SIMILAR PATTERNS OF AMINO ACIDS FOR 5KIR_B_RCXB601_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e8c UDP-N-ACETYLMURAMOYL
ALANYL-D-GLUTAMATE--
2,6-DIAMINOPIMELATE
LIGASE

(Escherichia
coli) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 LEU A 329
ARG A 288
ILE A 298
PHE A 289
 None
 1.16A 5kirB-1e8cA:
0.0		 5kirB-1e8cA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f4h BETA-GALACTOSIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 LEU A 152
ARG A  26
ILE A 141
PHE A 143
 None
 0.99A 5kirB-1f4hA:
0.0		 5kirB-1f4hA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ixk METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF01189
(Methyltr_RsmB-F)
PF17125
(Methyltr_RsmF_N) 		4 LEU A  63
ARG A  45
ILE A 100
PHE A  47
 None
 1.33A 5kirB-1ixkA:
0.0		 5kirB-1ixkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsd HAEMAGGLUTININ (HA1
CHAIN)

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 LEU A  60
ARG A 102
ILE A  61
PHE A 105
 None
 1.12A 5kirB-1jsdA:
undetectable		 5kirB-1jsdA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mk7 TALIN

(Gallus gallus) 		PF00373
(FERM_M)
PF02174
(IRS) 		4 LEU B 260
ARG B 277
ILE B 279
PHE B 280
 None
 1.06A 5kirB-1mk7B:
undetectable		 5kirB-1mk7B:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5z FOLYLPOLYGLUTAMATE
SYNTHASE/DIHYDROFOLA
TE SYNTHASE

(Thermotoga
maritima) 		PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 LEU A 253
ARG A 239
ILE A 261
PHE A 240
 None
 1.11A 5kirB-1o5zA:
0.0		 5kirB-1o5zA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p2z HEXON PROTEIN

(Human
mastadenovirus
C) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 LEU A 347
ARG A 561
ILE A 575
PHE A 340
 None
 0.91A 5kirB-1p2zA:
0.0		 5kirB-1p2zA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)

(Rhinovirus A) 		PF00073
(Rhv) 		4 LEU 1 127
ARG 1 181
ILE 1 171
PHE 1 182
 None
 1.35A 5kirB-1r1a1:
0.0		 5kirB-1r1a1:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4v HYPOTHETICAL PROTEIN
AQ_328

(Aquifex
aeolicus) 		PF09123
(DUF1931) 		4 LEU A  40
ARG A  37
ILE A  42
PHE A  36
 None
CAC  A 203 (-2.8A)
None
None
 1.15A 5kirB-1r4vA:
undetectable		 5kirB-1r4vA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tu7 GLUTATHIONE
S-TRANSFERASE 2

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 LEU A  50
ARG A  32
ILE A  33
PHE A   8
 GSH  A1001 (-4.5A)
None
None
GSH  A1001 (-4.8A)
 1.31A 5kirB-1tu7A:
0.0		 5kirB-1tu7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u27 CYTOHESIN 2

(Mus musculus) 		PF00169
(PH) 		4 LEU A 325
ARG A 355
ILE A 356
PHE A 323
 None
 1.17A 5kirB-1u27A:
undetectable		 5kirB-1u27A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uis RED FLUORESCENT
PROTEIN FP611

(Entacmaea
quadricolor) 		PF01353
(GFP) 		4 LEU A  58
ARG A  92
ILE A  57
PHE A 102
 None
NRQ  A  63 ( 3.1A)
None
None
 1.33A 5kirB-1uisA:
undetectable		 5kirB-1uisA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vky S-ADENOSYLMETHIONINE
:TRNA
RIBOSYLTRANSFERASE-I
SOMERASE

(Thermotoga
maritima) 		PF02547
(Queuosine_synth) 		4 LEU A  28
ARG A  44
ILE A  46
PHE A  43
 None
 1.02A 5kirB-1vkyA:
undetectable		 5kirB-1vkyA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y0y FRV OPERON PROTEIN
FRVX

