SIMILAR PATTERNS OF AMINO ACIDS FOR 5JW1_B_CELB602_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amu GRAMICIDIN
SYNTHETASE 1

(Brevibacillus
brevis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 VAL A 317
VAL A 284
ILE A 259
PHE A 229
 None
 0.87A 5jw1B-1amuA:
0.0		 5jw1B-1amuA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1avw TRYPSIN INHIBITOR

(Glycine max) 		PF00197
(Kunitz_legume) 		4 VAL B 670
SER B 521
ILE B 519
PHE B 673
 None
 1.03A 5jw1B-1avwB:
0.0		 5jw1B-1avwB:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0w DIPHTHERIA TOXIN
REPRESSOR

(Corynebacterium
diphtheriae) 		PF01325
(Fe_dep_repress)
PF02742
(Fe_dep_repr_C) 		4 VAL A  56
SER A  61
ARG A  29
ILE A  15
 None
 1.00A 5jw1B-1c0wA:
0.0		 5jw1B-1c0wA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cfr RESTRICTION
ENDONUCLEASE

(Citrobacter
freundii) 		PF07832
(Bse634I) 		4 VAL A  22
SER A  26
ILE A  30
PHE A 156
 None
 0.93A 5jw1B-1cfrA:
0.0		 5jw1B-1cfrA:
18.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 VAL A 116
VAL A 349
SER A 353
ILE A 517
 None
SCL  A 700 ( 4.6A)
None
None
 0.25A 5jw1B-1ebvA:
57.4		 5jw1B-1ebvA:
64.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 VAL A 349
SER A 353
ILE A 517
PHE A 518
 SCL  A 700 ( 4.6A)
None
None
None
 0.78A 5jw1B-1ebvA:
57.4		 5jw1B-1ebvA:
64.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1es6 MATRIX PROTEIN VP40

(Ebola virus sp.) 		PF07447
(VP40) 		4 VAL A 162
SER A 316
ARG A 214
ILE A 216
 None
 0.95A 5jw1B-1es6A:
0.0		 5jw1B-1es6A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5t DIPHTHERIA TOXIN
REPRESSOR

(Corynebacterium
diphtheriae) 		PF01325
(Fe_dep_repress)
PF02742
(Fe_dep_repr_C) 		4 VAL A1056
SER A1061
ARG A1029
ILE A1015
 None
 1.06A 5jw1B-1f5tA:
undetectable		 5jw1B-1f5tA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f82 BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 VAL A 205
VAL A 201
SER A 221
ILE A 382
 None
 1.07A 5jw1B-1f82A:
0.0		 5jw1B-1f82A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyb NICOTINAMIDE
MONONUCLEOTIDE
ADENYLYLTRANSFERASE

(Methanothermobacter
thermautotrophicus) 		PF01467
(CTP_transf_like) 		4 VAL A 153
VAL A 135
ARG A 165
ILE A  46
 None
 1.06A 5jw1B-1hybA:
undetectable		 5jw1B-1hybA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhy METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox) 		4 VAL B 380
VAL B 254
ILE B 298
PHE B 302
 None
 1.00A 5jw1B-1mhyB:
undetectable		 5jw1B-1mhyB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mkp PYST1

(Homo sapiens) 		PF00782
(DSPc) 		4 VAL A 323
VAL A 291
SER A 300
ILE A 260
 None
 0.99A 5jw1B-1mkpA:
undetectable		 5jw1B-1mkpA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC

(Klebsiella
pneumoniae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 148
VAL A  26
ILE A  52
PHE A  30
 None
 0.75A 5jw1B-1ozhA:
0.0		 5jw1B-1ozhA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qon ACETYLCHOLINESTERASE

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 VAL A 304
SER A 306
ARG A  45
PHE A  44
 None
 1.02A 5jw1B-1qonA:
undetectable		 5jw1B-1qonA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs2 ADP-RIBOSYLTRANSFERA
SE

