SIMILAR PATTERNS OF AMINO ACIDS FOR 5L1F_C_6ZPC902_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASELARGE SUBUNIT (Desulfovibriodesulfuricans) |
PF00374(NiFeSe_Hases) | 4 | SER B 540PRO B 535SER B 362ASN B 364 | None | 1.12A | 5l1fC-1e3dB:undetectable | 5l1fC-1e3dB:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e4o | MALTODEXTRINPHOSPHORYLASE (Escherichiacoli) |
PF00343(Phosphorylase) | 4 | SER A 783TYR A 63SER A 639ASN A 449 | NoneNoneGLC A 998 (-4.9A)GLC A 998 (-3.3A) | 1.23A | 5l1fC-1e4oA:4.1 | 5l1fC-1e4oA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 4 | ASP A 134PRO A 135TYR A 289SER A 297 | None | 1.24A | 5l1fC-1fbwA:undetectable | 5l1fC-1fbwA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fob | BETA-1,4-GALACTANASE (Aspergillusaculeatus) |
PF07745(Glyco_hydro_53) | 4 | ASP A 181TYR A 215SER A 132ASN A 135 | None | 1.22A | 5l1fC-1fobA:2.3 | 5l1fC-1fobA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h14 | ENDO-1,4-BETA-XYLANASE (Pseudoalteromonashaloplanktis) |
PF01270(Glyco_hydro_8) | 4 | PRO A 141PHE A 191SER A 202ASN A 144 | None | 1.20A | 5l1fC-1h14A:undetectable | 5l1fC-1h14A:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hjv | CHITINASE-3 LIKEPROTEIN 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | PRO A 142TYR A 189PHE A 106SER A 95 | None | 1.23A | 5l1fC-1hjvA:undetectable | 5l1fC-1hjvA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i1q | ANTHRANILATESYNTHASE COMPONENT IANTHRANILATESYNTHASE COMPONENTII (Salmonellaenterica) |
PF00117(GATase)PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 4 | SER B 11ASP B 10PRO B 57SER A 427 | None | 1.16A | 5l1fC-1i1qB:3.5 | 5l1fC-1i1qB:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k8g | TELOMERE-BINDINGPROTEIN ALPHASUBUNIT (Sterkiella nova) |
PF02765(POT1) | 4 | SER A 249ASP A 247PHE A 253ASN A 215 | None | 1.24A | 5l1fC-1k8gA:undetectable | 5l1fC-1k8gA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5x | SURVIVAL PROTEIN E (Pyrobaculumaerophilum) |
PF01975(SurE) | 4 | SER A 106TYR A 192SER A 169ASN A 97 | None | 1.22A | 5l1fC-1l5xA:3.9 | 5l1fC-1l5xA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ljy | MGP-40 (Capra hircus) |
PF00704(Glyco_hydro_18) | 4 | PRO A 121TYR A 168PHE A 85SER A 74 | None | 1.14A | 5l1fC-1ljyA:2.3 | 5l1fC-1ljyA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mek | PROTEIN DISULFIDEISOMERASE (Homo sapiens) |
PF00085(Thioredoxin) | 4 | ASP A 92PRO A 96TYR A 77PHE A 87 | None | 1.24A | 5l1fC-1mekA:undetectable | 5l1fC-1mekA:9.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 37 KDASUBUNITACTIVATOR 1 95 KDASUBUNIT (Saccharomycescerevisiae) |
PF00004(AAA)PF08519(RFC1)PF08542(Rep_fac_C) | 4 | PRO A 589TYR A 581PHE A 587SER B 147 | None | 1.21A | 5l1fC-1sxjA:undetectable | 5l1fC-1sxjA:19.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ule | GALECTIN-2 (Coprinopsiscinerea) |
PF00337(Gal-bind_lectin) | 4 | SER A 130TYR A 80PHE A 39SER A 27 | None | 1.18A | 5l1fC-1uleA:undetectable | 5l1fC-1uleA:11.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3x | IRON-RESPONSIVEELEMENT BINDINGPROTEIN 1 (Homo sapiens) |
PF00330(Aconitase)PF00694(Aconitase_C) | 4 | PRO A 514TYR A 417SER A 138ASN A 133 | EDO A1002 ( 4.7A)NoneNoneEDO A1002 (-3.1A) | 1.11A | 5l1fC-2b3xA:undetectable | 5l1fC-2b3xA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1l | RESTRICTIONENDONUCLEASE (Bacillus firmus) |
