SIMILAR PATTERNS OF AMINO ACIDS FOR 5JW1_A_CELA602_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dr9 | T LYMPHOCYTEACTIVATION ANTIGEN (Homo sapiens) |
PF07686(V-set)PF08205(C2-set_2) | 4 | VAL A 100LEU A 65SER A 66ILE A 61 | None | 0.95A | 5jw1A-1dr9A:0.0 | 5jw1A-1dr9A:15.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 4 | VAL A 116LEU A 352SER A 353ILE A 517 | NoneSCL A 700 ( 4.8A)NoneNone | 0.28A | 5jw1A-1ebvA:57.4 | 5jw1A-1ebvA:64.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1es6 | MATRIX PROTEIN VP40 (Ebola virus sp.) |
PF07447(VP40) | 4 | VAL A 162SER A 316ARG A 214ILE A 216 | None | 0.95A | 5jw1A-1es6A:0.0 | 5jw1A-1es6A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eyp | CHALCONE-FLAVONONEISOMERASE 1 (Medicago sativa) |
PF02431(Chalcone) | 4 | VAL A 121LEU A 188SER A 185ILE A 93 | None | 0.90A | 5jw1A-1eypA:0.0 | 5jw1A-1eypA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnz | GSI-B4 ISOLECTIN (Griffoniasimplicifolia) |
PF00139(Lectin_legB) | 4 | VAL A 124LEU A 90SER A 217ILE A 230 | None | 1.04A | 5jw1A-1gnzA:undetectable | 5jw1A-1gnzA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hlg | LIPASE, GASTRIC (Homo sapiens) |
PF00561(Abhydrolase_1) | 4 | LEU A 169SER A 168ILE A 173PHE A 163 | None | 0.94A | 5jw1A-1hlgA:0.0 | 5jw1A-1hlgA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyg | L-LACTATE/MALATEDEHYDROGENASE (Methanocaldococcusjannaschii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 186SER A 187ILE A 196PHE A 202 | None | 1.04A | 5jw1A-1hygA:0.0 | 5jw1A-1hygA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqk | CARBON MONOXIDEDEHYDROGENASE (Rhodospirillumrubrum) |
PF03063(Prismane) | 4 | VAL A 134LEU A 229ILE A 190PHE A 156 | None | 0.94A | 5jw1A-1jqkA:0.0 | 5jw1A-1jqkA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kij | DNA GYRASE SUBUNIT B (Thermusthermophilus) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | VAL A 168LEU A 125ILE A 176PHE A 177 | None | 0.96A | 5jw1A-1kijA:0.0 | 5jw1A-1kijA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lw3 | MYOTUBULARIN-RELATEDPROTEIN 2 (Homo sapiens) |
PF02893(GRAM)PF06602(Myotub-related) | 4 | VAL A 258LEU A 270ARG A 226ILE A 220 | None | 1.01A | 5jw1A-1lw3A:undetectable | 5jw1A-1lw3A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mkx | PRETHROMBIN-2 (Bos taurus) |
PF00089(Trypsin)PF09396(Thrombin_light) | 4 | VAL K 231LEU K 46SER K 45ILE K 68 | None | 0.80A | 5jw1A-1mkxK:undetectable | 5jw1A-1mkxK:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n8y | PROTOONCOPROTEIN (Rattusnorvegicus) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 4 | VAL C 293LEU C 324SER C 352ILE C 335 | None | 1.01A | 5jw1A-1n8yC:undetectable | 5jw1A-1n8yC:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nnw | HYPOTHETICAL PROTEIN (Pyrococcusfuriosus) |
no annotation | 4 | VAL A 134LEU A 209ILE A 220PHE A 207 | None | 0.83A | 5jw1A-1nnwA:undetectable | 5jw1A-1nnwA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd2 | HEMATOPOIETICPROSTAGLANDIN DSYNTHASE (Rattusnorvegicus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | VAL 1 92LEU 1 71ILE 1 27PHE 1 22 | None | 0.63A | 5jw1A-1pd21:undetectable | 5jw1A-1pd21:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u3i | GLUTATHIONES-TRANSFERASE 28 KDA (Schistosomamansoni) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | VAL A 8LEU A 161SER A 19ILE A 164 | None | 1.05A | 5jw1A-1u3iA:undetectable | 5jw1A-1u3iA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6z | EXOPOLYPHOSPHATASE (Escherichiacoli) |
