SIMILAR PATTERNS OF AMINO ACIDS FOR 5KBW_B_RBFB201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a4s | BETAINE ALDEHYDEDEHYDROGENASE (Gadus morhua) |
PF00171(Aldedh) | 5 | GLY A 265ALA A 164ASN A 166VAL A 296LYS A 175 | None | 1.37A | 5kbwB-1a4sA:undetectable | 5kbwB-1a4sA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b65 | PROTEIN(AMINOPEPTIDASE) (Ochrobactrumanthropi) |
PF03576(Peptidase_S58) | 5 | GLU A 144ASP A 290ASN A 218ALA A 339VAL A 332 | None | 1.35A | 5kbwB-1b65A:0.0 | 5kbwB-1b65A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bvy | PROTEIN (CYTOCHROMEP450 BM-3) (Bacillusmegaterium) |
PF00258(Flavodoxin_1) | 5 | LEU F 516ASP F 586ALA F 497VAL F 529TYR F 564 | None | 1.17A | 5kbwB-1bvyF:undetectable | 5kbwB-1bvyF:24.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g7o | GLUTAREDOXIN 2 (Escherichiacoli) |
PF04399(Glutaredoxin2_C)PF13417(GST_N_3) | 5 | GLU A 87ASP A 172ALA A 153VAL A 194TYR A 197 | None | 1.31A | 5kbwB-1g7oA:undetectable | 5kbwB-1g7oA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gqa | CYTOCHROME C' (Rhodobactersphaeroides) |
PF01322(Cytochrom_C_2) | 5 | GLU A 31LYS A 29GLY A 22ALA A 101VAL A 115 | None | 1.32A | 5kbwB-1gqaA:undetectable | 5kbwB-1gqaA:24.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h74 | HOMOSERINE KINASE (Methanocaldococcusjannaschii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | GLU A 185GLY A 92ALA A 16ASN A 141ASN A 17 | NoneADP A 400 (-3.7A)ILE A 500 ( 4.0A)ILE A 500 (-4.2A)ILE A 500 (-2.8A) | 1.21A | 5kbwB-1h74A:0.2 | 5kbwB-1h74A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j7h | HYPOTHETICAL PROTEINHI0719 (Haemophilusinfluenzae) |
PF01042(Ribonuc_L-PSP) | 5 | LEU A 121ASN A 57ALA A 49VAL A 88TYR A 92 | None | 1.35A | 5kbwB-1j7hA:0.8 | 5kbwB-1j7hA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1khd | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Pectobacteriumcarotovorum) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 5 | LEU A 286ASP A 295GLY A 294ALA A 334VAL A 302 | None | 1.33A | 5kbwB-1khdA:0.0 | 5kbwB-1khdA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrw | HYPOTHETICALPROTEIN, HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacillussubtilis) |
PF08282(Hydrolase_3) | 5 | GLU A 132GLY A 10ALA A 278ASN A 23VAL A 19 | None CA A 903 ( 4.4A)NoneNoneNone | 1.25A | 5kbwB-1nrwA:undetectable | 5kbwB-1nrwA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p2f | RESPONSE REGULATOR (Thermotogamaritima) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 5 | ASP A 131GLY A 121ALA A 109VAL A 98TYR A 97 | None | 1.36A | 5kbwB-1p2fA:0.0 | 5kbwB-1p2fA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p4t | OUTER MEMBRANEPROTEIN NSPA (Neisseriameningitidis) |
PF02462(Opacity) | 5 | LEU A 61GLY A 145ALA A 24VAL A 142ASN A 51 | NoneNoneCXE A 500 ( 4.1A)CXE A 500 ( 4.5A)None | 1.24A | 5kbwB-1p4tA:undetectable | 5kbwB-1p4tA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgj | CITRATE LYASE, BETASUBUNIT (Deinococcusradiodurans) |
