SIMILAR PATTERNS OF AMINO ACIDS FOR 5IWU_A_ERYA404_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b74 | GLUTAMATE RACEMASE (Aquifexpyrophilus) |
PF01177(Asp_Glu_race) | 5 | ILE A 175TYR A 123THR A 14ALA A 122SER A 207 | None | 1.09A | 5iwuA-1b74A:undetectable | 5iwuA-1b74A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | ILE A 233HIS A 232TYR A 234ALA A 332ILE A 343 | None | 1.42A | 5iwuA-1ebvA:undetectable | 5iwuA-1ebvA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gzv | GLUCOSE-6-PHOSPHATEISOMERASE (Sus scrofa) |
PF00342(PGI) | 5 | THR A 167PHE A 205ALA A 224SER A 159ILE A 156 | NoneNoneNonePA5 A 600 (-3.4A)None | 1.35A | 5iwuA-1gzvA:0.0 | 5iwuA-1gzvA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jed | SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | ILE A 82THR A 38ALA A 293SER A 143ILE A 142 | NoneNoneADP A 635 (-4.4A)NoneNone | 1.06A | 5iwuA-1jedA:0.0 | 5iwuA-1jedA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofe | FERREDOXIN-DEPENDENTGLUTAMATE SYNTHASE 2 (Synechocystissp. PCC 6803) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | ILE A 965HIS A1006THR A1363ALA A 968ILE A1012 | None | 1.32A | 5iwuA-1ofeA:0.0 | 5iwuA-1ofeA:12.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t90 | PROBABLEMETHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Bacillussubtilis) |
PF00171(Aldedh) | 5 | ILE A 46THR A 185ALA A 54SER A 225ILE A 224 | None | 1.15A | 5iwuA-1t90A:0.0 | 5iwuA-1t90A:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tmo | TRIMETHYLAMINEN-OXIDE REDUCTASE (Shewanellamassilia) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | ILE A 422TYR A 431THR A 155SER A 769ILE A 759 | None | 1.43A | 5iwuA-1tmoA:0.0 | 5iwuA-1tmoA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1to6 | GLYCERATE KINASE (Neisseriameningitidis) |
PF02595(Gly_kinase) | 5 | ILE A 247GLU A 114PHE A 254ALA A 253ILE A 127 | None | 1.31A | 5iwuA-1to6A:0.0 | 5iwuA-1to6A:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1to6 | GLYCERATE KINASE (Neisseriameningitidis) |
PF02595(Gly_kinase) | 5 | THR A 66GLU A 114PHE A 254ALA A 253ILE A 127 | None | 1.44A | 5iwuA-1to6A:0.0 | 5iwuA-1to6A:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbl | PECTATE LYASE 47 (Bacillus sp.TS-47) |
PF00544(Pec_lyase_C) | 5 | THR A 66ALA A 410SER A 191ILE A 192PHE A 150 | None | 1.33A | 5iwuA-1vblA:undetectable | 5iwuA-1vblA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve1 | O-ACETYLSERINESULFHYDRYLASE (Thermusthermophilus) |
PF00291(PALP) | 5 | ILE A 167THR A 10GLU A 31ALA A 275ILE A 180 | None | 1.25A | 5iwuA-1ve1A:undetectable | 5iwuA-1ve1A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wl4 | ACETYL-COENZYME AACETYLTRANSFERASE 2 (Homo sapiens) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ILE A 280THR A 365GLU A 319ALA A 308ILE A 390 | None | 1.41A | 5iwuA-1wl4A:undetectable | 5iwuA-1wl4A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x9s | DNA POLYMERASE (Escherichiavirus T7) |