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		4 VAL A 442
ARG A 180
ILE A 182
PHE A 177
 None
 1.01A 5jw1B-1qs2A:
undetectable		 5jw1B-1qs2A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rvk ISOMERASE/LACTONIZIN
G ENZYME

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A   8
ARG A  12
ILE A 376
PHE A  11
 None
 0.93A 5jw1B-1rvkA:
undetectable		 5jw1B-1rvkA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukc ESTA

(Aspergillus
niger) 		PF00135
(COesterase) 		4 VAL A 328
VAL A 236
ILE A 447
PHE A 477
 None
 0.96A 5jw1B-1ukcA:
undetectable		 5jw1B-1ukcA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uqw PUTATIVE BINDING
PROTEIN YLIB

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 VAL A 421
VAL A 290
ARG A 263
ILE A 455
 None
 1.05A 5jw1B-1uqwA:
undetectable		 5jw1B-1uqwA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wod MODA

(Escherichia
coli) 		PF13531
(SBP_bac_11) 		4 VAL A 175
VAL A  88
ILE A 100
PHE A 186
 None
 1.00A 5jw1B-1wodA:
undetectable		 5jw1B-1wodA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1w TRICORN PROTEASE
INTERACTING FACTOR
F3

(Thermoplasma
acidophilum) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 VAL A 486
VAL A 447
ARG A 359
ILE A 361
 None
 0.88A 5jw1B-1z1wA:
1.0		 5jw1B-1z1wA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ztv HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF01904
(DUF72) 		4 VAL A  62
VAL A 165
SER A 163
ARG A 127
 None
 0.90A 5jw1B-1ztvA:
undetectable		 5jw1B-1ztvA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag1 BENZALDEHYDE LYASE

(Pseudomonas
fluorescens) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 142
VAL A  19
ILE A  45
PHE A  23
 None
 1.00A 5jw1B-2ag1A:
undetectable		 5jw1B-2ag1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eve HYPOTHETICAL PROTEIN
PSPTO5229

(Pseudomonas
syringae group
genomosp. 3) 		PF01878
(EVE) 		4 VAL A  66
VAL A 102
ILE A  59
PHE A  48
 None
 1.03A 5jw1B-2eveA:
undetectable		 5jw1B-2eveA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3n ALPHA-GLUCOSIDASE

(Sulfolobus
solfataricus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 VAL A 491
VAL A 206
ILE A 247
PHE A 210
 None
 1.09A 5jw1B-2g3nA:
undetectable		 5jw1B-2g3nA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE

(Escherichia
coli) 		PF00239
(Resolvase) 		4 VAL A 107
ARG A  91
ILE A  90
PHE A  92
 None
 0.95A 5jw1B-2gm5A:
undetectable		 5jw1B-2gm5A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 VAL A 178
VAL A 162
ARG A  98
ILE A 105
 None
 1.06A 5jw1B-2gsrA:
undetectable		 5jw1B-2gsrA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2haw MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Bacillus
subtilis) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 VAL A 302
VAL A 253
ILE A 238
PHE A 250
 None
 1.04A 5jw1B-2hawA:
undetectable		 5jw1B-2hawA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iph THIOL PROTEASE P3C

(Norwalk virus) 		PF05416
(Peptidase_C37) 		4 VAL A1153
ARG A1059
ILE A1047
PHE A1060
 None
 0.80A 5jw1B-2iphA:
undetectable		 5jw1B-2iphA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o56 PUTATIVE MANDELATE
RACEMASE

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A 263
VAL A 248
ILE A 273
PHE A 282
 None
 0.93A 5jw1B-2o56A:
0.0		 5jw1B-2o56A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o9a ACETATE OPERON
REPRESSOR

(Escherichia
coli) 		PF01614
(IclR) 		4 VAL A 172
VAL A  26
ILE A 153
PHE A 161
 None
 1.07A 5jw1B-2o9aA:
undetectable		 5jw1B-2o9aA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjp SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR

