SIMILAR PATTERNS OF AMINO ACIDS FOR 5J4N_A_AG2A501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1abr ABRIN-A

(Abrus
precatorius) 		PF00652
(Ricin_B_lectin) 		4 SER B  64
GLY B  32
ASN B  31
ILE B  39
 None
 1.01A 5j4nA-1abrB:
undetectable		 5j4nA-1abrB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b1y PROTEIN
(BETA-AMYLASE)

(Hordeum vulgare) 		PF01373
(Glyco_hydro_14) 		4 SER A 193
GLY A  94
ASN A  96
ILE A 130
 None
None
GLC  A 550 (-4.4A)
None
 1.04A 5j4nA-1b1yA:
0.0		 5j4nA-1b1yA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgj ALDEHYDE
OXIDOREDUCTASE

(Desulfovibrio
desulfuricans) 		PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2) 		4 SER A  35
GLY A  78
ASN A   9
ILE A 108
 None
 1.12A 5j4nA-1dgjA:
0.0		 5j4nA-1dgjA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		4 SER A 314
GLY A 197
ASN A 198
MET A 302
 None
 1.14A 5j4nA-1dl5A:
0.0		 5j4nA-1dl5A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e7s GDP-FUCOSE
SYNTHETASE

(Escherichia
coli) 		PF01370
(Epimerase) 		4 SER A 221
GLY A 246
MET A 217
ILE A 243
 None
 1.16A 5j4nA-1e7sA:
0.0		 5j4nA-1e7sA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f4h BETA-GALACTOSIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 SER A 933
GLY A 936
ASN A 958
ILE A 993
 None
 1.16A 5j4nA-1f4hA:
0.0		 5j4nA-1f4hA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl6 ATPASE

(Escherichia
coli) 		PF10412
(TrwB_AAD_bind) 		4 GLY A 161
ASN A 160
ILE A 315
TRP A 317
 None
 0.88A 5j4nA-1gl6A:
0.0		 5j4nA-1gl6A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h71 SERRALYSIN

(Pseudomonas sp.
'TAC II 18') 		PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		4 SER P 306
GLY P 339
ASN P 340
ILE P 300
 None
CA  P 505 ( 4.7A)
None
None
 0.90A 5j4nA-1h71P:
0.0		 5j4nA-1h71P:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg8 ENDOPOLYGALACTURONAS
E

(Fusarium
verticillioides) 		PF00295
(Glyco_hydro_28) 		4 SER A 362
GLY A 295
ILE A 338
TRP A 336
 None
 1.15A 5j4nA-1hg8A:
undetectable		 5j4nA-1hg8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkh GAMMA LACTAMASE

(Microbacterium) 		PF00561
(Abhydrolase_1) 		4 SER A  65
GLY A   6
ASN A   7
ILE A   3
 None
 0.95A 5j4nA-1hkhA:
undetectable		 5j4nA-1hkhA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzh IMMUNOGLOBULIN HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER H  30
GLY H  55
ASN H  54
ILE H  34
 None
 1.04A 5j4nA-1hzhH:
undetectable		 5j4nA-1hzhH:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka0 HALOTOLERANCE
PROTEIN HAL2

(Saccharomyces
cerevisiae) 		PF00459
(Inositol_P) 		4 SER A  75
GLY A 128
ASN A 129
ILE A 124
 None
 0.94A 5j4nA-1ka0A:
0.0		 5j4nA-1ka0A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mcw IMMUNOGLOBULIN WEIR
(LIGHT CHAIN)

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER W  21
GLY W  70
ASN W  71
ILE W  35
 None
 1.07A 5j4nA-1mcwW:
undetectable		 5j4nA-1mcwW:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)

(Ascophyllum
nodosum) 		no annotation 4 SER A 416
GLY A 423
ASN A 422
ILE A 492
 VO4  A 600 (-2.8A)
None
None
None
 1.11A 5j4nA-1qi9A:
undetectable		 5j4nA-1qi9A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qon ACETYLCHOLINESTERASE

