SIMILAR PATTERNS OF AMINO ACIDS FOR 5LJB_A_RTLA201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e19 | CARBAMATE KINASE (Pyrococcusfuriosus) |
PF00696(AA_kinase) | 4 | LEU A 9LEU A 97ILE A 114THR A 112 | None | 0.90A | 5ljbA-1e19A:undetectable | 5ljbA-1e19A:18.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ggl | PROTEIN (CELLULARRETINOL-BINDINGPROTEIN III) (Homo sapiens) |
PF00061(Lipocalin) | 5 | LEU A 20LEU A 36LYS A 40THR A 53TRP A 106 | None | 0.46A | 5ljbA-1gglA:23.1 | 5ljbA-1gglA:54.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h6f | T-BOX TRANSCRIPTIONFACTOR TBX3 (Homo sapiens) |
PF00907(T-box) | 4 | LEU A 107LEU A 112ILE A 259THR A 121 | None | 1.06A | 5ljbA-1h6fA:undetectable | 5ljbA-1h6fA:17.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kqx | CELLULARRETINOL-BINDINGPROTEIN (Danio rerio) |
PF00061(Lipocalin) | 4 | LEU A 36LYS A 40THR A 53GLN A 108 | None | 0.87A | 5ljbA-1kqxA:24.6 | 5ljbA-1kqxA:58.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kqx | CELLULARRETINOL-BINDINGPROTEIN (Danio rerio) |
PF00061(Lipocalin) | 4 | LYS A 40THR A 53TRP A 106GLN A 108 | None | 0.46A | 5ljbA-1kqxA:24.6 | 5ljbA-1kqxA:58.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l6n | GAG POLYPROTEIN (Humanimmunodeficiencyvirus 1) |
PF00540(Gag_p17)PF00607(Gag_p24) | 4 | LEU A 152LEU A 188ILE A 247THR A 180 | None | 0.93A | 5ljbA-1l6nA:undetectable | 5ljbA-1l6nA:20.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lpj | RETINOL-BINDINGPROTEIN IV, CELLULAR (Homo sapiens) |
PF00061(Lipocalin) | 6 | LEU A 36LYS A 40ILE A 51THR A 53TRP A 106MET A 119 | None | 0.56A | 5ljbA-1lpjA:24.4 | 5ljbA-1lpjA:56.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mx8 | CELLULARRETINOL-BINDINGPROTEIN I, HOLO (Rattusnorvegicus) |
PF00061(Lipocalin) | 4 | LEU A 20LEU A 36LYS A 40ILE A 51 | RTL A 135 ( 4.7A)RTL A 135 ( 4.6A)RTL A 135 ( 4.4A)RTL A 135 ( 4.6A) | 0.85A | 5ljbA-1mx8A:19.7 | 5ljbA-1mx8A:96.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ps9 | 2,4-DIENOYL-COAREDUCTASE (Escherichiacoli) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 4 | LEU A 537LEU A 275ILE A 289THR A 285 | None | 0.93A | 5ljbA-1ps9A:undetectable | 5ljbA-1ps9A:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tzx | N UTILIZATIONSUBSTANCE PROTEIN BHOMOLOG (Thermotogamaritima) |
PF01029(NusB) | 4 | LEU A 64LEU A 85ILE A 98THR A 103 | None | 1.06A | 5ljbA-1tzxA:undetectable | 5ljbA-1tzxA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1w | STRUCTURALMAINTENANCE OFCHROMOSOME 1SISTER CHROMATIDCOHESION PROTEIN 1 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF02463(SMC_N)PF04824(Rad21_Rec8) | 4 | LEU E 532LEU A1218ILE A1186THR A 29 | None | 1.07A | 5ljbA-1w1wE:undetectable | 5ljbA-1w1wE:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa5 | IMPORTIN ALPHARE-EXPORTER (Saccharomycescerevisiae) |
PF03378(CAS_CSE1)PF03810(IBN_N)PF08506(Cse1) | 4 | LEU C 240LEU C 269ILE C 322THR C 274 | None | 0.96A | 5ljbA-1wa5C:undetectable | 5ljbA-1wa5C:7.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1we1 | HEME OXYGENASE 1 (Synechocystissp. PCC 6803) |
PF01126(Heme_oxygenase) | 4 | LEU A 74LEU A 129ILE A 65MET A 57 | NoneHEM A 300 ( 4.4A)NoneIPA A1005 (-4.8A) | 1.01A | 5ljbA-1we1A:undetectable | 5ljbA-1we1A:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xup | GLYCEROL KINASE (Enterococcuscasseliflavus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | LEU O 146LEU O 162ILE O 53GLN O 83 | None | 0.87A | 5ljbA-1xupO:undetectable | 5ljbA-1xupO:13.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8p | [PYRUVATEDEHYDROGENASE[LIPOAMIDE]] KINASEISOZYME 3 (Homo sapiens) |
