SIMILAR PATTERNS OF AMINO ACIDS FOR 5JH7_D_6K9D502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ak2 ADENYLATE KINASE
ISOENZYME-2


(Bos taurus)
PF00406
(ADK)
PF05191
(ADK_lid)
5 VAL A 126
SER A 125
ASP A 124
PRO A 103
LEU A  22
None
1.09A 5jh7D-1ak2A:
3.3
5jh7D-1ak2A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amk TRIOSE PHOSPHATE
ISOMERASE


(Leishmania
mexicana)
PF00121
(TIM)
5 GLN A 182
VAL A 214
SER A 213
THR A 174
TYR A 210
None
None
PGA  A 600 (-4.2A)
None
None
1.42A 5jh7D-1amkA:
undetectable
5jh7D-1amkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amk TRIOSE PHOSPHATE
ISOMERASE


(Leishmania
mexicana)
PF00121
(TIM)
5 VAL A 214
SER A 213
THR A 174
TYR A 210
LEU A 222
None
PGA  A 600 (-4.2A)
None
None
None
1.26A 5jh7D-1amkA:
undetectable
5jh7D-1amkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1att ANTITHROMBIN III

(Bos taurus)
PF00079
(Serpin)
5 ASN A 209
VAL A 365
SER A 366
ASP A 367
LEU A 352
None
1.39A 5jh7D-1attA:
undetectable
5jh7D-1attA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h54 MALTOSE
PHOSPHORYLASE


(Lactobacillus
brevis)
PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N)
5 GLN A 387
ASP A 359
THR A 360
GLU A 361
LEU A 404
None
1.14A 5jh7D-1h54A:
undetectable
5jh7D-1h54A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lc7 L-THREONINE-O-3-PHOS
PHATE DECARBOXYLASE


(Salmonella
enterica)
PF00155
(Aminotran_1_2)
5 VAL A 248
SER A 247
GLU A  87
TYR A  61
LEU A  64
None
1.25A 5jh7D-1lc7A:
2.3
5jh7D-1lc7A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mo0 TRIOSEPHOSPHATE
ISOMERASE


(Caenorhabditis
elegans)
PF00121
(TIM)
5 VAL A 211
SER A 210
THR A 171
TYR A 207
LEU A 219
None
SO4  A 901 (-3.7A)
None
None
None
1.38A 5jh7D-1mo0A:
undetectable
5jh7D-1mo0A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2e EXOCELLOBIOHYDROLASE
I


(Trichoderma
reesei)
PF00840
(Glyco_hydro_7)
5 GLN A 186
ASP A 150
TYR A 171
PRO A 177
LEU A 180
None
1.16A 5jh7D-1q2eA:
undetectable
5jh7D-1q2eA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcd TRIOSEPHOSPHATE
ISOMERASE


(Trypanosoma
cruzi)
PF00121
(TIM)
5 GLN A 183
VAL A 215
SER A 214
THR A 175
TYR A 211
None
1.47A 5jh7D-1tcdA:
undetectable
5jh7D-1tcdA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcd TRIOSEPHOSPHATE
ISOMERASE


(Trypanosoma
cruzi)
PF00121
(TIM)
5 VAL A 215
SER A 214
THR A 175
TYR A 211
LEU A 223
None
1.39A 5jh7D-1tcdA:
undetectable
5jh7D-1tcdA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wd3 ALPHA-L-ARABINOFURAN
OSIDASE B


(Aspergillus
kawachii)
PF05270
(AbfB)
PF09206
(ArabFuran-catal)
5 GLN A 103
VAL A 138
THR A 458
TYR A 146
LEU A 292
None
1.13A 5jh7D-1wd3A:
undetectable
5jh7D-1wd3A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wer P120GAP

(Homo sapiens)
PF00616
(RasGAP)
5 SER A 817
ASP A 816
GLU A 854
PRO A 912
LEU A 930
None
1.36A 5jh7D-1werA:
undetectable
5jh7D-1werA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xip NUCLEOPORIN NUP159

