SIMILAR PATTERNS OF AMINO ACIDS FOR 5LRB_A_ACRA1003_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1btc BETA-AMYLASE

(Glycine max) 		PF01373
(Glyco_hydro_14) 		4 GLU A 306
PHE A 247
THR A 253
TYR A 254
 None
 1.39A 5lrbA-1btcA:
2.3		 5lrbA-1btcA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)

(Enterobacter
cloacae) 		PF13354
(Beta-lactamase2) 		4 PHE A  66
THR A 265
TYR A 264
PHE A  75
 None
 1.26A 5lrbA-1bueA:
undetectable		 5lrbA-1bueA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7t BETA-N-ACETYLHEXOSAM
INIDASE

(Serratia
marcescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF03173
(CHB_HEX)
PF03174
(CHB_HEX_C) 		4 GLU A 380
THR A 740
TYR A 413
PHE A 496
 None
 1.23A 5lrbA-1c7tA:
1.5		 5lrbA-1c7tA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgj ALDEHYDE
OXIDOREDUCTASE

(Desulfovibrio
desulfuricans) 		PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2) 		4 GLU A 552
THR A 467
TYR A 359
TYR A 471
 None
 1.11A 5lrbA-1dgjA:
undetectable		 5lrbA-1dgjA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dy6 CARBAPENEM-HYDROLYSI
NG BETA-LACTAMASE
SME-1

(Serratia
marcescens) 		PF13354
(Beta-lactamase2) 		4 PHE A  66
THR A 265
TYR A 264
PHE A  75
 None
 1.23A 5lrbA-1dy6A:
undetectable		 5lrbA-1dy6A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus scrofa) 		PF00045
(Hemopexin)
PF00413
(Peptidase_M10) 		4 GLU A 418
THR A 409
TYR A 411
PHE A 419
 None
 1.04A 5lrbA-1fblA:
undetectable		 5lrbA-1fblA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gll GLYCEROL KINASE

(Escherichia
coli) 		no annotation 4 PHE Y 365
TYR Y 343
TYR Y 483
PHE Y 421
 None
 1.39A 5lrbA-1gllY:
undetectable		 5lrbA-1gllY:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzh PHOSPHOFRUCTOKINASE

(Borreliella
burgdorferi) 		PF00365
(PFK) 		4 GLU A  37
PHE A  49
THR A  52
TYR A  53
 None
 1.26A 5lrbA-1kzhA:
1.4		 5lrbA-1kzhA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1np7 DNA PHOTOLYASE

(Synechocystis
sp. PCC 6803) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 GLU A 346
THR A 426
TYR A 427
TYR A 248
 None
 1.40A 5lrbA-1np7A:
1.4		 5lrbA-1np7A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa3 ENDO-BETA-1-4-GLUCAN
ASE

(Trichoderma
citrinoviride) 		PF01670
(Glyco_hydro_12) 		4 GLU A 116
PHE A 175
TYR A  60
PHE A 101
 None
 1.42A 5lrbA-1oa3A:
2.3		 5lrbA-1oa3A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p50 ARGININE KINASE

(Limulus
polyphemus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 GLU A 149
PHE A 211
THR A 166
TYR A 167
 None
 1.36A 5lrbA-1p50A:
undetectable		 5lrbA-1p50A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)

(Synechococcus
elongatus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 THR A  26
TYR A  85
TYR A 103
PHE A 364
 None
 1.04A 5lrbA-1rblA:
undetectable		 5lrbA-1rblA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		4 GLU A  89
PHE A  73
THR A 118
TYR A 116
 None
 1.32A 5lrbA-1tfpA:
undetectable		 5lrbA-1tfpA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ark FLAVODOXIN

(Aquifex
aeolicus) 		PF00258
(Flavodoxin_1) 		4 GLU A 147
PHE A  91
THR A  15
PHE A 130
 None
None
PO4  A 501 (-3.2A)
None
 1.42A 5lrbA-2arkA:
undetectable		 5lrbA-2arkA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dqa LYSOZYME

