SIMILAR PATTERNS OF AMINO ACIDS FOR 5KB5_A_ADNA401_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6j NITROGEN REGULATORY
IIA PROTEIN

(Escherichia
coli) 		PF00359
(PTS_EIIA_2) 		4 ASN A  15
LEU A  14
SER A  12
LEU A 110
 None
 1.25A 5kb5A-1a6jA:
undetectable		 5kb5A-1a6jA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bqg D-GLUCARATE
DEHYDRATASE

(Pseudomonas
putida) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASN A 295
LEU A 317
SER A 346
LEU A 154
 None
 1.38A 5kb5A-1bqgA:
0.4		 5kb5A-1bqgA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dce PROTEIN (RAB
GERANYLGERANYLTRANSF
ERASE ALPHA SUBUNIT)

(Rattus
norvegicus) 		PF01239
(PPTA)
PF07711
(RabGGT_insert) 		4 ASN A 496
LEU A 498
SER A 494
LEU A 513
 None
 1.29A 5kb5A-1dceA:
0.0		 5kb5A-1dceA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 ASN A 515
LEU A 519
SER A 517
LEU A 481
 None
 1.33A 5kb5A-1hn0A:
undetectable		 5kb5A-1hn0A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jct GLUCARATE
DEHYDRATASE

(Escherichia
coli) 		PF13378
(MR_MLE_C) 		4 ASN A 289
LEU A 311
SER A 340
LEU A 148
 GKR  A 499 ( 2.9A)
None
None
None
 1.29A 5kb5A-1jctA:
1.0		 5kb5A-1jctA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 ASN A1121
LEU A1123
SER A1139
LEU A1136
 None
 1.05A 5kb5A-1jl5A:
undetectable		 5kb5A-1jl5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 ASN A1267
LEU A1269
SER A1285
LEU A1282
 None
 1.08A 5kb5A-1jl5A:
undetectable		 5kb5A-1jl5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mi1 NEUROBEACHIN

(Homo sapiens) 		PF02138
(Beach)
PF14844
(PH_BEACH) 		4 ASN A2286
LEU A2475
SER A2477
LEU A2314
 None
 1.39A 5kb5A-1mi1A:
undetectable		 5kb5A-1mi1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgu ACTIN INTERACTING
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 ASN A 589
LEU A 591
SER A 600
LEU A 350
 None
 1.37A 5kb5A-1pguA:
0.0		 5kb5A-1pguA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpw PORCINE HEMOGLOBIN
(ALPHA SUBUNIT)

(Sus scrofa) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 650 ( 4.8A)
 0.87A 5kb5A-1qpwA:
0.1		 5kb5A-1qpwA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uhu PRODUCT OF RIKEN
CDNA 3110009E22

(Mus musculus) 		PF01140
(Gag_MA) 		4 ASN A  25
LEU A  26
SER A  21
LEU A  89
 None
 1.15A 5kb5A-1uhuA:
undetectable		 5kb5A-1uhuA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v2d GLUTAMINE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 ASN A 159
LEU A 157
SER A 190
LEU A  94
 PLP  A 510 (-3.3A)
None
None
None
 1.27A 5kb5A-1v2dA:
3.6		 5kb5A-1v2dA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vmd METHYLGLYOXAL
SYNTHASE

(Thermotoga
maritima) 		PF02142
(MGS) 		4 ASN A  37
LEU A  41
SER A  35
LEU A  56
 None
 1.31A 5kb5A-1vmdA:
undetectable		 5kb5A-1vmdA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xec DECORIN

(Bos taurus) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		4 ASN A 110
LEU A 112
SER A 108
LEU A 126
 None
 1.34A 5kb5A-1xecA:
undetectable		 5kb5A-1xecA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zyb TRANSCRIPTION
REGULATOR, CRP
FAMILY

(Bacteroides
thetaiotaomicron) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 ASN A 190
LEU A 152
SER A 192
LEU A 180
 None
 1.04A 5kb5A-1zybA:
undetectable		 5kb5A-1zybA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aip PROTEIN C ACTIVATOR

(Agkistrodon
contortrix) 		PF00089
(Trypsin) 		4 ASN A 161
LEU A 163
SER A 134
LEU A 181
 None
None
SO4  A 302 (-2.3A)
None
 1.37A 5kb5A-2aipA:
undetectable		 5kb5A-2aipA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ba0 ARCHAEAL EXOSOME RNA
BINDING PROTEIN RRP4

