SIMILAR PATTERNS OF AMINO ACIDS FOR 5M0I_B_ACTB303_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ao0 GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE

(Bacillus
subtilis) 		PF00156
(Pribosyltran)
PF13522
(GATase_6) 		4 VAL A 106
THR A 447
ASN A 175
ASP A 173
 None
 1.20A 5m0iB-1ao0A:
0.0		 5m0iB-1ao0A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyg CYCLODEXTRIN
GLUCANOTRANSFERASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 VAL A 414
ASN A 437
ASP A 477
LEU A 478
 None
 1.30A 5m0iB-1cygA:
0.0		 5m0iB-1cygA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dk5 ANNEXIN 24(CA32)

(Capsicum annuum) 		PF00191
(Annexin) 		4 VAL A  87
THR A 276
ASP A  96
LEU A  99
 None
None
None
SO4  A 801 ( 4.9A)
 1.21A 5m0iB-1dk5A:
undetectable		 5m0iB-1dk5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN

(Propionibacterium
freudenreichii) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		4 VAL A  46
THR A  40
ASN A 293
LEU A 412
 None
 1.11A 5m0iB-1e1cA:
0.0		 5m0iB-1e1cA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 VAL A 317
THR A 407
ASN A 409
LEU A 403
 None
 1.06A 5m0iB-1g8kA:
undetectable		 5m0iB-1g8kA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hx8 SYNAPSE-ENRICHED
CLATHRIN ADAPTOR
PROTEIN LAP

(Drosophila
melanogaster) 		PF07651
(ANTH) 		4 VAL A 267
ASN A 200
ASP A 201
LEU A 202
 None
 1.11A 5m0iB-1hx8A:
1.4		 5m0iB-1hx8A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ji6 PESTICIDIAL CRYSTAL
PROTEIN CRY3BB

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 VAL A 568
ASN A 584
ASP A 588
LEU A 590
 None
 1.09A 5m0iB-1ji6A:
0.3		 5m0iB-1ji6A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkr 3-METHYLASPARTATE
AMMONIA-LYASE

(Citrobacter
amalonaticus) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		4 VAL A 153
THR A 142
ASP A 140
LEU A 139
 None
 1.08A 5m0iB-1kkrA:
0.0		 5m0iB-1kkrA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mf1 ADENYLOSUCCINATE
SYNTHETASE

(Mus musculus) 		PF00709
(Adenylsucc_synt) 		4 VAL A 353
THR A 276
ASN A 274
ASP A 263
 None
 1.17A 5m0iB-1mf1A:
undetectable		 5m0iB-1mf1A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua2 CELL DIVISION
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A  38
THR A  34
ASP A  79
LEU A  78
 None
 1.28A 5m0iB-1ua2A:
0.0		 5m0iB-1ua2A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaa PROTEIN
(ATP-DEPENDENT DNA
HELICASE REP.)

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		4 THR A  83
ASN A  57
ASP A 538
LEU A 536
 None
 1.24A 5m0iB-1uaaA:
undetectable		 5m0iB-1uaaA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xoc OLIGOPEPTIDE-BINDING
PROTEIN APPA

(Bacillus
subtilis) 		PF00496
(SBP_bac_5) 		4 VAL A 372
THR A 245
ASP A 304
LEU A 301
 None
None
ZN  A 523 (-2.1A)
None
 1.01A 5m0iB-1xocA:
undetectable		 5m0iB-1xocA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xw8 UPF0271 PROTEIN YBGL

(Escherichia
coli) 		PF03746
(LamB_YcsF) 		4 VAL A  23
ASN A  27
ASP A   8
LEU A   9
 None
 1.20A 5m0iB-1xw8A:
undetectable		 5m0iB-1xw8A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2alb PROTEIN
DISULFIDE-ISOMERASE
A3

(Homo sapiens) 		PF00085
(Thioredoxin) 		4 VAL A  59
THR A  67
ASN A  66
ASP A   8
 None
 1.35A 5m0iB-2albA:
undetectable		 5m0iB-2albA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2az4 HYPOTHETICAL PROTEIN
EF2904