PF03328(HpcH_HpaI) | 5 | LEU A 128GLY A 105ASN A 136ALA A 181VAL A 146 | None | 1.20A | 5kbwB-1sgjA:undetectable | 5kbwB-1sgjA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdq | TENASCIN-R (Rattusnorvegicus) |
PF00041(fn3) | 5 | GLY A 163ASN A 181ALA A 178VAL A 126TYR A 128 | None | 1.28A | 5kbwB-1tdqA:undetectable | 5kbwB-1tdqA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xog | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | LEU A 324ASP A 295GLY A 299ASN A 345TYR A 318 | None | 1.36A | 5kbwB-1xogA:undetectable | 5kbwB-1xogA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yck | PEPTIDOGLYCANRECOGNITION PROTEIN (Homo sapiens) |
PF01510(Amidase_2) | 5 | LEU A 162ASP A 151GLY A 148ALA A 127TYR A 172 | None | 1.18A | 5kbwB-1yckA:undetectable | 5kbwB-1yckA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yga | HYPOTHETICAL 37.9KDA PROTEIN INBIO3-HXT17INTERGENIC REGION (Saccharomycescerevisiae) |
PF01263(Aldose_epim) | 5 | LEU A 232GLY A 303ASN A 180ALA A 268TYR A 289 | None | 1.27A | 5kbwB-1ygaA:undetectable | 5kbwB-1ygaA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yni | SUCCINYLARGININEDIHYDROLASE (Escherichiacoli) |
PF04996(AstB) | 5 | GLY A 175ASN A 178ALA A 364VAL A 108ASN A 306 | NoneNoneNoneNoneSUG A1001 ( 4.1A) | 1.33A | 5kbwB-1yniA:undetectable | 5kbwB-1yniA:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z45 | GAL10 BIFUNCTIONALPROTEIN (Saccharomycescerevisiae) |
PF01263(Aldose_epim)PF16363(GDP_Man_Dehyd) | 5 | LEU A 591GLY A 661ASN A 541ALA A 626TYR A 647 | NoneNoneNoneNoneGAL A 700 (-4.1A) | 1.19A | 5kbwB-1z45A:undetectable | 5kbwB-1z45A:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2auk | DNA-DIRECTED RNAPOLYMERASE BETA'CHAIN (Escherichiacoli) |
no annotation | 5 | LEU A 45ASP A 68GLY A 69ALA A 73VAL A 78 | None | 1.40A | 5kbwB-2aukA:undetectable | 5kbwB-2aukA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3i | OVOTRANSFERRIN (Gallus gallus) |
PF00405(Transferrin) | 5 | ASP A 572GLY A 573ASN A 444ALA A 437LYS A 451 | None | 1.39A | 5kbwB-2d3iA:undetectable | 5kbwB-2d3iA:14.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3l | GLUCAN1,4-ALPHA-MALTOHEXAOSIDASE (Bacillus sp.707) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 5 | GLY A 96ASN A 94ALA A 88VAL A 42ASN A 28 | None | 1.40A | 5kbwB-2d3lA:undetectable | 5kbwB-2d3lA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fj0 | CARBOXYLIC ESTERHYDROLASE (Manduca sexta) |
PF00135(COesterase) | 5 | LEU A 183ASP A 198GLY A 195ASN A 193ASN A 271 | None | 1.39A | 5kbwB-2fj0A:undetectable | 5kbwB-2fj0A:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gw3 | KAEDE (Trachyphylliageoffroyi) |
PF01353(GFP) | 5 | LEU A 210LYS A 209ASP A 28GLY A 27ALA A 60 | CR8 A 63 ( 3.8A)NoneNoneNoneNone | 1.40A | 5kbwB-2gw3A:undetectable | 5kbwB-2gw3A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwn | DIHYDROOROTASE (Porphyromonasgingivalis) |
PF01979(Amidohydro_1) | 5 | GLU A 321LYS A 74GLY A 333ALA A 83VAL A 64 | None | 1.21A | 5kbwB-2gwnA:undetectable | 5kbwB-2gwnA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hae | MALATEOXIDOREDUCTASE (Thermotogamaritima) |