(Escherichia
coli) 		PF09107
(SelB-wing_3) 		4 VAL A 578
ARG A 546
ILE A 536
PHE A 502
 None
 0.97A 5jw1B-2pjpA:
undetectable		 5jw1B-2pjpA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qo3 ERYAII ERYTHROMYCIN
POLYKETIDE SYNTHASE
MODULES 3 AND 4

(Saccharopolyspora
erythraea) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 VAL A 749
VAL A 722
SER A 724
PHE A 733
 None
 0.95A 5jw1B-2qo3A:
undetectable		 5jw1B-2qo3A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v26 MYOSIN VI

(Sus scrofa) 		PF00063
(Myosin_head) 		4 VAL A 164
SER A 664
ILE A 488
PHE A 484
 None
 0.90A 5jw1B-2v26A:
undetectable		 5jw1B-2v26A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x30 PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
coelicolor) 		PF00977
(His_biosynth) 		4 VAL A  52
VAL A 164
SER A 196
ILE A 208
 None
None
SO4  A1242 ( 4.8A)
None
 0.90A 5jw1B-2x30A:
undetectable		 5jw1B-2x30A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xro HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGV

(Pseudomonas
putida) 		PF01614
(IclR)
PF09339
(HTH_IclR) 		4 VAL A 140
VAL A 223
SER A 109
ILE A 124
 None
 1.09A 5jw1B-2xroA:
undetectable		 5jw1B-2xroA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y89 PHOSPHORIBOSYL
ISOMERASE A

(Mycobacterium
tuberculosis) 		PF00977
(His_biosynth) 		4 VAL A  52
VAL A 168
SER A 200
ILE A 212
 None
 0.83A 5jw1B-2y89A:
undetectable		 5jw1B-2y89A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyt OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Geobacillus
kaustophilus) 		PF00215
(OMPdecase) 		4 VAL A  81
VAL A  86
ILE A   8
PHE A  32
 None
 1.06A 5jw1B-2yytA:
undetectable		 5jw1B-2yytA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddu PROLYL ENDOPEPTIDASE

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 VAL A 455
VAL A 379
SER A 400
ILE A 382
 ACT  A 802 ( 4.3A)
None
None
None
 1.09A 5jw1B-3dduA:
undetectable		 5jw1B-3dduA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh4 SODIUM/GLUCOSE
COTRANSPORTER

(Vibrio
parahaemolyticus) 		PF00474
(SSF) 		4 VAL A 460
VAL A 132
ILE A 139
PHE A 140
 None
 0.87A 5jw1B-3dh4A:
undetectable		 5jw1B-3dh4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1

(Arabidopsis
thaliana;
Escherichia
coli) 		PF00400
(WD40)
PF01547
(SBP_bac_1) 		4 SER A1122
ARG A1157
ILE A1167
PHE A1158
 None
 0.90A 5jw1B-3dm0A:
undetectable		 5jw1B-3dm0A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwq D-SERINE DEAMINASE

(Paraburkholderia
xenovorans) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 VAL A 410
ARG A  87
ILE A  97
PHE A  86
 None
GOL  A 426 (-3.6A)
None
None
 1.08A 5jw1B-3gwqA:
undetectable		 5jw1B-3gwqA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hcz POSSIBLE
THIOL-DISULFIDE
ISOMERASE

(Cytophaga
hutchinsonii) 		PF00578
(AhpC-TSA) 		4 VAL A 355
VAL A 420
ILE A 398
PHE A 429
 None
 1.06A 5jw1B-3hczA:
undetectable		 5jw1B-3hczA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hfq UNCHARACTERIZED
PROTEIN LP_2219

(Lactobacillus
plantarum) 		PF10282
(Lactonase) 		4 VAL A 302
ARG A 338
ILE A   5
PHE A 339
 None
 0.93A 5jw1B-3hfqA:
undetectable		 5jw1B-3hfqA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhg TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Neisseria
meningitidis) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 VAL A 127
SER A 125
ARG A 281
PHE A 285
 None
 1.08A 5jw1B-3hhgA:
undetectable		 5jw1B-3hhgA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i27 HEMAGGLUTININ-ESTERA
SE

