SIMILAR PATTERNS OF AMINO ACIDS FOR 5JCN_B_ASCB502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8a PROTEIN
(ASPARTYL-TRNA
SYNTHETASE)

(Thermococcus
kodakarensis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 GLU A 233
GLY A 404
ARG A 368
PHE A 353
 None
 1.18A 5jcnB-1b8aA:
0.0		 5jcnB-1b8aA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csj HEPATITIS C VIRUS
RNA POLYMERASE
(NS5B)

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 GLU A 236
GLY A 290
ARG A 280
PHE A 224
 None
 0.98A 5jcnB-1csjA:
undetectable		 5jcnB-1csjA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gtk PORPHOBILINOGEN
DEAMINASE

(Escherichia
coli) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		4 GLU A 231
PRO A 194
GLY A 197
ARG A 101
 None
 1.19A 5jcnB-1gtkA:
0.3		 5jcnB-1gtkA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyg L-LACTATE/MALATE
DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 GLU A 177
PRO A 124
GLY A 179
ARG A  86
 None
 1.41A 5jcnB-1hygA:
0.2		 5jcnB-1hygA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ixk METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF01189
(Methyltr_RsmB-F)
PF17125
(Methyltr_RsmF_N) 		4 GLU A 255
PRO A 282
ARG A 296
ARG A  23
 None
 1.41A 5jcnB-1ixkA:
3.2		 5jcnB-1ixkA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rqg METHIONYL-TRNA
SYNTHETASE

(Pyrococcus
abyssi) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 GLU A 222
GLY A 223
PHE A 306
ARG A 227
 None
 1.19A 5jcnB-1rqgA:
2.3		 5jcnB-1rqgA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3q QUINOLINE
2-OXIDOREDUCTASE
LARGE SUBUNIT

(Pseudomonas
putida) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 GLU B 202
PRO B 200
GLY B 252
PHE B 255
 None
None
None
MCN  B4921 ( 3.8A)
 1.45A 5jcnB-1t3qB:
undetectable		 5jcnB-1t3qB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ven BETA-AMYLASE

(Bacillus cereus) 		PF00686
(CBM_20)
PF01373
(Glyco_hydro_14) 		4 GLU A 121
PRO A 307
GLY A 237
ARG A 189
 None
 1.22A 5jcnB-1venA:
0.4		 5jcnB-1venA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w85 PYRUVATE
DEHYDROGENASE E1
COMPONENT, ALPHA
SUBUNIT

(Geobacillus
stearothermophilus) 		PF00676
(E1_dh) 		4 GLU A  82
GLY A  80
ARG A  57
ARG A 298
 None
 1.43A 5jcnB-1w85A:
undetectable		 5jcnB-1w85A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc6 BETA-GALACTOSIDASE

(Penicillium sp.) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 GLU A 846
PRO A 106
GLY A 725
ARG A 154
 None
 1.48A 5jcnB-1xc6A:
undetectable		 5jcnB-1xc6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdz METHYLTRANSFERASE
GIDB

(Bacillus
subtilis) 		PF02527
(GidB) 		4 GLU A 129
GLY A 230
ARG A 127
ARG A 151
 None
 1.47A 5jcnB-1xdzA:
undetectable		 5jcnB-1xdzA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8x UBIQUITIN-CONJUGATIN
G ENZYME E2 M

(Homo sapiens) 		PF00179
(UQ_con) 		4 PRO A 139
GLY A  69
PHE A 160
ARG A 157
 None
 0.93A 5jcnB-1y8xA:
undetectable		 5jcnB-1y8xA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE, B
SUBUNIT

(Methylococcus
capsulatus) 		PF04744
(Monooxygenase_B) 		4 GLU A  79
PRO A  78
PHE A  41
ARG A 386
 None
 1.49A 5jcnB-1yewA:
undetectable		 5jcnB-1yewA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yw4 SUCCINYLGLUTAMATE
DESUCCINYLASE