PF13091(PLDc_2) | 4 | ASP A 142PHE A 3SER A 29ASN A 30 | None | 1.08A | 5l1fC-2c1lA:undetectable | 5l1fC-2c1lA:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1g | ACID PHOSPHATASE (Francisellatularensis) |
PF04185(Phosphoesterase) | 4 | PRO A 259TYR A 262SER A 298ASN A 299 | None | 1.24A | 5l1fC-2d1gA:undetectable | 5l1fC-2d1gA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3r | LECTIN ALPHA CHAIN (Cratyliaargentea) |
PF00139(Lectin_legB) | 4 | SER A 218ASP A 2PHE A 232SER A 94 | None | 1.17A | 5l1fC-2d3rA:undetectable | 5l1fC-2d3rA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) |
PF00139(Lectin_legB) | 4 | SER A 214ASP A 212TYR A 106PHE A 126 | GAL A 401 ( 3.1A)A2G A 400 (-4.9A)A2G A 400 ( 4.7A)A2G A 400 ( 3.8A) | 1.24A | 5l1fC-2e7tA:undetectable | 5l1fC-2e7tA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsn | PHOSPHODIESTERASE-NUCLEOTIDEPYROPHOSPHATASE (Xanthomonascitri) |
PF01663(Phosphodiest) | 4 | SER A 371PRO A 218TYR A 223SER A 88 | None | 1.17A | 5l1fC-2gsnA:undetectable | 5l1fC-2gsnA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i58 | SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF13416(SBP_bac_8) | 4 | PRO A 66TYR A 100SER A 245ASN A 114 | None | 1.14A | 5l1fC-2i58A:undetectable | 5l1fC-2i58A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i58 | SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF13416(SBP_bac_8) | 4 | PRO A 66TYR A 100SER A 317ASN A 114 | None | 0.64A | 5l1fC-2i58A:undetectable | 5l1fC-2i58A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i58 | SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF13416(SBP_bac_8) | 4 | PRO A 110TYR A 96SER A 245ASN A 114 | None | 1.12A | 5l1fC-2i58A:undetectable | 5l1fC-2i58A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivf | ETHYLBENZENEDEHYDROGENASEALPHA-SUBUNIT (Aromatoleumaromaticum) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | SER A 263TYR A 443PHE A 267ASN A 668 | SF4 A1984 ( 4.4A)NoneNoneNone | 1.18A | 5l1fC-2ivfA:undetectable | 5l1fC-2ivfA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j4l | URIDYLATE KINASE (Sulfolobussolfataricus) |
PF00696(AA_kinase) | 4 | PRO A 149TYR A 145SER A 8ASN A 140 | NoneNoneUTP A1227 (-3.6A)None | 1.12A | 5l1fC-2j4lA:3.0 | 5l1fC-2j4lA:14.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kpy | MAJOR POLLENALLERGEN ART V 1 (Artemisiavulgaris) |
PF00304(Gamma-thionin) | 4 | ASP A 23TYR A 13SER A 78ASN A 19 | None | 1.22A | 5l1fC-2kpyA:undetectable | 5l1fC-2kpyA:8.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l3w | PHYCOBILISOME RODLINKER POLYPEPTIDE (Synechococcuselongatus) |
PF00427(PBS_linker_poly) | 4 | PRO A 131TYR A 121PHE A 54SER A 61 | None | 1.25A | 5l1fC-2l3wA:undetectable | 5l1fC-2l3wA:10.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nxg | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Aquifexaeolicus) |
PF00793(DAHP_synth_1) | 4 | SER A1043ASP A1081PRO A1101SER A1232 | PEP A1268 (-3.6A)PEP A1268 ( 4.5A)PEP A1268 (-4.0A)None | 1.20A | 5l1fC-2nxgA:undetectable | 5l1fC-2nxgA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nya | PERIPLASMIC NITRATEREDUCTASE (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | ASP A 171PHE A 173SER A 197ASN A 198 | None | 1.01A | 5l1fC-2nyaA:undetectable | 5l1fC-2nyaA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po4 | VIRION RNAPOLYMERASE (Escherichiavirus N4) |
