SIMILAR PATTERNS OF AMINO ACIDS FOR 5LG3_G_Z80G401
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aql | BILE-SALT ACTIVATEDLIPASE (Bos taurus) |
PF00135(COesterase) | 5 | ILE A 102ILE A 188VAL A 139ASP A 184ILE A 178 | None | 1.23A | 5lg3G-1aqlA:0.0 | 5lg3G-1aqlA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aux | SYNAPSIN IA (Bos taurus) |
PF02078(Synapsin)PF02750(Synapsin_C) | 5 | ILE A 308VAL A 267GLU A 373ASP A 313ILE A 385 | AGS A 800 (-3.9A)AGS A 800 ( 4.8A) CA A 801 ( 2.3A)AGS A 800 ( 4.4A)AGS A 800 (-4.3A) | 1.27A | 5lg3G-1auxA:undetectable | 5lg3G-1auxA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cr5 | SEC18P (RESIDUES 22- 210) (Saccharomycescerevisiae) |
PF02359(CDC48_N)PF02933(CDC48_2) | 5 | ILE A 119ILE A 121PHE A 167GLU A 138ASP A 135 | None | 1.27A | 5lg3G-1cr5A:0.0 | 5lg3G-1cr5A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hzo | BETA-LACTAMASE (Proteusvulgaris) |
PF13354(Beta-lactamase2) | 5 | ILE A 29ILE A 57GLU A 52ASP A 53ILE A 290 | None | 1.21A | 5lg3G-1hzoA:0.1 | 5lg3G-1hzoA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1id0 | PHOQ HISTIDINEKINASE (Escherichiacoli) |
PF02518(HATPase_c) | 5 | ILE A 411ILE A 400VAL A 474ASN A 389ASP A 415 | NoneNoneNoneANP A 487 (-3.0A)ANP A 487 (-3.7A) | 1.26A | 5lg3G-1id0A:0.0 | 5lg3G-1id0A:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1idj | PECTIN LYASE A (Aspergillusniger) |
PF00544(Pec_lyase_C) | 5 | ILE A 140ILE A 121VAL A 169THR A 171ILE A 156 | None | 1.21A | 5lg3G-1idjA:undetectable | 5lg3G-1idjA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcl | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 5 | ILE A 215PHE A 136VAL A 252ASP A 220ILE A 223 | None | 1.26A | 5lg3G-1kclA:0.6 | 5lg3G-1kclA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pk8 | RAT SYNAPSIN I (Rattusnorvegicus) |
PF02078(Synapsin)PF02750(Synapsin_C) | 5 | ILE A 308VAL A 267GLU A 373ASP A 313ILE A 385 | ATP A 800 (-4.1A)ATP A 800 (-4.3A) CA A 817 ( 2.2A)ATP A 800 (-3.6A)ATP A 800 ( 4.5A) | 1.14A | 5lg3G-1pk8A:0.0 | 5lg3G-1pk8A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qcx | PECTIN LYASE B (Aspergillusniger) |
PF00544(Pec_lyase_C) | 5 | ILE A 140ILE A 121VAL A 169THR A 171ILE A 156 | None | 1.25A | 5lg3G-1qcxA:undetectable | 5lg3G-1qcxA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sky | F1-ATPASE (Bacillus sp.PS3) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N) | 5 | ILE B 335ILE B 326PHE B 343VAL B 334GLU B 320 | None | 1.18A | 5lg3G-1skyB:undetectable | 5lg3G-1skyB:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuf | DIAMINOPIMELATEDECARBOXYLASE (Methanocaldococcusjannaschii) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | ILE A 225PHE A 235VAL A 242ASN A 260GLU A 304 | NoneNoneNoneNoneLLP A 83 ( 3.6A) | 1.28A | 5lg3G-1tufA:undetectable | 5lg3G-1tufA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vj7 | BIFUNCTIONALRELA/SPOT (Streptococcusdysgalactiae) |
PF04607(RelA_SpoT)PF13328(HD_4) | 5 | ILE A 322ILE A 268VAL A 315THR A 313ILE A 285 | None | 1.04A | 5lg3G-1vj7A:undetectable | 5lg3G-1vj7A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wle | SERYL-TRNASYNTHETASE (Bos taurus) |
