SIMILAR PATTERNS OF AMINO ACIDS FOR 5JW1_A_CELA602_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN


(Homo sapiens)
PF07686
(V-set)
PF08205
(C2-set_2)
4 VAL A 100
LEU A  65
SER A  66
ILE A  61
None
0.95A 5jw1A-1dr9A:
0.0
5jw1A-1dr9A:
15.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE


(Ovis aries)
PF00008
(EGF)
PF03098
(An_peroxidase)
4 VAL A 116
LEU A 352
SER A 353
ILE A 517
None
SCL  A 700 ( 4.8A)
None
None
0.28A 5jw1A-1ebvA:
57.4
5jw1A-1ebvA:
64.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1es6 MATRIX PROTEIN VP40

(Ebola virus sp.)
PF07447
(VP40)
4 VAL A 162
SER A 316
ARG A 214
ILE A 216
None
0.95A 5jw1A-1es6A:
0.0
5jw1A-1es6A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyp CHALCONE-FLAVONONE
ISOMERASE 1


(Medicago sativa)
PF02431
(Chalcone)
4 VAL A 121
LEU A 188
SER A 185
ILE A  93
None
0.90A 5jw1A-1eypA:
0.0
5jw1A-1eypA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnz GSI-B4 ISOLECTIN

(Griffonia
simplicifolia)
PF00139
(Lectin_legB)
4 VAL A 124
LEU A  90
SER A 217
ILE A 230
None
1.04A 5jw1A-1gnzA:
undetectable
5jw1A-1gnzA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hlg LIPASE, GASTRIC

(Homo sapiens)
PF00561
(Abhydrolase_1)
4 LEU A 169
SER A 168
ILE A 173
PHE A 163
None
0.94A 5jw1A-1hlgA:
0.0
5jw1A-1hlgA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyg L-LACTATE/MALATE
DEHYDROGENASE


(Methanocaldococcus
jannaschii)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 LEU A 186
SER A 187
ILE A 196
PHE A 202
None
1.04A 5jw1A-1hygA:
0.0
5jw1A-1hygA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqk CARBON MONOXIDE
DEHYDROGENASE


(Rhodospirillum
rubrum)
PF03063
(Prismane)
4 VAL A 134
LEU A 229
ILE A 190
PHE A 156
None
0.94A 5jw1A-1jqkA:
0.0
5jw1A-1jqkA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kij DNA GYRASE SUBUNIT B

(Thermus
thermophilus)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
4 VAL A 168
LEU A 125
ILE A 176
PHE A 177
None
0.96A 5jw1A-1kijA:
0.0
5jw1A-1kijA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lw3 MYOTUBULARIN-RELATED
PROTEIN 2


(Homo sapiens)
PF02893
(GRAM)
PF06602
(Myotub-related)
4 VAL A 258
LEU A 270
ARG A 226
ILE A 220
None
1.01A 5jw1A-1lw3A:
undetectable
5jw1A-1lw3A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mkx PRETHROMBIN-2

(Bos taurus)
PF00089
(Trypsin)
PF09396
(Thrombin_light)
4 VAL K 231
LEU K  46
SER K  45
ILE K  68
None
0.80A 5jw1A-1mkxK:
undetectable
5jw1A-1mkxK:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8y PROTOONCOPROTEIN

(Rattus
norvegicus)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV)
4 VAL C 293
LEU C 324
SER C 352
ILE C 335
None
1.01A 5jw1A-1n8yC:
undetectable
5jw1A-1n8yC:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnw HYPOTHETICAL PROTEIN

(Pyrococcus
furiosus)
no annotation 4 VAL A 134
LEU A 209
ILE A 220
PHE A 207
None
0.83A 5jw1A-1nnwA:
undetectable
5jw1A-1nnwA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd2 HEMATOPOIETIC
PROSTAGLANDIN D
SYNTHASE


(Rattus
norvegicus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 VAL 1  92
LEU 1  71
ILE 1  27
PHE 1  22
None
0.63A 5jw1A-1pd21:
undetectable
5jw1A-1pd21:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3i GLUTATHIONE
S-TRANSFERASE 28 KDA


