SIMILAR PATTERNS OF AMINO ACIDS FOR 5JMN_B_FUAB1101_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brw PROTEIN (PYRIMIDINE
NUCLEOSIDE
PHOSPHORYLASE)

(Geobacillus
stearothermophilus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 ILE A 236
LEU A 275
LYS A  81
HIS A  82
 None
None
PO4  A2001 ( 2.6A)
PO4  A2001 (-4.1A)
 1.21A 5jmnB-1brwA:
0.0		 5jmnB-1brwA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dk5 ANNEXIN 24(CA32)

(Capsicum annuum) 		PF00191
(Annexin) 		4 ILE A 285
LEU A 313
HIS A 269
VAL A 255
 None
None
SO4  A 809 (-3.9A)
None
 1.03A 5jmnB-1dk5A:
undetectable		 5jmnB-1dk5A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ece ENDOCELLULASE E1

(Acidothermus
cellulolyticus) 		PF00150
(Cellulase) 		4 ILE A  61
LEU A 332
HIS A  39
VAL A  38
 None
 1.19A 5jmnB-1eceA:
0.1		 5jmnB-1eceA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j32 ASPARTATE
AMINOTRANSFERASE

(Phormidium
lapideum) 		PF00155
(Aminotran_1_2) 		4 ILE A 208
LEU A 304
LYS A 317
VAL A 179
 None
 1.22A 5jmnB-1j32A:
0.0		 5jmnB-1j32A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhj APC10

(Homo sapiens) 		PF03256
(ANAPC10) 		4 ILE A 120
LEU A  45
HIS A  62
VAL A 141
 None
 0.95A 5jmnB-1jhjA:
0.0		 5jmnB-1jhjA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k0k PROFILIN

(Saccharomyces
cerevisiae) 		PF00235
(Profilin) 		4 ILE A  45
LYS A  17
HIS A  99
VAL A  86
 None
 1.08A 5jmnB-1k0kA:
0.1		 5jmnB-1k0kA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs1 ADP-RIBOSYLTRANSFERA
SE

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		4 ILE A 153
LYS A 263
HIS A 241
VAL A 242
 None
 1.21A 5jmnB-1qs1A:
0.0		 5jmnB-1qs1A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs2 ADP-RIBOSYLTRANSFERA
SE

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		4 ILE A 153
LYS A 263
HIS A 241
VAL A 242
 None
 1.19A 5jmnB-1qs2A:
0.0		 5jmnB-1qs2A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ral 3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		4 ILE A 144
LEU A 182
LYS A 185
VAL A 165
 None
 1.15A 5jmnB-1ralA:
0.0		 5jmnB-1ralA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rj6 CARBONIC ANHYDRASE
XIV

(Mus musculus) 		PF00194
(Carb_anhydrase) 		4 ILE A 167
LEU A  95
HIS A 159
VAL A 176
 None
 1.24A 5jmnB-1rj6A:
undetectable		 5jmnB-1rj6A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryn PROTEIN CRS2

(Zea mays) 		PF01195
(Pept_tRNA_hydro) 		4 ILE A  32
LEU A  60
HIS A  88
VAL A 177
 ILE  A  32 ( 0.6A)
LEU  A  60 ( 0.6A)
HIS  A  88 ( 1.0A)
VAL  A 177 ( 0.5A)
 1.24A 5jmnB-1rynA:
undetectable		 5jmnB-1rynA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vq7 50S RIBOSOMAL
PROTEIN L30P

(Haloarcula
marismortui) 		PF00327
(Ribosomal_L30) 		4 ILE W  26
LEU W 150
HIS W   2
VAL W  35
 None
 1.10A 5jmnB-1vq7W:
undetectable		 5jmnB-1vq7W:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrp CREATINE KINASE, M
CHAIN

(Tetronarce
californica) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ILE A  38
LEU A  23
HIS A  29
VAL A  92
 None
 1.20A 5jmnB-1vrpA:
2.4		 5jmnB-1vrpA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfl THIOREDOXIN H1

(Arabidopsis
thaliana) 		PF00085
(Thioredoxin) 		4 ILE A 109
LEU A  94
LYS A  89
VAL A  60
 None
 1.19A 5jmnB-1xflA:
undetectable		 5jmnB-1xflA:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xov PLY PROTEIN