PF02518(HATPase_c)PF10436(BCDHK_Adom3) | 4 | LEU A 72LEU A 66THR A 60MET A 126 | None | 1.02A | 5ljbA-1y8pA:undetectable | 5ljbA-1y8pA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yve | ACETOHYDROXY ACIDISOMEROREDUCTASE (Spinaciaoleracea) |
PF01450(IlvC)PF07991(IlvN) | 4 | LEU I 118LEU I 298ILE I 107THR I 303 | None | 1.05A | 5ljbA-1yveI:undetectable | 5ljbA-1yveI:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8g | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 4 | LEU A 49LEU A 6ILE A 117THR A 95 | None | 1.04A | 5ljbA-2a8gA:3.2 | 5ljbA-2a8gA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akp | ATP-DEPENDENTMOLECULAR CHAPERONEHSP82 (Saccharomycescerevisiae) |
PF00183(HSP90)PF02518(HATPase_c) | 4 | LEU A 127LEU A 75ILE A 167GLN A 145 | None | 1.03A | 5ljbA-2akpA:undetectable | 5ljbA-2akpA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4i | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 4 | LEU A 128LEU A 85ILE A 62THR A 40 | None | 0.98A | 5ljbA-2c4iA:undetectable | 5ljbA-2c4iA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4i | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 4 | LEU A 249LEU A 206ILE A 183THR A 161 | None | 0.98A | 5ljbA-2c4iA:undetectable | 5ljbA-2c4iA:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2cbr | PROTEIN (CRABP-I) (Bos taurus) |
PF00061(Lipocalin) | 4 | LEU A 19ILE A 63THR A 61TRP A 109 | None | 0.99A | 5ljbA-2cbrA:20.2 | 5ljbA-2cbrA:41.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h1i | CARBOXYLESTERASE (Bacillus cereus) |
PF02230(Abhydrolase_2) | 4 | LEU A 125LEU A 20ILE A 73THR A 76 | None | 1.06A | 5ljbA-2h1iA:undetectable | 5ljbA-2h1iA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6j | SULFOLOBUSSOLFATARICUS PROTEINTYROSINE PHOSPHATASE (Sulfolobussolfataricus) |
PF00102(Y_phosphatase) | 4 | LEU A 55LEU A 93ILE A 67GLN A 77 | None | 0.94A | 5ljbA-2i6jA:undetectable | 5ljbA-2i6jA:25.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j4r | EXOPOLYPHOSPHATASE (Aquifexaeolicus) |
PF02541(Ppx-GppA) | 4 | LEU A 290LEU A 209ILE A 165THR A 147 | None | 1.05A | 5ljbA-2j4rA:undetectable | 5ljbA-2j4rA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j5t | GLUTAMATE 5-KINASE (Escherichiacoli) |
PF00696(AA_kinase)PF01472(PUA) | 4 | LEU A 166ILE A 188THR A 253MET A 214 | None | 0.89A | 5ljbA-2j5tA:undetectable | 5ljbA-2j5tA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgs | CIRCULAR PERMUTANTOF AVIDIN (Gallus gallus) |
PF01382(Avidin) | 4 | LEU A 7LEU A 98ILE A 75THR A 53 | None | 1.05A | 5ljbA-2jgsA:3.0 | 5ljbA-2jgsA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kdy | FACTOR H BINDINGPROTEIN VARIANTB01_001 (Neisseriameningitidis) |
PF08794(Lipoprot_C) | 4 | LEU A 52LEU A 69ILE A 137THR A 113 | None | 1.03A | 5ljbA-2kdyA:2.0 | 5ljbA-2kdyA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o62 | HYPOTHETICAL PROTEIN (Nostocpunctiforme) |
PF12204(DUF3598) | 4 | LEU A 167LEU A 239ILE A 198GLN A 210 | GOL A 274 (-4.7A)NoneNoneGOL A 277 (-3.2A) | 0.99A | 5ljbA-2o62A:8.2 | 5ljbA-2o62A:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsx | PUTATIVETRANSCRIPTIONALREGULATOR, LYSRFAMILY (Vibrioparahaemolyticus) |