PF02541(Ppx-GppA) | 4 | VAL A 270LEU A 47SER A 20PHE A 23 | NoneNoneSO4 A 701 (-3.0A)None | 0.97A | 5jw1A-1u6zA:undetectable | 5jw1A-1u6zA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v40 | GLUTATHIONE-REQUIRING PROSTAGLANDIN DSYNTHASE (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | VAL A 88LEU A 71ILE A 27PHE A 22 | None | 0.99A | 5jw1A-1v40A:undetectable | 5jw1A-1v40A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v40 | GLUTATHIONE-REQUIRING PROSTAGLANDIN DSYNTHASE (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | VAL A 92LEU A 71ILE A 27PHE A 22 | None | 0.65A | 5jw1A-1v40A:undetectable | 5jw1A-1v40A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xmb | IAA-AMINO ACIDHYDROLASE HOMOLOG 2 (Arabidopsisthaliana) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | VAL A 364LEU A 198SER A 199ILE A 403 | None | 0.92A | 5jw1A-1xmbA:undetectable | 5jw1A-1xmbA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zos | 5'-METHYLTHIOADENOSINE /S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Streptococcuspneumoniae) |
PF01048(PNP_UDP_1) | 4 | VAL A 59LEU A 190ARG A 193ILE A 91 | NoneNoneMTM A 301 (-3.2A)None | 0.98A | 5jw1A-1zosA:undetectable | 5jw1A-1zosA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buj | SERINE/THREONINE-PROTEIN KINASE 16 (Homo sapiens) |
PF00069(Pkinase) | 4 | VAL A 249LEU A 221SER A 220ILE A 132 | None | 0.96A | 5jw1A-2bujA:undetectable | 5jw1A-2bujA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fh5 | SIGNAL RECOGNITIONPARTICLE RECEPTORALPHA SUBUNIT (Homo sapiens) |
PF04086(SRP-alpha_N) | 4 | LEU A 64SER A 9ILE A 7PHE A 66 | None | 1.07A | 5jw1A-2fh5A:undetectable | 5jw1A-2fh5A:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inr | DNA TOPOISOMERASE 4SUBUNIT A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV) | 4 | VAL A 165LEU A 156SER A 158ILE A 135 | None | 0.89A | 5jw1A-2inrA:1.5 | 5jw1A-2inrA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iph | THIOL PROTEASE P3C (Norwalk virus) |
PF05416(Peptidase_C37) | 4 | VAL A1153ARG A1059ILE A1047PHE A1060 | None | 0.90A | 5jw1A-2iphA:undetectable | 5jw1A-2iphA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j04 | YDR362CP (Saccharomycescerevisiae) |
no annotation | 4 | VAL B 226LEU B 384SER B 385ILE B 341 | None | 1.06A | 5jw1A-2j04B:undetectable | 5jw1A-2j04B:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qq4 | IRON-SULFUR CLUSTERBIOSYNTHESIS PROTEINISCU (Thermusthermophilus) |
PF01592(NifU_N) | 4 | VAL A 43LEU A 73SER A 70ILE A 11 | None | 1.00A | 5jw1A-2qq4A:undetectable | 5jw1A-2qq4A:13.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qza | SECRETED EFFECTORPROTEIN (Salmonellaenterica) |
PF13599(Pentapeptide_4)PF13979(SopA_C)PF13981(SopA) | 4 | VAL A 317LEU A 253SER A 254ARG A 296 | None | 1.04A | 5jw1A-2qzaA:undetectable | 5jw1A-2qzaA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v26 | MYOSIN VI (Sus scrofa) |
PF00063(Myosin_head) | 4 | VAL A 164SER A 664ILE A 488PHE A 484 | None | 0.87A | 5jw1A-2v26A:undetectable | 5jw1A-2v26A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhf | UBIQUITINCARBOXYL-TERMINALHYDROLASE CYLD (Homo sapiens) |
