SIMILAR PATTERNS OF AMINO ACIDS FOR 5K50_A_ACTA1403_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b4t PROTEIN (CU/ZN
SUPEROXIDE
DISMUTASE)

(Saccharomyces
cerevisiae) 		PF00080
(Sod_Cu) 		4 SER A  14
VAL A  13
GLY A  36
ALA A  35
 None
 1.08A 5k50A-1b4tA:
0.0		 5k50A-1b4tA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		4 SER A 326
VAL A 325
GLY A  27
ALA A  26
 None
 0.94A 5k50A-1e0tA:
0.6		 5k50A-1e0tA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fy1 HEPARIN-BINDING
PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A  17
VAL A  54
GLY A  56
ALA A  57
 None
None
EOH  A 300 (-4.8A)
None
 1.08A 5k50A-1fy1A:
0.0		 5k50A-1fy1A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gv3 MANGANESE SUPEROXIDE
DISMUTASE

(Nostoc sp. PCC
7120) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 SER A 181
VAL A 167
GLY A 158
ALA A 157
 None
 0.97A 5k50A-1gv3A:
0.0		 5k50A-1gv3A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h8b ALPHA-ACTININ 2,
SKELETAL MUSCLE
ISOFORM

(Homo sapiens) 		PF08726
(EFhand_Ca_insen) 		4 SER A  53
VAL A  54
GLY A  56
ALA A  57
 None
 0.90A 5k50A-1h8bA:
undetectable		 5k50A-1h8bA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjq SIROHEME SYNTHASE

(Salmonella
enterica) 		PF00590
(TP_methylase)
PF10414
(CysG_dimeriser)
PF13241
(NAD_binding_7)
PF14824
(Sirohm_synth_M) 		4 SER A 252
VAL A 251
GLY A 301
ALA A 223
 None
 1.03A 5k50A-1pjqA:
7.5		 5k50A-1pjqA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrd INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Thermotoga
maritima) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 SER A  80
VAL A  79
GLY A 237
ALA A 236
 None
 0.96A 5k50A-1vrdA:
2.3		 5k50A-1vrdA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wba WINGED BEAN ALBUMIN
1

(Psophocarpus
tetragonolobus) 		PF00197
(Kunitz_legume) 		4 SER A  23
VAL A  22
GLY A  29
ALA A  28
 None
 0.83A 5k50A-1wbaA:
0.0		 5k50A-1wbaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1znx GUANYLATE KINASE

(Mycobacterium
tuberculosis) 		PF00625
(Guanylate_kin) 		4 SER A  27
VAL A 120
GLY A 124
ALA A 125
 None
None
5GP  A 300 ( 4.9A)
None
 1.09A 5k50A-1znxA:
2.1		 5k50A-1znxA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ae6 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF00583
(Acetyltransf_1) 		4 SER A  87
VAL A  86
GLY A  63
ALA A  62
 None
 1.00A 5k50A-2ae6A:
0.0		 5k50A-2ae6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aka DYNAMIN-1

(Rattus
norvegicus) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 SER B 175
VAL B 174
GLY B  38
ALA B 186
 None
 1.06A 5k50A-2akaB:
undetectable		 5k50A-2akaB:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bb6 TRANSCOBALAMIN II

(Bos taurus) 		PF01122
(Cobalamin_bind) 		4 SER A 177
VAL A 178
GLY A 226
ALA A 218
 None
 0.90A 5k50A-2bb6A:
undetectable		 5k50A-2bb6A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mns MEMBRANE FUSION
PROTEIN P15

(Baboon
orthoreovirus) 		no annotation 4 SER A  12
VAL A  10
GLY A   7
ALA A   8
 None
 1.04A 5k50A-2mnsA:
undetectable		 5k50A-2mnsA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n8y ALPHA-ACTININ-1