(Archaeoglobus
fulgidus) 		PF00575
(S1)
PF14382
(ECR1_N)
PF15985
(KH_6) 		4 ASN A  90
LEU A  85
SER A  88
LEU A 114
 None
 1.10A 5kb5A-2ba0A:
undetectable		 5kb5A-2ba0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bex RIBONUCLEASE
INHIBITOR

(Homo sapiens) 		PF13516
(LRR_6) 		4 ASN A 407
LEU A 409
SER A 405
LEU A 431
 None
 1.34A 5kb5A-2bexA:
undetectable		 5kb5A-2bexA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF16073
(SAT) 		4 ASN B 418
LEU B 339
SER B 342
LEU B 421
 None
 1.34A 5kb5A-2pffB:
undetectable		 5kb5A-2pffB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsd UNCHARACTERIZED
CONSERVED PROTEIN

(Idiomarina
loihiensis) 		PF07566
(DUF1543) 		4 ASN A   6
LEU A  71
SER A  73
LEU A 150
 None
 1.29A 5kb5A-2qsdA:
undetectable		 5kb5A-2qsdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v95 CORTICOSTEROID-BINDI
NG GLOBULIN

(Rattus
norvegicus) 		PF00079
(Serpin) 		4 ASN A 169
LEU A 282
SER A  44
LEU A  23
 None
 1.34A 5kb5A-2v95A:
undetectable		 5kb5A-2v95A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vuw SERINE/THREONINE-PRO
TEIN KINASE HASPIN

(Homo sapiens) 		PF12330
(Haspin_kinase) 		4 ASN A 741
LEU A 745
SER A 786
LEU A 791
 None
None
None
DMS  A1802 ( 4.6A)
 1.36A 5kb5A-2vuwA:
undetectable		 5kb5A-2vuwA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxb DNA REPAIR PROTEIN
RHP9

(Schizosaccharomyces
pombe) 		PF00533
(BRCT) 		4 ASN A  85
LEU A 158
SER A  83
LEU A  51
 None
 1.28A 5kb5A-2vxbA:
undetectable		 5kb5A-2vxbA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wya HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 ASN A 378
LEU A 374
SER A 385
LEU A 372
 None
 1.35A 5kb5A-2wyaA:
undetectable		 5kb5A-2wyaA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0s PYRUVATE PHOSPHATE
DIKINASE

(Trypanosoma
brucei) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 ASN A 112
LEU A  92
SER A  94
LEU A 208
 None
 1.35A 5kb5A-2x0sA:
undetectable		 5kb5A-2x0sA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3h K5 LYASE

(Escherichia
virus K1-5) 		no annotation 4 ASN A 214
LEU A 207
SER A 185
LEU A 182
 None
 1.27A 5kb5A-2x3hA:
undetectable		 5kb5A-2x3hA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xot AMPHOTERIN-INDUCED
PROTEIN 1

(Mus musculus) 		PF07679
(I-set)
PF13855
(LRR_8) 		4 ASN A 195
LEU A 197
SER A 193
LEU A 216
 None
 1.34A 5kb5A-2xotA:
undetectable		 5kb5A-2xotA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
1, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN B 382
LEU B 384
SER B 406
LEU B 403
 None
None
NAG  A 831 (-3.0A)
None
 1.18A 5kb5A-2z7xB:
undetectable		 5kb5A-2z7xB:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
1, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN B 433
LEU B 435
SER B 431
LEU B 450
 None
None
NAG  A 831 (-3.6A)
None
 1.35A 5kb5A-2z7xB:
undetectable		 5kb5A-2z7xB:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN A 467
LEU A 469
SER A 465
LEU A 482
 None
 1.39A 5kb5A-2z7xA:
undetectable		 5kb5A-2z7xA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN A 467
LEU A 469
SER A 485
LEU A 482
 None
 1.15A 5kb5A-2z7xA:
undetectable		 5kb5A-2z7xA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z81 TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13306
(LRR_5)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 397
LEU A 399
SER A 395
LEU A 418
 None
None
NAG  A 811 ( 4.1A)
None
 1.38A 5kb5A-2z81A:
undetectable		 5kb5A-2z81A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z81 TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13306
(LRR_5)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 397
LEU A 399
SER A 421
LEU A 418
 None
None
NAG  A 811 (-3.4A)
None
 1.21A 5kb5A-2z81A:
undetectable		 5kb5A-2z81A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1j CELL CYCLE
CHECKPOINT PROTEIN
RAD1