PF00443(UCH) | 4 | VAL A 696LEU A 752ILE A 777PHE A 745 | None | 0.83A | 5jw1A-2vhfA:undetectable | 5jw1A-2vhfA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wmh | FUCOLECTIN-RELATEDPROTEIN (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 4 | VAL A 574LEU A 468SER A 467ILE A 441 | None | 0.94A | 5jw1A-2wmhA:undetectable | 5jw1A-2wmhA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yq1 | ORF73 (Muridgammaherpesvirus4) |
no annotation | 4 | VAL A 234LEU A 195SER A 196PHE A 168 | None | 0.98A | 5jw1A-2yq1A:undetectable | 5jw1A-2yq1A:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z0l | EARLY ANTIGENPROTEIN D (Humangammaherpesvirus4) |
PF04929(Herpes_DNAp_acc) | 4 | VAL A 226LEU A 265ILE A 273PHE A 267 | None | 0.95A | 5jw1A-2z0lA:undetectable | 5jw1A-2z0lA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zuk | ALPHA-AMINO-EPSILON-CAPROLACTAM RACEMASE (Achromobacterobae) |
PF00202(Aminotran_3) | 4 | VAL A 388LEU A 45SER A 46ILE A 403 | None | 0.97A | 5jw1A-2zukA:undetectable | 5jw1A-2zukA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzg | ALANYL-TRNASYNTHETASE (Pyrococcushorikoshii) |
PF01411(tRNA-synt_2c)PF07973(tRNA_SAD) | 4 | VAL A 675LEU A 619ARG A 625ILE A 661 | None | 0.80A | 5jw1A-2zzgA:undetectable | 5jw1A-2zzgA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | VAL A 420LEU A 261SER A 260ILE A 265 | NoneNoneNAD A 550 ( 4.9A)None | 1.06A | 5jw1A-3ce6A:undetectable | 5jw1A-3ce6A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf0 | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Mus musculus) |
PF00004(AAA)PF09336(Vps4_C) | 4 | VAL A 493LEU A 574ILE A 542PHE A 576 | None | 0.68A | 5jw1A-3cf0A:undetectable | 5jw1A-3cf0A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cg1 | UPF0100 PROTEINPF0080 (Pyrococcusfuriosus) |
PF13531(SBP_bac_11) | 4 | LEU A 167SER A 166ILE A 186PHE A 182 | None | 0.98A | 5jw1A-3cg1A:undetectable | 5jw1A-3cg1A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwv | DNA GYRASE, BSUBUNIT, TRUNCATED (Myxococcusxanthus) |
PF00204(DNA_gyraseB) | 4 | LEU A 107SER A 108ILE A 162PHE A 163 | None | 0.96A | 5jw1A-3cwvA:undetectable | 5jw1A-3cwvA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm0 | MALTOSE-BINDINGPERIPLASMIC PROTEINFUSED WITH RACK1 (Arabidopsisthaliana;Escherichiacoli) |
PF00400(WD40)PF01547(SBP_bac_1) | 4 | SER A1122ARG A1157ILE A1167PHE A1158 | None | 1.04A | 5jw1A-3dm0A:undetectable | 5jw1A-3dm0A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3p | PROTEIN KINASE,PUTATIVE GLYCOGENSYNTHASE KINASE (Leishmaniamajor) |
PF00069(Pkinase) | 4 | LEU A 243ARG A 241ILE A 239PHE A 227 | None | 0.89A | 5jw1A-3e3pA:undetectable | 5jw1A-3e3pA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnr | ARGINYL-TRNASYNTHETASE (Campylobacterjejuni) |
PF00750(tRNA-synt_1d)PF05746(DALR_1) | 4 | LEU A 351SER A 350ARG A 125ILE A 121 | None | 0.91A | 5jw1A-3fnrA:undetectable | 5jw1A-3fnrA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ha9 | UNCHARACTERIZEDTHIOREDOXIN-LIKEPROTEIN (Aeropyrumpernix) |
PF00578(AhpC-TSA) | 4 | VAL A 183LEU A 67ILE A 99PHE A 69 | None | 0.93A | 5jw1A-3ha9A:undetectable | 5jw1A-3ha9A:14.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3izq | ELONGATION FACTOR 1ALPHA-LIKE PROTEIN (Saccharomycescerevisiae) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF08938(HBS1_N) | 4 | LEU 1 436SER 1 435ILE 1 430PHE 1 401 | None | 1.01A | 5jw1A-3izq1:undetectable | 5jw1A-3izq1:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4w | UNCHARACTERIZEDPROTEIN BB4693 (Bordetellabronchiseptica) |