PF00476(DNA_pol_A) | 5 | ILE A 562GLU A 480PHE A 524ALA A 513ILE A 500 | None | 1.17A | 5iwuA-1x9sA:undetectable | 5iwuA-1x9sA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xx6 | THYMIDINE KINASE (Clostridiumacetobutylicum) |
PF00265(TK) | 5 | ILE A 141GLU A 89ALA A 152ILE A 128MET A 132 | None | 1.41A | 5iwuA-1xx6A:undetectable | 5iwuA-1xx6A:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7a | CONSERVEDHYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF01522(Polysacc_deac_1) | 5 | HIS A 259HIS A 126THR A 168ALA A 106PHE A 53 | None | 1.26A | 5iwuA-1z7aA:undetectable | 5iwuA-1z7aA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4k | PHOSPHORIBOSYLPYROPHOSPHATESYNTHETASE-ASSOCIATED PROTEIN 1 (Homo sapiens) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 5 | ILE A 92THR A 47GLU A 76PHE A 11ILE A 96 | None | 1.42A | 5iwuA-2c4kA:undetectable | 5iwuA-2c4kA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cun | PHOSPHOGLYCERATEKINASE (Pyrococcushorikoshii) |
PF00162(PGK) | 5 | HIS A 72ALA A 148SER A 116ILE A 90PHE A 115 | NoneNoneNoneMPD A 509 (-3.9A)None | 1.16A | 5iwuA-2cunA:undetectable | 5iwuA-2cunA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cxn | GLUCOSE-6-PHOSPHATEISOMERASE (Mus musculus) |
PF00342(PGI) | 5 | THR A 168PHE A 206ALA A 225SER A 160ILE A 157 | NoneNoneNonePO4 A1601 (-2.7A)None | 1.32A | 5iwuA-2cxnA:undetectable | 5iwuA-2cxnA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f3o | PYRUVATEFORMATE-LYASE 2 (Archaeoglobusfulgidus) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | ILE A 314HIS A 265THR A 511GLU A 267ILE A 54 | None | 1.44A | 5iwuA-2f3oA:undetectable | 5iwuA-2f3oA:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g7g | RHA04620, PUTATIVETRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF02909(TetR_C) | 5 | ILE A 132GLU A 72PHE A 80ALA A 139SER A 113 | None | 1.23A | 5iwuA-2g7gA:undetectable | 5iwuA-2g7gA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gfp | MULTIDRUG RESISTANCEPROTEIN D (Escherichiacoli) |
PF07690(MFS_1) | 5 | ILE A 217GLU A 326ALA A 337SER A 207MET A 372 | None | 1.18A | 5iwuA-2gfpA:undetectable | 5iwuA-2gfpA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gx8 | NIF3-RELATED PROTEIN (Bacillus cereus) |
PF01784(NIF3) | 5 | ILE A 99THR A 81GLU A 90ALA A 35ILE A 58 | None | 1.39A | 5iwuA-2gx8A:undetectable | 5iwuA-2gx8A:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h12 | CITRATE SYNTHASE (Acetobacteraceti) |
PF00285(Citrate_synt) | 5 | ILE A 81HIS A 76THR A 243ALA A 88PHE A 392 | NoneNoneNoneNoneCMX A5001 (-4.9A) | 1.39A | 5iwuA-2h12A:undetectable | 5iwuA-2h12A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nwb | CONSERVED DOMAINPROTEIN (Shewanellaoneidensis) |
PF08933(DUF1864) | 5 | ILE A 245TYR A 163GLU A 315ALA A 162PHE A 310 | NoneHEM A 401 ( 4.8A)NoneNoneNone | 1.30A | 5iwuA-2nwbA:undetectable | 5iwuA-2nwbA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1s | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF02779(Transket_pyr)PF02780(Transketolase_C)PF13292(DXP_synthase_N) | 5 | THR A 56ALA A 367SER A 126ILE A 127MET A 164 | None | 1.39A | 5iwuA-2o1sA:undetectable | 5iwuA-2o1sA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2c | GLUCOSE-6-PHOSPHATEISOMERASE,GLYCOSOMAL (Trypanosomabrucei) |