(Pyrococcus
horikoshii) 		PF05343
(Peptidase_M42) 		4 LEU A  12
ARG A 184
ILE A 185
PHE A 181
 None
 1.16A 5kirB-1y0yA:
undetectable		 5kirB-1y0yA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yis ADENYLOSUCCINATE
LYASE

(Caenorhabditis
elegans) 		PF00206
(Lyase_1) 		4 LEU A 351
ARG A 137
ILE A 354
PHE A 355
 None
 1.17A 5kirB-1yisA:
undetectable		 5kirB-1yisA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a6v EMP46P

(Saccharomyces
cerevisiae) 		PF03388
(Lectin_leg-like) 		4 LEU A  92
ARG A 199
ILE A 200
PHE A 198
 None
 1.22A 5kirB-2a6vA:
undetectable		 5kirB-2a6vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d58 ALLOGRAFT
INFLAMMATORY FACTOR
1

(Homo sapiens) 		no annotation 4 LEU A  70
ARG A  72
ILE A  65
PHE A  57
 None
 1.24A 5kirB-2d58A:
undetectable		 5kirB-2d58A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfe RIBONUCLEASE HII

(Thermococcus
kodakarensis) 		PF01351
(RNase_HII) 		4 LEU A  68
ARG A  11
ILE A  73
PHE A  83
 None
 1.27A 5kirB-2dfeA:
undetectable		 5kirB-2dfeA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN

(Sulfurisphaera
tokodaii) 		PF05694
(SBP56) 		4 LEU A 244
ARG A 240
ILE A 230
PHE A 232
 None
 1.32A 5kirB-2eceA:
undetectable		 5kirB-2eceA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6c CHLOROPHENOL
REDUCTION GENE K

(Desulfitobacterium
dehalogenans) 		PF13545
(HTH_Crp_2) 		4 LEU A 112
ARG A 117
ILE A 115
PHE A 116
 None
 1.05A 5kirB-2h6cA:
undetectable		 5kirB-2h6cA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ihy ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Staphylococcus
aureus) 		PF00005
(ABC_tran) 		4 LEU A  45
ARG A  77
ILE A 165
PHE A  82
 None
 1.14A 5kirB-2ihyA:
undetectable		 5kirB-2ihyA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5r GLUTAMYL-TRNA
SYNTHETASE 1

(Thermotoga
maritima) 		PF00749
(tRNA-synt_1c) 		4 LEU A 434
ARG A 462
ILE A 463
PHE A 459
 None
 1.08A 5kirB-2o5rA:
undetectable		 5kirB-2o5rA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obe HEXON

(Human
mastadenovirus
E) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 LEU A 317
ARG A 526
ILE A 540
PHE A 310
 None
 0.89A 5kirB-2obeA:
undetectable		 5kirB-2obeA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 LEU A 591
ARG A 613
ILE A 517
PHE A 583
 None
 1.15A 5kirB-2olsA:
undetectable		 5kirB-2olsA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ovl PUTATIVE RACEMASE

(Streptomyces
coelicolor) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  33
ARG A  13
ILE A  14
PHE A  31
 None
 1.34A 5kirB-2ovlA:
0.4		 5kirB-2ovlA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qi9 VITAMIN B12 IMPORT
SYSTEM PERMEASE
PROTEIN BTUC

(Escherichia
coli) 		PF01032
(FecCD) 		4 LEU A 287
ARG A 295
ILE A 305
PHE A 183
 None
 0.91A 5kirB-2qi9A:
0.0		 5kirB-2qi9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qk2 LP04448P

(Drosophila
melanogaster) 		PF12348
(CLASP_N) 		4 LEU A 367
ARG A 382
ILE A 385
PHE A 419
 None
 1.24A 5kirB-2qk2A:
undetectable		 5kirB-2qk2A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9q 2'-DEOXYCYTIDINE
5'-TRIPHOSPHATE
DEAMINASE

