SIMILAR PATTERNS OF AMINO ACIDS FOR 5K4P_A_SORA611_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cdo | ALCOHOLDEHYDROGENASE (Gadus morhua) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 320THR A 179SER A 178GLY A 176 | NoneNAD A 375 (-3.1A)NoneNone | 0.90A | 5k4pA-1cdoA:0.0 | 5k4pA-1cdoA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1csj | HEPATITIS C VIRUSRNA POLYMERASE(NS5B) (Hepacivirus C) |
PF00998(RdRP_3) | 4 | GLY A 275THR A 7GLY A 8ASN A 273 | None | 0.87A | 5k4pA-1csjA:undetectable | 5k4pA-1csjA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d1t | ALCOHOLDEHYDROGENASE CLASSIV SIGMA CHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 320THR A 178SER A 177GLY A 175 | NoneNAD A1377 (-2.8A)NoneNAD A1377 ( 4.8A) | 0.82A | 5k4pA-1d1tA:undetectable | 5k4pA-1d1tA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dpp | DIPEPTIDE BINDINGPROTEIN (Escherichiacoli) |
PF00496(SBP_bac_5) | 4 | GLY A 183THR A 182TYR A 204ASN A 34 | None | 0.69A | 5k4pA-1dppA:0.0 | 5k4pA-1dppA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ee2 | ALCOHOLDEHYDROGENASE (Equus caballus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 319THR A 177SER A 176GLY A 174 | NoneNAD A1100 (-3.3A)NoneNone | 0.90A | 5k4pA-1ee2A:0.0 | 5k4pA-1ee2A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f5j | BETA-1,4-XYLANASE (Dictyoglomusthermophilum) |
PF00457(Glyco_hydro_11) | 4 | GLY A 49THR A 48TYR A 13ASN A 193 | None | 0.92A | 5k4pA-1f5jA:undetectable | 5k4pA-1f5jA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fno | PEPTIDASE T (Salmonellaenterica) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | GLY A 355THR A 356TYR A 319GLY A 358ASN A 207 | SO4 A 600 (-4.1A)NoneSO4 A 600 (-4.8A)NoneNone | 1.33A | 5k4pA-1fnoA:0.5 | 5k4pA-1fnoA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g01 | ENDOGLUCANASE (Bacillus sp.KSM-635) |
PF00150(Cellulase)PF03424(CBM_17_28) | 4 | GLY A 487THR A 488SER A 489ASN A 518 | None | 0.80A | 5k4pA-1g01A:1.6 | 5k4pA-1g01A:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gl9 | REVERSE GYRASE (Archaeoglobusfulgidus) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 4 | GLY B 434THR B 436SER B 437GLY B 447 | None | 0.73A | 5k4pA-1gl9B:0.0 | 5k4pA-1gl9B:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i77 | CYTOCHROME C3 (Desulfovibriodesulfuricans) |
PF02085(Cytochrom_CIII) | 4 | GLY A 60SER A 63TYR A 66GLY A 57 | None | 0.86A | 5k4pA-1i77A:undetectable | 5k4pA-1i77A:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mac | 1,3-1,4-BETA-D-GLUCAN 4-GLUCANOHYDROLASE (Paenibacillusmacerans) |
PF00722(Glyco_hydro_16) | 4 | THR A 83TYR A 194GLY A 192ASN A 195 | None | 0.89A | 5k4pA-1macA:undetectable | 5k4pA-1macA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mec | MENGO VIRUS COATPROTEIN (SUBUNITVP1) (Cardiovirus A) |
no annotation | 4 | GLY 1 149THR 1 148GLY 1 223ASN 1 219 | None | 0.89A | 5k4pA-1mec1:undetectable | 5k4pA-1mec1:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nlr | ENDO-1,4-BETA-GLUCANASE (Streptomyceslividans) |