(Enterococcus
faecalis) 		PF12706
(Lactamase_B_2) 		4 VAL A  88
THR A  86
ASP A 105
LEU A  66
 None
 1.25A 5m0iB-2az4A:
undetectable		 5m0iB-2az4A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ee0 PROTOCADHERIN-9

(Homo sapiens) 		PF00028
(Cadherin) 		4 VAL A 110
THR A  85
ASP A  81
LEU A  80
 None
 1.32A 5m0iB-2ee0A:
undetectable		 5m0iB-2ee0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ew2 2-DEHYDROPANTOATE
2-REDUCTASE,
PUTATIVE

(Enterococcus
faecalis) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 VAL A 303
THR A 200
ASP A 265
LEU A 266
 None
 1.28A 5m0iB-2ew2A:
undetectable		 5m0iB-2ew2A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Staphylococcus
aureus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 THR B  37
ASN B 142
ASP B 140
LEU B 141
 None
 1.32A 5m0iB-2f2aB:
undetectable		 5m0iB-2f2aB:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5t ARCHAEAL
TRANSCRIPTIONAL
REGULATOR TRMB

(Thermococcus
litoralis) 		PF11495
(Regulator_TrmB) 		4 VAL X 161
THR X 154
ASP X 150
LEU X 128
 None
 1.24A 5m0iB-2f5tX:
undetectable		 5m0iB-2f5tX:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fuq HEPARINASE II
PROTEIN

(Pedobacter
heparinus) 		PF07940
(Hepar_II_III)
PF16332
(DUF4962) 		4 VAL A 684
THR A 607
ASN A 589
LEU A 609
 None
 1.35A 5m0iB-2fuqA:
undetectable		 5m0iB-2fuqA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fz5 FLAVODOXIN

(Megasphaera
elsdenii) 		PF00258
(Flavodoxin_1) 		4 VAL A  44
THR A  39
ASP A  73
LEU A  74
 None
 1.15A 5m0iB-2fz5A:
undetectable		 5m0iB-2fz5A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2imr HYPOTHETICAL PROTEIN
DR_0824

(Deinococcus
radiodurans) 		PF01979
(Amidohydro_1) 		4 VAL A 354
THR A 351
ASN A  95
LEU A 360
 None
 1.30A 5m0iB-2imrA:
undetectable		 5m0iB-2imrA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5a 30S RIBOSOMAL
PROTEIN S6

(Aquifex
aeolicus) 		PF01250
(Ribosomal_S6) 		5 VAL A  32
THR A  12
ASN A  97
ASP A  83
LEU A  86
 None
 1.46A 5m0iB-2j5aA:
undetectable		 5m0iB-2j5aA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jll NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set)
PF13927
(Ig_3) 		4 VAL A 370
THR A 312
ASP A 396
LEU A 395
 None
 1.34A 5m0iB-2jllA:
undetectable		 5m0iB-2jllA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mgy TRANSLOCATOR PROTEIN

(Mus musculus) 		PF03073
(TspO_MBR) 		4 VAL A 115
THR A 148
ASN A 151
LEU A 112
 None
None
PKA  A 201 ( 4.1A)
None
 1.29A 5m0iB-2mgyA:
2.4		 5m0iB-2mgyA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6

(Azotobacter
vinelandii) 		PF00353
(HemolysinCabind) 		4 VAL A 105
THR A 114
ASN A 135
LEU A 140
 None
 1.27A 5m0iB-2ml1A:
undetectable		 5m0iB-2ml1A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqh PUTATIVE ISOMERASE

(Streptomyces
coelicolor) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A 312
THR A 280
ASP A 270
LEU A 296
 None
 1.19A 5m0iB-2oqhA:
undetectable		 5m0iB-2oqhA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q7t PROTEIN TRAI

(Escherichia
coli) 		PF08751
(TrwC) 		4 VAL A 110
THR A 158
ASN A 145
LEU A 143
 None
 1.27A 5m0iB-2q7tA:
undetectable		 5m0iB-2q7tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1o CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE

(Mus musculus) 		PF03061
(4HBT) 		4 VAL A  65
THR A  68
ASN A 114
LEU A  35
 None
 1.23A 5m0iB-2v1oA:
undetectable		 5m0iB-2v1oA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyx BETA-LACTAMSE TOHO-1

(Escherichia
coli) 		PF13354
(Beta-lactamase2) 		4 VAL A  74
ASN A 214
ASP A 233
LEU A 211
 None
 1.33A 5m0iB-2wyxA:
undetectable		 5m0iB-2wyxA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x30 PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
coelicolor) 		PF00977
(His_biosynth) 		4 VAL A  18
ASN A  63
ASP A  53
LEU A  54
 None
 1.27A 5m0iB-2x30A:
undetectable		 5m0iB-2x30A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy1 NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF07679
(I-set) 		4 VAL A 370
THR A 312
ASP A 396
LEU A 395
 None
 1.29A 5m0iB-2xy1A:
undetectable		 5m0iB-2xy1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yew CAPSID PROTEIN

(Barmah Forest
virus) 		PF00944
(Peptidase_S3) 		4 VAL A 159
THR A 145
ASP A 137
LEU A 141
 None
 1.33A 5m0iB-2yewA:
undetectable		 5m0iB-2yewA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 THR A 351
ASN A 280
ASP A 348
LEU A 349
 None
 1.26A 5m0iB-2zu6A:
undetectable		 5m0iB-2zu6A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
anthracis) 		PF02350
(Epimerase_2) 		4 VAL A  86
THR A  39
ASP A  62
LEU A  63
 None
 1.35A 5m0iB-3beoA:
undetectable		 5m0iB-3beoA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvz S-LAYER PROTEIN

(Clostridioides
difficile) 		PF12211
(LMWSLP_N) 		4 VAL A 247
ASN A  39
ASP A  79
LEU A  75
 None
 1.24A 5m0iB-3cvzA:
undetectable		 5m0iB-3cvzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddn D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00389
(2-Hacid_dh)
PF01842
(ACT)
PF02826
(2-Hacid_dh_C) 		4 VAL A 315
THR A 383
ASP A 329
LEU A 328
 None
 1.26A 5m0iB-3ddnA:
undetectable		 5m0iB-3ddnA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdz ARGINYL-TRNA
SYNTHETASE

(Klebsiella
pneumoniae) 		PF03485
(Arg_tRNA_synt_N) 		4 VAL A  75
ASN A  69
ASP A  67
LEU A  68
 None
EDO  A 109 ( 4.6A)
None
None
 1.29A 5m0iB-3gdzA:
undetectable		 5m0iB-3gdzA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gff IROE-LIKE SERINE
HYDROLASE

(Shewanella
oneidensis) 		PF00756
(Esterase) 		4 VAL A 149
ASN A  82
ASP A  49
LEU A  48
 None
 1.32A 5m0iB-3gffA:
undetectable		 5m0iB-3gffA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1

(Clostridium
perfringens) 		PF00005
(ABC_tran) 		4 VAL A 150
THR A 139
ASP A  92
LEU A  95
 None
 1.29A 5m0iB-3gfoA:
undetectable		 5m0iB-3gfoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6v PERIPLASMIC
HIS/GLU/GLN/ARG/OPIN
E FAMILY-BINDING
PROTEIN

(Ruegeria
pomeroyi) 		PF00497
(SBP_bac_3) 		4 VAL A  53
THR A 113
ASP A 234
LEU A 237
 None
 1.33A 5m0iB-3i6vA:
undetectable		 5m0iB-3i6vA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3if8 PROTEIN ZWILCH
HOMOLOG
PROTEIN ZWILCH
HOMOLOG

(Homo sapiens;
Homo sapiens) 		PF09817
(Zwilch)
PF09817
(Zwilch) 		4 VAL B 514
ASN A 250
ASP A 228
LEU A 227
 None
 1.03A 5m0iB-3if8B:
undetectable		 5m0iB-3if8B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V BETA CHAIN

