SIMILAR PATTERNS OF AMINO ACIDS FOR 5M0O_C_EPAC502

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhg BETA-GLUCURONIDASE

(Homo sapiens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 LEU A 585
ILE A 404
PHE A 345
ARG A 382
 None
 1.05A 5m0oC-1bhgA:
0.0		 5m0oC-1bhgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g61 TRANSLATION
INITIATION FACTOR 6

(Methanocaldococcus
jannaschii) 		PF01912
(eIF-6) 		4 LEU A2044
ILE A2201
ALA A2019
PHE A2009
 None
 0.95A 5m0oC-1g61A:
undetectable		 5m0oC-1g61A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 ILE A 448
PRO A 163
ALA A 157
PHE A 166
 None
 0.90A 5m0oC-1hcyA:
0.0		 5m0oC-1hcyA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ile ISOLEUCYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 LEU A 162
ILE A 515
PRO A 455
PRO A 532
 None
 1.05A 5m0oC-1ileA:
0.0		 5m0oC-1ileA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itu RENAL DIPEPTIDASE

(Homo sapiens) 		PF01244
(Peptidase_M19) 		4 LEU A 330
ILE A 109
PHE A 334
ALA A 119
 None
 1.01A 5m0oC-1ituA:
undetectable		 5m0oC-1ituA:
21.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1izo CYTOCHROME P450
152A1

(Bacillus
subtilis) 		PF00067
(p450) 		5 LEU A  78
ARG A 242
PRO A 243
ALA A 246
PHE A 289
 PAM  A 601 ( 4.7A)
PAM  A 601 (-3.7A)
PAM  A 601 (-3.9A)
PAM  A 601 (-3.9A)
HEM  A 501 ( 4.0A)
 0.31A 5m0oC-1izoA:
56.5		 5m0oC-1izoA:
41.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1izo CYTOCHROME P450
152A1

(Bacillus
subtilis) 		PF00067
(p450) 		5 LEU A  78
PHE A 173
ARG A 242
PRO A 243
ALA A 246
 PAM  A 601 ( 4.7A)
PAM  A 601 ( 4.2A)
PAM  A 601 (-3.7A)
PAM  A 601 (-3.9A)
PAM  A 601 (-3.9A)
 0.66A 5m0oC-1izoA:
56.5		 5m0oC-1izoA:
41.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		4 LEU A 550
PHE A 554
PRO A 521
ALA A 524
 None
 0.96A 5m0oC-1j1wA:
0.0		 5m0oC-1j1wA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m64 FLAVOCYTOCHROME C3

(Shewanella
frigidimarina) 		PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2) 		4 ILE A 409
ALA A 417
PHE A 395
PRO A 483
 None
 0.78A 5m0oC-1m64A:
0.0		 5m0oC-1m64A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n94 PROTEIN
FARNESYLTRANSFERASE
BETA SUBUNIT

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		4 LEU B 150
PHE B 191
ALA B 211
PHE B 222
 None
 0.91A 5m0oC-1n94B:
undetectable		 5m0oC-1n94B:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nzi COMPLEMENT C1S
COMPONENT

(Homo sapiens) 		PF00431
(CUB)
PF14670
(FXa_inhibition) 		4 LEU A  42
PHE A  39
PHE A  84
PRO A  79
 None
 1.02A 5m0oC-1nziA:
undetectable		 5m0oC-1nziA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s8e EXONUCLEASE PUTATIVE

(Pyrococcus
furiosus) 		PF00149
(Metallophos) 		4 LEU A 304
ILE A 278
ALA A 288
PHE A 245
 None
 0.91A 5m0oC-1s8eA:
undetectable		 5m0oC-1s8eA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5f PYRUVATE OXIDASE

(Aerococcus
viridans) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A 237
PHE A 282
ALA A 265
PRO A 412
 None
FAD  A1601 (-4.1A)
None
FAD  A1601 (-4.0A)
 0.82A 5m0oC-1v5fA:
undetectable		 5m0oC-1v5fA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zhq MANNAN-BINDING
LECTIN