(Saccharomyces
cerevisiae)
PF16755
(NUP214)
5 ASN A  46
VAL A 339
ASP A  43
TYR A 279
PRO A 336
None
1.37A 5jh7D-1xipA:
undetectable
5jh7D-1xipA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq9 PERIPLASMIC [NIFE]
HYDROGENASE SMALL
SUBUNIT


(Desulfovibrio
gigas)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
5 VAL A  24
SER A  21
THR A  18
GLU A  73
LEU A  35
None
None
None
SF4  A 267 ( 4.9A)
None
1.27A 5jh7D-1yq9A:
3.2
5jh7D-1yq9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yya TRIOSEPHOSPHATE
ISOMERASE


(Thermus
thermophilus)
PF00121
(TIM)
5 VAL A 213
SER A 212
THR A 173
TYR A 209
LEU A 221
None
PO4  A2004 (-4.0A)
None
None
None
1.40A 5jh7D-1yyaA:
undetectable
5jh7D-1yyaA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aif RIBOSOMAL PROTEIN
L7A


(Cryptosporidium
parvum)
PF01248
(Ribosomal_L7Ae)
5 VAL A  59
THR A 110
TYR A  85
PRO A  75
LEU A  61
None
1.43A 5jh7D-2aifA:
undetectable
5jh7D-2aifA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2de0 ALPHA-(1,6)-FUCOSYLT
RANSFERASE


(Homo sapiens)
PF14604
(SH3_9)
5 VAL X 262
SER X 263
THR X 265
TYR X 334
LEU X 335
None
1.28A 5jh7D-2de0X:
2.5
5jh7D-2de0X:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eae ALPHA-FUCOSIDASE

(Bifidobacterium
bifidum)
PF14498
(Glyco_hyd_65N_2)
5 GLN A 764
ASN A 395
VAL A 402
SER A 401
TYR A  38
FUC  A 899 (-4.3A)
None
None
None
None
1.37A 5jh7D-2eaeA:
undetectable
5jh7D-2eaeA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eb0 MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE


(Methanocaldococcus
jannaschii)
PF01368
(DHH)
PF02833
(DHHA2)
5 ASN A  36
VAL A 149
SER A 146
THR A  12
GLU A  38
None
1.46A 5jh7D-2eb0A:
undetectable
5jh7D-2eb0A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exr CYTOKININ
DEHYDROGENASE 7


(Arabidopsis
thaliana)
PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind)
5 GLN A  37
ASN A 118
VAL A  66
THR A 115
LEU A  34
None
1.43A 5jh7D-2exrA:
undetectable
5jh7D-2exrA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fn9 RIBOSE ABC
TRANSPORTER,
PERIPLASMIC
RIBOSE-BINDING
PROTEIN


(Thermotoga
maritima)
PF13407
(Peripla_BP_4)
5 SER A  71
ASP A  67
THR A  66
GLU A  46
LEU A  97
None
1.26A 5jh7D-2fn9A:
3.9
5jh7D-2fn9A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv9 DNA POLYMERASE

(Human
alphaherpesvirus
1)
PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
5 ASN A 730
VAL A 258
SER A 734
THR A 735
LEU A 636
None
1.26A 5jh7D-2gv9A:
undetectable
5jh7D-2gv9A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2t LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(LYMPHOCYTE IGE
RECEPTOR)
(FC-EPSILON-RII)
(IMMUNOGLOBULIN
E-BINDING FACTOR)
(CD23 ANTIGEN)


(Homo sapiens)
PF00059
(Lectin_C)
5 GLN B 171
VAL B 199
SER B 200
ASP B 236
TYR B 175
None
1.45A 5jh7D-2h2tB:
undetectable
5jh7D-2h2tB:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ndh TOLL/INTERLEUKIN-1
RECEPTOR
DOMAIN-CONTAINING
ADAPTER PROTEIN


(Homo sapiens)
PF13676
(TIR_2)
5 VAL A 197
TYR A 195
PRO A 177
TYR A 187
LEU A 191
None
1.34A 5jh7D-2ndhA:
undetectable
5jh7D-2ndhA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohc TRNA-SPLICING
ENDONUCLEASE


