SIMILAR PATTERNS OF AMINO ACIDS FOR 5LBT_A_6T0A303_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aog TRYPANOTHIONE
REDUCTASE

(Trypanosoma
cruzi) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 PHE A 123
ILE A  35
PHE A 115
GLY A  14
GLY A  17
 None
FAD  A 492 ( 4.6A)
None
FAD  A 492 (-3.3A)
None
 1.08A 5lbtA-1aogA:
4.0
5lbtB-1aogA:
3.9		 5lbtA-1aogA:
18.24
5lbtB-1aogA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7u ADSORPTION PROTEIN
P2

(Salmonella
virus PRD1) 		PF09214
(Prd1-P2) 		5 PHE A 369
ILE A 370
TRP A 410
GLY A 374
GLY A 373
 None
None
None
None
ACT  A 561 ( 4.2A)
 1.44A 5lbtA-1n7uA:
undetectable
5lbtB-1n7uA:
undetectable		 5lbtA-1n7uA:
17.41
5lbtB-1n7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC

(Klebsiella
pneumoniae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 ILE A  89
PHE A 164
GLY A  84
GLY A  82
MET A 122
 None
 1.22A 5lbtA-1ozhA:
2.2
5lbtB-1ozhA:
2.2		 5lbtA-1ozhA:
20.21
5lbtB-1ozhA:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qbg NAD(P)H
DEHYDROGENASE
[QUINONE] 1

(Homo sapiens) 		PF02525
(Flavodoxin_2) 		5 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
 FAD  A 501 (-4.5A)
FAD  A 501 (-3.9A)
FAD  A 501 (-4.0A)
None
FAD  A 501 (-4.9A)
 0.54A 5lbtA-1qbgA:
32.8
5lbtB-1qbgA:
32.2		 5lbtA-1qbgA:
43.18
5lbtB-1qbgA:
43.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdq CATHEPSIN B

(Bos taurus) 		PF00112
(Peptidase_C1) 		5 PHE A 231
ILE A 242
PHE A 180
TRP A 225
GLY A 198
 None
None
None
None
074  A 254 (-4.7A)
 1.49A 5lbtA-1qdqA:
undetectable
5lbtB-1qdqA:
undetectable		 5lbtA-1qdqA:
22.91
5lbtB-1qdqA:
22.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qrd QUINONE-REDUCTASE

(Rattus rattus) 		PF02525
(Flavodoxin_2) 		5 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
 DQN  A 276 ( 3.6A)
CBD  A 275 ( 3.7A)
FAD  A 274 (-3.7A)
CBD  A 275 ( 4.4A)
None
 0.47A 5lbtA-1qrdA:
29.5
5lbtB-1qrdA:
29.1		 5lbtA-1qrdA:
45.25
5lbtB-1qrdA:
45.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sp4 CATHEPSIN B

(Bos taurus) 		PF00112
(Peptidase_C1) 		5 PHE B 231
ILE B 242
PHE B 180
TRP B 225
GLY B 198
 None
None
None
None
EP2  B  48 (-3.6A)
 1.47A 5lbtA-1sp4B:
undetectable
5lbtB-1sp4B:
undetectable		 5lbtA-1sp4B:
21.67
5lbtB-1sp4B:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1typ TRYPANOTHIONE
REDUCTASE

(Crithidia
fasciculata) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 PHE A 122
ILE A  34
PHE A 114
GLY A  13
GLY A  16
 None
FAD  A 493 ( 4.8A)
None
FAD  A 493 (-3.2A)
None
 1.05A 5lbtA-1typA:
undetectable
5lbtB-1typA:
undetectable		 5lbtA-1typA:
20.21
5lbtB-1typA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0k OXIDOREDUCTASE

(Brevibacterium
sterolicum) 		PF01565
(FAD_binding_4)
PF09129
(Chol_subst-bind) 		5 ILE A 476
GLY A 435
GLY A 434
MET A 533
GLU A 551
 None
None
None
None
CAC  A 705 ( 4.8A)
 1.39A 5lbtA-2i0kA:
undetectable
5lbtB-2i0kA:
undetectable		 5lbtA-2i0kA:
18.48
5lbtB-2i0kA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lf8 TRANSCRIPTION FACTOR
ETV6

