SIMILAR PATTERNS OF AMINO ACIDS FOR 5IGJ_A_CTYA402
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a2o | CHEB METHYLESTERASE (Salmonellaenterica) |
PF00072(Response_reg)PF01339(CheB_methylest) | 5 | ILE A 135VAL A 52MET A 81VAL A 80GLY A 64 | None | 1.09A | 5igjA-1a2oA:0.0 | 5igjA-1a2oA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6d | THERMOSOME (ALPHASUBUNIT) (Thermoplasmaacidophilum) |
PF00118(Cpn60_TCP1) | 5 | ILE A 154VAL A 179GLU A 385ALA A 195VAL A 192 | None | 1.01A | 5igjA-1a6dA:0.0 | 5igjA-1a6dA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fpw | CALCIUM-BINDINGPROTEIN NCS-1 (Saccharomycescerevisiae) |
PF13499(EF-hand_7)PF13833(EF-hand_8) | 5 | MET A 121ILE A 116ASP A 187VAL A 125ALA A 182 | None CA A 501 (-4.6A)NoneNoneNone | 0.98A | 5igjA-1fpwA:undetectable | 5igjA-1fpwA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hrd | GLUTAMATEDEHYDROGENASE ([Clostridium]symbiosum) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ILE A 53ASP A 17TYR A 15VAL A 11VAL A 25 | None | 1.01A | 5igjA-1hrdA:0.0 | 5igjA-1hrdA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ia7 | CELLULASE CEL9M ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9) | 5 | ASP A 414ALA A 311ALA A 312MET A 315VAL A 316 | SO4 A1335 ( 4.3A)NoneNoneNoneNone | 1.11A | 5igjA-1ia7A:undetectable | 5igjA-1ia7A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q3t | CYTIDYLATE KINASE (Streptococcuspneumoniae) |
PF02224(Cytidylate_kin) | 5 | VAL A 121GLU A 131ALA A 53ALA A 54GLY A 95 | None | 0.86A | 5igjA-1q3tA:0.0 | 5igjA-1q3tA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgc | PROTEIN (VIRUSCAPSID PROTEIN VP1)PROTEIN (VIRUSCAPSID PROTEIN VP2) (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ILE 2 197VAL 2 109VAL 2 123GLY 1 5THR 1 4 | None | 1.01A | 5igjA-1qgc2:0.0 | 5igjA-1qgc2:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qy9 | HYPOTHETICAL PROTEINYDDE (Escherichiacoli) |
PF02567(PhzC-PhzF) | 5 | ILE A 60VAL A 82GLU A 108ALA A 285VAL A 8 | None | 0.92A | 5igjA-1qy9A:0.0 | 5igjA-1qy9A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1si1 | IRON BINDING PROTEINFBPA (Mannheimiahaemolytica) |
PF13343(SBP_bac_6) | 5 | ILE A 194ALA A 303ALA A 304VAL A 308GLY A 155 | None | 0.68A | 5igjA-1si1A:0.0 | 5igjA-1si1A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulz | PYRUVATE CARBOXYLASEN-TERMINAL DOMAIN (Aquifexaeolicus) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ILE A 51VAL A 29ALA A 74VAL A 72GLY A 98 | None | 0.96A | 5igjA-1ulzA:undetectable | 5igjA-1ulzA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vfw | PROTEIN (FUSIONPROTEIN CONSISTINGOF KINESIN-LIKEPROTEIN KIF1A,KINESIN HEAVY CHAINISOFORM 5C AND A HISTAG (Mus musculus) |
PF00225(Kinesin) | 5 | ILE A 354VAL A 8ALA A 330ALA A 329GLY A 251 | NoneNoneNoneNoneANP A 500 (-3.4A) | 1.02A | 5igjA-1vfwA:undetectable | 5igjA-1vfwA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w5d | PENICILLIN-BINDINGPROTEIN (Bacillussubtilis) |
PF02113(Peptidase_S13) | 5 | ASP A 105ALA A 249ALA A 159GLY A 95THR A 74 | None | 1.00A | 5igjA-1w5dA:undetectable | 5igjA-1w5dA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2anp | LEUCYLAMINOPEPTIDASE (Vibrioproteolyticus) |
PF04389(Peptidase_M28) | 5 | GLU A 245ALA A 123ALA A 124VAL A 128GLY A 269 | None | 0.89A | 5igjA-2anpA:undetectable | 5igjA-2anpA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2au1 | IGG-DEGRADINGPROTEASE (Streptococcuspyogenes) |
PF09028(Mac-1) | 5 | GLU A 154ALA A 97ALA A 96VAL A 171THR A 85 | None | 1.10A | 5igjA-2au1A:undetectable | 5igjA-2au1A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cq1 | PTB-LIKE PROTEIN L (Homo sapiens) |
no annotation | 5 | ALA A 106ALA A 107MET A 110VAL A 111THR A 86 | None | 0.57A | 5igjA-2cq1A:2.0 | 5igjA-2cq1A:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dq3 | SERYL-TRNASYNTHETASE (Aquifexaeolicus) |
PF00587(tRNA-synt_2b)PF02403(Seryl_tRNA_N) | 5 | ILE A 276ASP A 336VAL A 339ALA A 306GLY A 384 | NoneNoneNoneNoneSSA A1001 (-3.7A) | 1.07A | 5igjA-2dq3A:0.1 | 5igjA-2dq3A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2htm | THIAZOLEBIOSYNTHESIS PROTEINTHIG (Thermusthermophilus) |
PF05690(ThiG) | 5 | VAL A 196ALA A 154ALA A 153VAL A 183GLY A 157 | None | 1.06A | 5igjA-2htmA:undetectable | 5igjA-2htmA:25.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2id1 | HYPOTHETICAL PROTEIN (Chromobacteriumviolaceum) |
PF02410(RsfS) | 5 | VAL A 80GLU A 76ALA A 50ALA A 52VAL A 55 | None | 1.10A | 5igjA-2id1A:undetectable | 5igjA-2id1A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ldx | APO-LACTATEDEHYDROGENASE (Mus musculus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ILE A 199VAL A 303VAL A 269GLY A 159THR A 143 | None | 1.10A | 5igjA-2ldxA:undetectable | 5igjA-2ldxA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m5y | PUTATIVE TUBERCULINRELATED PEPTIDE (Mycobacteriumtuberculosis) |