(Thermoplasma
acidophilum)
PF01974
(tRNA_int_endo)
5 VAL A 241
SER A 242
TYR A 239
PRO A 145
LEU A 209
None
1.27A 5jh7D-2ohcA:
undetectable
5jh7D-2ohcA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi5 DNA-DIRECTED RNA
POLYMERASE


(Escherichia
virus T7)
PF00940
(RNA_pol)
PF14700
(RPOL_N)
5 GLN A  36
VAL A 429
SER A 430
TYR A 286
LEU A 294
None
1.28A 5jh7D-2pi5A:
undetectable
5jh7D-2pi5A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfq 3-HSA HYDROXYLASE,
OXYGENASE


(Rhodococcus
jostii)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2)
5 VAL A 104
ASP A 108
THR A 109
PRO A 169
LEU A 167
None
1.37A 5jh7D-2rfqA:
undetectable
5jh7D-2rfqA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4n MULTIFUNCTIONAL
PROTEIN SUR E


(Salmonella
enterica)
PF01975
(SurE)
5 ASN A  96
VAL A  88
SER A  89
THR A 106
LEU A 142
PO4  A1257 (-3.2A)
None
None
None
None
1.31A 5jh7D-2v4nA:
2.6
5jh7D-2v4nA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w92 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D


(Streptococcus
pneumoniae)
PF03644
(Glyco_hydro_85)
5 ASN A 590
VAL A 561
ASP A 253
THR A 535
TYR A 609
None
1.30A 5jh7D-2w92A:
2.8
5jh7D-2w92A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yok EXOGLUCANASE 1

(Trichoderma
harzianum)
PF00840
(Glyco_hydro_7)
5 GLN A 199
ASP A 163
TYR A 184
PRO A 190
LEU A 193
None
1.21A 5jh7D-2yokA:
undetectable
5jh7D-2yokA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a71 EXO-ARABINANASE

(Penicillium
chrysogenum)
no annotation 5 VAL A 371
SER A 370
GLU A 333
PRO A  26
LEU A 344
None
1.44A 5jh7D-3a71A:
undetectable
5jh7D-3a71A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bin BAND 4.1-LIKE
PROTEIN 3


(Homo sapiens)
PF00373
(FERM_M)
PF09379
(FERM_N)
PF09380
(FERM_C)
5 VAL A 186
THR A 154
TYR A 150
PRO A 190
LEU A 205
None
1.47A 5jh7D-3binA:
undetectable
5jh7D-3binA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d31 SULFATE/MOLYBDATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN


(Methanosarcina
acetivorans)
PF00005
(ABC_tran)
PF03459
(TOBE)
5 GLN A 134
SER A 156
ASP A 187
THR A 185
GLU A 153
None
1.41A 5jh7D-3d31A:
undetectable
5jh7D-3d31A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dev SH1221

(Staphylococcus
haemolyticus)
PF01368
(DHH)
PF02272
(DHHA1)
5 GLN A 112
VAL A  81
ASP A  83
TYR A 113
LEU A 101
None
None
MG  A 323 (-2.7A)
None
None
1.45A 5jh7D-3devA:
undetectable
5jh7D-3devA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dul O-METHYLTRANSFERASE,
PUTATIVE


(Bacillus cereus)
PF01596
(Methyltransf_3)
5 VAL A  42
SER A  43
ASP A 214
THR A 207
TYR A  71
None
1.34A 5jh7D-3dulA:
undetectable
5jh7D-3dulA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dul O-METHYLTRANSFERASE,
PUTATIVE


(Bacillus cereus)
PF01596
(Methyltransf_3)
5 VAL A  42
SER A  43
THR A 207
TYR A  71
LEU A  29
None
1.22A 5jh7D-3dulA:
undetectable
5jh7D-3dulA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2d ALKALINE PHOSPHATASE