(Schistosoma
mansoni)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 VAL A   8
LEU A 161
SER A  19
ILE A 164
None
1.05A 5jw1A-1u3iA:
undetectable
5jw1A-1u3iA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6z EXOPOLYPHOSPHATASE

(Escherichia
coli)
PF02541
(Ppx-GppA)
4 VAL A 270
LEU A  47
SER A  20
PHE A  23
None
None
SO4  A 701 (-3.0A)
None
0.97A 5jw1A-1u6zA:
undetectable
5jw1A-1u6zA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE


(Homo sapiens)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 VAL A  88
LEU A  71
ILE A  27
PHE A  22
None
0.99A 5jw1A-1v40A:
undetectable
5jw1A-1v40A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE


(Homo sapiens)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 VAL A  92
LEU A  71
ILE A  27
PHE A  22
None
0.65A 5jw1A-1v40A:
undetectable
5jw1A-1v40A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmb IAA-AMINO ACID
HYDROLASE HOMOLOG 2


(Arabidopsis
thaliana)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
4 VAL A 364
LEU A 198
SER A 199
ILE A 403
None
0.92A 5jw1A-1xmbA:
undetectable
5jw1A-1xmbA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zos 5'-METHYLTHIOADENOSI
NE /
S-ADENOSYLHOMOCYSTEI
NE NUCLEOSIDASE


(Streptococcus
pneumoniae)
PF01048
(PNP_UDP_1)
4 VAL A  59
LEU A 190
ARG A 193
ILE A  91
None
None
MTM  A 301 (-3.2A)
None
0.98A 5jw1A-1zosA:
undetectable
5jw1A-1zosA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buj SERINE/THREONINE-PRO
TEIN KINASE 16


(Homo sapiens)
PF00069
(Pkinase)
4 VAL A 249
LEU A 221
SER A 220
ILE A 132
None
0.96A 5jw1A-2bujA:
undetectable
5jw1A-2bujA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fh5 SIGNAL RECOGNITION
PARTICLE RECEPTOR
ALPHA SUBUNIT


(Homo sapiens)
PF04086
(SRP-alpha_N)
4 LEU A  64
SER A   9
ILE A   7
PHE A  66
None
1.07A 5jw1A-2fh5A:
undetectable
5jw1A-2fh5A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inr DNA TOPOISOMERASE 4
SUBUNIT A


(Staphylococcus
aureus)
PF00521
(DNA_topoisoIV)
4 VAL A 165
LEU A 156
SER A 158
ILE A 135
None
0.89A 5jw1A-2inrA:
1.5
5jw1A-2inrA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iph THIOL PROTEASE P3C

(Norwalk virus)
PF05416
(Peptidase_C37)
4 VAL A1153
ARG A1059
ILE A1047
PHE A1060
None
0.90A 5jw1A-2iphA:
undetectable
5jw1A-2iphA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j04 YDR362CP

(Saccharomyces
cerevisiae)
no annotation 4 VAL B 226
LEU B 384
SER B 385
ILE B 341
None
1.06A 5jw1A-2j04B:
undetectable
5jw1A-2j04B:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq4 IRON-SULFUR CLUSTER
BIOSYNTHESIS PROTEIN
ISCU


(Thermus
thermophilus)
PF01592
(NifU_N)
4 VAL A  43
LEU A  73
SER A  70
ILE A  11
None
1.00A 5jw1A-2qq4A:
undetectable
5jw1A-2qq4A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN


(Salmonella
enterica)
PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA)
4 VAL A 317
LEU A 253
SER A 254
ARG A 296
None
1.04A 5jw1A-2qzaA:
undetectable
5jw1A-2qzaA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v26 MYOSIN VI

(Sus scrofa)
PF00063
(Myosin_head)
4 VAL A 164
SER A 664
ILE A 488
PHE A 484
None
0.87A 5jw1A-2v26A:
undetectable
5jw1A-2v26A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhf UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE CYLD


(Homo sapiens)
PF00443
(UCH)
4 VAL A 696
LEU A 752
ILE A 777
PHE A 745
None
0.83A 5jw1A-2vhfA:
undetectable
5jw1A-2vhfA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmh FUCOLECTIN-RELATED
PROTEIN