PF00390(malic)PF03949(Malic_M) | 5 | GLU A 287GLY A 304ASN A 283ASN A 314VAL A 162 | None | 1.38A | 5kbwB-2haeA:undetectable | 5kbwB-2haeA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0r | CALPAIN-9 (Homo sapiens) |
PF00648(Peptidase_C2) | 5 | LEU A 229GLY A 202ASN A 335ALA A 112ASN A 109 | None | 1.40A | 5kbwB-2p0rA:undetectable | 5kbwB-2p0rA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qyt | 2-DEHYDROPANTOATE2-REDUCTASE (Porphyromonasgingivalis) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | ASP A 118ASN A 115ALA A 206VAL A 287TYR A 286 | None | 1.28A | 5kbwB-2qytA:1.5 | 5kbwB-2qytA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qyt | 2-DEHYDROPANTOATE2-REDUCTASE (Porphyromonasgingivalis) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | GLY A 116ASN A 115ALA A 206VAL A 287TYR A 286 | None | 1.30A | 5kbwB-2qytA:1.5 | 5kbwB-2qytA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z4t | BETA-GALACTOSIDEALPHA-2,6-SIALYLTRANSFERASE (Photobacteriumsp. JT-ISH-224) |
PF11477(PM0188) | 5 | ASP A 231GLY A 233ALA A 448VAL A 485TYR A 237 | NoneGOL A3004 (-3.3A)NoneNoneNone | 1.35A | 5kbwB-2z4tA:undetectable | 5kbwB-2z4tA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayr | ENDOGLUCANASE (Piromycesrhizinflatus) |
PF00150(Cellulase) | 5 | GLU A 12GLY A 102ASN A 63VAL A 95TYR A 99 | None | 1.22A | 5kbwB-3ayrA:undetectable | 5kbwB-3ayrA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctz | XAA-PROAMINOPEPTIDASE 1 (Homo sapiens) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 5 | ASP A 337GLY A 417VAL A 377TYR A 420ASN A 219 | None | 1.39A | 5kbwB-3ctzA:undetectable | 5kbwB-3ctzA:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3l | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Homo sapiens) |
PF00305(Lipoxygenase) | 5 | GLY A 235ASN A 237ALA A 557ASN A 556TYR A 230 | None | 1.40A | 5kbwB-3d3lA:1.4 | 5kbwB-3d3lA:15.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 5 | GLU A 29ASP A 241GLY A 284ALA A 37ASN A 38 | None | 1.40A | 5kbwB-3ewmA:undetectable | 5kbwB-3ewmA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gpi | NAD-DEPENDENTEPIMERASE/DEHYDRATASE (Methylobacillusflagellatus) |
PF13460(NAD_binding_10) | 5 | LEU A 94ASN A 89ALA A 7VAL A 102TYR A 145 | None | 1.30A | 5kbwB-3gpiA:undetectable | 5kbwB-3gpiA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hj6 | FRUCTOKINASE (Halothermothrixorenii) |
PF00294(PfkB) | 5 | LEU A 67ASP A 287GLY A 284ALA A 276ASN A 299 | None | 1.25A | 5kbwB-3hj6A:undetectable | 5kbwB-3hj6A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hj6 | FRUCTOKINASE (Halothermothrixorenii) |
PF00294(PfkB) | 5 | LEU A 67GLY A 284ALA A 276ASN A 299ASN A 63 | None | 1.38A | 5kbwB-3hj6A:undetectable | 5kbwB-3hj6A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1i | HOMOSERINEO-ACETYLTRANSFERASE (Bacillusanthracis) |
PF00561(Abhydrolase_1) | 5 | LYS A 361ASN A 367ALA A 147VAL A 307TYR A 336 | None | 1.28A | 5kbwB-3i1iA:undetectable | 5kbwB-3i1iA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ke6 | PROTEINRV1364C/MT1410 (Mycobacteriumtuberculosis) |
