SIMILAR PATTERNS OF AMINO ACIDS FOR 5IQC_C_51GC600_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3at7 | ALGINATE-BINDINGFLAGELLIN (Sphingomonassp. A1) |
PF09375(Peptidase_M75) | 5 | ASP A 140TYR A 78GLU A 82GLU A 178GLU A 79 | None | 1.24A | 5iqcC-3at7A:1.3 | 5iqcC-3at7A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3at7 | ALGINATE-BINDINGFLAGELLIN (Sphingomonassp. A1) |
PF09375(Peptidase_M75) | 5 | ASP A 140TYR A 78GLU A 82GLU A 178GLU A 86 | None | 1.09A | 5iqcC-3at7A:1.3 | 5iqcC-3at7A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckz | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | SER A 179ASP A 198GLU A 119GLU A 277GLU A 227 | ZMR A 469 ( 4.6A)NoneZMR A 469 (-3.5A)ZMR A 469 (-3.7A)ZMR A 469 (-3.5A) | 1.47A | 5iqcC-3ckzA:0.0 | 5iqcC-3ckzA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti8 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | SER A 179ASP A 198GLU A 119GLU A 277GLU A 227 | LNV A 901 ( 4.6A)NoneLNV A 901 (-3.6A)LNV A 901 ( 3.8A)LNV A 901 (-3.4A) | 1.46A | 5iqcC-3ti8A:0.0 | 5iqcC-3ti8A:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzz | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | SER A 179ASP A 198GLU A 119GLU A 277GLU A 227 | G39 A 509 ( 4.5A)NoneG39 A 509 (-3.3A)G39 A 509 ( 4.0A)None | 1.48A | 5iqcC-4hzzA:0.8 | 5iqcC-4hzzA:22.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 8 | ASP A 374SER A 376ASP A 396TYR A 408GLU A 411GLU A 416TYR A 448GLU A 451 | GNP A 500 (-4.6A)None MG A 702 ( 4.8A)NoneNoneNoneNoneNone | 0.31A | 5iqcC-6ceyA:43.3 | 5iqcC-6ceyA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 5 | ASP A 393TYR A 408GLU A 411GLU A 415GLU A 416 | MG A 702 (-1.7A)NoneNoneNoneNone | 1.34A | 5iqcC-6ceyA:43.3 | 5iqcC-6ceyA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 6 | TYR A 408GLU A 411GLU A 415GLU A 416TYR A 448GLU A 451 | None | 0.78A | 5iqcC-6ceyA:43.3 | 5iqcC-6ceyA:100.00 |