(Microcystis
viridis) 		PF12151
(MVL) 		4 ILE A  25
PHE A  33
PRO A   8
ALA A   9
 None
 1.04A 5m0oC-1zhqA:
undetectable		 5m0oC-1zhqA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bma GLUTAMATE
DEHYDROGENASE
(NADP+)

(Plasmodium
falciparum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 LEU A  32
ILE A  48
PHE A 108
PRO A 368
 None
 0.89A 5m0oC-2bmaA:
undetectable		 5m0oC-2bmaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ee4 RHO GTPASE
ACTIVATING PROTEIN 5
VARIANT

(Homo sapiens) 		PF00620
(RhoGAP) 		4 LEU A  73
ILE A  61
ALA A  86
PHE A  30
 None
 0.75A 5m0oC-2ee4A:
undetectable		 5m0oC-2ee4A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7n RNA-DEPENDENT RNA
POLYMERASE

(Neurospora
crassa) 		PF05183
(RdRP) 		4 ILE A1231
ARG A1305
ALA A1309
PHE A1320
 None
 0.93A 5m0oC-2j7nA:
undetectable		 5m0oC-2j7nA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l2f CYANOVIRIN-N HOMOLOG

(Fusarium
graminearum) 		PF08881
(CVNH) 		4 LEU A  13
ILE A  62
ALA A  77
PHE A  48
 None
 0.92A 5m0oC-2l2fA:
undetectable		 5m0oC-2l2fA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l2f CYANOVIRIN-N HOMOLOG

(Fusarium
graminearum) 		PF08881
(CVNH) 		4 LEU A  64
ILE A  11
ALA A  21
PHE A   4
 None
 1.01A 5m0oC-2l2fA:
undetectable		 5m0oC-2l2fA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmo SER/THR PROTEIN
KINASE

(Plasmodium
falciparum) 		PF00069
(Pkinase) 		4 ILE X 310
ALA X 315
PHE X 297
PRO X 246
 None
 0.98A 5m0oC-2pmoX:
undetectable		 5m0oC-2pmoX:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzx CANDIDAPEPSIN-5

(Candida
albicans) 		PF00026
(Asp) 		5 LEU A 270
PHE A 266
PRO A 329
ALA A 314
PHE A 310
 None
 0.93A 5m0oC-2qzxA:
undetectable		 5m0oC-2qzxA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsi 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Streptococcus
pneumoniae) 		PF01128
(IspD) 		4 LEU A   7
ARG A  85
ALA A 196
PHE A 173
 CDF  A1234 (-3.8A)
CDF  A1234 (-3.5A)
None
None
 0.83A 5m0oC-2vsiA:
undetectable		 5m0oC-2vsiA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf2 CATALASE

(Penicillium
janthinellum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 LEU A 153
PHE A 143
ALA A 106
PRO A 292
 None
 0.97A 5m0oC-2xf2A:
undetectable		 5m0oC-2xf2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xik SERINE/THREONINE
PROTEIN KINASE 25

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 121
ILE A 117
ALA A 209
PRO A 259
 None
 1.03A 5m0oC-2xikA:
undetectable		 5m0oC-2xikA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc0 ALANINE GLYOXYLATE
TRANSAMINASE

(Thermococcus
litoralis) 		PF00155
(Aminotran_1_2) 		4 LEU A 291
PHE A 296
PHE A 219
PRO A  50
 None
 0.72A 5m0oC-2zc0A:
undetectable		 5m0oC-2zc0A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuk ALPHA-AMINO-EPSILON-
CAPROLACTAM RACEMASE

(Achromobacter
obae) 		PF00202
(Aminotran_3) 		4 LEU A 191
ILE A 131
ALA A 202
PHE A 224
 None
 0.79A 5m0oC-2zukA:
undetectable		 5m0oC-2zukA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyj ALPHA-AMINODIPATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 LEU A 240
PHE A 236
ARG A 289
PHE A  82
 None
 0.80A 5m0oC-2zyjA:
undetectable		 5m0oC-2zyjA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2f DNA POLYMERASE
SLIDING CLAMP