PF00587(tRNA-synt_2b) | 5 | ILE A 473ILE A 197VAL A 458GLU A 190ILE A 191 | None | 1.16A | 5lg3G-1wleA:undetectable | 5lg3G-1wleA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zc1 | UBIQUITIN FUSIONDEGRADATION PROTEIN1 (Saccharomycescerevisiae) |
PF03152(UFD1) | 5 | ILE A 173ILE A 160PHE A 151VAL A 125THR A 194 | None | 1.14A | 5lg3G-1zc1A:undetectable | 5lg3G-1zc1A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zd0 | HYPOTHETICAL PROTEINPF0523 (Pyrococcusfuriosus) |
PF08617(CGI-121) | 5 | ILE A 103ILE A 123VAL A 43GLU A 98ILE A 30 | NoneNoneNoneUNX A 406 ( 4.4A)None | 1.29A | 5lg3G-1zd0A:undetectable | 5lg3G-1zd0A:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zjc | AMINOPEPTIDASE AMPS (Staphylococcusaureus) |
PF02073(Peptidase_M29) | 5 | ILE A 351ILE A 308PHE A 295VAL A 382ILE A 280 | None | 1.22A | 5lg3G-1zjcA:undetectable | 5lg3G-1zjcA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cl2 | PUTATIVELAMINARINASE (Phanerochaetechrysosporium) |
no annotation | 5 | ILE A 291ILE A 249VAL A 89ASN A 128ILE A 119 | None | 1.08A | 5lg3G-2cl2A:undetectable | 5lg3G-2cl2A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cl2 | PUTATIVELAMINARINASE (Phanerochaetechrysosporium) |
no annotation | 5 | ILE A 291ILE A 249VAL A 89TRP A 103ILE A 119 | None | 1.14A | 5lg3G-2cl2A:undetectable | 5lg3G-2cl2A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dk5 | DNA-DIRECTED RNAPOLYMERASE III 39KDA POLYPEPTIDE (Homo sapiens) |
PF05158(RNA_pol_Rpc34) | 5 | ILE A 28ILE A 37VAL A 25ASN A 54TRP A 38 | None | 1.14A | 5lg3G-2dk5A:undetectable | 5lg3G-2dk5A:14.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dk5 | DNA-DIRECTED RNAPOLYMERASE III 39KDA POLYPEPTIDE (Homo sapiens) |
PF05158(RNA_pol_Rpc34) | 5 | ILE A 28ILE A 37VAL A 25TRP A 38ILE A 53 | None | 1.25A | 5lg3G-2dk5A:undetectable | 5lg3G-2dk5A:14.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hck | HEMATOPOETIC CELLKINASE HCK (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1)PF07714(Pkinase_Tyr) | 5 | ILE A 392ILE A 370PHE A 448ASP A 365ILE A 455 | None | 1.08A | 5lg3G-2hckA:undetectable | 5lg3G-2hckA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk5 | TYROSINE-PROTEINKINASE HCK (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | ILE A 370ILE A 348PHE A 426ASP A 343ILE A 433 | None | 1.18A | 5lg3G-2hk5A:1.3 | 5lg3G-2hk5A:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hl7 | CYTOCHROME C-TYPEBIOGENESIS PROTEINCCMH (Pseudomonasaeruginosa) |
PF03918(CcmH) | 5 | ILE A 61ILE A 48PHE A 16ASP A 43ILE A 33 | None | 1.23A | 5lg3G-2hl7A:undetectable | 5lg3G-2hl7A:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hxd | DCTP DEAMINASE,DUMP-FORMING (Methanocaldococcusjannaschii) |
PF00692(dUTPase) | 5 | ILE A 42ILE A 59VAL A 96ASP A 38ILE A 65 | None | 0.98A | 5lg3G-2hxdA:undetectable | 5lg3G-2hxdA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k49 | UPF0339 PROTEINSO_3888 (Shewanellaoneidensis) |