PF00342(PGI) | 5 | THR A 216PHE A 254ALA A 273SER A 208ILE A 205 | NoneNoneNoneG6Q A5001 (-2.7A)None | 1.35A | 5iwuA-2o2cA:undetectable | 5iwuA-2o2cA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odp | COMPLEMENT C2 (Homo sapiens) |
PF00089(Trypsin)PF00092(VWA) | 5 | THR A 640ALA A 475SER A 521ILE A 520PHE A 524 | None | 1.36A | 5iwuA-2odpA:undetectable | 5iwuA-2odpA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3o | 12-OXOPHYTODIENOATEREDUCTASE 3 (Arabidopsisthaliana) |
PF00724(Oxidored_FMN) | 5 | ILE A 185THR A 33PHE A 104ALA A 276SER A 320 | NoneFMN A7401 (-3.8A)NoneNoneFMN A7401 ( 4.2A) | 1.29A | 5iwuA-2q3oA:undetectable | 5iwuA-2q3oA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qt3 | N-ISOPROPYLAMMELIDEISOPROPYLAMIDOHYDROLASE (Pseudomonas sp.ADP) |
PF01979(Amidohydro_1) | 5 | GLU A 197PHE A 163ALA A 159SER A 228ILE A 229 | None | 1.25A | 5iwuA-2qt3A:undetectable | 5iwuA-2qt3A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qt3 | N-ISOPROPYLAMMELIDEISOPROPYLAMIDOHYDROLASE (Pseudomonas sp.ADP) |
PF01979(Amidohydro_1) | 5 | ILE A 214GLU A 197PHE A 163ALA A 159ILE A 229 | None | 1.35A | 5iwuA-2qt3A:undetectable | 5iwuA-2qt3A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9h | H(+)/CL(-) EXCHANGETRANSPORTER CLCA (Escherichiacoli) |
PF00654(Voltage_CLC) | 5 | ILE A 410THR A 226ALA A 404ILE A 215PHE A 219 | None | 1.13A | 5iwuA-2r9hA:undetectable | 5iwuA-2r9hA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF13416(SBP_bac_8) | 5 | HIS A 395THR A 149SER A 303ILE A 302PHE A 155 | NoneNoneNoneNoneGAL A1429 ( 4.5A) | 1.43A | 5iwuA-2w7yA:undetectable | 5iwuA-2w7yA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww2 | ALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 5 | HIS A 89PHE A 61ALA A 54SER A 102ILE A 103 | None | 1.40A | 5iwuA-2ww2A:undetectable | 5iwuA-2ww2A:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 5 | HIS A 83PHE A 55ALA A 48SER A 96ILE A 97 | None | 1.42A | 5iwuA-2wzsA:1.1 | 5iwuA-2wzsA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yg6 | PUTRESCINE OXIDASE (Rhodococcuserythropolis) |
PF01593(Amino_oxidase) | 5 | ILE A 272ALA A 36SER A 421ILE A 261PHE A 420 | NoneFAD A 600 (-3.5A)NoneNoneNone | 1.36A | 5iwuA-2yg6A:undetectable | 5iwuA-2yg6A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yky | BETA-TRANSAMINASE (Mesorhizobiumsp. LUK) |
PF00202(Aminotran_3) | 5 | ILE A 217THR A 257GLU A 254ALA A 156SER A 135 | None | 1.15A | 5iwuA-2ykyA:undetectable | 5iwuA-2ykyA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | ILE A 620HIS A 435PHE A 516ALA A 614MET A 350 | None | 1.24A | 5iwuA-2zxqA:0.5 | 5iwuA-2zxqA:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a2f | DNA POLYMERASE (Pyrococcusfuriosus) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | ILE A 663TYR A 702GLU A 735ALA A 715ILE A 656 | None | 1.43A | 5iwuA-3a2fA:undetectable | 5iwuA-3a2fA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b57 | LIN1889 PROTEIN (Listeriainnocua) |