(Agrobacterium
fabrum) 		PF06559
(DCD) 		4 LEU A  44
ARG A 168
ILE A 167
PHE A 169
 None
 1.29A 5kirB-2r9qA:
undetectable		 5kirB-2r9qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ymz GALECTIN 2

(Gallus gallus) 		PF00337
(Gal-bind_lectin) 		4 LEU A 117
ARG A   3
ILE A 119
PHE A   5
 None
 1.35A 5kirB-2ymzA:
undetectable		 5kirB-2ymzA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 LEU X 215
ARG X 218
ILE X 725
PHE X 689
 None
 1.32A 5kirB-2zkmX:
undetectable		 5kirB-2zkmX:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqo PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		no annotation 4 LEU A 113
ARG A 116
ILE A 206
PHE A 115
 None
 0.94A 5kirB-3aqoA:
undetectable		 5kirB-3aqoA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bje NUCLEOSIDE
PHOSPHORYLASE,
PUTATIVE

(Trypanosoma
brucei) 		PF01048
(PNP_UDP_1) 		4 LEU A  96
ARG A 137
ILE A 135
PHE A  40
 None
R1P  A 401 (-3.0A)
None
None
 1.34A 5kirB-3bjeA:
undetectable		 5kirB-3bjeA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6g CYTOCHROME P450 2R1

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 377
ARG A 109
ILE A 401
PHE A 380
 None
HEM  A 601 (-2.4A)
None
None
 1.31A 5kirB-3c6gA:
undetectable		 5kirB-3c6gA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5o SERUM AMYLOID
P-COMPONENT

(Homo sapiens) 		PF00354
(Pentaxin) 		4 LEU A 157
ARG A  38
ILE A 154
PHE A  37
 None
 1.18A 5kirB-3d5oA:
undetectable		 5kirB-3d5oA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dla GLUTAMINE-DEPENDENT
NAD(+) SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 LEU A 159
ARG A 305
ILE A 306
PHE A 161
 None
 1.32A 5kirB-3dlaA:
0.4		 5kirB-3dlaA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1

(Arabidopsis
thaliana;
Escherichia
coli) 		PF00400
(WD40)
PF01547
(SBP_bac_1) 		4 LEU A  76
ARG A  66
ILE A  60
PHE A  47
 None
EDO  A 401 ( 4.8A)
None
None
 1.34A 5kirB-3dm0A:
undetectable		 5kirB-3dm0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3p PROTEIN KINASE,
PUTATIVE GLYCOGEN
SYNTHASE KINASE

(Leishmania
major) 		PF00069
(Pkinase) 		4 LEU A 243
ARG A 241
ILE A 239
PHE A 227
 None
 0.88A 5kirB-3e3pA:
undetectable		 5kirB-3e3pA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g40 NA-K-CL
COTRANSPORTER

(Methanosarcina
acetivorans) 		no annotation 4 LEU A 661
ARG A 514
ILE A 516
PHE A 512
 None
 0.97A 5kirB-3g40A:
undetectable		 5kirB-3g40A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I)
PF01590
(GAF)
PF13185
(GAF_2) 		4 LEU A 738
ARG A 641
ILE A 737
PHE A 642
 None
 1.12A 5kirB-3ibjA:
undetectable		 5kirB-3ibjA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4k DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		4 LEU A 760
ARG A 792
ILE A 794
PHE A 795
 None
 1.17A 5kirB-3l4kA:
undetectable		 5kirB-3l4kA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg5 EPI-ISOZIZAENE
SYNTHASE

(Streptomyces
coelicolor) 		no annotation 4 LEU A 206
ARG A 160
ILE A 202
PHE A 161
 None
 1.02A 5kirB-3lg5A:
undetectable		 5kirB-3lg5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtl CELL DIVISION
PROTEIN KINASE 16

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 371
ARG A 376
ILE A 374
PHE A 375
 None
 1.17A 5kirB-3mtlA:
undetectable		 5kirB-3mtlA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4o INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN

(Homo sapiens) 		PF13927
(Ig_3) 		4 LEU B  79
ARG B  82
ILE B  72
PHE B  81
 None
 1.33A 5kirB-3o4oB:
undetectable		 5kirB-3o4oB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob4 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ARAH 2