PF07411(DUF1508) | 5 | ILE A 106ILE A 43PHE A 17THR A 103ASN A 100 | None | 1.23A | 5lg3G-2k49A:undetectable | 5lg3G-2k49A:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lv4 | PUTATIVE OUTERMEMBRANE OR EXPORTEDPROTEIN (Salmonellaenterica) |
PF16583(ZirS_C) | 5 | ILE A 258ILE A 272VAL A 219ASN A 223GLU A 254 | None | 0.84A | 5lg3G-2lv4A:undetectable | 5lg3G-2lv4A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2og8 | PROTO-ONCOGENETYROSINE-PROTEINKINASE LCK (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | ILE A 370ILE A 348PHE A 426ASP A 343ILE A 433 | None | 1.06A | 5lg3G-2og8A:undetectable | 5lg3G-2og8A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ohg | GLUTAMATE RACEMASE (Streptococcuspyogenes) |
PF01177(Asp_Glu_race) | 5 | ILE A 137ILE A 104VAL A 112THR A 178ILE A 204 | None | 1.27A | 5lg3G-2ohgA:undetectable | 5lg3G-2ohgA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qkx | BIFUNCTIONAL PROTEINGLMU (Mycobacteriumtuberculosis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | ILE A 274ILE A 286VAL A 278THR A 296ILE A 298 | None | 1.24A | 5lg3G-2qkxA:undetectable | 5lg3G-2qkxA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rkc | HEMAGGLUTININ (Measlesmorbillivirus) |
PF00423(HN) | 5 | ILE A 306VAL A 367THR A 369ASP A 347ILE A 427 | None | 1.16A | 5lg3G-2rkcA:undetectable | 5lg3G-2rkcA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxx | DIAMINOPIMELATEDECARBOXYLASE (Thermotogamaritima) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | ILE A 180PHE A 190VAL A 197ASN A 210GLU A 246 | NoneNoneNoneNonePLP A 401 (-3.6A) | 1.29A | 5lg3G-2yxxA:undetectable | 5lg3G-2yxxA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z61 | PROBABLE ASPARTATEAMINOTRANSFERASE 2 (Methanocaldococcusjannaschii) |
PF00155(Aminotran_1_2) | 5 | ILE A 217ILE A 187VAL A 234ASN A 237ILE A 240 | None | 1.02A | 5lg3G-2z61A:undetectable | 5lg3G-2z61A:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zj8 | PUTATIVE SKI2-TYPEHELICASE (Pyrococcusfuriosus) |
PF00270(DEAD)PF00271(Helicase_C)PF14520(HHH_5) | 5 | ILE A 673PHE A 667VAL A 654THR A 691ILE A 687 | None | 1.12A | 5lg3G-2zj8A:undetectable | 5lg3G-2zj8A:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zu8 | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Pyrococcushorikoshii) |
PF09488(Osmo_MPGsynth) | 5 | ILE A 82ILE A 112PHE A 104VAL A 57ILE A 74 | None | 1.07A | 5lg3G-2zu8A:undetectable | 5lg3G-2zu8A:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zuf | ARGINYL-TRNASYNTHETASE (Pyrococcushorikoshii) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 5 | ILE A 76ILE A 90PHE A 95VAL A 9GLU A 32 | None | 1.26A | 5lg3G-2zufA:undetectable | 5lg3G-2zufA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aja | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycolicibacteriumsmegmatis) |
PF01083(Cutinase) | 5 | ILE A 172ILE A 189VAL A 204THR A 261ASN A 259 | None | 1.28A | 5lg3G-3ajaA:undetectable | 5lg3G-3ajaA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3auf | GLYCINAMIDERIBONUCLEOTIDETRANSFORMYLASE 1 (Symbiobacteriumtoebii) |