(Chromobacterium
violaceum) 		PF04952
(AstE_AspA) 		4 GLU A  38
GLY A  41
ARG A  30
ARG A  44
 None
 1.44A 5jcnB-1yw4A:
undetectable		 5jcnB-1yw4A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3n PUTATIVE
GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF01380
(SIS) 		4 GLU A 220
PRO A 309
GLY A 219
PHE A  63
 None
 1.31A 5jcnB-2a3nA:
undetectable		 5jcnB-2a3nA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aey FRUCTAN
1-EXOHYDROLASE IIA

(Cichorium
intybus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 GLU A 295
GLY A 309
ARG A 495
ARG A   8
 None
 1.45A 5jcnB-2aeyA:
undetectable		 5jcnB-2aeyA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2as0 HYPOTHETICAL PROTEIN
PH1915

(Pyrococcus
horikoshii) 		PF01472
(PUA)
PF10672
(Methyltrans_SAM) 		4 PRO A 110
GLY A  52
PHE A  78
ARG A  81
 None
 1.17A 5jcnB-2as0A:
3.0		 5jcnB-2as0A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bkw ALANINE-GLYOXYLATE
AMINOTRANSFERASE 1

(Saccharomyces
cerevisiae) 		PF00266
(Aminotran_5) 		4 GLY A 343
ARG A 354
PHE A  97
ARG A 100
 None
GLV  A1384 (-2.5A)
PLP  A1201 (-4.1A)
None
 1.14A 5jcnB-2bkwA:
undetectable		 5jcnB-2bkwA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy8 D-PHENYLGLYCINE
AMINOTRANSFERASE

(Pseudomonas
stutzeri) 		PF00202
(Aminotran_3) 		4 GLU A 242
PRO A 209
GLY A 246
PHE A 214
 None
 1.35A 5jcnB-2cy8A:
1.3		 5jcnB-2cy8A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gbx BIPHENYL
2,3-DIOXYGENASE
ALPHA SUBUNIT

(Sphingobium
yanoikuyae) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 GLU A 163
GLY A 398
PHE A 440
ARG A 443
 None
 1.40A 5jcnB-2gbxA:
undetectable		 5jcnB-2gbxA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjn HYPOTHETICAL PROTEIN
PA1024

(Pseudomonas
aeruginosa) 		PF03060
(NMO) 		4 GLU A 155
PRO A 153
ARG A 233
PHE A 147
 None
 1.15A 5jcnB-2gjnA:
undetectable		 5jcnB-2gjnA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iik 3-KETOACYL-COA
THIOLASE,
PEROXISOMAL

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLU A 394
ARG A 397
PHE A 220
ARG A 386
 None
 1.42A 5jcnB-2iikA:
undetectable		 5jcnB-2iikA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ip4 PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Thermus
thermophilus) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 GLU A  12
PRO A  32
GLY A   9
ARG A 359
 None
 1.27A 5jcnB-2ip4A:
3.7		 5jcnB-2ip4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jm3 HYPOTHETICAL PROTEIN

(Caenorhabditis
elegans) 		PF05485
(THAP) 		4 GLU A  64
PRO A  78
GLY A  65
PHE A  14
 None
 1.24A 5jcnB-2jm3A:
undetectable		 5jcnB-2jm3A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kro CD2-ASSOCIATED
PROTEIN

(Mus musculus) 		PF00018
(SH3_1) 		4 GLU A  22
PRO A  56
GLY A  17
PHE A  59
 None
 1.22A 5jcnB-2kroA:
undetectable		 5jcnB-2kroA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kwo ZINC FINGER PROTEIN
DPF3
HISTONE PEPTIDE

(Homo sapiens;
Homo sapiens) 		PF00628
(PHD)
no annotation 		4 GLU A 315
GLY B   4
ARG A 289
PHE A 264
 None
SAC  B   1 ( 4.8A)
SAC  B   1 ( 4.1A)
SAC  B   1 ( 3.8A)
 1.16A 5jcnB-2kwoA:
undetectable		 5jcnB-2kwoA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu NEDD8-CONJUGATING
ENZYME UBC12