(Listeria virus
PSA) 		PF01520
(Amidase_3) 		4 ILE A 106
LEU A  31
HIS A  75
VAL A  74
 None
 1.19A 5jmnB-1xovA:
undetectable		 5jmnB-1xovA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1

(Rattus
norvegicus) 		PF00595
(PDZ) 		4 ILE A 702
LEU A 632
HIS A 663
VAL A 599
 None
 1.12A 5jmnB-1zubA:
undetectable		 5jmnB-1zubA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ak3 ADENYLATE KINASE
ISOENZYME-3

(Bos taurus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 ILE A  10
LEU A   6
LYS A 213
VAL A 206
 None
 1.14A 5jmnB-2ak3A:
undetectable		 5jmnB-2ak3A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 ILE A 417
LEU A 253
HIS A 299
VAL A 295
 None
 1.23A 5jmnB-2bg9A:
2.1		 5jmnB-2bg9A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5k UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF01704
(UDPGP) 		4 ILE A 479
LEU A 394
HIS A 448
VAL A 467
 None
 1.11A 5jmnB-2i5kA:
undetectable		 5jmnB-2i5kA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7q MCMV TEGUMENT
PROTEIN M48 ENCODED
UBIQUITIN- SPECIFIC
PROTEASE, M48USP

(Murid
betaherpesvirus
1) 		PF04843
(Herpes_teg_N) 		4 ILE A 146
LEU A  36
HIS A  95
VAL A 198
 None
 0.99A 5jmnB-2j7qA:
undetectable		 5jmnB-2j7qA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oas 4-HYDROXYBUTYRATE
COENZYME A
TRANSFERASE

(Shewanella
oneidensis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 ILE A 193
LEU A 404
HIS A 381
VAL A 348
 None
 1.15A 5jmnB-2oasA:
undetectable		 5jmnB-2oasA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1

(Homo sapiens) 		PF02580
(Tyr_Deacylase) 		4 ILE A  33
LEU A 145
LYS A  48
HIS A  44
 None
 1.00A 5jmnB-2okvA:
undetectable		 5jmnB-2okvA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p6r AFUHEL308 HELICASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 ILE A 637
LEU A 669
LYS A 665
HIS A 662
 None
 1.16A 5jmnB-2p6rA:
undetectable		 5jmnB-2p6rA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pie E3 UBIQUITIN-PROTEIN
LIGASE RNF8

(Homo sapiens) 		PF00498
(FHA) 		4 ILE A 100
LEU A  30
HIS A  63
VAL A  85
 None
 1.18A 5jmnB-2pieA:
undetectable		 5jmnB-2pieA:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rrf ZINC FINGER FYVE
DOMAIN-CONTAINING
PROTEIN 21

(Homo sapiens) 		PF16696
(ZFYVE21_C) 		4 ILE A  58
LEU A  18
HIS A 123
VAL A  66
 None
 1.21A 5jmnB-2rrfA:
undetectable		 5jmnB-2rrfA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE

(Arabidopsis
thaliana) 		PF00201
(UDPGT) 		4 ILE A  11
LEU A 242
HIS A  32
VAL A  31
 None
 1.20A 5jmnB-2vg8A:
undetectable		 5jmnB-2vg8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xal INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Arabidopsis
thaliana) 		PF06090
(Ins_P5_2-kin) 		4 ILE A 167
LEU A 408
HIS A 101
VAL A 300
 None
 1.16A 5jmnB-2xalA:
undetectable		 5jmnB-2xalA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf4 HYDROXYACYLGLUTATHIO
NE HYDROLASE

(Salmonella
enterica) 		PF00753
(Lactamase_B) 		4 ILE A  77
LEU A  87
HIS A 136
VAL A 137
 None
 1.21A 5jmnB-2xf4A:
undetectable		 5jmnB-2xf4A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1k (NEO)PULLULANASE

(Thermus
thermophilus) 		PF00128
(Alpha-amylase) 		4 ILE A  12
LEU A  60
HIS A 107
VAL A 113
 None
 1.16A 5jmnB-2z1kA:
undetectable		 5jmnB-2z1kA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a6p EXPORTIN-5