no annotation | 4 | PRO A1066PHE A 591SER A 604ASN A 600 | None | 1.21A | 5l1fC-2po4A:undetectable | 5l1fC-2po4A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qri | H-2 CLASS IHISTOCOMPATIBILITYANTIGEN K-B ALPHACHAIN, BETA-2MICROGLOBULIN,OVALBUMIN-DERIVEDPEPTIDE (Mus musculus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | ASP A 212PRO A 210TYR A 209SER A 4 | None | 1.21A | 5l1fC-2qriA:undetectable | 5l1fC-2qriA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r0s | CHROMATINSTRUCTURE-REMODELINGCOMPLEX PROTEIN RSC4 (Saccharomycescerevisiae) |
PF00439(Bromodomain) | 4 | PRO A 84PHE A 80SER A 138ASN A 134 | None | 1.11A | 5l1fC-2r0sA:2.8 | 5l1fC-2r0sA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r0v | CHROMATINSTRUCTURE-REMODELINGCOMPLEX PROTEIN RSC4 (Saccharomycescerevisiae) |
PF00439(Bromodomain) | 4 | PRO A 84PHE A 80SER A 138ASN A 134 | ALY A 25 ( 4.2A)NoneNoneALY A 25 ( 3.3A) | 1.06A | 5l1fC-2r0vA:undetectable | 5l1fC-2r0vA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uut | RNA-DIRECTED RNAPOLYMERASE (Sapporo virus) |
PF00680(RdRP_1) | 4 | ASP A 188PRO A 120TYR A 286SER A 281 | None | 1.10A | 5l1fC-2uutA:undetectable | 5l1fC-2uutA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wgy | CYTOCHROME P450 130 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | SER A 67ASP A 93PRO A 94SER A 348 | HEM A 450 ( 4.8A)NoneNoneHEM A 450 (-3.4A) | 1.17A | 5l1fC-2wgyA:undetectable | 5l1fC-2wgyA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzf | GLUCOSYLTRANSFERASE (Legionellapneumophila) |
PF16849(Glyco_transf_88) | 4 | SER A 519PRO A 522TYR A 440SER A 229 | UDP A1525 (-2.8A)NoneNoneUDP A1525 (-2.8A) | 1.22A | 5l1fC-2wzfA:2.2 | 5l1fC-2wzfA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn0 | TRANSCRIPTION FACTORTAU 55 KDA SUBUNIT (Saccharomycescerevisiae) |
PF00300(His_Phos_1) | 4 | ASP A 31PRO A 103TYR A 94SER A 15 | None | 1.20A | 5l1fC-2yn0A:3.1 | 5l1fC-2yn0A:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zoa | PHOSPHOHYDROLASE (Klebsiellaaerogenes) |
PF00149(Metallophos) | 4 | ASP A 168PRO A 169SER A 198ASN A 196 | None | 1.16A | 5l1fC-2zoaA:2.3 | 5l1fC-2zoaA:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asp | CAPSID PROTEIN (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 4 | PRO A 404TYR A 406PHE A 326SER A 245 | None | 1.13A | 5l1fC-3aspA:undetectable | 5l1fC-3aspA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bdi | UNCHARACTERIZEDPROTEIN TA0194 (Thermoplasmaacidophilum) |
PF00561(Abhydrolase_1)PF12146(Hydrolase_4) | 4 | SER A 39ASP A 62TYR A 92PHE A 7 | None | 1.16A | 5l1fC-3bdiA:3.3 | 5l1fC-3bdiA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fhc | ATP-DEPENDENT RNAHELICASE DDX19BNUCLEAR PORE COMPLEXPROTEIN NUP214 (Homo sapiens) |
PF00270(DEAD)PF12894(ANAPC4_WD40) | 4 | SER B 280ASP A 76PRO A 77SER B 274 | None | 1.14A | 5l1fC-3fhcB:undetectable | 5l1fC-3fhcB:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9f | PUTATIVE TYPE 11METHYLTRANSFERASE (Sulfolobussolfataricus) |
PF08241(Methyltransf_11) | 4 | PRO A 162TYR A 23PHE A 167ASN A 97 | None | 0.96A | 5l1fC-3i9fA:2.9 | 5l1fC-3i9fA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-PROCESSINGFACTOR 19 (Schizosaccharomycespombe) |
PF08606(Prp19) | 4 | SER S 4PRO S 10SER S 19ASN S 21 | None | 1.14A | 5l1fC-3jb9S:undetectable | 5l1fC-3jb9S:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgx | PUTATIVE P450MONOOXYGENASE (Amycolatopsisbalhimycina) |
