SIMILAR PATTERNS OF AMINO ACIDS FOR 5JGL_A_SAMA301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxz NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Thermoanaerobacter
brockii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 GLY A  23
ASP A  26
ASN A 132
 None
 0.51A 5jglA-1bxzA:
7.9		 5jglA-1bxzA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA

(Moraxella bovis) 		PF01555
(N6_N4_Mtase) 		3 GLY A 222
ASP A 241
ASN A  11
 SAM  A 500 (-3.2A)
SAM  A 500 (-2.9A)
SAM  A 500 (-4.1A)
 0.35A 5jglA-1g60A:
3.8		 5jglA-1g60A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4p GLUCAN
1,3-BETA-GLUCOSIDASE
I/II

(Saccharomyces
cerevisiae) 		PF00150
(Cellulase) 		3 GLY A 350
ASP A  83
ASN A  79
 None
 0.61A 5jglA-1h4pA:
undetectable		 5jglA-1h4pA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqb NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Clostridium
beijerinckii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 GLY A1023
ASP A1026
ASN A1132
 None
 0.47A 5jglA-1jqbA:
8.4		 5jglA-1jqbA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pl0 BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Homo sapiens) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		3 GLY A 316
ASP A 339
ASN A 361
 None
 0.54A 5jglA-1pl0A:
2.5		 5jglA-1pl0A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8y GLYCINE
N-METHYLTRANSFERASE

(Mus musculus) 		PF13847
(Methyltransf_31) 		3 GLY A  66
ASP A  85
ASN A 116
 None
 0.58A 5jglA-1r8yA:
15.5		 5jglA-1r8yA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sem SEM-5

(Caenorhabditis
elegans) 		PF00018
(SH3_1) 		3 GLY A 178
ASP A 179
ASN A 197
 None
 0.60A 5jglA-1semA:
undetectable		 5jglA-1semA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wg8 PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE

(Thermus
thermophilus) 		PF01795
(Methyltransf_5) 		3 GLY A  32
ASP A  51
ASN A  74
 SAM  A3142 (-3.4A)
SAM  A3142 (-2.8A)
SAM  A3142 (-3.0A)
 0.39A 5jglA-1wg8A:
16.3		 5jglA-1wg8A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9j PROBABLE BUTYRATE
KINASE 2

(Thermotoga
maritima) 		PF00871
(Acetate_kinase) 		3 GLY A  83
ASP A 128
ASN A 157
 None
 0.60A 5jglA-1x9jA:
undetectable		 5jglA-1x9jA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 GLY A 558
ASP A 524
ASN A 228
 None
 0.56A 5jglA-1xkhA:
undetectable		 5jglA-1xkhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9a NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Entamoeba
histolytica) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 GLY A  23
ASP A  26
ASN A 132
 ACT  A1004 ( 4.2A)
None
None
 0.40A 5jglA-1y9aA:
8.0		 5jglA-1y9aA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yaa ASPARTATE
AMINOTRANSFERASE

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		3 GLY A 172
ASP A 169
ASN A 163
 None
 0.39A 5jglA-1yaaA:
undetectable		 5jglA-1yaaA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE

(Candida
tropicalis) 		PF00106
(adh_short) 		3 GLY A  17
ASP A  39
ASN A  74
 None
 0.55A 5jglA-2et6A:
5.7		 5jglA-2et6A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fcr FLAVODOXIN

(Chondrus
crispus) 		PF00258
(Flavodoxin_1) 		3 GLY A  97
ASP A  94
ASN A  12
 None
None
FMN  A 174 (-3.5A)
 0.56A 5jglA-2fcrA:
undetectable		 5jglA-2fcrA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fj3 MAJOR PRION PROTEIN

(Oryctolagus
cuniculus) 		PF00377
(Prion) 		3 GLY A 141
ASP A 146
ASN A 152
 None
 0.61A 5jglA-2fj3A:
undetectable		 5jglA-2fj3A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT

(Stenotrophomonas
maltophilia) 		PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4) 		3 GLY A 960
ASP A 957
ASN A 916
 None
 0.62A 5jglA-2gahA:
undetectable		 5jglA-2gahA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqn PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Helicobacter
pylori) 		PF00486
(Trans_reg_C) 		3 GLY A 200
ASP A 196
ASN A 189
 None
 0.56A 5jglA-2hqnA:
undetectable		 5jglA-2hqnA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1n OUTER MEMBRANE
PROTEIN C

(Escherichia
coli) 		PF00267
(Porin_1) 		3 GLY A 112
ASP A 113
ASN A 333
 None
 0.57A 5jglA-2j1nA:
undetectable		 5jglA-2j1nA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o04 PECTATE LYASE

(Bacillus
subtilis) 		PF00544
(Pec_lyase_C) 		3 GLY A 224
ASP A 184
ASN A 189
 CA  A 402 ( 4.6A)
CA  A 402 (-2.1A)
None
 0.63A 5jglA-2o04A:
undetectable		 5jglA-2o04A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C

(Escherichia
coli) 		PF05175
(MTS)
PF08468
(MTS_N) 		3 GLY A 206
ASP A 227
ASN A 253
 None
 0.43A 5jglA-2pjdA:
16.2		 5jglA-2pjdA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjh NUCLEAR PROTEIN
LOCALIZATION PROTEIN
4 HOMOLOG

(Mus musculus) 		PF11543
(UN_NPL4) 		3 GLY A  72
ASP A  73
ASN A  49
 None
 0.60A 5jglA-2pjhA:
undetectable		 5jglA-2pjhA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pl5 HOMOSERINE
O-ACETYLTRANSFERASE

(Leptospira
interrogans) 		PF00561
(Abhydrolase_1) 		3 GLY A  82
ASP A  86
ASN A  47
 None
 0.55A 5jglA-2pl5A:
undetectable		 5jglA-2pl5A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1q HYALURONOGLUCOSAMINI
DASE

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		3 GLY A 874
ASP A 877
ASN A 933
 None
BTB  A1949 (-2.8A)
None
 0.60A 5jglA-2w1qA:
undetectable		 5jglA-2w1qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xe5 OUTER MEMBRANE PORIN
C

(Escherichia
coli) 		PF00267
(Porin_1) 		3 GLY A 112
ASP A 113
ASN A 330
 None
 0.61A 5jglA-2xe5A:
undetectable		 5jglA-2xe5A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xry DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE

(Methanosarcina
mazei) 		PF00875
(DNA_photolyase) 		3 GLY A 410
ASP A 409
ASN A 266
 FAD  A1463 (-3.4A)
FAD  A1463 (-3.4A)
FAD  A1463 (-4.6A)
 0.57A 5jglA-2xryA:
2.3		 5jglA-2xryA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5x FLAGELLIN

(Salmonella
enterica) 		PF00669
(Flagellin_N)
PF00700
(Flagellin_C)
PF08884
(Flagellin_D3) 		3 GLY A 218
ASP A 219
ASN A 280
 None
 0.48A 5jglA-3a5xA:
undetectable		 5jglA-3a5xA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aje PUTATIVE
UNCHARACTERIZED
PROTEIN ST1526

(Sulfurisphaera
tokodaii) 		PF01300
(Sua5_yciO_yrdC)
PF03481
(SUA5) 		3 GLY A  47
ASP A  46
ASN A  26
 None
 0.57A 5jglA-3ajeA:
undetectable		 5jglA-3ajeA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkx SAM-DEPENDENT
METHYLTRANSFERASE

(Lactobacillus
paracasei) 		PF13649
(Methyltransf_25) 		3 GLY A  52
ASP A  74
ASN A 109
 None
 0.27A 5jglA-3bkxA:
11.9		 5jglA-3bkxA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d43 SPHERICASE

(Lysinibacillus
sphaericus) 		PF00082
(Peptidase_S8) 		3 GLY A  24
ASP A  96
ASN A  46
 None
 0.60A 5jglA-3d43A:
2.1		 5jglA-3d43A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6x (3R)-HYDROXYMYRISTOY
L-[ACYL-CARRIER-PROT
EIN] DEHYDRATASE