PF03466(LysR_substrate) | 4 | LEU A 211LEU A 31THR A 23GLN A 112 | NoneNoneSO4 A 216 ( 3.2A)SO4 A 216 ( 4.4A) | 1.03A | 5ljbA-2qsxA:undetectable | 5ljbA-2qsxA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2quq | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITB (Saccharomycescerevisiae) |
PF16846(Cep3) | 4 | LEU A 162LEU A 238ILE A 284THR A 288 | None | 0.98A | 5ljbA-2quqA:undetectable | 5ljbA-2quqA:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qve | TYROSINE AMINOMUTASE (Streptomycesglobisporus) |
PF00221(Lyase_aromatic) | 4 | LEU A 527LEU A 222ILE A 313GLN A 382 | None | 0.97A | 5ljbA-2qveA:undetectable | 5ljbA-2qveA:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r41 | UNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF06124(DUF960) | 4 | LEU A 75LEU A 31ILE A 41GLN A 64 | None | 1.04A | 5ljbA-2r41A:undetectable | 5ljbA-2r41A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5v | PCZA361.1 (Amycolatopsisorientalis) |
PF00903(Glyoxalase)PF14696(Glyoxalase_5) | 4 | LEU A 303ILE A 216THR A 214GLN A 240 | NoneNoneHHH A4114 (-3.1A)None | 0.97A | 5ljbA-2r5vA:undetectable | 5ljbA-2r5vA:15.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rcq | RETINOL-BINDINGPROTEIN II, CELLULAR (Homo sapiens) |
PF00061(Lipocalin) | 4 | LYS A 40THR A 53TRP A 106GLN A 108 | None | 0.59A | 5ljbA-2rcqA:23.9 | 5ljbA-2rcqA:53.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rhz | LETHAL(3)MALIGNANTBRAIN TUMOR-LIKEPROTEIN (Homo sapiens) |
PF02820(MBT) | 4 | LEU A 240LYS A 243ILE A 257THR A 259 | None | 0.84A | 5ljbA-2rhzA:undetectable | 5ljbA-2rhzA:16.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rin | PUTATIVE GLYCINEBETAINE-BINDING ABCTRANSPORTER PROTEIN (Sinorhizobiummeliloti) |
PF04069(OpuAC) | 4 | LEU A 297LEU A 57ILE A 267THR A 52 | None | 0.95A | 5ljbA-2rinA:undetectable | 5ljbA-2rinA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w21 | GLUTAMATE 5-KINASE (Escherichiacoli) |
PF00696(AA_kinase) | 4 | LEU A 166ILE A 188THR A 253MET A 214 | None | 0.92A | 5ljbA-2w21A:undetectable | 5ljbA-2w21A:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zj4 | GLUCOSAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] 1 (Homo sapiens) |
PF01380(SIS) | 4 | LEU A 529LYS A 635ILE A 627THR A 633 | None | 1.05A | 5ljbA-2zj4A:undetectable | 5ljbA-2zj4A:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b5o | CADD-LIKE PROTEIN OFUNKNOWN FUNCTION (Nostocpunctiforme) |
PF12981(DUF3865) | 4 | LEU A 171LEU A 152ILE A 49GLN A 46 | None | 1.05A | 5ljbA-3b5oA:undetectable | 5ljbA-3b5oA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5t | MALATE DEHYDROGENASE (Burkholderiapseudomallei) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 117LEU A 86ILE A 71GLN A 48 | None | 1.01A | 5ljbA-3d5tA:undetectable | 5ljbA-3d5tA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fr8 | PUTATIVE KETOL-ACIDREDUCTOISOMERASE(OS05G0573700PROTEIN) (Oryza sativa) |
PF01450(IlvC)PF07991(IlvN) | 4 | LEU A 118LEU A 298ILE A 107THR A 303 | None | 0.99A | 5ljbA-3fr8A:undetectable | 5ljbA-3fr8A:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnr | OS03G0212800 PROTEIN (Oryza sativa) |
PF00232(Glyco_hydro_1) | 4 | LEU A 201LEU A 342ILE A 333THR A 331 | LEU A 201 ( 0.6A)LEU A 342 ( 0.5A)ILE A 333 ( 0.4A)THR A 331 ( 0.8A) | 0.93A | 5ljbA-3gnrA:undetectable | 5ljbA-3gnrA:15.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hka | URONATE ISOMERASE (Bacillushalodurans) |
no annotation | 4 | LEU A 51LEU A 97ILE A 334GLN A 352 | None | 1.00A | 5ljbA-3hkaA:undetectable | 5ljbA-3hkaA:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kgw | ALANINE-GLYOXYLATEAMINOTRANSFERASE (Mus musculus) |