(Ruditapes
philippinarum) 		PF05497
(Destabilase) 		4 GLU A  18
THR A 106
TYR A 109
TYR A  45
 None
 0.92A 5lrbA-2dqaA:
undetectable		 5lrbA-2dqaA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fct SYRINGOMYCIN
BIOSYNTHESIS ENZYME
2

(Pseudomonas
syringae) 		PF05721
(PhyH) 		4 GLU A 102
THR A 120
TYR A 272
PHE A 104
 None
None
None
AKG  A 897 (-3.6A)
 1.21A 5lrbA-2fctA:
undetectable		 5lrbA-2fctA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fq3 TRANSCRIPTION
REGULATORY PROTEIN
SWI3

(Saccharomyces
cerevisiae) 		PF04433
(SWIRM) 		4 GLU A 323
THR A 339
TYR A 343
PHE A 314
 None
 1.09A 5lrbA-2fq3A:
undetectable		 5lrbA-2fq3A:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2igs HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF11508
(DUF3218) 		4 PHE A 119
TYR A 150
TYR A 201
PHE A  50
 None
 1.34A 5lrbA-2igsA:
undetectable		 5lrbA-2igsA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jex REGULATORY PROTEIN
E2

(Deltapapillomavirus
4) 		PF00508
(PPV_E2_N) 		4 GLU A 176
THR A 132
TYR A 131
PHE A 121
 None
 1.40A 5lrbA-2jexA:
undetectable		 5lrbA-2jexA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jex REGULATORY PROTEIN
E2

(Deltapapillomavirus
4) 		PF00508
(PPV_E2_N) 		4 GLU A 176
THR A 132
TYR A 131
PHE A 180
 None
 1.00A 5lrbA-2jexA:
undetectable		 5lrbA-2jexA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)

(Cardiovirus A) 		PF00073
(Rhv) 		4 PHE 3 160
THR 3 161
TYR 3 110
TYR 3 104
 None
 1.31A 5lrbA-2mev3:
undetectable		 5lrbA-2mev3:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4x SEED MATURATION
PROTEIN PM36 HOMOLOG

(Arabidopsis
thaliana) 		PF03070
(TENA_THI-4) 		4 GLU A  88
PHE A  57
TYR A 143
PHE A  92
 HMH  A1300 ( 4.8A)
None
HMH  A1300 (-3.6A)
None
 1.40A 5lrbA-2q4xA:
undetectable		 5lrbA-2q4xA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8w POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
acinosa) 		PF00161
(RIP) 		4 GLU A 175
THR A 124
TYR A 122
TYR A  72
 None
 1.39A 5lrbA-2q8wA:
undetectable		 5lrbA-2q8wA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tpt THYMIDINE
PHOSPHORYLASE

(Escherichia
coli) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 PHE A 167
THR A 170
TYR A 168
PHE A 210
 None
 1.41A 5lrbA-2tptA:
3.2		 5lrbA-2tptA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmh FUCOLECTIN-RELATED
PROTEIN

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		4 GLU A 516
THR A 252
TYR A 275
TYR A  53
 None
None
None
FUC  A1591 (-4.6A)
 1.44A 5lrbA-2wmhA:
undetectable		 5lrbA-2wmhA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wor PROTEIN S100-A7

(Homo sapiens) 		PF01023
(S_100) 		4 GLU A  37
PHE A  16
THR A  20
TYR A  19
 None
 1.17A 5lrbA-2worA:
undetectable		 5lrbA-2worA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdv MYC-INDUCED NUCLEAR
ANTIGEN

(Homo sapiens) 		PF08007
(Cupin_4) 		4 GLU A 146
THR A  75
TYR A  76
PHE A  35
 None
 1.35A 5lrbA-2xdvA:
undetectable		 5lrbA-2xdvA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycb CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR

(Methanothermobacter
thermautotrophicus) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 GLU A 394
THR A 434
TYR A 431
PHE A 576
 None
 1.33A 5lrbA-2ycbA:
undetectable		 5lrbA-2ycbA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayq LYSOZYME