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 SER A 241
GLY A 362
ASN A 363
ILE A 359
 None
 0.88A 5j4nA-1qonA:
undetectable		 5j4nA-1qonA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Halothiobacillus
neapolitanus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 SER A 445
GLY A 409
ASN A 413
ILE A 450
 None
 1.02A 5j4nA-1svdA:
undetectable		 5j4nA-1svdA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ta3 ENDO-1,4-BETA-XYLANA
SE

(Aspergillus
nidulans) 		PF00331
(Glyco_hydro_10) 		4 SER B  45
GLY B  79
MET B  46
ILE B  40
 None
 1.09A 5j4nA-1ta3B:
undetectable		 5j4nA-1ta3B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ups GLCNAC-ALPHA-1,4-GAL
-RELEASING
ENDO-BETA-GALACTOSID
ASE

(Clostridium
perfringens) 		PF00722
(Glyco_hydro_16) 		4 SER A 138
GLY A 143
ASN A 262
ILE A  78
 None
 1.16A 5j4nA-1upsA:
undetectable		 5j4nA-1upsA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		4 SER J 132
GLY J 340
ASN J 341
ILE J 234
 None
 0.62A 5j4nA-1wcdJ:
undetectable		 5j4nA-1wcdJ:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A

(Ruminiclostridium
thermocellum) 		PF00963
(Cohesin) 		4 SER A 139
GLY A 146
MET A 140
ILE A  92
 None
 1.15A 5j4nA-2bm3A:
undetectable		 5j4nA-2bm3A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ee2 CONTACTIN-1

(Homo sapiens) 		PF00041
(fn3) 		4 SER A 103
GLY A  26
ILE A  52
TRP A  39
 None
 1.05A 5j4nA-2ee2A:
undetectable		 5j4nA-2ee2A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwz 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE

(Homo sapiens) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 SER A 117
GLY A 279
MET A 121
ILE A 240
 None
 1.04A 5j4nA-2iwzA:
undetectable		 5j4nA-2iwzA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6

(Homo sapiens) 		PF01852
(START) 		4 SER A 100
GLY A 146
ASN A 148
ILE A  97
 None
 1.00A 5j4nA-2mouA:
undetectable		 5j4nA-2mouA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1b AMINOTRANSFERASE,
CLASS I

(Staphylococcus
aureus) 		PF00155
(Aminotran_1_2) 		4 SER A 289
GLY A 204
ASN A 212
ILE A 317
 None
 0.95A 5j4nA-2o1bA:
undetectable		 5j4nA-2o1bA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE

(Helicobacter
pylori) 		PF00483
(NTP_transferase) 		4 SER A 243
GLY A 187
ASN A 185
ILE A  92
 None
 1.11A 5j4nA-2qh5A:
undetectable		 5j4nA-2qh5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8n LACTOSE PERMEASE

(Escherichia
coli) 		PF01306
(LacY_symp) 		4 SER A  41
GLY A 370
ASN A 371
ILE A  48
 None
 0.94A 5j4nA-2v8nA:
undetectable		 5j4nA-2v8nA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN

(Neisseria
meningitidis) 		PF13429
(TPR_15) 		4 SER A 124
GLY A 116
ASN A 119
ILE A 149
 None
 1.11A 5j4nA-2vq2A:
undetectable		 5j4nA-2vq2A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wok CLAVULANIC ACID
BIOSYNTHESIS
OLIGOPEPTIDE BINDING
PROTEIN 2

(Streptomyces
clavuligerus) 		PF00496
(SBP_bac_5) 		4 SER A 181
GLY A 462
ILE A 494
TRP A 510
 None
 1.05A 5j4nA-2wokA:
undetectable		 5j4nA-2wokA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsm HYDROGENASE
EXPRESSION/FORMATION
PROTEIN (HYPB)

(Archaeoglobus
fulgidus) 		PF02492
(cobW) 		4 GLY A  42
ASN A 162
MET A 136
ILE A  47
 None
 1.13A 5j4nA-2wsmA:
undetectable		 5j4nA-2wsmA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhl GALECTIN-9

