SIMILAR PATTERNS OF AMINO ACIDS FOR 5K4P_A_SORA611

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cdo ALCOHOL
DEHYDROGENASE


(Gadus morhua)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 320
THR A 179
SER A 178
GLY A 176
None
NAD  A 375 (-3.1A)
None
None
0.90A 5k4pA-1cdoA:
0.0
5k4pA-1cdoA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csj HEPATITIS C VIRUS
RNA POLYMERASE
(NS5B)


(Hepacivirus C)
PF00998
(RdRP_3)
4 GLY A 275
THR A   7
GLY A   8
ASN A 273
None
0.87A 5k4pA-1csjA:
undetectable
5k4pA-1csjA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d1t ALCOHOL
DEHYDROGENASE CLASS
IV SIGMA CHAIN


(Homo sapiens)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 320
THR A 178
SER A 177
GLY A 175
None
NAD  A1377 (-2.8A)
None
NAD  A1377 ( 4.8A)
0.82A 5k4pA-1d1tA:
undetectable
5k4pA-1d1tA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dpp DIPEPTIDE BINDING
PROTEIN


(Escherichia
coli)
PF00496
(SBP_bac_5)
4 GLY A 183
THR A 182
TYR A 204
ASN A  34
None
0.69A 5k4pA-1dppA:
0.0
5k4pA-1dppA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee2 ALCOHOL
DEHYDROGENASE


(Equus caballus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 319
THR A 177
SER A 176
GLY A 174
None
NAD  A1100 (-3.3A)
None
None
0.90A 5k4pA-1ee2A:
0.0
5k4pA-1ee2A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5j BETA-1,4-XYLANASE

(Dictyoglomus
thermophilum)
PF00457
(Glyco_hydro_11)
4 GLY A  49
THR A  48
TYR A  13
ASN A 193
None
0.92A 5k4pA-1f5jA:
undetectable
5k4pA-1f5jA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fno PEPTIDASE T

(Salmonella
enterica)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
5 GLY A 355
THR A 356
TYR A 319
GLY A 358
ASN A 207
SO4  A 600 (-4.1A)
None
SO4  A 600 (-4.8A)
None
None
1.33A 5k4pA-1fnoA:
0.5
5k4pA-1fnoA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g01 ENDOGLUCANASE

(Bacillus sp.
KSM-635)
PF00150
(Cellulase)
PF03424
(CBM_17_28)
4 GLY A 487
THR A 488
SER A 489
ASN A 518
None
0.80A 5k4pA-1g01A:
1.6
5k4pA-1g01A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus)
PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim)
4 GLY B 434
THR B 436
SER B 437
GLY B 447
None
0.73A 5k4pA-1gl9B:
0.0
5k4pA-1gl9B:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i77 CYTOCHROME C3

(Desulfovibrio
desulfuricans)
PF02085
(Cytochrom_CIII)
4 GLY A  60
SER A  63
TYR A  66
GLY A  57
None
0.86A 5k4pA-1i77A:
undetectable
5k4pA-1i77A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mac 1,3-1,4-BETA-D-GLUCA
N 4-GLUCANOHYDROLASE


(Paenibacillus
macerans)
PF00722
(Glyco_hydro_16)
4 THR A  83
TYR A 194
GLY A 192
ASN A 195
None
0.89A 5k4pA-1macA:
undetectable
5k4pA-1macA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)


(Cardiovirus A)
no annotation 4 GLY 1 149
THR 1 148
GLY 1 223
ASN 1 219
None
0.89A 5k4pA-1mec1:
undetectable
5k4pA-1mec1:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlr ENDO-1,4-BETA-GLUCAN
ASE


(Streptomyces
lividans)
PF01670
(Glyco_hydro_12)
4 GLY A  92
SER A 170
GLY A 171
ASN A 214
None
0.92A 5k4pA-1nlrA:
undetectable
5k4pA-1nlrA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvh LEUKEMIA INHIBITORY
FACTOR


(Homo sapiens)
PF01291
(LIF_OSM)
4 GLY B  91
THR B  92
SER B  93
GLY B 147
None
0.82A 5k4pA-1pvhB:
undetectable
5k4pA-1pvhB:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rjc CAMELID HEAVY CHAIN
ANTIBODY


(Camelus
dromedarius)
PF07686
(V-set)
4 GLY A 109
THR A 110
TYR A 114
GLY A  47
None
0.69A 5k4pA-1rjcA:
undetectable
5k4pA-1rjcA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rk2 RIBOKINASE