(Homo sapiens) 		PF02144
(Rad1) 		4 ASN C  26
LEU C  21
SER C  28
LEU C 123
 None
 1.20A 5kb5A-3a1jC:
undetectable		 5kb5A-3a1jC:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN B 387
LEU B 389
SER B 411
LEU B 408
 None
None
NDG  B 971 (-2.7A)
None
 1.08A 5kb5A-3a79B:
undetectable		 5kb5A-3a79B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN B 413
LEU B 415
SER B 437
LEU B 457
 None
None
NAG  B 972 ( 4.2A)
None
 1.34A 5kb5A-3a79B:
undetectable		 5kb5A-3a79B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ciy TOLL-LIKE RECEPTOR 3

(Mus musculus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 ASN A 109
LEU A 111
SER A 132
LEU A 154
 None
 1.11A 5kb5A-3ciyA:
undetectable		 5kb5A-3ciyA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1a HEMOGLOBIN SUBUNIT
ALPHA-1/2

(Capra hircus) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 142 ( 4.8A)
 0.97A 5kb5A-3d1aA:
undetectable		 5kb5A-3d1aA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		4 ASN A 372
LEU A 374
SER A 390
LEU A 387
 None
 1.10A 5kb5A-3g06A:
undetectable		 5kb5A-3g06A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdj HEMOGLOBIN SUBUNIT
ALPHA

(Camelus
dromedarius) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 142 ( 4.7A)
 0.90A 5kb5A-3gdjA:
undetectable		 5kb5A-3gdjA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3god CAS1

(Pseudomonas
aeruginosa) 		PF01867
(Cas_Cas1) 		4 ASN A 299
LEU A 274
SER A 301
LEU A 236
 None
 1.35A 5kb5A-3godA:
undetectable		 5kb5A-3godA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7u ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		4 ASN A 228
LEU A 227
SER A 237
LEU A 209
 None
None
NAP  A 401 ( 4.8A)
NAP  A 401 (-3.8A)
 1.29A 5kb5A-3h7uA:
undetectable		 5kb5A-3h7uA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jav INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 1

(Rattus
norvegicus) 		PF00520
(Ion_trans)
PF01365
(RYDR_ITPR)
PF02815
(MIR)
PF08454
(RIH_assoc)
PF08709
(Ins145_P3_rec) 		4 ASN A 229
LEU A 111
SER A 227
LEU A   9
 None
 0.95A 5kb5A-3javA:
undetectable		 5kb5A-3javA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jck 26S PROTEASOME
REGULATORY SUBUNIT
RPN3

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF08375
(Rpn3_C) 		4 ASN A 280
LEU A 276
SER A 251
LEU A 257
 None
 1.18A 5kb5A-3jckA:
undetectable		 5kb5A-3jckA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l78 REGULATORY PROTEIN
SPX

(Streptococcus
mutans) 		PF03960
(ArsC) 		4 ASN A  86
LEU A  89
SER A  84
LEU A  79
 None
 1.18A 5kb5A-3l78A:
undetectable		 5kb5A-3l78A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll1 GRIFFITHSIN

(Griffithsia sp.
Q66D336) 		PF01419
(Jacalin) 		4 ASN A  71
LEU A  29
SER A  65
LEU A 114
 None
 1.29A 5kb5A-3ll1A:
undetectable		 5kb5A-3ll1A:
17.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae) 		PF00294
(PfkB) 		4 ASN A  14
LEU A  16
SER A  65
LEU A 133
 B4P  A 349 ( 4.0A)
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
 0.45A 5kb5A-3looA:
51.7		 5kb5A-3looA:
51.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzn GLUCARATE
DEHYDRATASE

(Chromohalobacter
salexigens) 		PF13378
(MR_MLE_C) 		4 ASN A 285
LEU A 307
SER A 336
LEU A 144
 None
None
None
ACT  A 452 ( 4.2A)
 1.28A 5kb5A-3mznA:
2.3		 5kb5A-3mznA:
22.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3otx ADENOSINE KINASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00294
(PfkB) 		4 ASN A  13
LEU A  15
SER A  64
LEU A 134
 AP5  A 346 (-4.1A)
AP5  A 346 (-4.4A)
NA  A 347 (-4.8A)
AP5  A 346 ( 4.4A)
 0.23A 5kb5A-3otxA:
50.2		 5kb5A-3otxA:
41.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qp5 CVIR TRANSCRIPTIONAL
REGULATOR