(Homo sapiens) 		PF08389
(Xpo1) 		4 ILE A 273
LEU A 251
HIS A 242
VAL A 238
 None
 1.23A 5jmnB-3a6pA:
undetectable		 5jmnB-3a6pA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axx 458AA LONG
HYPOTHETICAL
ENDO-1,4-BETA-GLUCAN
ASE

(Pyrococcus
horikoshii) 		PF00150
(Cellulase) 		4 ILE A 101
LEU A 390
HIS A  79
VAL A  78
 None
 1.18A 5jmnB-3axxA:
undetectable		 5jmnB-3axxA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1j GLYCOGEN SYNTHASE

(Escherichia
coli) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		4 ILE A  47
LEU A  19
HIS A   5
VAL A  39
 None
 1.22A 5jmnB-3d1jA:
undetectable		 5jmnB-3d1jA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f4m TUMOR NECROSIS
FACTOR,
ALPHA-INDUCED
PROTEIN 8-LIKE
PROTEIN 2

(Homo sapiens) 		PF05527
(DUF758) 		4 ILE A 143
LEU A  94
HIS A  74
VAL A  70
 None
 1.22A 5jmnB-3f4mA:
undetectable		 5jmnB-3f4mA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7k AGMATINE DEIMINASE

(Arabidopsis
thaliana) 		PF04371
(PAD_porph) 		4 ILE A 100
LEU A 161
HIS A 167
VAL A 168
 None
 1.14A 5jmnB-3h7kA:
undetectable		 5jmnB-3h7kA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7v O-SUCCINYLBENZOATE
SYNTHASE

(Thermosynechococcus
elongatus) 		PF13378
(MR_MLE_C) 		4 ILE A  78
LEU A  33
LYS A   1
HIS A  69
 None
 1.20A 5jmnB-3h7vA:
undetectable		 5jmnB-3h7vA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN HEAVY CHAIN
ISOFORM A

(Doryteuthis
pealeii) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF02736
(Myosin_N) 		4 ILE A 535
LEU A 559
LYS A 567
HIS A 579
 None
 1.24A 5jmnB-3i5gA:
undetectable		 5jmnB-3i5gA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j81 US2

(Kluyveromyces
lactis) 		PF00318
(Ribosomal_S2) 		4 ILE A 160
LEU A   9
HIS A  23
VAL A  22
 None
 1.22A 5jmnB-3j81A:
undetectable		 5jmnB-3j81A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A  89
LEU A  78
HIS A 154
VAL A 103
 None
PGE  A 612 (-4.8A)
None
None
 1.16A 5jmnB-3kw8A:
undetectable		 5jmnB-3kw8A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kys TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-1

(Homo sapiens) 		no annotation 4 ILE A 372
LEU A 203
HIS A 226
VAL A 225
 BME  A 700 ( 4.9A)
None
None
None
 1.24A 5jmnB-3kysA:
undetectable		 5jmnB-3kysA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m65 ATP-DEPENDENT
PROTEASE LA 1

(Bacillus
subtilis) 		PF02190
(LON_substr_bdg) 		4 ILE A  48
LEU A  17
HIS A  26
VAL A  88
 None
 1.04A 5jmnB-3m65A:
2.3		 5jmnB-3m65A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtj HOMOSERINE
DEHYDROGENASE

(Thiobacillus
denitrificans) 		PF00742
(Homoserine_dh)
PF01842
(ACT)
PF03447
(NAD_binding_3) 		4 ILE A 157
LEU A 165
HIS A 263
VAL A 262
 None
 1.24A 5jmnB-3mtjA:
2.5		 5jmnB-3mtjA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mw2 NEUREXIN-1-ALPHA

(Mus musculus) 		PF02210
(Laminin_G_2) 		4 ILE A 244
LEU A 113
HIS A 142
VAL A 125
 None
 1.02A 5jmnB-3mw2A:
undetectable		 5jmnB-3mw2A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p5s CD38 MOLECULE