(Meretrix
lusoria) 		PF05497
(Destabilase) 		4 GLU A  18
THR A 105
TYR A 108
TYR A  44
 4NN  A 126 (-2.8A)
None
4NN  A 126 ( 4.9A)
NAG  A 125 (-3.4A)
 1.03A 5lrbA-3ayqA:
undetectable		 5lrbA-3ayqA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d2l SAM-DEPENDENT
METHYLTRANSFERASE

(Exiguobacterium
sibiricum) 		PF13649
(Methyltransf_25) 		4 GLU A 193
THR A  43
TYR A  10
TYR A 108
 None
 1.35A 5lrbA-3d2lA:
2.8		 5lrbA-3d2lA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF14710
(Nitr_red_alph_N) 		4 GLU A 621
THR A 608
TYR A 612
TYR A 548
 None
 1.16A 5lrbA-3egwA:
2.2		 5lrbA-3egwA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehm SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 GLU A  76
PHE A  65
THR A 268
PHE A 487
 None
 1.18A 5lrbA-3ehmA:
undetectable		 5lrbA-3ehmA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejn SUSD HOMOLOG

(Bacteroides
fragilis) 		PF12771
(SusD-like_2) 		4 GLU A 329
PHE A 368
TYR A 371
PHE A 322
 None
 1.25A 5lrbA-3ejnA:
undetectable		 5lrbA-3ejnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY

(Novosphingobium
aromaticivorans) 		PF12680
(SnoaL_2) 		4 GLU A  32
THR A  21
TYR A  22
PHE A 114
 None
 1.34A 5lrbA-3ff2A:
undetectable		 5lrbA-3ff2A:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gt5 N-ACETYLGLUCOSAMINE
2-EPIMERASE

(Xylella
fastidiosa) 		PF07221
(GlcNAc_2-epim) 		4 GLU A 187
THR A 382
TYR A 384
TYR A 120
 None
CL  A 500 (-4.7A)
None
None
 1.14A 5lrbA-3gt5A:
undetectable		 5lrbA-3gt5A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT

(Vibrio
vulnificus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF13588
(HSDR_N_2) 		4 GLU A 112
PHE A 118
THR A 133
TYR A 132
 None
 1.39A 5lrbA-3h1tA:
undetectable		 5lrbA-3h1tA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7l ENDOGLUCANASE

(Vibrio
parahaemolyticus) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 GLU A 280
PHE A 315
THR A 321
TYR A 323
 None
 1.42A 5lrbA-3h7lA:
undetectable		 5lrbA-3h7lA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1
PHENOLOXIDASE
SUBUNIT 2

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 GLU A 171
TYR B  41
TYR B  78
PHE B 465
 None
 1.31A 5lrbA-3hhsA:
undetectable		 5lrbA-3hhsA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwp PHLG

(Pseudomonas
protegens) 		no annotation 4 PHE A  12
THR A  10
TYR A  11
TYR A 265
 None
 1.44A 5lrbA-3hwpA:
undetectable		 5lrbA-3hwpA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwp PHLG

(Pseudomonas
protegens) 		no annotation 4 THR A 183
TYR A 186
TYR A 152
PHE A 216
 None
 1.00A 5lrbA-3hwpA:
undetectable		 5lrbA-3hwpA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Thermus
thermophilus) 		PF01425
(Amidase) 		4 GLU E 113
PHE E  86
THR E  76
PHE E 334
 None
 1.39A 5lrbA-3kfuE:
undetectable		 5lrbA-3kfuE:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o0y LIPOPROTEIN

(Colwellia
psychrerythraea) 		PF05960
(DUF885) 		4 GLU A 344
THR A 330
TYR A 329
PHE A 347
 TRS  A 612 ( 4.5A)
None
TRS  A 612 (-4.1A)
GOL  A 614 (-4.7A)
 1.22A 5lrbA-3o0yA:
undetectable		 5lrbA-3o0yA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8