PF13399(LytR_C) | 5 | VAL A 118GLU A 108ALA A 91VAL A 94GLY A 86 | None | 1.02A | 5igjA-2m5yA:undetectable | 5igjA-2m5yA:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mki | CYTOPLASMICPOLYADENYLATIONELEMENT-BINDINGPROTEIN 4 (Homo sapiens) |
PF16367(RRM_7) | 5 | VAL A 250ALA A 230ALA A 231VAL A 237GLY A 199 | None | 1.06A | 5igjA-2mkiA:undetectable | 5igjA-2mkiA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n3o | POLYPYRIMIDINETRACT-BINDINGPROTEIN 1 (Homo sapiens) |
no annotation | 6 | GLU A 135ALA A 106ALA A 107MET A 110VAL A 111THR A 86 | None | 1.02A | 5igjA-2n3oA:1.1 | 5igjA-2n3oA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2obn | HYPOTHETICAL PROTEIN (Trichormusvariabilis) |
PF07755(DUF1611)PF17396(DUF1611_N) | 5 | ILE A 129VAL A 75GLU A 66ALA A 38ALA A 10 | None | 1.10A | 5igjA-2obnA:undetectable | 5igjA-2obnA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ola | O-SUCCINYLBENZOICACID SYNTHETASE (Staphylococcusaureus) |
PF13378(MR_MLE_C) | 5 | ILE A 34VAL A 104ALA A 85ALA A 86VAL A 90 | None | 0.99A | 5igjA-2olaA:undetectable | 5igjA-2olaA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ols | PHOSPHOENOLPYRUVATESYNTHASE (Neisseriameningitidis) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | ALA A 46ALA A 188VAL A 124GLY A 21THR A 129 | None | 1.07A | 5igjA-2olsA:undetectable | 5igjA-2olsA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ovl | PUTATIVE RACEMASE (Streptomycescoelicolor) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 109VAL A 36ALA A 61VAL A 64GLY A 56 | None | 1.01A | 5igjA-2ovlA:undetectable | 5igjA-2ovlA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pff | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00106(adh_short)PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ILE A1200ALA A1587ALA A1382VAL A1027GLY A1248 | None | 1.06A | 5igjA-2pffA:undetectable | 5igjA-2pffA:9.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pff | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00106(adh_short)PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ILE A1200ALA A1587ALA A1382VAL A1027GLY A1330 | None | 1.06A | 5igjA-2pffA:undetectable | 5igjA-2pffA:9.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz9 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Vibrio cholerae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | ILE A 107VAL A 93ALA A 9ALA A 71GLY A 12 | None | 1.00A | 5igjA-2qz9A:undetectable | 5igjA-2qz9A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vr2 | DIHYDROPYRIMIDINASE (Homo sapiens) |
PF01979(Amidohydro_1) | 5 | ASP A 17TYR A 389ALA A 382ALA A 383GLY A 63 | None | 1.10A | 5igjA-2vr2A:undetectable | 5igjA-2vr2A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xf8 | D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | ILE A 214VAL A 157ALA A 290VAL A 309GLY A 316 | None | 1.02A | 5igjA-2xf8A:undetectable | 5igjA-2xf8A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yev | CYTOCHROME C OXIDASEPOLYPEPTIDE I+IIICYTOCHROME C OXIDASESUBUNIT 2 (Thermusthermophilus) |
PF00034(Cytochrom_C)PF00115(COX1)PF00116(COX2)PF00510(COX3)PF02790(COX2_TM) | 5 | ILE B 161ALA A 214ALA A 215VAL A 219GLY A 638 | None | 0.74A | 5igjA-2yevB:undetectable | 5igjA-2yevB:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yq4 | D-ISOMER SPECIFIC2-HYDROXYACIDDEHYDROGENASE (Lactobacillusdelbrueckii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ILE A 84VAL A 49ALA A 322VAL A 71GLY A 325 | None | 1.09A | 5igjA-2yq4A:undetectable | 5igjA-2yq4A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzj | GLUCURONAN LYASE A (Trichodermareesei) |
PF14099(Polysacc_lyase) | 5 | ILE A 112TYR A 221VAL A 197ALA A 37VAL A 224 | None | 1.10A | 5igjA-2zzjA:undetectable | 5igjA-2zzjA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3akf | PUTATIVE SECRETEDALPHAL-ARABINOFURANOSIDASE II (Streptomycesavermitilis) |
PF04616(Glyco_hydro_43)PF05270(AbfB) | 5 | ILE A 83TYR A 90VAL A 89ALA A 77GLY A 197 | NoneNoneNoneGOL A 591 ( 4.4A) NA A 502 ( 4.7A) | 0.99A | 5igjA-3akfA:undetectable | 5igjA-3akfA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8l | FTSZ-LIKE PROTEIN OFUNKNOWN FUNCTION (Nostocpunctiforme) |
PF09585(Lin0512_fam) | 5 | GLU A 65ALA A 24ALA A 25VAL A 29GLY A 89 | None | 0.80A | 5igjA-3c8lA:undetectable | 5igjA-3c8lA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1r | FRUCTOSE-1,6-BISPHOSPHATASE CLASS IIGLPX (Escherichiacoli) |
PF03320(FBPase_glpX) | 5 | ILE A 53ASP A 33ALA A 17ALA A 16VAL A 12 | None CA A 337 (-2.7A)NoneNoneNone | 0.96A | 5igjA-3d1rA:undetectable | 5igjA-3d1rA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm5 | SIGNAL RECOGNITION54 KDA PROTEIN (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 5 | ILE A 102VAL A 133GLU A 164ALA A 143VAL A 117 | None | 1.05A | 5igjA-3dm5A:undetectable | 5igjA-3dm5A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e53 | FATTY-ACID-COALIGASE FADD28 (Mycobacteriumtuberculosis) |