PF04909(Amidohydro_2) | 4 | VAL A 133SER A 186ARG A 7PHE A 6 | None | 1.07A | 5jw1A-3k4wA:undetectable | 5jw1A-3k4wA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khs | PURINE NUCLEOSIDEPHOSPHORYLASE (Singaporegrouperiridovirus) |
PF01048(PNP_UDP_1) | 4 | LEU A 65SER A 64ILE A 50PHE A 53 | None | 0.70A | 5jw1A-3khsA:undetectable | 5jw1A-3khsA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpz | GET4 (YOR164CHOMOLOG) (Chaetomiumthermophilum) |
PF04190(DUF410) | 4 | VAL A 106LEU A 74ARG A 79PHE A 78 | None | 0.88A | 5jw1A-3lpzA:undetectable | 5jw1A-3lpzA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgx | PUTATIVE P450MONOOXYGENASE (Amycolatopsisbalhimycina) |
PF00067(p450) | 4 | VAL A 89LEU A 233ILE A 191PHE A 195 | None | 1.03A | 5jw1A-3mgxA:undetectable | 5jw1A-3mgxA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnk | PUTATIVE LIPOPROTEIN (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | VAL A 507LEU A 304ILE A 469PHE A 308 | None | 0.88A | 5jw1A-3qnkA:undetectable | 5jw1A-3qnkA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rui | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME ATG7 (Saccharomycescerevisiae) |
PF00899(ThiF) | 4 | VAL A 437LEU A 448SER A 447ILE A 452 | None | 0.99A | 5jw1A-3ruiA:undetectable | 5jw1A-3ruiA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3stt | METHYLKETONESYNTHASE I (Solanumhabrochaites) |
PF12697(Abhydrolase_6) | 4 | VAL A 208LEU A 258SER A 259PHE A 254 | None | 0.90A | 5jw1A-3sttA:undetectable | 5jw1A-3sttA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tfw | PUTATIVEO-METHYLTRANSFERASE (Klebsiellapneumoniae) |
PF01596(Methyltransf_3) | 4 | VAL A 111LEU A 53ILE A 165PHE A 139 | None | 0.89A | 5jw1A-3tfwA:undetectable | 5jw1A-3tfwA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vh1 | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME ATG7 (Saccharomycescerevisiae) |
PF00899(ThiF)PF16420(ATG7_N) | 4 | VAL A 437LEU A 448SER A 447ILE A 452 | None | 0.82A | 5jw1A-3vh1A:undetectable | 5jw1A-3vh1A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9v | PHOSPHATE-BINDINGPROTEIN (unidentifiedprokaryoticorganism) |
PF12849(PBP_like_2) | 4 | VAL A 368LEU A 83SER A 304ILE A 302 | None | 0.98A | 5jw1A-3w9vA:undetectable | 5jw1A-3w9vA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxf | UNCHARACTERIZEDPROTEIN (Danio rerio) |
PF00443(UCH) | 4 | VAL A 691LEU A 747ILE A 772PHE A 740 | None | 0.82A | 5jw1A-3wxfA:undetectable | 5jw1A-3wxfA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wyf | GSP1P (Saccharomycescerevisiae) |
PF00071(Ras) | 4 | VAL A 10LEU A 52SER A 53PHE A 163 | None | 0.86A | 5jw1A-3wyfA:undetectable | 5jw1A-3wyfA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdr | ALCOHOLDEHYDROGENASE DOMAINOF THE BIFUNCTIONALACETALDEHYDEDEHYDROGENASE (Parageobacillusthermoglucosidasius) |
PF00465(Fe-ADH) | 4 | LEU A 858SER A 856ARG A 863ILE A 861 | None | 1.03A | 5jw1A-3zdrA:undetectable | 5jw1A-3zdrA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4anj | UNCONVENTIONALMYOSIN-VI, GREENFLUORESCENT PROTEIN (Aequoreavictoria;Sus scrofa) |
PF00063(Myosin_head)PF01353(GFP) | 4 | VAL A 164SER A 664ILE A 488PHE A 484 | None | 0.86A | 5jw1A-4anjA:undetectable | 5jw1A-4anjA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d6v | G PROTEIN BETASUBUNIT GIB2 (Cryptococcusneoformans) |