(Mus musculus) 		PF06920
(DHR-2) 		4 GLU A1939
PHE A1894
THR A1922
PHE A1941
 None
 1.39A 5lrbA-3vhlA:
undetectable		 5lrbA-3vhlA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		4 GLU A 188
THR A 132
TYR A 129
PHE A 189
 None
 1.38A 5lrbA-3wiwA:
undetectable		 5lrbA-3wiwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyx AMINE OXIDASE
[FLAVIN-CONTAINING]
B

(Homo sapiens) 		PF01593
(Amino_oxidase) 		4 GLU A 179
PHE A 402
THR A 400
TYR A 401
 None
 0.98A 5lrbA-3zyxA:
undetectable		 5lrbA-3zyxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0k CULLIN-4A

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 GLU A 450
PHE A 689
THR A 685
PHE A 487
 None
 1.10A 5lrbA-4a0kA:
undetectable		 5lrbA-4a0kA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0l CULLIN-4B

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 GLU E 604
PHE E 843
THR E 839
PHE E 641
 None
 1.29A 5lrbA-4a0lE:
undetectable		 5lrbA-4a0lE:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a6e HYDROXYINDOLE
O-METHYLTRANSFERASE

(Homo sapiens) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 THR A 134
TYR A 131
TYR A 108
PHE A 143
 None
None
ASE  A1350 (-4.9A)
SAM  A1349 (-3.8A)
 1.33A 5lrbA-4a6eA:
undetectable		 5lrbA-4a6eA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bps FKBO

(Streptomyces
hygroscopicus) 		no annotation 4 GLU A  74
THR A 137
TYR A 299
PHE A  24
 None
 1.19A 5lrbA-4bpsA:
undetectable		 5lrbA-4bpsA:
16.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4bqi ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC

(Arabidopsis
thaliana) 		PF00343
(Phosphorylase) 		4 GLU A 576
THR A 619
TYR A 620
PHE A 779
 None
 0.39A 5lrbA-4bqiA:
60.1		 5lrbA-4bqiA:
55.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 2
GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 5

(Saccharomyces
cerevisiae) 		PF04153
(NOT2_3_5) 		4 PHE B 116
THR B 128
TYR C 484
PHE C 472
 None
 1.36A 5lrbA-4by6B:
undetectable		 5lrbA-4by6B:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epz TRANSCRIPTION
ANTI-TERMINATOR
ANTAGONIST UPXZ

(Bacteroides
uniformis) 		PF06603
(UpxZ) 		4 GLU A 117
PHE A 149
THR A 108
TYR A 111
 None
 1.15A 5lrbA-4epzA:
undetectable		 5lrbA-4epzA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ev4 CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1

(Serratia
fonticola) 		PF13354
(Beta-lactamase2) 		4 PHE A  66
THR A 265
TYR A 264
PHE A  75
 None
 1.27A 5lrbA-4ev4A:
undetectable		 5lrbA-4ev4A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f88 PLYCA

(Streptococcus
virus C1) 		PF05257
(CHAP) 		4 GLU 1 113
PHE 1 413
THR 1 415
TYR 1 414
 None
 1.41A 5lrbA-4f881:
undetectable		 5lrbA-4f881:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 GLU B 837
THR B1085
TYR B1083
TYR B 834
 None
 1.10A 5lrbA-4f92B:
undetectable		 5lrbA-4f92B:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft6 PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 GLU A 105
PHE A   3
THR A  48
TYR A  47
 None
 1.37A 5lrbA-4ft6A:
undetectable		 5lrbA-4ft6A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxw ADENOSINE DEAMINASE

(Burkholderia
ambifaria) 		PF00962
(A_deaminase) 		4 GLU A 190
THR A 213
TYR A 242
PHE A 219
 None
 1.07A 5lrbA-4gxwA:
1.8		 5lrbA-4gxwA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6b ALLENE OXIDE CYCLASE

