( 4.8A)REA B 503 (-3.8A)REA B 503 (-3.9A)REA B 503 (-3.6A)REA B 503 ( 4.8A)REA B 503 (-2.1A)REA B 503 ( 4.0A)REA B 503 ( 4.4A)NoneREA B 503 ( 4.7A) | 0.55A | 5m24A-5uanB:37.8 | 5m24A-5uanB:62.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uib | OXIDOREDUCTASEPROTEIN (Agrobacteriumtumefaciens) |
PF01408(GFO_IDH_MocA) | 5 | PHE A 63ALA A 59ILE A 73SER A 79GLY A 8 | NoneNAD A 401 ( 4.6A)NoneNAD A 401 (-2.8A)None | 1.08A | 5m24A-5uibA:undetectable | 5m24A-5uibA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0s | 60 KDA CHAPERONIN (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 5 | ALA A 223LEU A 221ILE A 220LEU A 200ILE A 227 | None | 1.00A | 5m24A-5w0sA:undetectable | 5m24A-5w0sA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wea | PROTEIN ARGONAUTE-2 (Homo sapiens) |
no annotation | 5 | ALA A 690LEU A 650ILE A 651GLY A 616ILE A 687 | NoneIPH A 901 (-4.7A)IPH A 901 ( 4.7A)NoneNone | 1.10A | 5m24A-5weaA:undetectable | 5m24A-5weaA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wjc | KINETOCHORE PROTEINMIS16 (Schizosaccharomycespombe) |
no annotation | 5 | ALA A 92LEU A 77ILE A 76GLY A 399ILE A 122 | None | 1.12A | 5m24A-5wjcA:undetectable | 5m24A-5wjcA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wqn | PROBABLEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00106(adh_short) | 5 | ALA A 117LEU A 80ILE A 81GLY A 128LEU A 172 | None | 1.04A | 5m24A-5wqnA:undetectable | 5m24A-5wqnA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgv | PYRE3 (Streptomycesrugosporus) |
no annotation | 5 | ALA A 76LEU A 283SER A 332PHE A 217GLY A 215 | None | 1.00A | 5m24A-5xgvA:undetectable | 5m24A-5xgvA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmr | SERINEHYDROXYMETHYLTRANSFERASE (Plasmodiumvivax) |
no annotation | 5 | ALA A 397LEU A 342ILE A 337PHE A 415ILE A 349 | None | 1.07A | 5m24A-5xmrA:undetectable | 5m24A-5xmrA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ft1 | FLAVODOXIN (Bacillus cereus) |
no annotation | 5 | ALA A 44ILE A 36GLY A 52LEU A 110ILE A 79 | None | 1.11A | 5m24A-6ft1A:undetectable | 5m24A-6ft1A:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fx0 | RETINOIC ACIDRECEPTOR GAMMA (Homo sapiens) |
no annotation | 11 | TRP A 227PHE A 230ALA A 234LEU A 271ILE A 275ARG A 278SER A 289PHE A 304GLY A 393LEU A 400ILE A 412 | NoneE9T A 501 (-4.3A)E9T A 501 (-3.7A)E9T A 501 (-3.6A)E9T A 501 (-3.8A)E9T A 501 (-3.1A)E9T A 501 (-2.6A)E9T A 501 (-4.2A)E9T A 501 (-3.7A)NoneE9T A 501 ( 4.8A) | 0.54A | 5m24A-6fx0A:40.5 | 5m24A-6fx0A:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fx0 | RETINOIC ACIDRECEPTOR GAMMA (Homo sapiens) |
no annotation | 10 | TRP A 227PHE A 230ALA A 234LEU A 271MET A 272ILE A 275ARG A 278SER A 289PHE A 304ILE A 412 | NoneE9T A 501 (-4.3A)E9T A 501 (-3.7A)E9T A 501 (-3.6A)NoneE9T A 501 (-3.8A)E9T A 501 (-3.1A)E9T A 501 (-2.6A)E9T A 501 (-4.2A)E9T A 501 ( 4.8A) | 0.69A | 5m24A-6fx0A:40.5 | 5m24A-6fx0A:17.80 |