(Escherichia
coli)
PF00294
(PfkB)
5 GLY A  96
THR A  95
SER A  94
GLY A  65
ASN A 117
None
1.18A 5k4pA-1rk2A:
undetectable
5k4pA-1rk2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3t ALCOHOL
DEHYDROGENASE ALPHA
CHAIN


(Homo sapiens)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 320
THR A 178
SER A 177
GLY A 175
None
NAD  A1377 (-3.0A)
None
None
0.85A 5k4pA-1u3tA:
undetectable
5k4pA-1u3tA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wji TUDOR DOMAIN
CONTAINING PROTEIN 3


(Homo sapiens)
PF00627
(UBA)
4 GLY A   7
SER A   5
GLY A   1
ASN A  35
None
0.77A 5k4pA-1wjiA:
undetectable
5k4pA-1wjiA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfz HYPOXANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE


(Caldanaerobacter
subterraneus)
PF00156
(Pribosyltran)
4 GLY A  80
THR A  76
SER A  75
GLY A  73
None
0.85A 5k4pA-1yfzA:
undetectable
5k4pA-1yfzA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yub RRNA
METHYLTRANSFERASE


(Streptococcus
pneumoniae)
PF00398
(RrnaAD)
4 GLY A  37
THR A  38
GLY A  39
ASN A 100
None
0.90A 5k4pA-1yubA:
undetectable
5k4pA-1yubA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aa4 PUTATIVE
N-ACETYLMANNOSAMINE
KINASE


(Escherichia
coli)
PF00480
(ROK)
4 GLY A   9
THR A  64
SER A  63
GLY A  65
None
0.87A 5k4pA-2aa4A:
undetectable
5k4pA-2aa4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azp HYPOTHETICAL PROTEIN
PA1268


(Pseudomonas
aeruginosa)
PF05544
(Pro_racemase)
4 GLY A 160
THR A 238
SER A 241
GLY A 237
None
0.87A 5k4pA-2azpA:
undetectable
5k4pA-2azpA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bq8 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5


(Homo sapiens)
PF00149
(Metallophos)
4 GLY X 270
SER X 237
GLY X  11
ASN X  29
None
0.67A 5k4pA-2bq8X:
undetectable
5k4pA-2bq8X:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fzw ALCOHOL
DEHYDROGENASE CLASS
III CHI CHAIN


(Homo sapiens)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 319
THR A 177
SER A 176
GLY A 174
None
NAD  A1377 (-3.0A)
None
NAD  A1377 ( 4.4A)
0.79A 5k4pA-2fzwA:
undetectable
5k4pA-2fzwA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj9 AUTOINDUCER
2-BINDING
PERIPLASMIC PROTEIN
LUXP


(Vibrio harveyi)
PF13407
(Peripla_BP_4)
4 GLY A 316
THR A 315
GLY A 177
ASN A  85
None
0.80A 5k4pA-2hj9A:
undetectable
5k4pA-2hj9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzk TRAP-T FAMILY
SORBITOL/MANNITOL
TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN, SMOM


(Rhodobacter
sphaeroides)
PF03480
(DctP)
4 GLY A 242
SER A 119
GLY A 122
ASN A 152
None
0.79A 5k4pA-2hzkA:
undetectable
5k4pA-2hzkA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j92 PICORNAIN 3C

(Foot-and-mouth
disease virus)
PF00548
(Peptidase_C3)
4 GLY A 161
TYR A 162
GLY A 164
ASN A 121
None
0.92A 5k4pA-2j92A:
undetectable
5k4pA-2j92A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o14 HYPOTHETICAL PROTEIN
YXIM


(Bacillus
subtilis)
PF13472
(Lipase_GDSL_2)
4 GLY A 209
SER A 207
GLY A 169
ASN A 241
None
0.92A 5k4pA-2o14A:
undetectable
5k4pA-2o14A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qj6 TOXIN A

(Clostridioides
difficile)
PF01473
(CW_binding_1)
4 GLY A 129
THR A 128
TYR A 139
GLY A 144
GLY  A 129 ( 0.0A)
THR  A 128 ( 0.8A)
TYR  A 139 ( 1.3A)
GLY  A 144 ( 0.0A)
0.91A 5k4pA-2qj6A:
undetectable
5k4pA-2qj6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rff PUTATIVE
NUCLEOTIDYLTRANSFERA
SE