PF00551(Formyl_trans_N) | 5 | ILE A 4ILE A 182VAL A 6ASN A 14GLU A 174 | None | 1.25A | 5lg3G-3aufA:undetectable | 5lg3G-3aufA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b6y | GAMMA-INTERFERON-INDUCIBLE PROTEINIFI-16 (Homo sapiens) |
PF02760(HIN) | 5 | PHE A 41VAL A 74THR A 78ASP A 6ILE A 62 | None | 1.19A | 5lg3G-3b6yA:undetectable | 5lg3G-3b6yA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bmw | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Thermoanaerobacteriumthermosulfurigenes) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | ILE A 216PHE A 137VAL A 253ASP A 221ILE A 224 | None | 1.14A | 5lg3G-3bmwA:undetectable | 5lg3G-3bmwA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bmw | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Thermoanaerobacteriumthermosulfurigenes) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | ILE A 247ILE A 216PHE A 137VAL A 253ILE A 224 | None | 1.18A | 5lg3G-3bmwA:undetectable | 5lg3G-3bmwA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cj8 | 2,3,4,5-TETRAHYDROPYRIDINE-2,6-DICARBOXYLATEN-ACETYLTRANSFERASE (Enterococcusfaecalis) |
PF00132(Hexapep)PF08503(DapH_N)PF14602(Hexapep_2) | 5 | ILE A 165ILE A 171VAL A 139THR A 125ILE A 127 | None | 0.96A | 5lg3G-3cj8A:undetectable | 5lg3G-3cj8A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cta | RIBOFLAVIN KINASE (Thermoplasmaacidophilum) |
PF01982(CTP-dep_RFKase)PF13545(HTH_Crp_2) | 5 | ILE A 196ILE A 134VAL A 182ASP A 192ILE A 95 | None | 1.07A | 5lg3G-3ctaA:undetectable | 5lg3G-3ctaA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3deg | GTP-BINDING PROTEINLEPA (Escherichiacoli) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF06421(LepA_C) | 5 | ILE C 532ILE C 537VAL C 481THR C 499ASN C 503 | None A A 67 ( 4.8A)NoneNoneNone | 1.21A | 5lg3G-3degC:undetectable | 5lg3G-3degC:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ege | PUTATIVEMETHYLTRANSFERASEFROM ANTIBIOTICBIOSYNTHESIS PATHWAY (Trichormusvariabilis) |
PF08241(Methyltransf_11) | 5 | ILE A 98ILE A 37VAL A 126THR A 124ASN A 30 | None | 1.21A | 5lg3G-3egeA:undetectable | 5lg3G-3egeA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eh0 | UDP-3-O-[3-HYDROXYMYRISTOYL] GLUCOSAMINEN-ACYLTRANSFERASE (Escherichiacoli) |
PF00132(Hexapep)PF04613(LpxD)PF14602(Hexapep_2) | 5 | ILE A 231ILE A 225VAL A 249THR A 247ILE A 261 | None | 1.14A | 5lg3G-3eh0A:undetectable | 5lg3G-3eh0A:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i5q | NUCLEOPORIN NUP170 (Saccharomycescerevisiae) |
no annotation | 5 | ILE B1271ILE B1275PHE B1311VAL B1268ASP B1298 | None | 1.10A | 5lg3G-3i5qB:undetectable | 5lg3G-3i5qB:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kbh | ANGIOTENSIN-CONVERTING ENZYME 2 (Homo sapiens) |
PF01401(Peptidase_M2) | 5 | ILE A 223VAL A 226ASP A 206TRP A 203ILE A 513 | None | 1.20A | 5lg3G-3kbhA:1.6 | 5lg3G-3kbhA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3msg | INTRA-CELLULARXYLANASE IXT6 (Geobacillusstearothermophilus) |
