SIMILAR PATTERNS OF AMINO ACIDS FOR 5JH7_B_6K9B503_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1air PECTATE LYASE C

(Dickeya
chrysanthemi) 		PF00544
(Pec_lyase_C) 		4 VAL A 135
ASN A 210
ILE A 185
VAL A 169
 None
 1.19A 5jh7C-1airA:
undetectable		 5jh7C-1airA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bsl BACTERIAL LUCIFERASE

(Vibrio harveyi) 		PF00296
(Bac_luciferase) 		4 GLU A  89
ASN A   9
ILE A  21
VAL A  58
 None
 0.96A 5jh7C-1bslA:
undetectable		 5jh7C-1bslA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h5q NADP-DEPENDENT
MANNITOL
DEHYDROGENASE

(Agaricus
bisporus) 		PF13561
(adh_short_C2) 		4 VAL A  55
GLU A  58
ASN A  96
ILE A  94
 None
None
NAP  A 263 (-3.5A)
None
 0.94A 5jh7C-1h5qA:
6.6		 5jh7C-1h5qA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hww ALPHA-MANNOSIDASE II

(Drosophila
melanogaster) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 LEU A 494
VAL A 436
GLU A 440
ILE A 474
 None
 1.20A 5jh7C-1hwwA:
undetectable		 5jh7C-1hwwA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itu RENAL DIPEPTIDASE

(Homo sapiens) 		PF01244
(Peptidase_M19) 		4 LEU A 196
VAL A 201
ILE A 274
VAL A 232
 None
 1.11A 5jh7C-1ituA:
undetectable		 5jh7C-1ituA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2z ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Helicobacter
pylori) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		4 LEU A  64
GLU A  79
ILE A  16
VAL A  32
 None
 0.92A 5jh7C-1j2zA:
undetectable		 5jh7C-1j2zA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksi COPPER AMINE OXIDASE

(Pisum sativum) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 LEU A 622
GLU A 505
ILE A 593
VAL A 508
 None
 1.16A 5jh7C-1ksiA:
undetectable		 5jh7C-1ksiA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqq ALPHA-D-GLUCURONIDAS
E

(Geobacillus
stearothermophilus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		4 LEU A 314
VAL A 279
ASN A 193
ILE A 230
 None
 0.81A 5jh7C-1mqqA:
undetectable		 5jh7C-1mqqA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvm ACETALDEHYDE
DEHYDROGENASE
(ACYLATING)

(Pseudomonas sp.
CF600) 		PF01118
(Semialdhyde_dh)
PF09290
(AcetDehyd-dimer) 		4 VAL B  60
GLU B  61
ASN B 126
ILE B 108
 None
MPD  B3528 (-3.4A)
None
None
 1.03A 5jh7C-1nvmB:
2.9		 5jh7C-1nvmB:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4u TYPE II QUINOLIC
ACID
PHOSPHORIBOSYLTRANSF
ERASE

(Thermotoga
maritima) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 LEU A  94
GLU A  55
ILE A 136
VAL A  49
 None
 1.15A 5jh7C-1o4uA:
undetectable		 5jh7C-1o4uA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pg6 HYPOTHETICAL PROTEIN
SPYM3_0169

(Streptococcus
pyogenes) 		PF01987
(AIM24) 		4 LEU A 108
VAL A 142
GLU A 125
ILE A 171
 None
 1.13A 5jh7C-1pg6A:
undetectable		 5jh7C-1pg6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rie RIESKE IRON-SULFUR
PROTEIN

(Bos taurus) 		PF00355
(Rieske) 		4 LEU A 180
VAL A 182
ASN A  86
VAL A 133
 None
 1.11A 5jh7C-1rieA:
undetectable		 5jh7C-1rieA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rqg METHIONYL-TRNA
SYNTHETASE

(Pyrococcus
abyssi) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 LEU A 199
ILE A 300
LYS A 213
VAL A 216
 None
 1.03A 5jh7C-1rqgA:
undetectable		 5jh7C-1rqgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlk TELOKIN