(Homo sapiens) 		PF00179
(UQ_con) 		4 PRO C 139
GLY C  69
PHE C 160
ARG C 157
 None
 0.90A 5jcnB-2nvuC:
undetectable		 5jcnB-2nvuC:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o62 HYPOTHETICAL PROTEIN

(Nostoc
punctiforme) 		PF12204
(DUF3598) 		4 GLU A 133
PRO A 215
ARG A 123
PHE A  22
 None
 1.37A 5jcnB-2o62A:
undetectable		 5jcnB-2o62A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogj DIHYDROOROTASE

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1) 		4 GLU A 148
PRO A 147
ARG A 177
ARG A 145
 None
 1.40A 5jcnB-2ogjA:
undetectable		 5jcnB-2ogjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okj GLUTAMATE
DECARBOXYLASE 1

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 PRO A 508
GLY A 351
PHE A 504
ARG A 316
 None
 1.19A 5jcnB-2okjA:
undetectable		 5jcnB-2okjA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p8t HYPOTHETICAL PROTEIN
PH0730

(Pyrococcus
horikoshii) 		PF14544
(DUF4443) 		4 GLU A  86
PRO A  87
ARG A  77
ARG A  39
 None
 1.24A 5jcnB-2p8tA:
undetectable		 5jcnB-2p8tA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE
NRFC PROTEIN

(Thermus
thermophilus;
Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
PF13247
(Fer4_11) 		4 GLU A  69
GLY A  76
ARG A  77
ARG B 122
 None
 1.50A 5jcnB-2vpwA:
undetectable		 5jcnB-2vpwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wp8 EXOSOME COMPLEX
EXONUCLEASE DIS3

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF13638
(PIN_4)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		4 GLU J 506
GLY J 507
PHE J 576
ARG J 621
 None
 1.45A 5jcnB-2wp8J:
undetectable		 5jcnB-2wp8J:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpz LEUKOTRIENE A-4
HYDROLASE

(Saccharomyces
cerevisiae) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 GLU A 430
GLY A 390
ARG A 371
PHE A 505
 None
 1.05A 5jcnB-2xpzA:
undetectable		 5jcnB-2xpzA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xym RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 GLU A 236
GLY A 290
ARG A 280
PHE A 224
 None
 1.10A 5jcnB-2xymA:
undetectable		 5jcnB-2xymA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1o EUGENOL SYNTHASE

(Clarkia breweri) 		PF05368
(NmrA) 		4 GLU A 189
PRO A 310
GLY A 154
PHE A 304
 None
 1.41A 5jcnB-3c1oA:
5.9		 5jcnB-3c1oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica) 		PF00797
(Acetyltransf_2) 		4 PRO A 245
GLY A 159
PHE A 227
ARG A 141
 None
 1.33A 5jcnB-3d9wA:
undetectable		 5jcnB-3d9wA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 PRO A 585
GLY A 580
PHE A 107
ARG A 192
 None
 1.16A 5jcnB-3decA:
undetectable		 5jcnB-3decA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fed GLUTAMATE
CARBOXYPEPTIDASE III

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 GLU A 142
PRO A 137
GLY A 140
PHE A 373
 None
 1.13A 5jcnB-3fedA:
undetectable		 5jcnB-3fedA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fot 15-O-ACETYLTRANSFERA
SE

(Fusarium
sporotrichioides) 		PF07428
(Tri3) 		4 GLU A  37
ARG A  31
PHE A 353
ARG A 342
 None
 1.31A 5jcnB-3fotA:
undetectable		 5jcnB-3fotA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gaz ALCOHOL
DEHYDROGENASE
SUPERFAMILY PROTEIN