(Bovine
torovirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 VAL A  81
SER A  37
ILE A  52
PHE A  60
 None
 1.05A 5jw1B-3i27A:
undetectable		 5jw1B-3i27A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihy PHOSPHATIDYLINOSITOL
3-KINASE CATALYTIC
SUBUNIT TYPE 3

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka) 		4 VAL A 381
SER A 481
ARG A 523
PHE A 524
 None
 0.98A 5jw1B-3ihyA:
undetectable		 5jw1B-3ihyA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2b GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A, CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL A  57
SER A  41
ILE A  30
PHE A   8
 None
 1.06A 5jw1B-3k2bA:
undetectable		 5jw1B-3k2bA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4w UNCHARACTERIZED
PROTEIN BB4693

(Bordetella
bronchiseptica) 		PF04909
(Amidohydro_2) 		5 VAL A 133
VAL A 184
SER A 186
ARG A   7
PHE A   6
 None
 1.24A 5jw1B-3k4wA:
undetectable		 5jw1B-3k4wA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V ALPHA CHAIN

(Escherichia
coli) 		PF13538
(UvrD_C_2)
PF13604
(AAA_30) 		4 VAL D 292
SER D 167
ILE D 313
PHE D 123
 None
 1.07A 5jw1B-3k70D:
undetectable		 5jw1B-3k70D:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ke6 PROTEIN
RV1364C/MT1410

(Mycobacterium
tuberculosis) 		PF07228
(SpoIIE)
PF13581
(HATPase_c_2) 		4 VAL A 450
VAL A 417
SER A 443
ILE A 438
 None
 0.99A 5jw1B-3ke6A:
undetectable		 5jw1B-3ke6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l09 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Jannaschia sp.
CCS1) 		PF07848
(PaaX) 		4 VAL A 172
SER A 221
ARG A 219
ILE A 217
 None
 0.98A 5jw1B-3l09A:
undetectable		 5jw1B-3l09A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lv4 GLYCOSIDE HYDROLASE
YXIA

(Bacillus
licheniformis) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		4 VAL A 362
VAL A 260
ILE A 227
PHE A 247
 None
 0.91A 5jw1B-3lv4A:
undetectable		 5jw1B-3lv4A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfn NAD KINASE

(Homo sapiens) 		PF01513
(NAD_kinase) 		4 VAL A 157
VAL A 109
ILE A 171
PHE A 164
 None
 1.06A 5jw1B-3pfnA:
undetectable		 5jw1B-3pfnA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnk PUTATIVE LIPOPROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 VAL A 108
VAL A 153
ARG A 531
ILE A 529
 None
 1.04A 5jw1B-3qnkA:
undetectable		 5jw1B-3qnkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage 201phi2-1) 		PF00091
(Tubulin) 		4 VAL A 208
VAL A 117
SER A 115
ILE A 172
 None
 1.08A 5jw1B-3r4vA:
undetectable		 5jw1B-3r4vA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rfy PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYP38, CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00160
(Pro_isomerase) 		4 VAL A 295
VAL A  93
ARG A 290
ILE A 288
 None
 1.03A 5jw1B-3rfyA:
undetectable		 5jw1B-3rfyA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s8d COENZYME A
TRANSFERASE

(Yersinia pestis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 VAL A 302
ARG A 353
ILE A 311
PHE A 351
 None
 1.05A 5jw1B-3s8dA:
undetectable		 5jw1B-3s8dA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8l ADENINE DEAMINASE 2

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1)
PF13382
(Adenine_deam_C) 		4 VAL A 109
VAL A 291
SER A  98
PHE A 538
 None
 0.94A 5jw1B-3t8lA:
0.0		 5jw1B-3t8lA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqh QUINONE
OXIDOREDUCTASE

(Coxiella
burnetii) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		4 VAL A 314
VAL A  37
SER A  73
ILE A 116
 None
 1.01A 5jw1B-3tqhA:
undetectable		 5jw1B-3tqhA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tzw POLYKETIDE SYNTHASE
PKS13

