SIMILAR PATTERNS OF AMINO ACIDS FOR 5JQ7_B_T0RB705

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b72 PROTEIN (HOMEOBOX
PROTEIN HOX-B1)

(Homo sapiens) 		PF00046
(Homeobox) 		5 VAL A 247
LEU A 218
GLU A 244
ALA A 237
LEU A 228
 None
 1.20A 5jq7A-1b72A:
undetectable		 5jq7A-1b72A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4t PROTEIN
(DIHYDROLIPOAMIDE
SUCCINYLTRANSFERASE)

(Escherichia
coli) 		PF00198
(2-oxoacid_dh) 		5 VAL A 241
LEU A 245
ALA A 240
LEU A 345
LEU A 369
 None
 1.33A 5jq7A-1c4tA:
0.0		 5jq7A-1c4tA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL O 305
LEU O 307
ALA O 299
LEU O 246
 None
 0.59A 5jq7A-1gaeO:
0.0		 5jq7A-1gaeO:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gr0 INOSITOL-3-PHOSPHATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF01658
(Inos-1-P_synth) 		4 VAL A  21
LEU A 146
LEU A 142
LEU A 134
 NAD  A1000 ( 4.8A)
None
None
None
 0.65A 5jq7A-1gr0A:
0.0		 5jq7A-1gr0A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idm 3-ISOPROPYLMALATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 VAL A   3
GLU A  65
ALA A  66
LEU A  34
 None
 0.44A 5jq7A-1idmA:
0.0		 5jq7A-1idmA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 VAL A1118
LEU A1123
ALA A1098
LEU A1113
 None
 0.60A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 VAL A1264
LEU A1269
ALA A1244
LEU A1259
 None
 0.66A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 VAL A1324
LEU A1329
ALA A1304
LEU A1319
 None
 0.57A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 VAL A1364
LEU A1369
ALA A1344
LEU A1359
 None
 0.59A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN

(Homo sapiens) 		PF01852
(START) 		4 VAL A 132
LEU A 134
ALA A 160
LEU A 123
 None
 0.62A 5jq7A-1ln1A:
0.0		 5jq7A-1ln1A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpe APOLIPOPROTEIN E3

(Homo sapiens) 		PF01442
(Apolipoprotein) 		5 ARG A 114
VAL A 111
LEU A  60
LEU A 141
LEU A 137
 None
 1.24A 5jq7A-1lpeA:
undetectable		 5jq7A-1lpeA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1puf HOMEOBOX PROTEIN
HOX-A9

(Mus musculus) 		PF00046
(Homeobox) 		5 VAL A 249
LEU A 220
GLU A 246
ALA A 239
LEU A 230
 None
 1.25A 5jq7A-1pufA:
undetectable		 5jq7A-1pufA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pyb METHIONYL-TRNA
SYNTHETASE BETA
SUBUNIT

(Aquifex
aeolicus) 		PF01588
(tRNA_bind) 		4 ARG A  46
VAL A  48
LEU A  39
LEU A  41
 None
 0.61A 5jq7A-1pybA:
undetectable		 5jq7A-1pybA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9a UROPORPHYRIN-III
C-METHYLTRANSFERASE

(Thermus
thermophilus) 		PF00590
(TP_methylase) 		4 VAL A 157
LEU A 123
ALA A 134
LEU A 216
 None
None
None
SAH  A 501 (-4.4A)
 0.64A 5jq7A-1v9aA:
undetectable		 5jq7A-1v9aA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xn4 RIBONUCLEASE MAR1

(Leishmania
major) 		PF00857
(Isochorismatase) 		4 VAL A 127
LEU A 129
ALA A 102
LEU A 121
 None
 0.68A 5jq7A-1xn4A:
0.0		 5jq7A-1xn4A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aka DYNAMIN-1

(Rattus
norvegicus) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 VAL B 124
ALA B  81
LEU B  71
LEU B  69
 None
 0.51A 5jq7A-2akaB:
undetectable		 5jq7A-2akaB:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 VAL C  56
ALA C 124
LEU C  37
LEU C  35
 None
 0.67A 5jq7A-2bg9C:
undetectable		 5jq7A-2bg9C:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bnh RIBONUCLEASE
INHIBITOR

(Sus scrofa) 		PF13516
(LRR_6) 		4 VAL A 315
LEU A 320
LEU A 341
LEU A 338
 None
 0.66A 5jq7A-2bnhA:
undetectable		 5jq7A-2bnhA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dno TRINUCLEOTIDE REPEAT
CONTAINING 4 VARIANT

(Homo sapiens) 		PF00076
(RRM_1) 		4 VAL A  75
ALA A 114
LEU A 144
LEU A 137
 None
 0.67A 5jq7A-2dnoA:
undetectable		 5jq7A-2dnoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwc 433AA LONG
HYPOTHETICAL
PHOSPHORIBOSYLGLYCIN
AMIDE FORMYL
TRANSFERASE

(Pyrococcus
horikoshii) 		PF02222
(ATP-grasp) 		4 VAL A 373
LEU A 375
ALA A 390
LEU A 366
 None
 0.57A 5jq7A-2dwcA:
undetectable		 5jq7A-2dwcA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6k TRANSKETOLASE

(Thermus
thermophilus) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		5 ARG A 642
VAL A 643
LEU A 546
GLU A 645
ALA A 646
 None
 1.23A 5jq7A-2e6kA:
undetectable		 5jq7A-2e6kA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fym ENOLASE

(Escherichia
coli) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		5 VAL A 224
LEU A 215
GLU A 227
ALA A 223
LEU A 192
 None
 1.46A 5jq7A-2fymA:
undetectable		 5jq7A-2fymA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l9r HOMEOBOX PROTEIN
NKX-3.1

(Homo sapiens) 		PF00046
(Homeobox) 		5 VAL A  48
LEU A  19
GLU A  45
ALA A  38
LEU A  29
 None
 1.29A 5jq7A-2l9rA:
undetectable		 5jq7A-2l9rA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mk4 OPEN READING FRAME 2

(Aeromonas
sobria) 		no annotation 5 VAL A  68
LEU A  96
GLU A  69
ALA A  70
LEU A 111
 None
 1.00A 5jq7A-2mk4A:
undetectable		 5jq7A-2mk4A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq3 ITCHY HOMOLOG E3
UBIQUITIN PROTEIN
LIGASE

(Homo sapiens) 		PF00168
(C2) 		4 VAL A 118
LEU A 120
LEU A 139
LEU A 113
 None
 0.57A 5jq7A-2nq3A:
undetectable		 5jq7A-2nq3A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okc TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 VAL A 304
LEU A 306
ALA A 258
LEU A 296
 None
 0.66A 5jq7A-2okcA:
undetectable		 5jq7A-2okcA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Cupriavidus
pinatubonensis) 		PF02627
(CMD) 		5 VAL A 110
LEU A  97
ALA A 111
LEU A 127
LEU A 131
 None
 1.09A 5jq7A-2prrA:
undetectable		 5jq7A-2prrA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3s UNCHARACTERIZED
PROTEIN

