SIMILAR PATTERNS OF AMINO ACIDS FOR 5L1F_C_6ZPC902

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3d [NIFE] HYDROGENASE
LARGE SUBUNIT


(Desulfovibrio
desulfuricans)
PF00374
(NiFeSe_Hases)
4 SER B 540
PRO B 535
SER B 362
ASN B 364
None
1.12A 5l1fC-1e3dB:
undetectable
5l1fC-1e3dB:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4o MALTODEXTRIN
PHOSPHORYLASE


(Escherichia
coli)
PF00343
(Phosphorylase)
4 SER A 783
TYR A  63
SER A 639
ASN A 449
None
None
GLC  A 998 (-4.9A)
GLC  A 998 (-3.3A)
1.23A 5l1fC-1e4oA:
4.1
5l1fC-1e4oA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbw ENDO-1,4-BETA-GLUCAN
ASE F


([Clostridium]
cellulolyticum)
PF02011
(Glyco_hydro_48)
4 ASP A 134
PRO A 135
TYR A 289
SER A 297
None
1.24A 5l1fC-1fbwA:
undetectable
5l1fC-1fbwA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fob BETA-1,4-GALACTANASE

(Aspergillus
aculeatus)
PF07745
(Glyco_hydro_53)
4 ASP A 181
TYR A 215
SER A 132
ASN A 135
None
1.22A 5l1fC-1fobA:
2.3
5l1fC-1fobA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h14 ENDO-1,4-BETA-XYLANA
SE


(Pseudoalteromonas
haloplanktis)
PF01270
(Glyco_hydro_8)
4 PRO A 141
PHE A 191
SER A 202
ASN A 144
None
1.20A 5l1fC-1h14A:
undetectable
5l1fC-1h14A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hjv CHITINASE-3 LIKE
PROTEIN 1


(Homo sapiens)
PF00704
(Glyco_hydro_18)
4 PRO A 142
TYR A 189
PHE A 106
SER A  95
None
1.23A 5l1fC-1hjvA:
undetectable
5l1fC-1hjvA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II


(Salmonella
enterica)
PF00117
(GATase)
PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N)
4 SER B  11
ASP B  10
PRO B  57
SER A 427
None
1.16A 5l1fC-1i1qB:
3.5
5l1fC-1i1qB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8g TELOMERE-BINDING
PROTEIN ALPHA
SUBUNIT


(Sterkiella nova)
PF02765
(POT1)
4 SER A 249
ASP A 247
PHE A 253
ASN A 215
None
1.24A 5l1fC-1k8gA:
undetectable
5l1fC-1k8gA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5x SURVIVAL PROTEIN E

(Pyrobaculum
aerophilum)
PF01975
(SurE)
4 SER A 106
TYR A 192
SER A 169
ASN A  97
None
1.22A 5l1fC-1l5xA:
3.9
5l1fC-1l5xA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ljy MGP-40

(Capra hircus)
PF00704
(Glyco_hydro_18)
4 PRO A 121
TYR A 168
PHE A  85
SER A  74
None
1.14A 5l1fC-1ljyA:
2.3
5l1fC-1ljyA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mek PROTEIN DISULFIDE
ISOMERASE


(Homo sapiens)
PF00085
(Thioredoxin)
4 ASP A  92
PRO A  96
TYR A  77
PHE A  87
None
1.24A 5l1fC-1mekA:
undetectable
5l1fC-1mekA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 37 KDA
SUBUNIT
ACTIVATOR 1 95 KDA
SUBUNIT


(Saccharomyces
cerevisiae)
PF00004
(AAA)
PF08519
(RFC1)
PF08542
(Rep_fac_C)
4 PRO A 589
TYR A 581
PHE A 587
SER B 147
None
1.21A 5l1fC-1sxjA:
undetectable
5l1fC-1sxjA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ule GALECTIN-2

(Coprinopsis
cinerea)
PF00337
(Gal-bind_lectin)
4 SER A 130
TYR A  80
PHE A  39
SER A  27
None
1.18A 5l1fC-1uleA:
undetectable
5l1fC-1uleA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3x IRON-RESPONSIVE
ELEMENT BINDING
PROTEIN 1


(Homo sapiens)
PF00330
(Aconitase)
PF00694
(Aconitase_C)
4 PRO A 514
TYR A 417
SER A 138
ASN A 133
EDO  A1002 ( 4.7A)
None
None
EDO  A1002 (-3.1A)
1.11A 5l1fC-2b3xA:
undetectable
5l1fC-2b3xA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1l RESTRICTION
ENDONUCLEASE