PF00501(AMP-binding) | 5 | ILE A 457ASP A 222VAL A 338ALA A 411VAL A 405 | None | 1.05A | 5igjA-3e53A:undetectable | 5igjA-3e53A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fk3 | PROTEIN AF-9 HOMOLOG (Saccharomycescerevisiae) |
PF03366(YEATS) | 5 | ILE A 153ASP A 54VAL A 47ALA A 79VAL A 62 | None | 1.03A | 5igjA-3fk3A:undetectable | 5igjA-3fk3A:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrd | NICOTINATEDEHYDROGENASE MEDIUMMOLYBDOPTERINSUBUNIT (Eubacteriumbarkeri) |
PF02738(Ald_Xan_dh_C2) | 5 | ILE B 30VAL B 38ALA B 25ALA B 26VAL B 97 | None | 1.00A | 5igjA-3hrdB:undetectable | 5igjA-3hrdB:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6d | PROTOPORPHYRINOGENOXIDASE (Bacillussubtilis) |
PF01593(Amino_oxidase) | 5 | VAL A 314ALA A 344VAL A 387GLY A 331THR A 330 | None | 0.96A | 5igjA-3i6dA:undetectable | 5igjA-3i6dA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3juj | UDP-GLUCOSEPYROPHOSPHORYLASE(GALU) (Helicobacterpylori) |
PF00483(NTP_transferase) | 5 | ILE A 230ALA A 10VAL A 54GLY A 13THR A 14 | None | 1.10A | 5igjA-3jujA:undetectable | 5igjA-3jujA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l2z | BIRA BIFUNCTIONALPROTEIN (Mycobacteriumtuberculosis) |
PF02237(BPL_C)PF03099(BPL_LplA_LipB) | 5 | ILE A 59VAL A 155ALA A 104ALA A 105VAL A 109 | None | 0.90A | 5igjA-3l2zA:undetectable | 5igjA-3l2zA:24.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lgs | 5'-METHYLTHIOADENOSINE NUCLEOSIDASES (Arabidopsisthaliana) |
PF01048(PNP_UDP_1) | 5 | ASP A 179ALA A 204ALA A 205VAL A 209GLY A 152 | None | 1.06A | 5igjA-3lgsA:undetectable | 5igjA-3lgsA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nhi | D7 PROTEIN (Anophelesstephensi) |
PF01395(PBP_GOBP) | 5 | ILE A 75TYR A 117VAL A 120ALA A 116GLY A 108 | NoneEAH A 1 (-4.6A)NoneNoneNone | 1.10A | 5igjA-3nhiA:undetectable | 5igjA-3nhiA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qkg | PROTEIN AMBP (Homo sapiens) |
PF00061(Lipocalin) | 5 | MET A 163ILE A 30VAL A 46GLU A 74GLY A 23 | None | 1.09A | 5igjA-3qkgA:undetectable | 5igjA-3qkgA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rhg | PUTATIVEPHOPHOTRIESTERASE (Proteusmirabilis) |
PF02126(PTE) | 5 | ILE A 74ALA A 161ALA A 121VAL A 119GLY A 153 | None | 1.03A | 5igjA-3rhgA:undetectable | 5igjA-3rhgA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t12 | GLIDING PROTEIN MGLB (Thermusthermophilus) |
PF03259(Robl_LC7) | 5 | VAL B 96GLU B 101ALA B 68ALA B 67VAL B 63 | None | 1.05A | 5igjA-3t12B:undetectable | 5igjA-3t12B:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3toe | DNA/RNA-BINDINGPROTEIN ALBA (Methanothermobacterthermautotrophicus) |
PF01918(Alba) | 5 | ILE A 61ASP A 46VAL A 51VAL A 21GLY A 10 | None | 1.10A | 5igjA-3toeA:undetectable | 5igjA-3toeA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubo | ADENOSINE KINASE (Sinorhizobiummeliloti) |
PF00294(PfkB) | 5 | ILE A 211VAL A 6ALA A 65VAL A 68GLY A 59 | NoneNoneNoneNoneADN A 353 (-3.2A) | 1.08A | 5igjA-3uboA:undetectable | 5igjA-3uboA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vs8 | TYPE III POLYKETIDESYNTHASE (Azotobactervinelandii) |
PF02797(Chal_sti_synt_C) | 5 | VAL A 178ALA A 164MET A 167VAL A 168GLY A 135 | None | 0.98A | 5igjA-3vs8A:undetectable | 5igjA-3vs8A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w25 | GLYCOSIDE HYDROLASEFAMILY 10 (Thermoanaerobacteriumsaccharolyticum) |
PF00331(Glyco_hydro_10) | 5 | MET A 201ILE A 191VAL A 205VAL A 245GLY A 140 | None | 1.08A | 5igjA-3w25A:undetectable | 5igjA-3w25A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zbf | PROTO-ONCOGENETYROSINE-PROTEINKINASE ROS (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | VAL A2015GLU A1990ALA A1998MET A2001GLY A2104 | None | 1.03A | 5igjA-3zbfA:6.8 | 5igjA-3zbfA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zou | FARNESYLPYROPHOSPHATESYNTHASE (Pseudomonasaeruginosa) |
PF00348(polyprenyl_synt) | 5 | ILE A 2VAL A 291ALA A 217GLY A 182THR A 181 | 6H6 A1299 ( 4.1A)NoneNoneNoneNone | 1.07A | 5igjA-3zouA:undetectable | 5igjA-3zouA:26.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4am3 | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE (Caulobactervibrioides) |
PF00013(KH_1)PF01138(RNase_PH)PF03725(RNase_PH_C)PF03726(PNPase) | 5 | ILE A 193VAL A 463GLU A 530MET A 442VAL A 445 | None | 1.00A | 5igjA-4am3A:undetectable | 5igjA-4am3A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4av6 | K(+)-STIMULATEDPYROPHOSPHATE-ENERGIZED SODIUM PUMP (Thermotogamaritima) |
PF03030(H_PPase) | 5 | ILE A 706ALA A 443ALA A 444MET A 447GLY A 427 | None | 1.10A | 5igjA-4av6A:undetectable | 5igjA-4av6A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhg | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Thermobisporabispora) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 88VAL A 84ALA A 62ALA A 61VAL A 108 | None | 1.04A | 5igjA-4dhgA:undetectable | 5igjA-4dhgA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e09 | PLASMID PARTITIONINGPROTEIN PARF (Escherichiacoli) |