PF00067(p450) | 4 | ASP A 316PRO A 317PHE A 320SER A 280 | None | 1.10A | 5l1fC-3mgxA:undetectable | 5l1fC-3mgxA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzq | BIOSYNTHETICARGININEDECARBOXYLASE (Escherichiacoli) |
PF02784(Orn_Arg_deC_N) | 4 | ASP A 64PRO A 63TYR A 48SER A 141 | None | 1.02A | 5l1fC-3nzqA:undetectable | 5l1fC-3nzqA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o82 | PEPTIDE ARYLATIONENZYME (Acinetobacterbaumannii) |
PF00501(AMP-binding) | 4 | SER A 366ASP A 367PRO A 393TYR A 394 | None | 1.23A | 5l1fC-3o82A:4.2 | 5l1fC-3o82A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ofl | L1 (Alphapapillomavirus7) |
PF00500(Late_protein_L1) | 4 | SER A 398PRO A 441TYR A 442ASN A 396 | None | 1.02A | 5l1fC-3oflA:undetectable | 5l1fC-3oflA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3on6 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF06824(Glyco_hydro_125) | 4 | SER A 265PRO A 395PHE A 333SER A 260 | None | 1.23A | 5l1fC-3on6A:undetectable | 5l1fC-3on6A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p2c | PUTATIVE GLYCOSYLHYDROLASE (Bacteroidesovatus) |
PF06824(Glyco_hydro_125) | 4 | SER A 271PRO A 401PHE A 339SER A 266 | None | 1.24A | 5l1fC-3p2cA:undetectable | 5l1fC-3p2cA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ppx | VON WILLEBRANDFACTOR (Homo sapiens) |
PF00092(VWA) | 4 | PRO A1632PHE A1654SER A1506ASN A1610 | None | 1.16A | 5l1fC-3ppxA:5.8 | 5l1fC-3ppxA:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ptk | BETA-GLUCOSIDASEOS4BGLU12 (Oryza sativa) |
PF00232(Glyco_hydro_1) | 4 | SER A 363ASP A 397SER A 451ASN A 452 | None | 1.15A | 5l1fC-3ptkA:undetectable | 5l1fC-3ptkA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pyw | S-LAYER PROTEIN SAP (Bacillusanthracis) |
PF00395(SLH) | 4 | ASP A 7PRO A 6PHE A 5ASN A 30 | None | 1.14A | 5l1fC-3pywA:undetectable | 5l1fC-3pywA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qt3 | PUTATIVEUNCHARACTERIZEDPROTEIN CPE0426 (Clostridiumperfringens) |
PF06824(Glyco_hydro_125) | 4 | SER A 308PRO A 230PHE A 234SER A 68 | None | 1.24A | 5l1fC-3qt3A:undetectable | 5l1fC-3qt3A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT LNADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli) |
no annotation | 4 | ASP N 229PRO N 228TYR N 300SER L 597 | None | 1.20A | 5l1fC-3rkoN:2.7 | 5l1fC-3rkoN:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5t | PUTATIVEGLYCOSYLTRANSFERASE (Streptomyceshygroscopicus) |
PF00982(Glyco_transf_20) | 4 | SER A 388PRO A 393SER A 380ASN A 386 | None | 1.18A | 5l1fC-3t5tA:undetectable | 5l1fC-3t5tA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vr5 | V-TYPE SODIUM ATPASECATALYTIC SUBUNIT AV-TYPE SODIUM ATPASESUBUNIT B (Enterococcushirae) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N)PF16886(ATP-synt_ab_Xtn) | 4 | PRO D 225TYR D 253SER A 56ASN D 112 | None | 1.17A | 5l1fC-3vr5D:undetectable | 5l1fC-3vr5D:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w0w | T36-5 TCR BETA CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | ASP E 38PRO E 39SER E 82ASN E 84 | None | 1.18A | 5l1fC-3w0wE:undetectable | 5l1fC-3w0wE:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1g | DNA LIGASE 4 (Homo sapiens) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | ASP A 441PRO A 440TYR A 438SER A 292 | NoneNoneNoneSO4 A 703 (-2.3A) | 1.26A | 5l1fC-3w1gA:undetectable | 5l1fC-3w1gA:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zg8 | PENICILLIN-BINDINGPROTEIN 4 (Listeriamonocytogenes) |