(Nostoc
punctiforme) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 VAL A 266
ALA A 332
LEU A 237
LEU A 241
 None
 0.58A 5jq7A-2r3sA:
undetectable		 5jq7A-2r3sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6i UNCHARACTERIZED
PROTEIN ATU1473

(Agrobacterium
fabrum) 		PF07542
(ATP12) 		5 VAL A  97
LEU A  64
ALA A 100
LEU A  71
LEU A 260
 None
 1.09A 5jq7A-2r6iA:
undetectable		 5jq7A-2r6iA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1u CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG

(Aeropyrum
pernix) 		PF09079
(Cdc6_C)
PF13191
(AAA_16) 		4 ARG A 225
LEU A 235
GLU A 228
ALA A 229
 ADP  A1400 (-3.3A)
None
None
None
 0.49A 5jq7A-2v1uA:
undetectable		 5jq7A-2v1uA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE

(Paenarthrobacter
nicotinovorans) 		PF00070
(Pyr_redox) 		4 VAL A 130
ALA A 142
LEU A 123
LEU A 120
 None
None
None
FAD  A1395 (-4.6A)
 0.62A 5jq7A-2vouA:
undetectable		 5jq7A-2vouA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 VAL A 586
LEU A 626
ALA A 576
LEU A 634
 None
 0.68A 5jq7A-2wpgA:
undetectable		 5jq7A-2wpgA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsm HYDROGENASE
EXPRESSION/FORMATION
PROTEIN (HYPB)

(Archaeoglobus
fulgidus) 		PF02492
(cobW) 		4 ARG A  49
LEU A 113
GLU A  52
LEU A 195
 None
 0.66A 5jq7A-2wsmA:
undetectable		 5jq7A-2wsmA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xly CLOQ

(Streptomyces
roseochromogenus) 		PF11468
(PTase_Orf2) 		4 VAL A 173
ALA A 162
LEU A 220
LEU A 222
 None
 0.59A 5jq7A-2xlyA:
undetectable		 5jq7A-2xlyA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yq4 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE

(Lactobacillus
delbrueckii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A  49
LEU A  51
ALA A   5
LEU A  66
 None
 0.57A 5jq7A-2yq4A:
undetectable		 5jq7A-2yq4A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 VAL A 464
LEU A 469
LEU A 482
LEU A 479
 None
 0.66A 5jq7A-2z7xA:
undetectable		 5jq7A-2z7xA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z81 TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13306
(LRR_5)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 VAL A 464
LEU A 469
LEU A 482
LEU A 479
 None
 0.62A 5jq7A-2z81A:
undetectable		 5jq7A-2z81A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zfu CEREBRAL PROTEIN 1

(Homo sapiens) 		PF05148
(Methyltransf_8) 		4 VAL A 390
LEU A 388
LEU A 366
LEU A 448
 None
 0.69A 5jq7A-2zfuA:
undetectable		 5jq7A-2zfuA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aup BASIC 7S GLOBULIN

(Glycine max) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 VAL A 316
LEU A 318
LEU A 335
LEU A 346
 None
 0.44A 5jq7A-3aupA:
undetectable		 5jq7A-3aupA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aw5 MULTICOPPER OXIDASE

(Pyrobaculum
aerophilum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 276
LEU A 278
LEU A 220
LEU A 222
 None
 0.59A 5jq7A-3aw5A:
undetectable		 5jq7A-3aw5A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bre PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR

(Pseudomonas
aeruginosa) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		5 VAL A  34
LEU A 129
GLU A  32
ALA A  33
LEU A  23
 None
 1.22A 5jq7A-3breA:
undetectable		 5jq7A-3breA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cps GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Cryptosporidium
parvum) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL A 326
LEU A 328
ALA A 320
LEU A 267
 None
 0.47A 5jq7A-3cpsA:
undetectable		 5jq7A-3cpsA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvr INVASION PLASMID
ANTIGEN

(Shigella
flexneri) 		PF12468
(TTSSLRR)
PF14496
(NEL) 		4 VAL A 127
LEU A 132
ALA A 107
LEU A 122
 None
 0.65A 5jq7A-3cvrA:
undetectable		 5jq7A-3cvrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6c THERMONUCLEASE

(Staphylococcus
aureus) 		PF00565
(SNase) 		4 VAL A  23
LEU A  25
ALA A  17
LEU A  36
 None
 0.68A 5jq7A-3d6cA:
undetectable		 5jq7A-3d6cA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6c THERMONUCLEASE

(Staphylococcus
aureus) 		PF00565
(SNase) 		4 VAL A  23
LEU A  25
ALA A  17
LEU A 103
 None
 0.65A 5jq7A-3d6cA:
undetectable		 5jq7A-3d6cA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		4 VAL A 349
LEU A 354
ALA A 329
LEU A 344
 None
 0.56A 5jq7A-3g06A:
undetectable		 5jq7A-3g06A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		4 VAL A 389
LEU A 394
ALA A 369
LEU A 384
 None
 0.59A 5jq7A-3g06A:
undetectable		 5jq7A-3g06A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus) 		PF02527
(GidB) 		4 VAL A 224
ALA A 182
LEU A 206
LEU A 199
 None
 0.42A 5jq7A-3g8aA:
undetectable		 5jq7A-3g8aA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM

(Serratia
plymuthica) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 VAL A 521
LEU A 561
ALA A 508
LEU A 571
 None
 0.65A 5jq7A-3gbdA:
undetectable		 5jq7A-3gbdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go4 PROTEIN OF UNKNOWN
FUNCTION DUF574

(Streptomyces
avermitilis) 		PF04672
(Methyltransf_19) 		4 ARG A 152
ALA A 148
LEU A 155
LEU A 157
 None
 0.67A 5jq7A-3go4A:
undetectable		 5jq7A-3go4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 ARG X1004
VAL X1006
LEU X1008
LEU X 765
 None
 0.55A 5jq7A-3jb9X:
undetectable		 5jq7A-3jb9X:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsj PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
avermitilis) 		PF00440
(TetR_N) 		5 ARG A 104
VAL A 108
LEU A 112
ALA A 107
LEU A  59
 EDO  A 191 (-2.6A)
None
None
None
None
 1.27A 5jq7A-3jsjA:
undetectable		 5jq7A-3jsjA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l12 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Ruegeria
pomeroyi) 		PF03009
(GDPD) 		5 VAL A 169
LEU A 128
ALA A 168
LEU A 149
LEU A 191
 None
 1.31A 5jq7A-3l12A:
undetectable		 5jq7A-3l12A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l43 DYNAMIN-3

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 VAL A 124
ALA A  81
LEU A  71
LEU A  69
 None
 0.56A 5jq7A-3l43A:
undetectable		 5jq7A-3l43A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7o LYMPHOCYTE ANTIGEN
86