(Meleagris
gallopavo) 		PF07679
(I-set) 		4 VAL A 118
GLU A 123
ILE A  90
VAL A  73
 None
 1.19A 5jh7C-1tlkA:
undetectable		 5jh7C-1tlkA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uar RHODANESE

(Thermus
thermophilus) 		PF00581
(Rhodanese) 		4 LEU A 110
VAL A   8
GLU A   7
VAL A 108
 None
 1.15A 5jh7C-1uarA:
undetectable		 5jh7C-1uarA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vl8 GLUCONATE
5-DEHYDROGENASE

(Thermotoga
maritima) 		PF13561
(adh_short_C2) 		4 LEU A  77
GLU A  72
ASN A  93
VAL A  68
 None
None
None
NAP  A 274 (-3.6A)
 1.04A 5jh7C-1vl8A:
6.5		 5jh7C-1vl8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wue MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A1075
VAL A1087
GLU A1105
ILE A1366
 None
 1.13A 5jh7C-1wueA:
3.2		 5jh7C-1wueA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkt FATTY ACID SYNTHASE

(Homo sapiens) 		PF00975
(Thioesterase) 		4 LEU A2416
VAL A2397
GLU A2394
ILE A2250
 None
 1.12A 5jh7C-1xktA:
3.8		 5jh7C-1xktA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B

(Bacillus cereus) 		PF00994
(MoCF_biosynth) 		4 LEU A  77
VAL A  19
GLU A  51
ILE A  91
 None
 0.98A 5jh7C-1y5eA:
undetectable		 5jh7C-1y5eA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Thermotoga
maritima) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 VAL A 170
GLU A 173
ASN A 284
ILE A 286
 None
 1.17A 5jh7C-1z82A:
undetectable		 5jh7C-1z82A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c8j FERROCHELATASE 1

(Bacillus
anthracis) 		PF00762
(Ferrochelatase) 		4 VAL A  77
GLU A  76
ILE A 143
LYS A 307
 None
 1.15A 5jh7C-2c8jA:
3.5		 5jh7C-2c8jA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 LEU A 294
GLU A 306
ILE A 364
VAL A 291
 None
None
UQ5  A 612 ( 4.8A)
UQ5  A 612 ( 4.9A)
 1.21A 5jh7C-2gmhA:
undetectable		 5jh7C-2gmhA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		4 LEU A 370
VAL A 419
ILE A 350
VAL A  39
 None
 1.19A 5jh7C-2gq3A:
undetectable		 5jh7C-2gq3A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6l MITOGEN-ACTIVATED
PROTEIN KINASE 6

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A  72
VAL A  78
ILE A  83
VAL A  80
 None
 1.07A 5jh7C-2i6lA:
undetectable		 5jh7C-2i6lA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jfe CYTOSOLIC
BETA-GLUCOSIDASE

(Homo sapiens) 		PF00232
(Glyco_hydro_1) 		4 GLU X 230
ASN X 374
ILE X 371
VAL X 353
 None
 1.16A 5jh7C-2jfeX:
2.6		 5jh7C-2jfeX:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lv5 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF10052
(DUF2288) 		4 LEU A  37
VAL A  48
GLU A  47
VAL A  60
 None
 1.20A 5jh7C-2lv5A:
undetectable		 5jh7C-2lv5A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m9v TELOMERE REPLICATION
PROTEIN EST3

(Saccharomyces
cerevisiae) 		PF10341
(TPP1) 		4 LEU A  45
GLU A  98
ILE A  84
VAL A 157
 None
 1.15A 5jh7C-2m9vA:
undetectable		 5jh7C-2m9vA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbg RALA-BINDING PROTEIN
1

(Homo sapiens) 		PF00620
(RhoGAP) 		4 LEU A 373
GLU A 215
ILE A 230
VAL A 220
 None
 0.92A 5jh7C-2mbgA:
undetectable		 5jh7C-2mbgA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 LEU A 853
GLU A 868
ASN A 722
ILE A 725
 None
 1.13A 5jh7C-2nz9A:
undetectable		 5jh7C-2nz9A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pw6 UNCHARACTERIZED
PROTEIN YGID