PF07228(SpoIIE)PF13581(HATPase_c_2) | 5 | LEU A 304ASP A 211GLY A 210ALA A 229VAL A 222 | None MN A 2 ( 2.5A)NoneNoneNone | 1.29A | 5kbwB-3ke6A:undetectable | 5kbwB-3ke6A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzh | PROBABLE SUGARKINASE (Clostridiumperfringens) |
PF00294(PfkB) | 5 | GLU A 315ASP A 229GLY A 230ASN A 285VAL A 247 | None | 1.36A | 5kbwB-3kzhA:undetectable | 5kbwB-3kzhA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0w | ABC BRANCHED CHAINAMINO ACID FAMILYTRANSPORTER,PERIPLASMIC LIGANDBINDING PROTEIN (Paraburkholderiaxenovorans) |
PF13458(Peripla_BP_6) | 6 | LEU A 314LYS A 315ASP A 339ALA A 96VAL A 51TYR A 307 | None | 1.31A | 5kbwB-3n0wA:undetectable | 5kbwB-3n0wA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne7 | ACETYLTRANSFERASE (Thermoplasmaacidophilum) |
PF00583(Acetyltransf_1) | 5 | GLU A 112LEU A 125GLY A 142ASN A 141VAL A 145 | NoneBME A 162 ( 3.9A)NoneGOL A 165 (-3.0A)None | 1.20A | 5kbwB-3ne7A:undetectable | 5kbwB-3ne7A:25.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3niw | HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacteroidesthetaiotaomicron) |
PF08282(Hydrolase_3) | 5 | LEU A 14ASP A 223GLY A 218ALA A 260ASN A 25 | None MG A 278 ( 4.3A)NoneNoneNone | 1.25A | 5kbwB-3niwA:undetectable | 5kbwB-3niwA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nnm | CURA (Lyngbyamajuscula) |
PF05721(PhyH) | 5 | GLU A 43LEU A 37ALA A 101ASN A 100VAL A 76 | NoneNoneFMT A 750 ( 4.0A)NoneNone | 1.31A | 5kbwB-3nnmA:undetectable | 5kbwB-3nnmA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o5c | CYTOCHROME C551PEROXIDASE (Shewanellaoneidensis) |
PF00034(Cytochrom_C)PF03150(CCP_MauG) | 5 | GLU A 36LEU A 42LYS A 39ALA A 143VAL A 154 | None | 0.96A | 5kbwB-3o5cA:undetectable | 5kbwB-3o5cA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oao | UNCHARACTERIZEDPROTEIN FROM DUF2059FAMILY (Pseudomonasaeruginosa) |
PF09832(DUF2059) | 5 | ASP A 95GLY A 99ALA A 51VAL A 56TYR A 59 | NoneNonePO4 A 2 ( 4.2A)NoneNone | 1.28A | 5kbwB-3oaoA:undetectable | 5kbwB-3oaoA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE ALPHA-SUBUNIT6-PHOSPHOFRUCTO-1-KINASE BETA-SUBUNIT (Komagataellapastoris) |
PF00365(PFK) | 5 | GLU A 382GLY B 471ALA B 475VAL B 245ASN B 720 | None | 1.21A | 5kbwB-3opyA:undetectable | 5kbwB-3opyA:12.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p5n | RIBOFLAVIN UPTAKEPROTEIN (Staphylococcusaureus) |
PF12822(ECF_trnsprt) | 5 | ASP A 81GLY A 84ASN A 88ASN A 131ASN A 164 | RBF A 190 (-3.0A)RBF A 190 (-3.1A)RBF A 190 ( 4.9A)RBF A 190 (-3.6A)RBF A 190 (-3.3A) | 0.65A | 5kbwB-3p5nA:24.1 | 5kbwB-3p5nA:33.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p5n | RIBOFLAVIN UPTAKEPROTEIN (Staphylococcusaureus) |
PF12822(ECF_trnsprt) | 5 | ASP A 81GLY A 84ASN A 88ASN A 131LYS A 167 | RBF A 190 (-3.0A)RBF A 190 (-3.1A)RBF A 190 ( 4.9A)RBF A 190 (-3.6A)RBF A 190 (-3.2A) | 0.73A | 5kbwB-3p5nA:24.1 | 5kbwB-3p5nA:33.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p5n | RIBOFLAVIN UPTAKEPROTEIN (Staphylococcusaureus) |