(Chromobacterium
violaceum) 		PF00196
(GerE)
PF03472
(Autoind_bind) 		4 ASN A  67
LEU A 104
SER A 145
LEU A  60
 None
 1.39A 5kb5A-3qp5A:
undetectable		 5kb5A-3qp5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s69 THROMBIN-LIKE ENZYME
DEFIBRASE

(Gloydius
saxatilis) 		PF00089
(Trypsin) 		4 ASN A 158
LEU A 160
SER A 131
LEU A 179
 None
 1.26A 5kb5A-3s69A:
undetectable		 5kb5A-3s69A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vre HEMOGLOBIN SUBUNIT
ALPHA

(Mammuthus
primigenius) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
HEM  A 201 ( 4.2A)
None
 1.24A 5kb5A-3vreA:
undetectable		 5kb5A-3vreA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 317
LEU A 319
SER A 341
LEU A 338
 None
 1.14A 5kb5A-3wpeA:
undetectable		 5kb5A-3wpeA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 529
LEU A 531
SER A 551
LEU A 548
 None
 1.15A 5kb5A-3wpeA:
undetectable		 5kb5A-3wpeA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwh (R)-AMINE
TRANSAMINASE

(Arthrobacter
sp. KNK168) 		PF01063
(Aminotran_4) 		4 ASN A 296
LEU A 273
SER A 292
LEU A 211
 None
 0.92A 5kb5A-3wwhA:
undetectable		 5kb5A-3wwhA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE

(Parageobacillus
thermoglucosidasius) 		PF00465
(Fe-ADH) 		4 ASN A 712
LEU A 689
SER A 714
LEU A 694
 None
 1.09A 5kb5A-3zdrA:
3.4		 5kb5A-3zdrA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ASN A 629
LEU A 631
SER A 706
LEU A 653
 None
 0.95A 5kb5A-4cakA:
undetectable		 5kb5A-4cakA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4di5 5-EPI-ARISTOLOCHENE
SYNTHASE

(Nicotiana
tabacum) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ASN A 149
LEU A 109
SER A 107
LEU A  64
 None
 1.39A 5kb5A-4di5A:
undetectable		 5kb5A-4di5A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB

(Pyrococcus
horikoshii) 		PF01139
(RtcB) 		4 ASN A 295
LEU A 195
SER A 237
LEU A 148
 None
 1.31A 5kb5A-4dwqA:
undetectable		 5kb5A-4dwqA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e72 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF11738
(DUF3298) 		4 ASN A  54
LEU A  52
SER A 107
LEU A  98
 None
 1.34A 5kb5A-4e72A:
undetectable		 5kb5A-4e72A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e7n SNAKE-VENOM
THROMBIN-LIKE ENZYME

(Gloydius halys) 		PF00089
(Trypsin) 		4 ASN A 161
LEU A 163
SER A 134
LEU A 181
 None
 1.17A 5kb5A-4e7nA:
undetectable		 5kb5A-4e7nA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4et7 EPHRIN TYPE-A
RECEPTOR 5

(Homo sapiens) 		PF01404
(Ephrin_lbd) 		4 ASN A 165
LEU A 114
SER A 116
LEU A 212
 None
 1.36A 5kb5A-4et7A:
undetectable		 5kb5A-4et7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 ASN A 869
LEU A 841
SER A 865
LEU A 832
 None
 1.29A 5kb5A-4fysA:
undetectable		 5kb5A-4fysA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hbk ALDO-KETO REDUCTASE
FAMILY 1, MEMBER B4
(ALDOSE REDUCTASE)

(Schistosoma
japonicum) 		PF00248
(Aldo_ket_red) 		4 ASN A 179
LEU A 108
SER A 155
LEU A 104
 None
 1.30A 5kb5A-4hbkA:
undetectable		 5kb5A-4hbkA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ija XYLR PROTEIN

(Staphylococcus
aureus) 		PF00480
(ROK)
PF01047
(MarR) 		4 ASN A 181
LEU A 218
SER A 183
LEU A 358
 K  A 507 (-3.0A)
None
None
None
 1.33A 5kb5A-4ijaA:
undetectable		 5kb5A-4ijaA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l6r SOLUBLE CYTOCHROME
B562 AND GLUCAGON
RECEPTOR CHIMERA

(Escherichia
coli;
Homo sapiens) 		PF00002
(7tm_2)
PF07361
(Cytochrom_B562) 		4 ASN A 174
LEU A 163
SER A 167
LEU A 411
 None
 1.24A 5kb5A-4l6rA:
undetectable		 5kb5A-4l6rA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu1 MAF-LIKE PROTEIN
YCEF