PF00266(Aminotran_5) | 4 | LEU A 115LEU A 96ILE A 215GLN A 220 | NoneNoneNoneEDO A 507 ( 4.7A) | 1.01A | 5ljbA-3kgwA:undetectable | 5ljbA-3kgwA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pmm | PUTATIVE CYTOPLASMICPROTEIN (Klebsiellapneumoniae) |
PF07470(Glyco_hydro_88) | 4 | LEU A 375LEU A 27ILE A 89THR A 32 | NoneNoneNoneFMT A 387 ( 4.5A) | 1.01A | 5ljbA-3pmmA:undetectable | 5ljbA-3pmmA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qwt | PUTATIVE GH105FAMILY PROTEIN (Salmonellaenterica) |
PF07470(Glyco_hydro_88) | 4 | LEU A 168ILE A 301THR A 235TRP A 278 | None | 1.07A | 5ljbA-3qwtA:undetectable | 5ljbA-3qwtA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qwt | PUTATIVE GH105FAMILY PROTEIN (Salmonellaenterica) |
PF07470(Glyco_hydro_88) | 4 | LEU A 374LEU A 26ILE A 88THR A 31 | None | 0.98A | 5ljbA-3qwtA:undetectable | 5ljbA-3qwtA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rmj | 2-ISOPROPYLMALATESYNTHASE (Neisseriameningitidis) |
PF00682(HMGL-like) | 4 | LEU A 259LEU A 217ILE A 170TRP A 201 | None | 1.02A | 5ljbA-3rmjA:undetectable | 5ljbA-3rmjA:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tc3 | UV DAMAGEENDONUCLEASE (Sulfolobusacidocaldarius) |
PF03851(UvdE) | 4 | LEU A 45ILE A 63THR A 62MET A 132 | None | 1.05A | 5ljbA-3tc3A:undetectable | 5ljbA-3tc3A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttg | PUTATIVEAMINOMETHYLTRANSFERASE (Leptospirillumrubarum) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | LEU A 227LEU A 211ILE A 288THR A 290 | NoneNone CL A 336 ( 4.6A)None | 0.90A | 5ljbA-3ttgA:undetectable | 5ljbA-3ttgA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3up4 | OTEMO (Pseudomonasputida) |
PF00743(FMO-like) | 4 | LEU A 146ILE A 200THR A 196TRP A 170 | NAP A 552 (-4.2A)NoneNAP A 552 (-3.5A)None | 1.04A | 5ljbA-3up4A:undetectable | 5ljbA-3up4A:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zgj | 4-HYDROXYPHENYLPYRUVIC ACID DIOXYGENASE (Streptomycescoelicolor) |
PF00903(Glyoxalase)PF14696(Glyoxalase_5) | 4 | LEU A 323ILE A 236THR A 234GLN A 260 | NoneRMN A1369 ( 4.8A)RMN A1369 (-3.2A)RMN A1369 ( 4.7A) | 0.98A | 5ljbA-3zgjA:undetectable | 5ljbA-3zgjA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4l | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3 (Homo sapiens) |
PF00300(His_Phos_1)PF01591(6PF2K) | 4 | LEU A 369LEU A 391ILE A 304THR A 303 | None | 0.99A | 5ljbA-4d4lA:undetectable | 5ljbA-4d4lA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dd5 | ACETYL-COAACETYLTRANSFERASE (Clostridioidesdifficile) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | LEU A 183ILE A 292TRP A 173GLN A 172 | None | 0.94A | 5ljbA-4dd5A:undetectable | 5ljbA-4dd5A:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkv | ALCOHOLDEHYDROGENASE,PROPANOL-PREFERRING (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 311LEU A 56ILE A 122MET A 1 | None | 1.07A | 5ljbA-4gkvA:undetectable | 5ljbA-4gkvA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h6y | FERM, RHOGEF ANDPLECKSTRINDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00169(PH)PF00621(RhoGEF) | 4 | LEU A 606LEU A 599THR A 551GLN A 694 | None | 1.04A | 5ljbA-4h6yA:undetectable | 5ljbA-4h6yA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 4 | LEU M 285LEU M 361ILE M 78THR M 81 | None | 0.98A | 5ljbA-4heaM:undetectable | 5ljbA-4heaM:13.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4i9r | CELLULAR RETINOICACID-BINDING PROTEIN2 (Homo sapiens) |