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		4 VAL B 327
THR B 186
ASP B 196
LEU B 193
 None
 1.14A 5m0iB-3k70B:
undetectable		 5m0iB-3k70B:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermus
thermophilus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 THR F  37
ASN F 138
ASP F 136
LEU F 137
 None
 1.33A 5m0iB-3kfuF:
undetectable		 5m0iB-3kfuF:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgw ALANINE-GLYOXYLATE
AMINOTRANSFERASE

(Mus musculus) 		PF00266
(Aminotran_5) 		4 THR A 110
ASN A 114
ASP A 265
LEU A 269
 None
 1.32A 5m0iB-3kgwA:
undetectable		 5m0iB-3kgwA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbh PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE

(Bacteroides
thetaiotaomicron) 		PF08543
(Phos_pyr_kin) 		4 VAL A 197
THR A 248
ASP A 245
LEU A 244
 None
 1.28A 5m0iB-3mbhA:
undetectable		 5m0iB-3mbhA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE GAMMA-SUBUNIT

(Komagataella
pastoris) 		no annotation 4 THR I 246
ASN I 247
ASP I  94
LEU I  95
 None
 0.78A 5m0iB-3opyI:
undetectable		 5m0iB-3opyI:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pea ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00378
(ECH_1) 		4 VAL A  51
THR A 190
ASP A 188
LEU A 187
 None
 1.30A 5m0iB-3peaA:
undetectable		 5m0iB-3peaA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qc7 HEAD FIBER PROTEIN

(Bacillus virus
phi29) 		PF11133
(Phage_head_fibr) 		4 THR A 162
ASN A 166
ASP A 153
LEU A 170
 None
 1.26A 5m0iB-3qc7A:
undetectable		 5m0iB-3qc7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4d LACTOSE
PHOSPHORYLASE

(Cellulomonas
uda) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 VAL A 251
THR A 205
ASN A 204
LEU A 263
 None
 1.30A 5m0iB-3s4dA:
undetectable		 5m0iB-3s4dA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sk7 PROTEIN SEQA

(Vibrio cholerae) 		PF03925
(SeqA) 		4 VAL A 115
THR A 123
ASN A 120
ASP A 119
 None
 1.31A 5m0iB-3sk7A:
undetectable		 5m0iB-3sk7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t43 HIV EPITOPE-SCAFFOLD
4E10_1XIZA_S0_006_C

(synthetic
construct) 		PF00359
(PTS_EIIA_2) 		4 VAL A  57
ASN A  95
ASP A  98
LEU A  93
 None
 1.28A 5m0iB-3t43A:
undetectable		 5m0iB-3t43A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr2 OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Coxiella
burnetii) 		PF00215
(OMPdecase) 		4 VAL A  79
ASN A  88
ASP A  62
LEU A  63
 None
 1.13A 5m0iB-3tr2A:
undetectable		 5m0iB-3tr2A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vk9 GLUTATHIONE
S-TRANSFERASE DELTA

(Bombyx mori) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		4 VAL A 156
THR A  72
ASP A  96
LEU A  99
 None
 1.23A 5m0iB-3vk9A:
undetectable		 5m0iB-3vk9A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vs8 TYPE III POLYKETIDE
SYNTHASE

(Azotobacter
vinelandii) 		PF02797
(Chal_sti_synt_C) 		4 VAL A 168
THR A 176
ASP A 215
LEU A 150
 None
 1.07A 5m0iB-3vs8A:
undetectable		 5m0iB-3vs8A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfj 2-DEHYDROPANTOATE
2-REDUCTASE

(Enterococcus
faecium) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 VAL A 302
THR A 199
ASP A 264
LEU A 265
 None
 1.27A 5m0iB-3wfjA:
undetectable		 5m0iB-3wfjA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a25 FERRITIN DPS FAMILY
PROTEIN