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 SER A  54
GLY A  80
ASN A  79
ILE A  58
 None
 1.14A 5j4nA-2zhlA:
undetectable		 5j4nA-2zhlA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zy2 L-ASPARTATE
4-CARBOXYLYASE

(Pseudomonas sp.
ATCC 19121) 		PF00155
(Aminotran_1_2) 		4 SER A 397
GLY A 325
MET A 393
ILE A 152
 None
 1.07A 5j4nA-2zy2A:
undetectable		 5j4nA-2zy2A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE

(Arthrobacter
sp. KI72) 		PF01425
(Amidase) 		4 SER A  93
GLY A 328
ASN A 327
MET A  90
 None
 1.08A 5j4nA-3a2qA:
undetectable		 5j4nA-3a2qA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aar ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE I

(Legionella
pneumophila) 		PF01150
(GDA1_CD39) 		4 SER A 355
GLY A 259
ASN A 260
ILE A 329
 None
 0.93A 5j4nA-3aarA:
undetectable		 5j4nA-3aarA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agr NUCLEOSIDE
TRIPHOSPHATE
HYDROLASE

(Neospora
caninum) 		PF01150
(GDA1_CD39) 		4 SER A 309
GLY A 344
ASN A 363
ILE A 412
 None
 1.11A 5j4nA-3agrA:
undetectable		 5j4nA-3agrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3awd PUTATIVE POLYOL
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF13561
(adh_short_C2) 		4 SER A 165
GLY A 122
ASN A 121
ILE A  97
 None
 1.16A 5j4nA-3awdA:
undetectable		 5j4nA-3awdA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN

(Thermotoga
maritima) 		no annotation 4 SER B 138
GLY B 188
ASN B 193
ILE B 159
 None
 1.15A 5j4nA-3c6qB:
undetectable		 5j4nA-3c6qB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3u 4-HYDROXYBUTYRATE
COA-TRANSFERASE

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 SER A 125
GLY A 131
ASN A 128
ILE A 169
 None
 1.12A 5j4nA-3d3uA:
undetectable		 5j4nA-3d3uA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fij LIN1909 PROTEIN

(Listeria
innocua) 		PF07722
(Peptidase_C26) 		4 SER A 229
ASN A 175
MET A 222
TRP A 217
 None
 1.11A 5j4nA-3fijA:
undetectable		 5j4nA-3fijA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fij LIN1909 PROTEIN

(Listeria
innocua) 		PF07722
(Peptidase_C26) 		4 SER A 229
GLY A 152
ASN A 175
MET A 222
 None
 1.01A 5j4nA-3fijA:
undetectable		 5j4nA-3fijA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbu SECRETED PROTEASE C

(Dickeya
chrysanthemi) 		PF00353
(HemolysinCabind)
PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		4 SER P 321
GLY P 354
ASN P 355
ILE P 315
 None
CA  P 483 ( 4.7A)
None
None
 0.84A 5j4nA-3hbuP:
undetectable		 5j4nA-3hbuP:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE SMALL
FES SUBUNIT

(Eubacterium
barkeri) 		PF00111
(Fer2)
PF01799
(Fer2_2) 		4 SER D  37
GLY D  79
ASN D  11
ILE D 109
 None
 1.07A 5j4nA-3hrdD:
undetectable		 5j4nA-3hrdD:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ide CAPSID PROTEIN VP2

(Infectious
pancreatic
necrosis virus) 		PF01766
(Birna_VP2) 		4 SER A 129
GLY A 341
ASN A 342
ILE A 232
 None
 0.74A 5j4nA-3ideA:
undetectable		 5j4nA-3ideA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixc HEXAPEPTIDE
TRANSFERASE FAMILY
PROTEIN

(Anaplasma
phagocytophilum) 		PF00132
(Hexapep) 		4 SER A 166
GLY A  57
ASN A  36
ILE A  39
 None
 1.06A 5j4nA-3ixcA:
undetectable		 5j4nA-3ixcA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3krn PROTEIN C14A4.5,
CONFIRMED BY
TRANSCRIPT EVIDENCE