PF12822(ECF_trnsprt) | 5 | LEU A 42GLY A 84ASN A 88ASN A 131ASN A 164 | RBF A 190 (-4.6A)RBF A 190 (-3.1A)RBF A 190 ( 4.9A)RBF A 190 (-3.6A)RBF A 190 (-3.3A) | 0.49A | 5kbwB-3p5nA:24.1 | 5kbwB-3p5nA:33.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p5n | RIBOFLAVIN UPTAKEPROTEIN (Staphylococcusaureus) |
PF12822(ECF_trnsprt) | 5 | LEU A 42GLY A 84ASN A 88ASN A 131LYS A 167 | RBF A 190 (-4.6A)RBF A 190 (-3.1A)RBF A 190 ( 4.9A)RBF A 190 (-3.6A)RBF A 190 (-3.2A) | 0.56A | 5kbwB-3p5nA:24.1 | 5kbwB-3p5nA:33.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3prx | COBRA VENOM FACTOR (Naja kaouthia) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 5 | LEU B 567ASP B 553GLY B 552ALA B 803VAL B 789 | None | 1.41A | 5kbwB-3prxB:undetectable | 5kbwB-3prxB:7.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pw9 | UPF0603 PROTEINAT1G54780,CHLOROPLASTIC (Arabidopsisthaliana) |
PF04536(TPM_phosphatase) | 5 | LEU A 122GLY A 166ASN A 131ALA A 219VAL A 189 | None | 1.26A | 5kbwB-3pw9A:1.6 | 5kbwB-3pw9A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r5t | FERRIC VIBRIOBACTINABC TRANSPORTER,PERIPLASMIC FERRICVIBRIOBACTIN-BINDINGPROTEIN (Vibrio cholerae) |
PF01497(Peripla_BP_2) | 5 | ASP A 274ALA A 255ASN A 194VAL A 196TYR A 198 | None | 1.44A | 5kbwB-3r5tA:undetectable | 5kbwB-3r5tA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ram | HMRA PROTEIN (Staphylococcusaureus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | LEU A 123ASP A 147GLY A 144ALA A 136VAL A 320 | None | 1.20A | 5kbwB-3ramA:undetectable | 5kbwB-3ramA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Sus scrofa) |
PF00305(Lipoxygenase) | 5 | GLY A 236ASN A 238ALA A 558ASN A 557TYR A 231 | None | 1.39A | 5kbwB-3rdeA:1.8 | 5kbwB-3rdeA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Sus scrofa) |
PF00305(Lipoxygenase) | 5 | GLY A 236ASN A 238ALA A 558ASN A 557VAL A 219 | None | 1.38A | 5kbwB-3rdeA:1.8 | 5kbwB-3rdeA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ta6 | TRIOSEPHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00121(TIM) | 5 | GLU A 172LEU A 214GLY A 239ASN A 10ALA A 42 | None | 1.27A | 5kbwB-3ta6A:undetectable | 5kbwB-3ta6A:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ucn | CARBONIC ANHYDRASE (Coccomyxa sp.PA) |
PF00484(Pro_CA) | 5 | LEU A 74GLY A 112ASN A 157VAL A 133ASN A 73 | None | 1.24A | 5kbwB-3ucnA:undetectable | 5kbwB-3ucnA:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v98 | ARACHIDONATE5-LIPOXYGENASE (Homo sapiens) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | GLY A 239ASN A 241ALA A 567ASN A 566TYR A 234 | None | 1.36A | 5kbwB-3v98A:1.2 | 5kbwB-3v98A:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a01 | PROTONPYROPHOSPHATASE (Vigna radiata) |
PF03030(H_PPase) | 5 | ASP A 269GLY A 511ALA A 164ASN A 284VAL A 281 | MG A1768 ( 3.9A)NoneNoneNoneNone | 1.39A | 5kbwB-4a01A:1.9 | 5kbwB-4a01A:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aq4 | SN-GLYCEROL-3-PHOSPHATE-BINDINGPERIPLASMIC PROTEINUGPB (Escherichiacoli) |