(Novosphingobium
aromaticivorans) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLU A 283
GLY A 282
ARG A 286
PHE A  85
 None
 1.18A 5jcnB-3gazA:
3.4		 5jcnB-3gazA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq9 PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 GLU A 216
GLY A 210
ARG A 173
ARG A 301
 None
 1.39A 5jcnB-3gq9A:
undetectable		 5jcnB-3gq9A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsz RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 GLU A 236
GLY A 290
ARG A 280
PHE A 224
 None
 1.05A 5jcnB-3gszA:
undetectable		 5jcnB-3gszA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hoa THERMOSTABLE
CARBOXYPEPTIDASE 1

(Thermus
thermophilus) 		PF02074
(Peptidase_M32) 		4 PRO A 154
GLY A 175
ARG A 177
ARG A  96
 None
 1.19A 5jcnB-3hoaA:
undetectable		 5jcnB-3hoaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ijp DIHYDRODIPICOLINATE
REDUCTASE

(Bartonella
henselae) 		PF01113
(DapB_N)
PF05173
(DapB_C) 		4 GLU A 149
GLY A 202
ARG A 189
ARG A 177
 None
 1.37A 5jcnB-3ijpA:
4.3		 5jcnB-3ijpA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1

(Sulfolobus
solfataricus;
Sulfolobus
solfataricus) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		4 GLU B 106
PRO A   5
GLY A 238
ARG B  71
 None
 1.45A 5jcnB-3l7zB:
undetectable		 5jcnB-3l7zB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3md0 ARGININE/ORNITHINE
TRANSPORT SYSTEM
ATPASE

(Mycobacterium
tuberculosis) 		PF03308
(ArgK) 		4 GLU A 147
GLY A  56
ARG A  60
PHE A 270
 None
 1.29A 5jcnB-3md0A:
2.2		 5jcnB-3md0A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poy NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 GLU A 535
GLY A 717
ARG A 715
ARG A 733
 None
 1.34A 5jcnB-3poyA:
undetectable		 5jcnB-3poyA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psf TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		4 GLU A 387
PRO A 389
GLY A 953
ARG A 325
 None
 0.93A 5jcnB-3psfA:
undetectable		 5jcnB-3psfA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		4 GLU A 387
PRO A 389
GLY A 953
ARG A 325
 None
 0.91A 5jcnB-3psiA:
undetectable		 5jcnB-3psiA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qcw NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 GLU A 519
GLY A 701
ARG A 699
ARG A 717
 None
 1.15A 5jcnB-3qcwA:
undetectable		 5jcnB-3qcwA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgh RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 GLU A 236
GLY A 290
ARG A 280
PHE A 224
 None
 1.06A 5jcnB-3qghA:
undetectable		 5jcnB-3qghA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9x RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Aquifex
aeolicus) 		PF00398
(RrnaAD) 		4 GLY B 138
ARG B 150
PHE B 201
ARG B 204
 None
 1.40A 5jcnB-3r9xB:
2.4		 5jcnB-3r9xB:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slc ACETATE KINASE

(Salmonella
enterica) 		PF00871
(Acetate_kinase) 		4 PRO A 234
GLY A 214
ARG A 243
ARG A  91
 None
 1.45A 5jcnB-3slcA:
undetectable		 5jcnB-3slcA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 GLU A 216
GLY A 210
ARG A 173
ARG A 301
 None
 1.43A 5jcnB-3sucA:
undetectable		 5jcnB-3sucA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tex PROTECTIVE ANTIGEN

(Bacillus
anthracis) 		PF03495
(Binary_toxB)
PF07691
(PA14)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		4 PRO A 154
GLY A 182
PHE A 464
ARG A 242
 None
 1.46A 5jcnB-3texA:
undetectable		 5jcnB-3texA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v3k PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815

(Escherichia
coli) 		PF16809
(NleF_casp_inhib) 		4 GLU B  27
PRO B 177
GLY B  96
ARG B  80
 None
 1.47A 5jcnB-3v3kB:
undetectable		 5jcnB-3v3kB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1

(Toxoplasma
gondii) 		PF01150
(GDA1_CD39) 		4 GLU A 465
GLY A 233
ARG A 192
ARG A 229
 None
 1.49A 5jcnB-4a5aA:
undetectable		 5jcnB-4a5aA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4d FERREDOXIN-NADP
REDUCTASE