(Caenorhabditis
elegans) 		PF01138
(RNase_PH) 		4 SER A 193
GLY A 129
ASN A 110
ILE A 132
 None
 1.16A 5j4nA-3krnA:
undetectable		 5j4nA-3krnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kuz PLEXIN-C1

(Homo sapiens) 		PF08337
(Plexin_cytopl) 		4 SER A1221
GLY A1297
ASN A1296
ILE A1300
 None
 1.12A 5j4nA-3kuzA:
undetectable		 5j4nA-3kuzA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwb D-ALANINE--D-ALANINE
LIGASE

(Mycobacterium
tuberculosis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 SER A 253
GLY A 256
MET A 346
ILE A 298
 None
 0.85A 5j4nA-3lwbA:
undetectable		 5j4nA-3lwbA:
23.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ncy ADIC

(Salmonella
enterica) 		PF13520
(AA_permease_2) 		5 GLY A 100
ASN A 101
MET A 104
ILE A 205
TRP A 293
 None
 0.70A 5j4nA-3ncyA:
56.6		 5j4nA-3ncyA:
94.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nz3 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
pneumoniae) 		no annotation 4 GLY A  60
ASN A  61
ILE A  14
TRP A  62
 None
 1.03A 5j4nA-3nz3A:
undetectable		 5j4nA-3nz3A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		4 SER A 659
GLY A 632
ASN A 631
ILE A 598
 None
 0.96A 5j4nA-3o8oA:
undetectable		 5j4nA-3o8oA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 SER A 664
GLY A 607
ASN A 669
ILE A 695
 None
 1.11A 5j4nA-3opyA:
undetectable		 5j4nA-3opyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 SER A 664
GLY A 637
ASN A 636
ILE A 603
 None
None
SO4  A 992 ( 4.0A)
None
 1.16A 5j4nA-3opyA:
undetectable		 5j4nA-3opyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 SER B 637
GLY B 610
ASN B 609
ILE B 576
 None
 1.07A 5j4nA-3opyB:
undetectable		 5j4nA-3opyB:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pic CIP2

(Trichoderma
reesei) 		no annotation 4 SER A 313
GLY A 306
ILE A 329
TRP A 310
 None
 1.12A 5j4nA-3picA:
undetectable		 5j4nA-3picA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni) 		PF00709
(Adenylsucc_synt) 		4 SER A 324
GLY A  16
MET A 326
ILE A   7
 None
 0.97A 5j4nA-3r7tA:
undetectable		 5j4nA-3r7tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4x OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Bacillus
anthracis) 		PF00106
(adh_short) 		4 SER A 116
GLY A  14
ASN A  37
ILE A  92
 None
 1.14A 5j4nA-3t4xA:
undetectable		 5j4nA-3t4xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 SER A 245
GLY A 270
MET A 274
ILE A 214
 None
 1.01A 5j4nA-3t6qA:
undetectable		 5j4nA-3t6qA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfo PUTATIVE
3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		4 SER A 164
GLY A 139
ASN A 180
ILE A 136
 None
 1.14A 5j4nA-3tfoA:
undetectable		 5j4nA-3tfoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii) 		PF00398
(RrnaAD) 		4 SER A 112
GLY A 105
ASN A 106
ILE A 185
 None
 1.09A 5j4nA-3tqsA:
undetectable		 5j4nA-3tqsA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u97 RIBONUCLEASE TOXIN
BRNT

(Brucella
abortus) 		PF04365
(BrnT_toxin) 		4 SER A  31
GLY A  50
ASN A  49
ILE A  53
 None
 1.06A 5j4nA-3u97A:
undetectable		 5j4nA-3u97A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3voc BETA/ALPHA-AMYLASE