(Sulfolobus
solfataricus)
PF01909
(NTP_transf_2)
4 GLY A  44
SER A  40
TYR A  46
GLY A  39
None
0.81A 5k4pA-2rffA:
undetectable
5k4pA-2rffA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vca ALPHA-N-ACETYLGLUCOS
AMINIDASE


(Clostridium
perfringens)
PF00754
(F5_F8_type_C)
PF05089
(NAGLU)
PF12971
(NAGLU_N)
PF12972
(NAGLU_C)
4 GLY A 376
SER A 359
TYR A 363
ASN A 803
None
0.75A 5k4pA-2vcaA:
undetectable
5k4pA-2vcaA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqp POLYSIALIC ACID
CAPSULE BIOSYNTHESIS
PROTEIN SIAC


(Neisseria
meningitidis)
PF03102
(NeuB)
PF08666
(SAF)
4 GLY A 156
SER A 154
GLY A 131
ASN A 184
None
WQP  A1350 (-2.5A)
WQP  A1350 ( 3.8A)
WQP  A1350 (-3.5A)
0.87A 5k4pA-2wqpA:
undetectable
5k4pA-2wqpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8p CHOLINE-BINDING
PROTEIN F


(Streptococcus
pneumoniae)
PF01473
(CW_binding_1)
5 GLY A 213
THR A 212
TYR A 223
GLY A 229
ASN A 226
None
1.27A 5k4pA-2x8pA:
undetectable
5k4pA-2x8pA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
4 GLY A 269
THR A 268
GLY A 266
ASN A 262
None
0.92A 5k4pA-2xybA:
undetectable
5k4pA-2xybA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a3h ENDOGLUCANASE

(Salipaludibacillus
agaradhaerens)
PF00150
(Cellulase)
4 GLY A 230
THR A 231
SER A 232
ASN A 261
None
0.88A 5k4pA-3a3hA:
undetectable
5k4pA-3a3hA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cos ALCOHOL
DEHYDROGENASE 4


(Homo sapiens)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 326
THR A 184
SER A 183
GLY A 181
None
NAD  A 400 (-3.0A)
None
None
0.80A 5k4pA-3cosA:
undetectable
5k4pA-3cosA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cp7 ALKALINE SERINE
PROTEASE AL20


(Nesterenkonia
aethiopica)
PF13365
(Trypsin_2)
4 GLY A  10
SER A  24
TYR A 130
GLY A 171
None
0.73A 5k4pA-3cp7A:
undetectable
5k4pA-3cp7A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8k ALPHA-AMYLASE, SUSG

(Bacteroides
thetaiotaomicron)
PF00128
(Alpha-amylase)
4 GLY A 362
SER A 364
TYR A 367
GLY A 356
None
0.70A 5k4pA-3k8kA:
undetectable
5k4pA-3k8kA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8u HEME-BINDING PROTEIN
A


(Glaesserella
parasuis)
PF00496
(SBP_bac_5)
4 GLY A 207
THR A 206
TYR A 228
ASN A  58
None
0.75A 5k4pA-3m8uA:
undetectable
5k4pA-3m8uA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mq2 16S RRNA
METHYLTRANSFERASE


(Streptoalloteichus
tenebrarius)
PF02390
(Methyltransf_4)
4 GLY A 130
THR A 212
SER A 132
GLY A 211
None
0.91A 5k4pA-3mq2A:
undetectable
5k4pA-3mq2A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nps S4 FAB LIGHT CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 GLY C  68
THR C  69
SER C  70
GLY C  25
None
0.90A 5k4pA-3npsC:
undetectable
5k4pA-3npsC:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE


(Synechocystis
sp. PCC 6803)
no annotation 4 THR B 783
SER B 784
TYR B 787
GLY B 780
None
0.80A 5k4pA-3ohwB:
undetectable
5k4pA-3ohwB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8k HYDROLASE,
CARBON-NITROGEN
FAMILY


(Staphylococcus
aureus)
PF00795
(CN_hydrolase)
5 GLY A 202
THR A 201
SER A 200
TYR A 209
GLY A 211
None
1.49A 5k4pA-3p8kA:
undetectable
5k4pA-3p8kA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3phf ENVELOPE
GLYCOPROTEIN H