(Mus musculus) 		PF02221
(E1_DerP2_DerF2) 		4 VAL A  40
LEU A  38
ALA A  32
LEU A 142
 None
None
None
L9R  A 301 (-4.0A)
 0.66A 5jq7A-3m7oA:
undetectable		 5jq7A-3m7oA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nct PROTEIN PSIB

(Escherichia
coli) 		PF06290
(PsiB) 		5 VAL A 113
LEU A  89
GLU A 111
ALA A 112
LEU A  40
 None
 1.41A 5jq7A-3nctA:
undetectable		 5jq7A-3nctA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		5 VAL A 103
LEU A 133
GLU A 101
ALA A 102
LEU A  89
 None
 1.37A 5jq7A-3oepA:
undetectable		 5jq7A-3oepA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrv ENOYL-COA
HYDRATASE/ISOMERASE

(Mycobacterium
avium) 		PF00378
(ECH_1) 		5 VAL A  93
LEU A 121
GLU A  91
LEU A 227
LEU A 231
 None
 1.33A 5jq7A-3rrvA:
undetectable		 5jq7A-3rrvA:
19.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3s88 ENVELOPE
GLYCOPROTEIN

(Sudan
ebolavirus) 		PF01611
(Filo_glycop) 		6 VAL I  66
LEU I  68
GLU I 100
ALA I 101
LEU I 184
LEU I 186
 None
 0.53A 5jq7A-3s88I:
28.5		 5jq7A-3s88I:
63.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tzw POLYKETIDE SYNTHASE
PKS13

(Mycobacterium
tuberculosis) 		PF00698
(Acyl_transf_1) 		4 ARG A 674
VAL A 676
LEU A 678
ALA A 628
 None
 0.60A 5jq7A-3tzwA:
undetectable		 5jq7A-3tzwA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v7i PUTATIVE POLYKETIDE
SYNTHASE

(Streptomyces
coelicolor) 		PF00195
(Chal_sti_synt_N) 		4 VAL A 200
ALA A 231
LEU A 155
LEU A 159
 None
 0.67A 5jq7A-3v7iA:
undetectable		 5jq7A-3v7iA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16

(Homo sapiens) 		PF01419
(Jacalin) 		5 VAL A  97
LEU A 139
ALA A 130
LEU A 108
LEU A 105
 None
 0.88A 5jq7A-3vzgA:
undetectable		 5jq7A-3vzgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnp CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Bacillus
circulans) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 VAL A 307
ALA A 234
LEU A 351
LEU A 341
 None
 0.61A 5jq7A-3wnpA:
undetectable		 5jq7A-3wnpA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a4z ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		4 VAL A1252
LEU A1264
GLU A1251
LEU A1150
 None
 0.63A 5jq7A-4a4zA:
undetectable		 5jq7A-4a4zA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0n POLYKETIDE SYNTHASE
III

(Ectocarpus
siliculosus) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 VAL A 221
LEU A 223
LEU A 170
LEU A 174
 None
 0.67A 5jq7A-4b0nA:
undetectable		 5jq7A-4b0nA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b43 TRANSLATION
INITIATION FACTOR
IF-2

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF04760
(IF2_N) 		5 VAL A  46
LEU A  23
GLU A  44
ALA A  45
LEU A   9
 None
 1.33A 5jq7A-4b43A:
undetectable		 5jq7A-4b43A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgb PUTATIVE SUGAR
KINASE MK0840

(Methanopyrus
kandleri) 		PF03702
(AnmK) 		4 VAL A 166
ALA A 170
LEU A 295
LEU A 293
 None
 0.59A 5jq7A-4bgbA:
undetectable		 5jq7A-4bgbA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4boo ACETYLCHOLINE
RECEPTOR DELTA
SUBUNIT

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 VAL C  56
ALA C 124
LEU C  37
LEU C  35
 None
 0.67A 5jq7A-4booC:
undetectable		 5jq7A-4booC:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buj ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT) 		4 VAL A1252
LEU A1264
GLU A1251
LEU A1150
 None
 0.57A 5jq7A-4bujA:
undetectable		 5jq7A-4bujA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cxk ARYLSULFATASE

(Pseudomonas
aeruginosa) 		PF00884
(Sulfatase) 		4 VAL A 476
LEU A 478
ALA A 467
LEU A 492
 None
 0.65A 5jq7A-4cxkA:
undetectable		 5jq7A-4cxkA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4got METHIONINE-BINDING
LIPOPROTEIN METQ

(Bacillus
subtilis) 		PF03180
(Lipoprotein_9) 		4 VAL A  35
ALA A  82
LEU A  60
LEU A  53
 None
 0.67A 5jq7A-4gotA:
undetectable		 5jq7A-4gotA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 VAL A 548
LEU A 588
ALA A 535
LEU A 598
 None
 0.68A 5jq7A-4hozA:
undetectable		 5jq7A-4hozA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n68 CONTACTIN-5

(Homo sapiens) 		PF00041
(fn3) 		4 VAL A 894
ALA A 884
LEU A 937
LEU A 940
 None
 0.65A 5jq7A-4n68A:
undetectable		 5jq7A-4n68A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkh E3 UBIQUITIN-PROTEIN
LIGASE SSPH1

(Salmonella
enterica) 		no annotation 4 VAL A 284
LEU A 289
ALA A 264
LEU A 279
 None
 0.55A 5jq7A-4nkhA:
undetectable		 5jq7A-4nkhA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkh E3 UBIQUITIN-PROTEIN
LIGASE SSPH1

(Salmonella
enterica) 		no annotation 4 VAL A 344
LEU A 349
ALA A 324
LEU A 339
 None
 0.59A 5jq7A-4nkhA:
undetectable		 5jq7A-4nkhA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o59 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Bos taurus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL O 305
LEU O 307
ALA O 299
LEU O 246
 None
 0.58A 5jq7A-4o59O:
undetectable		 5jq7A-4o59O:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		4 VAL A 118
LEU A 123
ALA A  98
LEU A 113
 None
 0.55A 5jq7A-4ow2A:
undetectable		 5jq7A-4ow2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		4 VAL A 180
LEU A 185
ALA A 160
LEU A 175
 None
 0.58A 5jq7A-4ow2A:
undetectable		 5jq7A-4ow2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		4 VAL A 300
LEU A 305
ALA A 280
LEU A 295
 None
 0.67A 5jq7A-4ow2A:
undetectable		 5jq7A-4ow2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		4 VAL A 360
LEU A 365
ALA A 340
LEU A 355
 None
 0.66A 5jq7A-4ow2A:
undetectable		 5jq7A-4ow2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		4 VAL A 420
LEU A 425
ALA A 400
LEU A 415
 None
 0.56A 5jq7A-4ow2A:
undetectable		 5jq7A-4ow2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		4 VAL A 460
LEU A 465
ALA A 440
LEU A 455
 None
 0.64A 5jq7A-4ow2A:
undetectable		 5jq7A-4ow2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4per RIBONUCLEASE
INHIBITOR