(Physcomitrella
patens) 		PF06351
(Allene_ox_cyc) 		4 GLU A  18
THR A 145
TYR A 144
PHE A  53
 10X  A 201 ( 3.0A)
None
None
10Y  A 202 ( 3.7A)
 1.42A 5lrbA-4h6bA:
undetectable		 5lrbA-4h6bA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4z NAPHTHOATE SYNTHASE

(Synechocystis
sp. PCC 6803) 		PF00378
(ECH_1) 		4 GLU A 252
THR A 244
TYR A 247
PHE A 268
 None
 1.19A 5lrbA-4i4zA:
2.9		 5lrbA-4i4zA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE

(Plasmodium
falciparum) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 GLU A 319
PHE A 574
THR A 576
TYR A 575
 ARG  A1101 (-2.9A)
None
None
ARG  A1101 ( 3.8A)
 1.18A 5lrbA-4j3bA:
undetectable		 5lrbA-4j3bA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN

(Escherichia
virus T5) 		no annotation 4 GLU A  87
THR A   8
TYR A   7
PHE A  89
 None
 1.35A 5lrbA-4jmqA:
undetectable		 5lrbA-4jmqA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyi VIPD

(Legionella
pneumophila) 		PF01734
(Patatin) 		4 GLU A 440
PHE A 413
THR A 412
TYR A  28
 None
 1.44A 5lrbA-4kyiA:
undetectable		 5lrbA-4kyiA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 ARYLPHORIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 PHE B 401
THR B 404
TYR B 402
TYR B 415
 None
None
SCN  B 708 (-4.8A)
None
 1.30A 5lrbA-4l37B:
undetectable		 5lrbA-4l37B:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 SILKWORM STORAGE
PROTEIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 PHE A 398
THR A 401
TYR A 399
TYR A 412
 None
None
SCN  A 709 (-4.6A)
None
 1.29A 5lrbA-4l37A:
undetectable		 5lrbA-4l37A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Pisum sativum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 THR A  26
TYR A  85
TYR A 103
PHE A 364
 None
None
None
PO4  A 502 (-4.8A)
 1.08A 5lrbA-4mkvA:
undetectable		 5lrbA-4mkvA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ook METHIONINE
AMINOPEPTIDASE 2

(Mycobacterium
tuberculosis) 		PF00557
(Peptidase_M24) 		4 GLU A  35
PHE A 100
THR A  94
TYR A  97
 None
 0.97A 5lrbA-4ookA:
undetectable		 5lrbA-4ookA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qan HYPOTHETICAL PROTEIN

([Ruminococcus]
gnavus) 		no annotation 4 GLU A 123
PHE A 117
THR A 110
TYR A 209
 None
 1.44A 5lrbA-4qanA:
undetectable		 5lrbA-4qanA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qme AMINOPEPTIDASE N

(Neisseria
meningitidis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 GLU A 117
PHE A 371
THR A 373
TYR A 372
 37B  A 901 (-2.5A)
None
None
37B  A 901 (-3.5A)
 1.18A 5lrbA-4qmeA:
undetectable		 5lrbA-4qmeA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woe TAUROCYAMINE KINASE

(Schistosoma
mansoni) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 GLU A 509
PHE A 571
THR A 526
TYR A 527
 None
 1.31A 5lrbA-4woeA:
undetectable		 5lrbA-4woeA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 GLU A 121
PHE A 375
THR A 377
TYR A 376
 ARG  A 902 (-3.1A)
None
None
ARG  A 902 ( 3.8A)
 1.21A 5lrbA-4xmvA:
undetectable		 5lrbA-4xmvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BONTOXILYSIN A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 GLU A 154
THR A  51
TYR A 501
TYR A  69
 None
 1.40A 5lrbA-4zktA:
undetectable		 5lrbA-4zktA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8f GENOME POLYPHUMAN
SAFFOLD VIRUS-3 VP3
PROTEIN