PF01966(HD) | 5 | ILE A 85THR A 113GLU A 115PHE A 57ALA A 10 | None | 1.37A | 5iwuA-3b57A:undetectable | 5iwuA-3b57A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cl6 | PUUE ALLANTOINASE (Pseudomonasfluorescens) |
PF01522(Polysacc_deac_1) | 5 | HIS A 259HIS A 126THR A 168ALA A 106PHE A 53 | None | 1.22A | 5iwuA-3cl6A:undetectable | 5iwuA-3cl6A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cq5 | HISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Corynebacteriumglutamicum) |
PF00155(Aminotran_1_2) | 5 | ILE A 247THR A 210PHE A 109ALA A 108SER A 98 | NoneNoneNoneNonePMP A 401 (-3.3A) | 1.31A | 5iwuA-3cq5A:undetectable | 5iwuA-3cq5A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dh4 | SODIUM/GLUCOSECOTRANSPORTER (Vibrioparahaemolyticus) |
PF00474(SSF) | 5 | ILE A 97THR A 514ALA A 528ILE A 271PHE A 106 | None | 1.37A | 5iwuA-3dh4A:undetectable | 5iwuA-3dh4A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjb | GLUCOSE-6-PHOSPHATEISOMERASE (Vibrio cholerae) |
PF00342(PGI) | 5 | THR A 167PHE A 204ALA A 223SER A 159ILE A 156 | None | 1.35A | 5iwuA-3hjbA:undetectable | 5iwuA-3hjbA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjw | PSEUDOURIDINESYNTHASE CBF5 (Pyrococcusfuriosus) |
PF01472(PUA)PF01509(TruB_N)PF08068(DKCLD)PF16198(TruB_C_2) | 5 | ILE A 187GLU A 162PHE A 135ALA A 193ILE A 166 | None | 1.34A | 5iwuA-3hjwA:undetectable | 5iwuA-3hjwA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3my9 | MUCONATECYCLOISOMERASE (Azorhizobiumcaulinodans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 209HIS A 173PHE A 236PHE A 216MET A 166 | None | 1.36A | 5iwuA-3my9A:undetectable | 5iwuA-3my9A:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nbu | GLUCOSE-6-PHOSPHATEISOMERASE (Escherichiacoli) |
PF00342(PGI) | 5 | THR A 166PHE A 203ALA A 222SER A 158ILE A 155 | None | 1.26A | 5iwuA-3nbuA:undetectable | 5iwuA-3nbuA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6b | DEFECTIVE IN CULLINNEDDYLATION PROTEIN1CELL DIVISIONCONTROL PROTEIN 53 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF03556(Cullin_binding)PF10557(Cullin_Nedd8) | 5 | ILE B 793TYR B 811HIS B 767GLU A 250ILE A 257 | None | 0.98A | 5iwuA-3o6bB:undetectable | 5iwuA-3o6bB:13.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3prl | NADP-DEPENDENTGLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Bacillushalodurans) |
PF00171(Aldedh) | 5 | ILE A 117THR A 238ALA A 124ILE A 212PHE A 185 | None | 1.40A | 5iwuA-3prlA:undetectable | 5iwuA-3prlA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgu | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Chlamydomonasreinhardtii) |
PF00155(Aminotran_1_2) | 5 | ILE A 244THR A 263GLU A 276ALA A 159SER A 141 | NoneNoneNoneNoneSO4 A 451 (-4.8A) | 1.44A | 5iwuA-3qguA:undetectable | 5iwuA-3qguA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thw | DNA MISMATCH REPAIRPROTEIN MSH3 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05192(MutS_III) | 5 | ILE B 666HIS B 818ALA B 820SER B 656ILE B 654 | None | 1.13A | 5iwuA-3thwB:undetectable | 5iwuA-3thwB:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tzw | POLYKETIDE SYNTHASEPKS13 (Mycobacteriumtuberculosis) |