(Kineococcus
radiotolerans) 		PF00210
(Ferritin) 		4 VAL A 114
ASN A  55
ASP A  58
LEU A  59
 None
MN  A1172 (-2.6A)
MN  A1172 (-2.8A)
None
 1.35A 5m0iB-4a25A:
3.9		 5m0iB-4a25A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8j ELONGATOR COMPLEX
PROTEIN 4

(Saccharomyces
cerevisiae) 		PF05625
(PAXNEB) 		4 VAL A  75
ASN A 146
ASP A  69
LEU A  68
 None
 1.28A 5m0iB-4a8jA:
undetectable		 5m0iB-4a8jA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4beq ALANINE RACEMASE 2

(Vibrio cholerae) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 VAL A 297
THR A 305
ASP A 353
LEU A 311
 None
 1.24A 5m0iB-4beqA:
undetectable		 5m0iB-4beqA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 VAL A 391
ASN A 570
ASP A 367
LEU A 366
 None
NAG  A3570 (-2.5A)
None
None
 1.22A 5m0iB-4cakA:
undetectable		 5m0iB-4cakA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czb NA(+)/H(+)
ANTIPORTER 1

(Methanocaldococcus
jannaschii) 		PF00999
(Na_H_Exchanger) 		4 THR A 131
ASN A 160
ASP A  93
LEU A  92
 None
 1.33A 5m0iB-4czbA:
undetectable		 5m0iB-4czbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8e GLUTATHIONE
S-TRANSFERASE

(Bombyx mori) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 VAL A 159
THR A  75
ASP A  99
LEU A 102
 None
 1.22A 5m0iB-4e8eA:
undetectable		 5m0iB-4e8eA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fer EXPANSIN-YOAJ

(Bacillus
subtilis) 		PF03330
(DPBB_1) 		4 VAL A  69
ASN A  38
ASP A  41
LEU A  51
 None
 1.25A 5m0iB-4ferA:
undetectable		 5m0iB-4ferA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4frz KINESIN-LIKE
CALMODULIN-BINDING
PROTEIN

(Arabidopsis
thaliana) 		PF00225
(Kinesin) 		4 VAL A1207
THR A1181
ASN A1212
LEU A1175
 None
 1.33A 5m0iB-4frzA:
undetectable		 5m0iB-4frzA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft6 PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 THR A 293
ASN A 291
ASP A 286
LEU A 283
 None
 1.27A 5m0iB-4ft6A:
undetectable		 5m0iB-4ft6A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gib BETA-PHOSPHOGLUCOMUT
ASE

(Clostridioides
difficile) 		PF13419
(HAD_2) 		4 VAL A 123
THR A  14
ASP A  10
LEU A   9
 None
None
PO4  A 303 ( 4.9A)
PO4  A 303 (-3.9A)
 1.24A 5m0iB-4gibA:
undetectable		 5m0iB-4gibA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyi RIO2 KINASE

(Chaetomium
thermophilum) 		PF01163
(RIO1)
PF09202
(Rio2_N) 		4 VAL A  98
THR A   5
ASP A  82
LEU A  86
 None
 1.14A 5m0iB-4gyiA:
undetectable		 5m0iB-4gyiA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4het HYPOTHETICAL
GLYCOSIDE HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13201
(PCMD) 		4 VAL A 191
THR A 179
ASN A 162
LEU A 214
 None
 1.33A 5m0iB-4hetA:
undetectable		 5m0iB-4hetA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idt MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 14

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 539
THR A 552
ASP A 574
LEU A 541
 None
 1.32A 5m0iB-4idtA:
undetectable		 5m0iB-4idtA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL

(Moraxella
catarrhalis) 		PF13360
(PQQ_2) 		4 VAL A 342
ASN A 322
ASP A 324
LEU A 325
 None
 1.08A 5m0iB-4immA:
undetectable		 5m0iB-4immA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrl PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
ovatus) 		PF13201
(PCMD) 		4 VAL A 192
THR A 180
ASN A 163
LEU A 215
 None
 1.31A 5m0iB-4jrlA:
undetectable		 5m0iB-4jrlA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mag SIALIC ACID BINDING
PROTEIN