PF01670(Glyco_hydro_12) | 4 | GLY A 92SER A 170GLY A 171ASN A 214 | None | 0.92A | 5k4pA-1nlrA:undetectable | 5k4pA-1nlrA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvh | LEUKEMIA INHIBITORYFACTOR (Homo sapiens) |
PF01291(LIF_OSM) | 4 | GLY B 91THR B 92SER B 93GLY B 147 | None | 0.82A | 5k4pA-1pvhB:undetectable | 5k4pA-1pvhB:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rjc | CAMELID HEAVY CHAINANTIBODY (Camelusdromedarius) |
PF07686(V-set) | 4 | GLY A 109THR A 110TYR A 114GLY A 47 | None | 0.69A | 5k4pA-1rjcA:undetectable | 5k4pA-1rjcA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rk2 | RIBOKINASE (Escherichiacoli) |
PF00294(PfkB) | 5 | GLY A 96THR A 95SER A 94GLY A 65ASN A 117 | None | 1.18A | 5k4pA-1rk2A:undetectable | 5k4pA-1rk2A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u3t | ALCOHOLDEHYDROGENASE ALPHACHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 320THR A 178SER A 177GLY A 175 | NoneNAD A1377 (-3.0A)NoneNone | 0.85A | 5k4pA-1u3tA:undetectable | 5k4pA-1u3tA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wji | TUDOR DOMAINCONTAINING PROTEIN 3 (Homo sapiens) |
PF00627(UBA) | 4 | GLY A 7SER A 5GLY A 1ASN A 35 | None | 0.77A | 5k4pA-1wjiA:undetectable | 5k4pA-1wjiA:14.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yfz | HYPOXANTHINE-GUANINEPHOSPHORIBOSYLTRANSFERASE (Caldanaerobactersubterraneus) |
PF00156(Pribosyltran) | 4 | GLY A 80THR A 76SER A 75GLY A 73 | None | 0.85A | 5k4pA-1yfzA:undetectable | 5k4pA-1yfzA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yub | RRNAMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF00398(RrnaAD) | 4 | GLY A 37THR A 38GLY A 39ASN A 100 | None | 0.90A | 5k4pA-1yubA:undetectable | 5k4pA-1yubA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aa4 | PUTATIVEN-ACETYLMANNOSAMINEKINASE (Escherichiacoli) |
PF00480(ROK) | 4 | GLY A 9THR A 64SER A 63GLY A 65 | None | 0.87A | 5k4pA-2aa4A:undetectable | 5k4pA-2aa4A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2azp | HYPOTHETICAL PROTEINPA1268 (Pseudomonasaeruginosa) |
PF05544(Pro_racemase) | 4 | GLY A 160THR A 238SER A 241GLY A 237 | None | 0.87A | 5k4pA-2azpA:undetectable | 5k4pA-2azpA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bq8 | TARTRATE-RESISTANTACID PHOSPHATASETYPE 5 (Homo sapiens) |
PF00149(Metallophos) | 4 | GLY X 270SER X 237GLY X 11ASN X 29 | None | 0.67A | 5k4pA-2bq8X:undetectable | 5k4pA-2bq8X:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fzw | ALCOHOLDEHYDROGENASE CLASSIII CHI CHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 319THR A 177SER A 176GLY A 174 | NoneNAD A1377 (-3.0A)NoneNAD A1377 ( 4.4A) | 0.79A | 5k4pA-2fzwA:undetectable | 5k4pA-2fzwA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj9 | AUTOINDUCER2-BINDINGPERIPLASMIC PROTEINLUXP (Vibrio harveyi) |
PF13407(Peripla_BP_4) | 4 | GLY A 316THR A 315GLY A 177ASN A 85 | None | 0.80A | 5k4pA-2hj9A:undetectable | 5k4pA-2hj9A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hzk | TRAP-T FAMILYSORBITOL/MANNITOLTRANSPORTER,PERIPLASMIC BINDINGPROTEIN, SMOM (Rhodobactersphaeroides) |