(Vibrio sp.
G15-21)
PF00245
(Alk_phosphatase)
5 VAL A 109
SER A 110
ASP A 111
THR A 112
LEU A 265
None
None
None
MG  A 603 ( 4.8A)
None
1.14A 5jh7D-3e2dA:
2.1
5jh7D-3e2dA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE


(Arabidopsis
thaliana)
PF00155
(Aminotran_1_2)
5 SER A 238
ASP A 237
GLU A 264
PRO A 363
TYR A 271
GOL  A 436 (-3.4A)
PLP  A 433 (-3.1A)
GOL  A 436 (-3.3A)
None
GOL  A 436 (-4.6A)
1.36A 5jh7D-3ei8A:
undetectable
5jh7D-3ei8A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcx S-FORMYLGLUTATHIONE
HYDROLASE


(Homo sapiens)
PF00756
(Esterase)
5 ASN A 162
VAL A 107
THR A 125
TYR A 191
LEU A 192
None
1.44A 5jh7D-3fcxA:
2.8
5jh7D-3fcxA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdb PUTATIVE
UNCHARACTERIZED
PROTEIN SPR0440


(Streptococcus
pneumoniae)
PF03644
(Glyco_hydro_85)
5 ASN A 590
VAL A 561
ASP A 253
THR A 535
TYR A 609
None
1.31A 5jh7D-3gdbA:
2.3
5jh7D-3gdbA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gr5 ESCC

(Escherichia
coli)
no annotation 5 VAL A  63
SER A  62
GLU A 105
TYR A  87
LEU A  46
None
1.29A 5jh7D-3gr5A:
undetectable
5jh7D-3gr5A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8l NADH OXIDASE

(Acidianus
ambivalens)
PF07992
(Pyr_redox_2)
5 VAL A  88
THR A 278
TYR A  90
TYR A 102
LEU A   5
None
1.29A 5jh7D-3h8lA:
2.3
5jh7D-3h8lA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8y PHOSPHOPENTOMUTASE

(Bacillus cereus)
PF01676
(Metalloenzyme)
5 VAL A  15
THR A 340
GLU A 342
TYR A 298
LEU A 302
None
0.97A 5jh7D-3m8yA:
undetectable
5jh7D-3m8yA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3md3 NUCLEAR AND
CYTOPLASMIC
POLYADENYLATED
RNA-BINDING PROTEIN
PUB1


(Saccharomyces
cerevisiae)
PF00076
(RRM_1)
5 GLN A 155
VAL A 208
SER A 209
THR A 161
LEU A 178
GOL  A 244 ( 3.7A)
None
None
None
None
1.36A 5jh7D-3md3A:
undetectable
5jh7D-3md3A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster)
PF00291
(PALP)
PF00571
(CBS)
5 VAL A 424
SER A 423
ASP A 418
PRO A 415
LEU A 479
None
1.37A 5jh7D-3pc3A:
2.9
5jh7D-3pc3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r2t PUTATIVE
UNCHARACTERIZED
PROTEIN


(Staphylococcus
aureus)
PF02876
(Stap_Strp_tox_C)
PF09199
(SSL_OB)
5 VAL A 122
ASP A 102
GLU A 162
TYR A  94
LEU A  86
None
1.15A 5jh7D-3r2tA:
undetectable
5jh7D-3r2tA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqo CYSTEINYL-TRNA
SYNTHETASE


(Coxiella
burnetii)
PF01406
(tRNA-synt_1e)
PF09190
(DALR_2)
5 ASN A  -1
VAL A   3
SER A   2
TYR A  60
LEU A  55
None
1.17A 5jh7D-3tqoA:
undetectable
5jh7D-3tqoA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v3k PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815


(Escherichia
coli)
PF16809
(NleF_casp_inhib)
5 GLN B  67
VAL B  73
SER B  74
ASP B  78
PRO B 144
None
1.42A 5jh7D-3v3kB:
undetectable
5jh7D-3v3kB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vm7 ALPHA-AMYLASE

(Malbranchea
cinnamomea)
PF00128
(Alpha-amylase)
PF09260
(DUF1966)
5 ASN A 394
VAL A 449
ASP A 482
TYR A 443
LEU A 466
None
1.25A 5jh7D-3vm7A:
undetectable
5jh7D-3vm7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbh ALKALINE PHOSPHATASE