(Escherichia
coli) 		PF02545
(Maf) 		4 ASN A  87
LEU A  90
SER A 150
LEU A  74
 None
 1.30A 5kb5A-4lu1A:
undetectable		 5kb5A-4lu1A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxr PROTEIN TOLL

(Drosophila
melanogaster) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13306
(LRR_5)
PF13855
(LRR_8) 		4 ASN A 702
LEU A 704
SER A 722
LEU A 719
 None
 1.08A 5kb5A-4lxrA:
undetectable		 5kb5A-4lxrA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 132
LEU A 134
SER A 156
LEU A 153
 None
None
NAG  A 801 (-3.5A)
None
 1.11A 5kb5A-4m7eA:
undetectable		 5kb5A-4m7eA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o27 CALCIUM-BINDING
PROTEIN 39

(Homo sapiens) 		PF08569
(Mo25) 		4 ASN A  46
LEU A  19
SER A  44
LEU A  26
 None
 1.33A 5kb5A-4o27A:
undetectable		 5kb5A-4o27A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd3 NONMUSCLE MYOSIN
HEAVY CHAIN B,
ALPHA-ACTININ A
CHIMERA PROTEIN

(Dictyostelium
discoideum;
Homo sapiens) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 ASN A 104
LEU A 105
SER A 100
LEU A 705
 None
 1.17A 5kb5A-4pd3A:
0.5		 5kb5A-4pd3A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4peq RIBONUCLEASE/ANGIOGE
NIN INHIBITOR 1

(Bos taurus) 		PF13516
(LRR_6) 		4 ASN B 346
LEU B 348
SER B 344
LEU B 370
 None
 1.28A 5kb5A-4peqB:
undetectable		 5kb5A-4peqB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pq8 DESIGNED PROTEIN
OR465

(synthetic
construct) 		PF00560
(LRR_1)
PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 ASN A  80
LEU A  82
SER A 100
LEU A  97
 None
 1.13A 5kb5A-4pq8A:
undetectable		 5kb5A-4pq8A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psj OR464

(synthetic
construct) 		PF12354
(Internalin_N)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A  80
LEU A  82
SER A 100
LEU A  97
 None
 1.13A 5kb5A-4psjA:
undetectable		 5kb5A-4psjA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tzh LIC12234

(Leptospira
interrogans) 		PF13855
(LRR_8) 		4 ASN A 167
LEU A 169
SER A 165
LEU A 185
 None
 1.30A 5kb5A-4tzhA:
undetectable		 5kb5A-4tzhA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wp6 MRNA EXPORT PROTEIN

(Chaetomium
thermophilum) 		PF14580
(LRR_9) 		4 ASN A 297
LEU A 299
SER A 295
LEU A 318
 None
 1.39A 5kb5A-4wp6A:
undetectable		 5kb5A-4wp6A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5boe ENOLASE

(Staphylococcus
aureus) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 ASN A  18
LEU A  13
SER A  15
LEU A  36
 None
 1.37A 5kb5A-5boeA:
undetectable		 5kb5A-5boeA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epg ALDEHYDE OXIDASE

(Homo sapiens) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 ASN A 147
LEU A 144
SER A 347
LEU A 128
 None
 1.31A 5kb5A-5epgA:
undetectable		 5kb5A-5epgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr8 LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE PEPR1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 ASN A 732
LEU A 735
SER A 730
LEU A 722
 None
 1.09A 5kb5A-5gr8A:
undetectable		 5kb5A-5gr8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs0 TOLL-LIKE RECEPTOR 3

(Homo sapiens) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 466
LEU A 469
SER A 464
LEU A 485
 None
 1.39A 5kb5A-5gs0A:
undetectable		 5kb5A-5gs0A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzp TRIOSEPHOSPHATE
ISOMERASE

(Plasmodium
falciparum) 		PF00121
(TIM) 		4 ASN A 119
LEU A 121
SER A  79
LEU A  86
 None
 1.20A 5kb5A-5gzpA:
undetectable		 5kb5A-5gzpA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxt (2Z,6Z)-FARNESYL
DIPHOSPHATE
SYNTHASE,
CHLOROPLASTIC

(Solanum
habrochaites) 		PF01255
(Prenyltransf) 		4 ASN A 200
LEU A 199
SER A 131
LEU A 145
 None
None
IPR  A 403 (-2.9A)
None
 1.02A 5kb5A-5hxtA:
undetectable		 5kb5A-5hxtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijg CYS/MET METABOLISM
PYRIDOXAL-PHOSPHATE-
DEPENDENT ENZYME