PF00331(Glyco_hydro_10) | 5 | ILE A 223ILE A 274PHE A 275ASP A 243ILE A 239 | None | 1.23A | 5lg3G-3msgA:undetectable | 5lg3G-3msgA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndn | O-SUCCINYLHOMOSERINESULFHYDRYLASE (Mycobacteriumtuberculosis) |
PF01053(Cys_Met_Meta_PP) | 5 | ILE A 387ILE A 401PHE A 286VAL A 389ASP A 396 | None | 1.25A | 5lg3G-3ndnA:undetectable | 5lg3G-3ndnA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ob8 | BETA-GALACTOSIDASE (Kluyveromyceslactis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N) | 5 | ILE A 648ILE A 657VAL A 700THR A 697ILE A 680 | None | 1.23A | 5lg3G-3ob8A:undetectable | 5lg3G-3ob8A:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3plr | UDP-GLUCOSE6-DEHYDROGENASE (Klebsiellapneumoniae) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | ILE A 101ILE A 127VAL A 97THR A 94ILE A 119 | None | 1.21A | 5lg3G-3plrA:undetectable | 5lg3G-3plrA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qki | GLUCOSE-6-PHOSPHATEISOMERASE (Plasmodiumfalciparum) |
PF00342(PGI) | 5 | ILE A 303ILE A 128PHE A 285ASP A 133ILE A 308 | None | 1.21A | 5lg3G-3qkiA:undetectable | 5lg3G-3qkiA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0s | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Campylobacterjejuni) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | ILE A 95ILE A 108VAL A 64THR A 50ILE A 52 | None | 0.95A | 5lg3G-3r0sA:undetectable | 5lg3G-3r0sA:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sgz | HYDROXYACID OXIDASE2 (Rattusnorvegicus) |
PF01070(FMN_dh) | 5 | ILE A 72ILE A 298THR A 61GLU A 274ILE A 63 | None | 1.27A | 5lg3G-3sgzA:undetectable | 5lg3G-3sgzA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7y | YOP PROTEINSTRANSLOCATIONPROTEIN U (Chlamydiatrachomatis) |
PF01312(Bac_export_2) | 5 | ILE A 270ILE A 282VAL A 333THR A 329GLU A 318 | None | 1.19A | 5lg3G-3t7yA:undetectable | 5lg3G-3t7yA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uiz | CHIMERA PROTEIN OFSEFD AND SEFA (Salmonellaenterica) |
PF05775(AfaD) | 5 | ILE A 138ILE A 103PHE A 97VAL A 136ILE A 67 | None | 1.26A | 5lg3G-3uizA:undetectable | 5lg3G-3uizA:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uvj | GUANYLATE CYCLASESOLUBLE SUBUNITALPHA-3 (Homo sapiens) |
PF00211(Guanylate_cyc) | 5 | ILE A 571ILE A 487PHE A 490VAL A 563ASN A 507 | None | 1.11A | 5lg3G-3uvjA:1.7 | 5lg3G-3uvjA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4b | STARVATION SENSINGPROTEIN RSPA (Cellvibriojaponicus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 274PHE A 301THR A 284ASP A 269ILE A 298 | None | 1.29A | 5lg3G-3v4bA:undetectable | 5lg3G-3v4bA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrb | FLAVOPROTEIN SUBUNITOF COMPLEX IIIRON-SULFUR SUBUNITOF SUCCINATEDEHYDROGENASE (Ascaris suum) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF13085(Fer2_3)PF13534(Fer4_17) | 5 | ILE B 132ILE A 538VAL B 136THR B 84ASP A 534 | None | 1.02A | 5lg3G-3vrbB:undetectable | 5lg3G-3vrbB:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9y | DISKS LARGE HOMOLOG1 (Homo sapiens) |