(Streptococcus
pneumoniae)
PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C)
4 VAL A 574
LEU A 468
SER A 467
ILE A 441
None
0.94A 5jw1A-2wmhA:
undetectable
5jw1A-2wmhA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yq1 ORF73

(Murid
gammaherpesvirus
4)
no annotation 4 VAL A 234
LEU A 195
SER A 196
PHE A 168
None
0.98A 5jw1A-2yq1A:
undetectable
5jw1A-2yq1A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0l EARLY ANTIGEN
PROTEIN D


(Human
gammaherpesvirus
4)
PF04929
(Herpes_DNAp_acc)
4 VAL A 226
LEU A 265
ILE A 273
PHE A 267
None
0.95A 5jw1A-2z0lA:
undetectable
5jw1A-2z0lA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuk ALPHA-AMINO-EPSILON-
CAPROLACTAM RACEMASE


(Achromobacter
obae)
PF00202
(Aminotran_3)
4 VAL A 388
LEU A  45
SER A  46
ILE A 403
None
0.97A 5jw1A-2zukA:
undetectable
5jw1A-2zukA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzg ALANYL-TRNA
SYNTHETASE


(Pyrococcus
horikoshii)
PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD)
4 VAL A 675
LEU A 619
ARG A 625
ILE A 661
None
0.80A 5jw1A-2zzgA:
undetectable
5jw1A-2zzgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE


(Mycobacterium
tuberculosis)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 VAL A 420
LEU A 261
SER A 260
ILE A 265
None
None
NAD  A 550 ( 4.9A)
None
1.06A 5jw1A-3ce6A:
undetectable
5jw1A-3ce6A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE


(Mus musculus)
PF00004
(AAA)
PF09336
(Vps4_C)
4 VAL A 493
LEU A 574
ILE A 542
PHE A 576
None
0.68A 5jw1A-3cf0A:
undetectable
5jw1A-3cf0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cg1 UPF0100 PROTEIN
PF0080


(Pyrococcus
furiosus)
PF13531
(SBP_bac_11)
4 LEU A 167
SER A 166
ILE A 186
PHE A 182
None
0.98A 5jw1A-3cg1A:
undetectable
5jw1A-3cg1A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED


(Myxococcus
xanthus)
PF00204
(DNA_gyraseB)
4 LEU A 107
SER A 108
ILE A 162
PHE A 163
None
0.96A 5jw1A-3cwvA:
undetectable
5jw1A-3cwvA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1


(Arabidopsis
thaliana;
Escherichia
coli)
PF00400
(WD40)
PF01547
(SBP_bac_1)
4 SER A1122
ARG A1157
ILE A1167
PHE A1158
None
1.04A 5jw1A-3dm0A:
undetectable
5jw1A-3dm0A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3p PROTEIN KINASE,
PUTATIVE GLYCOGEN
SYNTHASE KINASE


(Leishmania
major)
PF00069
(Pkinase)
4 LEU A 243
ARG A 241
ILE A 239
PHE A 227
None
0.89A 5jw1A-3e3pA:
undetectable
5jw1A-3e3pA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnr ARGINYL-TRNA
SYNTHETASE


(Campylobacter
jejuni)
PF00750
(tRNA-synt_1d)
PF05746
(DALR_1)
4 LEU A 351
SER A 350
ARG A 125
ILE A 121
None
0.91A 5jw1A-3fnrA:
undetectable
5jw1A-3fnrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ha9 UNCHARACTERIZED
THIOREDOXIN-LIKE
PROTEIN


(Aeropyrum
pernix)
PF00578
(AhpC-TSA)
4 VAL A 183
LEU A  67
ILE A  99
PHE A  69
None
0.93A 5jw1A-3ha9A:
undetectable
5jw1A-3ha9A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN


(Saccharomyces
cerevisiae)
PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF08938
(HBS1_N)
4 LEU 1 436
SER 1 435
ILE 1 430
PHE 1 401
None
1.01A 5jw1A-3izq1:
undetectable
5jw1A-3izq1:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4w UNCHARACTERIZED
PROTEIN BB4693