(Bos taurus) 		PF02267
(Rib_hydrolayse) 		4 ILE A 249
LEU A 204
LYS A 120
VAL A 198
 None
NAG  A 501 ( 4.9A)
AVU  A 280 ( 2.5A)
None
 1.14A 5jmnB-3p5sA:
undetectable		 5jmnB-3p5sA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poy NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 ILE A1306
LEU A1175
HIS A1204
VAL A1187
 None
 0.87A 5jmnB-3poyA:
undetectable		 5jmnB-3poyA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tbb SMALL LACCASE,
OXIDOREDUCTASE

(Streptomyces
viridosporus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A  84
LEU A  73
HIS A 149
VAL A  98
 None
 1.17A 5jmnB-3tbbA:
undetectable		 5jmnB-3tbbA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vus POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Escherichia
coli) 		PF01522
(Polysacc_deac_1) 		4 ILE A  91
LEU A 237
HIS A 184
VAL A 249
 None
None
ZN  A 401 ( 3.4A)
None
 1.06A 5jmnB-3vusA:
undetectable		 5jmnB-3vusA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6m 458AA LONG
HYPOTHETICAL
ENDO-1,4-BETA-GLUCAN
ASE

(Pyrococcus
horikoshii) 		PF00150
(Cellulase) 		4 ILE A 101
LEU A 390
HIS A  79
VAL A  78
 None
 1.20A 5jmnB-3w6mA:
undetectable		 5jmnB-3w6mA:
18.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B

(Escherichia
coli) 		PF00873
(ACR_tran) 		4 LEU A 300
LYS A 334
HIS A 338
VAL A 341
 None
 0.96A 5jmnB-3w9hA:
60.0		 5jmnB-3w9hA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus;
Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 ILE A 696
LEU A 682
HIS A 692
VAL A 777
 None
 1.05A 5jmnB-3waiA:
undetectable		 5jmnB-3waiA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wcs ERYTHROAGGLUTININ

(Phaseolus
vulgaris) 		PF00139
(Lectin_legB) 		4 ILE A 171
LEU A 129
HIS A 140
VAL A 221
 None
 0.86A 5jmnB-3wcsA:
undetectable		 5jmnB-3wcsA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbq PHIKZ039

(Pseudomonas
virus phiKZ) 		no annotation 4 ILE A   9
LEU A  22
HIS A 167
VAL A 130
 None
 1.19A 5jmnB-3zbqA:
undetectable		 5jmnB-3zbqA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 ILE A 421
LEU A 312
HIS A 441
VAL A 202
 None
 1.14A 5jmnB-4bjuA:
2.0		 5jmnB-4bjuA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4boo ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 ILE A 417
LEU A 253
HIS A 299
VAL A 295
 None
 1.23A 5jmnB-4booA:
2.1		 5jmnB-4booA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cti OSMOLARITY SENSOR
PROTEIN ENVZ, AF1503

(Archaeoglobus
fulgidus;
Escherichia
coli) 		PF00512
(HisKA)
PF00672
(HAMP)
PF02518
(HATPase_c) 		4 ILE A 531
LEU A 404
HIS A 515
VAL A 512
 None
 1.21A 5jmnB-4ctiA:
2.8		 5jmnB-4ctiA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw4 BETA-KETOACYL
SYNTHASE

(Pseudomonas
aeruginosa) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 ILE A 304
LEU A 482
HIS A 381
VAL A   8
 None
 1.19A 5jmnB-4cw4A:
2.6		 5jmnB-4cw4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dx8 KREV INTERACTION
TRAPPED PROTEIN 1

(Homo sapiens) 		PF16705
(NUDIX_5) 		4 ILE H 158
LEU H  37
LYS H  51
HIS H 148
 None
 1.01A 5jmnB-4dx8H:
undetectable		 5jmnB-4dx8H:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE

(Pseudomonas
putida) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 ILE A 341
LEU A 307
HIS A 291
VAL A 290
 None
 1.11A 5jmnB-4dyjA:
undetectable		 5jmnB-4dyjA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4et7 EPHRIN TYPE-A
RECEPTOR 5

(Homo sapiens) 		PF01404
(Ephrin_lbd) 		4 ILE A 118
LEU A 113
HIS A  97
VAL A  69
 None
 1.16A 5jmnB-4et7A:
undetectable		 5jmnB-4et7A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f99 CELL DIVISION CYCLE
7-RELATED PROTEIN
KINASE
PROTEIN DBF4 HOMOLOG
A