(Escherichia
coli) 		PF02900
(LigB) 		4 LEU A 238
GLU A 233
ASN A 198
ILE A 258
 None
ZN  A 274 ( 4.6A)
None
None
 1.10A 5jh7C-2pw6A:
undetectable		 5jh7C-2pw6A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va1 URIDYLATE KINASE

(Ureaplasma
parvum) 		PF00696
(AA_kinase) 		4 LEU A  31
GLU A  85
ASN A  52
ILE A  22
 None
 0.96A 5jh7C-2va1A:
undetectable		 5jh7C-2va1A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 LEU A1061
GLU A1088
ASN A1017
ILE A 984
 None
 1.17A 5jh7C-2vdcA:
2.3		 5jh7C-2vdcA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w2d BOTULINUM NEUROTOXIN
A HEAVY CHAIN

(Clostridium
botulinum) 		PF07952
(Toxin_trans) 		4 LEU B 853
GLU B 868
ASN B 722
ILE B 725
 None
 1.20A 5jh7C-2w2dB:
undetectable		 5jh7C-2w2dB:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3p BENZOYL-COA-DIHYDROD
IOL LYASE

(Paraburkholderia
xenovorans) 		PF00378
(ECH_1) 		4 LEU A 318
GLU A 324
ILE A  44
VAL A  11
 None
 1.10A 5jh7C-2w3pA:
undetectable		 5jh7C-2w3pA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ygk NURA

(Sulfolobus
solfataricus) 		PF09376
(NurA) 		4 LEU A 131
VAL A  79
GLU A  77
ILE A 295
 None
 1.19A 5jh7C-2ygkA:
undetectable		 5jh7C-2ygkA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
1, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 LEU B 428
GLU B 472
ASN B 455
ILE B 457
 None
 1.03A 5jh7C-2z7xB:
undetectable		 5jh7C-2z7xB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh4 SODIUM/GLUCOSE
COTRANSPORTER

(Vibrio
parahaemolyticus) 		PF00474
(SSF) 		4 VAL A 302
ASN A  64
ILE A  61
VAL A 297
 None
GAL  A 701 (-3.9A)
None
None
 1.00A 5jh7C-3dh4A:
undetectable		 5jh7C-3dh4A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdb PUTATIVE
UNCHARACTERIZED
PROTEIN SPR0440

(Streptococcus
pneumoniae) 		PF03644
(Glyco_hydro_85) 		4 LEU A 562
GLU A 579
ILE A 476
LYS A 488
 None
 1.14A 5jh7C-3gdbA:
2.1		 5jh7C-3gdbA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hka URONATE ISOMERASE

(Bacillus
halodurans) 		no annotation 4 VAL A  22
ASN A 329
ILE A 334
LYS A 370
 None
 0.95A 5jh7C-3hkaA:
undetectable		 5jh7C-3hkaA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1c CHAPERONIN ALPHA
SUBUNIT

(Acidianus
tengchongensis) 		PF00118
(Cpn60_TCP1) 		4 LEU A 283
ILE A 317
LYS A 289
VAL A 287
 None
 1.14A 5jh7C-3j1cA:
undetectable		 5jh7C-3j1cA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 VAL X 407
GLU X 404
ILE X 226
LYS X 269
 None
 0.91A 5jh7C-3jb9X:
undetectable		 5jh7C-3jb9X:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ky9 PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF)
PF11971
(CAMSAP_CH) 		4 LEU A 472
VAL A 454
GLU A 500
ILE A 433
 None
 0.86A 5jh7C-3ky9A:
undetectable		 5jh7C-3ky9A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oml PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2,
CG3415

(Drosophila
melanogaster) 		PF00106
(adh_short)
PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		4 VAL A 196
GLU A 241
ASN A 179
VAL A 194
 None
 1.14A 5jh7C-3omlA:
5.1		 5jh7C-3omlA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pu6 UNCHARACTERIZED
PROTEIN