(Bordetella
bronchiseptica)
PF04909
(Amidohydro_2)
4 VAL A 133
SER A 186
ARG A   7
PHE A   6
None
1.07A 5jw1A-3k4wA:
undetectable
5jw1A-3k4wA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khs PURINE NUCLEOSIDE
PHOSPHORYLASE


(Singapore
grouper
iridovirus)
PF01048
(PNP_UDP_1)
4 LEU A  65
SER A  64
ILE A  50
PHE A  53
None
0.70A 5jw1A-3khsA:
undetectable
5jw1A-3khsA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpz GET4 (YOR164C
HOMOLOG)


(Chaetomium
thermophilum)
PF04190
(DUF410)
4 VAL A 106
LEU A  74
ARG A  79
PHE A  78
None
0.88A 5jw1A-3lpzA:
undetectable
5jw1A-3lpzA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgx PUTATIVE P450
MONOOXYGENASE


(Amycolatopsis
balhimycina)
PF00067
(p450)
4 VAL A  89
LEU A 233
ILE A 191
PHE A 195
None
1.03A 5jw1A-3mgxA:
undetectable
5jw1A-3mgxA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnk PUTATIVE LIPOPROTEIN

(Bacteroides
fragilis)
PF07980
(SusD_RagB)
PF14322
(SusD-like_3)
4 VAL A 507
LEU A 304
ILE A 469
PHE A 308
None
0.88A 5jw1A-3qnkA:
undetectable
5jw1A-3qnkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rui UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7


(Saccharomyces
cerevisiae)
PF00899
(ThiF)
4 VAL A 437
LEU A 448
SER A 447
ILE A 452
None
0.99A 5jw1A-3ruiA:
undetectable
5jw1A-3ruiA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stt METHYLKETONE
SYNTHASE I


(Solanum
habrochaites)
PF12697
(Abhydrolase_6)
4 VAL A 208
LEU A 258
SER A 259
PHE A 254
None
0.90A 5jw1A-3sttA:
undetectable
5jw1A-3sttA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfw PUTATIVE
O-METHYLTRANSFERASE


(Klebsiella
pneumoniae)
PF01596
(Methyltransf_3)
4 VAL A 111
LEU A  53
ILE A 165
PHE A 139
None
0.89A 5jw1A-3tfwA:
undetectable
5jw1A-3tfwA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vh1 UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7


(Saccharomyces
cerevisiae)
PF00899
(ThiF)
PF16420
(ATG7_N)
4 VAL A 437
LEU A 448
SER A 447
ILE A 452
None
0.82A 5jw1A-3vh1A:
undetectable
5jw1A-3vh1A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9v PHOSPHATE-BINDING
PROTEIN


(unidentified
prokaryotic
organism)
PF12849
(PBP_like_2)
4 VAL A 368
LEU A  83
SER A 304
ILE A 302
None
0.98A 5jw1A-3w9vA:
undetectable
5jw1A-3w9vA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxf UNCHARACTERIZED
PROTEIN


(Danio rerio)
PF00443
(UCH)
4 VAL A 691
LEU A 747
ILE A 772
PHE A 740
None
0.82A 5jw1A-3wxfA:
undetectable
5jw1A-3wxfA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wyf GSP1P

(Saccharomyces
cerevisiae)
PF00071
(Ras)
4 VAL A  10
LEU A  52
SER A  53
PHE A 163
None
0.86A 5jw1A-3wyfA:
undetectable
5jw1A-3wyfA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE


(Parageobacillus
thermoglucosidasius)
PF00465
(Fe-ADH)
4 LEU A 858
SER A 856
ARG A 863
ILE A 861
None
1.03A 5jw1A-3zdrA:
undetectable
5jw1A-3zdrA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN


(Aequorea
victoria;
Sus scrofa)
PF00063
(Myosin_head)
PF01353
(GFP)
4 VAL A 164
SER A 664
ILE A 488
PHE A 484
None
0.86A 5jw1A-4anjA:
undetectable
5jw1A-4anjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d6v G PROTEIN BETA
SUBUNIT GIB2