(Gallus gallus) 		PF13516
(LRR_6) 		4 VAL A 315
LEU A 320
LEU A 341
LEU A 338
 None
 0.68A 5jq7A-4perA:
undetectable		 5jq7A-4perA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4prk 4-PHOSPHOERYTHRONATE
DEHYDROGENASE

(Lactobacillus
jensenii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 VAL A  48
LEU A  50
ALA A   4
LEU A  65
 None
 0.57A 5jq7A-4prkA:
undetectable		 5jq7A-4prkA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r85 CYTOSINE DEAMINASE

(Klebsiella
pneumoniae) 		PF07969
(Amidohydro_3) 		5 VAL A 384
LEU A 326
GLU A 382
ALA A 383
LEU A 341
 None
 1.41A 5jq7A-4r85A:
undetectable		 5jq7A-4r85A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ras OXIDOREDUCTASE,
NAD-BINDING/IRON-SUL
FUR CLUSTER-BINDING
PROTEIN

(Nitratireductor
pacificus) 		PF12838
(Fer4_7)
PF13486
(Dehalogenase) 		4 ARG A 351
LEU A 496
GLU A 354
ALA A 355
 None
 0.67A 5jq7A-4rasA:
undetectable		 5jq7A-4rasA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u28 PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
sviceus) 		PF00977
(His_biosynth) 		4 VAL A  16
ALA A  21
LEU A  55
LEU A  53
 None
 0.66A 5jq7A-4u28A:
undetectable		 5jq7A-4u28A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1a MITORIBOSOMAL
PROTEIN ML48, MRPL48

(Sus scrofa) 		no annotation 4 VAL k 186
LEU k 184
GLU k 188
LEU k 162
 None
 0.68A 5jq7A-4v1ak:
undetectable		 5jq7A-4v1ak:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yok PUTATIVE FLAGELLAR
PROTEIN FLIS

(Parabacteroides
merdae) 		PF12866
(DUF3823) 		4 VAL A  73
LEU A  47
LEU A  56
LEU A  90
 None
 0.67A 5jq7A-4yokA:
undetectable		 5jq7A-4yokA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0h GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
GAPC1, CYTOSOLIC

(Arabidopsis
thaliana) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL O 305
LEU O 307
ALA O 299
LEU O 246
 None
 0.51A 5jq7A-4z0hO:
undetectable		 5jq7A-4z0hO:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a3f DYNAMIN 3

(Homo sapiens) 		PF00169
(PH)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		4 VAL A 124
ALA A  81
LEU A  71
LEU A  69
 None
 0.57A 5jq7A-5a3fA:
undetectable		 5jq7A-5a3fA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC

(Mus musculus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL O 412
LEU O 414
ALA O 406
LEU O 353
 None
 0.56A 5jq7A-5c7iO:
undetectable		 5jq7A-5c7iO:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC

(Homo sapiens) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL O 380
LEU O 382
ALA O 374
LEU O 321
 None
 0.59A 5jq7A-5c7oO:
undetectable		 5jq7A-5c7oO:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d3q DYNAMIN-1,DYNAMIN-1

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 VAL A 124
ALA A  81
LEU A  71
LEU A  69
 None
 0.50A 5jq7A-5d3qA:
undetectable		 5jq7A-5d3qA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eio N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE/N-ACET
YL-GAMMA-AMINOADIPYL
-PHOSPHATE REDUCTASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A 173
LEU A 175
ALA A 240
LEU A 217
 None
 0.54A 5jq7A-5eioA:
undetectable		 5jq7A-5eioA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5erb POLYKETIDE SYNTHASE

(Bacillus
amyloliquefaciens) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 VAL A 128
GLU A 203
ALA A 204
LEU A 116
 None
 0.59A 5jq7A-5erbA:
undetectable		 5jq7A-5erbA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		5 VAL A 378
LEU A 402
ALA A 379
LEU A 469
LEU A 581
 None
 1.36A 5jq7A-5ereA:
undetectable		 5jq7A-5ereA:
22.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1b GP1

(Zaire
ebolavirus) 		PF01611
(Filo_glycop) 		6 VAL A  66
LEU A  68
GLU A 100
ALA A 101
LEU A 184
LEU A 186
 None
 0.44A 5jq7A-5f1bA:
19.2		 5jq7A-5f1bA:
99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f56 SINGLE-STRANDED-DNA-
SPECIFIC EXONUCLEASE

(Deinococcus
radiodurans) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 ARG A  15
GLU A 605
LEU A  18
LEU A  19
 None
 0.67A 5jq7A-5f56A:
undetectable		 5jq7A-5f56A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		4 ARG A 616
VAL A 623
ALA A 577
LEU A 597
 None
 0.59A 5jq7A-5gggA:
undetectable		 5jq7A-5gggA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a88 CHLOROPEROXIDASE L

(Streptomyces
lividans) 		PF00561
(Abhydrolase_1) 		4 LEU A 219
THR A 224
ASP A 226
LEU A 269
 None
 0.92A 5jq7B-1a88A:
undetectable		 5jq7B-1a88A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brt BROMOPEROXIDASE A2

(Kitasatospora
aureofaciens) 		PF00561
(Abhydrolase_1) 		4 LEU A 221
THR A 226
ASP A 228
LEU A 271
 None
 0.93A 5jq7B-1brtA:
undetectable		 5jq7B-1brtA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6b GLUTATHIONE
S-TRANSFERASE

(Arabidopsis
thaliana) 		PF13409
(GST_N_2)
PF14497
(GST_C_3) 		4 LEU A  80
TYR A  79
ASP A  67
LEU A  32
 None
 1.01A 5jq7B-1e6bA:
undetectable		 5jq7B-1e6bA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkh GAMMA LACTAMASE

(Microbacterium) 		PF00561
(Abhydrolase_1) 		4 LEU A 223
THR A 228
ASP A 230
LEU A 273
 None
 0.89A 5jq7B-1hkhA:
undetectable		 5jq7B-1hkhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2q PROTEASOME BETA
SUBUNIT

(Archaeoglobus
fulgidus) 		PF00227
(Proteasome) 		4 LEU H 138
THR H   2
THR H   1
LEU H   6
 None
None
CIB  H1001 (-1.9A)
None
 1.05A 5jq7B-1j2qH:
undetectable		 5jq7B-1j2qH:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C) 		PF00541
(Adeno_knob) 		4 LEU A 457
THR A 403
THR A 404
LEU A 413
 None
 0.89A 5jq7B-1knbA:
undetectable		 5jq7B-1knbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ks9 2-DEHYDROPANTOATE
2-REDUCTASE