(Wolinella
succinogenes) 		no annotation 4 LEU A   6
VAL A  35
GLU A  27
ILE A 110
 None
 0.71A 5jh7C-3pu6A:
4.2		 5jh7C-3pu6A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvm OLEI00960

(Oleispira
antarctica) 		PF00561
(Abhydrolase_1) 		4 LEU A  31
VAL A  56
GLU A  51
ILE A 128
 None
 0.81A 5jh7C-3qvmA:
undetectable		 5jh7C-3qvmA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN

(Parabacteroides
distasonis) 		PF06321
(P_gingi_FimA) 		4 LEU A 187
GLU A  63
ILE A 154
VAL A 165
 None
None
EDO  A 325 ( 4.4A)
None
 1.09A 5jh7C-3r4rA:
undetectable		 5jh7C-3r4rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3see HYPOTHETICAL SUGAR
BINDING PROTEIN

(Bacteroides
thetaiotaomicron) 		PF15425
(DUF4627) 		4 LEU A 107
ILE A 164
LYS A 172
VAL A 173
 None
 1.14A 5jh7C-3seeA:
undetectable		 5jh7C-3seeA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE

(Paraburkholderia
xenovorans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 109
VAL A 334
ASN A  91
ILE A 292
 None
 1.16A 5jh7C-3sn0A:
undetectable		 5jh7C-3sn0A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tzq SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE

(Mycobacterium
marinum) 		no annotation 4 VAL B  68
GLU B  65
ASN B 139
ILE B 162
 None
 1.06A 5jh7C-3tzqB:
6.9		 5jh7C-3tzqB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vjj P9-1

(Rice black
streaked dwarf
virus) 		PF06043
(Reo_P9) 		4 LEU A 191
VAL A 176
GLU A 187
VAL A 172
 None
 1.20A 5jh7C-3vjjA:
undetectable		 5jh7C-3vjjA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiq KOJIBIOSE
PHOSPHORYLASE

(Caldicellulosiruptor
saccharolyticus) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 LEU A  74
VAL A  41
GLU A  45
ILE A 200
 None
 1.17A 5jh7C-3wiqA:
undetectable		 5jh7C-3wiqA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 LEU B1302
VAL B1304
GLU B1308
ILE B1444
 None
 1.13A 5jh7C-3zefB:
undetectable		 5jh7C-3zefB:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a7w URIDYLATE KINASE

(Helicobacter
pylori) 		PF00696
(AA_kinase) 		4 LEU A 183
ILE A 204
LYS A 240
VAL A 239
 None
 1.05A 5jh7C-4a7wA:
undetectable		 5jh7C-4a7wA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4are COLLAGENASE G

(Hathewaya
histolytica) 		PF01752
(Peptidase_M9)
PF08453
(Peptidase_M9_N) 		4 VAL A 378
GLU A 381
ASN A 287
ILE A 290
 None
None
P6G  A1791 ( 4.3A)
None
 1.19A 5jh7C-4areA:
undetectable		 5jh7C-4areA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dbe OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Sulfolobus
solfataricus) 		PF00215
(OMPdecase) 		4 LEU A   8
GLU A  55
ASN A 204
ILE A 207
 None
 1.19A 5jh7C-4dbeA:
undetectable		 5jh7C-4dbeA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF14725
(DUF4466) 		4 LEU A 266
GLU A 297
ILE A 198
VAL A 326
 None
 1.03A 5jh7C-4ei0A:
undetectable		 5jh7C-4ei0A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl9 TYROSINE-PROTEIN
KINASE

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		4 VAL A 879
GLU A 877
ILE A 899
LYS A 914
 None
 1.19A 5jh7C-4gl9A:
undetectable		 5jh7C-4gl9A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1g MALTOSE BINDING
PROTEIN-CAKAR3 MOTOR
DOMAIN FUSION
PROTEIN