(Pyrococcus
furiosus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU B 179
ILE B 177
PHE B 164
ALA B 144
 None
 1.03A 5m0oC-3a2fB:
undetectable		 5m0oC-3a2fB:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 LEU A 204
PHE A 115
ALA A 227
PHE A 184
 None
 1.00A 5m0oC-3aqpA:
undetectable		 5m0oC-3aqpA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8b CYSQ, SULFITE
SYNTHESIS PATHWAY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF00459
(Inositol_P) 		4 ILE A  17
PHE A  25
ALA A  39
PHE A  89
 None
 0.93A 5m0oC-3b8bA:
undetectable		 5m0oC-3b8bA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8k PROTEIN PHOSPHATASE
2C

(Toxoplasma
gondii) 		PF00481
(PP2C) 		4 LEU A 398
ILE A 340
ARG A 396
PRO A 193
 None
 0.89A 5m0oC-3d8kA:
undetectable		 5m0oC-3d8kA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 LEU A 292
ALA A 389
PHE A 343
PRO A 325
 None
 0.76A 5m0oC-3fdhA:
undetectable		 5m0oC-3fdhA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdc MULTICOPPER OXIDASE

(Arthrobacter
sp. FB24) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 269
PHE A 239
PHE A 232
PRO A 250
 None
 1.05A 5m0oC-3gdcA:
undetectable		 5m0oC-3gdcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0l GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Aquifex
aeolicus) 		PF01425
(Amidase) 		4 LEU A 458
ILE A 449
ALA A 424
PRO A 239
 None
 0.90A 5m0oC-3h0lA:
undetectable		 5m0oC-3h0lA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i50 MURINE HEAVY CHAIN
(IGG3) OF E53
MONOCLONAL ANTIBODY
FAB

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU H  48
PHE H  67
PRO H  40
ALA H  88
 None
 0.97A 5m0oC-3i50H:
undetectable		 5m0oC-3i50H:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ld8 BIFUNCTIONAL
ARGININE DEMETHYLASE
AND
LYSYL-HYDROXYLASE
JMJD6

(Homo sapiens) 		PF02373
(JmjC) 		4 PHE A  35
PRO A  39
ALA A  41
PRO A 129
 None
 0.79A 5m0oC-3ld8A:
undetectable		 5m0oC-3ld8A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Streptococcus
pyogenes) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 261
ALA A 244
PHE A 266
PRO A 181
 None
 0.92A 5m0oC-3lgxA:
undetectable		 5m0oC-3lgxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7o LYMPHOCYTE ANTIGEN
86

(Mus musculus) 		PF02221
(E1_DerP2_DerF2) 		4 LEU A  81
PHE A 111
ALA A 153
PHE A  70
 None
None
L9R  A 301 (-3.6A)
L9R  A 301 ( 4.3A)
 0.68A 5m0oC-3m7oA:
undetectable		 5m0oC-3m7oA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcp GLUCOKINASE

(Parabacteroides
distasonis) 		PF00480
(ROK) 		4 LEU A  13
PHE A  73
ALA A  39
PHE A  90
 None
 0.94A 5m0oC-3mcpA:
undetectable		 5m0oC-3mcpA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nuz PUTATIVE ACETYL
XYLAN ESTERASE

(Bacteroides
fragilis) 		PF12715
(Abhydrolase_7) 		4 PHE A  62
ALA A 327
PHE A  71
PRO A  58
 None
 0.97A 5m0oC-3nuzA:
undetectable		 5m0oC-3nuzA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0c NISCHARIN

(Homo sapiens) 		PF00787
(PX) 		4 LEU A 115
ILE A  35
PHE A 114
PHE A  53
 None
 0.77A 5m0oC-3p0cA:
undetectable		 5m0oC-3p0cA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pn1 DNA LIGASE

(Haemophilus
influenzae) 		PF01653
(DNA_ligase_aden) 		4 LEU A 281
ILE A 274
PRO A 115
PHE A 316
 None
 1.06A 5m0oC-3pn1A:
undetectable		 5m0oC-3pn1A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps9 TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC

(Escherichia
coli) 		PF01266
(DAO)
PF05430
(Methyltransf_30) 		4 LEU A  95
PHE A  97
PHE A 176
PRO A 638
 None
 1.03A 5m0oC-3ps9A:
undetectable		 5m0oC-3ps9A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q06 CELLULAR TUMOR
ANTIGEN P53

(Homo sapiens) 		PF00870
(P53)
PF07710
(P53_tetramer) 		4 LEU A 145
ILE A 255
ALA A 159
PHE A 234
 None
 0.86A 5m0oC-3q06A:
undetectable		 5m0oC-3q06A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r97 MALONYL COA-ACP
TRANSACYLASE

(Xanthomonas
oryzae) 		PF00698
(Acyl_transf_1) 		4 LEU A 294
ILE A 271
ALA A   7
PRO A 166
 None
 0.92A 5m0oC-3r97A:
undetectable		 5m0oC-3r97A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rb9 DNA POLYMERASE III
SUBUNIT BETA

(Mycobacterium
tuberculosis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 LEU A 240
ILE A 242
ALA A 214
PHE A 144
 None
 0.92A 5m0oC-3rb9A:
undetectable		 5m0oC-3rb9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sim PROTEIN, FAMILY 18
CHITINASE

(Crocus vernus) 		PF00704
(Glyco_hydro_18) 		4 LEU A 247
ILE A 250
ALA A 269
PHE A 235
 None
 1.04A 5m0oC-3simA:
undetectable		 5m0oC-3simA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t58 SULFHYDRYL OXIDASE 1

(Mus musculus) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		4 PHE A 195
ARG A 220
PRO A 173
ALA A 174
 None
 0.82A 5m0oC-3t58A:
undetectable		 5m0oC-3t58A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1h 3-ISOPROPYLMALATE
DEHYDROGENASE

(Bacillus sp.
(in: Bacteria)) 		PF00180
(Iso_dh) 		4 LEU A  25
ILE A   5
ALA A  68
PHE A 308
 None
 0.79A 5m0oC-3u1hA:
undetectable		 5m0oC-3u1hA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4g NAMN:DMB
PHOSPHORIBOSYLTRANSF
ERASE

(Pyrococcus
horikoshii) 		no annotation 4 ILE A 178
ALA A 151
PHE A 106
PRO A  30
 None
 0.94A 5m0oC-3u4gA:
undetectable		 5m0oC-3u4gA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va7 KLLA0E08119P

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 LEU A 977
ALA A1007
PHE A 982
PRO A1192
 None
 0.98A 5m0oC-3va7A:
undetectable		 5m0oC-3va7A:
16.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3voo FATTY ACID
ALPHA-HYDROXYLASE

(Sphingomonas
paucimobilis) 		PF00067
(p450) 		4 LEU A  77
ARG A 241
PRO A 242
PHE A 287
 None
None
HEM  A 501 (-4.2A)
HEM  A 501 (-3.7A)
 0.51A 5m0oC-3vooA:
54.5		 5m0oC-3vooA:
37.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w4k D-AMINO-ACID OXIDASE

(Homo sapiens) 		PF01266
(DAO) 		4 LEU A 215
ILE A 230
ALA A  49
PRO A 105
 3LD  A 402 (-4.1A)
None
FAD  A 401 ( 4.0A)
None
 0.92A 5m0oC-3w4kA:
undetectable		 5m0oC-3w4kA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zuq BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		4 LEU A 818
ILE A 735
PRO A 824
ALA A 826
 None
 1.01A 5m0oC-3zuqA:
undetectable		 5m0oC-3zuqA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b60 FIBRONECTIN-BINDING
PROTEIN A

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		4 ILE A 265
PHE A 287
ALA A 299
PHE A 233
 None
 0.91A 5m0oC-4b60A:
undetectable		 5m0oC-4b60A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bej DYNAMIN 1-LIKE
PROTEIN

