SIMILAR PATTERNS OF AMINO ACIDS FOR 5IGV_A_ZITA404_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ev1 ECHOVIRUS 1

(Enterovirus B) 		PF00073
(Rhv) 		4 ASN 1 214
ILE 1 259
TYR 1 258
PHE 3 237
 PLM  1   0 (-3.5A)
None
None
None
 1.20A 5igvA-1ev11:
0.0		 5igvA-1ev11:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htq GLUTAMINE SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ASN A  88
ILE A 205
TYR A 223
PHE A 126
 None
 1.27A 5igvA-1htqA:
undetectable		 5igvA-1htqA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		4 ASN A1129
ILE A 945
TYR A 944
PHE A1061
 None
 1.43A 5igvA-1k7yA:
0.0		 5igvA-1k7yA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)

(Ascophyllum
nodosum) 		no annotation 4 ASN A 470
ILE A 501
TYR A 549
PHE A 519
 None
 1.47A 5igvA-1qi9A:
0.7		 5igvA-1qi9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ut9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 ASN A 794
ILE A 711
TYR A 713
PHE A 683
 None
 1.41A 5igvA-1ut9A:
0.0		 5igvA-1ut9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 ASN A 267
ILE A 570
TYR A 532
PHE A 546
 None
 1.21A 5igvA-1xkhA:
0.2		 5igvA-1xkhA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]

(Anaerobiospirillum
succiniciproducens) 		PF01293
(PEPCK_ATP) 		4 ASN A 236
ILE A 452
TYR A 431
PHE A 241
 None
 1.29A 5igvA-1ytmA:
0.0		 5igvA-1ytmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ztv HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF01904
(DUF72) 		4 ASN A 187
ILE A 166
TYR A 182
PHE A 156
 None
 1.30A 5igvA-1ztvA:
undetectable		 5igvA-1ztvA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aky ADENYLATE KINASE

(Saccharomyces
cerevisiae) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 ASN A  23
ILE A 134
TYR A 142
PHE A 146
 None
None
None
AP5  A 301 (-4.7A)
 1.31A 5igvA-2akyA:
undetectable		 5igvA-2akyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayn UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14

(Homo sapiens) 		PF00443
(UCH) 		4 ASN A 339
ILE A 473
TYR A 475
PHE A 277
 None
 1.19A 5igvA-2aynA:
undetectable		 5igvA-2aynA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c5s PROBABLE THIAMINE
BIOSYNTHESIS PROTEIN
THII

(Bacillus
anthracis) 		PF02568
(ThiI)
PF02926
(THUMP) 		4 ASN A  55
ILE A 161
TYR A 160
PHE A  75
 None
 0.91A 5igvA-2c5sA:
undetectable		 5igvA-2c5sA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsj PROTEIN PPL-2

(Parkia
platycephala) 		PF00704
(Glyco_hydro_18) 		4 ASN A 235
ILE A   3
TYR A 263
PHE A 181
 None
 1.44A 5igvA-2gsjA:
undetectable		 5igvA-2gsjA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k6x RNA POLYMERASE SIGMA
FACTOR RPOD

(Thermotoga
maritima) 		PF03979
(Sigma70_r1_1) 		4 ASN A  67
ILE A  83
TYR A  50
PHE A  57
 None
 1.41A 5igvA-2k6xA:
undetectable		 5igvA-2k6xA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nsm CARBOXYPEPTIDASE N
CATALYTIC CHAIN

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg) 		4 ASN A 188
ILE A 285
TYR A 277
PHE A 143
 None
 1.46A 5igvA-2nsmA:
undetectable		 5igvA-2nsmA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5p FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07660
(STN)
PF07715
(Plug) 		4 ASN A 267
ILE A 570
TYR A 532
PHE A 546
 None
 1.23A 5igvA-2o5pA:
0.8		 5igvA-2o5pA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2omk HYPOTHETICAL PROTEIN

(Bacteroides
thetaiotaomicron) 		PF04263
(TPK_catalytic) 		4 ASN A  15
ILE A  99
TYR A 122
PHE A 138
 SNN  A  38 ( 3.4A)
None
None
None
 1.32A 5igvA-2omkA:
undetectable		 5igvA-2omkA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwh SUCROSE ISOMERASE

([Pseudomonas]
mesoacidophila) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 ASN A 373
ILE A 295
TYR A 285
PHE A 280
 None
 1.42A 5igvA-2pwhA:
3.4		 5igvA-2pwhA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxg CG6181-PA, ISOFORM A