PF13416(SBP_bac_8) | 5 | GLU A 176ASN A 191VAL A 101TYR A 105ASN A 279 | None | 1.12A | 5kbwB-4aq4A:undetectable | 5kbwB-4aq4A:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhd | SERINEHYDROXYMETHYLTRANSFERASE (Methanocaldococcusjannaschii) |
PF00464(SHMT) | 5 | LYS A 226ASP A 196GLY A 197ALA A 205VAL A 235 | None | 1.38A | 5kbwB-4bhdA:undetectable | 5kbwB-4bhdA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bnd | ALPHA-PHOSPHOGLUCOMUTASE (Lactococcuslactis) |
PF03332(PMM) | 5 | LEU B 13ASP B 220GLY B 211ASN B 11ALA B 240 | NoneNoneNoneNoneGOL B1253 ( 2.6A) | 1.36A | 5kbwB-4bndB:undetectable | 5kbwB-4bndB:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bnd | ALPHA-PHOSPHOGLUCOMUTASE (Lactococcuslactis) |
PF03332(PMM) | 5 | LEU B 13ASP B 220GLY B 211ASN B 11TYR B 209 | None | 1.32A | 5kbwB-4bndB:undetectable | 5kbwB-4bndB:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cag | POLYSACCHARIDE LYASEFAMILY 11 PROTEIN (Bacilluslicheniformis) |
PF01839(FG-GAP) | 5 | ASP A 551GLY A 572ASN A 377ALA A 405VAL A 337 | NoneNone CA A 608 (-2.9A)NoneNone | 1.42A | 5kbwB-4cagA:undetectable | 5kbwB-4cagA:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dzh | AMIDOHYDROLASE (Xanthomonascampestris) |
PF01979(Amidohydro_1) | 5 | GLU A 373ASP A 367GLY A 366ALA A 311ASN A 309 | None | 1.16A | 5kbwB-4dzhA:undetectable | 5kbwB-4dzhA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fj6 | GLYCOSIDE HYDROLASEFAMILY 33, CANDIDATESIALIDASE (Parabacteroidesdistasonis) |
PF13859(BNR_3)PF14873(BNR_assoc_N) | 5 | LEU A 440GLY A 416ALA A 447ASN A 468ASN A 409 | None | 1.23A | 5kbwB-4fj6A:undetectable | 5kbwB-4fj6A:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ggv | CYTOCHROME P450SUPERFAMILY PROTEIN (Streptomyceshimastatinicus) |
PF00067(p450) | 5 | LEU A 188GLY A 194ALA A 230VAL A 143ASN A 231 | None | 1.12A | 5kbwB-4ggvA:undetectable | 5kbwB-4ggvA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7a | CRISPR-ASSOCIATEDPROTEIN CSE2 (Thermusthermophilus) |
PF09485(CRISPR_Cse2) | 5 | LEU A 131ASP A 75GLY A 125ALA A 83VAL A 119 | None | 1.26A | 5kbwB-4h7aA:undetectable | 5kbwB-4h7aA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jkl | BETA-GLUCURONIDASE (Streptococcusagalactiae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 5 | GLU A 219GLY A 344ASN A 244VAL A 401ASN A 283 | None | 1.39A | 5kbwB-4jklA:undetectable | 5kbwB-4jklA:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oya | ADENYLATE CYCLASETYPE 10 (Homo sapiens) |
PF00211(Guanylate_cyc) | 5 | LEU A 345LYS A 334GLY A 98ALA A 414VAL A 391 | None | 1.28A | 5kbwB-4oyaA:undetectable | 5kbwB-4oyaA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9n | CARBOXYLESTERASE (Sulfolobusshibatae) |
PF07859(Abhydrolase_3) | 5 | LEU A 175GLY A 153ASN A 155ALA A 161TYR A 76 | None | 1.08A | 5kbwB-4p9nA:1.4 | 5kbwB-4p9nA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6k | BNR/ASP-BOX REPEATPROTEIN (Bacteroidescaccae) |