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		4 LEU A 304
ILE A 308
ALA A 697
PHE A  15
 None
 0.87A 5m0oC-4bejA:
undetectable		 5m0oC-4bejA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bom ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1) 		PF00606
(Glycoprotein_B)
PF17416
(Glycoprot_B_PH1)
PF17417
(Glycoprot_B_PH2) 		4 ILE A 501
ARG A 505
ALA A 504
PHE A 395
 None
 1.04A 5m0oC-4bomA:
undetectable		 5m0oC-4bomA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eo9 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Mycobacterium
leprae) 		PF00300
(His_Phos_1) 		4 ILE A 213
PRO A 235
ALA A 238
PRO A 225
 None
 1.05A 5m0oC-4eo9A:
undetectable		 5m0oC-4eo9A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Xanthomonas
campestris) 		PF00563
(EAL) 		4 LEU A 181
ILE A 199
ALA A 230
PRO A 176
 None
 0.79A 5m0oC-4f48A:
undetectable		 5m0oC-4f48A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gak ACYL-ACP
THIOESTERASE

(Spirosoma
linguale) 		PF01643
(Acyl-ACP_TE) 		4 LEU A  58
PHE A  61
ALA A  35
PHE A  93
 None
None
GOL  A 302 (-3.6A)
None
 0.69A 5m0oC-4gakA:
undetectable		 5m0oC-4gakA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1g MALTOSE BINDING
PROTEIN-CAKAR3 MOTOR
DOMAIN FUSION
PROTEIN

(Candida
albicans;
Escherichia
coli) 		PF00225
(Kinesin)
PF13416
(SBP_bac_8) 		4 ILE A 530
PRO A 533
ALA A 536
PHE A 565
 None
 0.70A 5m0oC-4h1gA:
undetectable		 5m0oC-4h1gA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb4 EXPORTIN-1

(Saccharomyces
cerevisiae) 		PF03810
(IBN_N)
PF08389
(Xpo1)
PF08767
(CRM1_C) 		4 LEU C 315
PHE C 318
ALA C 343
PHE C 279
 None
 0.99A 5m0oC-4hb4C:
undetectable		 5m0oC-4hb4C:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hne PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA

(Homo sapiens) 		PF00454
(PI3_PI4_kinase) 		4 PHE A 110
ARG A 115
ALA A 117
PHE A 260
 PHE  A 110 ( 1.3A)
ARG  A 115 ( 0.6A)
ALA  A 117 ( 0.0A)
PHE  A 260 ( 1.3A)
 1.05A 5m0oC-4hneA:
undetectable		 5m0oC-4hneA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hzz NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 LEU A 397
ILE A 376
PHE A 374
PHE A 352
 None
 0.86A 5m0oC-4hzzA:
undetectable		 5m0oC-4hzzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ij3 SULFHYDRYL OXIDASE 1

(Homo sapiens) 		PF00085
(Thioredoxin) 		4 PHE A 192
ARG A 217
PRO A 170
ALA A 171
 None
 0.89A 5m0oC-4ij3A:
undetectable		 5m0oC-4ij3A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4izk YELLOWTAIL ASCITES
VIRUS (YAV) VP4
PROTEASE

(Yellowtail
ascites virus) 		PF01768
(Birna_VP4) 		4 LEU A 638
ILE A 592
ALA A 629
PRO A 650
 None
 0.85A 5m0oC-4izkA:
undetectable		 5m0oC-4izkA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j30 PUTATIVE PERIPLASMIC
PROTEIN

(Salmonella
enterica) 		PF16695
(Tai4) 		4 LEU B 120
ILE B  83
ALA B  44
PHE B 111
 None
 1.05A 5m0oC-4j30B:
undetectable		 5m0oC-4j30B:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jix PROJANNALYSIN

(Methanocaldococcus
jannaschii) 		PF01863
(DUF45) 		4 LEU A  63
ILE A  66
PHE A  58
ALA A  39
 None
 1.05A 5m0oC-4jixA:
undetectable		 5m0oC-4jixA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kmh SUPPRESSOR OF FUSED
HOMOLOG

(Homo sapiens) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		4 LEU A 223
ILE A 219
ALA A 211
PRO A 183
 None
 0.99A 5m0oC-4kmhA:
undetectable		 5m0oC-4kmhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1b POLYSACCHARIDE
DEACETYLASE