(Campylobacter
jejuni) 		PF07977
(FabA) 		3 GLY A 104
ASP A 105
ASN A 132
 None
 0.47A 5jglA-3d6xA:
undetectable		 5jglA-3d6xA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpc NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Entamoeba
histolytica;
Thermoanaerobacter
brockii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 GLY A  23
ASP A  26
ASN A 132
 None
 0.50A 5jglA-3fpcA:
8.1		 5jglA-3fpcA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpl NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Clostridium
beijerinckii;
Thermoanaerobacter
brockii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 GLY A  23
ASP A  26
ASN A 132
 None
 0.51A 5jglA-3fplA:
8.2		 5jglA-3fplA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fsr NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Clostridium
beijerinckii;
Thermoanaerobacter
brockii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 GLY A  23
ASP A  26
ASN A 132
 None
 0.48A 5jglA-3fsrA:
8.4		 5jglA-3fsrA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM

(Serratia
plymuthica) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 GLY A  41
ASP A  36
ASN A  46
 None
 0.58A 5jglA-3gbdA:
undetectable		 5jglA-3gbdA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gue UTP-GLUCOSE-1-PHOSPH
ATE
URIDYLYLTRANSFERASE
2

(Trypanosoma
brucei) 		PF01704
(UDPGP) 		3 GLY A 413
ASP A 412
ASN A 461
 None
 0.55A 5jglA-3gueA:
undetectable		 5jglA-3gueA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxk GOOSE-TYPE LYSOZYME
1

(Gadus morhua) 		PF01464
(SLT) 		3 GLY A 156
ASP A 155
ASN A 126
 None
 0.41A 5jglA-3gxkA:
undetectable		 5jglA-3gxkA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3heb RESPONSE REGULATOR
RECEIVER DOMAIN
PROTEIN (CHEY)

(Rhodospirillum
rubrum) 		PF00072
(Response_reg) 		3 GLY A  18
ASP A  16
ASN A  71
 None
 0.59A 5jglA-3hebA:
3.1		 5jglA-3hebA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hsa PLECKSTRIN HOMOLOGY
DOMAIN

(Shewanella
amazonensis) 		PF08000
(bPH_1) 		3 GLY A 114
ASP A 111
ASN A  10
 MLY  A 117 ( 4.4A)
GOL  A 126 (-3.9A)
None
 0.46A 5jglA-3hsaA:
undetectable		 5jglA-3hsaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hww 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE

(Escherichia
coli) 		PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
PF16582
(TPP_enzyme_M_2) 		3 GLY A 441
ASP A 442
ASN A 494
 AKG  A 557 ( 3.1A)
MG  A 558 ( 2.9A)
None
 0.57A 5jglA-3hwwA:
undetectable		 5jglA-3hwwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1i HOMOSERINE
O-ACETYLTRANSFERASE

(Bacillus
anthracis) 		PF00561
(Abhydrolase_1) 		3 GLY A  75
ASP A  79
ASN A  40
 None
 0.52A 5jglA-3i1iA:
2.4		 5jglA-3i1iA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khp MAOC FAMILY PROTEIN

(Mycobacterium
tuberculosis) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		3 GLY A 148
ASP A 108
ASN A 114
 None
 0.58A 5jglA-3khpA:
undetectable		 5jglA-3khpA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3klj NAD(FAD)-DEPENDENT
DEHYDROGENASE,
NIRB-FAMILY
(N-TERMINAL DOMAIN)

(Clostridium
acetobutylicum) 		PF07992
(Pyr_redox_2) 		3 GLY A 184
ASP A 181
ASN A 317
 None
 0.49A 5jglA-3kljA:
undetectable		 5jglA-3kljA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3la4 UREASE

(Canavalia
ensiformis) 		PF00449
(Urease_alpha)
PF00547
(Urease_gamma)
PF00699
(Urease_beta)
PF01979
(Amidohydro_1) 		3 GLY A 310
ASP A 311
ASN A 372
 None
 0.61A 5jglA-3la4A:
2.1		 5jglA-3la4A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcz O-METHYLTRANSFERASE