PF00698(Acyl_transf_1) | 5 | ILE A1041TYR A1033HIS A 670ALA A 675ILE A 661 | None | 1.41A | 5iwuA-3tzwA:undetectable | 5iwuA-3tzwA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrf | NON-REDUCING ENDBETA-L-ARABINOFURANOSIDASE (Bifidobacteriumlongum) |
PF07944(Glyco_hydro_127) | 5 | ILE A 138TYR A 231GLU A 196ALA A 257SER A 217 | None | 1.39A | 5iwuA-3wrfA:undetectable | 5iwuA-3wrfA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x3y | PHENYLETHYLAMINEOXIDASE (Arthrobacterglobiformis) |
PF01179(Cu_amine_oxid)PF02728(Cu_amine_oxidN3) | 5 | THR A 377PHE A 297ALA A 534SER A 276PHE A 398 | None | 1.42A | 5iwuA-3x3yA:3.4 | 5iwuA-3x3yA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bg2 | PATF (Prochlorondidemni) |
no annotation | 5 | HIS A 140GLU A 180ALA A 108SER A 236PHE A 234 | None | 1.34A | 5iwuA-4bg2A:undetectable | 5iwuA-4bg2A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ff5 | GLYCOSYL HYDROLASE25 (Streptococcuspneumoniae) |
PF01183(Glyco_hydro_25) | 5 | ILE A 77HIS A 60GLU A 108PHE A 116ALA A 120 | None | 1.43A | 5iwuA-4ff5A:undetectable | 5iwuA-4ff5A:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwb | HALOALKANEDEHALOGENASE (Rhodococcusrhodochrous) |
PF00561(Abhydrolase_1) | 5 | HIS A 272GLU A 276PHE A 245ALA A 145ILE A 169 | CL A2003 ( 3.7A)None CL A2003 ( 4.7A)NoneNone | 1.31A | 5iwuA-4fwbA:undetectable | 5iwuA-4fwbA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc3 | INTERLEUKIN-33INTERLEUKIN-1RECEPTOR-LIKE 1 (Homo sapiens;Homo sapiens) |
PF15095(IL33)PF07679(I-set) | 5 | ILE B 214HIS B 314PHE B 239ALA B 248SER A 170 | None | 1.28A | 5iwuA-4kc3B:undetectable | 5iwuA-4kc3B:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l95 | GAMMA-GLUTAMYLHYDROLASE (Danio rerio) |
no annotation | 5 | ILE E 238THR E 227GLU E 285PHE E 37ALA E 245 | None | 1.41A | 5iwuA-4l95E:undetectable | 5iwuA-4l95E:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lyp | EXO-BETA-1,4-MANNOSIDASE (Rhizomucormiehei) |
no annotation | 5 | TYR A 156THR A 253PHE A 116ALA A 152ILE A 173 | None | 1.32A | 5iwuA-4lypA:undetectable | 5iwuA-4lypA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m64 | MELIBIOSE CARRIERPROTEIN (Salmonellaenterica) |
PF13347(MFS_2) | 5 | ILE A 415THR A 425ALA A 254SER A 380PHE A 386 | None | 1.23A | 5iwuA-4m64A:undetectable | 5iwuA-4m64A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mll | BETA-LACTAMASE OXA-1 (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | ILE A 167TYR A 141THR A 219ALA A 72SER A 258 | NoneNoneNoneNone1S6 A 301 (-2.4A) | 1.16A | 5iwuA-4mllA:undetectable | 5iwuA-4mllA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mll | BETA-LACTAMASE OXA-1 (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | TYR A 141THR A 219PHE A 69ALA A 72SER A 258 | NoneNoneNoneNone1S6 A 301 (-2.4A) | 0.94A | 5iwuA-4mllA:undetectable | 5iwuA-4mllA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nwz | FAD-DEPENDENTPYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE (Caldalkalibacillusthermarum) |