(Xanthomonas
citri) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 GLU A 158
PRO A 179
ARG A 154
PHE A 186
 None
 1.20A 5jcnB-4b4dA:
2.3		 5jcnB-4b4dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dns FAD-LINKED
OXIDOREDUCTASE BG60

(Cynodon
dactylon) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 PRO A 387
GLY A 163
PHE A 467
ARG A 390
 None
 1.44A 5jcnB-4dnsA:
undetectable		 5jcnB-4dnsA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3y DIHYDRODIPICOLINATE
REDUCTASE

(Burkholderia
thailandensis) 		PF01113
(DapB_N)
PF05173
(DapB_C) 		4 GLU A 151
GLY A 204
ARG A 198
ARG A 181
 None
 1.48A 5jcnB-4f3yA:
4.3		 5jcnB-4f3yA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fie SERINE/THREONINE-PRO
TEIN KINASE PAK 4

(Homo sapiens) 		PF00069
(Pkinase)
PF00786
(PBD) 		4 GLU A 495
PRO A 557
GLY A 493
ARG A 471
 None
 1.20A 5jcnB-4fieA:
undetectable		 5jcnB-4fieA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ihe THNT PROTEIN

(Streptomyces
cattleya) 		PF03576
(Peptidase_S58) 		4 GLU A 173
GLY A  40
ARG A 332
ARG A 123
 None
 1.10A 5jcnB-4iheA:
undetectable		 5jcnB-4iheA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A

(Mus musculus) 		PF13516
(LRR_6) 		4 GLU A 411
PRO A 413
ARG A 407
PHE A 404
 None
 1.37A 5jcnB-4k17A:
undetectable		 5jcnB-4k17A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4otd SERINE/THREONINE-PRO
TEIN KINASE N1

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		4 GLU A 818
PRO A 841
GLY A 817
PHE A 843
 None
 1.39A 5jcnB-4otdA:
undetectable		 5jcnB-4otdA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pht TYPE II SECRETION
SYSTEM PROTEIN L

(Vibrio
vulnificus) 		PF05134
(T2SSL) 		4 GLU X 156
PRO X  16
GLY X 155
ARG X   8
 None
 1.42A 5jcnB-4phtX:
undetectable		 5jcnB-4phtX:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rih GLYCOSYL TRANSFERASE
HOMOLOG,GLYCOSYL
TRANSFERASE

(Streptomyces
fradiae;
Streptomyces
cyanogenus) 		PF06722
(DUF1205) 		4 GLU A  80
GLY A 305
PHE A 223
ARG A 220
 None
None
None
3R2  A 401 (-3.7A)
 1.41A 5jcnB-4rihA:
2.7		 5jcnB-4rihA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3n 2'-5'-OLIGOADENYLATE
SYNTHASE 3

(Homo sapiens) 		PF10421
(OAS1_C) 		4 PRO A 301
GLY A 178
PHE A 283
ARG A 290
 None
 1.50A 5jcnB-4s3nA:
undetectable		 5jcnB-4s3nA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uis GAMMA-SECRETASE

(Homo sapiens) 		PF05450
(Nicastrin) 		4 GLU A 333
PRO A 424
ARG A 281
PHE A 448
 None
 1.46A 5jcnB-4uisA:
undetectable		 5jcnB-4uisA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqz HSIE1

(Pseudomonas
aeruginosa) 		PF07024
(ImpE) 		4 GLU A 238
PRO A 261
ARG A 178
ARG A 265
 None
 1.42A 5jcnB-4uqzA:
undetectable		 5jcnB-4uqzA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 GLU M 107
PRO M 110
PHE M 129
ARG M 133
 None
 1.15A 5jcnB-4wj3M:
undetectable		 5jcnB-4wj3M:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xbr PROTEIN
FAM212A,SERINE/THREO
NINE-PROTEIN KINASE
PAK 4