(Cardiovirus B) 		PF00073
(Rhv) 		4 PHE B 161
THR B 162
TYR B 111
TYR B 105
 None
 1.26A 5lrbA-5a8fB:
undetectable		 5lrbA-5a8fB:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfc VP3

(Cardiovirus B) 		PF00073
(Rhv) 		4 PHE B 161
THR B 162
TYR B 111
TYR B 105
 None
 1.25A 5lrbA-5cfcB:
undetectable		 5lrbA-5cfcB:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyr RNA-DEPENDENT RNA
POLYMERASE

(Thosea asigna
virus) 		no annotation 4 PHE B 283
THR B 438
TYR B 282
TYR B 270
 None
None
PO4  B 703 (-4.1A)
None
 0.95A 5lrbA-5cyrB:
undetectable		 5lrbA-5cyrB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epd GLYCEROL TRINITRATE
REDUCTASE

(Agrobacterium
tumefaciens) 		PF00724
(Oxidored_FMN) 		4 GLU A 266
PHE A 287
THR A 290
TYR A 291
 None
 1.13A 5lrbA-5epdA:
undetectable		 5lrbA-5epdA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq6 UNCHARACTERIZED
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF12888
(Lipid_bd) 		4 PHE E  26
THR E 132
TYR E 133
TYR E  67
 None
 1.44A 5lrbA-5fq6E:
undetectable		 5lrbA-5fq6E:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)

(Bacteroides
thetaiotaomicron) 		PF16403
(DUF5011)
PF16404
(DUF5012) 		4 GLU G  35
THR G  80
TYR G  69
PHE G  33
 None
 1.40A 5lrbA-5fq8G:
undetectable		 5lrbA-5fq8G:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fva NUCLEOPROTEIN

(Sandfly fever
Naples
phlebovirus) 		PF05733
(Tenui_N) 		4 GLU A 181
THR A 145
TYR A 146
PHE A 182
 None
 1.37A 5lrbA-5fvaA:
undetectable		 5lrbA-5fvaA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g0q BETA-GLUCURONIDASE

(Acidobacterium
capsulatum) 		PF03662
(Glyco_hydro_79n) 		4 PHE A 474
THR A 391
TYR A 314
PHE A 434
 None
 1.40A 5lrbA-5g0qA:
undetectable		 5lrbA-5g0qA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gli ENDOTHELIN RECEPTOR
SUBTYPE-B

(Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 GLU A 236
PHE A 268
THR A 271
TYR A 269
 None
None
OLC  A1206 (-4.8A)
None
 1.23A 5lrbA-5gliA:
undetectable		 5lrbA-5gliA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gli ENDOTHELIN RECEPTOR
SUBTYPE-B

(Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 GLU A 236
PHE A 268
TYR A 269
TYR A 281
 None
 1.29A 5lrbA-5gliA:
undetectable		 5lrbA-5gliA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gm3 ENDOGLUCANASE-1

(Aspergillus
aculeatus) 		PF01670
(Glyco_hydro_12) 		4 GLU A 118
PHE A 177
TYR A  63
PHE A 103
 None
 1.37A 5lrbA-5gm3A:
2.2		 5lrbA-5gm3A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hec PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)

(Streptococcus
parasanguinis) 		PF00535
(Glycos_transf_2) 		4 GLU A  98
PHE A 121
TYR A 214
PHE A 100
 None
 1.43A 5lrbA-5hecA:
2.2		 5lrbA-5hecA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5itq ENDONUCLEASE 8-LIKE
1

(Homo sapiens) 		PF01149
(Fapy_DNA_glyco)
PF06831
(H2TH)
PF09292
(Neil1-DNA_bind) 		4 GLU A  28
PHE A  23
THR A 103
TYR A 102
 None
 1.40A 5lrbA-5itqA:
undetectable		 5lrbA-5itqA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdi PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 8

(Homo sapiens) 		no annotation 4 GLU A 333
PHE A 379
THR A 374
TYR A 372
 None
 1.28A 5lrbA-5kdiA:
undetectable		 5lrbA-5kdiA:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ll7 BETA-LACTAMASE