PF07992(Pyr_redox_2) | 5 | ILE A 387TYR A 383HIS A 42ALA A 316ILE A 8 | NoneNoneNoneFAD A 601 (-3.6A)None | 1.26A | 5iwuA-4nwzA:undetectable | 5iwuA-4nwzA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6d | NS1 (West Nile virus) |
PF00948(Flavi_NS1) | 5 | ILE B 275TYR B 323GLU B 219ALA B 297SER B 222 | None | 1.36A | 5iwuA-4o6dB:undetectable | 5iwuA-4o6dB:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4omg | GERANYLGERANYLDIPHOSPHATE CYCLASE (Streptomycesmelanosporofaciens) |
no annotation | 5 | THR A 47GLU A 50ALA A 60PHE A 96MET A 189 | None | 1.44A | 5iwuA-4omgA:undetectable | 5iwuA-4omgA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opu | CONSERVED ARCHAEALPROTEIN (Sulfolobusacidocaldarius) |
PF01266(DAO) | 5 | ILE A 10THR A 292PHE A 163ALA A 122ILE A 42 | NoneNoneNoneFDA A 501 (-4.0A)None | 1.44A | 5iwuA-4opuA:undetectable | 5iwuA-4opuA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqz | PUTATIVEOXIDOREDUCTASE YFJR (Streptomycesaurantiacus) |
PF03446(NAD_binding_2) | 5 | TYR A 69HIS A 113ALA A 166ILE A 151MET A 17 | None | 1.36A | 5iwuA-4oqzA:undetectable | 5iwuA-4oqzA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj3 | INTRON-BINDINGPROTEIN AQUARIUS (Homo sapiens) |
PF13086(AAA_11)PF13087(AAA_12)PF16399(Aquarius_N) | 5 | THR A1229ALA A1139SER A1225ILE A1224MET A1214 | None | 1.35A | 5iwuA-4pj3A:undetectable | 5iwuA-4pj3A:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1y | ATRAZINECHLOROHYDROLASE (Pseudomonas sp.ADP) |
PF01979(Amidohydro_1) | 5 | TYR A 111THR A 241ALA A 115SER A 210ILE A 209 | None | 1.17A | 5iwuA-4v1yA:undetectable | 5iwuA-4v1yA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v39 | SIALYLTRANSFERASE (Pasteurelladagmatis) |
PF11477(PM0188) | 5 | ILE A 150TYR A 144HIS A 91GLU A 62PHE A 90 | None | 1.36A | 5iwuA-4v39A:undetectable | 5iwuA-4v39A:24.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wmj | GLUCOSE-6-PHOSPHATEISOMERASE (Coliaseurytheme) |
PF00342(PGI) | 5 | THR A 172PHE A 209ALA A 228SER A 164ILE A 161 | None | 1.34A | 5iwuA-4wmjA:undetectable | 5iwuA-4wmjA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wso | PROBABLENICOTINATE-NUCLEOTIDEADENYLYLTRANSFERASE (Burkholderiathailandensis) |
PF01467(CTP_transf_like) | 5 | ILE A 135THR A 202ALA A 156ILE A 179PHE A 168 | NAD A 301 (-4.1A)NoneNoneNoneNone | 1.38A | 5iwuA-4wsoA:undetectable | 5iwuA-4wsoA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxx | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 5 | ILE A1314PHE A1263ALA A1317SER A1161ILE A1160 | None | 1.36A | 5iwuA-4wxxA:undetectable | 5iwuA-4wxxA:12.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ygu | PUTATIVE ADHESIN (Bacteroideseggerthii) |
PF10988(DUF2807) | 5 | ILE A 49GLU A 112PHE A 38ALA A 105SER A 131 | None | 1.32A | 5iwuA-4yguA:undetectable | 5iwuA-4yguA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yue | S4B6 FAB HEAVY CHAINS4B6 FAB LIGHT CHAIN (Mus musculus;Mus musculus) |