PF00400(WD40) | 4 | SER A 122ARG A 155ILE A 165PHE A 156 | None | 1.00A | 5jw1A-4d6vA:undetectable | 5jw1A-4d6vA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwm | UNCHARACTERIZEDPROTEIN YEDD (Klebsiellapneumoniae) |
PF13987(YedD) | 4 | VAL A 74LEU A 57SER A 56ILE A 107 | None | 0.88A | 5jw1A-4hwmA:undetectable | 5jw1A-4hwmA:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ir8 | SEDOHEPTULOSE-1,7BISPHOSPHATASE,PUTATIVE (Toxoplasmagondii) |
PF00316(FBPase) | 4 | VAL A 177LEU A 155SER A 154ILE A 30 | None | 1.06A | 5jw1A-4ir8A:undetectable | 5jw1A-4ir8A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kk1 | TUBEROUS SCLEROSIS 1PROTEIN HOMOLOG (Schizosaccharomycespombe) |
PF04388(Hamartin) | 4 | VAL A 234LEU A 190SER A 191ILE A 144 | None | 0.96A | 5jw1A-4kk1A:undetectable | 5jw1A-4kk1A:20.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ph9 | PROSTAGLANDIN G/HSYNTHASE 2 (Mus musculus) |
PF00008(EGF)PF03098(An_peroxidase) | 6 | VAL A 117LEU A 353SER A 354ARG A 514ILE A 518PHE A 519 | BOG A 604 (-3.9A)IBP A 601 ( 4.7A)NoneNoneNoneNone | 0.47A | 5jw1A-4ph9A:62.6 | 5jw1A-4ph9A:99.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phc | HISTIDINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF03129(HGTP_anticodon)PF13393(tRNA-synt_His) | 4 | VAL A 249LEU A 322SER A 323ILE A 216 | None | 1.04A | 5jw1A-4phcA:undetectable | 5jw1A-4phcA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psm | SSDNA BINDINGPROTEIN (Pyrococcusfuriosus) |
PF10015(DUF2258) | 4 | VAL A 9LEU A 22ILE A 74PHE A 67 | None | 1.07A | 5jw1A-4psmA:undetectable | 5jw1A-4psmA:14.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdk | MAGNESIUM-PROTOPORPHYRINO-METHYLTRANSFERASE (Synechocystissp. PCC 6803) |
PF07109(Mg-por_mtran_C) | 4 | LEU A 162SER A 163ARG A 223ILE A 198 | None | 1.01A | 5jw1A-4qdkA:undetectable | 5jw1A-4qdkA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qg5 | PUTATIVEPHOSPHOGLUCOMUTASE (Leishmaniamajor) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | VAL A 250LEU A 115ILE A 130PHE A 128 | None | 0.97A | 5jw1A-4qg5A:undetectable | 5jw1A-4qg5A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qlx | NITROREDUCTASEFAMILY PROTEIN (Lactobacillusplantarum) |
PF00881(Nitroreductase) | 4 | VAL A 100SER A 55ILE A 91PHE A 58 | None | 1.05A | 5jw1A-4qlxA:undetectable | 5jw1A-4qlxA:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qvr | UNCHARACTERIZEDHYPOTHETICAL PROTEINFTT_1539C (Francisellatularensis) |
no annotation | 4 | LEU A 217SER A 216ILE A 130PHE A 221 | None | 0.99A | 5jw1A-4qvrA:undetectable | 5jw1A-4qvrA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | LEU A2644SER A2645ARG A2642ILE A2640 | None | 1.05A | 5jw1A-4rh7A:undetectable | 5jw1A-4rh7A:9.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4sli | INTRAMOLECULARTRANS-SIALIDASE (Macrobdelladecora) |
PF02973(Sialidase)PF13088(BNR_2) | 4 | VAL A 724LEU A 647SER A 665ILE A 617 | None | 1.03A | 5jw1A-4sliA:undetectable | 5jw1A-4sliA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uf3 | ANTIAPOPTOTICMEMBRANE PROTEIN (Mule deerpoxvirus) |
PF11099(M11L) | 4 | LEU A 92SER A 89ILE A 136PHE A 132 | None | 1.02A | 5jw1A-4uf3A:undetectable | 5jw1A-4uf3A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzf | BAND 3 ANIONTRANSPORT PROTEIN (Homo sapiens) |