(Mycobacterium
tuberculosis) 		PF00698
(Acyl_transf_1) 		4 VAL A 940
SER A 807
ILE A 781
PHE A 777
 None
 1.09A 5jw1B-3tzwA:
undetectable		 5jw1B-3tzwA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CMR4

(Archaeoglobus
fulgidus) 		PF03787
(RAMPs) 		4 VAL C  19
VAL C  53
ILE C 295
PHE C  11
 None
G  I   8 ( 4.3A)
None
None
 0.98A 5jw1B-3x1lC:
undetectable		 5jw1B-3x1lC:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Sus scrofa) 		PF00063
(Myosin_head)
PF01353
(GFP) 		4 VAL A 164
SER A 664
ILE A 488
PHE A 484
 None
 0.89A 5jw1B-4anjA:
undetectable		 5jw1B-4anjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cyf PANTETHEINASE

(Homo sapiens) 		PF00795
(CN_hydrolase) 		4 VAL A 248
SER A 252
ILE A 214
PHE A 234
 None
None
CSO  A 211 ( 3.9A)
CSO  A 211 ( 4.0A)
 0.99A 5jw1B-4cyfA:
undetectable		 5jw1B-4cyfA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d6v G PROTEIN BETA
SUBUNIT GIB2

(Cryptococcus
neoformans) 		PF00400
(WD40) 		4 SER A 122
ARG A 155
ILE A 165
PHE A 156
 None
 0.90A 5jw1B-4d6vA:
undetectable		 5jw1B-4d6vA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h14 SPIKE GLYCOPROTEIN

(Betacoronavirus
1) 		PF16451
(Spike_NTD) 		4 VAL A 191
VAL A 139
SER A 137
PHE A 219
 None
 1.08A 5jw1B-4h14A:
undetectable		 5jw1B-4h14A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifa EXTRACELLULAR
PROTEIN CONTAINING A
SCP DOMAIN

(Bacillus
anthracis) 		PF00188
(CAP)
PF14504
(CAP_assoc_N) 		4 VAL A 130
VAL A 185
ARG A 239
ILE A 235
 None
None
TRS  A 406 (-3.1A)
None
 0.80A 5jw1B-4ifaA:
undetectable		 5jw1B-4ifaA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 VAL A 479
VAL A 474
SER A 487
ILE A 456
 None
 1.07A 5jw1B-4iugA:
undetectable		 5jw1B-4iugA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lct COP9 SIGNALOSOME
COMPLEX SUBUNIT 1

(Arabidopsis
thaliana) 		PF01399
(PCI)
PF10602
(RPN7) 		4 VAL A 252
VAL A 195
ILE A 163
PHE A 159
 None
 1.07A 5jw1B-4lctA:
undetectable		 5jw1B-4lctA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lhb MOLYBDOPTERIN
ADENYLYLTRANSFERASE

(Pyrococcus
furiosus) 		PF00994
(MoCF_biosynth) 		4 VAL A  61
VAL A 139
SER A 141
ILE A 156
 None
 1.05A 5jw1B-4lhbA:
undetectable		 5jw1B-4lhbA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp2 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CYSB

(Salmonella
enterica) 		PF03466
(LysR_substrate) 		4 VAL B 171
SER B 169
ILE B 264
PHE B 265
 None
 1.03A 5jw1B-4lp2B:
undetectable		 5jw1B-4lp2B:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 VAL A 282
SER A 258
ILE A 276
PHE A 261
 None
 0.98A 5jw1B-4m7eA:
undetectable		 5jw1B-4m7eA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1s V-TYPE ATP SYNTHASE
ALPHA CHAIN

(Thermoplasma
volcanium) 		PF14890
(Intein_splicing) 		4 VAL A  58
VAL A 151
SER A  65
ILE A  52
 None
 1.08A 5jw1B-4o1sA:
undetectable		 5jw1B-4o1sA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oya ADENYLATE CYCLASE
TYPE 10