(Vibrio cholerae) 		PF03480
(DctP) 		4 THR A 266
ASN A 134
ASP A 138
LEU A 133
 None
 1.19A 5m0iB-4magA:
undetectable		 5m0iB-4magA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ng3 5-CARBOXYVANILLATE
DECARBOXYLASE

(Sphingomonas
paucimobilis) 		PF04909
(Amidohydro_2) 		4 VAL A  80
THR A 115
ASN A  96
LEU A  75
 None
 1.30A 5m0iB-4ng3A:
undetectable		 5m0iB-4ng3A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q82 PHOSPHOLIPASE/CARBOX
YLESTERASE

(Haliangium
ochraceum) 		no annotation 4 VAL A 223
THR A 197
ASP A 195
LEU A 194
 None
 1.35A 5m0iB-4q82A:
undetectable		 5m0iB-4q82A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqk LECTIN 2

(Agrocybe
aegerita) 		PF13517
(VCBS) 		4 VAL A  85
THR A  67
ASN A 145
LEU A 149
 None
 1.32A 5m0iB-4tqkA:
undetectable		 5m0iB-4tqkA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvo MALATE DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 VAL A 324
THR A 137
ASN A 138
LEU A 104
 None
 1.32A 5m0iB-4tvoA:
undetectable		 5m0iB-4tvoA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u28 PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
sviceus) 		PF00977
(His_biosynth) 		4 VAL A  22
ASN A  67
ASP A  57
LEU A  58
 None
 1.23A 5m0iB-4u28A:
undetectable		 5m0iB-4u28A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubt ACETYL-COA
ACETYLTRANSFERASE
FADA5

(Mycobacterium
tuberculosis) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 VAL A 349
THR A  61
ASN A 131
LEU A 128
 3G6  A 402 ( 4.7A)
None
None
3G6  A 402 ( 4.3A)
 1.11A 5m0iB-4ubtA:
undetectable		 5m0iB-4ubtA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x2r 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)METHYLIDENEAM
INO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE

(Actinomyces
urogenitalis) 		PF00977
(His_biosynth) 		4 VAL A  16
ASN A  61
ASP A  51
LEU A  52
 None
 1.24A 5m0iB-4x2rA:
undetectable		 5m0iB-4x2rA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9s PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
sp. Mg1) 		PF00977
(His_biosynth) 		4 VAL A  20
ASN A  65
ASP A  55
LEU A  56
 None
 1.23A 5m0iB-4x9sA:
undetectable		 5m0iB-4x9sA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xbk DEOXYRIBOSE-PHOSPHAT
E ALDOLASE

(Lactobacillus
brevis) 		PF01791
(DeoC) 		4 VAL A 186
THR A 159
ASN A 134
ASP A 172
 None
 1.15A 5m0iB-4xbkA:
undetectable		 5m0iB-4xbkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwh ALPHA-N-ACETYLGLUCOS
AMINIDASE

(Homo sapiens) 		PF05089
(NAGLU)
PF12971
(NAGLU_N)
PF12972
(NAGLU_C) 		4 VAL A 609
THR A 564
ASP A 562
LEU A 561
 None
 1.22A 5m0iB-4xwhA:
3.3		 5m0iB-4xwhA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE

(Aspergillus
flavus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 VAL A 335
THR A  98
ASN A 189
ASP A 187
 None
 1.23A 5m0iB-4ynuA:
undetectable		 5m0iB-4ynuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zd6 HALOHYDRIN EPOXIDASE
B

(Corynebacterium
sp.) 		PF13561
(adh_short_C2) 		4 VAL A  51
THR A  14
ASN A  15
LEU A  42
 None
 1.23A 5m0iB-4zd6A:
undetectable		 5m0iB-4zd6A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv3 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE

(Mus musculus) 		PF03061
(4HBT) 		4 VAL A 111
THR A 114
ASN A 160
LEU A  81
 None
 1.30A 5m0iB-4zv3A:
undetectable		 5m0iB-4zv3A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zyl RPHYB PROTEIN