PF03480(DctP) | 4 | GLY A 242SER A 119GLY A 122ASN A 152 | None | 0.79A | 5k4pA-2hzkA:undetectable | 5k4pA-2hzkA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j92 | PICORNAIN 3C (Foot-and-mouthdisease virus) |
PF00548(Peptidase_C3) | 4 | GLY A 161TYR A 162GLY A 164ASN A 121 | None | 0.92A | 5k4pA-2j92A:undetectable | 5k4pA-2j92A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o14 | HYPOTHETICAL PROTEINYXIM (Bacillussubtilis) |
PF13472(Lipase_GDSL_2) | 4 | GLY A 209SER A 207GLY A 169ASN A 241 | None | 0.92A | 5k4pA-2o14A:undetectable | 5k4pA-2o14A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qj6 | TOXIN A (Clostridioidesdifficile) |
PF01473(CW_binding_1) | 4 | GLY A 129THR A 128TYR A 139GLY A 144 | GLY A 129 ( 0.0A)THR A 128 ( 0.8A)TYR A 139 ( 1.3A)GLY A 144 ( 0.0A) | 0.91A | 5k4pA-2qj6A:undetectable | 5k4pA-2qj6A:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rff | PUTATIVENUCLEOTIDYLTRANSFERASE (Sulfolobussolfataricus) |
PF01909(NTP_transf_2) | 4 | GLY A 44SER A 40TYR A 46GLY A 39 | None | 0.81A | 5k4pA-2rffA:undetectable | 5k4pA-2rffA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vca | ALPHA-N-ACETYLGLUCOSAMINIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C)PF05089(NAGLU)PF12971(NAGLU_N)PF12972(NAGLU_C) | 4 | GLY A 376SER A 359TYR A 363ASN A 803 | None | 0.75A | 5k4pA-2vcaA:undetectable | 5k4pA-2vcaA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqp | POLYSIALIC ACIDCAPSULE BIOSYNTHESISPROTEIN SIAC (Neisseriameningitidis) |
PF03102(NeuB)PF08666(SAF) | 4 | GLY A 156SER A 154GLY A 131ASN A 184 | NoneWQP A1350 (-2.5A)WQP A1350 ( 3.8A)WQP A1350 (-3.5A) | 0.87A | 5k4pA-2wqpA:undetectable | 5k4pA-2wqpA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x8p | CHOLINE-BINDINGPROTEIN F (Streptococcuspneumoniae) |
PF01473(CW_binding_1) | 5 | GLY A 213THR A 212TYR A 223GLY A 229ASN A 226 | None | 1.27A | 5k4pA-2x8pA:undetectable | 5k4pA-2x8pA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xyb | LACCASE (Trametescinnabarina) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | GLY A 269THR A 268GLY A 266ASN A 262 | None | 0.92A | 5k4pA-2xybA:undetectable | 5k4pA-2xybA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3h | ENDOGLUCANASE (Salipaludibacillusagaradhaerens) |
PF00150(Cellulase) | 4 | GLY A 230THR A 231SER A 232ASN A 261 | None | 0.88A | 5k4pA-3a3hA:undetectable | 5k4pA-3a3hA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cos | ALCOHOLDEHYDROGENASE 4 (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 326THR A 184SER A 183GLY A 181 | NoneNAD A 400 (-3.0A)NoneNone | 0.80A | 5k4pA-3cosA:undetectable | 5k4pA-3cosA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cp7 | ALKALINE SERINEPROTEASE AL20 (Nesterenkoniaaethiopica) |
PF13365(Trypsin_2) | 4 | GLY A 10SER A 24TYR A 130GLY A 171 | None | 0.73A | 5k4pA-3cp7A:undetectable | 5k4pA-3cp7A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8k | ALPHA-AMYLASE, SUSG (Bacteroidesthetaiotaomicron) |