(Arachis
duranensis;
Escherichia
coli) 		PF00234
(Tryp_alpha_amyl)
PF13416
(SBP_bac_8) 		4 LEU A  76
ARG A  66
ILE A  60
PHE A  47
 None
MLR  A 400 (-3.8A)
None
None
 1.27A 5kirB-3ob4A:
undetectable		 5kirB-3ob4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT

(Campylobacter
jejuni) 		PF00694
(Aconitase_C) 		4 LEU A  92
ARG A  47
ILE A  24
PHE A  43
 None
 1.31A 5kirB-3q3wA:
undetectable		 5kirB-3q3wA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tc9 HYPOTHETICAL
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF01833
(TIG) 		4 LEU A 181
ARG A 448
ILE A 450
PHE A 163
 None
PO4  A 481 (-2.9A)
None
None
 1.34A 5kirB-3tc9A:
undetectable		 5kirB-3tc9A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uws HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF03415
(Peptidase_C11) 		4 LEU B 317
ARG B 312
ILE B 314
PHE B 313
 None
 0.94A 5kirB-3uwsB:
undetectable		 5kirB-3uwsB:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zif HEXON PROTEIN

(Bovine
mastadenovirus
B) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 LEU A 303
ARG A 508
ILE A 522
PHE A 296
 None
 0.94A 5kirB-3zifA:
undetectable		 5kirB-3zifA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzi SEC23P

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 LEU A 193
ARG A 186
ILE A 268
PHE A 182
 None
 0.99A 5kirB-4bziA:
undetectable		 5kirB-4bziA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1o BETA-XYLOSIDASE

(Parageobacillus
thermoglucosidasius) 		PF03512
(Glyco_hydro_52) 		4 LEU A 543
ARG A 548
ILE A 546
PHE A 547
 None
 0.90A 5kirB-4c1oA:
undetectable		 5kirB-4c1oA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chj IMC SUB-COMPARTMENT
PROTEIN ISP3

(Toxoplasma
gondii) 		no annotation 4 LEU A 144
ARG A 119
ILE A  90
PHE A 118
 None
 1.33A 5kirB-4chjA:
1.3		 5kirB-4chjA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fo5 THIOREDOXIN-LIKE
PROTEIN

(Parabacteroides
distasonis) 		PF13905
(Thioredoxin_8) 		4 LEU A  60
ARG A  56
ILE A 143
PHE A  50
 None
None
None
CL  A 200 (-3.7A)
 1.31A 5kirB-4fo5A:
undetectable		 5kirB-4fo5A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxp ADENYLYL-SULFATE
KINASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF01583
(APS_kinase) 		4 LEU A 220
ARG A 225
ILE A 229
PHE A 232
 ADX  A 301 ( 4.7A)
None
ADX  A 301 (-4.8A)
ADX  A 301 (-4.1A)
 1.10A 5kirB-4fxpA:
undetectable		 5kirB-4fxpA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfh DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF02518
(HATPase_c)
PF16898
(TOPRIM_C) 		4 LEU A 760
ARG A 792
ILE A 794
PHE A 795
 None
 1.18A 5kirB-4gfhA:
undetectable		 5kirB-4gfhA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hj3 LOV PROTEIN

(Rhodobacter
sphaeroides) 		PF13426
(PAS_9) 		4 LEU A  22
ARG A  10
ILE A   9
PHE A  13
 None
 1.34A 5kirB-4hj3A:
undetectable		 5kirB-4hj3A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htl BETA-GLUCOSIDE
KINASE

(Listeria
monocytogenes) 		PF00480
(ROK) 		4 LEU A 254
ARG A 247
ILE A 251
PHE A 250
 None
 1.28A 5kirB-4htlA:
undetectable		 5kirB-4htlA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lsw D-2-HYDROXYACID
DEHYDROGENSASE
PROTEIN