PF00905(Transpeptidase)PF00912(Transgly) | 4 | SER B 394PRO B 398TYR B 504SER B 623 | AIX B 800 (-0.2A)NoneNoneAIX B 800 (-2.4A) | 1.20A | 5l1fC-3zg8B:undetectable | 5l1fC-3zg8B:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyv | AOX3 (Mus musculus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 4 | PRO A1156TYR A1141SER A1188ASN A1254 | None | 1.11A | 5l1fC-3zyvA:undetectable | 5l1fC-3zyvA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4acz | ENDO-ALPHA-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF16317(Glyco_hydro_99) | 4 | ASP B 129TYR B 175SER B 99ASN B 48 | None | 1.22A | 5l1fC-4aczB:undetectable | 5l1fC-4aczB:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ag9 | GLUCOSAMINE-6-PHOSPHATEN-ACETYLTRANSFERASE (Caenorhabditiselegans) |
PF00583(Acetyltransf_1) | 4 | ASP A 20PRO A 19SER A 78ASN A 77 | None | 1.13A | 5l1fC-4ag9A:undetectable | 5l1fC-4ag9A:12.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ay1 | CHITINASE-3-LIKEPROTEIN 2 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | PRO A 147TYR A 195PHE A 111SER A 100 | None | 1.13A | 5l1fC-4ay1A:3.3 | 5l1fC-4ay1A:19.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzi | SEC23P (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 4 | PRO A 709PHE A 660SER A 621ASN A 620 | None | 1.19A | 5l1fC-4bziA:4.2 | 5l1fC-4bziA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4el8 | GLYCOSIDE HYDROLASEFAMILY 48 (Caldicellulosiruptorbescii) |
PF02011(Glyco_hydro_48) | 4 | ASP A 131PRO A 132TYR A 290SER A 298 | None | 1.24A | 5l1fC-4el8A:undetectable | 5l1fC-4el8A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fgm | AMINOPEPTIDASE NFAMILY PROTEIN (Idiomarinaloihiensis) |
PF05299(Peptidase_M61)PF13180(PDZ_2) | 4 | SER A 93ASP A 91PHE A 46SER A 40 | NoneNoneNoneMAE A 601 ( 3.7A) | 1.21A | 5l1fC-4fgmA:undetectable | 5l1fC-4fgmA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fus | RTX TOXINS ANDRELATED CA2+-BINDINGPROTEIN (Hahellachejuensis) |
PF02011(Glyco_hydro_48) | 4 | ASP A 160PRO A 161TYR A 321SER A 329 | NoneEDO A 819 ( 4.7A)NoneOHI A 352 ( 4.4A) | 1.22A | 5l1fC-4fusA:undetectable | 5l1fC-4fusA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1i | PROTEIN PRGH (Salmonellaenterica) |
PF09480(PrgH) | 4 | PRO A 256TYR A 285SER A 233ASN A 229 | None | 1.07A | 5l1fC-4g1iA:undetectable | 5l1fC-4g1iA:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h6q | PROLINEDEHYDROGENASE (Deinococcusradiodurans) |
PF01619(Pro_dh) | 4 | SER A 96ASP A 135TYR A 288ASN A 58 | NoneTFB A2002 ( 3.7A)TFB A2002 (-4.7A)None | 1.16A | 5l1fC-4h6qA:undetectable | 5l1fC-4h6qA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irx | SUGAR ABCTRANSPORTER,PERIPLASMICSUGAR-BINDINGPROTEIN (Caulobactervibrioides) |
PF13407(Peripla_BP_4) | 4 | SER A 174PHE A 52SER A 203ASN A 168 | INS A 401 (-2.5A)NoneINS A 401 (-2.7A)INS A 401 (-3.8A) | 1.17A | 5l1fC-4irxA:15.3 | 5l1fC-4irxA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jc8 | HOPS COMPONENT VPS33 (Chaetomiumthermophilum) |
PF00995(Sec1) | 4 | ASP A 510PRO A 511TYR A 516SER A 322 | None | 1.24A | 5l1fC-4jc8A:3.0 | 5l1fC-4jc8A:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnm | CHITINASE A (Cycas revoluta) |
