SIMILAR PATTERNS OF AMINO ACIDS FOR 5LJB_A_RTLA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e19 CARBAMATE KINASE

(Pyrococcus
furiosus)
PF00696
(AA_kinase)
4 LEU A   9
LEU A  97
ILE A 114
THR A 112
None
0.90A 5ljbA-1e19A:
undetectable
5ljbA-1e19A:
18.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggl PROTEIN (CELLULAR
RETINOL-BINDING
PROTEIN III)


(Homo sapiens)
PF00061
(Lipocalin)
5 LEU A  20
LEU A  36
LYS A  40
THR A  53
TRP A 106
None
0.46A 5ljbA-1gglA:
23.1
5ljbA-1gglA:
54.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6f T-BOX TRANSCRIPTION
FACTOR TBX3


(Homo sapiens)
PF00907
(T-box)
4 LEU A 107
LEU A 112
ILE A 259
THR A 121
None
1.06A 5ljbA-1h6fA:
undetectable
5ljbA-1h6fA:
17.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kqx CELLULAR
RETINOL-BINDING
PROTEIN


(Danio rerio)
PF00061
(Lipocalin)
4 LEU A  36
LYS A  40
THR A  53
GLN A 108
None
0.87A 5ljbA-1kqxA:
24.6
5ljbA-1kqxA:
58.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kqx CELLULAR
RETINOL-BINDING
PROTEIN


(Danio rerio)
PF00061
(Lipocalin)
4 LYS A  40
THR A  53
TRP A 106
GLN A 108
None
0.46A 5ljbA-1kqxA:
24.6
5ljbA-1kqxA:
58.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l6n GAG POLYPROTEIN

(Human
immunodeficiency
virus 1)
PF00540
(Gag_p17)
PF00607
(Gag_p24)
4 LEU A 152
LEU A 188
ILE A 247
THR A 180
None
0.93A 5ljbA-1l6nA:
undetectable
5ljbA-1l6nA:
20.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lpj RETINOL-BINDING
PROTEIN IV, CELLULAR


(Homo sapiens)
PF00061
(Lipocalin)
6 LEU A  36
LYS A  40
ILE A  51
THR A  53
TRP A 106
MET A 119
None
0.56A 5ljbA-1lpjA:
24.4
5ljbA-1lpjA:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO


(Rattus
norvegicus)
PF00061
(Lipocalin)
4 LEU A  20
LEU A  36
LYS A  40
ILE A  51
RTL  A 135 ( 4.7A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
0.85A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ps9 2,4-DIENOYL-COA
REDUCTASE


(Escherichia
coli)
PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2)
4 LEU A 537
LEU A 275
ILE A 289
THR A 285
None
0.93A 5ljbA-1ps9A:
undetectable
5ljbA-1ps9A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tzx N UTILIZATION
SUBSTANCE PROTEIN B
HOMOLOG


(Thermotoga
maritima)
PF01029
(NusB)
4 LEU A  64
LEU A  85
ILE A  98
THR A 103
None
1.06A 5ljbA-1tzxA:
undetectable
5ljbA-1tzxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1w STRUCTURAL
MAINTENANCE OF
CHROMOSOME 1
SISTER CHROMATID
COHESION PROTEIN 1


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF02463
(SMC_N)
PF04824
(Rad21_Rec8)
4 LEU E 532
LEU A1218
ILE A1186
THR A  29
None
1.07A 5ljbA-1w1wE:
undetectable
5ljbA-1w1wE:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
RE-EXPORTER


(Saccharomyces
cerevisiae)
PF03378
(CAS_CSE1)
PF03810
(IBN_N)
PF08506
(Cse1)
4 LEU C 240
LEU C 269
ILE C 322
THR C 274
None
0.96A 5ljbA-1wa5C:
undetectable
5ljbA-1wa5C:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1we1 HEME OXYGENASE 1

(Synechocystis
sp. PCC 6803)
PF01126
(Heme_oxygenase)
4 LEU A  74
LEU A 129
ILE A  65
MET A  57
None
HEM  A 300 ( 4.4A)
None
IPA  A1005 (-4.8A)
1.01A 5ljbA-1we1A:
undetectable
5ljbA-1we1A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xup GLYCEROL KINASE

(Enterococcus
casseliflavus)
PF00370
(FGGY_N)
PF02782
(FGGY_C)
4 LEU O 146
LEU O 162
ILE O  53
GLN O  83
None
0.87A 5ljbA-1xupO:
undetectable
5ljbA-1xupO:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8p [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 3