(Human
gammaherpesvirus
4)
no annotation 4 GLY A 394
THR A 397
SER A 398
ASN A 442
None
0.80A 5k4pA-3phfA:
undetectable
5k4pA-3phfA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzu ENDOGLUCANASE

(Bacillus
subtilis)
PF00150
(Cellulase)
4 GLY A 259
THR A 260
SER A 261
ASN A 290
None
0.83A 5k4pA-3pzuA:
undetectable
5k4pA-3pzuA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qs3 FIMBRILLIN MATB
HOMOLOG, ECPD


(Escherichia
coli)
PF16449
(MatB)
5 GLY A 140
THR A 141
SER A  81
GLY A 144
ASN A  84
None
1.36A 5k4pA-3qs3A:
undetectable
5k4pA-3qs3A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1


(Mus musculus)
PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40)
4 GLY A1198
THR A1219
TYR A1199
GLY A1218
None
0.79A 5k4pA-3sfzA:
undetectable
5k4pA-3sfzA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpa HEME-BINDING PROTEIN
A


(Glaesserella
parasuis)
PF00496
(SBP_bac_5)
4 GLY A 190
THR A 189
TYR A 211
ASN A  41
None
0.72A 5k4pA-3tpaA:
undetectable
5k4pA-3tpaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tzq SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE


(Mycobacterium
marinum)
no annotation 4 GLY B  20
THR B  23
SER B  24
ASN B  88
None
0.87A 5k4pA-3tzqB:
undetectable
5k4pA-3tzqB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujh GLUCOSE-6-PHOSPHATE
ISOMERASE


(Toxoplasma
gondii)
PF00342
(PGI)
4 GLY A 256
THR A 257
SER A 258
ASN A 253
None
0.73A 5k4pA-3ujhA:
undetectable
5k4pA-3ujhA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N)
4 GLY A 429
TYR A 427
GLY A 400
ASN A 475
None
0.85A 5k4pA-3welA:
undetectable
5k4pA-3welA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsq ANTIBODY LIGHT CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 GLY L  24
THR L  70
SER L  71
GLY L  69
ASN L  28
None
1.20A 5k4pA-3wsqL:
undetectable
5k4pA-3wsqL:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wuf ENDO-1,4-BETA-XYLANA
SE A


(Streptomyces
sp.)
PF00331
(Glyco_hydro_10)
4 GLY A  55
SER A  77
TYR A  53
GLY A  44
None
0.89A 5k4pA-3wufA:
undetectable
5k4pA-3wufA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wy8 SERINE PROTEASE

(Paenarthrobacter
nicotinovorans)
no annotation 4 GLY A  12
SER A  26
TYR A 130
GLY A 173
None
0.74A 5k4pA-3wy8A:
undetectable
5k4pA-3wy8A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awe ENDO-BETA-D-1,4-MANN
ANASE


(Neurospora
sitophila)
PF00150
(Cellulase)
4 GLY A 347
TYR A 364
GLY A 350
ASN A 356
None
0.65A 5k4pA-4aweA:
1.7
5k4pA-4aweA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxr MALONYL COA
SYNTHETASE,
BENZOATE-COA LIGASE
CHIMERIC PROTEIN


(Rhodopseudomonas
palustris;
Paraburkholderia
xenovorans)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 GLY A 323
TYR A 391
GLY A 320
ASN A 311
None
None
MLY  A 412 ( 4.6A)
None
0.90A 5k4pA-4gxrA:
undetectable
5k4pA-4gxrA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN


(Eubacterium
ventriosum)
PF13306
(LRR_5)
4 GLY A 265
SER A 245
TYR A 242
GLY A 269
None
None
None
EDO  A 506 (-3.9A)
0.82A 5k4pA-4h09A:
undetectable
5k4pA-4h09A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jf7 HEMAGGLUTININ-NEURAM
INIDASE


(Mammalian
rubulavirus 5)
no annotation 4 GLY D 307
SER D 360
TYR D 306
GLY D 361
None
0.92A 5k4pA-4jf7D:
undetectable
5k4pA-4jf7D:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4juu EPIMERASE

(Xanthomonas
campestris)
PF05544
(Pro_racemase)
4 GLY A 160
THR A 240
SER A 243
GLY A 239
None
PO4  A 404 ( 4.6A)
None
PO4  A 404 (-3.6A)
0.88A 5k4pA-4juuA:
undetectable
5k4pA-4juuA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7g 3-HYDROXYPROLINE
DEHYDRATSE