(Mus musculus) 		PF00178
(Ets) 		5 PHE A 415
ILE A 402
PHE A 364
TYR A 387
GLU A 434
 None
 1.44A 5lbtA-2lf8A:
undetectable
5lbtB-2lf8A:
undetectable		 5lbtA-2lf8A:
19.17
5lbtB-2lf8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4j AEROBIC
GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF01266
(DAO)
PF16901
(DAO_C) 		5 PHE A  87
PHE A 257
GLY A  51
GLY A  52
TYR A  55
 None
None
None
None
13P  A1968 (-4.6A)
 1.33A 5lbtA-2r4jA:
undetectable
5lbtB-2r4jA:
undetectable		 5lbtA-2r4jA:
19.57
5lbtB-2r4jA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdl STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00565
(SNase)
PF00567
(TUDOR) 		5 ILE A 796
GLY A 829
GLY A 827
TYR A 853
GLU A 833
 None
 1.44A 5lbtA-3bdlA:
undetectable
5lbtB-3bdlA:
undetectable		 5lbtA-3bdlA:
17.68
5lbtB-3bdlA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmg PUTATIVE
BETA-GALACTOSIDASE

(Bacteroides
fragilis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		5 PHE A  51
ILE A  84
PHE A  49
GLY A 171
GLY A 172
 None
None
MPD  A 802 (-4.2A)
None
None
 1.04A 5lbtA-3cmgA:
undetectable
5lbtB-3cmgA:
undetectable		 5lbtA-3cmgA:
17.54
5lbtB-3cmgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dea CUTINASE

(Colletotrichum
gloeosporioides) 		PF01083
(Cutinase) 		5 ILE A 175
PHE A 118
GLY A 134
GLY A 133
TYR A  51
 None
 1.29A 5lbtA-3deaA:
4.7
5lbtB-3deaA:
4.8		 5lbtA-3deaA:
23.94
5lbtB-3deaA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdu PUTATIVE
THIOESTERASE

(Syntrophus
aciditrophicus) 		PF03061
(4HBT) 		5 PHE A  45
ILE A  69
PHE A 118
GLY A  63
GLY A  62
 None
 1.30A 5lbtA-3hduA:
undetectable
5lbtB-3hduA:
undetectable		 5lbtA-3hduA:
23.32
5lbtB-3hduA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		5 PHE A 198
ILE A 235
GLY A 630
GLY A 629
TYR A 674
 None
 1.37A 5lbtA-3i04A:
4.8
5lbtB-3i04A:
4.7		 5lbtA-3i04A:
16.98
5lbtB-3i04A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl4 SIGNAL RECOGNITION
54 KDA PROTEIN

(Sulfolobus
solfataricus) 		PF00448
(SRP54)
PF02881
(SRP54_N)
PF02978
(SRP_SPB) 		5 ILE A 291
PHE A 282
GLY A 254
GLY A 253
MET A 247
 None
 1.40A 5lbtA-3kl4A:
2.4
5lbtB-3kl4A:
undetectable		 5lbtA-3kl4A:
19.86
5lbtB-3kl4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Archaeoglobus
fulgidus) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		5 ILE A 309
PHE A 212
TRP A 351
GLY A 312
GLY A 313
 None
 1.43A 5lbtA-3mm5A:
2.4
5lbtB-3mm5A:
2.4		 5lbtA-3mm5A:
18.91
5lbtB-3mm5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzp ARGININE
DECARBOXYLASE

(Campylobacter
jejuni) 		PF02784
(Orn_Arg_deC_N) 		5 PHE A  66
ILE A  62
GLY A 273
GLY A 272
ASN A 270
 None
None
PLP  A 701 (-3.5A)
PLP  A 701 ( 4.2A)
None
 1.42A 5lbtA-3nzpA:
undetectable
5lbtB-3nzpA:
undetectable		 5lbtA-3nzpA:
17.50
5lbtB-3nzpA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omn CYTOCHROME C
OXIDASE, AA3 TYPE,
SUBUNIT I

(Rhodobacter
sphaeroides) 		PF00115
(COX1) 		5 PHE A 295
ILE A 363
PHE A 387
GLY A 395
GLY A 394
 None
HEA  A   2 ( 4.4A)
None
HEA  A   2 (-3.4A)
None
 1.46A 5lbtA-3omnA:
undetectable
5lbtB-3omnA:
undetectable		 5lbtA-3omnA:
18.84
5lbtB-3omnA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfo PUTATIVE
ACETYLORNITHINE
DEACETYLASE