(Drosophila
melanogaster) 		no annotation 4 ASN A1232
ILE A1279
TYR A1293
PHE A1249
 None
 1.13A 5igvA-2vxgA:
undetectable		 5igvA-2vxgA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		4 ASN A 245
ILE A  66
TYR A 445
PHE A 304
 None
 1.37A 5igvA-2zwsA:
undetectable		 5igvA-2zwsA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b46 AMINOTRANSFERASE
BNA3

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		4 ASN A 209
ILE A 334
TYR A 333
PHE A 326
 LLP  A 271 ( 4.1A)
None
None
None
 1.50A 5igvA-3b46A:
undetectable		 5igvA-3b46A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE

(Trichormus
variabilis) 		PF08241
(Methyltransf_11) 		4 ASN A 105
ILE A 171
TYR A 187
PHE A 183
 None
 1.37A 5igvA-3ccfA:
undetectable		 5igvA-3ccfA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3drk OLIGOPEPTIDE-BINDING
PROTEIN OPPA

(Lactococcus
lactis) 		PF00496
(SBP_bac_5) 		4 ASN A 540
ILE A 336
TYR A 413
PHE A 493
 None
 1.42A 5igvA-3drkA:
undetectable		 5igvA-3drkA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h3j L-LACTATE
DEHYDROGENASE 1

(Staphylococcus
aureus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ASN A   7
ILE A  36
TYR A  21
PHE A 119
 None
 1.33A 5igvA-3h3jA:
undetectable		 5igvA-3h3jA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1v PROTEIN INVG

(Salmonella
enterica) 		no annotation 4 ASN A 161
ILE A  91
TYR A 102
PHE A  94
 None
 1.37A 5igvA-3j1vA:
undetectable		 5igvA-3j1vA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mfd D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACB

(Bacillus
subtilis) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		4 ASN A 251
ILE A  37
TYR A  48
PHE A 264
 None
 1.49A 5igvA-3mfdA:
undetectable		 5igvA-3mfdA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzy RNA POLYMERASE
SIGMA-H FACTOR

(Fusobacterium
nucleatum) 		PF04542
(Sigma70_r2) 		4 ASN A 183
ILE A  59
TYR A  62
PHE A  74
 None
 1.17A 5igvA-3mzyA:
undetectable		 5igvA-3mzyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0j TYPE III EFFECTOR
HOPU1

(Pseudomonas
syringae group
genomosp. 3) 		no annotation 4 ASN B 211
ILE B 216
TYR B 186
PHE B 180
 None
 1.02A 5igvA-3u0jB:
undetectable		 5igvA-3u0jB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242

(Pyrococcus
horikoshii) 		no annotation 4 ASN A 798
ILE A 735
TYR A 736
PHE A 716
 None
 1.19A 5igvA-3vu1A:
undetectable		 5igvA-3vu1A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wov OLIGOSACCHARYL
TRANSFERASE

(Pyrococcus
abyssi) 		no annotation 4 ASN A 798
ILE A 737
TYR A 738
PHE A 718
 None
 1.11A 5igvA-3wovA:
undetectable		 5igvA-3wovA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4axg EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E

(Drosophila
melanogaster) 		PF01652
(IF4E) 		4 ASN A 192
ILE A 112
TYR A  80
PHE A 127
 None
 1.27A 5igvA-4axgA:
undetectable		 5igvA-4axgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE

([Clostridium]
papyrosolvens) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		4 ASN A 358
ILE A 267
TYR A 264
PHE A  19
 None
 1.45A 5igvA-4fmvA:
2.1		 5igvA-4fmvA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gz8 SEMAPHORIN-3A

(Mus musculus) 		PF01403
(Sema) 		4 ASN A  43
ILE A 503
TYR A 502
PHE A  88
 None
 1.33A 5igvA-4gz8A:
1.7		 5igvA-4gz8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE

(Plasmodium
falciparum) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 ASN A 468
ILE A 314
TYR A 308
PHE A 323
 None
 1.45A 5igvA-4j3bA:
undetectable		 5igvA-4j3bA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1c VACUOLAR CALCIUM ION
TRANSPORTER

(Saccharomyces
cerevisiae) 		PF01699
(Na_Ca_ex) 		4 ASN A 133
ILE A 207
TYR A 211
PHE A 217
 None
 1.24A 5igvA-4k1cA:
undetectable		 5igvA-4k1cA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt3 PUTATIVE LIPOPROTEIN
UNCHARACTERIZED
PROTEIN