PF13088(BNR_2)PF14873(BNR_assoc_N) | 5 | LEU A 460GLY A 436ALA A 467ASN A 488ASN A 429 | None | 1.26A | 5kbwB-4q6kA:undetectable | 5kbwB-4q6kA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkc | AROMATIC AMINO ACIDAMINOTRANSFERASE (Psychrobactersp. B6) |
PF00155(Aminotran_1_2) | 5 | LEU A 81ASN A 247VAL A 311TYR A 312ASN A 242 | NO3 A 404 (-3.8A)NoneNoneNoneNone | 1.38A | 5kbwB-4rkcA:undetectable | 5kbwB-4rkcA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xf7 | CARBOHYDRATE/PYRIMIDINE KINASE, PFKBFAMILY (Thermococcuskodakarensis) |
no annotation | 5 | LEU A 77ASP A 219GLY A 216VAL A 10LYS A 16 | INS A 301 ( 4.8A)INS A 301 (-2.7A)ACP A 302 (-3.9A)INS A 301 ( 4.8A)None | 1.33A | 5kbwB-4xf7A:undetectable | 5kbwB-4xf7A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z11 | AURONE SYNTHASE (Coreopsisgrandiflora) |
PF00264(Tyrosinase)PF12142(PPO1_DWL)PF12143(PPO1_KFDV) | 5 | GLU A 248LEU A 120GLY A 228VAL A 231ASN A 331 | None | 1.38A | 5kbwB-4z11A:undetectable | 5kbwB-4z11A:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8i | PEPTIDOGLYCANRECOGNITION PROTEIN3 (Branchiostomabelcheri) |
PF01510(Amidase_2) | 5 | LEU A 215ASP A 204GLY A 201ALA A 180TYR A 225 | None | 1.15A | 5kbwB-4z8iA:undetectable | 5kbwB-4z8iA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a05 | ALDOSE-ALDOSEOXIDOREDUCTASE (Caulobactervibrioides) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | LEU A 127GLY A 130ALA A 107VAL A 79TYR A 78 | None | 1.26A | 5kbwB-5a05A:undetectable | 5kbwB-5a05A:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3i | CYTOCHROME C PRIME (Hydrogenophilusthermoluteolus) |
PF01322(Cytochrom_C_2) | 5 | LEU A 101ASP A 109GLY A 108ALA A 45VAL A 30 | None | 1.40A | 5kbwB-5b3iA:2.6 | 5kbwB-5b3iA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | ASP A 170GLY A 459ALA A 39VAL A 769ASN A 591 | MO A1002 ( 2.6A)BSY A1013 ( 3.0A)NoneMGD A1003 ( 4.1A)None | 1.19A | 5kbwB-5chcA:undetectable | 5kbwB-5chcA:11.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dn6 | ATP SYNTHASE GAMMACHAIN (Paracoccusdenitrificans) |
PF00231(ATP-synt) | 5 | LYS G 212ASP G 220ASN G 215ALA G 58VAL G 52 | None | 1.29A | 5kbwB-5dn6G:undetectable | 5kbwB-5dn6G:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dwf | PEPTIDOGLYCANRECOGNITION PROTEIN1 (Camelusdromedarius) |
PF01510(Amidase_2) | 5 | LEU A 159ASP A 148GLY A 145ALA A 124TYR A 169 | None | 1.26A | 5kbwB-5dwfA:undetectable | 5kbwB-5dwfA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idi | 1,4-BETA-D-GLUCANGLUCOHYDROLASE (Thermotoganeapolitana) |
PF00232(Glyco_hydro_1) | 5 | GLU A 20ASN A 151VAL A 147TYR A 144ASN A 100 | None | 1.43A | 5kbwB-5idiA:undetectable | 5kbwB-5idiA:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j3u | PROTEIN KINASE A (Toxoplasmagondii) |
PF00027(cNMP_binding) | 5 | LEU A 160ASP A 170ASN A 175ALA A 180VAL A 267 | None | 1.23A | 5kbwB-5j3uA:undetectable | 5kbwB-5j3uA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxl | FLAGELLAR HOOKPROTEIN FLGE (Campylobacterjejuni) |