(Halomonas sp.
#593)
PF00245
(Alk_phosphatase)
5 VAL A 109
SER A 110
ASP A 111
THR A 112
LEU A 261
None
None
None
MG  A 501 ( 4.8A)
None
1.16A 5jh7D-3wbhA:
2.2
5jh7D-3wbhA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btp P1

(Pseudomonas
phage phi8)
no annotation 5 SER A 509
ASP A 501
TYR A 515
PRO A 566
LEU A 567
None
1.41A 5jh7D-4btpA:
undetectable
5jh7D-4btpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btp P1

(Pseudomonas
phage phi8)
no annotation 5 VAL A 510
SER A 509
ASP A 501
TYR A 515
LEU A 567
None
1.21A 5jh7D-4btpA:
undetectable
5jh7D-4btpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c4o CARBONYL REDUCTASE
CPCR2


(Candida
parapsilosis)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
5 ASN A 290
VAL A  87
SER A 138
TYR A  81
LEU A  34
None
1.19A 5jh7D-4c4oA:
undetectable
5jh7D-4c4oA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis)
PF00141
(peroxidase)
5 ASN A 493
VAL A 538
SER A 539
THR A 572
LEU A 458
None
1.23A 5jh7D-4c51A:
undetectable
5jh7D-4c51A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr4 26S PROTEASE
REGULATORY SUBUNIT 8
HOMOLOG


(Saccharomyces
cerevisiae)
PF00004
(AAA)
5 GLN J 220
VAL J 213
SER J 214
GLU J 249
LEU J 233
None
1.22A 5jh7D-4cr4J:
undetectable
5jh7D-4cr4J:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4miv N-SULPHOGLUCOSAMINE
SULPHOHYDROLASE


(Homo sapiens)
PF00884
(Sulfatase)
PF16347
(DUF4976)
5 GLN A 239
SER A 272
ASP A 273
GLU A 292
LEU A  50
None
None
CA  A 601 (-2.3A)
None
None
1.44A 5jh7D-4mivA:
undetectable
5jh7D-4mivA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnr PEPTIDOGLYCAN
GLYCOSYLTRANSFERASE


(Eggerthella
lenta)
PF00905
(Transpeptidase)
5 VAL A 106
ASP A 341
THR A 109
TYR A  76
LEU A  80
None
1.41A 5jh7D-4mnrA:
undetectable
5jh7D-4mnrA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4muo UNCHARACTERIZED
PROTEIN YBIB


(Escherichia
coli)
PF02885
(Glycos_trans_3N)
5 ASN A  96
SER A  87
THR A  98
GLU A 231
LEU A 169
None
1.27A 5jh7D-4muoA:
undetectable
5jh7D-4muoA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7t PHOSPHOPENTOMUTASE

(Streptococcus
mutans)
PF01676
(Metalloenzyme)
5 VAL A  15
THR A 352
GLU A 354
TYR A 310
LEU A 314
None
1.00A 5jh7D-4n7tA:
undetectable
5jh7D-4n7tA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9f CULLIN-5

(Homo sapiens)
no annotation 5 GLN U  63
VAL U 135
ASP U 141
THR U 142
LEU U 114
None
1.35A 5jh7D-4n9fU:
undetectable
5jh7D-4n9fU:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4np6 ADENYLATE KINASE

(Vibrio cholerae)
PF00406
(ADK)
PF05191
(ADK_lid)
5 VAL A 106
ASP A 104
TYR A 182
PRO A  87
LEU A   6
None
1.16A 5jh7D-4np6A:
3.0
5jh7D-4np6A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy2 TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 1
TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 7


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF12157
(DUF3591)
PF04658
(TAFII55_N)
5 GLN A 489
VAL B 170
SER B 189
PRO A 554
LEU A 557
None
1.38A 5jh7D-4oy2A:
undetectable
5jh7D-4oy2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6y AMINOPEPTIDASE