(Pseudomonas
protegens) 		PF01832
(Glucosaminidase)
no annotation 		4 ASN B 115
ILE A  77
TYR A  84
PHE A 121
 None
 1.43A 5igvA-4kt3B:
2.2		 5igvA-4kt3B:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uom FAB FRAGMENT HEAVY
CHAIN
FAB FRAGMENT LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ASN L  97
ILE H  34
TYR H  33
PHE H 102
 None
 1.49A 5igvA-4uomL:
undetectable		 5igvA-4uomL:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7f FOLATE ECF
TRANSPORTER

(Enterococcus
faecalis) 		PF12822
(ECF_trnsprt) 		4 ASN A 162
ILE A  47
TYR A  91
PHE A  39
 None
 1.42A 5igvA-4z7fA:
undetectable		 5igvA-4z7fA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN

(Escherichia
coli;
Pyrococcus
furiosus) 		PF13416
(SBP_bac_8) 		4 ASN A 693
ILE A 627
TYR A 628
PHE A 608
 None
 1.47A 5igvA-5azaA:
undetectable		 5igvA-5azaA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5coz UNCHARACTERIZED
PROTEIN

([Eubacterium]
rectale) 		no annotation 4 ASN A 254
ILE A 340
TYR A 285
PHE A 240
 None
 1.50A 5igvA-5cozA:
2.4		 5igvA-5cozA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dvh PCPI-3

(Solanum
tuberosum) 		PF00197
(Kunitz_legume) 		4 ASN A 193
ILE A  80
TYR A  63
PHE A  71
 None
 1.49A 5igvA-5dvhA:
undetectable		 5igvA-5dvhA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01547
(SBP_bac_1) 		4 ASN A 180
ILE A 247
TYR A 271
PHE A 277
 None
 1.07A 5igvA-5g5zA:
undetectable		 5igvA-5g5zA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hrm HALOALKYLPHOSPHORUS
HYDROLASE

(Sphingobium sp.
TCM1) 		no annotation 4 ASN A 308
ILE A 362
TYR A 361
PHE A 302
 None
 1.12A 5igvA-5hrmA:
0.2		 5igvA-5hrmA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ioj HALOALKYLPHOSPHORUS
HYDROLASE

(Sphingobium sp.
TCM1) 		no annotation 4 ASN A 308
ILE A 362
TYR A 361
PHE A 302
 None
 1.15A 5igvA-5iojA:
2.2		 5igvA-5iojA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1t TORSIN-1A

(Homo sapiens) 		PF06309
(Torsin) 		4 ASN A  89
ILE A  79
TYR A 265
PHE A 203
 None
 1.35A 5igvA-5j1tA:
undetectable		 5igvA-5j1tA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldd CCZ1
MON1

(Chaetomium
thermophilum) 		PF03164
(Mon1)
PF08217
(DUF1712) 		4 ASN A 204
ILE A 227
TYR A 225
PHE B 118
 None
 1.22A 5igvA-5lddA:
undetectable		 5igvA-5lddA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npy FLAGELLAR BASAL BODY
PROTEIN

(Helicobacter
pylori) 		no annotation 4 ASN A 226
ILE A 240
TYR A 266
PHE A 264
 144  A 701 (-4.3A)
None
None
None
 1.44A 5igvA-5npyA:
undetectable		 5igvA-5npyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		4 ASN T3732
ILE T3720
TYR T3560
PHE T3555
 None
 1.38A 5igvA-5ojsT:
undetectable		 5igvA-5ojsT:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sva DNA REPAIR HELICASE
RAD3

(Saccharomyces
cerevisiae) 		PF06733
(DEAD_2)
PF06777
(HBB)
PF13307
(Helicase_C_2) 		4 ASN Y 239
ILE Y  70
TYR Y  71
PHE Y 178
 None
 1.05A 5igvA-5svaY:
undetectable		 5igvA-5svaY:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t47 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E

(Drosophila
melanogaster) 		PF01652
(IF4E) 		4 ASN A 192
ILE A 112
TYR A  80
PHE A 127
 None
 1.27A 5igvA-5t47A:
undetectable		 5igvA-5t47A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5th3 R-SWAI PROTEIN

(Staphylococcus
warneri) 		no annotation 4 ASN A 122
ILE A  52
TYR A  61
PHE A  83
 None
 1.21A 5igvA-5th3A:
undetectable		 5igvA-5th3A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fc3 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E

(Saccharomyces
cerevisiae) 		no annotation 4 ASN A 161
ILE A  81
TYR A  47
PHE A  96
 None
 1.31A 5igvA-6fc3A:
undetectable		 5igvA-6fc3A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fls -

(-) 		no annotation 4 ASN A 121
ILE A 108
TYR A 126
PHE A 167
 None
None
GOL  A 304 (-3.7A)
None
 1.43A 5igvA-6flsA:
undetectable		 5igvA-6flsA:
undetectable