(Homo sapiens) 		PF00069
(Pkinase)
PF15342
(FAM212) 		4 GLU A 495
PRO A 557
GLY A 493
ARG A 471
 None
 1.19A 5jcnB-4xbrA:
undetectable		 5jcnB-4xbrA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye4 HT593.1 GP120
LIGHT CHAIN OF HJ16

(Human
immunodeficiency
virus;
Homo sapiens) 		PF00516
(GP120)
PF07654
(C1-set)
PF07686
(V-set) 		4 PRO L  33
GLY G 459
ARG L  99
ARG G 456
 NAG  G 503 (-3.8A)
None
None
None
 1.44A 5jcnB-4ye4L:
undetectable		 5jcnB-4ye4L:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fm5 OBSCURIN-LIKE-1

(Homo sapiens) 		PF07679
(I-set) 		4 GLU O 282
GLY O 315
ARG O 314
ARG O 292
 None
 1.32A 5jcnB-5fm5O:
undetectable		 5jcnB-5fm5O:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT

(Escherichia
coli;
Escherichia
coli) 		PF00111
(Fer2)
PF01799
(Fer2_2)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 GLU A 198
PRO A 192
ARG A 202
ARG B  85
 None
 1.43A 5jcnB-5g5gA:
undetectable		 5jcnB-5g5gA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gve DNA TOPOISOMERASE
3-BETA-1

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 GLU A 123
GLY A 122
ARG A 149
PHE A 152
 None
MG  A 701 ( 4.9A)
None
None
 1.37A 5jcnB-5gveA:
undetectable		 5jcnB-5gveA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6o PORPHOBILINOGEN
DEAMINASE

(Vibrio cholerae) 		no annotation 4 GLU A 237
PRO A 200
GLY A 203
ARG A 107
 None
 1.23A 5jcnB-5h6oA:
undetectable		 5jcnB-5h6oA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy7 PUTATIVE PRE-MRNA
SPLICING PROTEIN

(Chaetomium
thermophilum) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 GLU A 943
PRO A 944
GLY A 960
ARG A 914
 None
 1.41A 5jcnB-5hy7A:
undetectable		 5jcnB-5hy7A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1f PLECTIN,PLECTIN

(Homo sapiens) 		no annotation 4 GLY A 972
ARG A 780
PHE A 963
ARG A 978
 None
 1.18A 5jcnB-5j1fA:
undetectable		 5jcnB-5j1fA:
17.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jcn OS09G0567300 PROTEIN

(Oryza sativa) 		PF07992
(Pyr_redox_2) 		6 GLU A  47
PRO A  49
GLY A  72
ARG A 320
PHE A 349
ARG A 351
 None
FAD  A 500 ( 3.6A)
ASC  A 502 (-4.0A)
ASC  A 502 (-2.8A)
FAD  A 500 (-3.7A)
ASC  A 502 (-4.0A)
 0.15A 5jcnB-5jcnA:
62.6		 5jcnB-5jcnA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT

(Escherichia
coli) 		PF03814
(KdpA) 		4 GLU A  56
GLY A 164
ARG A 157
ARG A 172
 None
 0.92A 5jcnB-5mrwA:
undetectable		 5jcnB-5mrwA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ov6 PORPHOBILINOGEN
DEAMINASE

(Bacillus
megaterium) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		4 GLU A 230
PRO A 193
GLY A 196
ARG A  99
 None
 1.23A 5jcnB-5ov6A:
undetectable		 5jcnB-5ov6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tir SUPEROXIDE DISMUTASE

(Trichoderma
reesei) 		no annotation 4 GLU A 156
PRO A 158
GLY A 155
PHE A 205
 None
 0.99A 5jcnB-5tirA:
undetectable		 5jcnB-5tirA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tky PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF00012
(HSP70) 		4 GLU A 319
PRO A 320
GLY A 316
PHE A 209
 None
 1.30A 5jcnB-5tkyA:
undetectable		 5jcnB-5tkyA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u30 CRISPR-ASSOCIATED
ENDONUCLEASE C2C1