PF00061(Lipocalin) | 4 | LEU A 19ILE A 63TRP A 109MET A 123 | NoneRET A 201 ( 4.7A)RET A 201 (-3.7A)RET A 201 (-4.6A) | 1.00A | 5ljbA-4i9rA:19.5 | 5ljbA-4i9rA:43.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ict | CYTOCHROME P450 121 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | LEU A 124LEU A 362ILE A 388THR A 243 | None | 0.95A | 5ljbA-4ictA:undetectable | 5ljbA-4ictA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il5 | CYSTEINE SYNTHASE (Entamoebahistolytica) |
PF00291(PALP) | 4 | LEU A 331ILE A 321TRP A 263GLN A 260 | None | 0.99A | 5ljbA-4il5A:undetectable | 5ljbA-4il5A:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k17 | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 16A (Mus musculus) |
PF13516(LRR_6) | 4 | LEU A 386LEU A 379THR A 375MET A 357 | None | 0.81A | 5ljbA-4k17A:undetectable | 5ljbA-4k17A:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 4 | LEU A 50LEU A 153ILE A 38THR A 41 | None | 1.05A | 5ljbA-4mwzA:undetectable | 5ljbA-4mwzA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n7t | PHOSPHOPENTOMUTASE (Streptococcusmutans) |
PF01676(Metalloenzyme) | 4 | LEU A 9LEU A 83ILE A 104TRP A 97 | None | 1.00A | 5ljbA-4n7tA:undetectable | 5ljbA-4n7tA:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pbv | NT-3 GROWTH FACTORRECEPTORPROTEIN-TYROSINEPHOSPHATASECRYPALPHA1 ISOFORM (Gallus gallus;Gallus gallus) |
PF00047(ig)PF13855(LRR_8)PF16920(TPKR_C2)PF07679(I-set)PF13927(Ig_3) | 4 | LEU A 139LEU A 94TRP A 144GLN C 75 | None | 0.73A | 5ljbA-4pbvA:undetectable | 5ljbA-4pbvA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q73 | PROLINEDEHYDROGENASE (Bradyrhizobiumdiazoefficiens) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 4 | LEU A 458LEU A 67ILE A 922THR A 139 | None | 1.06A | 5ljbA-4q73A:undetectable | 5ljbA-4q73A:8.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r85 | CYTOSINE DEAMINASE (Klebsiellapneumoniae) |
PF07969(Amidohydro_3) | 4 | LEU A 144LEU A 100ILE A 90THR A 95 | None | 0.98A | 5ljbA-4r85A:undetectable | 5ljbA-4r85A:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgy | ESTERASE (unculturedbacterium FLS12) |
PF00756(Esterase) | 5 | LEU A 193LEU A 134ILE A 176THR A 86GLN A 173 | None | 1.45A | 5ljbA-4rgyA:undetectable | 5ljbA-4rgyA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ryk | LMO0325 PROTEIN (Listeriamonocytogenes) |
PF01381(HTH_3) | 4 | LEU A 181LEU A 200ILE A 250GLN A 247 | None | 1.04A | 5ljbA-4rykA:undetectable | 5ljbA-4rykA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ryk | LMO0325 PROTEIN (Listeriamonocytogenes) |
PF01381(HTH_3) | 4 | LEU A 181LEU A 200THR A 205GLN A 247 | None | 0.99A | 5ljbA-4rykA:undetectable | 5ljbA-4rykA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s0h | T-BOX TRANSCRIPTIONFACTOR TBX5 (Homo sapiens) |
PF00907(T-box) | 4 | LEU A 58LEU A 63ILE A 212THR A 72 | None | 1.05A | 5ljbA-4s0hA:undetectable | 5ljbA-4s0hA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4trk | C. ELEGANS HIM-3 (Caenorhabditiselegans) |
PF02301(HORMA) | 4 | LEU A 182LEU A 51ILE A 225MET A 179 | None | 0.89A | 5ljbA-4trkA:undetectable | 5ljbA-4trkA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgc | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 4ORIGIN RECOGNITIONCOMPLEX SUBUNIT 5 (Drosophilamelanogaster;Drosophilamelanogaster) |