(Homo sapiens)
PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3)
4 LEU A  72
LEU A  66
THR A  60
MET A 126
None
1.02A 5ljbA-1y8pA:
undetectable
5ljbA-1y8pA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yve ACETOHYDROXY ACID
ISOMEROREDUCTASE


(Spinacia
oleracea)
PF01450
(IlvC)
PF07991
(IlvN)
4 LEU I 118
LEU I 298
ILE I 107
THR I 303
None
1.05A 5ljbA-1yveI:
undetectable
5ljbA-1yveI:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8g AVIDIN

(Gallus gallus)
PF01382
(Avidin)
4 LEU A  49
LEU A   6
ILE A 117
THR A  95
None
1.04A 5ljbA-2a8gA:
3.2
5ljbA-2a8gA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2akp ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82


(Saccharomyces
cerevisiae)
PF00183
(HSP90)
PF02518
(HATPase_c)
4 LEU A 127
LEU A  75
ILE A 167
GLN A 145
None
1.03A 5ljbA-2akpA:
undetectable
5ljbA-2akpA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4i AVIDIN

(Gallus gallus)
PF01382
(Avidin)
4 LEU A 128
LEU A  85
ILE A  62
THR A  40
None
0.98A 5ljbA-2c4iA:
undetectable
5ljbA-2c4iA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4i AVIDIN

(Gallus gallus)
PF01382
(Avidin)
4 LEU A 249
LEU A 206
ILE A 183
THR A 161
None
0.98A 5ljbA-2c4iA:
undetectable
5ljbA-2c4iA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2cbr PROTEIN (CRABP-I)

(Bos taurus)
PF00061
(Lipocalin)
4 LEU A  19
ILE A  63
THR A  61
TRP A 109
None
0.99A 5ljbA-2cbrA:
20.2
5ljbA-2cbrA:
41.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1i CARBOXYLESTERASE

(Bacillus cereus)
PF02230
(Abhydrolase_2)
4 LEU A 125
LEU A  20
ILE A  73
THR A  76
None
1.06A 5ljbA-2h1iA:
undetectable
5ljbA-2h1iA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6j SULFOLOBUS
SOLFATARICUS PROTEIN
TYROSINE PHOSPHATASE


(Sulfolobus
solfataricus)
PF00102
(Y_phosphatase)
4 LEU A  55
LEU A  93
ILE A  67
GLN A  77
None
0.94A 5ljbA-2i6jA:
undetectable
5ljbA-2i6jA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4r EXOPOLYPHOSPHATASE

(Aquifex
aeolicus)
PF02541
(Ppx-GppA)
4 LEU A 290
LEU A 209
ILE A 165
THR A 147
None
1.05A 5ljbA-2j4rA:
undetectable
5ljbA-2j4rA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5t GLUTAMATE 5-KINASE

(Escherichia
coli)
PF00696
(AA_kinase)
PF01472
(PUA)
4 LEU A 166
ILE A 188
THR A 253
MET A 214
None
0.89A 5ljbA-2j5tA:
undetectable
5ljbA-2j5tA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgs CIRCULAR PERMUTANT
OF AVIDIN


(Gallus gallus)
PF01382
(Avidin)
4 LEU A   7
LEU A  98
ILE A  75
THR A  53
None
1.05A 5ljbA-2jgsA:
3.0
5ljbA-2jgsA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kdy FACTOR H BINDING
PROTEIN VARIANT
B01_001


(Neisseria
meningitidis)
PF08794
(Lipoprot_C)
4 LEU A  52
LEU A  69
ILE A 137
THR A 113
None
1.03A 5ljbA-2kdyA:
2.0
5ljbA-2kdyA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o62 HYPOTHETICAL PROTEIN

(Nostoc
punctiforme)
PF12204
(DUF3598)
4 LEU A 167
LEU A 239
ILE A 198
GLN A 210
GOL  A 274 (-4.7A)
None
None
GOL  A 277 (-3.2A)
0.99A 5ljbA-2o62A:
8.2
5ljbA-2o62A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY


(Vibrio
parahaemolyticus)
PF03466
(LysR_substrate)
4 LEU A 211
LEU A  31
THR A  23
GLN A 112
None
None
SO4  A 216 ( 3.2A)
SO4  A 216 ( 4.4A)
1.03A 5ljbA-2qsxA:
undetectable
5ljbA-2qsxA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2quq CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
B