(Burkholderia
thailandensis) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		3 GLY A 186
ASP A 207
ASN A 234
 None
 0.41A 5jglA-3mczA:
17.1		 5jglA-3mczA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgg METHYLTRANSFERASE

(Methanosarcina
mazei) 		PF13847
(Methyltransf_31) 		3 GLY A  45
ASP A  66
ASN A  93
 None
 0.17A 5jglA-3mggA:
19.8		 5jglA-3mggA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mvk PROTEIN FUCU

(Bifidobacterium
longum) 		PF05025
(RbsD_FucU) 		3 GLY A  21
ASP A  24
ASN A 121
 None
PGE  A 151 (-4.3A)
None
 0.60A 5jglA-3mvkA:
2.3		 5jglA-3mvkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qlj SHORT CHAIN
DEHYDROGENASE

(Mycobacterium
avium) 		PF00106
(adh_short) 		3 GLY A  15
ASP A  37
ASN A  73
 None
 0.51A 5jglA-3qljA:
6.7		 5jglA-3qljA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qv2 5-CYTOSINE DNA
METHYLTRANSFERASE

(Entamoeba
histolytica) 		PF00145
(DNA_methylase) 		3 GLY A  14
ASP A  37
ASN A  58
 SAH  A 323 (-3.6A)
SAH  A 323 (-2.9A)
SAH  A 323 (-3.1A)
 0.43A 5jglA-3qv2A:
9.9		 5jglA-3qv2A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sm3 SAM-DEPENDENT
METHYLTRANSFERASES

(Methanosarcina
mazei) 		PF08241
(Methyltransf_11) 		3 GLY A  40
ASP A  59
ASN A  91
 None
 0.33A 5jglA-3sm3A:
19.4		 5jglA-3sm3A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL-COENZYME M
REDUCTASE, GAMMA
SUBUNIT

(uncultured
archaeon) 		PF02240
(MCR_gamma) 		3 GLY C 266
ASP C 235
ASN C   8
 None
 0.57A 5jglA-3sqgC:
undetectable		 5jglA-3sqgC:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tht ALKYLATED DNA REPAIR
PROTEIN ALKB HOMOLOG
8

(Homo sapiens) 		PF00076
(RRM_1)
PF13532
(2OG-FeII_Oxy_2) 		3 GLY A 110
ASP A 107
ASN A  49
 None
 0.62A 5jglA-3thtA:
undetectable		 5jglA-3thtA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu2 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME,
CHLOROPLASTIC/AMYLOP
LASTIC

(Oryza sativa) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 GLY A 648
ASP A 640
ASN A 613
 None
 0.54A 5jglA-3vu2A:
undetectable		 5jglA-3vu2A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vvl HOMOSERINE
O-ACETYLTRANSFERASE

(Streptomyces
lavendulae) 		PF00561
(Abhydrolase_1) 		3 GLY A  78
ASP A  82
ASN A  45
 None
 0.59A 5jglA-3vvlA:
undetectable		 5jglA-3vvlA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfl BETA-MANNANASE

(Talaromyces
trachyspermus) 		PF00150
(Cellulase) 		3 GLY A 235
ASP A 236
ASN A 258
 None
None
NAG  A 401 (-1.9A)
 0.58A 5jglA-3wflA:
undetectable		 5jglA-3wflA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wg1 GALACTOSIDE-BINDING
LECTIN

(Agrocybe
aegerita) 		PF00337
(Gal-bind_lectin) 		3 GLY A  26
ASP A  27
ASN A   7
 None
 0.62A 5jglA-3wg1A:
undetectable		 5jglA-3wg1A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wy2 ALPHA-GLUCOSIDASE

(Halomonas sp.
H11) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		3 GLY A  28
ASP A  23
ASN A  33
 None
MG  A 600 (-2.9A)
None
 0.58A 5jglA-3wy2A:
undetectable		 5jglA-3wy2A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4acv PROPHAGE LAMBDALM01,
ANTIGEN B