(Alicyclobacillus
acidoterrestris) 		no annotation 4 GLU A 956
GLY A 957
ARG A 574
ARG A 900
 None
 1.38A 5jcnB-5u30A:
undetectable		 5jcnB-5u30A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue2 MATRILYSIN

(Homo sapiens) 		PF00413
(Peptidase_M10)
PF01471
(PG_binding_1) 		4 GLU A 176
GLY A 153
PHE A  22
ARG A  21
 CA  A 302 (-3.4A)
CA  A 302 (-4.5A)
None
SGN  A 305 (-3.5A)
 1.34A 5jcnB-5ue2A:
undetectable		 5jcnB-5ue2A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE

(Neisseria
meningitidis) 		no annotation 4 GLU A 151
GLY A 204
ARG A 191
ARG A 181
 None
 1.26A 5jcnB-5ugjA:
4.0		 5jcnB-5ugjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vef SERINE/THREONINE-PRO
TEIN KINASE PAK 4

(Homo sapiens) 		no annotation 4 GLU A 495
PRO A 557
GLY A 493
ARG A 471
 None
 1.20A 5jcnB-5vefA:
undetectable		 5jcnB-5vefA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5veh KYNURENINE
AMINOTRANSFERASE

(Aedes aegypti) 		no annotation 4 GLU A  29
PRO A 387
PHE A 391
ARG A 405
 None
 1.49A 5jcnB-5vehA:
undetectable		 5jcnB-5vehA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8g 2-SUCCINYLBENZOATE--
COA LIGASE

(Bacillus
subtilis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PRO A 159
GLY A 161
ARG A 350
PHE A  94
 None
 1.46A 5jcnB-5x8gA:
undetectable		 5jcnB-5x8gA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yhh UNCHARACTERIZED
CONSERVED PROTEIN
YIIM

(Geobacillus
stearothermophilus) 		no annotation 4 GLU A  65
PRO A  63
GLY A  91
PHE A 143
 None
 1.32A 5jcnB-5yhhA:
undetectable		 5jcnB-5yhhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6any BM4233, ISOFORM B

(Brugia malayi) 		no annotation 4 GLU A  72
GLY A  22
ARG A  29
ARG A 112
 None
 1.29A 5jcnB-6anyA:
undetectable		 5jcnB-6anyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6arr ACETYL-COA
ACETYLTRANSFERASE

(Aspergillus
fumigatus) 		no annotation 4 PRO A 225
GLY A 348
PHE A 199
ARG A  14
 None
 1.39A 5jcnB-6arrA:
undetectable		 5jcnB-6arrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byi BETA-MANNOSIDASE

(Xanthomonas
citri) 		no annotation 4 PRO A 209
GLY A 411
PHE A 144
ARG A 206
 None
 1.42A 5jcnB-6byiA:
undetectable		 5jcnB-6byiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4n PSEUDOPALINE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		no annotation 4 PRO A 250
GLY A 225
PHE A 345
ARG A 231
 None
 1.02A 5jcnB-6c4nA:
undetectable		 5jcnB-6c4nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emk SERINE/THREONINE-PRO
TEIN KINASE TOR2

(Saccharomyces
cerevisiae) 		no annotation 4 GLU A2203
ARG A2193
PHE A2185
ARG A2317
 None
 1.33A 5jcnB-6emkA:
undetectable		 5jcnB-6emkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eno DEHYDRATASE FAMILY
PROTEIN

(Carboxydothermus
hydrogenoformans) 		no annotation 4 GLU A 305
GLY A 304
ARG A 221
PHE A 314
 None
 1.40A 5jcnB-6enoA:
2.4		 5jcnB-6enoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 7

(Mus musculus) 		no annotation 4 PRO o  26
GLY o  29
ARG o 103
ARG o 114
 None
 1.40A 5jcnB-6g2jo:
undetectable		 5jcnB-6g2jo:
undetectable