(Rhodopseudomonas
palustris) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		5 ILE A 111
PHE A  30
GLY A 146
GLY A 147
MET A 151
 None
EDO  A 504 (-4.8A)
None
None
None
 1.41A 5lbtA-3pfoA:
undetectable
5lbtB-3pfoA:
undetectable		 5lbtA-3pfoA:
19.91
5lbtB-3pfoA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyr ECHA16_2

(Mycobacterium
avium) 		PF00378
(ECH_1) 		5 PHE A  36
PHE A  37
TRP A  83
GLY A 102
GLY A 101
 None
None
None
None
EDO  A 250 ( 4.2A)
 1.49A 5lbtA-3qyrA:
undetectable
5lbtB-3qyrA:
undetectable		 5lbtA-3qyrA:
20.82
5lbtB-3qyrA:
20.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]

(Homo sapiens) 		PF02525
(Flavodoxin_2) 		7 TRP A 105
GLY A 149
GLY A 150
MET A 154
TYR A 155
ASN A 161
GLU A 193
 FAD  A 232 ( 4.3A)
FAD  A 232 (-3.6A)
FAD  A 232 (-3.6A)
None
FAD  A 232 (-4.6A)
None
FAD  A 232 ( 3.1A)
 0.10A 5lbtA-3te7A:
39.1
5lbtB-3te7A:
38.8		 5lbtA-3te7A:
99.56
5lbtB-3te7A:
99.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsy FUSION PROTEIN
4-COUMARATE--COA
LIGASE 1,
RESVERATROL SYNTHASE

(Arabidopsis
thaliana;
Vitis vinifera) 		PF00195
(Chal_sti_synt_N)
PF00501
(AMP-binding)
PF02797
(Chal_sti_synt_C)
PF13193
(AMP-binding_C) 		5 PHE A 852
ILE A 841
PHE A 802
GLY A 893
GLY A 892
 None
 1.13A 5lbtA-3tsyA:
3.1
5lbtB-3tsyA:
3.9		 5lbtA-3tsyA:
12.64
5lbtB-3tsyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wtb PUTATIVE
OXIDOREDUCTASE

(Gluconobacter
oxydans) 		PF13561
(adh_short_C2) 		5 ILE A 134
PHE A  28
GLY A 130
GLY A 131
MET A 127
 None
 1.38A 5lbtA-3wtbA:
6.2
5lbtB-3wtbA:
6.2		 5lbtA-3wtbA:
26.04
5lbtB-3wtbA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ehc PE-PGRS FAMILY
PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 5 PHE A  48
ILE A  23
PHE A  53
GLY A  28
GLY A  27
 None
None
EDO  A 308 (-4.1A)
EDO  A 303 (-3.4A)
None
 1.34A 5lbtA-4ehcA:
undetectable
5lbtB-4ehcA:
undetectable		 5lbtA-4ehcA:
22.08
5lbtB-4ehcA:
22.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gi5 QUINONE REDUCTASE

(Klebsiella
pneumoniae) 		PF02525
(Flavodoxin_2) 		5 TRP A 102
GLY A 154
GLY A 155
TYR A 160
ASN A 166
 FAD  A 301 (-4.1A)
FAD  A 301 (-3.6A)
FAD  A 301 (-3.5A)
FAD  A 301 (-4.7A)
None
 0.36A 5lbtA-4gi5A:
30.4
5lbtB-4gi5A:
30.0		 5lbtA-4gi5A:
37.63
5lbtB-4gi5A:
37.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hh2 TRANSCRIPTIONAL
REGULATOR, PPSR

(Rhodobacter
sphaeroides) 		PF13188
(PAS_8)
PF13426
(PAS_9) 		5 PHE A 317
ILE A 314
GLY A 292
TYR A 274
ASN A 294
 None
 1.41A 5lbtA-4hh2A:
undetectable
5lbtB-4hh2A:
undetectable		 5lbtA-4hh2A:
19.40
5lbtB-4hh2A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i04 CATHEPSIN B-LIKE
PEPTIDASE (C01
FAMILY)

(Schistosoma
mansoni) 		PF00112
(Peptidase_C1)
PF08127
(Propeptide_C1) 		5 PHE A 302
ILE A 313
PHE A 251
TRP A 296
GLY A 269
 None
 1.38A 5lbtA-4i04A:
undetectable
5lbtB-4i04A:
undetectable		 5lbtA-4i04A:
20.71
5lbtB-4i04A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i05 CATHEPSIN B-LIKE
PEPTIDASE (C01
FAMILY)