(Bacillus firmus)
PF13091
(PLDc_2)
4 ASP A 142
PHE A   3
SER A  29
ASN A  30
None
1.08A 5l1fC-2c1lA:
undetectable
5l1fC-2c1lA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1g ACID PHOSPHATASE

(Francisella
tularensis)
PF04185
(Phosphoesterase)
4 PRO A 259
TYR A 262
SER A 298
ASN A 299
None
1.24A 5l1fC-2d1gA:
undetectable
5l1fC-2d1gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3r LECTIN ALPHA CHAIN

(Cratylia
argentea)
PF00139
(Lectin_legB)
4 SER A 218
ASP A   2
PHE A 232
SER A  94
None
1.17A 5l1fC-2d3rA:
undetectable
5l1fC-2d3rA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7t BASIC AGGLUTININ

(Psophocarpus
tetragonolobus)
PF00139
(Lectin_legB)
4 SER A 214
ASP A 212
TYR A 106
PHE A 126
GAL  A 401 ( 3.1A)
A2G  A 400 (-4.9A)
A2G  A 400 ( 4.7A)
A2G  A 400 ( 3.8A)
1.24A 5l1fC-2e7tA:
undetectable
5l1fC-2e7tA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsn PHOSPHODIESTERASE-NU
CLEOTIDE
PYROPHOSPHATASE


(Xanthomonas
citri)
PF01663
(Phosphodiest)
4 SER A 371
PRO A 218
TYR A 223
SER A  88
None
1.17A 5l1fC-2gsnA:
undetectable
5l1fC-2gsnA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i58 SUGAR ABC
TRANSPORTER,
SUGAR-BINDING
PROTEIN


(Streptococcus
pneumoniae)
PF13416
(SBP_bac_8)
4 PRO A  66
TYR A 100
SER A 245
ASN A 114
None
1.14A 5l1fC-2i58A:
undetectable
5l1fC-2i58A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i58 SUGAR ABC
TRANSPORTER,
SUGAR-BINDING
PROTEIN


(Streptococcus
pneumoniae)
PF13416
(SBP_bac_8)
4 PRO A  66
TYR A 100
SER A 317
ASN A 114
None
0.64A 5l1fC-2i58A:
undetectable
5l1fC-2i58A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i58 SUGAR ABC
TRANSPORTER,
SUGAR-BINDING
PROTEIN


(Streptococcus
pneumoniae)
PF13416
(SBP_bac_8)
4 PRO A 110
TYR A  96
SER A 245
ASN A 114
None
1.12A 5l1fC-2i58A:
undetectable
5l1fC-2i58A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
ALPHA-SUBUNIT


(Aromatoleum
aromaticum)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
4 SER A 263
TYR A 443
PHE A 267
ASN A 668
SF4  A1984 ( 4.4A)
None
None
None
1.18A 5l1fC-2ivfA:
undetectable
5l1fC-2ivfA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4l URIDYLATE KINASE

(Sulfolobus
solfataricus)
PF00696
(AA_kinase)
4 PRO A 149
TYR A 145
SER A   8
ASN A 140
None
None
UTP  A1227 (-3.6A)
None
1.12A 5l1fC-2j4lA:
3.0
5l1fC-2j4lA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kpy MAJOR POLLEN
ALLERGEN ART V 1


(Artemisia
vulgaris)
PF00304
(Gamma-thionin)
4 ASP A  23
TYR A  13
SER A  78
ASN A  19
None
1.22A 5l1fC-2kpyA:
undetectable
5l1fC-2kpyA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE


(Synechococcus
elongatus)
PF00427
(PBS_linker_poly)
4 PRO A 131
TYR A 121
PHE A  54
SER A  61
None
1.25A 5l1fC-2l3wA:
undetectable
5l1fC-2l3wA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE


(Aquifex
aeolicus)
PF00793
(DAHP_synth_1)
4 SER A1043
ASP A1081
PRO A1101
SER A1232
PEP  A1268 (-3.6A)
PEP  A1268 ( 4.5A)
PEP  A1268 (-4.0A)
None
1.20A 5l1fC-2nxgA:
undetectable
5l1fC-2nxgA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nya PERIPLASMIC NITRATE
REDUCTASE