(Saccharomyces
cerevisiae)
PF16846
(Cep3)
4 LEU A 162
LEU A 238
ILE A 284
THR A 288
None
0.98A 5ljbA-2quqA:
undetectable
5ljbA-2quqA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qve TYROSINE AMINOMUTASE

(Streptomyces
globisporus)
PF00221
(Lyase_aromatic)
4 LEU A 527
LEU A 222
ILE A 313
GLN A 382
None
0.97A 5ljbA-2qveA:
undetectable
5ljbA-2qveA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r41 UNCHARACTERIZED
PROTEIN


(Enterococcus
faecalis)
PF06124
(DUF960)
4 LEU A  75
LEU A  31
ILE A  41
GLN A  64
None
1.04A 5ljbA-2r41A:
undetectable
5ljbA-2r41A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5v PCZA361.1

(Amycolatopsis
orientalis)
PF00903
(Glyoxalase)
PF14696
(Glyoxalase_5)
4 LEU A 303
ILE A 216
THR A 214
GLN A 240
None
None
HHH  A4114 (-3.1A)
None
0.97A 5ljbA-2r5vA:
undetectable
5ljbA-2r5vA:
15.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rcq RETINOL-BINDING
PROTEIN II, CELLULAR


(Homo sapiens)
PF00061
(Lipocalin)
4 LYS A  40
THR A  53
TRP A 106
GLN A 108
None
0.59A 5ljbA-2rcqA:
23.9
5ljbA-2rcqA:
53.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhz LETHAL(3)MALIGNANT
BRAIN TUMOR-LIKE
PROTEIN


(Homo sapiens)
PF02820
(MBT)
4 LEU A 240
LYS A 243
ILE A 257
THR A 259
None
0.84A 5ljbA-2rhzA:
undetectable
5ljbA-2rhzA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rin PUTATIVE GLYCINE
BETAINE-BINDING ABC
TRANSPORTER PROTEIN


(Sinorhizobium
meliloti)
PF04069
(OpuAC)
4 LEU A 297
LEU A  57
ILE A 267
THR A  52
None
0.95A 5ljbA-2rinA:
undetectable
5ljbA-2rinA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w21 GLUTAMATE 5-KINASE

(Escherichia
coli)
PF00696
(AA_kinase)
4 LEU A 166
ILE A 188
THR A 253
MET A 214
None
0.92A 5ljbA-2w21A:
undetectable
5ljbA-2w21A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj4 GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING] 1


(Homo sapiens)
PF01380
(SIS)
4 LEU A 529
LYS A 635
ILE A 627
THR A 633
None
1.05A 5ljbA-2zj4A:
undetectable
5ljbA-2zj4A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION


(Nostoc
punctiforme)
PF12981
(DUF3865)
4 LEU A 171
LEU A 152
ILE A  49
GLN A  46
None
1.05A 5ljbA-3b5oA:
undetectable
5ljbA-3b5oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5t MALATE DEHYDROGENASE

(Burkholderia
pseudomallei)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 LEU A 117
LEU A  86
ILE A  71
GLN A  48
None
1.01A 5ljbA-3d5tA:
undetectable
5ljbA-3d5tA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fr8 PUTATIVE KETOL-ACID
REDUCTOISOMERASE
(OS05G0573700
PROTEIN)


(Oryza sativa)
PF01450
(IlvC)
PF07991
(IlvN)
4 LEU A 118
LEU A 298
ILE A 107
THR A 303
None
0.99A 5ljbA-3fr8A:
undetectable
5ljbA-3fr8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnr OS03G0212800 PROTEIN

(Oryza sativa)
PF00232
(Glyco_hydro_1)
4 LEU A 201
LEU A 342
ILE A 333
THR A 331
LEU  A 201 ( 0.6A)
LEU  A 342 ( 0.5A)
ILE  A 333 ( 0.4A)
THR  A 331 ( 0.8A)
0.93A 5ljbA-3gnrA:
undetectable
5ljbA-3gnrA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hka URONATE ISOMERASE

(Bacillus
halodurans)
no annotation 4 LEU A  51
LEU A  97
ILE A 334
GLN A 352
None
1.00A 5ljbA-3hkaA:
undetectable
5ljbA-3hkaA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgw ALANINE-GLYOXYLATE
AMINOTRANSFERASE