(Bacillus
anthracis) 		PF01522
(Polysacc_deac_1) 		4 LEU A 222
ILE A  75
ALA A 211
PHE A  89
 None
 1.01A 5m0oC-4m1bA:
undetectable		 5m0oC-4m1bA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2l SULFHYDRYL OXIDASE 1

(Rattus
norvegicus) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		4 PHE A 195
ARG A 220
PRO A 173
ALA A 174
 None
 0.81A 5m0oC-4p2lA:
undetectable		 5m0oC-4p2lA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 LEU A 753
ARG A 750
ALA A 746
PRO A 328
 None
 0.86A 5m0oC-4q2cA:
undetectable		 5m0oC-4q2cA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qi3 CELLOBIOSE
DEHYDROGENASE

(Crassicarpon
hotsonii) 		PF16010
(CDH-cyt) 		4 LEU A  55
ILE A  80
PHE A  35
PHE A  51
 None
 0.95A 5m0oC-4qi3A:
undetectable		 5m0oC-4qi3A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz0 ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 ILE A 534
PRO A 553
ALA A 556
PHE A 592
 None
 0.99A 5m0oC-4tz0A:
undetectable		 5m0oC-4tz0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upi SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 LEU A 297
ILE A 238
PRO A 240
ALA A 194
 None
 1.05A 5m0oC-4upiA:
undetectable		 5m0oC-4upiA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6g OXYR

(Pseudomonas
aeruginosa) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 LEU A 289
ILE A 145
ALA A  97
PHE A 106
 None
 0.98A 5m0oC-4x6gA:
undetectable		 5m0oC-4x6gA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj6 VC0179-LIKE PROTEIN

(Escherichia
coli) 		no annotation 4 LEU A 151
ILE A  89
ALA A  52
PRO A 145
 None
 0.92A 5m0oC-4xj6A:
undetectable		 5m0oC-4xj6A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zg5 5'-NUCLEOTIDASE SURE

(Brucella
abortus) 		no annotation 4 LEU D  16
ILE D  11
PRO D  35
ALA D  63
 None
 1.05A 5m0oC-4zg5D:
undetectable		 5m0oC-4zg5D:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6d DNA POLYMERASE
SLIDING CLAMP

(Thermococcus
gammatolerans) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A 179
ILE A 177
PHE A 164
ALA A 144
 None
 0.72A 5m0oC-5a6dA:
undetectable		 5m0oC-5a6dA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aee ALPHA-GLUCOSIDASE
YIHQ

(Escherichia
coli) 		PF01055
(Glyco_hydro_31) 		4 LEU A 592
PHE A 591
PHE A 139
PRO A 631
 None
 0.98A 5m0oC-5aeeA:
undetectable		 5m0oC-5aeeA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6a PREDICTED ATPASE OF
THE ABC CLASS

(Vibrio
vulnificus) 		PF09818
(ABC_ATPase) 		4 ILE A 146
ALA A  51
PHE A 118
PRO A 123
 None
 0.81A 5m0oC-5d6aA:
undetectable		 5m0oC-5d6aA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d8i SULFHYDRYL OXIDASE 1

(Mus musculus) 		PF00085
(Thioredoxin) 		4 PHE A 195
ARG A 220
PRO A 173
ALA A 174
 None
 0.94A 5m0oC-5d8iA:
undetectable		 5m0oC-5d8iA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN

(Collinsella
aerofaciens) 		PF00106
(adh_short) 		4 LEU A 186
ILE A 184
ALA A 221
PHE A  24
 None
 0.71A 5m0oC-5fydA:
undetectable		 5m0oC-5fydA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5glg FUMARATE REDUCTASE 2

(Saccharomyces
cerevisiae) 		PF00890
(FAD_binding_2) 		4 ILE A 333
ALA A 344
PHE A 319
PRO A 409
 None
 0.87A 5m0oC-5glgA:
undetectable		 5m0oC-5glgA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Dictyostelium
discoideum;
Homo sapiens) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 LEU A 380
ILE A 378
ALA A 397
PHE A 411
 None
 0.98A 5m0oC-5i4eA:
undetectable		 5m0oC-5i4eA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 LEU A 977
ALA A1007
PHE A 982
PRO A1192
 None
 0.98A 5m0oC-5i8iA:
undetectable		 5m0oC-5i8iA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1r BURKHOLDERIA
PSEUDOMALLEI
SPHINGOSINE-1-PHOSPH
ATE LYASE BPSS2021