PF01656(CbiA) | 5 | ILE A 102VAL A 19GLU A 195VAL A 35GLY A 30 | None | 1.09A | 5igjA-4e09A:undetectable | 5igjA-4e09A:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3a | SUGAR KINASE PROTEIN (Rhizobium etli) |
PF00294(PfkB) | 5 | ILE A 209VAL A 4ALA A 63VAL A 66GLY A 57 | NoneNoneNoneNoneADN A 500 (-3.7A) | 1.07A | 5igjA-4e3aA:undetectable | 5igjA-4e3aA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gh4 | CAPSID PROTEIN VP1CAPSID PROTEIN VP2 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ILE B 197VAL B 109VAL B 123GLY A 5THR A 4 | None | 1.04A | 5igjA-4gh4B:undetectable | 5igjA-4gh4B:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxy | PLM1 (Streptomycessp. HK803) |
PF08659(KR) | 5 | VAL A 57GLU A 30ALA A 69ALA A 70VAL A 74 | None | 0.95A | 5igjA-4hxyA:undetectable | 5igjA-4hxyA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6j | F-BOX/LRR-REPEATPROTEIN 3 (Homo sapiens) |
PF12937(F-box-like) | 5 | ILE B 392VAL B 380GLU B 349ALA B 355GLY B 328 | None | 0.89A | 5igjA-4i6jB:undetectable | 5igjA-4i6jB:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iv6 | ACYL-COADEHYDROGENASE FADE3 (Mycolicibacteriumsmegmatis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | ILE A 359ASP A 332ALA A 256VAL A 252GLY A 288 | None | 1.06A | 5igjA-4iv6A:undetectable | 5igjA-4iv6A:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqk | NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLEPHOSPHORIBOSYLTRANSFERASE (Salmonellaenterica) |
PF02277(DBI_PRT) | 5 | ILE A 137GLU A 149ALA A 274ALA A 273GLY A 248 | None | 0.99A | 5igjA-4kqkA:undetectable | 5igjA-4kqkA:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lx4 | ENDOGLUCANASE(ENDO-1,4-BETA-GLUCANASE)PROTEIN (Pseudomonasstutzeri) |
PF00150(Cellulase) | 5 | ILE A 202ALA A 155ALA A 156VAL A 160GLY A 102 | None | 0.82A | 5igjA-4lx4A:undetectable | 5igjA-4lx4A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mch | URIDINEPHOSPHORYLASE (Aliivibriofischeri) |
PF01048(PNP_UDP_1) | 5 | ILE A 60VAL A 85GLU A 135ALA A 128ALA A 197 | None | 1.08A | 5igjA-4mchA:undetectable | 5igjA-4mchA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mio | INOSITOL2-DEHYDROGENASE/D-CHIRO-INOSITOL3-DEHYDROGENASE (Lactobacilluscasei) |
PF01408(GFO_IDH_MocA) | 5 | ILE A 67ALA A 40ALA A 41VAL A 45GLY A 11 | NoneNAI A 401 ( 4.5A)NoneNoneNAI A 401 (-3.3A) | 1.07A | 5igjA-4mioA:undetectable | 5igjA-4mioA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2w | E3 UBIQUITIN-PROTEINLIGASE HERC1 (Homo sapiens) |
PF00415(RCC1) | 5 | VAL A4296ALA A4192ALA A4245VAL A4252GLY A4142 | None | 1.09A | 5igjA-4o2wA:undetectable | 5igjA-4o2wA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o3s | DNA POLYMERASE ETA (Homo sapiens) |
PF00817(IMS)PF11799(IMS_C) | 5 | MET A 200ILE A 196ALA A 112ALA A 117VAL A 12 | None | 0.94A | 5igjA-4o3sA:undetectable | 5igjA-4o3sA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4olo | BMC DOMAIN PROTEIN (Clostridialesbacterium1_7_47FAA) |
PF00936(BMC) | 5 | ILE A 63GLU A 84ALA A 55ALA A 52GLY A 57 | None | 1.09A | 5igjA-4oloA:undetectable | 5igjA-4oloA:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pk1 | CHIMERA PROTEIN OFOUTER MEMBRANEPROTEIN ASSEMBLYFACTORS BAMA ANDBAMB (Escherichiacoli) |
PF07244(POTRA)PF13360(PQQ_2) | 5 | ILE A1390ALA A1075ALA A1074VAL A1072GLY A1053 | None | 1.10A | 5igjA-4pk1A:undetectable | 5igjA-4pk1A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qvg | SIBL (Streptosporangiumsibiricum) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 5 | TYR A 134ALA A 139ALA A 138GLY A 128THR A 129 | None | 1.05A | 5igjA-4qvgA:undetectable | 5igjA-4qvgA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r27 | GLYCOSIDE HYDROLASE (Microbacteriumsp. Gsoil167) |
PF00232(Glyco_hydro_1) | 5 | ILE A 389GLU A 141ALA A 202ALA A 201GLY A 193 | None | 1.01A | 5igjA-4r27A:undetectable | 5igjA-4r27A:24.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ru4 | TAIL SPIKE PROTEINGP49 (Pseudomonasvirus LKA1) |
PF13229(Beta_helix) | 5 | TYR A 318VAL A 470GLU A 336ALA A 364GLY A 360 | None | 1.05A | 5igjA-4ru4A:undetectable | 5igjA-4ru4A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y96 | TRIOSEPHOSPHATEISOMERASE (Gemmataobscuriglobus) |
PF00121(TIM) | 5 | ILE A 250ALA A 190ALA A 187VAL A 232GLY A 132 | None | 0.97A | 5igjA-4y96A:undetectable | 5igjA-4y96A:24.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxs | VIRION EGRESSPROTEIN UL31 (Humanalphaherpesvirus1) |
PF02718(Herpes_UL31) | 5 | MET B 234ILE B 231VAL B 188VAL B 256THR B 251 | None NA B 402 (-3.8A)NoneNoneNone | 0.90A | 5igjA-4zxsB:0.8 | 5igjA-4zxsB:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5l | D-FRUCTOSE1,6-BISPHOSPHATASECLASS2/SEDOHEPTULOSE1,7-BISPHOSPHATASE (Thermosynechococcuselongatus) |
PF03320(FBPase_glpX) | 5 | ILE A 53ASP A 33ALA A 17ALA A 16VAL A 12 | None MG A1341 (-3.3A)NoneNoneNone | 1.08A | 5igjA-5a5lA:undetectable | 5igjA-5a5lA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8d | CARBOHYDRATE BINDINGFAMILY 6 (Ruminiclostridiumthermocellum) |