(Brucella
melitensis) 		PF01053
(Cys_Met_Meta_PP) 		4 ASN A 185
LEU A 219
SER A 189
LEU A 320
 None
 1.16A 5kb5A-5ijgA:
undetectable		 5kb5A-5ijgA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus) 		PF05729
(NACHT)
PF13516
(LRR_6) 		4 ASN A 945
LEU A 947
SER A 971
LEU A 968
 None
 1.26A 5kb5A-5irmA:
undetectable		 5kb5A-5irmA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A

(Rattus
norvegicus) 		no annotation 4 ASN A 174
LEU A 173
SER A 171
LEU A 131
 None
None
NAG  A 301 (-3.1A)
NAG  A 301 (-3.8A)
 1.35A 5kb5A-5j2sA:
undetectable		 5kb5A-5j2sA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkq PFVFT1

(Plasmodium
falciparum) 		no annotation 4 ASN A 220
LEU A 223
SER A 218
LEU A 213
 None
 1.13A 5kb5A-5jkqA:
undetectable		 5kb5A-5jkqA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kh1 INVASION PLASMID
ANTIGEN

(Shigella
flexneri) 		PF12468
(TTSSLRR)
PF14496
(NEL) 		4 ASN A 252
LEU A 254
SER A 250
LEU A 262
 None
 1.39A 5kb5A-5kh1A:
undetectable		 5kb5A-5kh1A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzs PUTATIVE CELL
SURFACE PROTEIN,
SIMILAR TO
INTERNALIN PROTEINS

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 ASN A 207
LEU A 209
SER A 227
LEU A 224
 None
 1.17A 5kb5A-5kzsA:
undetectable		 5kb5A-5kzsA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wy3 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 ASN A 261
LEU A 257
SER A 259
LEU A 240
 None
 1.32A 5kb5A-5wy3A:
undetectable		 5kb5A-5wy3A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfo PHD FINGER PROTEIN 1

(Homo sapiens) 		PF00628
(PHD) 		4 ASN A 284
LEU A 288
SER A 282
LEU A 305
 None
 1.21A 5kb5A-5xfoA:
undetectable		 5kb5A-5xfoA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xrf SNAKE VENOM SERINE
PROTEASE DA-36

(Deinagkistrodon
acutus) 		no annotation 4 ASN A 169
LEU A 171
SER A 142
LEU A 190
 None
 1.16A 5kb5A-5xrfA:
undetectable		 5kb5A-5xrfA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 ASN A 318
LEU A 320
SER A 342
LEU A 339
 None
 1.26A 5kb5A-5y3jA:
undetectable		 5kb5A-5y3jA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 ASN A 531
LEU A 533
SER A 553
LEU A 550
 None
 1.14A 5kb5A-5y3jA:
undetectable		 5kb5A-5y3jA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 ASN A 318
LEU A 320
SER A 342
LEU A 339
 None
 1.27A 5kb5A-5zlnA:
undetectable		 5kb5A-5zlnA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 ASN A 532
LEU A 534
SER A 554
LEU A 551
 None
 1.16A 5kb5A-5zlnA:
undetectable		 5kb5A-5zlnA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 ASN A 688
LEU A 690
SER A 710
LEU A 707
 None
None
NAG  A 914 (-3.4A)
None
 1.28A 5kb5A-5zlnA:
undetectable		 5kb5A-5zlnA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bv2 AMINOPEPTIDASE N

(Sus scrofa) 		no annotation 4 ASN A 866
LEU A 838
SER A 862
LEU A 829
 None
 1.27A 5kb5A-6bv2A:
undetectable		 5kb5A-6bv2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6y APRA
METHYLTRANSFERASE 2

(Moorea
bouillonii) 		no annotation 4 ASN A 931
LEU A 930
SER A 903
LEU A 834
 None
 1.37A 5kb5A-6d6yA:
4.0		 5kb5A-6d6yA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 4 ASN A 576
LEU A 586
SER A 601
LEU A 566
 None
 1.14A 5kb5A-6eojA:
undetectable		 5kb5A-6eojA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARC

(Acetobacterium
woodii) 		no annotation 4 ASN C  90
LEU C  86
SER C  88
LEU C  41
 None
 0.97A 5kb5A-6fahC:
undetectable		 5kb5A-6fahC:
13.49