(Escherichia
coli) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 LEU A  68
THR A 118
THR A 119
LEU A  19
 None
 1.11A 5jq7B-1ks9A:
undetectable		 5jq7B-1ks9A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhf PROTEIN
(PHOSPHOGLYCERATE
MUTASE)

(Saccharomyces
cerevisiae) 		PF00300
(His_Phos_1) 		4 LEU A  84
TYR A  53
THR A 175
LEU A 158
 None
 1.09A 5jq7B-1qhfA:
0.0		 5jq7B-1qhfA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 LEU A 302
THR A 306
THR A 307
LEU A 291
 None
 0.82A 5jq7B-1qvrA:
0.0		 5jq7B-1qvrA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE ALPHA
SUBUNIT

(Thauera
aromatica) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 LEU A 207
THR A 211
THR A 212
LEU A 227
 None
 0.85A 5jq7B-1sb3A:
0.0		 5jq7B-1sb3A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cnd NADH-DEPENDENT
NITRATE REDUCTASE

(Zea mays) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 LEU A 187
TYR A 152
THR A  65
LEU A 198
 None
None
FAD  A 271 (-4.3A)
None
 1.11A 5jq7B-2cndA:
0.0		 5jq7B-2cndA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwu GLUTAMATE RACEMASE

(Bacillus
anthracis) 		PF01177
(Asp_Glu_race) 		4 TYR A 130
THR A 124
THR A  79
LEU A 184
 None
None
DGL  A 278 (-3.7A)
None
 1.11A 5jq7B-2dwuA:
undetectable		 5jq7B-2dwuA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ehh DIHYDRODIPICOLINATE
SYNTHASE

(Aquifex
aeolicus) 		PF00701
(DHDPS) 		4 LEU A 259
THR A  44
MET A 258
LEU A 290
 None
 1.04A 5jq7B-2ehhA:
0.0		 5jq7B-2ehhA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fcd MYOSIN LIGHT CHAIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A  31
TYR A  30
THR A  60
LEU A  75
 None
 0.92A 5jq7B-2fcdA:
undetectable		 5jq7B-2fcdA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2frv PERIPLASMIC
HYDROGENASE

(Desulfovibrio
gigas) 		no annotation 4 LEU L 490
TYR L 527
THR L 411
LEU L  21
 None
 0.97A 5jq7B-2frvL:
0.0		 5jq7B-2frvL:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jfq GLUTAMATE RACEMASE

(Staphylococcus
aureus) 		PF01177
(Asp_Glu_race) 		4 TYR A 125
THR A 119
THR A  74
LEU A 112
 None
None
DGL  A1267 (-3.7A)
None
 1.03A 5jq7B-2jfqA:
undetectable		 5jq7B-2jfqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhe TRANSCRIPTION
REGULATOR TYRR

(Escherichia
coli) 		PF13188
(PAS_8) 		4 LEU A  54
THR A  14
MET A  55
LEU A  46
 None
AE3  A1191 (-4.3A)
None
None
 1.08A 5jq7B-2jheA:
undetectable		 5jq7B-2jheA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2no5 (S)-2-HALOACID
DEHALOGENASE IVA

(Burkholderia
cepacia) 		PF13419
(HAD_2) 		4 LEU A 105
THR A  15
ASP A 181
LEU A 139
 None
ASL  A  11 ( 3.6A)
ASL  A  11 ( 4.5A)
None
 1.05A 5jq7B-2no5A:
undetectable		 5jq7B-2no5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C

(Escherichia
coli) 		PF05175
(MTS)
PF08468
(MTS_N) 		4 LEU A  11
THR A 106
ASP A  78
LEU A  33
 None
 1.08A 5jq7B-2pjdA:
undetectable		 5jq7B-2pjdA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pma UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		PF05618
(Zn_protease) 		4 LEU A  55
THR A  77
THR A  79
LEU A 118
 None
ACT  A 203 ( 3.8A)
ACT  A 203 (-2.9A)
None
 1.09A 5jq7B-2pmaA:
undetectable		 5jq7B-2pmaA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pw6 UNCHARACTERIZED
PROTEIN YGID

(Escherichia
coli) 		PF02900
(LigB) 		4 LEU A 159
TYR A 240
MET A 155
LEU A 101
 None
 1.00A 5jq7B-2pw6A:
undetectable		 5jq7B-2pw6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8r SENSOR PROTEIN

(Pseudomonas
syringae group
genomosp. 3) 		PF02702
(KdpD) 		4 LEU A 110
THR A 119
THR A 120
LEU A  74
 None
 1.02A 5jq7B-2r8rA:
undetectable		 5jq7B-2r8rA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v40 ADENYLOSUCCINATE
SYNTHETASE ISOZYME 2

(Homo sapiens) 		PF00709
(Adenylsucc_synt) 		4 LEU A 343
THR A 301
THR A 302
LEU A 436
 None
 0.90A 5jq7B-2v40A:
undetectable		 5jq7B-2v40A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvt GLUTAMATE RACEMASE

(Enterococcus
faecalis) 		PF01177
(Asp_Glu_race) 		4 LEU A 260
THR A 240
THR A 241
LEU A 255
 None
 0.78A 5jq7B-2vvtA:
undetectable		 5jq7B-2vvtA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvt GLUTAMATE RACEMASE

(Enterococcus
faecalis) 		PF01177
(Asp_Glu_race) 		4 TYR A 127
THR A 121
THR A  76
LEU A 181
 None
None
DGL  A1270 (-3.8A)
None
 1.13A 5jq7B-2vvtA:
undetectable		 5jq7B-2vvtA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4g NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Pseudomonas
aeruginosa) 		PF01370
(Epimerase) 		4 LEU A 250
THR A 193
THR A 192
LEU A 322
 None
 1.05A 5jq7B-2x4gA:
undetectable		 5jq7B-2x4gA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9e MYOSIN-2

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 LEU X 421
THR X 609
ASP X 605
LEU X 393
 None
 0.97A 5jq7B-2y9eX:
undetectable		 5jq7B-2y9eX:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2b SERINE
PALMITOYLTRANSFERASE

(Sphingobacterium
multivorum) 		PF00155
(Aminotran_1_2) 		4 LEU A 263
THR A 241
ASP A 211
LEU A 124
 None
PLP  A 400 (-3.8A)
None
None
 1.02A 5jq7B-3a2bA:
undetectable		 5jq7B-3a2bA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bit FACT COMPLEX SUBUNIT
SPT16

(Saccharomyces
cerevisiae) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		4 LEU A  18
TYR A  22
THR A 130
LEU A  51
 None
 1.13A 5jq7B-3bitA:
undetectable		 5jq7B-3bitA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzj UV ENDONUCLEASE

(Thermus
thermophilus) 		PF03851
(UvdE) 		4 LEU A 133
THR A  17
THR A  16
LEU A 130
 None
 0.81A 5jq7B-3bzjA:
undetectable		 5jq7B-3bzjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cio TYROSINE-PROTEIN
KINASE ETK