(Ketogulonicigenium
vulgare) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 301
ARG A  47
ILE A   6
PHE A  24
 None
 1.35A 5kirB-4lswA:
0.0		 5kirB-4lswA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhp GLUTAMINYL CYCLASE,
PUTATIVE

(Ixodes
scapularis) 		PF04389
(Peptidase_M28) 		4 LEU A 153
ARG A  67
ILE A  81
PHE A 179
 None
 1.28A 5kirB-4mhpA:
undetectable		 5kirB-4mhpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oxi ENTEROBACTIN
SYNTHETASE COMPONENT
F-RELATED PROTEIN

(Vibrio cholerae) 		PF00501
(AMP-binding) 		4 LEU A 142
ARG A 148
ILE A 151
PHE A 171
 None
 1.12A 5kirB-4oxiA:
undetectable		 5kirB-4oxiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oya ADENYLATE CYCLASE
TYPE 10

(Homo sapiens) 		PF00211
(Guanylate_cyc) 		4 LEU A 166
ARG A  33
ILE A 314
PHE A 157
 1VE  A 501 (-3.9A)
None
None
None
 1.09A 5kirB-4oyaA:
undetectable		 5kirB-4oyaA:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2

(Mus musculus) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 LEU A 353
ARG A 514
ILE A 518
PHE A 519
 IBP  A 601 ( 4.7A)
None
None
None
 0.34A 5kirB-4ph9A:
63.0		 5kirB-4ph9A:
87.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqx UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		PF12667
(NigD_N)
PF17415
(NigD_C) 		4 LEU A 161
ARG A 190
ILE A 129
PHE A 189
 None
EDO  A 301 ( 4.1A)
None
None
 1.28A 5kirB-4pqxA:
undetectable		 5kirB-4pqxA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkj D-LACTATE
DEHYDROGENASE

(Sporolactobacillus
inulinus) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A  34
ARG A  76
ILE A  48
PHE A   6
 None
 1.27A 5kirB-4xkjA:
0.0		 5kirB-4xkjA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xnu INTEGRAL MEMBRANE
PROTEIN-DOPAMINE
TRANSPORTER

(Drosophila
melanogaster) 		PF00209
(SNF) 		4 LEU A 433
ARG A 444
ILE A 440
PHE A 447
 None
 0.88A 5kirB-4xnuA:
0.0		 5kirB-4xnuA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z42 UREASE SUBUNIT ALPHA

(Yersinia
enterocolitica) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 LEU C 234
ARG C 271
ILE C 273
PHE C 268
 None
 1.20A 5kirB-4z42C:
undetectable		 5kirB-4z42C:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxs VIRION EGRESS
PROTEIN UL34

(Human
alphaherpesvirus
1) 		PF04541
(Herpes_U34) 		4 LEU A 164
ARG A 167
ILE A 153
PHE A 166
 None
 1.23A 5kirB-4zxsA:
undetectable		 5kirB-4zxsA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a3f DYNAMIN 3

(Homo sapiens) 		PF00169
(PH)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		4 LEU A 435
ARG A 343
ILE A 344
PHE A 340
 None
 1.34A 5kirB-5a3fA:
undetectable		 5kirB-5a3fA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3v BILIVERDIN REDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 4 LEU B 257
ARG B 265
ILE B 275
PHE B 259
 None
 1.25A 5kirB-5b3vB:
undetectable		 5kirB-5b3vB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5but KTR SYSTEM POTASSIUM
UPTAKE PROTEIN B

(Bacillus
subtilis) 		PF02386
(TrkH) 		4 LEU I 230
ARG I 341
ILE I 338
PHE I 339
 None
 1.29A 5kirB-5butI:
undetectable		 5kirB-5butI:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7r FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND TYPE-3
ICE-STRUCTURING
PROTEIN HPLC 12

(Escherichia
coli;
Zoarces
americanus) 		PF01547
(SBP_bac_1) 		4 LEU A  76
ARG A  66
ILE A  60
PHE A  47
 None
MLR  A 501 (-3.5A)
None
None
 1.30A 5kirB-5c7rA:
undetectable		 5kirB-5c7rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cgl ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE NMFIC