(Thermotoga
maritima)
PF05343
(Peptidase_M42)
5 VAL A 299
SER A 300
ASP A 220
THR A 222
LEU A 261
None
1.26A 5jh7D-4p6yA:
3.1
5jh7D-4p6yA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v20 CELLOBIOHYDROLASE

(Aspergillus
fumigatus)
PF00840
(Glyco_hydro_7)
5 GLN A 186
ASP A 150
TYR A 171
PRO A 177
LEU A 180
None
1.21A 5jh7D-4v20A:
undetectable
5jh7D-4v20A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x27 FUSOLIN

(Entomopoxvirinae)
PF03067
(LPMO_10)
5 GLN A 208
ASN A 159
VAL A 113
SER A 114
THR A 162
None
1.44A 5jh7D-4x27A:
undetectable
5jh7D-4x27A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeb GLUCANASE

(Talaromyces
funiculosus)
PF00840
(Glyco_hydro_7)
5 GLN A 183
ASP A 147
TYR A 168
PRO A 174
LEU A 177
None
1.29A 5jh7D-4xebA:
undetectable
5jh7D-4xebA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
5 GLN A 724
ASN A 760
THR A 764
TYR A 735
LEU A 717
None
1.45A 5jh7D-4xmvA:
undetectable
5jh7D-4xmvA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ykn PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT
ALPHA,PHOSPHATIDYLIN
OSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM FUSION
PROTEIN


(Homo sapiens)
PF00017
(SH2)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B)
PF16454
(PI3K_P85_iSH2)
5 GLN A1637
ASN A1677
THR A1679
PRO A1607
TYR A1641
None
1.45A 5jh7D-4yknA:
undetectable
5jh7D-4yknA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5apg TSR3

(Vulcanisaeta
distributa)
PF04034
(Ribo_biogen_C)
5 ASN A  18
VAL A 116
THR A  19
PRO A   3
LEU A  66
EEM  A1185 (-3.8A)
None
EEM  A1185 (-2.7A)
None
None
1.46A 5jh7D-5apgA:
undetectable
5jh7D-5apgA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4r KETOL-ACID
REDUCTOISOMERASE


(Ignisphaera
aggregans)
PF01450
(IlvC)
PF07991
(IlvN)
5 VAL A 398
SER A 399
ASP A 400
THR A 401
PRO A 135
40E  A 504 ( 3.7A)
40E  A 504 ( 2.5A)
NAP  A 501 ( 4.4A)
None
None
1.44A 5jh7D-5e4rA:
undetectable
5jh7D-5e4rA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyw TRIOSEPHOSPHATE
ISOMERASE


(Litopenaeus
vannamei)
PF00121
(TIM)
5 VAL A 213
SER A 212
THR A 173
TYR A 209
LEU A 221
None
PGA  A 301 (-3.6A)
None
None
None
1.37A 5jh7D-5eywA:
undetectable
5jh7D-5eywA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flw EXO-BETA-1,3-GALACTA
NASE


(Bifidobacterium
bifidum)
PF04616
(Glyco_hydro_43)
5 SER A 295
ASP A 296
THR A 297
PRO A 235
LEU A 292
None
1.42A 5jh7D-5flwA:
undetectable
5jh7D-5flwA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fur TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 2


(Homo sapiens)
no annotation 5 ASN I 246
VAL I 498
SER I 360
THR I 242
LEU I 476
None
1.45A 5jh7D-5furI:
undetectable
5jh7D-5furI:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT


(Escherichia
coli)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2)
5 ASN C 210
VAL C 268
SER C 195
THR C 208
LEU C 114
None
1.28A 5jh7D-5g5gC:
undetectable
5jh7D-5g5gC:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzp TRIOSEPHOSPHATE
ISOMERASE


(Plasmodium
falciparum)
PF00121
(TIM)
5 VAL A 212
SER A 211
THR A 172
TYR A 208
LEU A 220
None
PGA  A 301 (-3.6A)
None
None
None
1.34A 5jh7D-5gzpA:
undetectable
5jh7D-5gzpA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h3k SLR0280 PROTEIN