(Escherichia
coli) 		PF13614
(AAA_31) 		4 LEU A 587
THR A 648
THR A 537
LEU A 633
 None
 1.11A 5jq7B-3cioA:
undetectable		 5jq7B-3cioA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqf THIOL-ACTIVATED
CYTOLYSIN

(Bacillus
anthracis) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 LEU A 257
THR A 378
THR A 385
LEU A 142
 None
 0.77A 5jq7B-3cqfA:
undetectable		 5jq7B-3cqfA:
16.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3csy ENVELOPE
GLYCOPROTEIN GP2

(Zaire
ebolavirus) 		no annotation 5 LEU J 515
TYR J 517
THR J 519
THR J 520
LEU J 558
 None
 0.40A 5jq7B-3csyJ:
9.5		 5jq7B-3csyJ:
99.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dip ENOLASE

(unidentified) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 334
THR A 295
THR A  35
LEU A 109
 None
 1.11A 5jq7B-3dipA:
undetectable		 5jq7B-3dipA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ep1 PGRP-HD -
PEPTIDOGLYCAN
RECOGNITION PROTEIN
HOMOLOGUE

(Alvinella
pompejana) 		PF01510
(Amidase_2) 		4 LEU A 205
THR A 226
THR A 227
LEU A 201
 None
 1.12A 5jq7B-3ep1A:
undetectable		 5jq7B-3ep1A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fk2 GLUCOCORTICOID
RECEPTOR DNA-BINDING
FACTOR 1

(Homo sapiens) 		PF00620
(RhoGAP) 		4 LEU A1341
THR A1403
MET A1337
LEU A1361
 None
 1.07A 5jq7B-3fk2A:
undetectable		 5jq7B-3fk2A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g48 CHAPERONE CSAA

(Bacillus
anthracis) 		PF01588
(tRNA_bind) 		4 LEU A  58
TYR A  53
ASP A  92
LEU A  33
 None
EDO  A2001 ( 4.9A)
None
None
 1.14A 5jq7B-3g48A:
undetectable		 5jq7B-3g48A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Bos taurus) 		PF04869
(Uso1_p115_head) 		4 LEU A 458
THR A 500
ASP A 610
LEU A 474
 None
 1.10A 5jq7B-3gq2A:
undetectable		 5jq7B-3gq2A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lat BIFUNCTIONAL
AUTOLYSIN

(Staphylococcus
epidermidis) 		PF01510
(Amidase_2) 		4 LEU A 184
TYR A 183
THR A  62
LEU A 194
 None
 0.80A 5jq7B-3latA:
undetectable		 5jq7B-3latA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mv3 COATOMER SUBUNIT
EPSILON

(Saccharomyces
cerevisiae) 		PF04733
(Coatomer_E) 		4 LEU B  91
TYR B  90
THR B 122
LEU B  60
 None
 0.84A 5jq7B-3mv3B:
undetectable		 5jq7B-3mv3B:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1) 		no annotation 4 TYR B 164
THR B 351
THR B 346
LEU B 234
 None
 1.09A 5jq7B-3nwaB:
0.6		 5jq7B-3nwaB:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes) 		PF02350
(Epimerase_2) 		4 LEU A 194
TYR A 189
THR A 184
LEU A 202
 None
 1.03A 5jq7B-3ot5A:
undetectable		 5jq7B-3ot5A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pty ARABINOSYLTRANSFERAS
E C

(Mycobacterium
tuberculosis) 		PF14896
(Arabino_trans_C) 		4 LEU A 766
TYR A 869
MET A 765
LEU A 883
 None
 1.09A 5jq7B-3ptyA:
undetectable		 5jq7B-3ptyA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG

(Mus musculus) 		PF14674
(FANCI_S1-cap)
PF14675
(FANCI_S1)
PF14676
(FANCI_S2)
PF14677
(FANCI_S3)
PF14678
(FANCI_S4)
PF14679
(FANCI_HD1)
PF14680
(FANCI_HD2) 		4 LEU A 630
TYR A 634
ASP A 639
LEU A 667
 None
 0.80A 5jq7B-3s51A:
0.6		 5jq7B-3s51A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u3z MICROCEPHALIN

(Homo sapiens) 		PF00533
(BRCT)
PF16589
(BRCT_2) 		4 LEU A 781
THR A 683
THR A 649
LEU A 778
 None
 1.13A 5jq7B-3u3zA:
undetectable		 5jq7B-3u3zA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7g BIFUNCTIONAL
POLYNUCLEOTIDE
PHOSPHATASE/KINASE

(Mus musculus) 		PF08645
(PNK3P)
PF13671
(AAA_33) 		4 LEU A 202
THR A 322
ASP A 309
LEU A 242
 None
None
MG  A 529 ( 4.5A)
None
 1.04A 5jq7B-3u7gA:
undetectable		 5jq7B-3u7gA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1

(Rattus
norvegicus) 		no annotation 4 THR A  67
THR A  68
ASP A  47
LEU A 193
 None
 1.10A 5jq7B-3u9gA:
undetectable		 5jq7B-3u9gA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucq AMYLOSUCRASE

(Deinococcus
geothermalis) 		PF00128
(Alpha-amylase) 		4 LEU A 174
THR A 104
ASP A 151
LEU A 273
 None
 0.74A 5jq7B-3ucqA:
undetectable		 5jq7B-3ucqA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsv XYLOSIDASE

(Thermoanaerobacterium
saccharolyticum) 		PF13229
(Beta_helix) 		4 LEU A 142
TYR A 184
THR A 181
ASP A 177
 None
 1.06A 5jq7B-3vsvA:
undetectable		 5jq7B-3vsvA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsz RICIN B LECTIN

(Ruminiclostridium
thermocellum) 		PF04616
(Glyco_hydro_43)
PF14200
(RicinB_lectin_2) 		4 LEU A 205
TYR A 192
THR A 187
LEU A 222
 None
 1.06A 5jq7B-3vszA:
undetectable		 5jq7B-3vszA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zr8 AVR3A11

(Phytophthora
capsici) 		PF16810
(RXLR) 		4 LEU X 110
TYR X 122
THR X 127
ASP X 130
 None
 1.09A 5jq7B-3zr8X:
undetectable		 5jq7B-3zr8X:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 LEU A 230
THR A 259
THR A  55
ASP A  53
 None
 1.11A 5jq7B-3zs6A:
undetectable		 5jq7B-3zs6A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ap3 STEROID
MONOOXYGENASE

(Rhodococcus
rhodochrous) 		PF00743
(FMO-like) 		4 LEU A 385
TYR A 383
THR A 378
THR A 379
 None
 1.07A 5jq7B-4ap3A:
undetectable		 5jq7B-4ap3A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkx HISTONE DEACETYLASE
1
METASTASIS-ASSOCIATE
D PROTEIN MTA1