PF00128(Alpha-amylase) | 4 | GLY A 362SER A 364TYR A 367GLY A 356 | None | 0.70A | 5k4pA-3k8kA:undetectable | 5k4pA-3k8kA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m8u | HEME-BINDING PROTEINA (Glaesserellaparasuis) |
PF00496(SBP_bac_5) | 4 | GLY A 207THR A 206TYR A 228ASN A 58 | None | 0.75A | 5k4pA-3m8uA:undetectable | 5k4pA-3m8uA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq2 | 16S RRNAMETHYLTRANSFERASE (Streptoalloteichustenebrarius) |
PF02390(Methyltransf_4) | 4 | GLY A 130THR A 212SER A 132GLY A 211 | None | 0.91A | 5k4pA-3mq2A:undetectable | 5k4pA-3mq2A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nps | S4 FAB LIGHT CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY C 68THR C 69SER C 70GLY C 25 | None | 0.90A | 5k4pA-3npsC:undetectable | 5k4pA-3npsC:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ohw | PHYCOBILISOME LCMCORE-MEMBRANE LINKERPOLYPEPTIDE (Synechocystissp. PCC 6803) |
no annotation | 4 | THR B 783SER B 784TYR B 787GLY B 780 | None | 0.80A | 5k4pA-3ohwB:undetectable | 5k4pA-3ohwB:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8k | HYDROLASE,CARBON-NITROGENFAMILY (Staphylococcusaureus) |
PF00795(CN_hydrolase) | 5 | GLY A 202THR A 201SER A 200TYR A 209GLY A 211 | None | 1.49A | 5k4pA-3p8kA:undetectable | 5k4pA-3p8kA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3phf | ENVELOPEGLYCOPROTEIN H (Humangammaherpesvirus4) |
no annotation | 4 | GLY A 394THR A 397SER A 398ASN A 442 | None | 0.80A | 5k4pA-3phfA:undetectable | 5k4pA-3phfA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pzu | ENDOGLUCANASE (Bacillussubtilis) |
PF00150(Cellulase) | 4 | GLY A 259THR A 260SER A 261ASN A 290 | None | 0.83A | 5k4pA-3pzuA:undetectable | 5k4pA-3pzuA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qs3 | FIMBRILLIN MATBHOMOLOG, ECPD (Escherichiacoli) |
PF16449(MatB) | 5 | GLY A 140THR A 141SER A 81GLY A 144ASN A 84 | None | 1.36A | 5k4pA-3qs3A:undetectable | 5k4pA-3qs3A:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sfz | APOPTOTIC PEPTIDASEACTIVATING FACTOR 1 (Mus musculus) |
PF00400(WD40)PF00931(NB-ARC)PF12894(ANAPC4_WD40) | 4 | GLY A1198THR A1219TYR A1199GLY A1218 | None | 0.79A | 5k4pA-3sfzA:undetectable | 5k4pA-3sfzA:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tpa | HEME-BINDING PROTEINA (Glaesserellaparasuis) |
PF00496(SBP_bac_5) | 4 | GLY A 190THR A 189TYR A 211ASN A 41 | None | 0.72A | 5k4pA-3tpaA:undetectable | 5k4pA-3tpaA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tzq | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriummarinum) |
no annotation | 4 | GLY B 20THR B 23SER B 24ASN B 88 | None | 0.87A | 5k4pA-3tzqB:undetectable | 5k4pA-3tzqB:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujh | GLUCOSE-6-PHOSPHATEISOMERASE (Toxoplasmagondii) |