(Escherichia
coli;
Candida
albicans) 		PF00225
(Kinesin)
PF13416
(SBP_bac_8) 		4 GLU A 422
ASN A 626
ILE A 622
VAL A 350
 None
 0.96A 5jh7C-4h1gA:
undetectable		 5jh7C-4h1gA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igd MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		4 LEU A 479
GLU A 557
ILE A 684
VAL A 486
 None
 1.20A 5jh7C-4igdA:
undetectable		 5jh7C-4igdA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkm BETA-GLUCURONIDASE

(Clostridium
perfringens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 LEU A 103
GLU A  31
ILE A 171
VAL A 130
 None
 0.80A 5jh7C-4jkmA:
undetectable		 5jh7C-4jkmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k28 SHIKIMATE
DEHYDROGENASE FAMILY
PROTEIN

(Pseudomonas
putida) 		PF00899
(ThiF)
PF08501
(Shikimate_dh_N) 		4 LEU A 233
GLU A 229
ILE A 140
VAL A 224
 None
None
None
NAD  A 301 (-4.0A)
 1.10A 5jh7C-4k28A:
2.0		 5jh7C-4k28A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9

(Plasmodium
falciparum) 		PF00179
(UQ_con) 		4 LEU A  81
GLU A 132
LYS A 147
VAL A 148
 None
 1.14A 5jh7C-4m1nA:
undetectable		 5jh7C-4m1nA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzd NISIN LEADER
PEPTIDE-PROCESSING
SERINE PROTEASE NISP

(Lactococcus
lactis) 		PF00082
(Peptidase_S8) 		4 LEU A 410
ILE A 428
LYS A 433
VAL A 434
 None
 1.08A 5jh7C-4mzdA:
2.0		 5jh7C-4mzdA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4odj S-ADENOSYLMETHIONINE
SYNTHASE

(Cryptosporidium
hominis) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 LEU A 231
VAL A 234
GLU A 168
ILE A 221
 None
 1.20A 5jh7C-4odjA:
undetectable		 5jh7C-4odjA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psn SSDNA BINDING
PROTEIN

(Aeropyrum
pernix) 		PF10015
(DUF2258) 		4 LEU A 148
VAL A 210
ILE A 119
VAL A 163
 None
 0.70A 5jh7C-4psnA:
undetectable		 5jh7C-4psnA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6x PHOSPHOLIPASE D
STSICTOX-BETAIC1

(Sicarius
terrosus) 		no annotation 4 LEU A 131
VAL A  89
GLU A  31
ILE A 175
 None
None
MG  A 301 (-2.6A)
None
 1.13A 5jh7C-4q6xA:
undetectable		 5jh7C-4q6xA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6g LEUCINE RICH REPEATS
DLRR_K

(synthetic
construct) 		PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 110
GLU A 105
ILE A  58
LYS A  81
 None
 1.08A 5jh7C-4r6gA:
undetectable		 5jh7C-4r6gA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ra6 L-ASPARAGINASE

(Pyrococcus
furiosus) 		PF00710
(Asparaginase) 		4 LEU A 148
GLU A 164
LYS A 145
VAL A 146
 None
 0.80A 5jh7C-4ra6A:
undetectable		 5jh7C-4ra6A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um2 TELOMERASE-BINDING
PROTEIN EST1A

(Homo sapiens) 		PF10373
(EST1_DNA_bind)
PF10374
(EST1) 		4 LEU A 920
VAL A 915
ASN A 946
ILE A 945
 None
 1.07A 5jh7C-4um2A:
undetectable		 5jh7C-4um2A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xfw ALPHA-CARBONIC
ANHYDRASE

(Helicobacter
pylori) 		PF00194
(Carb_anhydrase) 		4 LEU A 142
VAL A 131
ILE A 158
VAL A 109
 None
 0.93A 5jh7C-4xfwA:
undetectable		 5jh7C-4xfwA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztd PROLIFERATING CELL
NUCLEAR ANTIGEN

(Homo sapiens) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A 227
VAL A 136
GLU A 198
ILE A 128
 None
 1.11A 5jh7C-4ztdA:
undetectable		 5jh7C-4ztdA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cx8 LIPOPROTEIN RAGB