(Homo sapiens) 		PF00249
(Myb_DNA-binding)
PF00850
(Hist_deacetyl)
PF01448
(ELM2) 		4 TYR B 336
THR A 332
THR A 333
LEU B  41
 None
 1.12A 5jq7B-4bkxB:
undetectable		 5jq7B-4bkxB:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bug ANCILLARY PROTEIN 1

(Streptococcus
pyogenes) 		PF08341
(TED) 		4 LEU A 513
TYR A 516
THR A 519
THR A 467
 None
 1.14A 5jq7B-4bugA:
undetectable		 5jq7B-4bugA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bva THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE

(Mus musculus) 		PF02423
(OCD_Mu_crystall) 		4 LEU A 271
TYR A 246
THR A 287
THR A 286
 None
None
K  A1315 (-3.0A)
None
 0.86A 5jq7B-4bvaA:
undetectable		 5jq7B-4bvaA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cek REGULATOR OF
NONSENSE TRANSCRIPTS
2

(Homo sapiens) 		PF02854
(MIF4G) 		4 LEU A 673
ASP A 585
MET A 678
LEU A 640
 None
 1.09A 5jq7B-4cekA:
undetectable		 5jq7B-4cekA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ebz CHITIN ELICITOR
RECEPTOR KINASE 1

(Arabidopsis
thaliana) 		PF01476
(LysM) 		4 LEU A  51
TYR A 121
THR A 125
THR A 126
 None
None
NAG  A 805 (-4.6A)
NAG  A 805 ( 4.1A)
 1.02A 5jq7B-4ebzA:
undetectable		 5jq7B-4ebzA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fe4 XYLOSE OPERON
REGULATORY PROTEIN

(Escherichia
coli) 		PF12833
(HTH_18)
PF13377
(Peripla_BP_3) 		4 LEU A 365
TYR A 369
THR A 379
THR A 378
 None
 0.92A 5jq7B-4fe4A:
undetectable		 5jq7B-4fe4A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzi PROSTAGLANDIN F
SYNTHASE

(Trypanosoma
cruzi) 		PF00248
(Aldo_ket_red) 		4 LEU A 128
TYR A 108
THR A  77
THR A  49
 None
 1.10A 5jq7B-4fziA:
undetectable		 5jq7B-4fziA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4i 4-O-METHYL-GLUCURONO
YL METHYLESTERASE

(Thermothelomyces
thermophila) 		no annotation 4 LEU A  74
THR A 283
ASP A 249
LEU A 292
 None
 1.13A 5jq7B-4g4iA:
undetectable		 5jq7B-4g4iA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hse CHAPERONE PROTEIN
CLPB

(Thermus
thermophilus) 		PF00004
(AAA) 		4 LEU A 302
THR A 306
THR A 307
LEU A 291
 None
 1.11A 5jq7B-4hseA:
undetectable		 5jq7B-4hseA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knk BIFUNCTIONAL
AUTOLYSIN

(Staphylococcus
aureus) 		PF01510
(Amidase_2) 		4 LEU A 389
TYR A 388
THR A 267
LEU A 399
 None
 0.74A 5jq7B-4knkA:
undetectable		 5jq7B-4knkA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l3r UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		PF16139
(DUF4847) 		4 LEU A  43
THR A  47
THR A  48
LEU A  73
 None
 1.02A 5jq7B-4l3rA:
undetectable		 5jq7B-4l3rA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3z COPN

(Chlamydia
pneumoniae) 		PF07201
(HrpJ) 		4 LEU A 240
TYR A 207
THR A 178
LEU A 220
 None
 0.63A 5jq7B-4p3zA:
undetectable		 5jq7B-4p3zA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4g SHIKIMATE
5-DEHYDROGENASE AROE
(5-DEHYDROSHIKIMATE
REDUCTASE)

(Mycobacterium
tuberculosis) 		PF08501
(Shikimate_dh_N) 		4 LEU A 178
THR A 168
ASP A 143
LEU A 204
 BR  A 305 ( 4.8A)
None
None
None
 1.04A 5jq7B-4p4gA:
undetectable		 5jq7B-4p4gA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4per RIBONUCLEASE
INHIBITOR

(Gallus gallus) 		PF13516
(LRR_6) 		4 LEU A  87
THR A  27
ASP A   4
LEU A  63
 None
 1.13A 5jq7B-4perA:
undetectable		 5jq7B-4perA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfz 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE

(Mycolicibacterium
smegmatis) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 LEU A  72
THR A 269
THR A 263
LEU A  67
 None
 1.05A 5jq7B-4pfzA:
undetectable		 5jq7B-4pfzA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wep PUTATIVE
OSMOPROTECTANT
UPTAKE SYSTEM
SUBSTRATE-BINDING
PROTEIN OSMF

(Escherichia
coli) 		PF04069
(OpuAC) 		4 LEU A 154
TYR A 153
ASP A 137
LEU A 186
 None
 1.01A 5jq7B-4wepA:
undetectable		 5jq7B-4wepA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypv EST8

(Parvibaculum) 		PF07859
(Abhydrolase_3) 		4 LEU A  81
THR A  96
ASP A  42
LEU A 184
 None
 1.03A 5jq7B-4ypvA:
undetectable		 5jq7B-4ypvA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5

(Homo sapiens) 		PF12862
(ANAPC5) 		4 LEU O 567
TYR O 545
ASP O 517
LEU O 563
 None
 1.02A 5jq7B-5a31O:
undetectable		 5jq7B-5a31O:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0l MOEN5,DNA-BINDING
PROTEIN 7D

(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		no annotation 4 LEU A  59
THR A  46
THR A  47
LEU A  99
 None
 1.12A 5jq7B-5b0lA:
undetectable		 5jq7B-5b0lA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cer BD0816

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		4 LEU A 112
THR A 128
ASP A 130
LEU A 423
 None
 1.06A 5jq7B-5cerA:
undetectable		 5jq7B-5cerA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1x IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
P5 HEAVY CHAIN

(Homo sapiens;
Staphylococcus
aureus) 		PF05031
(NEAT)
PF07686
(V-set) 		4 LEU E 345
TYR C 100
THR C  97
ASP C 101
 None
 1.13A 5jq7B-5d1xE:
undetectable		 5jq7B-5d1xE:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ez3 ACYL-COA
DEHYDROGENASE

(Brucella
melitensis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M) 		4 LEU A 344
THR A 531
THR A 530
MET A 345
 None
 1.10A 5jq7B-5ez3A:
undetectable		 5jq7B-5ez3A:
15.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fhc ENVELOPE
GLYCOPROTEIN

(Zaire
ebolavirus) 		no annotation 4 LEU J 515
TYR J 517
MET J 548
LEU J 558
 None
 0.81A 5jq7B-5fhcJ:
9.4		 5jq7B-5fhcJ:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fhc ENVELOPE
GLYCOPROTEIN