(Cryptococcus
neoformans)
PF00400
(WD40)
4 SER A 122
ARG A 155
ILE A 165
PHE A 156
None
1.00A 5jw1A-4d6vA:
undetectable
5jw1A-4d6vA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwm UNCHARACTERIZED
PROTEIN YEDD


(Klebsiella
pneumoniae)
PF13987
(YedD)
4 VAL A  74
LEU A  57
SER A  56
ILE A 107
None
0.88A 5jw1A-4hwmA:
undetectable
5jw1A-4hwmA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ir8 SEDOHEPTULOSE-1,7
BISPHOSPHATASE,
PUTATIVE


(Toxoplasma
gondii)
PF00316
(FBPase)
4 VAL A 177
LEU A 155
SER A 154
ILE A  30
None
1.06A 5jw1A-4ir8A:
undetectable
5jw1A-4ir8A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk1 TUBEROUS SCLEROSIS 1
PROTEIN HOMOLOG


(Schizosaccharomyces
pombe)
PF04388
(Hamartin)
4 VAL A 234
LEU A 190
SER A 191
ILE A 144
None
0.96A 5jw1A-4kk1A:
undetectable
5jw1A-4kk1A:
20.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2


(Mus musculus)
PF00008
(EGF)
PF03098
(An_peroxidase)
6 VAL A 117
LEU A 353
SER A 354
ARG A 514
ILE A 518
PHE A 519
BOG  A 604 (-3.9A)
IBP  A 601 ( 4.7A)
None
None
None
None
0.47A 5jw1A-4ph9A:
62.6
5jw1A-4ph9A:
99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phc HISTIDINE--TRNA
LIGASE, CYTOPLASMIC


(Homo sapiens)
PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His)
4 VAL A 249
LEU A 322
SER A 323
ILE A 216
None
1.04A 5jw1A-4phcA:
undetectable
5jw1A-4phcA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psm SSDNA BINDING
PROTEIN


(Pyrococcus
furiosus)
PF10015
(DUF2258)
4 VAL A   9
LEU A  22
ILE A  74
PHE A  67
None
1.07A 5jw1A-4psmA:
undetectable
5jw1A-4psmA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdk MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE


(Synechocystis
sp. PCC 6803)
PF07109
(Mg-por_mtran_C)
4 LEU A 162
SER A 163
ARG A 223
ILE A 198
None
1.01A 5jw1A-4qdkA:
undetectable
5jw1A-4qdkA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qg5 PUTATIVE
PHOSPHOGLUCOMUTASE


(Leishmania
major)
PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III)
4 VAL A 250
LEU A 115
ILE A 130
PHE A 128
None
0.97A 5jw1A-4qg5A:
undetectable
5jw1A-4qg5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlx NITROREDUCTASE
FAMILY PROTEIN


(Lactobacillus
plantarum)
PF00881
(Nitroreductase)
4 VAL A 100
SER A  55
ILE A  91
PHE A  58
None
1.05A 5jw1A-4qlxA:
undetectable
5jw1A-4qlxA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C


(Francisella
tularensis)
no annotation 4 LEU A 217
SER A 216
ILE A 130
PHE A 221
None
0.99A 5jw1A-4qvrA:
undetectable
5jw1A-4qvrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1


(Homo sapiens;
synthetic
construct)
PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9)
4 LEU A2644
SER A2645
ARG A2642
ILE A2640
None
1.05A 5jw1A-4rh7A:
undetectable
5jw1A-4rh7A:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sli INTRAMOLECULAR
TRANS-SIALIDASE


(Macrobdella
decora)
PF02973
(Sialidase)
PF13088
(BNR_2)
4 VAL A 724
LEU A 647
SER A 665
ILE A 617
None
1.03A 5jw1A-4sliA:
undetectable
5jw1A-4sliA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uf3 ANTIAPOPTOTIC
MEMBRANE PROTEIN


(Mule deerpox
virus)
PF11099
(M11L)
4 LEU A  92
SER A  89
ILE A 136
PHE A 132
None
1.02A 5jw1A-4uf3A:
undetectable
5jw1A-4uf3A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzf BAND 3 ANION
TRANSPORT PROTEIN