PF04616(Glyco_hydro_43) | 5 | MET A 310ILE A 318ALA A 45ALA A 274GLY A 168 | NoneNoneGOL A1340 (-3.6A)GOL A1340 (-3.0A)GOL A1340 (-3.3A) | 1.09A | 5igjA-5a8dA:undetectable | 5igjA-5a8dA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5coa | IRIDOID SYNTHASE (Catharanthusroseus) |
no annotation | 5 | ILE A 145GLU A 256ALA A 267VAL A 271GLY A 363 | None | 1.08A | 5igjA-5coaA:undetectable | 5igjA-5coaA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey5 | LBCA-B (syntheticconstruct) |
PF00291(PALP) | 5 | ASP B 326ALA B 266ALA B 265GLY B 262THR B 261 | None | 1.04A | 5igjA-5ey5B:undetectable | 5igjA-5ey5B:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fby | SEPARASE (Chaetomiumthermophilum) |
PF03568(Peptidase_C50) | 5 | VAL A2189ALA A2205ALA A2206VAL A2139THR A2146 | None | 1.02A | 5igjA-5fbyA:undetectable | 5igjA-5fbyA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flw | EXO-BETA-1,3-GALACTANASE (Bifidobacteriumbifidum) |
PF04616(Glyco_hydro_43) | 5 | ILE A 172VAL A 113GLU A 82VAL A 96GLY A 24 | None | 0.91A | 5igjA-5flwA:undetectable | 5igjA-5flwA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ica | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF04003(Utp12)PF08625(Utp13) | 5 | ILE B 806GLU A 916ALA A 922ALA A 923VAL A 927 | None | 1.09A | 5igjA-5icaB:undetectable | 5igjA-5icaB:19.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5igp | MACROLIDE2'-PHOSPHOTRANSFERASE (Escherichiacoli) |
PF01636(APH) | 12 | MET A 103ILE A 105ASP A 200TYR A 202VAL A 203GLU A 222ALA A 233ALA A 234MET A 237VAL A 238GLY A 273THR A 276 | ERY A 402 (-2.2A)ERY A 402 ( 4.4A)ERY A 402 (-2.4A)ERY A 402 (-2.7A)NoneERY A 402 ( 3.9A)ERY A 402 ( 3.9A)ERY A 402 ( 3.2A)ERY A 402 ( 3.0A)ERY A 402 ( 4.7A)ERY A 402 ( 3.6A)ERY A 402 ( 3.8A) | 0.40A | 5igjA-5igpA:48.1 | 5igjA-5igpA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihs | ENDOGLUCANASE,GLYCOSIDE HYDROLASEFAMILY 5 PROTEIN (Cytophagahutchinsonii) |
PF00150(Cellulase) | 5 | VAL A 156GLU A 101ALA A 134ALA A 135VAL A 177 | None | 1.07A | 5igjA-5ihsA:undetectable | 5igjA-5ihsA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jou | ALPHA-XYLOSIDASEBOGH31A (Bacteroidesovatus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 5 | ILE A 198GLU A 100ALA A 103VAL A 112GLY A 119 | NoneEDO A1007 ( 4.9A)NoneNoneNone | 1.05A | 5igjA-5jouA:1.1 | 5igjA-5jouA:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpd | 26S PROTEASOMEREGULATORY SUBUNITRPN7 (Saccharomycescerevisiae) |
PF01399(PCI)PF10602(RPN7) | 5 | ILE R 271GLU R 332ALA R 227ALA R 228VAL R 232 | None | 0.98A | 5igjA-5mpdR:undetectable | 5igjA-5mpdR:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nth | PUTATIVEAMINOPEPTIDASE (Leishmaniamajor) |
PF00883(Peptidase_M17) | 5 | ASP A 119VAL A 152ALA A 124VAL A 142GLY A 82 | None | 0.93A | 5igjA-5nthA:undetectable | 5igjA-5nthA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | METHYL-VIOLOGENREDUCINGHYDROGENASE, SUBUNITG (Methanothermococcusthermolithotrophicus) |
PF01058(Oxidored_q6) | 5 | ILE E 4VAL E 79ALA E 87ALA E 81GLY E 148 | NoneNoneACT E 301 (-4.3A)ACT E 301 ( 4.5A)None | 0.89A | 5igjA-5odrE:undetectable | 5igjA-5odrE:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oji | DEHYDROGENASE/REDUCTASE SDR FAMILYMEMBER 4 (Caenorhabditiselegans) |
no annotation | 5 | ILE A 39VAL A 93GLU A 138ALA A 238VAL A 234 | None | 0.91A | 5igjA-5ojiA:undetectable | 5igjA-5ojiA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olc | GALACTONATEDEHYDRATASE (Zobelliagalactanivorans) |
no annotation | 5 | ILE A 265ALA A 306ALA A 307VAL A 311GLY A 275 | None | 0.74A | 5igjA-5olcA:undetectable | 5igjA-5olcA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tch | TRYPTOPHAN SYNTHASEBETA CHAIN (Mycobacteriumtuberculosis) |
PF00291(PALP) | 5 | ASP B 343ALA B 283ALA B 282GLY B 279THR B 278 | None | 1.10A | 5igjA-5tchB:undetectable | 5igjA-5tchB:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tj3 | ALKALINE PHOSPHATASEPAFA (Elizabethkingiameningoseptica) |
PF01663(Phosphodiest) | 5 | ILE A 86VAL A 523GLU A 542VAL A 32GLY A 64 | None | 0.99A | 5igjA-5tj3A:undetectable | 5igjA-5tj3A:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uco | 2,4,6-TRIHYDROXYBENZOPHENONE SYNTHASE (Hypericumandrosaemum) |
no annotation | 5 | ILE A 313VAL A 383MET A 287VAL A 286GLY A 372 | None | 1.08A | 5igjA-5ucoA:undetectable | 5igjA-5ucoA:10.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wgc | DAUNORUBICIN-DOXORUBICIN POLYKETIDESYNTHASE (Streptomycespeucetius) |
no annotation | 6 | ASP A 302VAL A 164ALA A 166MET A 149GLY A 146THR A 145 | None | 1.33A | 5igjA-5wgcA:undetectable | 5igjA-5wgcA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6amz | 2,3,4,5-TETRAHYDROPYRIDINE-2,6-DICARBOXYLATEN-SUCCINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00132(Hexapep)PF14602(Hexapep_2)PF14805(THDPS_N_2) | 5 | ILE A 178VAL A 227ALA A 249ALA A 250VAL A 233 | None | 1.08A | 5igjA-6amzA:undetectable | 5igjA-6amzA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT CALTERNATIVE COMPLEXIII SUBUNIT D (Flavobacteriumjohnsoniae) |