(Zaire
ebolavirus) 		no annotation 5 LEU J 515
TYR J 517
THR J 519
THR J 520
LEU J 558
 None
 0.50A 5jq7B-5fhcJ:
9.4		 5jq7B-5fhcJ:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN

(Streptomyces
mobaraensis) 		no annotation 4 LEU A 341
THR A  24
THR A  25
ASP A  27
 None
GOL  A1348 (-4.5A)
GOL  A1348 (-3.0A)
None
 1.12A 5jq7B-5fzpA:
undetectable		 5jq7B-5fzpA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw8 HYPOTHETICAL
SECRETORY LIPASE
(FAMILY 3)

(Malassezia
globosa) 		PF01764
(Lipase_3) 		4 LEU A 178
THR A 232
ASP A 228
LEU A 220
 None
 1.04A 5jq7B-5gw8A:
undetectable		 5jq7B-5gw8A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h3h ABHYDROLASE
DOMAIN-CONTAINING
PROTEIN

(Exiguobacterium
antarcticum) 		PF00561
(Abhydrolase_1)
PF08386
(Abhydrolase_4) 		4 LEU A  44
TYR A  51
ASP A  55
LEU A 262
 None
 0.98A 5jq7B-5h3hA:
undetectable		 5jq7B-5h3hA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hp6 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF13385
(Laminin_G_3)
PF16369
(GH43_C) 		4 LEU A 775
THR A 722
ASP A 818
LEU A 714
 None
 0.97A 5jq7B-5hp6A:
undetectable		 5jq7B-5hp6A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hx9 BETA-LACTAMASE

(Burkholderia
vietnamiensis) 		PF13354
(Beta-lactamase2) 		4 LEU A  45
THR A 243
THR A 237
LEU A  37
 None
 1.11A 5jq7B-5hx9A:
undetectable		 5jq7B-5hx9A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i33 ADENYLOSUCCINATE
SYNTHETASE

(Cryptococcus
neoformans) 		PF00709
(Adenylsucc_synt) 		4 LEU A 317
THR A 275
THR A 276
LEU A 410
 None
 0.95A 5jq7B-5i33A:
undetectable		 5jq7B-5i33A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ig9 ATP GRASP LIGASE

(Microcystis
aeruginosa) 		no annotation 4 LEU A 113
TYR A 277
THR A 219
LEU A 321
 None
 1.13A 5jq7B-5ig9A:
undetectable		 5jq7B-5ig9A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihv BETA-LACTAMASE

(Burkholderia
ambifaria) 		PF13354
(Beta-lactamase2) 		4 LEU A  22
THR A 220
THR A 214
LEU A  14
 None
 1.08A 5jq7B-5ihvA:
undetectable		 5jq7B-5ihvA:
21.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jq3 ENVELOPE
GLYCOPROTEIN 2

(Zaire
ebolavirus) 		PF07921
(Fibritin_C) 		5 LEU B 515
TYR B 517
THR B 519
THR B 520
LEU B 558
 None
 0.42A 5jq7B-5jq3B:
12.7		 5jq7B-5jq3B:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ken EBOLA SURFACE
GLYCOPROTEIN, GP2

(Zaire
ebolavirus) 		no annotation 4 LEU B 515
TYR B 517
THR B 520
LEU B 558
 None
 0.80A 5jq7B-5kenB:
8.7		 5jq7B-5kenB:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ken EBOLA SURFACE
GLYCOPROTEIN, GP2

(Zaire
ebolavirus) 		no annotation 4 TYR B 517
THR B 519
THR B 520
LEU B 558
 None
 0.80A 5jq7B-5kenB:
8.7		 5jq7B-5kenB:
99.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kis RHS2

(Yersinia
entomophaga) 		no annotation 4 LEU B 595
THR B 619
THR B 396
LEU B 329
 None
 1.06A 5jq7B-5kisB:
undetectable		 5jq7B-5kisB:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22

(Homo sapiens) 		no annotation 4 LEU A 208
TYR A 225
THR A 129
ASP A 132
 None
 0.98A 5jq7B-5lf9A:
0.2		 5jq7B-5lf9A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nii THIOREDOXIN
REDUCTASE

(Desulfovibrio
vulgaris) 		no annotation 4 LEU A 201
THR A 171
ASP A 194
LEU A 207
 None
 1.06A 5jq7B-5niiA:
undetectable		 5jq7B-5niiA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sz8 HEMOLYSIN

(Proteus
mirabilis) 		PF05860
(Haemagg_act) 		4 LEU A 183
THR A 190
THR A 191
LEU A 181
 None
 1.05A 5jq7B-5sz8A:
undetectable		 5jq7B-5sz8A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve9 MICROTUBULE-ACTIN
CROSS-LINKING FACTOR
1, ISOFORMS 1/2/3/5

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 THR A7077
THR A7078
MET A7039
LEU A7106
 None
 0.98A 5jq7B-5ve9A:
undetectable		 5jq7B-5ve9A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgj 1FD6-V1V2-WITO

(Human
immunodeficiency
virus 1) 		PF00516
(GP120)
PF01378
(IgG_binding_B) 		4 LEU G 129
THR G 161
THR G 162
LEU G 193
 None
 1.13A 5jq7B-5vgjG:
undetectable		 5jq7B-5vgjG:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vo5 COILED-COIL AND C2
DOMAIN-CONTAINING
PROTEIN
1-LIKE,GH13992P

(Drosophila
melanogaster) 		PF03357
(Snf7) 		4 LEU A   8
TYR A  48
MET A   4
LEU A  59
 None
 1.05A 5jq7B-5vo5A:
undetectable		 5jq7B-5vo5A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wvg CHITINASE

(Ostrinia
furnacalis) 		no annotation 4 LEU A 890
THR A 559
MET A 886
LEU A 853
 None
 1.14A 5jq7B-5wvgA:
undetectable		 5jq7B-5wvgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8j THYMIDYLATE KINASE

(Thermus
thermophilus) 		no annotation 4 LEU A  81
THR A   7
ASP A  94
LEU A  78
 None
 0.97A 5jq7B-5x8jA:
undetectable		 5jq7B-5x8jA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywp JEV E PROTEIN

(Japanese
encephalitis
virus) 		no annotation 4 LEU A 289
THR A  40
THR A 356
LEU A  23
 None
 1.11A 5jq7B-5ywpA:
undetectable		 5jq7B-5ywpA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zqe -

(-) 		no annotation 4 LEU A 249
THR A 226
ASP A 161
LEU A 174
 None
CES  A 301 (-4.4A)
None
None
 0.86A 5jq7B-5zqeA:
undetectable		 5jq7B-5zqeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egt GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		no annotation 4 THR A 984
THR A 989
ASP A 987
LEU A1114
 None
 1.09A 5jq7B-6egtA:
undetectable		 5jq7B-6egtA:
15.12