PF00342(PGI) | 4 | GLY A 256THR A 257SER A 258ASN A 253 | None | 0.73A | 5k4pA-3ujhA:undetectable | 5k4pA-3ujhA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wel | ALPHA-GLUCOSIDASE (Beta vulgaris) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16863(NtCtMGAM_N) | 4 | GLY A 429TYR A 427GLY A 400ASN A 475 | None | 0.85A | 5k4pA-3welA:undetectable | 5k4pA-3welA:16.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsq | ANTIBODY LIGHT CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | GLY L 24THR L 70SER L 71GLY L 69ASN L 28 | None | 1.20A | 5k4pA-3wsqL:undetectable | 5k4pA-3wsqL:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wuf | ENDO-1,4-BETA-XYLANASE A (Streptomycessp.) |
PF00331(Glyco_hydro_10) | 4 | GLY A 55SER A 77TYR A 53GLY A 44 | None | 0.89A | 5k4pA-3wufA:undetectable | 5k4pA-3wufA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wy8 | SERINE PROTEASE (Paenarthrobacternicotinovorans) |
no annotation | 4 | GLY A 12SER A 26TYR A 130GLY A 173 | None | 0.74A | 5k4pA-3wy8A:undetectable | 5k4pA-3wy8A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4awe | ENDO-BETA-D-1,4-MANNANASE (Neurosporasitophila) |
PF00150(Cellulase) | 4 | GLY A 347TYR A 364GLY A 350ASN A 356 | None | 0.65A | 5k4pA-4aweA:1.7 | 5k4pA-4aweA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxr | MALONYL COASYNTHETASE,BENZOATE-COA LIGASECHIMERIC PROTEIN (Rhodopseudomonaspalustris;Paraburkholderiaxenovorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | GLY A 323TYR A 391GLY A 320ASN A 311 | NoneNoneMLY A 412 ( 4.6A)None | 0.90A | 5k4pA-4gxrA:undetectable | 5k4pA-4gxrA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h09 | HYPOTHETICAL LEUCINERICH REPEAT PROTEIN (Eubacteriumventriosum) |
PF13306(LRR_5) | 4 | GLY A 265SER A 245TYR A 242GLY A 269 | NoneNoneNoneEDO A 506 (-3.9A) | 0.82A | 5k4pA-4h09A:undetectable | 5k4pA-4h09A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jf7 | HEMAGGLUTININ-NEURAMINIDASE (Mammalianrubulavirus 5) |
no annotation | 4 | GLY D 307SER D 360TYR D 306GLY D 361 | None | 0.92A | 5k4pA-4jf7D:undetectable | 5k4pA-4jf7D:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4juu | EPIMERASE (Xanthomonascampestris) |
PF05544(Pro_racemase) | 4 | GLY A 160THR A 240SER A 243GLY A 239 | NonePO4 A 404 ( 4.6A)NonePO4 A 404 (-3.6A) | 0.88A | 5k4pA-4juuA:undetectable | 5k4pA-4juuA:24.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7g | 3-HYDROXYPROLINEDEHYDRATSE (Agrobacteriumvitis) |
PF05544(Pro_racemase) | 4 | GLY B 171THR B 258SER B 261GLY B 257 | NonePYC B 904 (-2.8A)NonePYC B 904 (-3.7A) | 0.81A | 5k4pA-4k7gB:undetectable | 5k4pA-4k7gB:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k8l | PROLINE RACEMASE (Ochrobactrumanthropi) |
PF05544(Pro_racemase) | 4 | GLY A 170THR A 257SER A 260GLY A 256 | None | 0.90A | 5k4pA-4k8lA:undetectable | 5k4pA-4k8lA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k8l | PROLINE RACEMASE (Ochrobactrumanthropi) |
PF05544(Pro_racemase) | 4 | GLY A 171THR A 257SER A 260GLY A 256 | None | 0.79A | 5k4pA-4k8lA:undetectable | 5k4pA-4k8lA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lb0 | UNCHARACTERIZEDPROTEIN (Agrobacteriumvitis) |