no annotation | 5 | VAL C 177ALA D 111ALA D 112MET D 115VAL D 116 | None | 0.96A | 5igjA-6btmC:undetectable | 5igjA-6btmC:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ch3 | FLAGELLARBIOSYNTHESIS PROTEINFLHA (Salmonellaenterica) |
no annotation | 6 | MET A 365ILE A 420VAL A 367MET A 374VAL A 375GLY A 435 | None | 1.43A | 5igjA-6ch3A:undetectable | 5igjA-6ch3A:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fht | BACTERIOPHYTOCHROME,ADENYLATE CYCLASE (Deinococcusradiodurans;Synechocystissp. PCC 6803) |
no annotation | 5 | ILE A 675GLU A 648ALA A 609VAL A 613GLY A 600 | None | 1.10A | 5igjA-6fhtA:undetectable | 5igjA-6fhtA:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a2v | METHYLAMINE OXIDASE (Ogataea angusta) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 4 | PRO A 582HIS A 618LEU A 409PHE A 293 | None | 1.41A | 5igjA-1a2vA:0.1 | 5igjA-1a2vA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ad3 | ALDEHYDEDEHYDROGENASE (CLASS3) (Rattusnorvegicus) |
PF00171(Aldedh) | 4 | PRO A 138LEU A 70TYR A 412PHE A 401 | None | 1.43A | 5igjA-1ad3A:0.0 | 5igjA-1ad3A:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASELARGE SUBUNIT[NIFE] HYDROGENASESMALL SUBUNIT (Desulfovibriodesulfuricans) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | PRO A 151HIS B 112LEU A 35TYR A 28 | FSX A 269 (-3.8A)NoneNoneNone | 1.37A | 5igjA-1e3dA:undetectable | 5igjA-1e3dA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gc7 | RADIXIN (Mus musculus) |
PF00373(FERM_M)PF09379(FERM_N)PF09380(FERM_C) | 4 | PRO A 154LEU A 234TYR A 201PHE A 85 | PRO A 154 ( 1.1A)LEU A 234 ( 0.6A)TYR A 201 ( 1.3A)PHE A 85 ( 1.3A) | 1.26A | 5igjA-1gc7A:undetectable | 5igjA-1gc7A:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hjv | CHITINASE-3 LIKEPROTEIN 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | PRO A 142LEU A 254TYR A 243PHE A 234 | None | 1.24A | 5igjA-1hjvA:undetectable | 5igjA-1hjvA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k26 | NUDIX HOMOLOG (Pyrobaculumaerophilum) |
PF00293(NUDIX) | 4 | PRO A 38HIS A 31TYR A 27PHE A 122 | NoneIR3 A 206 (-4.0A)NoneGOL A 209 ( 4.8A) | 1.46A | 5igjA-1k26A:0.0 | 5igjA-1k26A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lfw | PEPV (Lactobacillusdelbrueckii) |
PF01546(Peptidase_M20) | 4 | PRO A 220HIS A 308LEU A 207TYR A 239 | None | 1.20A | 5igjA-1lfwA:0.8 | 5igjA-1lfwA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lqa | TAS PROTEIN (Escherichiacoli) |
PF00248(Aldo_ket_red) | 4 | HIS A 4LEU A 307TYR A 208PHE A 215 | None | 1.27A | 5igjA-1lqaA:0.0 | 5igjA-1lqaA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lwh | 4-ALPHA-GLUCANOTRANSFERASE (Thermotogamaritima) |
PF00128(Alpha-amylase)PF09178(DUF1945) | 4 | PRO A 308HIS A 375LEU A 404PHE A 289 | None | 1.48A | 5igjA-1lwhA:undetectable | 5igjA-1lwhA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m1l | SUPPRESSOR OF FUSED (Homo sapiens) |
PF05076(SUFU) | 4 | PRO A 134HIS A 89LEU A 144PHE A 93 | None | 1.35A | 5igjA-1m1lA:undetectable | 5igjA-1m1lA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mco | IGG1 MCG INTACTANTIBODY (HEAVYCHAIN) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | PRO H 229HIS H 420LEU H 391TYR H 358 | GAL H 435 (-4.8A)NoneNoneNone | 1.06A | 5igjA-1mcoH:undetectable | 5igjA-1mcoH:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nlu | SEDOLISIN (Pseudomonas sp.) |
no annotation | 4 | PRO A 260LEU A 361TYR A 17PHE A 13 | None | 1.43A | 5igjA-1nluA:undetectable | 5igjA-1nluA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1obh | LEUCYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00133(tRNA-synt_1)PF08264(Anticodon_1)PF13603(tRNA-synt_1_2)PF14795(Leucyl-specific) | 4 | PRO A 520HIS A 515LEU A 28TYR A 36 | None | 1.47A | 5igjA-1obhA:undetectable | 5igjA-1obhA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sma | MALTOGENIC AMYLASE (Thermus sp.IM6501) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | PRO A 453LEU A 486TYR A 457PHE A 145 | None | 1.48A | 5igjA-1smaA:3.2 | 5igjA-1smaA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1thg | LIPASE 2 (Galactomycescandidus) |
PF00135(COesterase) | 4 | PRO A 90HIS A 451TYR A 146PHE A 485 | None | 1.46A | 5igjA-1thgA:undetectable | 5igjA-1thgA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 1ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | PRO B 339HIS B 170LEU B 181PHE A 408 | None | 1.45A | 5igjA-1tqyB:undetectable | 5igjA-1tqyB:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vf8 | SECRETORY PROTEIN (Mus musculus) |
PF00704(Glyco_hydro_18) | 4 | PRO A 269HIS A 248LEU A 289TYR A 283 | None | 1.45A | 5igjA-1vf8A:undetectable | 5igjA-1vf8A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x3w | PEPTIDE:N-GLYCANASE (Saccharomycescerevisiae) |