PF00460(Flg_bb_rod)PF06429(Flg_bbr_C)PF07196(Flagellin_IN)PF07559(FlaE) | 5 | ASP A 234GLY A 236ALA A 580ASN A 578TYR A 429 | None | 1.09A | 5kbwB-5jxlA:2.5 | 5kbwB-5jxlA:11.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mtz | RIBONUCLEASE Z (Saccharomycescerevisiae) |
PF13691(Lactamase_B_4) | 5 | GLU A 780LEU A 717LYS A 754ASP A 791VAL A 489 | None | 1.36A | 5kbwB-5mtzA:undetectable | 5kbwB-5mtzA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mtz | RIBONUCLEASE Z (Saccharomycescerevisiae) |
PF13691(Lactamase_B_4) | 5 | GLU A 780LEU A 717LYS A 754ASP A 791VAL A 491 | None | 1.33A | 5kbwB-5mtzA:undetectable | 5kbwB-5mtzA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5owx | GENOME POLYPROTEIN (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | GLY 1 132ALA 2 131VAL 1 129TYR 1 130LYS 2 80 | None | 1.23A | 5kbwB-5owx1:undetectable | 5kbwB-5owx1:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tzb | D-AMINOPEPTIDASE (Burkholderiasp. LK4) |
PF03576(Peptidase_S58) | 5 | GLU A 127ASP A 279ASN A 201ALA A 332VAL A 325 | None | 1.36A | 5kbwB-5tzbA:undetectable | 5kbwB-5tzbA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6f | LPXTG-MOTIF CELLWALL ANCHOR DOMAINPROTEIN (Mobiluncusmulieris) |
no annotation | 5 | GLU A 216LEU A 171LYS A 172ALA A 265VAL A 255 | None | 1.24A | 5kbwB-5u6fA:undetectable | 5kbwB-5u6fA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5urb | METHIONINE--TRNALIGASE (Acinetobacterbaumannii) |
PF08264(Anticodon_1)PF09334(tRNA-synt_1g) | 5 | ASP A 294GLY A 292ASN A 321ALA A 28ASN A 8 | NoneNone NA A 601 (-3.2A)NoneNone | 1.00A | 5kbwB-5urbA:2.2 | 5kbwB-5urbA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 5 | GLU A 796LEU A 803ASN A 765ALA A 772VAL A 533 | None | 1.43A | 5kbwB-5wugA:undetectable | 5kbwB-5wugA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7f | PUTATIVEO-METHYLTRANSFERASERV1220C (Mycobacteriumtuberculosis) |
PF01596(Methyltransf_3) | 5 | GLU A 18LEU A 49GLY A 208ALA A 201VAL A 162 | None | 0.99A | 5kbwB-5x7fA:undetectable | 5kbwB-5x7fA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmj | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Desulfovibriogigas) |
no annotation | 5 | GLU A 582LEU A 579GLY A 249ASN A 250ALA A 539 | None | 1.40A | 5kbwB-5xmjA:undetectable | 5kbwB-5xmjA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a8l | - (-) |
no annotation | 5 | GLY A 178ASN A 175ALA A 169VAL A 142TYR A 145 | None | 1.23A | 5kbwB-6a8lA:undetectable | 5kbwB-6a8lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bj9 | ACETYL-COAACETYLTRANSFERASE A (Ascaris suum) |
no annotation | 5 | GLU A 35LEU A 41LYS A 38GLY A 75ALA A 54 | None | 1.41A | 5kbwB-6bj9A:undetectable | 5kbwB-6bj9A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT B (Flavobacteriumjohnsoniae) |
no annotation | 5 | LEU B 646GLY B 649ASN B 665ASN B 630LYS B 627 | None | 1.25A | 5kbwB-6btmB:undetectable | 5kbwB-6btmB:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6en4 | SPLICING FACTOR 3BSUBUNIT 3SPLICING FACTOR 3BSUBUNIT 5 (Homo sapiens) |
no annotation | 5 | GLU B 59GLY A 858ASN A 859ASN A 885TYR A 807 | None | 1.33A | 5kbwB-6en4B:undetectable | 5kbwB-6en4B:18.23 |