(Synechocystis
sp. PCC 6803)
no annotation 5 GLN A 409
SER A 427
ASP A 428
GLU A 430
LEU A 349
None
1.37A 5jh7D-5h3kA:
undetectable
5jh7D-5h3kA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hph HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL


(Homo sapiens)
PF00183
(HSP90)
PF13589
(HATPase_c_3)
5 SER A 221
THR A 164
GLU A 167
PRO A 139
LEU A 131
None
1.27A 5jh7D-5hphA:
undetectable
5jh7D-5hphA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kel EBOLA SURFACE
GLYCOPROTEIN, GP1


(Zaire
ebolavirus)
PF01611
(Filo_glycop)
5 GLN A 251
ASN A 107
ASP A  78
THR A  77
LEU A 256
None
1.39A 5jh7D-5kelA:
undetectable
5jh7D-5kelA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ken EBOLA SURFACE
GLYCOPROTEIN, GP1


(Zaire
ebolavirus)
PF01611
(Filo_glycop)
5 GLN A 251
ASN A 107
ASP A  78
THR A  77
LEU A 256
None
1.39A 5jh7D-5kenA:
undetectable
5jh7D-5kenA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l75 LIPOPOLYSACCHARIDE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
LPTB


(Klebsiella
pneumoniae)
PF00005
(ABC_tran)
PF12399
(BCA_ABC_TP_C)
5 VAL A 197
ASP A 194
THR A 193
TYR A 234
LEU A 235
None
1.23A 5jh7D-5l75A:
undetectable
5jh7D-5l75A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liq NICKING ENDONUCLEASE
N.BSPD6I


(Bacillus sp.
(in: Bacteria))
PF09491
(RE_AlwI)
5 VAL A   9
SER A  10
PRO A 137
TYR A  79
LEU A 113
None
1.33A 5jh7D-5liqA:
undetectable
5jh7D-5liqA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ljo OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA


(Escherichia
coli)
PF01103
(Bac_surface_Ag)
PF07244
(POTRA)
5 GLN A 179
VAL A 245
SER A 246
THR A 248
LEU A 219
None
1.38A 5jh7D-5ljoA:
undetectable
5jh7D-5ljoA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE


(Bacteroides
thetaiotaomicron)
PF07944
(Glyco_hydro_127)
5 GLN A 468
ASN A 461
VAL A 408
TYR A 472
LEU A 485
None
1.28A 5jh7D-5mqoA:
undetectable
5jh7D-5mqoA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5nd4 TUBULIN ALPHA CHAIN

(Bos taurus)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
5 GLN A  11
ASN A 101
PRO A 222
TYR A 224
LEU A 227
GTP  A 500 ( 3.1A)
GTP  A 500 (-3.3A)
None
GTP  A 500 (-3.2A)
GTP  A 500 ( 4.1A)
0.97A 5jh7D-5nd4A:
51.7
5jh7D-5nd4A:
38.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5nd4 TUBULIN ALPHA CHAIN

(Bos taurus)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
5 GLN A  11
GLU A 183
PRO A 222
TYR A 224
LEU A 227
GTP  A 500 ( 3.1A)
GTP  A 500 (-3.3A)
None
GTP  A 500 (-3.2A)
GTP  A 500 ( 4.1A)
0.74A 5jh7D-5nd4A:
51.7
5jh7D-5nd4A:
38.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nh0 REPLICASE
POLYPROTEIN 1AB


(Human
coronavirus
NL63)
no annotation 5 GLN A 267
ASN A 231
VAL A 204
SER A 201
ASP A 202
None
None
None
None
DMS  A 302 (-3.8A)
1.47A 5jh7D-5nh0A:
undetectable
5jh7D-5nh0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o5d GLUCANASE

(Trichoderma
atroviride)
no annotation 5 GLN A 186
ASP A 150
TYR A 171
PRO A 177
LEU A 180
None
1.16A 5jh7D-5o5dA:
undetectable
5jh7D-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5of4 TFIIH BASAL
TRANSCRIPTION FACTOR
COMPLEX HELICASE XPD
SUBUNIT