PF00955(HCO3_cotransp) | 4 | VAL A 513LEU A 382ARG A 388ILE A 386 | None | 1.03A | 5jw1A-4yzfA:undetectable | 5jw1A-4yzfA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zem | TRANSLATIONINITIATION FACTOREIF2B-LIKEPROTEIN,TRANSLATIONINITIATION FACTOREIF2B-LIKE PROTEIN (Chaetomiumthermophilum) |
PF01008(IF-2B) | 4 | VAL A 274LEU A 222ARG A 290ILE A 288 | None | 1.00A | 5jw1A-4zemA:2.5 | 5jw1A-4zemA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a08 | PROBABLEMANNOSYLTRANSFERASEKTR4 (Saccharomycescerevisiae) |
PF01793(Glyco_transf_15) | 4 | VAL A 119LEU A 461ILE A 452PHE A 109 | None | 1.07A | 5jw1A-5a08A:undetectable | 5jw1A-5a08A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cr9 | ABC-TYPEFE3+-HYDROXAMATETRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Saccharomonosporaviridis) |
PF01497(Peripla_BP_2) | 4 | VAL A 278LEU A 64ARG A 84ILE A 62 | None | 0.91A | 5jw1A-5cr9A:undetectable | 5jw1A-5cr9A:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d91 | AF2299PROTEIN,PHOSPHATIDYLINOSITOL SYNTHASE (Archaeoglobusfulgidus;Renibacteriumsalmoninarum) |
PF01066(CDP-OH_P_transf) | 4 | VAL A 157LEU A 125SER A 126ILE A 188 | None | 1.01A | 5jw1A-5d91A:0.6 | 5jw1A-5d91A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dld | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Burkholderiavietnamiensis) |
PF02350(Epimerase_2) | 4 | VAL A 93LEU A 134ARG A 122ILE A 126 | None | 1.03A | 5jw1A-5dldA:undetectable | 5jw1A-5dldA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f3y | UNCONVENTIONALMYOSIN-VIIB (Mus musculus) |
PF00784(MyTH4) | 4 | VAL A1072LEU A1117SER A1114ILE A1134 | None | 1.00A | 5jw1A-5f3yA:1.4 | 5jw1A-5f3yA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fno | MANGANESELIPOXYGENASE (Magnaportheoryzae) |
PF00305(Lipoxygenase) | 4 | VAL A 372LEU A 398SER A 396ARG A 403 | None | 0.93A | 5jw1A-5fnoA:0.9 | 5jw1A-5fnoA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 4 | LEU A 804SER A 805ILE A 793PHE A 800 | None | 1.02A | 5jw1A-5h42A:undetectable | 5jw1A-5h42A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hyp | C4B-BINDING PROTEINALPHA CHAIN (Homo sapiens) |
PF00084(Sushi) | 4 | VAL A 38LEU A 82SER A 83ILE A 88 | None | 0.84A | 5jw1A-5hypA:undetectable | 5jw1A-5hypA:11.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijb | TOLL-LIKE RECEPTOR4, VARIABLELYMPHOCYTE RECEPTORB CHIMERA (Eptatretusburgeri;Mus musculus) |
PF00560(LRR_1)PF11921(DUF3439)PF13855(LRR_8) | 4 | LEU A 232SER A 210ILE A 214PHE A 236 | None | 0.98A | 5jw1A-5ijbA:undetectable | 5jw1A-5ijbA:22.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikr | PROSTAGLANDIN G/HSYNTHASE 2 (Homo sapiens) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | LEU A 352SER A 353ARG A 513ILE A 517PHE A 518 | ID8 A 601 (-4.1A)ID8 A 601 ( 4.7A)NoneNoneNone | 0.58A | 5jw1A-5ikrA:61.3 | 5jw1A-5ikrA:87.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikr | PROSTAGLANDIN G/HSYNTHASE 2 (Homo sapiens) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | VAL A 116SER A 353ARG A 513ILE A 517PHE A 518 | NoneID8 A 601 ( 4.7A)NoneNoneNone | 0.28A | 5jw1A-5ikrA:61.3 | 5jw1A-5ikrA:87.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iy3 | GENOME POLYPROTEIN (Zika virus) |
PF00948(Flavi_NS1) | 4 | LEU A 321ARG A 324ILE A 275PHE A 323 | None | 1.07A | 5jw1A-5iy3A:undetectable | 5jw1A-5iy3A:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l44 | K-26 DIPEPTIDYLCARBOXYPEPTIDASE (Astrosporangiumhypotensionis) |