(Homo sapiens) 		PF00036
(EF-hand_1)
PF08726
(EFhand_Ca_insen) 		4 SER A 872
VAL A 873
GLY A 875
ALA A 876
 None
 0.87A 5k50A-2n8yA:
undetectable		 5k50A-2n8yA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nx9 OXALOACETATE
DECARBOXYLASE 2,
SUBUNIT ALPHA

(Vibrio cholerae) 		PF00682
(HMGL-like)
PF02436
(PYC_OADA) 		4 SER A 194
VAL A 193
GLY A 226
ALA A 225
 None
 0.94A 5k50A-2nx9A:
undetectable		 5k50A-2nx9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1x 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE

(Deinococcus
radiodurans) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
PF13292
(DXP_synthase_N) 		4 SER A 602
VAL A 603
GLY A 428
ALA A 598
 None
 1.03A 5k50A-2o1xA:
2.8		 5k50A-2o1xA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5

(Mus musculus) 		PF00400
(WD40) 		4 SER B 256
VAL B 245
GLY B 215
ALA B 221
 None
 0.59A 5k50A-2pbiB:
undetectable		 5k50A-2pbiB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5

(Mus musculus) 		PF00400
(WD40) 		4 SER B 288
VAL B 289
GLY B 257
ALA B 286
 None
 1.08A 5k50A-2pbiB:
undetectable		 5k50A-2pbiB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pce PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Roseovarius
nubinhibens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 SER A 273
VAL A 272
GLY A 277
ALA A 103
 None
 1.09A 5k50A-2pceA:
undetectable		 5k50A-2pceA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prz OROTATE
PHOSPHORIBOSYLTRANSF
ERASE 1

(Saccharomyces
cerevisiae) 		PF00156
(Pribosyltran) 		4 SER A 176
VAL A 166
GLY A 222
ALA A 223
 None
 0.94A 5k50A-2przA:
undetectable		 5k50A-2przA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE

(Azospirillum
brasilense) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 SER A  97
VAL A  70
GLY A  75
ALA A  76
 None
 0.90A 5k50A-2q5oA:
undetectable		 5k50A-2q5oA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vbi PYRUVATE
DECARBOXYLASE

(Acetobacter
pasteurianus) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 SER A  98
VAL A  71
GLY A  76
ALA A  77
 None
 0.93A 5k50A-2vbiA:
undetectable		 5k50A-2vbiA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjv REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF09416
(UPF1_Zn_bind)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 SER A 438
VAL A 437
GLY A 653
ALA A 654
 None
 0.98A 5k50A-2wjvA:
2.6		 5k50A-2wjvA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wvg PYRUVATE
DECARBOXYLASE

(Zymomonas
mobilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 SER A  98
VAL A  71
GLY A  76
ALA A  77
 None
 0.91A 5k50A-2wvgA:
undetectable		 5k50A-2wvgA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 SER A 438
VAL A 437
GLY A 653
ALA A 654
 None
 1.02A 5k50A-2xzoA:
2.4		 5k50A-2xzoA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeh HEMOGLOBIN-BINDING
PROTEASE HBP
AUTOTRANSPORTER

(Escherichia
coli) 		PF03797
(Autotransporter) 		4 SER A1287
VAL A1286
GLY A1303
ALA A1302
 None
 0.95A 5k50A-3aehA:
undetectable		 5k50A-3aehA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bba INTERPAIN A

(Prevotella
intermedia) 		PF01640
(Peptidase_C10) 		4 SER A 295
VAL A 294
GLY A 304
ALA A 303
 None
 0.95A 5k50A-3bbaA:
undetectable		 5k50A-3bbaA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgw DNAB-LIKE
REPLICATIVE HELICASE

(Bacillus phage
SPP1) 		PF00772
(DnaB)
PF03796
(DnaB_C) 		4 SER A  90
VAL A  91
GLY A  21
ALA A  18
 None
 1.06A 5k50A-3bgwA:
undetectable		 5k50A-3bgwA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6k PUTATIVE
AMINOTRANSFERASE