(Neisseria
meningitidis) 		PF02661
(Fic) 		4 LEU A  25
ARG A 172
ILE A  31
PHE A  26
 None
 1.23A 5kirB-5cglA:
undetectable		 5kirB-5cglA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cl2 SPORULATION-CONTROL
PROTEIN SPO0M

(Bacillus
subtilis) 		PF07070
(Spo0M) 		4 LEU A 191
ARG A 153
ILE A 147
PHE A 152
 None
 1.00A 5kirB-5cl2A:
undetectable		 5kirB-5cl2A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d2e MLNE

(Bacillus
velezensis) 		PF08659
(KR) 		4 LEU A 391
ARG A 440
ILE A 357
PHE A 403
 None
 1.31A 5kirB-5d2eA:
undetectable		 5kirB-5d2eA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f0o COHESIN SUBUNIT
PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P

(Lachancea
thermotolerans) 		no annotation 4 LEU A 605
ARG A 645
ILE A 649
PHE A 644
 None
 1.25A 5kirB-5f0oA:
0.4		 5kirB-5f0oA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g47 SFTSV GC

(SFTS
phlebovirus) 		PF07245
(Phlebovirus_G2) 		4 LEU A 790
ARG A 865
ILE A 861
PHE A 866
 None
 1.16A 5kirB-5g47A:
undetectable		 5kirB-5g47A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs6 NS1 OF ZIKA VIRUS
FROM 2015 BRAZIL
STRAIN

(Zika virus) 		PF00948
(Flavi_NS1) 		4 LEU A 321
ARG A 324
ILE A 275
PHE A 323
 None
 1.14A 5kirB-5gs6A:
undetectable		 5kirB-5gs6A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gui CHAPERONE PROTEIN
CLPC1, CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF02861
(Clp_N) 		4 LEU A 181
ARG A  97
ILE A 196
PHE A  98
 None
 1.22A 5kirB-5guiA:
undetectable		 5kirB-5guiA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gv0 LYSOSOME-ASSOCIATED
MEMBRANE
GLYCOPROTEIN 1

(Mus musculus) 		PF01299
(Lamp) 		4 LEU A 299
ARG A 273
ILE A 233
PHE A 247
 None
 1.36A 5kirB-5gv0A:
undetectable		 5kirB-5gv0A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)

(Naja atra) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		4 LEU A 154
ARG A 150
ILE A 474
PHE A 149
 None
 1.15A 5kirB-5gz4A:
undetectable		 5kirB-5gz4A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		4 LEU A 955
ARG A 960
ILE A 958
PHE A 959
 None
 1.15A 5kirB-5h64A:
undetectable		 5kirB-5h64A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h82 HETEROYOHIMBINE
SYNTHASE THAS2

(Catharanthus
roseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 275
ARG A 307
ILE A 262
PHE A 285
 None
 1.22A 5kirB-5h82A:
undetectable		 5kirB-5h82A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hop LMO0182 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 LEU A 196
ARG A 235
ILE A 230
PHE A 234
 None
 1.28A 5kirB-5hopA:
undetectable		 5kirB-5hopA:
18.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2

(Homo sapiens) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 LEU A 352
ARG A 513
ILE A 517
PHE A 518
 ID8  A 601 (-4.1A)
None
None
None
 0.68A 5kirB-5ikrA:
63.8		 5kirB-5ikrA:
99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy3 GENOME POLYPROTEIN

(Zika virus) 		PF00948
(Flavi_NS1) 		4 LEU A 321
ARG A 324
ILE A 275
PHE A 323
 None
 1.02A 5kirB-5iy3A:
undetectable		 5kirB-5iy3A:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j92 PUTATIVE ALPHA KG
DEPENDENT 2,4-D
DIOXYGENASE

(Paraburkholderia
xenovorans) 		PF02668
(TauD) 		4 LEU A  43
ARG A  15
ILE A  16
PHE A  45
 None
 1.25A 5kirB-5j92A:
undetectable		 5kirB-5j92A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ja9 TOXIN HIGB-2