(Homo sapiens) 		PF00069
(Pkinase)
PF07535
(zf-DBF) 		4 ILE B 330
LEU A  92
LYS A  90
VAL A 120
 None
None
ADP  A 601 (-2.6A)
None
 1.04A 5jmnB-4f99B:
undetectable		 5jmnB-4f99B:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f9d POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Escherichia
coli) 		PF01522
(Polysacc_deac_1)
PF14883
(GHL13) 		4 ILE A  91
LEU A 237
HIS A 184
VAL A 249
 None
None
NI  A 701 ( 3.4A)
None
 1.06A 5jmnB-4f9dA:
0.4		 5jmnB-4f9dA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fin ETTA (YJJK) ABCF
FAMILY PROTEIN

(Escherichia
coli) 		PF00005
(ABC_tran)
PF12848
(ABC_tran_Xtn) 		4 ILE A 313
LEU A 475
HIS A 454
VAL A 391
 None
 1.22A 5jmnB-4finA:
0.0		 5jmnB-4finA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4giw RUN AND SH3
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF02759
(RUN) 		4 ILE A 124
LEU A  50
LYS A  21
VAL A  15
 None
 1.14A 5jmnB-4giwA:
undetectable		 5jmnB-4giwA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyb COPPER OXIDASE

(Streptomyces
lividans) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A  89
LEU A  78
HIS A 154
VAL A 103
 None
PGE  A 409 (-4.9A)
None
None
 1.20A 5jmnB-4gybA:
undetectable		 5jmnB-4gybA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 ILE A 220
LEU A 459
HIS A 440
VAL A 183
 None
 1.23A 5jmnB-4gysA:
undetectable		 5jmnB-4gysA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3o LECTIN

(Allium sativum) 		PF01453
(B_lectin) 		4 ILE A  88
LEU A  10
HIS A  22
VAL A  18
 None
 1.19A 5jmnB-4h3oA:
undetectable		 5jmnB-4h3oA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hlj ROUNDABOUT HOMOLOG 1

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A 826
LEU A 871
LYS A 786
VAL A 838
 None
 1.24A 5jmnB-4hljA:
undetectable		 5jmnB-4hljA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN

(Pseudomonas) 		PF01804
(Penicil_amidase) 		4 ILE B 189
LEU B 166
HIS B  60
VAL B 477
 None
 1.19A 5jmnB-4hstB:
undetectable		 5jmnB-4hstB:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j4b PYLD

(Methanosarcina
barkeri) 		no annotation 4 ILE A  59
LEU A 247
HIS A  68
VAL A  80
 0TF  A 904 (-4.3A)
0TF  A 904 ( 4.5A)
None
None
 0.82A 5jmnB-4j4bA:
undetectable		 5jmnB-4j4bA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhp X-LINKED RETINITIS
PIGMENTOSA GTPASE
REGULATOR

(Homo sapiens) 		PF00415
(RCC1) 		4 ILE C 292
LEU C 280
HIS C 254
VAL C 256
 None
 1.10A 5jmnB-4jhpC:
undetectable		 5jmnB-4jhpC:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbx UNCHARACTERIZED
PROTEIN YHFX

(Escherichia
coli) 		PF01168
(Ala_racemase_N) 		4 ILE A 317
LEU A 336
HIS A 306
VAL A   3
 LLP  A   7 (-3.5A)
None
ACE  A   0 ( 4.0A)
ACE  A   0 ( 3.9A)
 1.15A 5jmnB-4kbxA:
undetectable		 5jmnB-4kbxA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kma GM14141P

(Drosophila
melanogaster) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		4 LEU A 115
LYS A 110
HIS A  71
VAL A  68
 None
 1.21A 5jmnB-4kmaA:
undetectable		 5jmnB-4kmaA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lkb HYPOTHETICAL PROTEIN
ALR4568/PUTATIVE
4-OXALOCROTONATE
TAUTOMERASE

(Nostoc sp. PCC
7120) 		no annotation 4 ILE F  99
LEU F  80
HIS F  41
VAL F   6
 None
 1.24A 5jmnB-4lkbF:
2.4		 5jmnB-4lkbF:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5a PROTEIN EFR3