PF03835(Rad4) | 4 | PRO A 244LEU A 202TYR A 211PHE A 261 | None | 1.46A | 5igjA-1x3wA:undetectable | 5igjA-1x3wA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i7t | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR73 KDA SUBUNIT (Homo sapiens) |
PF00753(Lactamase_B)PF07521(RMMBL)PF10996(Beta-Casp) | 4 | PRO A 54HIS A 71LEU A 128PHE A 241 | None ZN A 482 (-3.5A)NoneNone | 1.49A | 5igjA-2i7tA:undetectable | 5igjA-2i7tA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3r | 12-OXOPHYTODIENOATEREDUCTASE 1 (Arabidopsisthaliana) |
PF00724(Oxidored_FMN) | 4 | PRO A 15LEU A 60TYR A 325PHE A 306 | None | 1.37A | 5igjA-2q3rA:undetectable | 5igjA-2q3rA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v79 | DNA REPLICATIONPROTEIN DNAD (Bacillussubtilis) |
no annotation | 4 | PRO A 101LEU A 57TYR A 50PHE A 94 | None | 1.31A | 5igjA-2v79A:undetectable | 5igjA-2v79A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vge | RELA-ASSOCIATEDINHIBITOR (Homo sapiens) |
PF00023(Ank)PF14604(SH3_9) | 4 | PRO A 696HIS A 715LEU A 640TYR A 673 | None | 1.46A | 5igjA-2vgeA:undetectable | 5igjA-2vgeA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsm | HEMAGGLUTININ-NEURAMINIDASE (Nipahhenipavirus) |
PF00423(HN) | 4 | PRO A 535LEU A 222TYR A 454PHE A 466 | NoneNoneIPA A1604 (-4.5A)None | 1.39A | 5igjA-2vsmA:1.8 | 5igjA-2vsmA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wuy | POLYHEDRIN (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF00738(Polyhedrin) | 4 | PRO A 149HIS A 139LEU A 71TYR A 95 | None | 1.48A | 5igjA-2wuyA:undetectable | 5igjA-2wuyA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzr | UNSATURATEDGLUCURONYL HYDROLASE (Streptococcusagalactiae) |
PF07470(Glyco_hydro_88) | 4 | PRO A 257LEU A 340TYR A 381PHE A 73 | None | 1.22A | 5igjA-2zzrA:undetectable | 5igjA-2zzrA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzr | UNSATURATEDGLUCURONYL HYDROLASE (Streptococcusagalactiae) |
PF07470(Glyco_hydro_88) | 4 | PRO A 257LEU A 343TYR A 381PHE A 73 | None | 1.26A | 5igjA-2zzrA:undetectable | 5igjA-2zzrA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b3j | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Rattusnorvegicus) |
PF06325(PrmA) | 4 | PRO A 374LEU A 467TYR A 449PHE A 265 | NoneBEN A1001 (-4.5A)BEN A6001 ( 4.1A)BEN A4001 ( 4.0A) | 1.49A | 5igjA-3b3jA:1.0 | 5igjA-3b3jA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bb6 | UNCHARACTERIZEDPROTEIN YEAR (Escherichiacoli) |
PF09313(DUF1971) | 4 | PRO A 63HIS A 30LEU A 2PHE A 94 | None ZN A 128 (-4.1A)NoneNone | 1.41A | 5igjA-3bb6A:undetectable | 5igjA-3bb6A:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfh | MANDELATE RACEMASE (VibrionalesbacteriumSWAT-3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | PRO A 237HIS A 209LEU A 188PHE A 231 | None | 1.42A | 5igjA-3dfhA:undetectable | 5igjA-3dfhA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9y | ACETOLACTATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | HIS A 352LEU A 568TYR A 579PHE A 578 | NoneTDM A 700 (-3.8A)NoneNone | 1.43A | 5igjA-3e9yA:undetectable | 5igjA-3e9yA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdn | R-OXYNITRILE LYASEISOENZYME 1 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | PRO A 299HIS A 497LEU A 409PHE A 330 | NoneHBX A 530 ( 3.9A)NoneHBX A 530 (-4.0A) | 1.46A | 5igjA-3gdnA:undetectable | 5igjA-3gdnA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjw | 50S RIBOSOMALPROTEIN L7AEPSEUDOURIDINESYNTHASE CBF5 (Pyrococcusfuriosus) |
PF01248(Ribosomal_L7Ae)PF01472(PUA)PF01509(TruB_N)PF08068(DKCLD)PF16198(TruB_C_2) | 4 | PRO C 60LEU A 54TYR A 226PHE A 229 | None | 1.31A | 5igjA-3hjwC:undetectable | 5igjA-3hjwC:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNITA'DNA-DIRECTED RNAPOLYMERASE SUBUNIT B (Sulfolobussolfataricus) |
PF00562(RNA_pol_Rpb2_6)PF00623(RNA_pol_Rpb1_2)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | PRO B1016HIS B 841LEU A 411TYR A 377 | None | 1.12A | 5igjA-3hkzB:undetectable | 5igjA-3hkzB:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ide | CAPSID PROTEIN VP2 (Infectiouspancreaticnecrosis virus) |
PF01766(Birna_VP2) | 4 | PRO A 57LEU A 364TYR A 68PHE A 79 | None | 1.40A | 5igjA-3ideA:undetectable | 5igjA-3ideA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2g | RESINIFERATOXIN-BINDING,PHOSPHOTRIESTERASE-RELATED PROTEIN (Rhodobactersphaeroides) |
PF02126(PTE) | 4 | PRO A 104HIS A 301TYR A 268PHE A 266 | None | 1.48A | 5igjA-3k2gA:undetectable | 5igjA-3k2gA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzq | PUTATIVEUNCHARACTERIZEDPROTEIN VP2116 (Vibrioparahaemolyticus) |