(Agrobacterium
vitis)
PF05544
(Pro_racemase)
4 GLY B 171
THR B 258
SER B 261
GLY B 257
None
PYC  B 904 (-2.8A)
None
PYC  B 904 (-3.7A)
0.81A 5k4pA-4k7gB:
undetectable
5k4pA-4k7gB:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k8l PROLINE RACEMASE

(Ochrobactrum
anthropi)
PF05544
(Pro_racemase)
4 GLY A 170
THR A 257
SER A 260
GLY A 256
None
0.90A 5k4pA-4k8lA:
undetectable
5k4pA-4k8lA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k8l PROLINE RACEMASE

(Ochrobactrum
anthropi)
PF05544
(Pro_racemase)
4 GLY A 171
THR A 257
SER A 260
GLY A 256
None
0.79A 5k4pA-4k8lA:
undetectable
5k4pA-4k8lA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lb0 UNCHARACTERIZED
PROTEIN


(Agrobacterium
vitis)
PF05544
(Pro_racemase)
4 GLY A 174
THR A 257
SER A 260
GLY A 256
None
ACT  A 401 (-2.8A)
None
ACT  A 401 (-3.6A)
0.87A 5k4pA-4lb0A:
undetectable
5k4pA-4lb0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcc BETA-2-MICROGLOBULIN
, MHC CLASS
I-RELATED PROTEIN


(Bos taurus)
PF00129
(MHC_I)
PF07654
(C1-set)
4 GLY C 349
THR C 350
SER C 346
GLY C 317
None
0.92A 5k4pA-4lccC:
undetectable
5k4pA-4lccC:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mks ENOLASE 2

(Lactobacillus
gasseri)
PF00113
(Enolase_C)
PF03952
(Enolase_N)
4 GLY A  44
THR A  43
SER A  42
GLY A  40
None
0.86A 5k4pA-4mksA:
undetectable
5k4pA-4mksA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oon PENICILLIN-BINDING
PROTEIN 1A


(Pseudomonas
aeruginosa)
PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB)
4 GLY A 729
THR A 727
SER A 702
ASN A 384
None
0.88A 5k4pA-4oonA:
undetectable
5k4pA-4oonA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7w L-PROLINE
CIS-4-HYDROXYLASE


(Mesorhizobium
japonicum)
PF05118
(Asp_Arg_Hydrox)
PF05373
(Pro_3_hydrox_C)
4 GLY A  50
THR A  67
GLY A  70
ASN A  47
None
0.77A 5k4pA-4p7wA:
undetectable
5k4pA-4p7wA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rpf HOMOSERINE KINASE

(Yersinia pestis)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
4 GLY A  11
SER A 260
GLY A  95
ASN A 142
None
None
CIT  A 401 (-3.3A)
CIT  A 401 (-3.3A)
0.80A 5k4pA-4rpfA:
undetectable
5k4pA-4rpfA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rqu ALCOHOL
DEHYDROGENASE


(Arabidopsis
thaliana)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLY A 323
THR A 181
SER A 180
GLY A 178
None
None
None
ZN  A 401 ( 4.8A)
0.90A 5k4pA-4rquA:
undetectable
5k4pA-4rquA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wlk YUIC

(Bacillus
subtilis)
PF06725
(3D)
4 THR A 100
SER A  99
TYR A  93
GLY A  96
3QL  A 301 (-3.5A)
3QL  A 301 (-4.6A)
3QL  A 301 (-3.6A)
None
0.77A 5k4pA-4wlkA:
undetectable
5k4pA-4wlkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xpr ALPHA-GLUCOSIDASE

(Pseudopedobacter
saltans)
PF01055
(Glyco_hydro_31)
PF17137
(DUF5110)
4 GLY A 424
THR A 425
SER A 426
GLY A 222
None
0.80A 5k4pA-4xprA:
undetectable
5k4pA-4xprA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyb FORMATE
DEHYDROGENASE


(Granulicella
mallensis)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 GLY A 341
SER A 146
TYR A 345
GLY A 148
None
0.73A 5k4pA-4xybA:
undetectable
5k4pA-4xybA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzb CELA

(Geobacillus sp.
70PC53)
PF00150
(Cellulase)
4 GLY A 233
THR A 234
SER A 235
ASN A 264
None
0.85A 5k4pA-4xzbA:
undetectable
5k4pA-4xzbA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzw ENDO-GLUCANASE
CHIMERA C10