(Escherichia
coli)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
4 ASP A 171
PHE A 173
SER A 197
ASN A 198
None
1.01A 5l1fC-2nyaA:
undetectable
5l1fC-2nyaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE


(Escherichia
virus N4)
no annotation 4 PRO A1066
PHE A 591
SER A 604
ASN A 600
None
1.21A 5l1fC-2po4A:
undetectable
5l1fC-2po4A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qri H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN K-B ALPHA
CHAIN, BETA-2
MICROGLOBULIN,
OVALBUMIN-DERIVED
PEPTIDE


(Mus musculus)
PF00129
(MHC_I)
PF07654
(C1-set)
4 ASP A 212
PRO A 210
TYR A 209
SER A   4
None
1.21A 5l1fC-2qriA:
undetectable
5l1fC-2qriA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0s CHROMATIN
STRUCTURE-REMODELING
COMPLEX PROTEIN RSC4


(Saccharomyces
cerevisiae)
PF00439
(Bromodomain)
4 PRO A  84
PHE A  80
SER A 138
ASN A 134
None
1.11A 5l1fC-2r0sA:
2.8
5l1fC-2r0sA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0v CHROMATIN
STRUCTURE-REMODELING
COMPLEX PROTEIN RSC4


(Saccharomyces
cerevisiae)
PF00439
(Bromodomain)
4 PRO A  84
PHE A  80
SER A 138
ASN A 134
ALY  A  25 ( 4.2A)
None
None
ALY  A  25 ( 3.3A)
1.06A 5l1fC-2r0vA:
undetectable
5l1fC-2r0vA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uut RNA-DIRECTED RNA
POLYMERASE


(Sapporo virus)
PF00680
(RdRP_1)
4 ASP A 188
PRO A 120
TYR A 286
SER A 281
None
1.10A 5l1fC-2uutA:
undetectable
5l1fC-2uutA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgy CYTOCHROME P450 130

(Mycobacterium
tuberculosis)
PF00067
(p450)
4 SER A  67
ASP A  93
PRO A  94
SER A 348
HEM  A 450 ( 4.8A)
None
None
HEM  A 450 (-3.4A)
1.17A 5l1fC-2wgyA:
undetectable
5l1fC-2wgyA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzf GLUCOSYLTRANSFERASE

(Legionella
pneumophila)
PF16849
(Glyco_transf_88)
4 SER A 519
PRO A 522
TYR A 440
SER A 229
UDP  A1525 (-2.8A)
None
None
UDP  A1525 (-2.8A)
1.22A 5l1fC-2wzfA:
2.2
5l1fC-2wzfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn0 TRANSCRIPTION FACTOR
TAU 55 KDA SUBUNIT


(Saccharomyces
cerevisiae)
PF00300
(His_Phos_1)
4 ASP A  31
PRO A 103
TYR A  94
SER A  15
None
1.20A 5l1fC-2yn0A:
3.1
5l1fC-2yn0A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoa PHOSPHOHYDROLASE

(Klebsiella
aerogenes)
PF00149
(Metallophos)
4 ASP A 168
PRO A 169
SER A 198
ASN A 196
None
1.16A 5l1fC-2zoaA:
2.3
5l1fC-2zoaA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asp CAPSID PROTEIN

(Norwalk virus)
PF00915
(Calici_coat)
PF08435
(Calici_coat_C)
4 PRO A 404
TYR A 406
PHE A 326
SER A 245
None
1.13A 5l1fC-3aspA:
undetectable
5l1fC-3aspA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdi UNCHARACTERIZED
PROTEIN TA0194


(Thermoplasma
acidophilum)
PF00561
(Abhydrolase_1)
PF12146
(Hydrolase_4)
4 SER A  39
ASP A  62
TYR A  92
PHE A   7
None
1.16A 5l1fC-3bdiA:
3.3
5l1fC-3bdiA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhc ATP-DEPENDENT RNA
HELICASE DDX19B
NUCLEAR PORE COMPLEX
PROTEIN NUP214


(Homo sapiens)
PF00270
(DEAD)
PF12894
(ANAPC4_WD40)
4 SER B 280
ASP A  76
PRO A  77
SER B 274
None
1.14A 5l1fC-3fhcB:
undetectable
5l1fC-3fhcB:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9f PUTATIVE TYPE 11
METHYLTRANSFERASE