PF07654(C1-set)PF07686(V-set)PF07654(C1-set)PF07686(V-set) | 5 | TYR L 99HIS L 94THR L 55PHE H 113SER H 107 | None | 1.37A | 5iwuA-4yueL:undetectable | 5iwuA-4yueL:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b2d | HN PROTEIN (Mumpsrubulavirus) |
PF00423(HN) | 5 | ILE A 387THR A 295GLU A 393PHE A 320ALA A 247 | None | 1.13A | 5iwuA-5b2dA:0.6 | 5iwuA-5b2dA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bnn | CAPSID PROTEIN VP2 (Enterovirus D) |
PF00073(Rhv) | 5 | ILE B 108GLU B 150PHE B 63SER B 68ILE B 228 | None | 1.22A | 5iwuA-5bnnB:undetectable | 5iwuA-5bnnB:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1b | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Homo sapiens) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2)PF09336(Vps4_C) | 5 | ILE A 371HIS A 404ALA A 374SER A 541ILE A 540 | None | 1.44A | 5iwuA-5c1bA:undetectable | 5iwuA-5c1bA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9l | PLL LECTIN (Photorhabdusluminescens) |
PF03984(DUF346) | 5 | ILE A 265PHE A 234ALA A 271SER A 171ILE A 22 | None | 1.36A | 5iwuA-5c9lA:4.0 | 5iwuA-5c9lA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gut | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH) | 5 | ILE A1317PHE A1266ALA A1320SER A1164ILE A1163 | None | 1.44A | 5iwuA-5gutA:undetectable | 5iwuA-5gutA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2v | IMPORTIN SUBUNITBETA-3 (Saccharomycescerevisiae) |
PF13513(HEAT_EZ) | 5 | GLU A 396ALA A 473SER A 440ILE A 443PHE A 439 | None | 1.17A | 5iwuA-5h2vA:undetectable | 5iwuA-5h2vA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hab | RIBONUCLEASE J (Methanolobuspsychrophilus) |
PF07521(RMMBL)PF12706(Lactamase_B_2) | 5 | ILE A 154HIS A 82THR A 208GLU A 206ALA A 104 | NoneNone A C 1 ( 4.4A)NoneNone | 1.19A | 5iwuA-5habA:undetectable | 5iwuA-5habA:23.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5igu | MACROLIDE2'-PHOSPHOTRANSFERASE II (Escherichiacoli) |
PF01636(APH) | 5 | HIS A 202PHE A 234ALA A 238ILE A 277PHE A 280 | None | 1.29A | 5iwuA-5iguA:31.5 | 5iwuA-5iguA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5igu | MACROLIDE2'-PHOSPHOTRANSFERASE II (Escherichiacoli) |
PF01636(APH) | 5 | HIS A 202THR A 221GLU A 222PHE A 234ALA A 238 | None | 1.08A | 5iwuA-5iguA:31.5 | 5iwuA-5iguA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5igu | MACROLIDE2'-PHOSPHOTRANSFERASE II (Escherichiacoli) |
PF01636(APH) | 5 | PHE A 234ALA A 238SER A 276ILE A 277PHE A 280 | None | 0.76A | 5iwuA-5iguA:31.5 | 5iwuA-5iguA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5igu | MACROLIDE2'-PHOSPHOTRANSFERASE II (Escherichiacoli) |
PF01636(APH) | 5 | THR A 221GLU A 222PHE A 234ALA A 238SER A 276 | None | 0.39A | 5iwuA-5iguA:31.5 | 5iwuA-5iguA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k04 | UNCHARACTERIZEDPROTEIN (Candidaalbicans) |
PF09797(NatB_MDM20) | 5 | ILE A 432TYR A 427HIS A 437THR A 466SER A 500 | None | 1.41A | 5iwuA-5k04A:undetectable | 5iwuA-5k04A:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lki | TCDA1 (Photorhabdusluminescens) |