PF00625(Guanylate_kin) | 5 | ILE A 909ILE A 848VAL A 906ASN A 750ILE A 741 | None | 1.25A | 5lg3G-3w9yA:undetectable | 5lg3G-3w9yA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqu | CELL DIVISIONPROTEIN FTSA (Staphylococcusaureus) |
PF02491(SHS2_FTSA)PF14450(FtsA) | 5 | ILE A 56VAL A 16THR A 38ASP A 48ILE A 41 | None | 1.27A | 5lg3G-3wquA:undetectable | 5lg3G-3wquA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wt0 | CELL DIVISIONPROTEIN FTSA (Staphylococcusaureus) |
PF02491(SHS2_FTSA)PF14450(FtsA) | 5 | ILE A 56VAL A 16THR A 38ASP A 48ILE A 41 | None | 1.24A | 5lg3G-3wt0A:undetectable | 5lg3G-3wt0A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | ILE V1339ILE V1407GLU V1288ASP V1332ILE V1284 | None | 1.23A | 5lg3G-4bxsV:undetectable | 5lg3G-4bxsV:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0h | MRNA CLEAVAGE ANDPOLYADENYLATIONFACTOR CLP1 (Saccharomycescerevisiae) |
PF06807(Clp1)PF16573(CLP1_N)PF16575(CLP1_P) | 5 | ILE A 411VAL A 414GLU A 351ASP A 352ILE A 376 | None | 1.13A | 5lg3G-4c0hA:undetectable | 5lg3G-4c0hA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4f | MANNONATEDEHYDRATASE (Pectobacteriumcarotovorum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 276PHE A 303THR A 286ASP A 271ILE A 300 | None | 1.18A | 5lg3G-4e4fA:undetectable | 5lg3G-4e4fA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g9k | ROTENONE-INSENSITIVENADH-UBIQUINONEOXIDOREDUCTASE (Saccharomycescerevisiae) |
PF07992(Pyr_redox_2) | 5 | ILE A 336PHE A 208VAL A 233ASP A 249ILE A 268 | ILE A 336 ( 0.7A)PHE A 208 ( 1.3A)VAL A 233 ( 0.6A)ASP A 249 ( 0.6A)ILE A 268 ( 0.7A) | 1.24A | 5lg3G-4g9kA:undetectable | 5lg3G-4g9kA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gaa | MGC78867 PROTEIN (Xenopus laevis) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 5 | ILE A 257ILE A 217VAL A 275THR A 273ILE A 290 | None | 1.06A | 5lg3G-4gaaA:2.4 | 5lg3G-4gaaA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h41 | PUTATIVEALPHA-L-FUCOSIDASE (Bacteroidesthetaiotaomicron) |
PF14488(DUF4434)PF17134(DUF5109) | 5 | ILE A 273ILE A 225PHE A 268GLU A 249TRP A 252 | None | 1.21A | 5lg3G-4h41A:undetectable | 5lg3G-4h41A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il2 | STARVATION SENSINGPROTEIN RSPA (Escherichiacoli) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 287PHE A 314THR A 297ASP A 282ILE A 311 | None | 1.21A | 5lg3G-4il2A:undetectable | 5lg3G-4il2A:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lua | N-ACETYLTRANSFERASE (Staphylococcusaureus) |
PF13420(Acetyltransf_4) | 5 | ILE A 44ILE A 41PHE A 12VAL A 54THR A 66 | None | 1.27A | 5lg3G-4luaA:undetectable | 5lg3G-4luaA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m75 | U6 SNRNA-ASSOCIATEDSM-LIKE PROTEIN LSM6 (Saccharomycescerevisiae) |
PF01423(LSM) | 5 | ILE D 41ILE D 19PHE D 15VAL D 47ASN D 25 | None | 1.19A | 5lg3G-4m75D:undetectable | 5lg3G-4m75D:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn8 | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | ILE A 164ILE A 173VAL A 160ASN A 178ASP A 176 | None | 1.25A | 5lg3G-4mn8A:undetectable | 5lg3G-4mn8A:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mzu | WXCM-LIKE PROTEIN (Shewanelladenitrificans) |