PF13191(AAA_16)PF14629(ORC4_C)PF13191(AAA_16)PF14630(ORC5_C) | 4 | LEU E 102LEU E 148ILE D 85GLN D 245 | None | 1.04A | 5ljbA-4xgcE:undetectable | 5ljbA-4xgcE:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwh | ALPHA-N-ACETYLGLUCOSAMINIDASE (Homo sapiens) |
PF05089(NAGLU)PF12971(NAGLU_N)PF12972(NAGLU_C) | 4 | LEU A 622LEU A 666ILE A 448TRP A 145 | None | 1.04A | 5ljbA-4xwhA:undetectable | 5ljbA-4xwhA:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwj | CHIMERA PROTEIN OFHUMAN RHODOPSIN,MOUSE S-ARRESTIN,AND T4 ENDOLYSIN (Homo sapiens;Mus musculus;Escherichiavirus T4) |
PF00001(7tm_1)PF00339(Arrestin_N)PF00959(Phage_lysozyme)PF02752(Arrestin_C)PF10413(Rhodopsin_N) | 4 | LEU A 47ILE A 286THR A 289GLN A 36 | None | 1.06A | 5ljbA-4zwjA:undetectable | 5ljbA-4zwjA:10.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzh | NAD-DEPENDENTPROTEIN DEACETYLASESIRTUIN-1 (Homo sapiens) |
PF02146(SIR2) | 4 | LEU A 228LEU A 202ILE A 194THR A 196 | None | 0.96A | 5ljbA-4zzhA:undetectable | 5ljbA-4zzhA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ajz | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3 (Homo sapiens) |
PF00300(His_Phos_1)PF01591(6PF2K) | 4 | LEU A 369LEU A 391ILE A 304THR A 303 | None | 0.98A | 5ljbA-5ajzA:undetectable | 5ljbA-5ajzA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aor | DOSAGE COMPENSATIONREGULATOR (Drosophilamelanogaster) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 4 | LEU A 665ILE A 719THR A 717GLN A 699 | None U C 7 ( 3.9A) U C 7 ( 2.9A)None | 0.89A | 5ljbA-5aorA:undetectable | 5ljbA-5aorA:7.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 4 | LEU A 171LEU A 178ILE A 116THR A 123 | NoneNoneSAH A 301 ( 4.6A)None | 1.00A | 5ljbA-5bp7A:undetectable | 5ljbA-5bp7A:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bq2 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00275(EPSP_synthase) | 4 | LEU A 4LEU A 384ILE A 236THR A 240 | None | 0.95A | 5ljbA-5bq2A:undetectable | 5ljbA-5bq2A:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6g | AGR133CPSISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii;Eremotheciumgossypii) |
PF10345(Cohesin_load)no annotation | 4 | LEU B 19LEU A 584GLN A 609MET A 612 | None | 0.95A | 5ljbA-5c6gB:undetectable | 5ljbA-5c6gB:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cgz | 4-OXALMESACONATEHYDRATASE (Pseudomonasputida) |
PF02585(PIG-L) | 4 | LEU A 115LEU A 177ILE A 190TRP A 20 | None | 1.06A | 5ljbA-5cgzA:undetectable | 5ljbA-5cgzA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hee | PUTATIVEUNCHARACTERIZEDPROTEIN, TK2203PROTEIN (Thermococcuskodakarensis) |
PF02900(LigB) | 4 | LEU A 64LEU A 44ILE A 52THR A 137 | None | 0.96A | 5ljbA-5heeA:undetectable | 5ljbA-5heeA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxa | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Paraburkholderiaxenovorans) |
PF00982(Glyco_transf_20) | 4 | LEU A 302LEU A 279THR A 367GLN A 417 | None | 0.81A | 5ljbA-5hxaA:undetectable | 5ljbA-5hxaA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hyh | UNCHARACTERIZEDPROTEIN (Streptomycesvenezuelae) |
PF11583(AurF) | 4 | LEU A 195ILE A 206THR A 202MET A 323 | None | 0.98A | 5ljbA-5hyhA:undetectable | 5ljbA-5hyhA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja1 | ENTEROBACTINSYNTHASE COMPONENT F (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 4 | LEU A1088LEU A1135ILE A1057GLN A1126 | None | 0.94A | 5ljbA-5ja1A:undetectable | 5ljbA-5ja1A:7.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1s | OXIDOREDUCTASE,ZINC-BINDINGDEHYDROGENASE FAMILY (Myxococcusxanthus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 117ILE A 69GLN A -2MET A 1 | None | 1.01A | 5ljbA-5k1sA:undetectable | 5ljbA-5k1sA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kc9 | GLUTAMATE RECEPTORIONOTROPIC, DELTA-1 (Mus musculus) |