(Homo sapiens)
PF00955
(HCO3_cotransp)
4 VAL A 513
LEU A 382
ARG A 388
ILE A 386
None
1.03A 5jw1A-4yzfA:
undetectable
5jw1A-4yzfA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zem TRANSLATION
INITIATION FACTOR
EIF2B-LIKE
PROTEIN,TRANSLATION
INITIATION FACTOR
EIF2B-LIKE PROTEIN


(Chaetomium
thermophilum)
PF01008
(IF-2B)
4 VAL A 274
LEU A 222
ARG A 290
ILE A 288
None
1.00A 5jw1A-4zemA:
2.5
5jw1A-4zemA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a08 PROBABLE
MANNOSYLTRANSFERASE
KTR4


(Saccharomyces
cerevisiae)
PF01793
(Glyco_transf_15)
4 VAL A 119
LEU A 461
ILE A 452
PHE A 109
None
1.07A 5jw1A-5a08A:
undetectable
5jw1A-5a08A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT


(Saccharomonospora
viridis)
PF01497
(Peripla_BP_2)
4 VAL A 278
LEU A  64
ARG A  84
ILE A  62
None
0.91A 5jw1A-5cr9A:
undetectable
5jw1A-5cr9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d91 AF2299
PROTEIN,PHOSPHATIDYL
INOSITOL SYNTHASE


(Archaeoglobus
fulgidus;
Renibacterium
salmoninarum)
PF01066
(CDP-OH_P_transf)
4 VAL A 157
LEU A 125
SER A 126
ILE A 188
None
1.01A 5jw1A-5d91A:
0.6
5jw1A-5d91A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE


(Burkholderia
vietnamiensis)
PF02350
(Epimerase_2)
4 VAL A  93
LEU A 134
ARG A 122
ILE A 126
None
1.03A 5jw1A-5dldA:
undetectable
5jw1A-5dldA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f3y UNCONVENTIONAL
MYOSIN-VIIB


(Mus musculus)
PF00784
(MyTH4)
4 VAL A1072
LEU A1117
SER A1114
ILE A1134
None
1.00A 5jw1A-5f3yA:
1.4
5jw1A-5f3yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fno MANGANESE
LIPOXYGENASE


(Magnaporthe
oryzae)
PF00305
(Lipoxygenase)
4 VAL A 372
LEU A 398
SER A 396
ARG A 403
None
0.93A 5jw1A-5fnoA:
0.9
5jw1A-5fnoA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN


(Lachnoclostridium
phytofermentans)
PF17167
(Glyco_hydro_36)
4 LEU A 804
SER A 805
ILE A 793
PHE A 800
None
1.02A 5jw1A-5h42A:
undetectable
5jw1A-5h42A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hyp C4B-BINDING PROTEIN
ALPHA CHAIN


(Homo sapiens)
PF00084
(Sushi)
4 VAL A  38
LEU A  82
SER A  83
ILE A  88
None
0.84A 5jw1A-5hypA:
undetectable
5jw1A-5hypA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijb TOLL-LIKE RECEPTOR
4, VARIABLE
LYMPHOCYTE RECEPTOR
B CHIMERA


(Eptatretus
burgeri;
Mus musculus)
PF00560
(LRR_1)
PF11921
(DUF3439)
PF13855
(LRR_8)
4 LEU A 232
SER A 210
ILE A 214
PHE A 236
None
0.98A 5jw1A-5ijbA:
undetectable
5jw1A-5ijbA:
22.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2


(Homo sapiens)
PF00008
(EGF)
PF03098
(An_peroxidase)
5 LEU A 352
SER A 353
ARG A 513
ILE A 517
PHE A 518
ID8  A 601 (-4.1A)
ID8  A 601 ( 4.7A)
None
None
None
0.58A 5jw1A-5ikrA:
61.3
5jw1A-5ikrA:
87.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2