(Mus musculus)
PF00266
(Aminotran_5)
4 LEU A 115
LEU A  96
ILE A 215
GLN A 220
None
None
None
EDO  A 507 ( 4.7A)
1.01A 5ljbA-3kgwA:
undetectable
5ljbA-3kgwA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmm PUTATIVE CYTOPLASMIC
PROTEIN


(Klebsiella
pneumoniae)
PF07470
(Glyco_hydro_88)
4 LEU A 375
LEU A  27
ILE A  89
THR A  32
None
None
None
FMT  A 387 ( 4.5A)
1.01A 5ljbA-3pmmA:
undetectable
5ljbA-3pmmA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwt PUTATIVE GH105
FAMILY PROTEIN


(Salmonella
enterica)
PF07470
(Glyco_hydro_88)
4 LEU A 168
ILE A 301
THR A 235
TRP A 278
None
1.07A 5ljbA-3qwtA:
undetectable
5ljbA-3qwtA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwt PUTATIVE GH105
FAMILY PROTEIN


(Salmonella
enterica)
PF07470
(Glyco_hydro_88)
4 LEU A 374
LEU A  26
ILE A  88
THR A  31
None
0.98A 5ljbA-3qwtA:
undetectable
5ljbA-3qwtA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmj 2-ISOPROPYLMALATE
SYNTHASE


(Neisseria
meningitidis)
PF00682
(HMGL-like)
4 LEU A 259
LEU A 217
ILE A 170
TRP A 201
None
1.02A 5ljbA-3rmjA:
undetectable
5ljbA-3rmjA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tc3 UV DAMAGE
ENDONUCLEASE


(Sulfolobus
acidocaldarius)
PF03851
(UvdE)
4 LEU A  45
ILE A  63
THR A  62
MET A 132
None
1.05A 5ljbA-3tc3A:
undetectable
5ljbA-3tc3A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttg PUTATIVE
AMINOMETHYLTRANSFERA
SE


(Leptospirillum
rubarum)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
4 LEU A 227
LEU A 211
ILE A 288
THR A 290
None
None
CL  A 336 ( 4.6A)
None
0.90A 5ljbA-3ttgA:
undetectable
5ljbA-3ttgA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3up4 OTEMO

(Pseudomonas
putida)
PF00743
(FMO-like)
4 LEU A 146
ILE A 200
THR A 196
TRP A 170
NAP  A 552 (-4.2A)
None
NAP  A 552 (-3.5A)
None
1.04A 5ljbA-3up4A:
undetectable
5ljbA-3up4A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgj 4-HYDROXYPHENYLPYRUV
IC ACID DIOXYGENASE


(Streptomyces
coelicolor)
PF00903
(Glyoxalase)
PF14696
(Glyoxalase_5)
4 LEU A 323
ILE A 236
THR A 234
GLN A 260
None
RMN  A1369 ( 4.8A)
RMN  A1369 (-3.2A)
RMN  A1369 ( 4.7A)
0.98A 5ljbA-3zgjA:
undetectable
5ljbA-3zgjA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d4l 6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
SPHOSPHATASE 3


(Homo sapiens)
PF00300
(His_Phos_1)
PF01591
(6PF2K)
4 LEU A 369
LEU A 391
ILE A 304
THR A 303
None
0.99A 5ljbA-4d4lA:
undetectable
5ljbA-4d4lA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dd5 ACETYL-COA
ACETYLTRANSFERASE


(Clostridioides
difficile)
PF00108
(Thiolase_N)
PF02803
(Thiolase_C)
4 LEU A 183
ILE A 292
TRP A 173
GLN A 172
None
0.94A 5ljbA-4dd5A:
undetectable
5ljbA-4dd5A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkv ALCOHOL
DEHYDROGENASE,
PROPANOL-PREFERRING


(Escherichia
coli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 LEU A 311
LEU A  56
ILE A 122
MET A   1
None
1.07A 5ljbA-4gkvA:
undetectable
5ljbA-4gkvA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6y FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF00169
(PH)
PF00621
(RhoGEF)
4 LEU A 606
LEU A 599
THR A 551
GLN A 694
None
1.04A 5ljbA-4h6yA:
undetectable
5ljbA-4h6yA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13