(Corynebacterium
diphtheriae) 		PF12897
(Aminotran_MocR) 		4 SER A 358
VAL A 361
GLY A 373
ALA A 374
 None
 1.06A 5k50A-3d6kA:
undetectable		 5k50A-3d6kA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3feg CHOLINE/ETHANOLAMINE
KINASE

(Homo sapiens) 		PF01633
(Choline_kinase) 		4 SER A  93
VAL A  94
GLY A  59
ALA A  60
 None
 0.84A 5k50A-3fegA:
undetectable		 5k50A-3fegA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpv EXTRACELLULAR
HAEM-BINDING PROTEIN

(Streptomyces
reticuli) 		PF03928
(Haem_degrading) 		4 SER A  53
VAL A  52
GLY A 136
ALA A 135
 None
None
FE  A 157 ( 4.4A)
FE  A 157 (-3.6A)
 1.02A 5k50A-3fpvA:
undetectable		 5k50A-3fpvA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2b SAM-DEPENDENT
METHYLTRANSFERASE

(Corynebacterium
glutamicum) 		PF13649
(Methyltransf_25) 		4 SER A 142
VAL A 143
GLY A 114
ALA A 117
 None
 0.94A 5k50A-3h2bA:
5.9		 5k50A-3h2bA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdi PROCESSING PROTEASE

(Bacillus
halodurans) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 SER A  25
VAL A  24
GLY A 190
ALA A 189
 None
 1.08A 5k50A-3hdiA:
undetectable		 5k50A-3hdiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr2 HEXULOSE-6-PHOSPHATE
SYNTHASE SGBH

(Vibrio cholerae) 		PF00215
(OMPdecase) 		4 SER A  48
VAL A  47
GLY A  80
ALA A  79
 None
 0.91A 5k50A-3jr2A:
undetectable		 5k50A-3jr2A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kly PUTATIVE FORMATE
TRANSPORTER 1

(Vibrio cholerae) 		PF01226
(Form_Nir_trans) 		4 SER A 203
VAL A 202
GLY A  71
ALA A 199
 None
 1.07A 5k50A-3klyA:
undetectable		 5k50A-3klyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nap CAPSID PROTEIN

(Triatoma virus) 		PF08762
(CRPV_capsid) 		4 SER A 187
VAL A 186
GLY A 107
ALA A 108
 None
 1.04A 5k50A-3napA:
undetectable		 5k50A-3napA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ndo DEOXYRIBOSE-PHOSPHAT
E ALDOLASE

(Mycolicibacterium
smegmatis) 		PF01791
(DeoC) 		4 SER A  50
VAL A  49
GLY A  89
ALA A  88
 None
 0.78A 5k50A-3ndoA:
2.7		 5k50A-3ndoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvl 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Trypanosoma
brucei) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 SER A 197
VAL A 257
GLY A 228
ALA A 222
 None
 1.08A 5k50A-3nvlA:
4.2		 5k50A-3nvlA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oa3 ALDOLASE

(Coccidioides
immitis) 		PF01791
(DeoC) 		4 SER A 201
VAL A 200
GLY A 235
ALA A 234
 None
 1.05A 5k50A-3oa3A:
undetectable		 5k50A-3oa3A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oev PROTEASOME COMPONENT
Y13

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		4 SER B 135
VAL B 134
GLY B  80
ALA B  79
 None
 1.01A 5k50A-3oevB:
undetectable		 5k50A-3oevB:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster) 		PF00291
(PALP)
PF00571
(CBS) 		4 SER A 223
VAL A 249
GLY A 321
ALA A 322
 P1T  A 702 ( 3.7A)
None
None
None
 1.08A 5k50A-3pc3A:
undetectable		 5k50A-3pc3A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr2 TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Salmonella
enterica) 		PF00290
(Trp_syntA) 		4 SER A 260
VAL A 259
GLY A  44
ALA A  43
 None
 1.06A 5k50A-3pr2A:
undetectable		 5k50A-3pr2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qz1 STEROID
21-HYDROXYLASE