PF00132(Hexapep)PF05523(FdtA) | 5 | ILE A 67ILE A 61VAL A 99THR A 97ILE A 111 | None | 1.23A | 5lg3G-4mzuA:undetectable | 5lg3G-4mzuA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ni2 | GUANYLATE CYCLASESOLUBLE SUBUNITALPHA-3 (Homo sapiens) |
PF00211(Guanylate_cyc) | 5 | ILE A 571ILE A 487PHE A 490VAL A 563ASN A 507 | NoneEDO A 702 (-3.8A)EDO A 702 ( 3.0A)NoneNone | 1.19A | 5lg3G-4ni2A:1.7 | 5lg3G-4ni2A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oca | UDP-4-AMINO-4-DEOXY-L-ARABINOSE--OXOGLUTARATEAMINOTRANSFERASE (Salmonellaenterica) |
PF01041(DegT_DnrJ_EryC1) | 5 | ILE A 181ILE A 158VAL A 198THR A 200ASN A 202 | None | 1.25A | 5lg3G-4ocaA:undetectable | 5lg3G-4ocaA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oer | NIKA PROTEIN (Brucella suis) |
PF00496(SBP_bac_5) | 5 | ILE A 140ILE A 154THR A 88ASN A 92ASP A 152 | None | 1.28A | 5lg3G-4oerA:undetectable | 5lg3G-4oerA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oya | ADENYLATE CYCLASETYPE 10 (Homo sapiens) |
PF00211(Guanylate_cyc) | 5 | ILE A 79ILE A 48VAL A 396THR A 405ILE A 407 | None | 0.99A | 5lg3G-4oyaA:undetectable | 5lg3G-4oyaA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 5 | ILE A 117VAL A 122THR A 125ASN A 129ILE A 160 | None | 1.10A | 5lg3G-4s3jA:undetectable | 5lg3G-4s3jA:22.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4twf | CYS-LOOPLIGAND-GATED IONCHANNEL (Dickeyachrysanthemi) |
PF02931(Neur_chan_LBD) | 6 | ILE A 20ILE A 23PHE A 126ASP A 158TRP A 160ILE A 162 | None | 0.67A | 5lg3G-4twfA:32.6 | 5lg3G-4twfA:99.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgc | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 1 (Drosophilamelanogaster) |
PF00004(AAA)PF09079(Cdc6_C) | 5 | ILE A 612VAL A 608THR A 605GLU A 685ILE A 716 | None | 1.18A | 5lg3G-4xgcA:undetectable | 5lg3G-4xgcA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y68 | PUTATIVENISIN-RESISTANCEPROTEIN (Streptococcusagalactiae) |
no annotation | 5 | ILE C 228PHE C 245THR C 234ASN C 168ASP C 164 | None | 1.20A | 5lg3G-4y68C:undetectable | 5lg3G-4y68C:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y68 | PUTATIVENISIN-RESISTANCEPROTEIN (Streptococcusagalactiae) |
no annotation | 5 | ILE C 296PHE C 245THR C 234ASN C 168ASP C 164 | None | 1.25A | 5lg3G-4y68C:undetectable | 5lg3G-4y68C:20.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 20ILE A 23PHE A 126ASP A 158TRP A 160 | None | 0.50A | 5lg3G-4yeuA:29.4 | 5lg3G-4yeuA:71.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 20ILE A 23PHE A 126TRP A 160ILE A 162 | None | 0.70A | 5lg3G-4yeuA:29.4 | 5lg3G-4yeuA:71.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 20ILE A 23PHE A 126VAL A 147TRP A 160 | None | 0.56A | 5lg3G-4yeuA:29.4 | 5lg3G-4yeuA:71.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 23PHE A 126THR A 149ASP A 158TRP A 160 | None | 1.28A | 5lg3G-4yeuA:29.4 | 5lg3G-4yeuA:71.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 23PHE A 126THR A 149TRP A 160ILE A 162 | None | 0.88A | 5lg3G-4yeuA:29.4 | 5lg3G-4yeuA:71.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | ILE A 23PHE A 126VAL A 147THR A 149TRP A 160 | None | 1.22A | 5lg3G-4yeuA:29.4 | 5lg3G-4yeuA:71.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5adv | ENTEROCHELIN UPTAKEPERIPLASMIC BINDINGPROTEIN (Campylobacterjejuni) |