(Thermus
thermophilus)
PF00361
(Proton_antipo_M)
4 LEU M 285
LEU M 361
ILE M  78
THR M  81
None
0.98A 5ljbA-4heaM:
undetectable
5ljbA-4heaM:
13.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i9r CELLULAR RETINOIC
ACID-BINDING PROTEIN
2


(Homo sapiens)
PF00061
(Lipocalin)
4 LEU A  19
ILE A  63
TRP A 109
MET A 123
None
RET  A 201 ( 4.7A)
RET  A 201 (-3.7A)
RET  A 201 (-4.6A)
1.00A 5ljbA-4i9rA:
19.5
5ljbA-4i9rA:
43.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ict CYTOCHROME P450 121

(Mycobacterium
tuberculosis)
PF00067
(p450)
4 LEU A 124
LEU A 362
ILE A 388
THR A 243
None
0.95A 5ljbA-4ictA:
undetectable
5ljbA-4ictA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4il5 CYSTEINE SYNTHASE

(Entamoeba
histolytica)
PF00291
(PALP)
4 LEU A 331
ILE A 321
TRP A 263
GLN A 260
None
0.99A 5ljbA-4il5A:
undetectable
5ljbA-4il5A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A


(Mus musculus)
PF13516
(LRR_6)
4 LEU A 386
LEU A 379
THR A 375
MET A 357
None
0.81A 5ljbA-4k17A:
undetectable
5ljbA-4k17A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwz PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE


(Plasmodium
vivax)
PF13649
(Methyltransf_25)
4 LEU A  50
LEU A 153
ILE A  38
THR A  41
None
1.05A 5ljbA-4mwzA:
undetectable
5ljbA-4mwzA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7t PHOSPHOPENTOMUTASE

(Streptococcus
mutans)
PF01676
(Metalloenzyme)
4 LEU A   9
LEU A  83
ILE A 104
TRP A  97
None
1.00A 5ljbA-4n7tA:
undetectable
5ljbA-4n7tA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pbv NT-3 GROWTH FACTOR
RECEPTOR
PROTEIN-TYROSINE
PHOSPHATASE
CRYPALPHA1 ISOFORM


(Gallus gallus;
Gallus gallus)
PF00047
(ig)
PF13855
(LRR_8)
PF16920
(TPKR_C2)
PF07679
(I-set)
PF13927
(Ig_3)
4 LEU A 139
LEU A  94
TRP A 144
GLN C  75
None
0.73A 5ljbA-4pbvA:
undetectable
5ljbA-4pbvA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE


(Bradyrhizobium
diazoefficiens)
PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg)
4 LEU A 458
LEU A  67
ILE A 922
THR A 139
None
1.06A 5ljbA-4q73A:
undetectable
5ljbA-4q73A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r85 CYTOSINE DEAMINASE

(Klebsiella
pneumoniae)
PF07969
(Amidohydro_3)
4 LEU A 144
LEU A 100
ILE A  90
THR A  95
None
0.98A 5ljbA-4r85A:
undetectable
5ljbA-4r85A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgy ESTERASE

(uncultured
bacterium FLS12)
PF00756
(Esterase)
5 LEU A 193
LEU A 134
ILE A 176
THR A  86
GLN A 173
None
1.45A 5ljbA-4rgyA:
undetectable
5ljbA-4rgyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryk LMO0325 PROTEIN

(Listeria
monocytogenes)
PF01381
(HTH_3)
4 LEU A 181
LEU A 200
ILE A 250
GLN A 247
None
1.04A 5ljbA-4rykA:
undetectable
5ljbA-4rykA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryk LMO0325 PROTEIN

(Listeria
monocytogenes)
PF01381
(HTH_3)
4 LEU A 181
LEU A 200
THR A 205
GLN A 247
None
0.99A 5ljbA-4rykA:
undetectable
5ljbA-4rykA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s0h T-BOX TRANSCRIPTION
FACTOR TBX5


(Homo sapiens)
PF00907
(T-box)
4 LEU A  58
LEU A  63
ILE A 212
THR A  72
None
1.05A 5ljbA-4s0hA:
undetectable
5ljbA-4s0hA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4trk C. ELEGANS HIM-3

(Caenorhabditis
elegans)
PF02301
(HORMA)
4 LEU A 182
LEU A  51
ILE A 225
MET A 179
None
0.89A 5ljbA-4trkA:
undetectable
5ljbA-4trkA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5