(Rhodopseudomonas
palustris) 		PF00072
(Response_reg) 		4 VAL A  81
THR A  45
ASP A  41
LEU A  76
 None
 1.19A 5m0iB-4zylA:
undetectable		 5m0iB-4zylA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czy LEGIONELLA EFFECTOR
LEGAS4

(Legionella
pneumophila) 		PF00023
(Ank)
PF00856
(SET) 		4 VAL A 217
THR A 190
ASN A 188
ASP A 112
 None
 1.23A 5m0iB-5czyA:
undetectable		 5m0iB-5czyA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzx PROTOCADHERIN BETA 6

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 VAL A 308
THR A 283
ASP A 279
LEU A 278
 None
None
CA  A 518 (-3.0A)
None
 1.32A 5m0iB-5dzxA:
undetectable		 5m0iB-5dzxA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g56 CARBOHYDRATE BINDING
FAMILY 6

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase)
PF03422
(CBM_6) 		4 VAL A 711
ASN A 670
ASP A 663
LEU A 662
 None
 0.89A 5m0iB-5g56A:
undetectable		 5m0iB-5g56A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01547
(SBP_bac_1) 		4 VAL A 256
ASN A 250
ASP A 252
LEU A 254
 None
 1.31A 5m0iB-5g5zA:
undetectable		 5m0iB-5g5zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC

(Zea mays) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 VAL A 177
THR A 125
ASN A 127
LEU A 136
 None
 1.29A 5m0iB-5h8yA:
undetectable		 5m0iB-5h8yA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlq CDPS

(Nocardia
brasiliensis) 		no annotation 4 VAL A 109
THR A 107
ASP A 101
LEU A 100
 None
 1.31A 5m0iB-5mlqA:
undetectable		 5m0iB-5mlqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4a INTRAFLAGELLAR
TRANSPORT PROTEIN 80

(Chlamydomonas
reinhardtii) 		no annotation 4 VAL A 319
THR A 360
ASP A 304
LEU A 342
 None
None
GOL  A 804 (-2.0A)
None
 1.28A 5m0iB-5n4aA:
undetectable		 5m0iB-5n4aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3f TUBULIN ALPHA-1
CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 VAL A 236
THR A 139
ASN A   8
LEU A 137
 None
 1.34A 5m0iB-5w3fA:
undetectable		 5m0iB-5w3fA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wb0 FUSION GLYCOPROTEIN
F0

(Human
metapneumovirus) 		no annotation 4 VAL F  55
THR F  74
ASP F  72
LEU F  71
 None
 1.29A 5m0iB-5wb0F:
2.2		 5m0iB-5wb0F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wva SHORT-CHAIN
DEHYDROGENASE

(Serratia
marcescens) 		no annotation 4 VAL A  82
ASN A 134
ASP A  89
LEU A  88
 None
 1.05A 5m0iB-5wvaA:
undetectable		 5m0iB-5wvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 VAL A 813
ASN A 657
ASP A 826
LEU A 822
 None
 1.16A 5m0iB-5y7oA:
undetectable		 5m0iB-5y7oA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0u NEOPULLULANASE 1

(Thermoactinomyces
vulgaris) 		no annotation 4 VAL A 231
ASN A 150
ASP A 189
LEU A 190
 None
CA  A 702 (-3.1A)
CA  A 702 (-3.3A)
None
 1.35A 5m0iB-5z0uA:
undetectable		 5m0iB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b1z GLUTAMATE--TRNA
LIGASE

(Elizabethkingia
anophelis) 		PF00749
(tRNA-synt_1c) 		4 THR A 185
ASN A 184
ASP A 168
LEU A 167
 None
 1.32A 5m0iB-6b1zA:
undetectable		 5m0iB-6b1zA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4g ASPARTIC PROTEASE
PM5

(Plasmodium
vivax) 		no annotation 4 VAL A 291
ASN A 300
ASP A 295
LEU A 294
 None
 1.23A 5m0iB-6c4gA:
undetectable		 5m0iB-6c4gA:
undetectable