(uncultured
bacterium;
Geobacillus sp.
70PC53)
PF00150
(Cellulase)
4 GLY A 232
THR A 233
SER A 234
ASN A 263
None
0.81A 5k4pA-4xzwA:
undetectable
5k4pA-4xzwA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zke SUPERKILLER PROTEIN
7


(Saccharomyces
cerevisiae)
PF00009
(GTP_EFTU)
4 THR A 282
SER A 281
GLY A 279
ASN A 315
THR  A 282 (-0.8A)
SER  A 281 ( 0.0A)
GLY  A 279 (-0.0A)
ASN  A 315 (-0.6A)
0.86A 5k4pA-4zkeA:
undetectable
5k4pA-4zkeA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dkx ALPHA
GLUCOSIDASE-LIKE
PROTEIN


(Chaetomium
thermophilum)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110)
4 GLY A 514
SER A 521
GLY A 519
ASN A 564
None
0.83A 5k4pA-5dkxA:
undetectable
5k4pA-5dkxA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ecu CELLULASE

(Caldicellulosiruptor
saccharolyticus)
PF00150
(Cellulase)
PF03424
(CBM_17_28)
4 GLY A 287
THR A 288
SER A 289
ASN A 318
None
0.82A 5k4pA-5ecuA:
1.8
5k4pA-5ecuA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9s SERINE--PYRUVATE
AMINOTRANSFERASE


(Homo sapiens)
PF00266
(Aminotran_5)
4 GLY A 356
THR A 355
SER A 354
GLY A 352
None
0.76A 5k4pA-5f9sA:
2.3
5k4pA-5f9sA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fip GH5 CELLULASE

(unidentified)
PF00150
(Cellulase)
PF03424
(CBM_17_28)
4 GLY A 296
THR A 297
SER A 298
ASN A 327
None
0.84A 5k4pA-5fipA:
undetectable
5k4pA-5fipA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp1 TONB-DEPENDENT
SIDEROPHORE RECEPTOR


(Acinetobacter
baumannii)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 GLY A  72
TYR A 694
GLY A  70
ASN A  76
None
0.90A 5k4pA-5fp1A:
undetectable
5k4pA-5fp1A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs0 TOLL-LIKE RECEPTOR 3

(Homo sapiens)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 GLY A 594
SER A 571
GLY A 573
ASN A 620
None
0.91A 5k4pA-5gs0A:
undetectable
5k4pA-5gs0A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm2 3C PROTEINASE

(Foot-and-mouth
disease virus)
PF00548
(Peptidase_C3)
4 GLY A 161
TYR A 162
GLY A 164
ASN A 121
None
0.92A 5k4pA-5hm2A:
undetectable
5k4pA-5hm2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ie2 OXALATE--COA LIGASE

(Arabidopsis
thaliana)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 GLY A 338
TYR A 403
GLY A 335
ASN A 324
None
0.86A 5k4pA-5ie2A:
undetectable
5k4pA-5ie2A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iqn PROTEIN FIMG

(Escherichia
coli)
no annotation 4 GLY A  99
THR A  98
SER A  66
GLY A  67
None
0.89A 5k4pA-5iqnA:
undetectable
5k4pA-5iqnA:
17.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5k4p PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1


(Escherichia
coli)
PF00884
(Sulfatase)
6 GLY A 282
THR A 283
SER A 284
TYR A 287
GLY A 479
ASN A 482
SOR  A 611 (-3.1A)
SOR  A 611 (-3.5A)
SOR  A 611 (-2.8A)
SOR  A 611 ( 4.0A)
SOR  A 611 (-3.8A)
SOR  A 611 (-3.1A)
0.00A 5k4pA-5k4pA:
61.1
5k4pA-5k4pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3q SIGNAL RECOGNITION
PARTICLE RECEPTOR
SUBUNIT ALPHA


(Homo sapiens)
PF00448
(SRP54)
PF02881
(SRP54_N)
4 GLY B 615
THR B 588
GLY B 551
ASN B 434
GNP  B 705 (-3.6A)
GNP  B 705 ( 4.6A)
None
GNP  B 705 (-3.7A)
0.83A 5k4pA-5l3qB:
4.6
5k4pA-5l3qB:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mes LIGHT CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 GLY L  69
THR L  70
SER L  71
GLY L  24
None
0.86A 5k4pA-5mesL:
undetectable
5k4pA-5mesL:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mio KINESIN-LIKE PROTEIN
KIF2C,KIF2C FUSED TO
A DARPIN,KIF2C FUSED
TO A DARPIN