PF03538(VRP1) | 5 | THR A1054GLU A1143PHE A1110ALA A1096ILE A1203 | None | 1.21A | 5iwuA-5lkiA:3.1 | 5iwuA-5lkiA:8.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ng6 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Francisellatularensis) |
no annotation | 5 | ILE A1085HIS A1261ALA A1138ILE A1286MET A1268 | None | 1.13A | 5iwuA-5ng6A:undetectable | 5iwuA-5ng6A:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4n | FRUCTOSE-1 (Neisseriagonorrhoeae) |
PF01116(F_bP_aldolase) | 5 | HIS A 84THR A 196ALA A 51ILE A 46MET A 6 | PO4 A 402 (-3.6A)NoneNoneNoneNone | 1.24A | 5iwuA-5u4nA:undetectable | 5iwuA-5u4nA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zhg | OUTER CAPSID PROTEINVP8* (Rotavirus C) |
no annotation | 5 | ILE A 150HIS A 37PHE A 141SER A 114ILE A 17 | None | 1.35A | 5iwuA-5zhgA:1.4 | 5iwuA-5zhgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ax8 | METHIONINE-TRNALIGASE (Mycobacteriumtuberculosis) |
no annotation | 5 | ILE A 260HIS A 268PHE A 332ALA A 27PHE A 183 | NoneME8 A 801 (-4.6A)NoneNoneNone | 1.44A | 5iwuA-6ax8A:undetectable | 5iwuA-6ax8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6brd | RIFAMPINMONOOXYGENASE (Streptomycesvenezuelae) |
no annotation | 5 | TYR A 403HIS A 90THR A 68ILE A 294MET A 15 | None | 1.26A | 5iwuA-6brdA:undetectable | 5iwuA-6brdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c7y | TYROSINE-PROTEINKINASE JAK1SUPPRESSOR OFCYTOKINE SIGNALING 1 (Homo sapiens;Gallus gallus) |
no annotationno annotation | 5 | ALA B 76SER B 66ILE B 67PHE B 64MET A1099 | None | 1.39A | 5iwuA-6c7yB:undetectable | 5iwuA-6c7yB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emk | SERINE/THREONINE-PROTEIN KINASE TOR2 (Saccharomycescerevisiae) |
no annotation | 5 | HIS A 946GLU A1208ALA A 940SER A 990ILE A 991 | None | 1.35A | 5iwuA-6emkA:1.6 | 5iwuA-6emkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f4f | GLUTATHIONETRANSFERASE (Trametesversicolor) |
no annotation | 5 | ILE A 166TYR A 206PHE A 111ALA A 154SER A 81 | NoneNoneNoneNoneGDN A 301 (-2.6A) | 1.44A | 5iwuA-6f4fA:undetectable | 5iwuA-6f4fA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5o | POLYMERASE ACIDICPROTEIN (Influenza Bvirus) |
no annotation | 5 | ILE A 269HIS A 268TYR A 270SER A 658ILE A 686 | None | 1.42A | 5iwuA-6f5oA:undetectable | 5iwuA-6f5oA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fm9 | UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATEN-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (Homo sapiens) |
no annotation | 5 | ALA A 183SER A 204ILE A 205PHE A 208MET A 228 | NoneP6L A 501 (-3.4A)NoneNoneNone | 1.39A | 5iwuA-6fm9A:undetectable | 5iwuA-6fm9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN5 (Mus musculus) |
no annotation | 5 | ILE L 302PHE L 335SER L 99ILE L 100PHE L 103 | None | 1.32A | 5iwuA-6g2jL:undetectable | 5iwuA-6g2jL:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN5 (Mus musculus) |
no annotation | 5 | THR L 369PHE L 335SER L 99ILE L 100PHE L 103 | None | 1.36A | 5iwuA-6g2jL:undetectable | 5iwuA-6g2jL:undetectable |