(Homo sapiens) 		PF00211
(Guanylate_cyc) 		4 VAL A 167
ARG A  33
ILE A 314
PHE A 157
 1VE  A 501 (-3.7A)
None
None
None
 1.05A 5jw1B-4oyaA:
undetectable		 5jw1B-4oyaA:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2

(Mus musculus) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		6 VAL A 117
VAL A 350
SER A 354
ARG A 514
ILE A 518
PHE A 519
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
None
None
None
None
 0.30A 5jw1B-4ph9A:
62.7		 5jw1B-4ph9A:
99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psm SSDNA BINDING
PROTEIN

(Pyrococcus
furiosus) 		PF10015
(DUF2258) 		4 VAL A   9
VAL A  21
ILE A  74
PHE A  67
 None
 1.04A 5jw1B-4psmA:
undetectable		 5jw1B-4psmA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP

(Salmonella
enterica) 		PF12468
(TTSSLRR)
PF14496
(NEL) 		4 VAL A 550
VAL A 599
ILE A 639
PHE A 614
 None
 1.07A 5jw1B-4pufA:
undetectable		 5jw1B-4pufA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 152
VAL A  30
ILE A  56
PHE A  34
 None
 0.87A 5jw1B-4rjkA:
undetectable		 5jw1B-4rjkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tw0 SCAVENGER RECEPTOR
CLASS B MEMBER 2

(Homo sapiens) 		PF01130
(CD36) 		4 VAL A 173
VAL A 408
ILE A  75
PHE A 168
 None
 1.04A 5jw1B-4tw0A:
undetectable		 5jw1B-4tw0A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u28 PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
sviceus) 		PF00977
(His_biosynth) 		4 VAL A  56
VAL A 168
SER A 200
ILE A 212
 None
None
PO4  A 301 ( 4.4A)
None
 0.85A 5jw1B-4u28A:
undetectable		 5jw1B-4u28A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wwv AMINOPEPTIDASE FROM
FAMILY M42

(Desulfurococcus
amylolyticus) 		PF05343
(Peptidase_M42) 		4 VAL A 106
SER A  18
ARG A 186
ILE A  13
 None
 1.08A 5jw1B-4wwvA:
undetectable		 5jw1B-4wwvA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xdt FAD:PROTEIN FMN
TRANSFERASE

(Treponema
pallidum) 		PF02424
(ApbE) 		4 VAL A 229
SER A 231
ILE A 325
PHE A 276
 None
None
EDO  A 410 ( 4.4A)
None
 0.95A 5jw1B-4xdtA:
undetectable		 5jw1B-4xdtA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y18 BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN

(Homo sapiens) 		PF00533
(BRCT) 		4 VAL A1833
SER A1841
ARG A1699
ILE A1707
 None
 0.97A 5jw1B-4y18A:
undetectable		 5jw1B-4y18A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwj CHIMERA PROTEIN OF
HUMAN RHODOPSIN,
MOUSE S-ARRESTIN,
AND T4 ENDOLYSIN

(Escherichia
virus T4;
Homo sapiens;
Mus musculus) 		PF00001
(7tm_1)
PF00339
(Arrestin_N)
PF00959
(Phage_lysozyme)
PF02752
(Arrestin_C)
PF10413
(Rhodopsin_N) 		4 VAL A 157
SER A 127
ARG A 135
ILE A 133
 None
 0.98A 5jw1B-4zwjA:
undetectable		 5jw1B-4zwjA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b6k UNCHARACTERIZED
PROTEIN CGKR1

([Candida]
glabrata) 		PF01370
(Epimerase) 		4 VAL A 207
SER A 134
ARG A 272
ILE A 204
 None
 1.08A 5jw1B-5b6kA:
undetectable		 5jw1B-5b6kA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5far 7,8-DIHYDRONEOPTERIN
ALDOLASE