(Bos taurus) 		PF00067
(p450) 		4 MET A 282
SER A 283
VAL A 280
GLY A 278
 None
 1.09A 5k50A-3qz1A:
undetectable		 5k50A-3qz1A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7k PROBABLE ACYL COA
DEHYDROGENASE

(Mycobacteroides
abscessus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 MET A 308
VAL A 312
GLY A 275
ALA A 274
 None
 1.05A 5k50A-3r7kA:
undetectable		 5k50A-3r7kA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 SER A 279
VAL A 278
GLY A 306
ALA A 275
 None
 1.02A 5k50A-3sghA:
undetectable		 5k50A-3sghA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vqr PUTATIVE
OXIDOREDUCTASE

(Aeropyrum
pernix) 		PF01266
(DAO) 		4 SER A  86
VAL A  84
GLY A 277
ALA A 278
 None
 1.02A 5k50A-3vqrA:
3.9		 5k50A-3vqrA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wry TM-1 PROTEIN

(Solanum
lycopersicum) 		PF06792
(UPF0261) 		4 SER A 371
VAL A 370
GLY A 304
ALA A 305
 None
 0.96A 5k50A-3wryA:
4.0		 5k50A-3wryA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zl8 UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE

(Thermotoga
maritima) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 SER A 407
VAL A 410
GLY A 335
ALA A 336
 None
 1.02A 5k50A-3zl8A:
6.7		 5k50A-3zl8A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxl HIAXHD3

(Humicola
insolens) 		PF04616
(Glyco_hydro_43) 		4 SER A  83
VAL A  84
GLY A  65
ALA A  66
 None
 0.90A 5k50A-3zxlA:
undetectable		 5k50A-3zxlA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmr RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA

(Bacillus cereus) 		PF00268
(Ribonuc_red_sm) 		4 MET A 154
SER A 157
VAL A 158
GLY A 203
 None
 0.98A 5k50A-4bmrA:
undetectable		 5k50A-4bmrA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmw EXTRACELLULAR
HAEM-BINDING PROTEIN

(Streptomyces
reticuli) 		PF03928
(Haem_degrading) 		4 SER A  53
VAL A  52
GLY A 136
ALA A 135
 None
 1.02A 5k50A-4bmwA:
undetectable		 5k50A-4bmwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c4a PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Mus musculus) 		PF06325
(PrmA) 		4 SER A  57
VAL A  56
GLY A  86
ALA A  85
 None
 0.91A 5k50A-4c4aA:
2.8		 5k50A-4c4aA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cok PYRUVATE
DECARBOXYLASE

(Gluconacetobacter
diazotrophicus) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 SER A  98
VAL A  71
GLY A  76
ALA A  77
 None
 0.94A 5k50A-4cokA:
undetectable		 5k50A-4cokA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr2 26S PROTEASE
REGULATORY SUBUNIT 4
HOMOLOG

(Saccharomyces
cerevisiae) 		PF00004
(AAA) 		4 SER I 277
VAL I 322
GLY I 272
ALA I 271
 None
 0.89A 5k50A-4cr2I:
undetectable		 5k50A-4cr2I:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dal PUTATIVE ALDEHYDE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 SER A 385
VAL A 365
GLY A 367
ALA A 368
 None
 0.98A 5k50A-4dalA:
4.5		 5k50A-4dalA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dr0 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA

(Bacillus
subtilis) 		PF00268
(Ribonuc_red_sm) 		4 MET A 157
SER A 160
VAL A 161
GLY A 206
 None
 0.92A 5k50A-4dr0A:
undetectable		 5k50A-4dr0A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g10 GLUTATHIONE
S-TRANSFERASE
HOMOLOG