(Sulfolobus
solfataricus)
PF08241
(Methyltransf_11)
4 PRO A 162
TYR A  23
PHE A 167
ASN A  97
None
0.96A 5l1fC-3i9fA:
2.9
5l1fC-3i9fA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-PROCESSING
FACTOR 19


(Schizosaccharomyces
pombe)
PF08606
(Prp19)
4 SER S   4
PRO S  10
SER S  19
ASN S  21
None
1.14A 5l1fC-3jb9S:
undetectable
5l1fC-3jb9S:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgx PUTATIVE P450
MONOOXYGENASE


(Amycolatopsis
balhimycina)
PF00067
(p450)
4 ASP A 316
PRO A 317
PHE A 320
SER A 280
None
1.10A 5l1fC-3mgxA:
undetectable
5l1fC-3mgxA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzq BIOSYNTHETIC
ARGININE
DECARBOXYLASE


(Escherichia
coli)
PF02784
(Orn_Arg_deC_N)
4 ASP A  64
PRO A  63
TYR A  48
SER A 141
None
1.02A 5l1fC-3nzqA:
undetectable
5l1fC-3nzqA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o82 PEPTIDE ARYLATION
ENZYME


(Acinetobacter
baumannii)
PF00501
(AMP-binding)
4 SER A 366
ASP A 367
PRO A 393
TYR A 394
None
1.23A 5l1fC-3o82A:
4.2
5l1fC-3o82A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ofl L1

(Alphapapillomavirus
7)
PF00500
(Late_protein_L1)
4 SER A 398
PRO A 441
TYR A 442
ASN A 396
None
1.02A 5l1fC-3oflA:
undetectable
5l1fC-3oflA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3on6 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF06824
(Glyco_hydro_125)
4 SER A 265
PRO A 395
PHE A 333
SER A 260
None
1.23A 5l1fC-3on6A:
undetectable
5l1fC-3on6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2c PUTATIVE GLYCOSYL
HYDROLASE


(Bacteroides
ovatus)
PF06824
(Glyco_hydro_125)
4 SER A 271
PRO A 401
PHE A 339
SER A 266
None
1.24A 5l1fC-3p2cA:
undetectable
5l1fC-3p2cA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppx VON WILLEBRAND
FACTOR


(Homo sapiens)
PF00092
(VWA)
4 PRO A1632
PHE A1654
SER A1506
ASN A1610
None
1.16A 5l1fC-3ppxA:
5.8
5l1fC-3ppxA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ptk BETA-GLUCOSIDASE
OS4BGLU12


(Oryza sativa)
PF00232
(Glyco_hydro_1)
4 SER A 363
ASP A 397
SER A 451
ASN A 452
None
1.15A 5l1fC-3ptkA:
undetectable
5l1fC-3ptkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pyw S-LAYER PROTEIN SAP

(Bacillus
anthracis)
PF00395
(SLH)
4 ASP A   7
PRO A   6
PHE A   5
ASN A  30
None
1.14A 5l1fC-3pywA:
undetectable
5l1fC-3pywA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qt3 PUTATIVE
UNCHARACTERIZED
PROTEIN CPE0426


(Clostridium
perfringens)
PF06824
(Glyco_hydro_125)
4 SER A 308
PRO A 230
PHE A 234
SER A  68
None
1.24A 5l1fC-3qt3A:
undetectable
5l1fC-3qt3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT L
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N


(Escherichia
coli)
no annotation 4 ASP N 229
PRO N 228
TYR N 300
SER L 597
None
1.20A 5l1fC-3rkoN:
2.7
5l1fC-3rkoN:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5t PUTATIVE
GLYCOSYLTRANSFERASE


(Streptomyces
hygroscopicus)
PF00982
(Glyco_transf_20)
4 SER A 388
PRO A 393
SER A 380
ASN A 386
None
1.18A 5l1fC-3t5tA:
undetectable
5l1fC-3t5tA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr5 V-TYPE SODIUM ATPASE
CATALYTIC SUBUNIT A
V-TYPE SODIUM ATPASE
SUBUNIT B


(Enterococcus
hirae)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn)
4 PRO D 225
TYR D 253
SER A  56
ASN D 112
None
1.17A 5l1fC-3vr5D:
undetectable
5l1fC-3vr5D:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0w T36-5 TCR BETA CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 ASP E  38
PRO E  39
SER E  82
ASN E  84
None
1.18A 5l1fC-3w0wE:
undetectable
5l1fC-3w0wE:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1g DNA LIGASE 4