(Homo sapiens)
PF06733
(DEAD_2)
PF06777
(HBB)
PF13307
(Helicase_C_2)
5 VAL B  83
THR B  76
GLU B  79
TYR B  72
LEU B  53
None
1.42A 5jh7D-5of4B:
undetectable
5jh7D-5of4B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyp STRUCTURAL PROTEIN
VP2


(Sacbrood virus)
no annotation 5 ASN B  21
TYR B 110
PRO B  85
TYR B 222
LEU B 112
None
1.13A 5jh7D-5oypB:
undetectable
5jh7D-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9z PHOSPHOGLYCEROL
TRANSFERASE


(Streptococcus
pyogenes)
no annotation 5 SER A 491
ASP A 733
THR A 732
TYR A 679
LEU A 676
None
1.26A 5jh7D-5u9zA:
undetectable
5jh7D-5u9zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5upr TRIOSEPHOSPHATE
ISOMERASE


(Toxoplasma
gondii)
PF00121
(TIM)
5 VAL A 336
SER A 335
THR A 296
TYR A 332
LEU A 344
None
SO4  A 401 (-3.7A)
None
None
None
1.45A 5jh7D-5uprA:
undetectable
5jh7D-5uprA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uto EDD DOMAIN PROTEIN,
DEGV FAMILY


(Staphylococcus
aureus)
no annotation 5 VAL A 222
ASP A 224
TYR A 280
TYR A 256
LEU A 230
None
1.48A 5jh7D-5utoA:
2.5
5jh7D-5utoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8z ENDOPLASMIC
RETICULUM RESIDENT
PROTEIN 29


(Homo sapiens)
PF07749
(ERp29)
5 GLN A 183
VAL A 191
SER A 190
TYR A 161
LEU A 158
None
1.38A 5jh7D-5v8zA:
undetectable
5jh7D-5v8zA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5y PROBABLE ATP-BINDING
COMPONENT OF ABC
TRANSPORTER


(Pseudomonas
aeruginosa)
no annotation 5 VAL B 197
ASP B 194
THR B 193
TYR B 234
LEU B 235
None
1.10A 5jh7D-5x5yB:
undetectable
5jh7D-5x5yB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze8 CYTOCHROME C552

(Thermochromatium
tepidum)
no annotation 5 VAL A  40
SER A  41
GLU A 123
PRO A 208
LEU A 210
None
None
None
None
HEM  A 501 (-4.6A)
1.22A 5jh7D-5ze8A:
undetectable
5jh7D-5ze8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cnk IGG1 KAPPA LIGHT
CHAIN
IGG1 HEAVY CHAIN


(Mus musculus;
Mus musculus)
no annotation
no annotation
5 ASN G  60
VAL G  38
TYR G  96
PRO F  49
LEU G  46
None
1.31A 5jh7D-6cnkG:
undetectable
5jh7D-6cnkG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cpy GRMZM2G135359
PSEUDOKINASE


(Zea mays)
no annotation 5 VAL A 362
SER A 359
ASP A 358
GLU A 411
LEU A 364
None
1.42A 5jh7D-6cpyA:
undetectable
5jh7D-6cpyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d04 RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE


(Plasmodium
vivax)
no annotation 5 ASN E 428
VAL E 395
SER E 398
TYR E 337
LEU E 440
None
1.24A 5jh7D-6d04E:
undetectable
5jh7D-6d04E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ek2 SINGLE CHAIN FV
FRAGMENT


(Mus musculus)
no annotation 5 VAL H 206
THR H 219
TYR H 264
PRO H 382
LEU H 214
None
1.38A 5jh7D-6ek2H:
undetectable
5jh7D-6ek2H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN


(Burkholderia
pseudomallei)
no annotation 5 VAL A 230
ASP A 227
THR A 226
TYR A 267
LEU A 268
None
1.15A 5jh7D-6flxA:
undetectable
5jh7D-6flxA:
undetectable