(Listeria
monocytogenes) 		PF16807
(DUF5072) 		3 GLY B  73
ASP B  70
ASN B  67
 None
 0.63A 5jglA-4acvB:
undetectable		 5jglA-4acvB:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dcm RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G

(Escherichia
coli) 		PF05175
(MTS) 		3 GLY A 238
ASP A 259
ASN A 289
 SAM  A 401 ( 3.7A)
SAM  A 401 (-2.9A)
SAM  A 401 (-4.3A)
 0.50A 5jglA-4dcmA:
17.7		 5jglA-4dcmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecm GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E

(Bacillus
anthracis) 		PF00483
(NTP_transferase) 		3 GLY A 128
ASP A 175
ASN A  99
 None
 0.45A 5jglA-4ecmA:
2.3		 5jglA-4ecmA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evi CONIFERYL ALCOHOL
9-O-METHYLTRANSFERAS
E

(Linum
nodiflorum) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		3 GLY A 210
ASP A 231
ASN A 252
 SAH  A 401 ( 3.8A)
SAH  A 401 (-2.9A)
SAH  A 401 (-3.3A)
 0.37A 5jglA-4eviA:
13.1		 5jglA-4eviA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g7e UREASE

(Cajanus cajan) 		PF00449
(Urease_alpha)
PF00547
(Urease_gamma)
PF00699
(Urease_beta)
PF01979
(Amidohydro_1) 		3 GLY B 310
ASP B 311
ASN B 372
 None
 0.62A 5jglA-4g7eB:
undetectable		 5jglA-4g7eB:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0n DNMT2

(Spodoptera
frugiperda) 		PF00145
(DNA_methylase) 		3 GLY A  11
ASP A  33
ASN A  55
 SAH  A 401 (-3.3A)
SAH  A 401 (-3.1A)
SAH  A 401 (-3.6A)
 0.25A 5jglA-4h0nA:
9.4		 5jglA-4h0nA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 GLY A  68
ASP A  63
ASN A  73
 None
CA  A 701 (-3.2A)
None
 0.60A 5jglA-4hozA:
undetectable		 5jglA-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5h PHENYLACETALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		3 GLY A 168
ASP A 247
ASN A 268
 None
 0.54A 5jglA-4o5hA:
3.7		 5jglA-4o5hA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oja SUPEROXIDE DISMUTASE
[CU-ZN]

(Hydra vulgaris) 		PF00080
(Sod_Cu) 		3 GLY A 126
ASP A 124
ASN A 121
 None
 0.62A 5jglA-4ojaA:
undetectable		 5jglA-4ojaA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1z PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF16215
(DUF4876) 		3 GLY A 354
ASP A 351
ASN A  80
 None
 0.60A 5jglA-4q1zA:
undetectable		 5jglA-4q1zA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wuv 2-HYDROXYCYCLOHEXANE
CARBOXYL-COA
DEHYDROGENASE

(Haemophilus
influenzae) 		PF00106
(adh_short) 		3 GLY A  24
ASP A  46
ASN A  72
 NAD  A 301 (-3.8A)
NAD  A 301 (-2.3A)
NAD  A 301 (-2.8A)
 0.51A 5jglA-4wuvA:
6.7		 5jglA-4wuvA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2

(Vibrio cholerae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		3 GLY A 159
ASP A 160
ASN A  51
 None
 0.57A 5jglA-4x0oA:
undetectable		 5jglA-4x0oA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhp PARM HYBRID FUSION
PROTEIN

(Bacillus
thuringiensis) 		no annotation 3 GLY A 814
ASP A 679
ASN A 702
 ADP  A 903 ( 4.1A)
MG  A 902 (-3.1A)
None
 0.59A 5jglA-4xhpA:
undetectable		 5jglA-4xhpA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xib E3 UBIQUITIN-PROTEIN
LIGASE MIB1

(Homo sapiens) 		PF00569
(ZZ)
PF06701
(MIB_HERC2) 		3 GLY A 171
ASP A 169
ASN A 203
 None
 0.59A 5jglA-4xibA:
undetectable		 5jglA-4xibA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yn5 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE

(Bacillus sp.
JAMB750) 		PF02156
(Glyco_hydro_26) 		3 GLY A 384
ASP A 378
ASN A  95
 None
 0.51A 5jglA-4yn5A:
undetectable		 5jglA-4yn5A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu5 IMMUNE INHIBITOR A,
METALLOPROTEASE

(Bacillus cereus) 		PF05547
(Peptidase_M6) 		3 GLY A 397
ASP A 769
ASN A 764
 None
 0.51A 5jglA-4yu5A:
undetectable		 5jglA-4yu5A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywe PUTATIVE ALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		3 GLY A 141
ASP A 220
ASN A 241
 None
 0.40A 5jglA-4yweA:
3.2		 5jglA-4yweA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmh UNCHARACTERIZED
PROTEIN

(Saccharophagus
degradans) 		PF15979
(Glyco_hydro_115) 		3 GLY A 470
ASP A 471
ASN A 222
 None
NA  A1004 (-3.0A)
None
 0.43A 5jglA-4zmhA:
undetectable		 5jglA-4zmhA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwl BETAINE-ALDEHYDE
DEHYDROGENASE

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		3 GLY A 148
ASP A 227
ASN A 248
 None
 0.40A 5jglA-4zwlA:
3.8		 5jglA-4zwlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzp CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
purpureum) 		PF00840
(Glyco_hydro_7) 		3 GLY A   4
ASP A  73
ASN A  76
 None
 0.60A 5jglA-4zzpA:
undetectable		 5jglA-4zzpA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aek SENTRIN-SPECIFIC
PROTEASE 2

(Homo sapiens) 		PF02902
(Peptidase_C48) 		3 GLY A 400
ASP A 401
ASN A 417
 None
 0.62A 5jglA-5aekA:
undetectable		 5jglA-5aekA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b5s ACETIC ACID

(Talaromyces
cellulolyticus) 		PF13472
(Lipase_GDSL_2) 		3 GLY A   8
ASP A   9
ASN A  95
 None
 0.56A 5jglA-5b5sA:
5.2		 5jglA-5b5sA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN

(Bacteroides
fragilis) 		PF13489
(Methyltransf_23) 		3 GLY A  90
ASP A 109
ASN A 130
 SAH  A 303 ( 3.7A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.27A 5jglA-5bp9A:
12.0		 5jglA-5bp9A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dly PLANTAZOLICIN
METHYLTRANSFERASE
BAML

(Bacillus
velezensis) 		PF13847
(Methyltransf_31) 		3 GLY A  70
ASP A  91
ASN A 113
 SAH  A 301 ( 3.7A)
SAH  A 301 (-2.8A)
SAH  A 301 (-3.8A)
 0.34A 5jglA-5dlyA:
15.1		 5jglA-5dlyA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elz TYPE II PANTOTHENATE
KINASE

(Staphylococcus
aureus) 		PF03630
(Fumble) 		3 GLY A 258
ASP A   6
ASN A  53
 None
MG  A 302 ( 4.1A)
None
 0.51A 5jglA-5elzA:
undetectable		 5jglA-5elzA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS

(Bacillus
halmapalus) 		PF00082
(Peptidase_S8)
PF04151
(PPC) 		3 GLY A 394
ASP A 393
ASN A 400
 CA  A 602 ( 4.4A)
None
None
 0.56A 5jglA-5fbzA:
undetectable		 5jglA-5fbzA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqe BETA-N-ACETYLGALACTO
SAMINIDASE

(Clostridium
perfringens) 		PF13320
(DUF4091) 		3 GLY A 380
ASP A 405
ASN A 402
 None
 0.45A 5jglA-5fqeA:
undetectable		 5jglA-5fqeA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fse UREASE SUBUNIT ALPHA

(Sporosarcina
pasteurii) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		3 GLY C  39
ASP C  40
ASN C 102
 None
 0.62A 5jglA-5fseC:
undetectable		 5jglA-5fseC:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 TRANSLATION
INITIATION FACTOR 1A