(Homo sapiens)
PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C)
4 ASP A 441
PRO A 440
TYR A 438
SER A 292
None
None
None
SO4  A 703 (-2.3A)
1.26A 5l1fC-3w1gA:
undetectable
5l1fC-3w1gA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zg8 PENICILLIN-BINDING
PROTEIN 4


(Listeria
monocytogenes)
PF00905
(Transpeptidase)
PF00912
(Transgly)
4 SER B 394
PRO B 398
TYR B 504
SER B 623
AIX  B 800 (-0.2A)
None
None
AIX  B 800 (-2.4A)
1.20A 5l1fC-3zg8B:
undetectable
5l1fC-3zg8B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 PRO A1156
TYR A1141
SER A1188
ASN A1254
None
1.11A 5l1fC-3zyvA:
undetectable
5l1fC-3zyvA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4acz ENDO-ALPHA-MANNOSIDA
SE


(Bacteroides
thetaiotaomicron)
PF16317
(Glyco_hydro_99)
4 ASP B 129
TYR B 175
SER B  99
ASN B  48
None
1.22A 5l1fC-4aczB:
undetectable
5l1fC-4aczB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag9 GLUCOSAMINE-6-PHOSPH
ATE
N-ACETYLTRANSFERASE


(Caenorhabditis
elegans)
PF00583
(Acetyltransf_1)
4 ASP A  20
PRO A  19
SER A  78
ASN A  77
None
1.13A 5l1fC-4ag9A:
undetectable
5l1fC-4ag9A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ay1 CHITINASE-3-LIKE
PROTEIN 2


(Homo sapiens)
PF00704
(Glyco_hydro_18)
4 PRO A 147
TYR A 195
PHE A 111
SER A 100
None
1.13A 5l1fC-4ay1A:
3.3
5l1fC-4ay1A:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzi SEC23P

(Saccharomyces
cerevisiae)
PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS)
4 PRO A 709
PHE A 660
SER A 621
ASN A 620
None
1.19A 5l1fC-4bziA:
4.2
5l1fC-4bziA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4el8 GLYCOSIDE HYDROLASE
FAMILY 48


(Caldicellulosiruptor
bescii)
PF02011
(Glyco_hydro_48)
4 ASP A 131
PRO A 132
TYR A 290
SER A 298
None
1.24A 5l1fC-4el8A:
undetectable
5l1fC-4el8A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgm AMINOPEPTIDASE N
FAMILY PROTEIN


(Idiomarina
loihiensis)
PF05299
(Peptidase_M61)
PF13180
(PDZ_2)
4 SER A  93
ASP A  91
PHE A  46
SER A  40
None
None
None
MAE  A 601 ( 3.7A)
1.21A 5l1fC-4fgmA:
undetectable
5l1fC-4fgmA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fus RTX TOXINS AND
RELATED CA2+-BINDING
PROTEIN


(Hahella
chejuensis)
PF02011
(Glyco_hydro_48)
4 ASP A 160
PRO A 161
TYR A 321
SER A 329
None
EDO  A 819 ( 4.7A)
None
OHI  A 352 ( 4.4A)
1.22A 5l1fC-4fusA:
undetectable
5l1fC-4fusA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1i PROTEIN PRGH

(Salmonella
enterica)
PF09480
(PrgH)
4 PRO A 256
TYR A 285
SER A 233
ASN A 229
None
1.07A 5l1fC-4g1iA:
undetectable
5l1fC-4g1iA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6q PROLINE
DEHYDROGENASE


(Deinococcus
radiodurans)
PF01619
(Pro_dh)
4 SER A  96
ASP A 135
TYR A 288
ASN A  58
None
TFB  A2002 ( 3.7A)
TFB  A2002 (-4.7A)
None
1.16A 5l1fC-4h6qA:
undetectable
5l1fC-4h6qA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irx SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN


(Caulobacter
vibrioides)
PF13407
(Peripla_BP_4)
4 SER A 174
PHE A  52
SER A 203
ASN A 168
INS  A 401 (-2.5A)
None
INS  A 401 (-2.7A)
INS  A 401 (-3.8A)
1.17A 5l1fC-4irxA:
15.3
5l1fC-4irxA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum)
PF00995
(Sec1)
4 ASP A 510
PRO A 511
TYR A 516
SER A 322
None
1.24A 5l1fC-4jc8A:
3.0
5l1fC-4jc8A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnm CHITINASE A