(Paenibacillus
polymyxa) 		PF01373
(Glyco_hydro_14) 		4 SER A   9
GLY A 358
ASN A 357
ILE A 410
 None
 1.07A 5j4nA-3vocA:
undetectable		 5j4nA-3vocA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsk PENICILLIN-BINDING
PROTEIN 3

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 GLY A 367
ASN A 349
MET A 351
ILE A 381
 None
 1.16A 5j4nA-3vskA:
undetectable		 5j4nA-3vskA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vw7 PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 SER A 360
GLY A 327
ASN A 330
ILE A 321
 None
OLC  A2007 (-3.6A)
None
None
 1.14A 5j4nA-3vw7A:
undetectable		 5j4nA-3vw7A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vx6 E1

(Kluyveromyces
marxianus) 		PF16420
(ATG7_N) 		4 SER A 219
GLY A 248
ASN A 249
ILE A 244
 None
 1.02A 5j4nA-3vx6A:
undetectable		 5j4nA-3vx6A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 SER A  73
GLY A  53
ASN A 150
ILE A 349
 None
FES  A3002 (-3.9A)
None
FAD  A3005 ( 4.3A)
 1.08A 5j4nA-3zyvA:
undetectable		 5j4nA-3zyvA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aut DECAPRENYL-PHOSPHORY
L-BETA-D-RIBOFURANOS
E-2-OXIDOREDUCTASE

(Mycolicibacterium
smegmatis) 		PF01565
(FAD_binding_4)
PF04030
(ALO) 		4 SER A 385
GLY A 150
ASN A 151
ILE A 138
 None
None
None
FAD  A 600 (-3.7A)
 1.02A 5j4nA-4autA:
undetectable		 5j4nA-4autA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ezd UREA TRANSPORTER 1

(Bos taurus) 		PF03253
(UT) 		4 SER A 248
GLY A 294
ASN A 368
ILE A 290
 None
 1.08A 5j4nA-4ezdA:
undetectable		 5j4nA-4ezdA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdg MINICHROMOSOME
MAINTENANCE PROTEIN
MCM

(Sulfolobus
solfataricus) 		no annotation 4 SER B 347
GLY B 447
ASN B 448
ILE B 403
 None
 0.91A 5j4nA-4fdgB:
undetectable		 5j4nA-4fdgB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3t OXIDOREDUCTASE DPRE1

(Mycolicibacterium
smegmatis) 		PF01565
(FAD_binding_4)
PF04030
(ALO) 		4 SER A 385
GLY A 150
ASN A 151
ILE A 138
 None
 1.05A 5j4nA-4g3tA:
undetectable		 5j4nA-4g3tA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4i 4-O-METHYL-GLUCURONO
YL METHYLESTERASE

(Thermothelomyces
thermophila) 		no annotation 4 SER A 248
GLY A 241
ILE A 264
TRP A 245
 None
 1.08A 5j4nA-4g4iA:
undetectable		 5j4nA-4g4iA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9b BETA-PHOSPHOGLUCOMUT
ASE

(Escherichia
coli) 		PF13419
(HAD_2) 		4 SER A 183
GLY A 169
MET A 185
ILE A 152
 None
 0.95A 5j4nA-4g9bA:
undetectable		 5j4nA-4g9bA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hem BPP

(Lactococcus
phage TP901-1) 		PF08931
(Caudo_bapla_RBP) 		4 SER A 102
GLY A  73
ILE A 134
TRP A 144
 None
 1.14A 5j4nA-4hemA:
undetectable		 5j4nA-4hemA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ic6 PROTEASE DO-LIKE 8,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 SER A 327
GLY A 280
ASN A 266
ILE A 304
 None
 1.04A 5j4nA-4ic6A:
undetectable		 5j4nA-4ic6A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jjn HISTONE H2A.2
HISTONE H2B.2

(Saccharomyces
cerevisiae) 		PF00125
(Histone)
PF16211
(Histone_H2A_C) 		4 SER D  81
GLY C  38
ASN C  39
ILE C  44
 None
 1.13A 5j4nA-4jjnD:
undetectable		 5j4nA-4jjnD:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3x HEMAGGLUTININ HA1
HEMAGGLUTININ HA2