(Drosophila
melanogaster;
Drosophila
melanogaster)
PF13191
(AAA_16)
PF14629
(ORC4_C)
PF13191
(AAA_16)
PF14630
(ORC5_C)
4 LEU E 102
LEU E 148
ILE D  85
GLN D 245
None
1.04A 5ljbA-4xgcE:
undetectable
5ljbA-4xgcE:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwh ALPHA-N-ACETYLGLUCOS
AMINIDASE


(Homo sapiens)
PF05089
(NAGLU)
PF12971
(NAGLU_N)
PF12972
(NAGLU_C)
4 LEU A 622
LEU A 666
ILE A 448
TRP A 145
None
1.04A 5ljbA-4xwhA:
undetectable
5ljbA-4xwhA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwj CHIMERA PROTEIN OF
HUMAN RHODOPSIN,
MOUSE S-ARRESTIN,
AND T4 ENDOLYSIN


(Homo sapiens;
Mus musculus;
Escherichia
virus T4)
PF00001
(7tm_1)
PF00339
(Arrestin_N)
PF00959
(Phage_lysozyme)
PF02752
(Arrestin_C)
PF10413
(Rhodopsin_N)
4 LEU A  47
ILE A 286
THR A 289
GLN A  36
None
1.06A 5ljbA-4zwjA:
undetectable
5ljbA-4zwjA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzh NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-1


(Homo sapiens)
PF02146
(SIR2)
4 LEU A 228
LEU A 202
ILE A 194
THR A 196
None
0.96A 5ljbA-4zzhA:
undetectable
5ljbA-4zzhA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ajz 6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
SPHOSPHATASE 3


(Homo sapiens)
PF00300
(His_Phos_1)
PF01591
(6PF2K)
4 LEU A 369
LEU A 391
ILE A 304
THR A 303
None
0.98A 5ljbA-5ajzA:
undetectable
5ljbA-5ajzA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aor DOSAGE COMPENSATION
REGULATOR


(Drosophila
melanogaster)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind)
4 LEU A 665
ILE A 719
THR A 717
GLN A 699
None
U  C   7 ( 3.9A)
U  C   7 ( 2.9A)
None
0.89A 5ljbA-5aorA:
undetectable
5ljbA-5aorA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp7 SAM-DEPENDENT
METHYLTRANSFERASE


(Geobacter
sulfurreducens)
PF13847
(Methyltransf_31)
4 LEU A 171
LEU A 178
ILE A 116
THR A 123
None
None
SAH  A 301 ( 4.6A)
None
1.00A 5ljbA-5bp7A:
undetectable
5ljbA-5bp7A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq2 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Pseudomonas
aeruginosa)
PF00275
(EPSP_synthase)
4 LEU A   4
LEU A 384
ILE A 236
THR A 240
None
0.95A 5ljbA-5bq2A:
undetectable
5ljbA-5bq2A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6g AGR133CP
SISTER CHROMATID
COHESION PROTEIN 2


(Eremothecium
gossypii;
Eremothecium
gossypii)
PF10345
(Cohesin_load)
no annotation
4 LEU B  19
LEU A 584
GLN A 609
MET A 612
None
0.95A 5ljbA-5c6gB:
undetectable
5ljbA-5c6gB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cgz 4-OXALMESACONATE
HYDRATASE


(Pseudomonas
putida)
PF02585
(PIG-L)
4 LEU A 115
LEU A 177
ILE A 190
TRP A  20
None
1.06A 5ljbA-5cgzA:
undetectable
5ljbA-5cgzA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hee PUTATIVE
UNCHARACTERIZED
PROTEIN, TK2203
PROTEIN


(Thermococcus
kodakarensis)
PF02900
(LigB)
4 LEU A  64
LEU A  44
ILE A  52
THR A 137
None
0.96A 5ljbA-5heeA:
undetectable
5ljbA-5heeA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxa ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)


(Paraburkholderia
xenovorans)
PF00982
(Glyco_transf_20)
4 LEU A 302
LEU A 279
THR A 367
GLN A 417
None
0.81A 5ljbA-5hxaA:
undetectable
5ljbA-5hxaA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hyh UNCHARACTERIZED
PROTEIN


(Streptomyces
venezuelae)
PF11583
(AurF)
4 LEU A 195
ILE A 206
THR A 202
MET A 323
None
0.98A 5ljbA-5hyhA:
undetectable
5ljbA-5hyhA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F