(Cycas revoluta)
PF00704
(Glyco_hydro_18)
4 PRO A 121
TYR A 174
PHE A  85
SER A  73
None
1.25A 5l1fC-4mnmA:
3.4
5l1fC-4mnmA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqr CYP105AS1

(Amycolatopsis
orientalis)
PF00067
(p450)
4 ASP A 318
PRO A 319
PHE A 322
SER A 280
None
1.16A 5l1fC-4oqrA:
undetectable
5l1fC-4oqrA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqs CYP105AS1

(Amycolatopsis
orientalis)
PF00067
(p450)
4 ASP A 318
PRO A 319
PHE A 322
SER A 280
None
1.17A 5l1fC-4oqsA:
undetectable
5l1fC-4oqsA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4owx SOSS COMPLEX SUBUNIT
B1


(Homo sapiens)
PF01336
(tRNA_anti-codon)
4 SER B 109
PRO B 111
SER B  53
ASN B  51
None
1.23A 5l1fC-4owxB:
undetectable
5l1fC-4owxB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy2 TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 1
TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 7


(Saccharomyces
cerevisiae)
PF04658
(TAFII55_N)
PF12157
(DUF3591)
4 TYR B 238
PHE A 498
SER A 639
ASN A 645
None
1.22A 5l1fC-4oy2B:
undetectable
5l1fC-4oy2B:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r33 NOSL

(Streptomyces
actuosus)
PF06968
(BATS)
4 SER A 362
ASP A 345
PRO A 348
TYR A 349
None
1.17A 5l1fC-4r33A:
2.5
5l1fC-4r33A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7q SENSOR HISTIDINE
KINASE


(Vibrio cholerae)
PF11884
(DUF3404)
4 SER A 135
PRO A 114
TYR A  86
PHE A 117
None
1.20A 5l1fC-4r7qA:
undetectable
5l1fC-4r7qA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgg PUTATIVE PHAGE
STRUCTURAL PROTEIN


(Lactococcus
phage 1358)
no annotation 4 SER A 202
ASP A 243
PRO A 242
PHE A 240
None
None
None
GN1  A 401 ( 4.3A)
1.26A 5l1fC-4rggA:
undetectable
5l1fC-4rggA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rpf HOMOSERINE KINASE

(Yersinia pestis)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
4 SER A  94
PRO A 178
TYR A 287
PHE A 294
CIT  A 401 (-3.6A)
None
None
None
1.24A 5l1fC-4rpfA:
undetectable
5l1fC-4rpfA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnm IMPORTIN SUBUNIT
ALPHA


(Arabidopsis
thaliana)
PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3)
4 SER A 160
PRO A 164
TYR A 202
PHE A 166
None
1.26A 5l1fC-4tnmA:
2.6
5l1fC-4tnmA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4we6 HEMAGGLUTININ HA1
CHAIN


(Influenza A
virus)
PF00509
(Hemagglutinin)
4 SER A  55
ASP A  33
PRO A  34
PHE A 108
None
1.25A 5l1fC-4we6A:
undetectable
5l1fC-4we6A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zke SUPERKILLER PROTEIN
7


(Saccharomyces
cerevisiae)
PF00009
(GTP_EFTU)
4 ASP A 376
PRO A 377
TYR A 380
ASN A 728
ASP  A 376 ( 0.6A)
PRO  A 377 ( 1.1A)
TYR  A 380 ( 1.3A)
ASN  A 728 ( 0.6A)
1.02A 5l1fC-4zkeA:
4.6
5l1fC-4zkeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3h PROTEIN SCARECROW
PROTEIN SHORT-ROOT


(Arabidopsis
thaliana)
PF03514
(GRAS)
4 SER A 317
PRO A 322
TYR A 323
SER B 185
None
1.24A 5l1fC-5b3hA:
3.9
5l1fC-5b3hA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5doo PROTEIN LYSINE
METHYLTRANSFERASE 2


(Rickettsia
typhi)
PF10119
(MethyTransf_Reg)
PF13847
(Methyltransf_31)
4 SER A 253
ASP A 251
PHE A 147
SER A  21
None
1.26A 5l1fC-5dooA:
undetectable
5l1fC-5dooA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hk8 PROBABLE
PHEOPHORBIDASE