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 363
LEU A 214
LYS A 280
VAL A 327
 None
 1.15A 5jmnB-4n5aA:
2.3		 5jmnB-4n5aA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rap GLYCOSYLTRANSFERASE
TIBC

(Escherichia
coli) 		PF01075
(Glyco_transf_9) 		4 ILE A 317
LEU A 386
HIS A 244
VAL A 241
 None
 1.18A 5jmnB-4rapA:
undetectable		 5jmnB-4rapA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv6 2-DEHYDRO-3-DEOXYGLU
CARATE ALDOLASE

(Staphylococcus
aureus) 		PF03328
(HpcH_HpaI) 		4 ILE A 150
LYS A 209
HIS A 207
VAL A 203
 None
 1.17A 5jmnB-4tv6A:
undetectable		 5jmnB-4tv6A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w1t COPPER OXIDASE

(Streptomyces
sviceus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A  86
LEU A  75
HIS A 151
VAL A 100
 None
 1.19A 5jmnB-4w1tA:
undetectable		 5jmnB-4w1tA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzb NITROGENASE IRON
PROTEIN 1

(Azotobacter
vinelandii) 		PF00142
(Fer4_NifH) 		4 ILE E 106
LEU E  76
LYS E  84
VAL E 122
 None
 1.20A 5jmnB-4wzbE:
undetectable		 5jmnB-4wzbE:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7i MYOTUBULARIN-RELATED
PROTEIN 8

(Homo sapiens) 		PF06602
(Myotub-related) 		4 ILE A 375
LEU A 366
HIS A 428
VAL A 431
 None
 0.98A 5jmnB-4y7iA:
1.3		 5jmnB-4y7iA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7i MYOTUBULARIN-RELATED
PROTEIN 8

(Homo sapiens) 		PF06602
(Myotub-related) 		4 ILE A 375
LEU A 403
HIS A 430
VAL A 459
 None
 0.93A 5jmnB-4y7iA:
1.3		 5jmnB-4y7iA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ady GTPASE HFLX

(Escherichia
coli) 		PF01926
(MMR_HSR1)
PF13167
(GTP-bdg_N)
PF16360
(GTP-bdg_M) 		4 ILE 6 217
LEU 6 279
HIS 6 282
VAL 6 283
 None
 1.14A 5jmnB-5ady6:
undetectable		 5jmnB-5ady6:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b16 RIBONUCLEASE
3,DROSHA,RIBONUCLEAS
E
3,DROSHA,RIBONUCLEAS
E 3

(Homo sapiens) 		PF00035
(dsrm)
PF00636
(Ribonuclease_3)
PF14622
(Ribonucleas_3_3) 		4 ILE A 625
LEU A 917
HIS A 859
VAL A 578
 None
 0.95A 5jmnB-5b16A:
2.1		 5jmnB-5b16A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm2 TRNA
METHYLTRANSFERASE
TRNA
METHYLTRANSFERASE
ACTIVATOR SUBUNIT

(Yarrowia
lipolytica) 		PF03966
(Trm112p)
PF08241
(Methyltransf_11) 		4 ILE M 115
LEU M 123
HIS Z 111
VAL M   9
 None
 1.22A 5jmnB-5cm2M:
undetectable		 5jmnB-5cm2M:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyu CONSERVED MEMBRANE
PROTEIN

(Mycolicibacterium
smegmatis) 		PF05108
(T7SS_ESX1_EccB) 		4 ILE A 249
LEU A 264
HIS A 280
VAL A 291
 None
 0.96A 5jmnB-5cyuA:
undetectable		 5jmnB-5cyuA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5emw TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-5

(Homo sapiens) 		no annotation 4 ILE A 399
LEU A 230
HIS A 253
VAL A 252
 None
 1.20A 5jmnB-5emwA:
undetectable		 5jmnB-5emwA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j07 SUPEROXIDE DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE [CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 ILE A   7
LEU A  90
HIS A  32
VAL A  46
 None
 1.11A 5jmnB-5j07A:
undetectable		 5jmnB-5j07A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0c SUPEROXIDE DISMUTASE
[CU-ZN],SUPEROXIDE
DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 ILE A 106
LEU A  75
HIS A  17
VAL A  31
 None
 1.07A 5jmnB-5j0cA:
undetectable		 5jmnB-5j0cA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 ILE A  82
LEU A  51
HIS A 107
VAL A   7
 None
 1.15A 5jmnB-5j0fA:
undetectable		 5jmnB-5j0fA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0g OXIDOREDUCTASE,SUPER
OXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 ILE A  36
LEU A   5
HIS A  61
VAL A  75
 None
 1.13A 5jmnB-5j0gA:
undetectable		 5jmnB-5j0gA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jtv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7