PF05544(Pro_racemase) | 4 | GLY A 174THR A 257SER A 260GLY A 256 | NoneACT A 401 (-2.8A)NoneACT A 401 (-3.6A) | 0.87A | 5k4pA-4lb0A:undetectable | 5k4pA-4lb0A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lcc | BETA-2-MICROGLOBULIN, MHC CLASSI-RELATED PROTEIN (Bos taurus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLY C 349THR C 350SER C 346GLY C 317 | None | 0.92A | 5k4pA-4lccC:undetectable | 5k4pA-4lccC:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mks | ENOLASE 2 (Lactobacillusgasseri) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLY A 44THR A 43SER A 42GLY A 40 | None | 0.86A | 5k4pA-4mksA:undetectable | 5k4pA-4mksA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oon | PENICILLIN-BINDINGPROTEIN 1A (Pseudomonasaeruginosa) |
PF00905(Transpeptidase)PF00912(Transgly)PF17092(PCB_OB) | 4 | GLY A 729THR A 727SER A 702ASN A 384 | None | 0.88A | 5k4pA-4oonA:undetectable | 5k4pA-4oonA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p7w | L-PROLINECIS-4-HYDROXYLASE (Mesorhizobiumjaponicum) |
PF05118(Asp_Arg_Hydrox)PF05373(Pro_3_hydrox_C) | 4 | GLY A 50THR A 67GLY A 70ASN A 47 | None | 0.77A | 5k4pA-4p7wA:undetectable | 5k4pA-4p7wA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rpf | HOMOSERINE KINASE (Yersinia pestis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | GLY A 11SER A 260GLY A 95ASN A 142 | NoneNoneCIT A 401 (-3.3A)CIT A 401 (-3.3A) | 0.80A | 5k4pA-4rpfA:undetectable | 5k4pA-4rpfA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rqu | ALCOHOLDEHYDROGENASE (Arabidopsisthaliana) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 323THR A 181SER A 180GLY A 178 | NoneNoneNone ZN A 401 ( 4.8A) | 0.90A | 5k4pA-4rquA:undetectable | 5k4pA-4rquA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wlk | YUIC (Bacillussubtilis) |
PF06725(3D) | 4 | THR A 100SER A 99TYR A 93GLY A 96 | 3QL A 301 (-3.5A)3QL A 301 (-4.6A)3QL A 301 (-3.6A)None | 0.77A | 5k4pA-4wlkA:undetectable | 5k4pA-4wlkA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xpr | ALPHA-GLUCOSIDASE (Pseudopedobactersaltans) |
PF01055(Glyco_hydro_31)PF17137(DUF5110) | 4 | GLY A 424THR A 425SER A 426GLY A 222 | None | 0.80A | 5k4pA-4xprA:undetectable | 5k4pA-4xprA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xyb | FORMATEDEHYDROGENASE (Granulicellamallensis) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | GLY A 341SER A 146TYR A 345GLY A 148 | None | 0.73A | 5k4pA-4xybA:undetectable | 5k4pA-4xybA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzb | CELA (Geobacillus sp.70PC53) |
PF00150(Cellulase) | 4 | GLY A 233THR A 234SER A 235ASN A 264 | None | 0.85A | 5k4pA-4xzbA:undetectable | 5k4pA-4xzbA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzw | ENDO-GLUCANASECHIMERA C10 (unculturedbacterium;Geobacillus sp.70PC53) |
PF00150(Cellulase) | 4 | GLY A 232THR A 233SER A 234ASN A 263 | None | 0.81A | 5k4pA-4xzwA:undetectable | 5k4pA-4xzwA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zke | SUPERKILLER PROTEIN7 (Saccharomycescerevisiae) |
PF00009(GTP_EFTU) | 4 | THR A 282SER A 281GLY A 279ASN A 315 | THR A 282 (-0.8A)SER A 281 ( 0.0A)GLY A 279 (-0.0A)ASN A 315 (-0.6A) | 0.86A | 5k4pA-4zkeA:undetectable | 5k4pA-4zkeA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dkx | ALPHAGLUCOSIDASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 4 | GLY A 514SER A 521GLY A 519ASN A 564 | None | 0.83A | 5k4pA-5dkxA:undetectable | 5k4pA-5dkxA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ecu | CELLULASE (Caldicellulosiruptorsaccharolyticus) |