(Vibrio cholerae) 		PF06296
(RelE) 		4 LEU C  78
ARG C  15
ILE C  65
PHE C  27
 None
 1.21A 5kirB-5ja9C:
undetectable		 5kirB-5ja9C:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jze RNA-DEPENDENT RNA
POLYMERASE

(Thiafora
orthonairovirus) 		PF02338
(OTU) 		4 LEU A   7
ARG A 161
ILE A 160
PHE A  32
 None
 1.28A 5kirB-5jzeA:
undetectable		 5kirB-5jzeA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldn HEXON PROTEIN,HEXON
CAPSID

(Human
mastadenovirus
C) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 LEU A 335
ARG A 545
ILE A 559
PHE A 328
 None
 0.92A 5kirB-5ldnA:
undetectable		 5kirB-5ldnA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndx GLYCOSYL HYDROLASE

(Rhizobium
leguminosarum) 		no annotation 4 LEU A 310
ARG A  23
ILE A 292
PHE A  21
 None
8U8  A 713 ( 3.7A)
None
None
 1.35A 5kirB-5ndxA:
undetectable		 5kirB-5ndxA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 LEU A2723
ARG A2684
ILE A2680
PHE A2727
 None
ATP  A4802 (-3.7A)
None
None
 1.18A 5kirB-5nugA:
undetectable		 5kirB-5nugA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5

(Homo sapiens) 		PF01663
(Phosphodiest) 		4 LEU A  43
ARG A  39
ILE A 351
PHE A  38
 None
 0.89A 5kirB-5vemA:
undetectable		 5kirB-5vemA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5veo ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5

(Mus musculus) 		PF01663
(Phosphodiest) 		4 LEU A  43
ARG A  39
ILE A 351
PHE A  38
 None
 0.93A 5kirB-5veoA:
undetectable		 5kirB-5veoA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpz FERMITIN FAMILY
HOMOLOG 2

(Mus musculus) 		PF00373
(FERM_M) 		4 LEU A 593
ARG A 595
ILE A 586
PHE A 636
 None
 1.34A 5kirB-5xpzA:
undetectable		 5kirB-5xpzA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvm STEROL
3-BETA-GLUCOSYLTRANS
FERASE

(Saccharomyces
cerevisiae) 		PF00201
(UDPGT)
PF03033
(Glyco_transf_28) 		4 LEU A1159
ARG A 958
ILE A1155
PHE A 865
 None
 1.23A 5kirB-5xvmA:
undetectable		 5kirB-5xvmA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yow GLYCOPROTEIN
POLYPROTEIN

(Heartland virus) 		no annotation 4 LEU A 228
ARG A 303
ILE A 299
PHE A 304
 None
 1.18A 5kirB-5yowA:
undetectable		 5kirB-5yowA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c01 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 3

(Homo sapiens) 		no annotation 4 LEU A 174
ARG A 170
ILE A 495
PHE A 169
 None
 1.26A 5kirB-6c01A:
undetectable		 5kirB-6c01A:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA

(Salmonella
enterica) 		no annotation 4 LEU A 503
ARG A 391
ILE A 496
PHE A 394
 None
 1.36A 5kirB-6ch3A:
undetectable		 5kirB-6ch3A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eys -

(-) 		no annotation 4 LEU B  66
ARG B 182
ILE B 167
PHE B 181
 None
 1.10A 5kirB-6eysB:
undetectable		 5kirB-6eysB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f2t -

(-) 		no annotation 4 LEU A 175
ARG A 171
ILE A 495
PHE A 170
 None
 1.16A 5kirB-6f2tA:
undetectable		 5kirB-6f2tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fa5 PUTATIVE MRNA
SPLICING FACTOR

(Chaetomium
thermophilum) 		no annotation 4 LEU A 334
ARG A 303
ILE A 330
PHE A 306
 None
 1.04A 5kirB-6fa5A:
undetectable		 5kirB-6fa5A:
10.60