(Pyrococcus
abyssi) 		PF01176
(eIF-1a) 		3 GLY 6  44
ASP 6  43
ASN 6  22
 None
 0.47A 5jglA-5jb36:
undetectable		 5jglA-5jb36:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkj ESTERASE E22

(uncultured
bacterium) 		PF00561
(Abhydrolase_1) 		3 GLY A  98
ASP A 102
ASN A  63
 None
 0.48A 5jglA-5jkjA:
undetectable		 5jglA-5jkjA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lir SIGMA CROSS-REACTING
PROTEIN 27A
(SCRP-27A)

(Salmonella
enterica) 		PF01965
(DJ-1_PfpI) 		3 GLY A  19
ASP A  18
ASN A  53
 None
 0.61A 5jglA-5lirA:
undetectable		 5jglA-5lirA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m41 NIGRITOXINE

(Vibrio
nigripulchritudo) 		no annotation 3 GLY A 416
ASP A 387
ASN A 384
 None
 0.39A 5jglA-5m41A:
undetectable		 5jglA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdq CHITOPORIN

(Vibrio harveyi) 		no annotation 3 GLY A 131
ASP A 132
ASN A 336
 None
 0.61A 5jglA-5mdqA:
undetectable		 5jglA-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpt CITRININ POLYKETIDE
SYNTHASE

(Monascus
purpureus) 		PF08242
(Methyltransf_12) 		3 GLY A1994
ASP A2019
ASN A2044
 SAH  A2201 (-3.0A)
SAH  A2201 (-2.0A)
SAH  A2201 (-2.8A)
 0.35A 5jglA-5mptA:
19.0		 5jglA-5mptA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mvh BACCELL_00856

(Bacteroides
cellulosilyticus) 		PF15892
(BNR_4) 		3 GLY A 152
ASP A 153
ASN A 181
 None
 0.56A 5jglA-5mvhA:
undetectable		 5jglA-5mvhA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n11 HEMAGGLUTININ-ESTERA
SE

(Betacoronavirus
1) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		3 GLY A 332
ASP A 330
ASN A 327
 None
 0.38A 5jglA-5n11A:
undetectable		 5jglA-5n11A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8o HOMOSERINE
O-ACETYLTRANSFERASE

(Mycolicibacterium
hassiacum) 		PF00561
(Abhydrolase_1) 		3 GLY A  87
ASP A  91
ASN A  52
 None
 0.57A 5jglA-5w8oA:
undetectable		 5jglA-5w8oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8p HOMOSERINE
O-ACETYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF00561
(Abhydrolase_1) 		3 GLY A  90
ASP A  94
ASN A  55
 None
 0.62A 5jglA-5w8pA:
undetectable		 5jglA-5w8pA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdu ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 3 GLY G 367
ASP G 368
ASN G 425
 None
 0.51A 5jglA-5wduG:
undetectable		 5jglA-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xd6 PROTEIN KINASE
SUPERFAMILY PROTEIN

(Arabidopsis
thaliana) 		no annotation 3 GLY A 272
ASP A 305
ASN A 309
 None
 0.50A 5jglA-5xd6A:
undetectable		 5jglA-5xd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhw PUTATIVE
6-DEOXY-D-MANNOHEPTO
SE PATHWAY PROTEIN

(Yersinia
pseudotuberculosis) 		no annotation 3 GLY A 212
ASP A 210
ASN A 166
 None
 0.59A 5jglA-5xhwA:
undetectable		 5jglA-5xhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cet GATOR COMPLEX
PROTEIN DEPDC5

(Homo sapiens) 		no annotation 3 GLY D 188
ASP D 189
ASN D 197
 None
 0.59A 5jglA-6cetD:
undetectable		 5jglA-6cetD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus) 		no annotation 3 GLY A 407
ASP A 408
ASN A  47
 None
 0.63A 5jglA-6eoeA:
undetectable		 5jglA-6eoeA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f91 PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLY A 257
ASP A 316
ASN A 336
 None
 0.55A 5jglA-6f91A:
undetectable		 5jglA-6f91A:
undetectable