PF01432(Peptidase_M3) | 4 | VAL A 49LEU A 105ILE A 101PHE A 38 | None | 1.06A | 5jw1A-5l44A:2.3 | 5jw1A-5l44A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o82 | INTRACELLULAREXO-ALPHA-(1->5)-L-ARABINOFURANOSIDASE (Chaetomiumthermophilum) |
no annotation | 4 | VAL A 228LEU A 241SER A 240ILE A 345 | None | 1.02A | 5jw1A-5o82A:undetectable | 5jw1A-5o82A:10.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojs | TRANSCRIPTION-ASSOCIATED PROTEIN 1 (Saccharomycescerevisiae) |
PF00454(PI3_PI4_kinase)PF02259(FAT) | 4 | VAL T3047LEU T3086SER T3083ILE T3104 | None | 0.94A | 5jw1A-5ojsT:undetectable | 5jw1A-5ojsT:9.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vem | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 5 (Homo sapiens) |
PF01663(Phosphodiest) | 4 | LEU A 43ARG A 39ILE A 351PHE A 38 | None | 0.93A | 5jw1A-5vemA:undetectable | 5jw1A-5vemA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5veo | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 5 (Mus musculus) |
PF01663(Phosphodiest) | 4 | LEU A 43ARG A 39ILE A 351PHE A 38 | None | 0.96A | 5jw1A-5veoA:undetectable | 5jw1A-5veoA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyw | PYRUVATE CARBOXYLASE (Lactococcuslactis) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | VAL A 515LEU A 563SER A 565ILE A 556 | None | 1.06A | 5jw1A-5vywA:undetectable | 5jw1A-5vywA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w6m | HISTIDINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
no annotation | 4 | VAL A 249LEU A 322SER A 323ILE A 216 | None | 0.84A | 5jw1A-5w6mA:undetectable | 5jw1A-5w6mA:11.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7q | CONSENSUS ELONGATIONFACTOR (syntheticconstruct) |
no annotation | 4 | LEU A 158SER A 159ARG A 124ILE A 120 | None | 0.90A | 5jw1A-5w7qA:undetectable | 5jw1A-5w7qA:8.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6x | MRNA CAPPING ENZYMEP5 (Rice dwarfvirus) |
no annotation | 4 | VAL C 206LEU C 277SER C 278ILE C 283 | None | 1.05A | 5jw1A-5x6xC:undetectable | 5jw1A-5x6xC:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yc1 | TNFRECEPTOR-ASSOCIATEDFACTOR 4 (Homo sapiens) |
no annotation | 4 | VAL A 309LEU A 390SER A 389ILE A 440 | None | 0.86A | 5jw1A-5yc1A:undetectable | 5jw1A-5yc1A:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yud | BACULOVIRAL IAPREPEAT-CONTAININGPROTEIN 1E (Mus musculus) |
no annotation | 4 | VAL A 468LEU A 504SER A 505ILE A 509 | None | 1.06A | 5jw1A-5yudA:undetectable | 5jw1A-5yudA:9.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zct | - (-) |
no annotation | 4 | VAL A 198LEU A 242ARG A 64ILE A 94 | None | 0.97A | 5jw1A-5zctA:undetectable | 5jw1A-5zctA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aun | PLA2G6, IPLA2BETA (Cricetulusgriseus) |
no annotation | 4 | VAL A 461LEU A 442ILE A 735PHE A 742 | None | 0.97A | 5jw1A-6aunA:undetectable | 5jw1A-6aunA:11.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eys | - (-) |
no annotation | 4 | LEU B 66ARG B 182ILE B 167PHE B 181 | None | 1.02A | 5jw1A-6eysB:undetectable | 5jw1A-6eysB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g8r | NUCLEAR BODY PROTEINSP140 (Homo sapiens) |
no annotation | 4 | VAL B 857ARG B 824ILE B 826PHE B 827 | None | 0.96A | 5jw1A-6g8rB:undetectable | 5jw1A-6g8rB:8.69 |