(Homo sapiens)
PF00008
(EGF)
PF03098
(An_peroxidase)
5 VAL A 116
SER A 353
ARG A 513
ILE A 517
PHE A 518
None
ID8  A 601 ( 4.7A)
None
None
None
0.28A 5jw1A-5ikrA:
61.3
5jw1A-5ikrA:
87.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy3 GENOME POLYPROTEIN

(Zika virus)
PF00948
(Flavi_NS1)
4 LEU A 321
ARG A 324
ILE A 275
PHE A 323
None
1.07A 5jw1A-5iy3A:
undetectable
5jw1A-5iy3A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l44 K-26 DIPEPTIDYL
CARBOXYPEPTIDASE


(Astrosporangium
hypotensionis)
PF01432
(Peptidase_M3)
4 VAL A  49
LEU A 105
ILE A 101
PHE A  38
None
1.06A 5jw1A-5l44A:
2.3
5jw1A-5l44A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE


(Chaetomium
thermophilum)
no annotation 4 VAL A 228
LEU A 241
SER A 240
ILE A 345
None
1.02A 5jw1A-5o82A:
undetectable
5jw1A-5o82A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1


(Saccharomyces
cerevisiae)
PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
4 VAL T3047
LEU T3086
SER T3083
ILE T3104
None
0.94A 5jw1A-5ojsT:
undetectable
5jw1A-5ojsT:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5


(Homo sapiens)
PF01663
(Phosphodiest)
4 LEU A  43
ARG A  39
ILE A 351
PHE A  38
None
0.93A 5jw1A-5vemA:
undetectable
5jw1A-5vemA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5veo ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5


(Mus musculus)
PF01663
(Phosphodiest)
4 LEU A  43
ARG A  39
ILE A 351
PHE A  38
None
0.96A 5jw1A-5veoA:
undetectable
5jw1A-5veoA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyw PYRUVATE CARBOXYLASE

(Lactococcus
lactis)
PF00289
(Biotin_carb_N)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
4 VAL A 515
LEU A 563
SER A 565
ILE A 556
None
1.06A 5jw1A-5vywA:
undetectable
5jw1A-5vywA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w6m HISTIDINE--TRNA
LIGASE, CYTOPLASMIC


(Homo sapiens)
no annotation 4 VAL A 249
LEU A 322
SER A 323
ILE A 216
None
0.84A 5jw1A-5w6mA:
undetectable
5jw1A-5w6mA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7q CONSENSUS ELONGATION
FACTOR


(synthetic
construct)
no annotation 4 LEU A 158
SER A 159
ARG A 124
ILE A 120
None
0.90A 5jw1A-5w7qA:
undetectable
5jw1A-5w7qA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6x MRNA CAPPING ENZYME
P5


(Rice dwarf
virus)
no annotation 4 VAL C 206
LEU C 277
SER C 278
ILE C 283
None
1.05A 5jw1A-5x6xC:
undetectable
5jw1A-5x6xC:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yc1 TNF
RECEPTOR-ASSOCIATED
FACTOR 4


(Homo sapiens)
no annotation 4 VAL A 309
LEU A 390
SER A 389
ILE A 440
None
0.86A 5jw1A-5yc1A:
undetectable
5jw1A-5yc1A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yud BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 1E


(Mus musculus)
no annotation 4 VAL A 468
LEU A 504
SER A 505
ILE A 509
None
1.06A 5jw1A-5yudA:
undetectable
5jw1A-5yudA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zct -

(-)
no annotation 4 VAL A 198
LEU A 242
ARG A  64
ILE A  94
None
0.97A 5jw1A-5zctA:
undetectable
5jw1A-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus)
no annotation 4 VAL A 461
LEU A 442
ILE A 735
PHE A 742
None
0.97A 5jw1A-6aunA:
undetectable
5jw1A-6aunA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eys -

(-)
no annotation 4 LEU B  66
ARG B 182
ILE B 167
PHE B 181
None
1.02A 5jw1A-6eysB:
undetectable
5jw1A-6eysB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g8r NUCLEAR BODY PROTEIN
SP140


(Homo sapiens)
no annotation 4 VAL B 857
ARG B 824
ILE B 826
PHE B 827
None
0.96A 5jw1A-6g8rB:
undetectable
5jw1A-6g8rB:
8.69