(Schistosoma
mansoni) 		PF00112
(Peptidase_C1) 		5 PHE A 302
ILE A 313
PHE A 251
TRP A 296
GLY A 269
 None
 1.50A 5lbtA-4i05A:
undetectable
5lbtB-4i05A:
undetectable		 5lbtA-4i05A:
21.17
5lbtB-4i05A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5b COBALAMIN
BIOSYNTHESIS PROTEIN
CBIM

(Caldanaerobacter
subterraneus) 		PF01891
(CbiM) 		5 PHE A 188
ILE A  60
GLY A 195
TYR A 144
ASN A 148
 None
None
None
HEZ  A 305 (-3.7A)
None
 1.37A 5lbtA-4m5bA:
undetectable
5lbtB-4m5bA:
undetectable		 5lbtA-4m5bA:
23.40
5lbtB-4m5bA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7o GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE,
PUTATIVE

(Bacillus
anthracis) 		PF03009
(GDPD) 		5 ILE A 282
TRP A 212
GLY A 250
MET A 267
TYR A 266
 None
 1.37A 5lbtA-4r7oA:
undetectable
5lbtB-4r7oA:
undetectable		 5lbtA-4r7oA:
22.97
5lbtB-4r7oA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rih GLYCOSYL TRANSFERASE
HOMOLOG,GLYCOSYL
TRANSFERASE

(Streptomyces
cyanogenus;
Streptomyces
fradiae) 		PF06722
(DUF1205) 		5 ILE A 173
PHE A 170
GLY A 114
GLY A 113
TYR A 131
 None
 1.26A 5lbtA-4rihA:
4.8
5lbtB-4rihA:
4.8		 5lbtA-4rihA:
21.03
5lbtB-4rihA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlt (3R)-HYDROXYACYL-ACP
DEHYDRATASE SUBUNIT
HADA
(3R)-HYDROXYACYL-ACP
DEHYDRATASE SUBUNIT
HADB

(Mycobacterium
tuberculosis) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		5 ILE B 120
TRP A  38
GLY B  67
GLY B  66
TYR B  20
 None
 1.37A 5lbtA-4rltB:
undetectable
5lbtB-4rltB:
undetectable		 5lbtA-4rltB:
21.74
5lbtB-4rltB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wh0 PUTATIVE HYDROLASE

(Pseudomonas
aeruginosa) 		PF00857
(Isochorismatase) 		5 PHE A 166
ILE A  46
GLY A 188
GLY A 189
ASN A  38
 None
 1.42A 5lbtA-4wh0A:
4.3
5lbtB-4wh0A:
4.4		 5lbtA-4wh0A:
20.29
5lbtB-4wh0A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yyf BETA-N-ACETYLHEXOSAM
INIDASE

(Mycolicibacterium
smegmatis) 		PF00933
(Glyco_hydro_3) 		5 ILE A 160
PHE A 197
GLY A 129
GLY A 130
GLU A 127
 ACT  A 402 ( 4.2A)
None
None
None
None
 1.32A 5lbtA-4yyfA:
undetectable
5lbtB-4yyfA:
undetectable		 5lbtA-4yyfA:
22.68
5lbtB-4yyfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hrm HALOALKYLPHOSPHORUS
HYDROLASE

(Sphingobium sp.
TCM1) 		no annotation 5 PHE A 433
ILE A 499
GLY A 495
GLY A 496
GLU A  98
 None
 1.16A 5lbtA-5hrmA:
undetectable
5lbtB-5hrmA:
undetectable		 5lbtA-5hrmA:
17.13
5lbtB-5hrmA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbf METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER (TLPC)

(Helicobacter
pylori) 		no annotation 5 ILE A 186
PHE A 267
TRP A 278
GLY A 205
TYR A 239
 None
 1.39A 5lbtA-5wbfA:
undetectable
5lbtB-5wbfA:
undetectable		 5lbtA-5wbfA:
22.81
5lbtB-5wbfA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis) 		no annotation 5 ILE A 150
PHE A  23
GLY A  72
GLY A  73
TYR A  56
 None
 1.40A 5lbtA-5ybaA:
undetectable
5lbtB-5ybaA:
undetectable		 5lbtA-5ybaA:
undetectable
5lbtB-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cqb CHALCONE SYNTHASE

(Piper
methysticum) 		no annotation 5 PHE A 266
ILE A 255
PHE A 216
GLY A 307
GLY A 306
 None
 1.16A 5lbtA-6cqbA:
undetectable
5lbtB-6cqbA:
undetectable		 5lbtA-6cqbA:
18.72
5lbtB-6cqbA:
18.72