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 GLY B 136
ASN B 135
MET B 133
ILE A  13
 None
 1.03A 5j4nA-4k3xB:
undetectable		 5j4nA-4k3xB:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh9 HYPOTHETICAL PROTEIN

(Legionella
pneumophila) 		PF16024
(DUF4785) 		4 SER A 285
GLY A 373
ASN A 250
ILE A 370
 None
 1.13A 5j4nA-4kh9A:
undetectable		 5j4nA-4kh9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kw5 OXIDOREDUCTASE

(Mycobacterium
tuberculosis) 		PF01565
(FAD_binding_4)
PF04030
(ALO) 		4 SER A 378
GLY A 143
ASN A 144
ILE A 131
 None
None
None
FAD  A 501 (-3.7A)
 1.02A 5j4nA-4kw5A:
undetectable		 5j4nA-4kw5A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B

(Lactobacillus
rhamnosus) 		PF02502
(LacAB_rpiB) 		4 SER B  19
GLY B   6
ASN B   7
ILE B  30
 None
 1.05A 5j4nA-4lfnB:
undetectable		 5j4nA-4lfnB:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mc5 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 GLY A 465
ASN A 464
MET A 462
ILE A   7
 None
 0.99A 5j4nA-4mc5A:
undetectable		 5j4nA-4mc5A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0r PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
vulgatus) 		PF13204
(DUF4038)
PF16586
(DUF5060) 		4 SER A 442
GLY A 380
ASN A 379
ILE A 423
 None
 0.91A 5j4nA-4n0rA:
undetectable		 5j4nA-4n0rA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oou BETA-1,4-MANNANASE

(Cryptopygus
antarcticus) 		no annotation 4 SER B  75
GLY B  41
MET B 360
ILE B  69
 None
 1.11A 5j4nA-4oouB:
undetectable		 5j4nA-4oouB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q68 UNCHARACTERIZED
PROTEIN

(Bacteroides
uniformis) 		PF07313
(DUF1460) 		4 GLY A 120
ASN A 119
ILE A 198
TRP A 116
 None
 1.03A 5j4nA-4q68A:
undetectable		 5j4nA-4q68A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7w SERRALYSIN

(Serratia
marcescens) 		PF00353
(HemolysinCabind)
PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		4 SER A 309
GLY A 342
ASN A 343
ILE A 303
 SER  A 309 ( 0.0A)
GLY  A 342 ( 0.0A)
ASN  A 343 (-0.6A)
ILE  A 303 ( 0.7A)
 0.86A 5j4nA-5d7wA:
undetectable		 5j4nA-5d7wA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e31 PENICILLIN BINDING
PROTEIN 2 PRIME

(Enterococcus
faecium) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF05223
(MecA_N) 		4 SER A 365
GLY A 417
ASN A 546
ILE A 411
 None
 1.05A 5j4nA-5e31A:
undetectable		 5j4nA-5e31A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ee4 HPUA

(Kingella
denitrificans) 		PF16960
(HpuA) 		4 SER A 210
GLY A 227
ASN A 228
ILE A 235
 None
 1.14A 5j4nA-5ee4A:
undetectable		 5j4nA-5ee4A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey5 LBCA-B
LBCATS-A

(synthetic
construct) 		PF00290
(Trp_syntA)
PF00291
(PALP) 		4 SER A  55
GLY B 289
ASN A 104
ILE B 292
 None
 1.07A 5j4nA-5ey5A:
undetectable		 5j4nA-5ey5A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i20 UNCHARACTERIZED
PROTEIN

(Starkeya
novella) 		PF00892
(EamA) 		4 SER A 170
GLY A 231
ILE A 105
TRP A 228
 None
 1.14A 5j4nA-5i20A:
undetectable		 5j4nA-5i20A:
26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k82 APOLIPOPROTEIN B
MRNA EDITING ENZYME,
CATALYTIC
PEPTIDE-LIKE
3G,APOLIPOPROTEIN B
MRNA EDITING ENZYME,
CATALYTIC
PEPTIDE-LIKE 3G