(Burkholderia
pseudomallei) 		PF00282
(Pyridoxal_deC) 		4 LEU A 358
PHE A 370
ALA A 424
PRO A 397
 None
 0.85A 5m0oC-5k1rA:
undetectable		 5m0oC-5k1rA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1u NAD(P)H:FLAVIN
OXIDOREDUCTASE SYE4

(Shewanella
oneidensis) 		PF00724
(Oxidored_FMN) 		4 LEU A  43
ILE A  68
PRO A  71
ALA A  73
 None
 1.00A 5m0oC-5k1uA:
undetectable		 5m0oC-5k1uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m49 AMINOTRANSFERASE
CLASS-III

(Rhizobium
freirei) 		PF00202
(Aminotran_3) 		4 LEU A 191
ILE A 131
ALA A 202
PHE A 224
 None
 0.84A 5m0oC-5m49A:
undetectable		 5m0oC-5m49A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyl INNER TEGUMENT
PROTEIN

(Human
alphaherpesvirus
1) 		PF03970
(Herpes_UL37_1) 		4 ILE A 140
ALA A 172
PHE A 230
PRO A 123
 None
 1.04A 5m0oC-5vylA:
undetectable		 5m0oC-5vylA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0g SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		no annotation 4 LEU A 224
ILE A 156
PHE A 219
ALA A 198
 None
 0.91A 5m0oC-5w0gA:
undetectable		 5m0oC-5w0gA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1e ICMW

(Legionella
pneumophila) 		no annotation 4 ILE B  71
ARG B  72
PRO B 114
ALA B 115
 None
 1.00A 5m0oC-5x1eB:
undetectable		 5m0oC-5x1eB:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ybw ASPARTATE RACEMASE

(Scapharca
broughtonii) 		no annotation 4 LEU A 186
ILE A 268
PHE A 212
PHE A 309
 None
 0.97A 5m0oC-5ybwA:
undetectable		 5m0oC-5ybwA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yhj CYTOCHROME P450

(Exiguobacterium
sp. AT1b) 		no annotation 5 LEU A  78
ARG A 239
PRO A 240
ALA A 243
PHE A 285
 None
MYR  A 502 (-4.2A)
MYR  A 502 ( 3.7A)
MYR  A 502 (-3.7A)
HEM  A 501 ( 3.9A)
 0.44A 5m0oC-5yhjA:
55.1		 5m0oC-5yhjA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b1p GLUTAMATE--TRNA
LIGASE 1

(Helicobacter
pylori) 		PF00749
(tRNA-synt_1c) 		4 LEU A 261
ILE A  18
PHE A 264
PHE A 299
 None
 1.04A 5m0oC-6b1pA:
undetectable		 5m0oC-6b1pA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c54 NUCLEOPROTEIN

(Zaire
ebolavirus) 		no annotation 4 LEU A  77
PHE A 150
ALA A  70
PHE A  60
 None
 0.77A 5m0oC-6c54A:
undetectable		 5m0oC-6c54A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cj7 SERPIN-12

(Manduca sexta) 		no annotation 4 LEU A 312
ILE A 314
PHE A 161
PHE A 215
 None
 0.88A 5m0oC-6cj7A:
undetectable		 5m0oC-6cj7A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d4j PROTEIN PATCHED
HOMOLOG 1

(Homo sapiens) 		no annotation 4 LEU A1140
PHE A1152
PRO A 504
PHE A 573
 None
 1.02A 5m0oC-6d4jA:
undetectable		 5m0oC-6d4jA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g42 MINOR CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus) 		no annotation 4 LEU A 285
ILE A 200
PHE A 273
PHE A  52
 None
 0.98A 5m0oC-6g42A:
undetectable		 5m0oC-6g42A:
11.85