(Escherichia
coli) 		no annotation 4 PHE A  66
THR A 265
TYR A 264
PHE A  75
 None
 1.34A 5lrbA-5ll7A:
undetectable		 5lrbA-5ll7A:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngw OPGH99A

(Ochrovirga
pacifica) 		no annotation 4 GLU A 341
THR A  56
TYR A  55
TYR A  46
 None
 1.32A 5lrbA-5ngwA:
undetectable		 5lrbA-5ngwA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nur ABC TRANSPORTER
PERMEASE

(Klebsiella
pneumoniae) 		no annotation 4 GLU D 146
PHE D 118
THR D 121
PHE D 141
 None
 1.42A 5lrbA-5nurD:
undetectable		 5lrbA-5nurD:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thk PUTATIVE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF13561
(adh_short_C2) 		4 GLU A 201
TYR A 156
TYR A 208
PHE A 197
 None
 1.28A 5lrbA-5thkA:
4.2		 5lrbA-5thkA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uoh CARBOXYLESTERASE A

(Mycobacterium
tuberculosis) 		PF00561
(Abhydrolase_1) 		4 GLU A 240
THR A 441
TYR A  79
PHE A 241
 None
 1.25A 5lrbA-5uohA:
3.8		 5lrbA-5uohA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5veh KYNURENINE
AMINOTRANSFERASE

(Aedes aegypti) 		no annotation 4 GLU A 320
PHE A 314
TYR A 313
PHE A 409
 None
 1.33A 5lrbA-5vehA:
undetectable		 5lrbA-5vehA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xlu GAMMA GLUTAMYL
TRANSPEPTIDASE

(Bacillus
licheniformis) 		no annotation 4 GLU A 151
PHE A 225
THR A 224
TYR A 237
 GLU  A 151 ( 0.6A)
PHE  A 225 ( 1.3A)
THR  A 224 ( 0.8A)
TYR  A 237 ( 1.3A)
 1.29A 5lrbA-5xluA:
undetectable		 5lrbA-5xluA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yc1 TNF
RECEPTOR-ASSOCIATED
FACTOR 4

(Homo sapiens) 		no annotation 4 GLU A 301
PHE A 337
THR A 339
TYR A 338
 None
 1.24A 5lrbA-5yc1A:
undetectable		 5lrbA-5yc1A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER

(Roseiflexus
castenholzii) 		no annotation 4 THR M 509
TYR M 511
TYR L 204
PHE C 227
 BPH  M 703 ( 4.7A)
None
HEM  C 503 (-4.4A)
None
 1.32A 5lrbA-5yq7M:
undetectable		 5lrbA-5yq7M:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER

(Roseiflexus
castenholzii) 		no annotation 4 THR M 509
TYR M 511
TYR L 208
PHE C 227
 BPH  M 703 ( 4.7A)
None
None
None
 1.26A 5lrbA-5yq7M:
undetectable		 5lrbA-5yq7M:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yvf -

(-) 		no annotation 4 GLU A 204
THR A 166
TYR A 164
PHE A 160
 None
 1.37A 5lrbA-5yvfA:
undetectable		 5lrbA-5yvfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cp7 ATP SYNTHASE SUBUNIT
A
ATP SYNTHASE SUBUNIT
F, MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		no annotation 4 PHE X  29
THR X  33
TYR X  32
PHE U  84
 None
 1.27A 5lrbA-6cp7X:
undetectable		 5lrbA-6cp7X:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d8w HEMAGGLUTININ

(Influenza A
virus) 		no annotation 4 GLU A 245
THR A 213
TYR A 200
TYR A 209
 None
 1.14A 5lrbA-6d8wA:
undetectable		 5lrbA-6d8wA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ehe OMPT PROTEIN

(Vibrio cholerae) 		no annotation 4 GLU A 286
THR A 238
TYR A 248
PHE A 102
 None
 1.14A 5lrbA-6eheA:
undetectable		 5lrbA-6eheA:
7.66