(Escherichia
coli)
PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C)
4 LEU A1088
LEU A1135
ILE A1057
GLN A1126
None
0.94A 5ljbA-5ja1A:
undetectable
5ljbA-5ja1A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1s OXIDOREDUCTASE,
ZINC-BINDING
DEHYDROGENASE FAMILY


(Myxococcus
xanthus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 LEU A 117
ILE A  69
GLN A  -2
MET A   1
None
1.01A 5ljbA-5k1sA:
undetectable
5ljbA-5k1sA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kc9 GLUTAMATE RECEPTOR
IONOTROPIC, DELTA-1


(Mus musculus)
PF01094
(ANF_receptor)
4 LEU A 270
LEU A 231
ILE A 318
GLN A 283
BU1  A 520 (-4.1A)
None
None
None
1.04A 5ljbA-5kc9A:
undetectable
5ljbA-5kc9A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kod INDOLE-3-ACETIC
ACID-AMIDO
SYNTHETASE GH3.5


(Arabidopsis
thaliana)
PF03321
(GH3)
4 LEU A 250
LEU A 259
ILE A 202
THR A 201
None
1.03A 5ljbA-5kodA:
undetectable
5ljbA-5kodA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldr BETA-D-GALACTOSIDASE

(Paracoccus sp.
32d)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
4 LEU B 254
LEU B 166
ILE B 160
THR B 162
None
None
None
CL  B 806 ( 4.7A)
1.05A 5ljbA-5ldrB:
undetectable
5ljbA-5ldrB:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn7 URACIL-DNA
GLYCOSYLASE


(Human
gammaherpesvirus
8)
no annotation 4 LEU A  41
ILE A  52
GLN A  65
MET A  69
None
0.68A 5ljbA-5nn7A:
undetectable
5ljbA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn7 URACIL-DNA
GLYCOSYLASE


(Human
gammaherpesvirus
8)
no annotation 4 LEU A 217
LEU A 214
ILE A 115
TRP A 187
None
0.92A 5ljbA-5nn7A:
undetectable
5ljbA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opt RIBOSOMAL PROTEIN
S19, PUTATIVE


(Trypanosoma
cruzi)
no annotation 4 LEU o 127
LEU o 117
ILE o 108
GLN o  65
None
0.92A 5ljbA-5opto:
undetectable
5ljbA-5opto:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1


(Glycine max)
no annotation 4 LEU A 546
LEU A 496
ILE A 704
THR A 709
None
1.04A 5ljbA-5tr0A:
undetectable
5ljbA-5tr0A:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens)
no annotation 4 LEU A 814
LEU A 721
ILE A 689
THR A 690
None
1.04A 5ljbA-5vanA:
undetectable
5ljbA-5vanA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xap PROTEIN TRANSLOCASE
SUBUNIT SECD


(Deinococcus
radiodurans)
PF02355
(SecD_SecF)
PF07549
(Sec_GG)
4 LEU A  76
ILE A 430
THR A 427
MET A  70
None
1.00A 5ljbA-5xapA:
undetectable
5ljbA-5xapA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xh9 EXTRACELLULAR
INVERTASE


(Aspergillus
kawachii)
PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C)
4 LEU A 393
LEU A  82
ILE A 293
THR A 272
None
1.06A 5ljbA-5xh9A:
undetectable
5ljbA-5xh9A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y58 ATP-DEPENDENT DNA
HELICASE II SUBUNIT
1
ATP-DEPENDENT DNA
HELICASE II SUBUNIT
2


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
no annotation
no annotation
4 LEU A 432
LEU A 405
ILE B 585
THR A 400
None
1.06A 5ljbA-5y58A:
undetectable
5ljbA-5y58A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE


(Moorella
thermoacetica)
no annotation 4 LEU A 325
LEU A 297
ILE A 407
THR A 284
None
0.97A 5ljbA-6cipA:
undetectable
5ljbA-6cipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Pseudomonas
putida)
no annotation 4 LEU A   4
LEU A 384
ILE A 236
THR A 240
None
1.03A 5ljbA-6cn1A:
undetectable
5ljbA-6cn1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 HUNTINGTIN

(Homo sapiens)
no annotation 4 LEU A1293
LEU A1142
ILE A1087
GLN A1083
None
0.98A 5ljbA-6ez8A:
undetectable
5ljbA-6ez8A:
undetectable