(Homo sapiens) 		PF00443
(UCH)
PF14533
(USP7_C2) 		4 ILE A 320
LEU A 228
HIS A 451
VAL A 401
 None
 1.23A 5jmnB-5jtvA:
undetectable		 5jmnB-5jtvA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3x NEGATIVE ELONGATION
FACTOR A
NEGATIVE ELONGATION
FACTOR C/D

(Homo sapiens) 		PF04858
(TH1)
no annotation 		4 ILE B 418
LEU A 178
HIS B 451
VAL B 431
 None
 1.21A 5jmnB-5l3xB:
3.7		 5jmnB-5l3xB:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6m RIBONUCLEASE VAPC
VAPB FAMILY PROTEIN

(Caulobacter
vibrioides) 		PF01850
(PIN)
PF04014
(MazE_antitoxin) 		4 ILE B  31
LEU A  56
HIS B  12
VAL B   9
 MLI  A 101 (-4.3A)
None
None
None
 1.20A 5jmnB-5l6mB:
undetectable		 5jmnB-5l6mB:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nge UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7

(Homo sapiens) 		no annotation 4 ILE A 320
LEU A 228
HIS A 451
VAL A 401
 None
 1.24A 5jmnB-5ngeA:
undetectable		 5jmnB-5ngeA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tz6 CURJ

(Moorea
producens) 		PF14765
(PS-DH) 		4 ILE A 949
LEU A 975
HIS A1071
VAL A1044
 None
 1.18A 5jmnB-5tz6A:
undetectable		 5jmnB-5tz6A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uto EDD DOMAIN PROTEIN,
DEGV FAMILY

(Staphylococcus
aureus) 		no annotation 4 ILE A 233
LEU A 191
HIS A 270
VAL A 267
 PLM  A 301 (-4.1A)
None
PLM  A 301 (-3.5A)
PLM  A 301 (-4.3A)
 1.19A 5jmnB-5utoA:
undetectable		 5jmnB-5utoA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA

(Pseudomonas
aeruginosa) 		PF16957
(Mal_decarbox_Al) 		4 ILE A 268
LEU A 517
HIS A 461
VAL A 418
 None
 1.00A 5jmnB-5vj1A:
undetectable		 5jmnB-5vj1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vzj EXOSOME COMPLEX
EXONUCLEASE RRP6

(Saccharomyces
cerevisiae) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		4 ILE J 297
LEU J 152
LYS J 155
VAL J 309
 None
 0.98A 5jmnB-5vzjJ:
undetectable		 5jmnB-5vzjJ:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wmm NRPS

(Micromonospora
sp. ML1) 		no annotation 4 ILE A 137
LEU A 131
HIS A  86
VAL A  82
 None
 1.11A 5jmnB-5wmmA:
2.1		 5jmnB-5wmmA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yu1 LYSINE
CYCLODEAMINASE

(Streptomyces
pristinaespiralis) 		no annotation 4 ILE A 198
LEU A 247
HIS A 229
VAL A 204
 None
 1.17A 5jmnB-5yu1A:
undetectable		 5jmnB-5yu1A:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6apj ALPHA-N-ACETYLGALACT
OSAMINIDE
ALPHA-2,6-SIALYLTRAN
SFERASE 2

(Homo sapiens) 		no annotation 4 ILE A 183
LEU A 160
HIS A 172
VAL A 175
 None
 1.22A 5jmnB-6apjA:
undetectable		 5jmnB-6apjA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axg RAS GUANYL-RELEASING
PROTEIN 4

(Homo sapiens) 		no annotation 4 ILE A 146
LEU A 124
HIS A 132
VAL A 135
 None
 1.21A 5jmnB-6axgA:
2.4		 5jmnB-6axgA:
18.29