PF01497(Peripla_BP_2) | 5 | ILE A 244ILE A 236VAL A 246THR A 192ILE A 262 | None | 1.24A | 5lg3G-5advA:undetectable | 5lg3G-5advA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dot | CARBAMOYL-PHOSPHATESYNTHASE [AMMONIA],MITOCHONDRIAL (Homo sapiens) |
PF00117(GATase)PF00988(CPSase_sm_chain)PF02142(MGS)PF02786(CPSase_L_D2)PF02787(CPSase_L_D3) | 5 | ILE A 281ILE A 259VAL A 278THR A 300ILE A 261 | None | 1.26A | 5lg3G-5dotA:undetectable | 5lg3G-5dotA:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5esc | HUPZ (Streptococcussp. 'group A') |
PF01243(Putative_PNPOx) | 5 | ILE A 64ILE A 110VAL A 17THR A 19ILE A 56 | None | 1.29A | 5lg3G-5escA:undetectable | 5lg3G-5escA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fl3 | PILI RETRACTIONPROTEIN PILT (Thermusthermophilus) |
PF00437(T2SSE) | 5 | ILE A 250ILE A 247THR A 139ASP A 242ILE A 273 | None | 1.17A | 5lg3G-5fl3A:undetectable | 5lg3G-5fl3A:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fof | LEUCYL-TRNASYNTHETASE (Plasmodiumknowlesi) |
no annotation | 5 | ILE A 314ILE A 377VAL A 277THR A 421ILE A 433 | None | 1.25A | 5lg3G-5fofA:undetectable | 5lg3G-5fofA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fqe | BETA-N-ACETYLGALACTOSAMINIDASE (Clostridiumperfringens) |
PF13320(DUF4091) | 5 | ILE A 338ILE A 281ASP A 260TRP A 262ILE A 267 | None | 1.22A | 5lg3G-5fqeA:undetectable | 5lg3G-5fqeA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g6r | IMINE REDUCTASE (Aspergillusoryzae) |
PF03446(NAD_binding_2) | 5 | ILE A 63ILE A 5VAL A 89THR A 87ILE A 145 | None | 1.06A | 5lg3G-5g6rA:undetectable | 5lg3G-5g6rA:24.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hd2 | PARASPORAL CRYSTALPROTEIN (Bacillusthuringiensis) |
PF03318(ETX_MTX2) | 5 | ILE A 183VAL A 254THR A 94ASN A 137GLU A 113 | None | 1.11A | 5lg3G-5hd2A:undetectable | 5lg3G-5hd2A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihy | UNCHARACTERIZEDPROTEIN (Bacillussubtilis) |
PF01966(HD) | 5 | ILE A 97ILE A 94VAL A 57THR A 53ASP A 89 | None | 1.14A | 5lg3G-5ihyA:undetectable | 5lg3G-5ihyA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tqr | POLYCOMB PROTEIN EED (Chaetomiumthermophilum) |
PF00400(WD40) | 5 | ILE A 67ILE A 87THR A 60ASN A 95ILE A 113 | None | 1.27A | 5lg3G-5tqrA:undetectable | 5lg3G-5tqrA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2j | RNAP2 (Escherichiavirus N4) |
no annotation | 5 | ILE B 323ILE B 269VAL B 318THR B 314ASN B 285 | None | 1.28A | 5lg3G-6c2jB:0.7 | 5lg3G-6c2jB:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cpb | CARBON MONOXIDEOXIDATION SYSTEMTRANSCRIPTIONREGULATOR COOA-1 (Carboxydothermushydrogenoformans) |
no annotation | 5 | ILE A 78VAL A 49THR A 98GLU A 27ILE A 106 | None | 1.27A | 5lg3G-6cpbA:undetectable | 5lg3G-6cpbA:13.36 |