(Arabidopsis
thaliana)
PF12697
(Abhydrolase_6)
4 SER A 166
PRO A 246
PHE A 242
SER A 174
None
0.75A 5l1fC-5hk8A:
3.5
5l1fC-5hk8A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6z SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER


(Homo sapiens)
PF00209
(SNF)
4 SER A 336
TYR A 176
SER A 375
ASN A 101
None
1.25A 5l1fC-5i6zA:
undetectable
5l1fC-5i6zA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iry DESMOCOLLIN-1

(Homo sapiens)
PF00028
(Cadherin)
4 SER A 254
ASP A 245
PRO A 218
ASN A 278
None
CA  A 607 (-2.1A)
None
None
1.21A 5l1fC-5iryA:
undetectable
5l1fC-5iryA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kjo ENDOGLUCANASE V-LIKE
PROTEIN


(Phanerochaete
chrysosporium)
no annotation 4 SER A  14
PRO A  66
TYR A  67
ASN A 105
None
1.21A 5l1fC-5kjoA:
undetectable
5l1fC-5kjoA:
13.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2


(Rattus
norvegicus)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)
4 ASP A 519
TYR A 616
SER A 788
ASN A 791
None
0.87A 5l1fC-5l1bA:
46.0
5l1fC-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2


(Rattus
norvegicus)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)
4 SER A 516
ASP A 519
TYR A 616
ASN A 791
None
1.00A 5l1fC-5l1bA:
46.0
5l1fC-5l1bA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5li8 PUTATIVE CYTOCHROME
P450 126


(Mycobacterium
tuberculosis)
PF00067
(p450)
4 ASP A 334
PRO A 335
PHE A 338
SER A 298
None
1.20A 5l1fC-5li8A:
undetectable
5l1fC-5li8A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lqd ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE


(Streptomyces
venezuelae)
PF00982
(Glyco_transf_20)
4 ASP A 262
TYR A 310
SER A 383
ASN A 357
None
1.15A 5l1fC-5lqdA:
4.3
5l1fC-5lqdA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgv PHENYLALANINE--TRNA
LIGASE,
MITOCHONDRIAL


(Homo sapiens)
PF01409
(tRNA-synt_2d)
PF03147
(FDX-ACB)
4 SER A 149
ASP A 292
PRO A 291
TYR A 289
None
1.24A 5l1fC-5mgvA:
undetectable
5l1fC-5mgvA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oj7 NAD-DEPENDENT
PROTEIN DEACYLASE


(Xenopus
tropicalis)
no annotation 4 SER A  65
PRO A  71
PHE A 115
ASN A 143
None
1.24A 5l1fC-5oj7A:
undetectable
5l1fC-5oj7A:
6.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN


(Mus musculus;
Rattus
norvegicus)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF07803
(GSG-1)
PF10613
(Lig_chan-Glu_bd)
4 SER A 516
ASP A 519
PRO A 520
TYR A 616
None
0.72A 5l1fC-5welA:
55.6
5l1fC-5welA:
78.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA


(Mus musculus;
Rattus
norvegicus)
PF00060
(Lig_chan)
PF00822
(PMP22_Claudin)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)
4 SER A 516
ASP A 519
PRO A 520
TYR A 616
None
0.79A 5l1fC-5weoA:
51.8
5l1fC-5weoA:
77.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xep CHITINASE-3-LIKE
PROTEIN 1


(Mus musculus)
no annotation 4 PRO A 143
TYR A 190
PHE A 107
SER A  96
None
1.03A 5l1fC-5xepA:
2.7
5l1fC-5xepA:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT


(Homo sapiens)
PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194)
4 SER C3432
ASP C3435
PHE C3382
ASN C3430
None
1.21A 5l1fC-5y3rC:
undetectable
5l1fC-5y3rC:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yj6 DOCKERIN TYPE I
REPEAT-CONTAINING
PROTEIN


(Ruminiclostridium
thermocellum)
no annotation 4 ASP A 165
PRO A 166
TYR A 317
ASN A 296
None
1.25A 5l1fC-5yj6A:
undetectable
5l1fC-5yj6A:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8fab IGG1-LAMBDA HIL FAB
(HEAVY CHAIN)
IGG1-LAMBDA HIL FAB
(LIGHT CHAIN)


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 ASP B  99
PRO B 100
TYR A  48
PHE B 108
None
1.24A 5l1fC-8fabB:
undetectable
5l1fC-8fabB:
15.05