(Homo sapiens)
PF00023
(Ank)
PF00225
(Kinesin)
PF12796
(Ank_2)
4 GLY C 351
THR C 350
GLY C 495
ASN C 464
ANP  C 802 (-3.5A)
ANP  C 802 (-2.5A)
ANP  C 802 (-3.0A)
ANP  C 802 (-3.2A)
0.81A 5k4pA-5mioC:
undetectable
5k4pA-5mioC:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtv EH DOMAIN-CONTAINING
PROTEIN 4


(Mus musculus)
PF00350
(Dynamin_N)
PF16880
(EHD_N)
4 GLY A  73
THR A  72
SER A  71
ASN A 222
AGS  A1000 (-3.1A)
None
AGS  A1000 (-3.0A)
AGS  A1000 (-3.2A)
0.80A 5k4pA-5mtvA:
undetectable
5k4pA-5mtvA:
20.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mx9 PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-2


(Escherichia
coli)
PF00884
(Sulfatase)
6 GLY A 282
THR A 283
SER A 284
TYR A 287
GLY A 479
ASN A 482
None
0.25A 5k4pA-5mx9A:
56.8
5k4pA-5mx9A:
82.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t4y SUSC HOMOLOG

(Bacteroides
thetaiotaomicron)
no annotation 4 GLY D 655
THR D 656
GLY D 672
ASN D 642
None
0.76A 5k4pA-5t4yD:
undetectable
5k4pA-5t4yD:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t4z ANTIBODY DH501 FAB
LIGHT CHAIN


(Macaca mulatta)
no annotation 4 GLY L  68
THR L  69
SER L  70
GLY L  25
None
0.86A 5k4pA-5t4zL:
undetectable
5k4pA-5t4zL:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5


(Sus scrofa)
PF00149
(Metallophos)
4 GLY A 272
SER A 239
GLY A  13
ASN A  31
None
0.72A 5k4pA-5uq6A:
undetectable
5k4pA-5uq6A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wve APOPTOTIC
PROTEASE-ACTIVATING
FACTOR 1


(Homo sapiens)
PF00400
(WD40)
PF00931
(NB-ARC)
4 GLY A1197
THR A1218
TYR A1198
GLY A1217
None
0.90A 5k4pA-5wveA:
undetectable
5k4pA-5wveA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnu PUTATIVE INTEGRAL
MEMBRANE PROTEIN


(Escherichia
coli)
no annotation 6 GLY A 280
THR A 281
SER A 282
TYR A 285
GLY A 477
ASN A 480
None
0.37A 5k4pA-5xnuA:
56.7
5k4pA-5xnuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE


(Cladophialophora
bantiana)
no annotation 4 GLY A  80
THR A 110
SER A 109
GLY A 107
None
0.83A 5k4pA-5xwzA:
undetectable
5k4pA-5xwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y10 MEMBRANE
GLYCOPROTEIN
POLYPROTEIN


(SFTS
phlebovirus)
PF07243
(Phlebovirus_G1)
4 GLY C 161
THR C 162
SER C 163
GLY C 146
None
0.59A 5k4pA-5y10C:
undetectable
5k4pA-5y10C:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yv5 ATPASE RIL

(Pyrococcus
furiosus)
no annotation 4 GLY A 291
THR A 110
TYR A 290
GLY A 109
None
ADP  A 601 (-4.6A)
None
ADP  A 601 (-3.8A)
0.89A 5k4pA-5yv5A:
undetectable
5k4pA-5yv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z97 LACTONASE FOR
PROTEIN


(Rhinocladiella
mackenziei)
no annotation 4 GLY A  80
THR A 110
SER A 109
GLY A 107
None
0.85A 5k4pA-5z97A:
undetectable
5k4pA-5z97A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bnf PHOSPHOETHANOLAMINE
TRANSFERASE


(Moraxella sp.
HMSC061H09)
no annotation 5 GLY A 312
THR A 313
SER A 314
TYR A 317
GLY A 512
GOL  A 610 ( 3.8A)
GOL  A 610 (-3.8A)
PO4  A 601 (-3.9A)
GOL  A 610 (-4.0A)
None
0.16A 5k4pA-6bnfA:
52.6
5k4pA-6bnfA:
undetectable