PF00704(Glyco_hydro_18) | 4 | PRO A 121TYR A 174PHE A 85SER A 73 | None | 1.25A | 5l1fC-4mnmA:3.4 | 5l1fC-4mnmA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqr | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 4 | ASP A 318PRO A 319PHE A 322SER A 280 | None | 1.16A | 5l1fC-4oqrA:undetectable | 5l1fC-4oqrA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqs | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 4 | ASP A 318PRO A 319PHE A 322SER A 280 | None | 1.17A | 5l1fC-4oqsA:undetectable | 5l1fC-4oqsA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4owx | SOSS COMPLEX SUBUNITB1 (Homo sapiens) |
PF01336(tRNA_anti-codon) | 4 | SER B 109PRO B 111SER B 53ASN B 51 | None | 1.23A | 5l1fC-4owxB:undetectable | 5l1fC-4owxB:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oy2 | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 1TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 7 (Saccharomycescerevisiae) |
PF04658(TAFII55_N)PF12157(DUF3591) | 4 | TYR B 238PHE A 498SER A 639ASN A 645 | None | 1.22A | 5l1fC-4oy2B:undetectable | 5l1fC-4oy2B:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r33 | NOSL (Streptomycesactuosus) |
PF06968(BATS) | 4 | SER A 362ASP A 345PRO A 348TYR A 349 | None | 1.17A | 5l1fC-4r33A:2.5 | 5l1fC-4r33A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7q | SENSOR HISTIDINEKINASE (Vibrio cholerae) |
PF11884(DUF3404) | 4 | SER A 135PRO A 114TYR A 86PHE A 117 | None | 1.20A | 5l1fC-4r7qA:undetectable | 5l1fC-4r7qA:14.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgg | PUTATIVE PHAGESTRUCTURAL PROTEIN (Lactococcusphage 1358) |
no annotation | 4 | SER A 202ASP A 243PRO A 242PHE A 240 | NoneNoneNoneGN1 A 401 ( 4.3A) | 1.26A | 5l1fC-4rggA:undetectable | 5l1fC-4rggA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rpf | HOMOSERINE KINASE (Yersinia pestis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | SER A 94PRO A 178TYR A 287PHE A 294 | CIT A 401 (-3.6A)NoneNoneNone | 1.24A | 5l1fC-4rpfA:undetectable | 5l1fC-4rpfA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tnm | IMPORTIN SUBUNITALPHA (Arabidopsisthaliana) |
PF00514(Arm)PF01749(IBB)PF16186(Arm_3) | 4 | SER A 160PRO A 164TYR A 202PHE A 166 | None | 1.26A | 5l1fC-4tnmA:2.6 | 5l1fC-4tnmA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4we6 | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | SER A 55ASP A 33PRO A 34PHE A 108 | None | 1.25A | 5l1fC-4we6A:undetectable | 5l1fC-4we6A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zke | SUPERKILLER PROTEIN7 (Saccharomycescerevisiae) |
PF00009(GTP_EFTU) | 4 | ASP A 376PRO A 377TYR A 380ASN A 728 | ASP A 376 ( 0.6A)PRO A 377 ( 1.1A)TYR A 380 ( 1.3A)ASN A 728 ( 0.6A) | 1.02A | 5l1fC-4zkeA:4.6 | 5l1fC-4zkeA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3h | PROTEIN SCARECROWPROTEIN SHORT-ROOT (Arabidopsisthaliana) |
PF03514(GRAS) | 4 | SER A 317PRO A 322TYR A 323SER B 185 | None | 1.24A | 5l1fC-5b3hA:3.9 | 5l1fC-5b3hA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doo | PROTEIN LYSINEMETHYLTRANSFERASE 2 (Rickettsiatyphi) |
PF10119(MethyTransf_Reg)PF13847(Methyltransf_31) | 4 | SER A 253ASP A 251PHE A 147SER A 21 | None | 1.26A | 5l1fC-5dooA:undetectable | 5l1fC-5dooA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hk8 | PROBABLEPHEOPHORBIDASE (Arabidopsisthaliana) |
PF12697(Abhydrolase_6) | 4 | SER A 166PRO A 246PHE A 242SER A 174 | None | 0.75A | 5l1fC-5hk8A:3.5 | 5l1fC-5hk8A:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6z | SODIUM-DEPENDENTSEROTONINTRANSPORTER (Homo sapiens) |