PF00150(Cellulase)PF03424(CBM_17_28) | 4 | GLY A 287THR A 288SER A 289ASN A 318 | None | 0.82A | 5k4pA-5ecuA:1.8 | 5k4pA-5ecuA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f9s | SERINE--PYRUVATEAMINOTRANSFERASE (Homo sapiens) |
PF00266(Aminotran_5) | 4 | GLY A 356THR A 355SER A 354GLY A 352 | None | 0.76A | 5k4pA-5f9sA:2.3 | 5k4pA-5f9sA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fip | GH5 CELLULASE (unidentified) |
PF00150(Cellulase)PF03424(CBM_17_28) | 4 | GLY A 296THR A 297SER A 298ASN A 327 | None | 0.84A | 5k4pA-5fipA:undetectable | 5k4pA-5fipA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fp1 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | GLY A 72TYR A 694GLY A 70ASN A 76 | None | 0.90A | 5k4pA-5fp1A:undetectable | 5k4pA-5fp1A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gs0 | TOLL-LIKE RECEPTOR 3 (Homo sapiens) |
PF13516(LRR_6)PF13855(LRR_8) | 4 | GLY A 594SER A 571GLY A 573ASN A 620 | None | 0.91A | 5k4pA-5gs0A:undetectable | 5k4pA-5gs0A:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hm2 | 3C PROTEINASE (Foot-and-mouthdisease virus) |
PF00548(Peptidase_C3) | 4 | GLY A 161TYR A 162GLY A 164ASN A 121 | None | 0.92A | 5k4pA-5hm2A:undetectable | 5k4pA-5hm2A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ie2 | OXALATE--COA LIGASE (Arabidopsisthaliana) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | GLY A 338TYR A 403GLY A 335ASN A 324 | None | 0.86A | 5k4pA-5ie2A:undetectable | 5k4pA-5ie2A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iqn | PROTEIN FIMG (Escherichiacoli) |
no annotation | 4 | GLY A 99THR A 98SER A 66GLY A 67 | None | 0.89A | 5k4pA-5iqnA:undetectable | 5k4pA-5iqnA:17.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5k4p | PROBABLEPHOSPHATIDYLETHANOLAMINE TRANSFERASEMCR-1 (Escherichiacoli) |
PF00884(Sulfatase) | 6 | GLY A 282THR A 283SER A 284TYR A 287GLY A 479ASN A 482 | SOR A 611 (-3.1A)SOR A 611 (-3.5A)SOR A 611 (-2.8A)SOR A 611 ( 4.0A)SOR A 611 (-3.8A)SOR A 611 (-3.1A) | 0.00A | 5k4pA-5k4pA:61.1 | 5k4pA-5k4pA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3q | SIGNAL RECOGNITIONPARTICLE RECEPTORSUBUNIT ALPHA (Homo sapiens) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | GLY B 615THR B 588GLY B 551ASN B 434 | GNP B 705 (-3.6A)GNP B 705 ( 4.6A)NoneGNP B 705 (-3.7A) | 0.83A | 5k4pA-5l3qB:4.6 | 5k4pA-5l3qB:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mes | LIGHT CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY L 69THR L 70SER L 71GLY L 24 | None | 0.86A | 5k4pA-5mesL:undetectable | 5k4pA-5mesL:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mio | KINESIN-LIKE PROTEINKIF2C,KIF2C FUSED TOA DARPIN,KIF2C FUSEDTO A DARPIN (Homo sapiens) |