(Porphyromonas
gingivalis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 LEU A 408
GLU A 390
ILE A 288
VAL A 384
 None
 1.08A 5jh7C-5cx8A:
undetectable		 5jh7C-5cx8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		4 LEU A  35
GLU A  38
ASN A 995
ILE A 982
 None
 0.83A 5jh7C-5czzA:
undetectable		 5jh7C-5czzA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epo 7-ALPHA-HYDROXYSTERO
ID DEYDROGENASE

(Clostridium
sardiniense) 		PF13561
(adh_short_C2) 		4 VAL A  77
GLU A  81
ASN A  89
ILE A 140
 None
 1.10A 5jh7C-5epoA:
6.1		 5jh7C-5epoA:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5flz TUBULIN GAMMA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 LEU C 412
VAL C 419
GLU C 422
ASN C 153
 None
 1.18A 5jh7C-5flzC:
42.5		 5jh7C-5flzC:
31.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmq INFLUENZA A PB2
SUBUNIT

(Influenza A
virus) 		PF00604
(Flu_PB2) 		4 VAL A 485
GLU A 487
ILE A 398
VAL A 386
 None
 1.17A 5jh7C-5fmqA:
undetectable		 5jh7C-5fmqA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gve DNA TOPOISOMERASE
3-BETA-1

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 VAL A  61
GLU A  91
ILE A 112
VAL A 129
 None
 0.74A 5jh7C-5gveA:
undetectable		 5jh7C-5gveA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1l TOXR-ACTIVATED GENE
(TAGE)

(Helicobacter
pylori) 		PF01551
(Peptidase_M23) 		4 LEU A 174
GLU A 146
ILE A 205
VAL A 182
 None
 1.18A 5jh7C-5j1lA:
undetectable		 5jh7C-5j1lA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jfq GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Geoglobus
acetivorans) 		PF00348
(polyprenyl_synt) 		4 LEU A 120
GLU A 115
ILE A 144
VAL A  73
 None
 1.18A 5jh7C-5jfqA:
undetectable		 5jh7C-5jfqA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mc9 LAMININ SUBUNIT
ALPHA-1

(Mus musculus) 		PF00054
(Laminin_G_1)
PF06009
(Laminin_II) 		4 LEU A2382
ILE A2398
LYS A2372
VAL A2373
 None
 1.18A 5jh7C-5mc9A:
undetectable		 5jh7C-5mc9A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mh5 D-2-HYDROXYACID
DEHYDROGENASE

(Haloferax
mediterranei) 		no annotation 4 LEU A 235
GLU A 204
ILE A 187
VAL A 207
 None
 1.16A 5jh7C-5mh5A:
undetectable		 5jh7C-5mh5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5moy BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 GLU A 982
ASN A1021
ILE A1041
VAL A 997
 None
 1.04A 5jh7C-5moyA:
undetectable		 5jh7C-5moyA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ms7 LEGIONELLA
PNEUMOPHILA EFFECTOR
PROTEIN RAVZ

(Legionella
pneumophila) 		no annotation 4 VAL A  59
GLU A 302
ASN A 248
ILE A 281
 None
 0.93A 5jh7C-5ms7A:
undetectable		 5jh7C-5ms7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6y NITROGENASE
VANADIUM-IRON
PROTEIN BETA CHAIN

(Azotobacter
vinelandii) 		no annotation 4 LEU E 355
VAL E 353
ILE E 454
VAL E 329
 None
 1.18A 5jh7C-5n6yE:
undetectable		 5jh7C-5n6yE:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncr TYROSINE PHOSPHATASE

(Orf virus) 		PF00782
(DSPc) 		4 LEU A  37
VAL A  35
GLU A 102
ILE A  77
 None
 1.10A 5jh7C-5ncrA:
undetectable		 5jh7C-5ncrA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9i TRANSCRIPTION
INITIATION FACTOR
IIB,TRANSCRIPTION
INITIATION FACTOR
IIB