PF00209(SNF) | 4 | SER A 336TYR A 176SER A 375ASN A 101 | None | 1.25A | 5l1fC-5i6zA:undetectable | 5l1fC-5i6zA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iry | DESMOCOLLIN-1 (Homo sapiens) |
PF00028(Cadherin) | 4 | SER A 254ASP A 245PRO A 218ASN A 278 | None CA A 607 (-2.1A)NoneNone | 1.21A | 5l1fC-5iryA:undetectable | 5l1fC-5iryA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kjo | ENDOGLUCANASE V-LIKEPROTEIN (Phanerochaetechrysosporium) |
no annotation | 4 | SER A 14PRO A 66TYR A 67ASN A 105 | None | 1.21A | 5l1fC-5kjoA:undetectable | 5l1fC-5kjoA:13.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1b | GLUTAMATE RECEPTOR2,GLUTAMATE RECEPTOR2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | ASP A 519TYR A 616SER A 788ASN A 791 | None | 0.87A | 5l1fC-5l1bA:46.0 | 5l1fC-5l1bA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1b | GLUTAMATE RECEPTOR2,GLUTAMATE RECEPTOR2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | SER A 516ASP A 519TYR A 616ASN A 791 | None | 1.00A | 5l1fC-5l1bA:46.0 | 5l1fC-5l1bA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5li8 | PUTATIVE CYTOCHROMEP450 126 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | ASP A 334PRO A 335PHE A 338SER A 298 | None | 1.20A | 5l1fC-5li8A:undetectable | 5l1fC-5li8A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lqd | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (Streptomycesvenezuelae) |
PF00982(Glyco_transf_20) | 4 | ASP A 262TYR A 310SER A 383ASN A 357 | None | 1.15A | 5l1fC-5lqdA:4.3 | 5l1fC-5lqdA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgv | PHENYLALANINE--TRNALIGASE,MITOCHONDRIAL (Homo sapiens) |
PF01409(tRNA-synt_2d)PF03147(FDX-ACB) | 4 | SER A 149ASP A 292PRO A 291TYR A 289 | None | 1.24A | 5l1fC-5mgvA:undetectable | 5l1fC-5mgvA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oj7 | NAD-DEPENDENTPROTEIN DEACYLASE (Xenopustropicalis) |
no annotation | 4 | SER A 65PRO A 71PHE A 115ASN A 143 | None | 1.24A | 5l1fC-5oj7A:undetectable | 5l1fC-5oj7A:6.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 4 | SER A 516ASP A 519PRO A 520TYR A 616 | None | 0.72A | 5l1fC-5welA:55.6 | 5l1fC-5welA:78.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | SER A 516ASP A 519PRO A 520TYR A 616 | None | 0.79A | 5l1fC-5weoA:51.8 | 5l1fC-5weoA:77.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xep | CHITINASE-3-LIKEPROTEIN 1 (Mus musculus) |
no annotation | 4 | PRO A 143TYR A 190PHE A 107SER A 96 | None | 1.03A | 5l1fC-5xepA:2.7 | 5l1fC-5xepA:7.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | DNA-DEPENDENTPROTEIN KINASECATALYTIC SUBUNIT (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08163(NUC194) | 4 | SER C3432ASP C3435PHE C3382ASN C3430 | None | 1.21A | 5l1fC-5y3rC:undetectable | 5l1fC-5y3rC:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yj6 | DOCKERIN TYPE IREPEAT-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 4 | ASP A 165PRO A 166TYR A 317ASN A 296 | None | 1.25A | 5l1fC-5yj6A:undetectable | 5l1fC-5yj6A:8.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 8fab | IGG1-LAMBDA HIL FAB(HEAVY CHAIN)IGG1-LAMBDA HIL FAB(LIGHT CHAIN) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | ASP B 99PRO B 100TYR A 48PHE B 108 | None | 1.24A | 5l1fC-8fabB:undetectable | 5l1fC-8fabB:15.05 |