(Sphingomonas
paucimobilis) 		PF13417
(GST_N_3)
PF16865
(GST_C_5) 		4 MET A 127
VAL A 131
GLY A 112
ALA A 111
 None
 1.00A 5k50A-4g10A:
undetectable		 5k50A-4g10A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6x GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Catenulispora
acidiphila) 		PF00903
(Glyoxalase) 		4 SER A  44
VAL A  43
GLY A  50
ALA A  47
 None
 1.00A 5k50A-4g6xA:
undetectable		 5k50A-4g6xA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jn6 4-HYDROXY-2-OXOVALER
ATE ALDOLASE

(Mycobacterium
tuberculosis) 		PF00682
(HMGL-like)
PF07836
(DmpG_comm) 		4 SER A 183
VAL A 182
GLY A 217
ALA A 216
 None
 0.94A 5k50A-4jn6A:
undetectable		 5k50A-4jn6A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kc5 RHIE PROTEIN

(Paraburkholderia
rhizoxinica) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 SER A3820
VAL A3819
GLY A3838
ALA A3816
 None
 1.08A 5k50A-4kc5A:
undetectable		 5k50A-4kc5A:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigenium
vulgare) 		PF13360
(PQQ_2) 		4 SER A 178
VAL A 177
GLY A 165
ALA A 164
 None
 0.93A 5k50A-4mh1A:
undetectable		 5k50A-4mh1A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtk VGRG1

(Pseudomonas
aeruginosa) 		PF05954
(Phage_GPD) 		4 SER A  41
VAL A  40
GLY A  88
ALA A  87
 None
 1.00A 5k50A-4mtkA:
undetectable		 5k50A-4mtkA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnb OBCA, OXALATE
BIOSYNTHETIC
COMPONENT A

(Burkholderia
glumae) 		PF05853
(BKACE) 		4 SER A 498
VAL A 497
GLY A 217
ALA A 216
 None
 0.84A 5k50A-4nnbA:
2.6		 5k50A-4nnbA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		4 MET A 418
SER A 417
GLY A 350
ALA A 347
 None
 1.00A 5k50A-4q0gA:
3.6		 5k50A-4q0gA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r40 PROTEIN TOLB

(Yersinia pestis) 		PF04052
(TolB_N)
PF07676
(PD40) 		4 MET A 203
SER A 204
GLY A 247
ALA A 248
 None
 0.87A 5k50A-4r40A:
2.7		 5k50A-4r40A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqv ALGM2

(Sphingomonas
sp.) 		PF00528
(BPD_transp_1) 		4 MET B  39
SER B  42
GLY B  44
ALA B  46
 None
 1.05A 5k50A-4tqvB:
undetectable		 5k50A-4tqvB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x0e PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		4 SER A 133
VAL A 132
GLY A 107
ALA A 108
 None
 1.02A 5k50A-4x0eA:
3.8		 5k50A-4x0eA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9w ASPARTIC ACID
ENDOPEPTIDASE SAPP2

(Candida
parapsilosis) 		PF00026
(Asp) 		4 SER A 184
VAL A 183
GLY A 207
ALA A 189
 None
 1.00A 5k50A-4y9wA:
undetectable		 5k50A-4y9wA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		4 SER A 133
VAL A 132
GLY A 107
ALA A 108
 None
NAP  A 301 (-4.8A)
NAP  A 301 (-3.1A)
None
 0.85A 5k50A-4ybrA:
3.7		 5k50A-4ybrA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II) 		4 SER A 214
VAL A 215
GLY A 178
ALA A 175
 None
 0.92A 5k50A-5b47A:
undetectable		 5k50A-5b47A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d3q DYNAMIN-1,DYNAMIN-1

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 SER A 175
VAL A 174
GLY A  38
ALA A 186
 None
 1.03A 5k50A-5d3qA:
undetectable		 5k50A-5d3qA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5n MONOOXYGENASE

(Micromonospora
sp. TP-A0468) 		PF05368
(NmrA) 		4 SER A 113
VAL A 114
GLY A 116
ALA A 117
 None
NAD  A 301 ( 4.6A)
None
None
 0.96A 5k50A-5f5nA:
15.5		 5k50A-5f5nA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f84 O-GLUCOSYLTRANSFERAS
E RUMI