(Bacillus cereus) 		PF02152
(FolB) 		4 VAL A  72
SER A  74
ARG A 117
ILE A  79
 None
 0.93A 5jw1B-5farA:
undetectable		 5jw1B-5farA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h08 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 VAL A1931
VAL A1945
SER A1948
ILE A1953
 None
 1.08A 5jw1B-5h08A:
undetectable		 5jw1B-5h08A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9d HEPTAPRENYL
DIPHOSPHATE SYNTHASE
(HEPPP SYNTHASE)
SUBUNIT 1 FAMILY
PROTEIN

(Staphylococcus
aureus) 		PF07307
(HEPPP_synt_1) 		4 VAL C 102
SER C  98
ILE C  51
PHE C 132
 None
 0.94A 5jw1B-5h9dC:
undetectable		 5jw1B-5h9dC:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihr PROBABLE
BETA-GALACTOSIDASE A

(Aspergillus
niger) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 VAL A 479
VAL A 474
SER A 487
ILE A 456
 None
 1.05A 5jw1B-5ihrA:
undetectable		 5jw1B-5ihrA:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2

(Homo sapiens) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		6 VAL A 116
VAL A 349
SER A 353
ARG A 513
ILE A 517
PHE A 518
 None
ID8  A 601 (-3.9A)
ID8  A 601 ( 4.7A)
None
None
None
 0.35A 5jw1B-5ikrA:
61.1		 5jw1B-5ikrA:
87.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lon KLLA0E01827P

(Kluyveromyces
lactis) 		PF06058
(DCP1) 		4 VAL B  17
VAL B  53
ILE B 171
PHE B  30
 None
 1.02A 5jw1B-5lonB:
undetectable		 5jw1B-5lonB:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyd CELLULASE, PUTATIVE,
CEL5D

(Cellvibrio
japonicus) 		no annotation 4 VAL A 192
VAL A 164
ILE A 444
PHE A 445
 None
 1.05A 5jw1B-5oydA:
undetectable		 5jw1B-5oydA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szr PROTEIN PCDHGB2

(Mus musculus) 		PF00028
(Cadherin) 		4 VAL A 258
VAL A 289
SER A 302
PHE A 217
 None
 1.05A 5jw1B-5szrA:
undetectable		 5jw1B-5szrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xh9 EXTRACELLULAR
INVERTASE

(Aspergillus
kawachii) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 588
SER A 590
ARG A 533
ILE A 538
 None
 1.04A 5jw1B-5xh9A:
undetectable		 5jw1B-5xh9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xni MCYF

(Microcystis
aeruginosa) 		no annotation 4 VAL A  18
VAL A  10
ILE A 230
PHE A 226
 None
 0.95A 5jw1B-5xniA:
undetectable		 5jw1B-5xniA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs VP2

(Aquareovirus C) 		no annotation 4 VAL 2 398
SER 2 684
ARG 2 666
PHE 2 681
 None
 0.97A 5jw1B-5zvs2:
undetectable		 5jw1B-5zvs2:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 4 VAL A 387
VAL A 477
SER A 479
ILE A 491
 None
 1.03A 5jw1B-6etzA:
undetectable		 5jw1B-6etzA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fk6 RHODOPSIN

(Bos taurus) 		no annotation 4 VAL A 157
SER A 127
ARG A 135
ILE A 133
 None
 1.07A 5jw1B-6fk6A:
undetectable		 5jw1B-6fk6A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g8r NUCLEAR BODY PROTEIN
SP140

(Homo sapiens) 		no annotation 4 VAL B 857
ARG B 824
ILE B 826
PHE B 827
 None
 1.01A 5jw1B-6g8rB:
undetectable		 5jw1B-6g8rB:
8.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gct NEUTRAL AMINO ACID
TRANSPORTER B(0)

(Homo sapiens) 		no annotation 4 VAL A 270
SER A 111
ILE A 113
PHE A 259
 None
 1.04A 5jw1B-6gctA:
undetectable		 5jw1B-6gctA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gng -

(-) 		no annotation 4 VAL A 529
VAL A 166
ARG A  99
ILE A  59
 None
 1.08A 5jw1B-6gngA:
0.0		 5jw1B-6gngA:
undetectable