(Methanocaldococcus
vulcanius) 		no annotation 4 VAL A  49
GLU A  12
ILE A 180
VAL A  51
 None
 0.88A 5jh7C-5o9iA:
undetectable		 5jh7C-5o9iA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oas MALATE SYNTHASE G

(Pseudomonas
aeruginosa) 		no annotation 4 LEU A  92
GLU A  96
ILE A 429
LYS A 445
 None
 1.05A 5jh7C-5oasA:
undetectable		 5jh7C-5oasA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ur0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Naegleria
gruberi) 		no annotation 4 LEU A 154
ILE A 255
LYS A 307
VAL A 308
 None
 1.02A 5jh7C-5ur0A:
3.0		 5jh7C-5ur0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wc2 PACHYTENE CHECKPOINT
PROTEIN 2 HOMOLOG

(Homo sapiens) 		no annotation 4 LEU A 296
VAL A 174
ILE A 240
LYS A 288
 None
 1.09A 5jh7C-5wc2A:
undetectable		 5jh7C-5wc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wq7 PUTATIVE TYPE II
SECRETION SYSTEM
PROTEIN D

(Escherichia
coli) 		PF00263
(Secretin)
PF03958
(Secretin_N) 		4 LEU A 109
VAL A 141
GLU A 137
VAL A 107
 None
 1.18A 5jh7C-5wq7A:
undetectable		 5jh7C-5wq7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wsk RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN

(Triticum
aestivum) 		no annotation 4 VAL E 133
GLU E 134
ILE E  81
VAL E 129
 None
 1.09A 5jh7C-5wskE:
undetectable		 5jh7C-5wskE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wt3 TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A

(Pyrococcus
abyssi) 		no annotation 4 LEU A 228
VAL A 155
GLU A 152
ILE A 239
 None
 1.07A 5jh7C-5wt3A:
undetectable		 5jh7C-5wt3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wy0 SMALL RNA
2'-O-METHYLTRANSFERA
SE

(Homo sapiens) 		no annotation 4 LEU A  92
VAL A 119
ILE A  49
VAL A  85
 None
None
SAM  A 800 (-4.0A)
SAM  A 800 (-3.5A)
 1.15A 5jh7C-5wy0A:
undetectable		 5jh7C-5wy0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 LEU A 682
GLU A 729
ASN A 711
ILE A 713
 None
 0.99A 5jh7C-5y3jA:
undetectable		 5jh7C-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 LEU A 683
GLU A 730
ASN A 712
ILE A 714
 None
 1.02A 5jh7C-5zlnA:
undetectable		 5jh7C-5zlnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axe MALATE SYNTHASE G

(Mycobacterium
marinum) 		PF01274
(Malate_synthase) 		4 LEU A 374
VAL A 423
ILE A 350
VAL A  39
 None
 1.17A 5jh7C-6axeA:
undetectable		 5jh7C-6axeA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btg FUCULOSE PHOSPHATE
ALDOLASE

(Bacillus
thuringiensis) 		no annotation 4 LEU A 159
GLU A  76
ILE A 166
VAL A  94
 None
13P  A 302 ( 3.6A)
None
None
 1.15A 5jh7C-6btgA:
undetectable		 5jh7C-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bxa TOLL-LIKE RECEPTOR
5B, VARIABLE
LYMPHOCYTE RECEPTOR
B CHIMERA

(Eptatretus
burgeri;
Danio rerio) 		no annotation 4 LEU A 345
GLU A 392
ASN A 374
ILE A 376
 None
 0.93A 5jh7C-6bxaA:
undetectable		 5jh7C-6bxaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0g PIRIN FAMILY PROTEIN

(Acinetobacter
baumannii) 		no annotation 4 LEU A 157
GLU A 173
ILE A 138
VAL A 171
 None
 1.16A 5jh7C-6d0gA:
undetectable		 5jh7C-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6es9 ACYL-COA
DEHYDROGENASE

(Paracoccus
denitrificans) 		no annotation 4 LEU A 282
VAL A 327
GLU A 350
ILE A 218
 None
 1.16A 5jh7C-6es9A:
undetectable		 5jh7C-6es9A:
undetectable