(Drosophila
melanogaster) 		PF05686
(Glyco_transf_90) 		4 MET A  96
SER A  99
GLY A 164
ALA A 162
 None
 1.08A 5k50A-5f84A:
undetectable		 5k50A-5f84A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hx0 UNCHARACTERIZED
PROTEIN DFER_1899

(Dyadobacter
fermentans) 		PF13088
(BNR_2) 		4 SER A 259
VAL A 258
GLY A 281
ALA A 280
 None
 1.07A 5k50A-5hx0A:
undetectable		 5k50A-5hx0A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijg CYS/MET METABOLISM
PYRIDOXAL-PHOSPHATE-
DEPENDENT ENZYME

(Brucella
melitensis) 		PF01053
(Cys_Met_Meta_PP) 		4 SER A 259
VAL A 260
GLY A 256
ALA A 257
 None
 1.08A 5k50A-5ijgA:
undetectable		 5k50A-5ijgA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkq PFVFT1

(Plasmodium
falciparum) 		no annotation 4 SER A 260
VAL A 261
GLY A 269
ALA A 226
 None
 1.05A 5k50A-5jkqA:
undetectable		 5k50A-5jkqA:
21.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5k50 L-THREONINE
3-DEHYDROGENASE

(Trypanosoma
brucei) 		no annotation 5 MET A1081
SER A1082
VAL A1083
GLY A1184
ALA A1185
 NAD  A1401 (-3.7A)
ACT  A1403 (-4.3A)
ACT  A1403 (-3.9A)
ACT  A1403 (-3.4A)
ACT  A1403 (-3.3A)
 0.02A 5k50A-5k50A:
58.0		 5k50A-5k50A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwn E3 UBIQUITIN-PROTEIN
LIGASE COP1

(Arabidopsis
thaliana) 		PF00400
(WD40) 		4 SER A 376
VAL A 374
GLY A 390
ALA A 389
 None
 1.06A 5k50A-5kwnA:
undetectable		 5k50A-5kwnA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kxj L-ASPARTATE OXIDASE

(Salmonella
enterica) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 SER A 199
VAL A 200
GLY A 181
ALA A 197
 None
 1.07A 5k50A-5kxjA:
undetectable		 5k50A-5kxjA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4

(Bos taurus) 		PF00361
(Proton_antipo_M)
PF01059
(Oxidored_q5_N) 		4 SER M 308
VAL M 381
GLY M 311
ALA M 312
 None
 1.07A 5k50A-5lc5M:
undetectable		 5k50A-5lc5M:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcx (-)-ISOPIPERITENONE
REDUCTASE

(Mentha x
piperita) 		PF00106
(adh_short) 		4 SER A 106
VAL A 107
GLY A 138
ALA A 136
 None
 0.81A 5k50A-5lcxA:
16.2		 5k50A-5lcxA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mfb YIII(DQ)4CQI

(synthetic
construct) 		PF00514
(Arm) 		4 SER A  56
VAL A  59
GLY A  95
ALA A  94
 None
 1.06A 5k50A-5mfbA:
undetectable		 5k50A-5mfbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mfb YIII(DQ)4CQI

(synthetic
construct) 		PF00514
(Arm) 		4 SER A 140
VAL A 143
GLY A 179
ALA A 178
 None
 1.04A 5k50A-5mfbA:
undetectable		 5k50A-5mfbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT

(Escherichia
coli) 		PF03814
(KdpA) 		4 SER A 461
VAL A 460
GLY A 431
ALA A 432
 None
 1.00A 5k50A-5mrwA:
undetectable		 5k50A-5mrwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msc CARBOXYLIC ACID
REDUCTASE

(Nocardia
iowensis) 		PF00501
(AMP-binding) 		4 SER A 362
VAL A 363
GLY A 365
ALA A 366
 None
 1.03A 5k50A-5mscA:
3.9		 5k50A-5mscA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbs BETA-GLUCOSIDASE