PF01094(ANF_receptor) | 4 | LEU A 270LEU A 231ILE A 318GLN A 283 | BU1 A 520 (-4.1A)NoneNoneNone | 1.04A | 5ljbA-5kc9A:undetectable | 5ljbA-5kc9A:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) |
PF03321(GH3) | 4 | LEU A 250LEU A 259ILE A 202THR A 201 | None | 1.03A | 5ljbA-5kodA:undetectable | 5ljbA-5kodA:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldr | BETA-D-GALACTOSIDASE (Paracoccus sp.32d) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 4 | LEU B 254LEU B 166ILE B 160THR B 162 | NoneNoneNone CL B 806 ( 4.7A) | 1.05A | 5ljbA-5ldrB:undetectable | 5ljbA-5ldrB:10.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nn7 | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus8) |
no annotation | 4 | LEU A 41ILE A 52GLN A 65MET A 69 | None | 0.68A | 5ljbA-5nn7A:undetectable | 5ljbA-5nn7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nn7 | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus8) |
no annotation | 4 | LEU A 217LEU A 214ILE A 115TRP A 187 | None | 0.92A | 5ljbA-5nn7A:undetectable | 5ljbA-5nn7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | RIBOSOMAL PROTEINS19, PUTATIVE (Trypanosomacruzi) |
no annotation | 4 | LEU o 127LEU o 117ILE o 108GLN o 65 | None | 0.92A | 5ljbA-5opto:undetectable | 5ljbA-5opto:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr0 | SEED LINOLEATE13S-LIPOXYGENASE-1 (Glycine max) |
no annotation | 4 | LEU A 546LEU A 496ILE A 704THR A 709 | None | 1.04A | 5ljbA-5tr0A:undetectable | 5ljbA-5tr0A:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5van | BETA-KLOTHO (Homo sapiens) |
no annotation | 4 | LEU A 814LEU A 721ILE A 689THR A 690 | None | 1.04A | 5ljbA-5vanA:undetectable | 5ljbA-5vanA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xap | PROTEIN TRANSLOCASESUBUNIT SECD (Deinococcusradiodurans) |
PF02355(SecD_SecF)PF07549(Sec_GG) | 4 | LEU A 76ILE A 430THR A 427MET A 70 | None | 1.00A | 5ljbA-5xapA:undetectable | 5ljbA-5xapA:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xh9 | EXTRACELLULARINVERTASE (Aspergilluskawachii) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | LEU A 393LEU A 82ILE A 293THR A 272 | None | 1.06A | 5ljbA-5xh9A:undetectable | 5ljbA-5xh9A:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y58 | ATP-DEPENDENT DNAHELICASE II SUBUNIT1ATP-DEPENDENT DNAHELICASE II SUBUNIT2 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
no annotationno annotation | 4 | LEU A 432LEU A 405ILE B 585THR A 400 | None | 1.06A | 5ljbA-5y58A:undetectable | 5ljbA-5y58A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cip | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Moorellathermoacetica) |
no annotation | 4 | LEU A 325LEU A 297ILE A 407THR A 284 | None | 0.97A | 5ljbA-6cipA:undetectable | 5ljbA-6cipA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cn1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Pseudomonasputida) |
no annotation | 4 | LEU A 4LEU A 384ILE A 236THR A 240 | None | 1.03A | 5ljbA-6cn1A:undetectable | 5ljbA-6cn1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ez8 | HUNTINGTIN (Homo sapiens) |
no annotation | 4 | LEU A1293LEU A1142ILE A1087GLN A1083 | None | 0.98A | 5ljbA-6ez8A:undetectable | 5ljbA-6ez8A:undetectable |