PF00023(Ank)PF00225(Kinesin)PF12796(Ank_2) | 4 | GLY C 351THR C 350GLY C 495ASN C 464 | ANP C 802 (-3.5A)ANP C 802 (-2.5A)ANP C 802 (-3.0A)ANP C 802 (-3.2A) | 0.81A | 5k4pA-5mioC:undetectable | 5k4pA-5mioC:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mtv | EH DOMAIN-CONTAININGPROTEIN 4 (Mus musculus) |
PF00350(Dynamin_N)PF16880(EHD_N) | 4 | GLY A 73THR A 72SER A 71ASN A 222 | AGS A1000 (-3.1A)NoneAGS A1000 (-3.0A)AGS A1000 (-3.2A) | 0.80A | 5k4pA-5mtvA:undetectable | 5k4pA-5mtvA:20.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mx9 | PHOSPHATIDYLETHANOLAMINE TRANSFERASEMCR-2 (Escherichiacoli) |
PF00884(Sulfatase) | 6 | GLY A 282THR A 283SER A 284TYR A 287GLY A 479ASN A 482 | None | 0.25A | 5k4pA-5mx9A:56.8 | 5k4pA-5mx9A:82.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t4y | SUSC HOMOLOG (Bacteroidesthetaiotaomicron) |
no annotation | 4 | GLY D 655THR D 656GLY D 672ASN D 642 | None | 0.76A | 5k4pA-5t4yD:undetectable | 5k4pA-5t4yD:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t4z | ANTIBODY DH501 FABLIGHT CHAIN (Macaca mulatta) |
no annotation | 4 | GLY L 68THR L 69SER L 70GLY L 25 | None | 0.86A | 5k4pA-5t4zL:undetectable | 5k4pA-5t4zL:24.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uq6 | TARTRATE-RESISTANTACID PHOSPHATASETYPE 5 (Sus scrofa) |
PF00149(Metallophos) | 4 | GLY A 272SER A 239GLY A 13ASN A 31 | None | 0.72A | 5k4pA-5uq6A:undetectable | 5k4pA-5uq6A:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wve | APOPTOTICPROTEASE-ACTIVATINGFACTOR 1 (Homo sapiens) |
PF00400(WD40)PF00931(NB-ARC) | 4 | GLY A1197THR A1218TYR A1198GLY A1217 | None | 0.90A | 5k4pA-5wveA:undetectable | 5k4pA-5wveA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnu | PUTATIVE INTEGRALMEMBRANE PROTEIN (Escherichiacoli) |
no annotation | 6 | GLY A 280THR A 281SER A 282TYR A 285GLY A 477ASN A 480 | None | 0.37A | 5k4pA-5xnuA:56.7 | 5k4pA-5xnuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwz | UNPLACED GENOMICSCAFFOLDSUPERCONT1.36, WHOLEGENOME SHOTGUNSEQUENCE (Cladophialophorabantiana) |
no annotation | 4 | GLY A 80THR A 110SER A 109GLY A 107 | None | 0.83A | 5k4pA-5xwzA:undetectable | 5k4pA-5xwzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y10 | MEMBRANEGLYCOPROTEINPOLYPROTEIN (SFTSphlebovirus) |
PF07243(Phlebovirus_G1) | 4 | GLY C 161THR C 162SER C 163GLY C 146 | None | 0.59A | 5k4pA-5y10C:undetectable | 5k4pA-5y10C:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yv5 | ATPASE RIL (Pyrococcusfuriosus) |
no annotation | 4 | GLY A 291THR A 110TYR A 290GLY A 109 | NoneADP A 601 (-4.6A)NoneADP A 601 (-3.8A) | 0.89A | 5k4pA-5yv5A:undetectable | 5k4pA-5yv5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z97 | LACTONASE FORPROTEIN (Rhinocladiellamackenziei) |
no annotation | 4 | GLY A 80THR A 110SER A 109GLY A 107 | None | 0.85A | 5k4pA-5z97A:undetectable | 5k4pA-5z97A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bnf | PHOSPHOETHANOLAMINETRANSFERASE (Moraxella sp.HMSC061H09) |
no annotation | 5 | GLY A 312THR A 313SER A 314TYR A 317GLY A 512 | GOL A 610 ( 3.8A)GOL A 610 (-3.8A)PO4 A 601 (-3.9A)GOL A 610 (-4.0A)None | 0.16A | 5k4pA-6bnfA:52.6 | 5k4pA-6bnfA:undetectable |