(Macaca mulatta) 		PF08210
(APOBEC_N) 		4 SER A  93
GLY A  56
ILE A  53
TRP A  34
 None
 1.12A 5j4nA-5k82A:
undetectable		 5j4nA-5k82A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kod INDOLE-3-ACETIC
ACID-AMIDO
SYNTHETASE GH3.5

(Arabidopsis
thaliana) 		PF03321
(GH3) 		4 SER A 365
GLY A 346
MET A 366
ILE A  28
 None
 1.08A 5j4nA-5kodA:
undetectable		 5j4nA-5kodA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 GLY A 104
ASN A 103
MET A 100
ILE A 107
 None
NAG  A 608 (-1.9A)
NAG  A 605 ( 3.9A)
None
 1.03A 5j4nA-5lm8A:
undetectable		 5j4nA-5lm8A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n86 STABILIN-2

(Homo sapiens) 		no annotation 4 SER A   1
GLY A 127
ASN A 126
ILE A 122
 None
 1.16A 5j4nA-5n86A:
undetectable		 5j4nA-5n86A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocp -

(-) 		no annotation 4 GLY A 146
ASN A 148
ILE A 114
TRP A 192
 None
 1.11A 5j4nA-5ocpA:
undetectable		 5j4nA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovy PUTATIVE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Mycobacteroides
abscessus) 		no annotation 4 GLY B  91
ASN B  87
ILE B 186
TRP B  89
 None
 1.16A 5j4nA-5ovyB:
undetectable		 5j4nA-5ovyB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szs SPIKE GLYCOPROTEIN

(Human
coronavirus
NL63) 		PF01600
(Corona_S1)
PF01601
(Corona_S2) 		4 SER A 772
GLY A1110
ASN A1111
ILE A1115
 None
None
NAG  A1464 ( 1.8A)
None
 1.13A 5j4nA-5szsA:
undetectable		 5j4nA-5szsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tfm CADHERIN-23

(Homo sapiens) 		no annotation 4 SER A 581
GLY A 612
ASN A 611
ILE A 636
 None
 0.97A 5j4nA-5tfmA:
undetectable		 5j4nA-5tfmA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8k P800 REACTION CENTER
CORE PROTEIN

(Heliobacterium
modesticaldum) 		PF00223
(PsaA_PsaB) 		4 SER A 545
GLY A 590
MET A 546
ILE A 539
 AOH  A1003 (-4.3A)
None
None
GBF  A1002 ( 4.4A)
 1.15A 5j4nA-5v8kA:
undetectable		 5j4nA-5v8kA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 SER B  63
GLY B  13
ASN B  14
ILE B 135
 None
 1.04A 5j4nA-5w3jB:
undetectable		 5j4nA-5w3jB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xex POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Staphylococcus
aureus) 		no annotation 4 SER A 125
GLY A 151
MET A 128
ILE A 163
 None
 1.15A 5j4nA-5xexA:
undetectable		 5j4nA-5xexA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu6 INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Cryptococcus
neoformans) 		PF06090
(Ins_P5_2-kin) 		4 SER A 226
GLY A 214
ILE A 152
TRP A 229
 None
 0.92A 5j4nA-5xu6A:
undetectable		 5j4nA-5xu6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6at7 PHENYLALANINE
AMMONIA-LYASE

(Sorghum bicolor) 		no annotation 4 SER A 159
GLY A 248
ASN A 369
ILE A 245
 None
MDO  A 190 ( 4.0A)
None
None
 1.12A 5j4nA-6at7A:
undetectable		 5j4nA-6at7A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fai SERINE/THREONINE-PRO
TEIN KINASE RIO2

(Saccharomyces
cerevisiae) 		no annotation 4 SER l  41
GLY l  48
MET l  43
ILE l  53
 None
 1.16A 5j4nA-6fail:
undetectable		 5j4nA-6fail:
10.86