(Neurospora
crassa) 		no annotation 4 SER A 639
VAL A 640
GLY A 597
ALA A 598
 None
 1.04A 5k50A-5nbsA:
undetectable		 5k50A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npu ANC27

(synthetic
construct) 		no annotation 4 SER A  98
VAL A  71
GLY A  76
ALA A  77
 None
 0.95A 5k50A-5npuA:
undetectable		 5k50A-5npuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis) 		no annotation 4 MET A 467
SER A 468
VAL A 469
GLY A 420
 None
 1.02A 5k50A-5nvaA:
undetectable		 5k50A-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t7d PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE

(Streptomyces
hygroscopicus) 		PF13420
(Acetyltransf_4) 		4 SER A  94
VAL A  93
GLY A  70
ALA A  69
 None
ACO  A 800 (-3.9A)
None
None
 0.90A 5k50A-5t7dA:
undetectable		 5k50A-5t7dA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td7 ZGC:55652

(Danio rerio) 		PF00850
(Hist_deacetyl) 		4 SER A 118
VAL A 119
GLY A 127
ALA A   6
 None
 1.06A 5k50A-5td7A:
5.8		 5k50A-5td7A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A 191
VAL A 190
GLY A 252
ALA A 251
 None
 0.75A 5k50A-5tf0A:
undetectable		 5k50A-5tf0A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr PROTEASOME SUBUNIT
ALPHA TYPE-4

(Homo sapiens) 		no annotation 4 SER I 133
VAL I 132
GLY I  78
ALA I  77
 None
 0.96A 5k50A-5vfrI:
undetectable		 5k50A-5vfrI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjg VACUOLAR PROTEIN 8

(Saccharomyces
cerevisiae) 		PF00514
(Arm) 		4 SER A 254
VAL A 257
GLY A 292
ALA A 291
 None
None
PE5  A 601 (-3.9A)
None
 0.99A 5k50A-5xjgA:
undetectable		 5k50A-5xjgA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
PERMEAE

(Streptococcus
pneumoniae) 		no annotation 4 SER M  31
VAL M  32
GLY M 297
ALA M 296
 None
 1.05A 5k50A-5xu1M:
undetectable		 5k50A-5xu1M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxh PARTICULATE METHANE
MONOOXYGENASE, A
SUBUNIT

(Methylomicrobium
alcaliphilum) 		no annotation 4 SER B  68
VAL B  67
GLY B  45
ALA B  64
 None
 0.96A 5k50A-6cxhB:
undetectable		 5k50A-6cxhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoq DIPEPTIDYL PEPTIDASE
9

(Homo sapiens) 		no annotation 4 SER A 531
VAL A 530
GLY A 536
ALA A 535
 None
 1.02A 5k50A-6eoqA:
undetectable		 5k50A-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f34 AMINO ACID
TRANSPORTER

(Geobacillus
kaustophilus) 		no annotation 4 MET A 322
SER A 321
GLY A 117
ALA A 119
 None
ARG  A 501 (-3.4A)
None
ARG  A 501 (-3.3A)
 0.93A 5k50A-6f34A:
undetectable		 5k50A-6f34A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhw GLUCOAMYLASE P

(Amorphotheca
resinae) 		no annotation 4 SER A 508
VAL A 507
GLY A 597
ALA A 599
 None
 1.01A 5k50A-6fhwA:
undetectable		 5k50A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae) 		no annotation 4 SER A 741
VAL A 740
GLY A 579
ALA A 737
 None
 1.02A 5k50A-6fikA:
undetectable		 5k50A-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL

(Mus musculus) 		no annotation 4 SER B 125
VAL B  98
GLY B 100
ALA B 130
 None
None
SF4  B 201 ( 3.7A)
None
 1.02A 5k50A-6g72B:
undetectable		 5k50A-6g72B:
undetectable