PF13743(Thioredoxin_5) | 4 | PRO A 122HIS A 113LEU A 137TYR A 104 | NoneNoneNonePG6 A 209 (-4.1A) | 1.47A | 5igjA-3kzqA:undetectable | 5igjA-3kzqA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpd | ACIDIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE APRV2 (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | PRO A 3HIS A 282LEU A 50PHE A 272 | None | 1.42A | 5igjA-3lpdA:undetectable | 5igjA-3lpdA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lsc | TRIAZINE HYDROLASE (Paenarthrobacteraurescens) |
PF01979(Amidohydro_1) | 4 | PRO A 299HIS A 236LEU A 115TYR A 67 | NoneNoneNoneAOO A 457 (-4.7A) | 1.46A | 5igjA-3lscA:undetectable | 5igjA-3lscA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ovg | AMIDOHYDROLASE (Mycoplasmasynoviae) |
PF02126(PTE) | 4 | HIS A 214LEU A 169TYR A 105PHE A 104 | ZN A 363 (-3.5A)NoneNoneNone | 1.47A | 5igjA-3ovgA:undetectable | 5igjA-3ovgA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psg | PEPSINOGEN (Sus scrofa) |
PF00026(Asp)PF07966(A1_Propeptide) | 4 | PRO A 5HIS A 53LEU A 38PHE A 15 | None | 1.42A | 5igjA-3psgA:undetectable | 5igjA-3psgA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdq | 4-HYDROXYBUTYRATECOA-TRANSFERASE (Clostridiumaminobutyricum) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | PRO A 184HIS A 31TYR A 66PHE A 77 | None | 1.46A | 5igjA-3qdqA:undetectable | 5igjA-3qdqA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r44 | FATTY ACYL COASYNTHETASE FADD13(FATTY-ACYL-COASYNTHETASE) (Mycobacteriumtuberculosis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | PRO A 229LEU A 141TYR A 72PHE A 71 | None | 1.37A | 5igjA-3r44A:undetectable | 5igjA-3r44A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3red | HYDROXYNITRILE LYASE (Prunus mume) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | PRO A 300HIS A 498LEU A 410PHE A 331 | NoneFAD A 773 (-4.4A)NoneNone | 1.43A | 5igjA-3redA:undetectable | 5igjA-3redA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0j | TYPE III EFFECTORHOPU1 (Pseudomonassyringae groupgenomosp. 3) |
no annotation | 4 | PRO B 239HIS B 141TYR B 78PHE B 66 | None | 1.47A | 5igjA-3u0jB:undetectable | 5igjA-3u0jB:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsc | PROTEIN CYSO (Aeropyrumpernix) |
PF00291(PALP) | 4 | PRO A 96HIS A 234LEU A 29TYR A 51 | None | 1.48A | 5igjA-3vscA:undetectable | 5igjA-3vscA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x43 | O-UREIDO-L-SERINESYNTHASE (Streptomyceslavendulae) |
PF00291(PALP) | 4 | PRO A 291HIS A 217LEU A 239PHE A 226 | PLP A 401 (-4.1A)NoneNoneNone | 1.20A | 5igjA-3x43A:undetectable | 5igjA-3x43A:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4asi | ACETYL-COACARBOXYLASE 1 (Homo sapiens) |
PF01039(Carboxyl_trans) | 4 | HIS A1919LEU A2077TYR A2064PHE A2061 | None | 1.11A | 5igjA-4asiA:undetectable | 5igjA-4asiA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bla | MALTOSE-BINDINGPERIPLASMIC PROTEIN,SUPPRESSOR OF FUSEDHOMOLOG (Escherichiacoli;Homo sapiens) |
PF05076(SUFU)PF12470(SUFU_C)PF13416(SBP_bac_8) | 4 | PRO A 474HIS A 429LEU A 484PHE A 433 | None | 1.41A | 5igjA-4blaA:undetectable | 5igjA-4blaA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bz7 | HISTONE DEACETYLASE8 (Schistosomamansoni) |
PF00850(Hist_deacetyl) | 4 | HIS A 142LEU A 97TYR A 110PHE A 21 | B3N A 700 (-3.7A)NoneNoneNone | 1.46A | 5igjA-4bz7A:undetectable | 5igjA-4bz7A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eo4 | THREONINE--TRNALIGASE,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 4 | PRO A 315HIS A 184LEU A 249PHE A 269 | None ZN A1003 (-3.6A)NoneNone | 1.38A | 5igjA-4eo4A:undetectable | 5igjA-4eo4A:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ezi | UNCHARACTERIZEDPROTEIN (Legionellapneumophila) |
no annotation | 4 | PRO A 222HIS A 327TYR A 157PHE A 251 | NoneNoneNonePEG A 501 (-4.6A) | 1.37A | 5igjA-4eziA:undetectable | 5igjA-4eziA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f99 | CELL DIVISION CYCLE7-RELATED PROTEINKINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | PRO A 554LEU A 421TYR A 415PHE A 379 | None | 1.45A | 5igjA-4f99A:8.3 | 5igjA-4f99A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdg | MINICHROMOSOMEMAINTENANCE PROTEINMCM (Sulfolobussolfataricus) |
no annotation | 4 | PRO B 104LEU B 74TYR B 30PHE B 21 | None | 1.28A | 5igjA-4fdgB:undetectable | 5igjA-4fdgB:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hvl | MEMBRANE-ANCHOREDMYCOSIN MYCP1 (Mycolicibacteriumthermoresistibile) |
PF00082(Peptidase_S8) | 4 | PRO A 289LEU A 278TYR A 339PHE A 335 | None | 1.39A | 5igjA-4hvlA:undetectable | 5igjA-4hvlA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwt | THREONINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 4 | PRO A 619HIS A 497LEU A 552PHE A 572 | None ZN A 801 ( 3.3A)NoneNone | 1.32A | 5igjA-4hwtA:undetectable | 5igjA-4hwtA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifs | FACT COMPLEX SUBUNITSSRP1 (Homo sapiens) |
PF08512(Rtt106) | 4 | PRO A 366LEU A 205TYR A 232PHE A 230 | None | 1.50A | 5igjA-4ifsA:undetectable | 5igjA-4ifsA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jgb | PUTATIVE EXPORTEDPROTEIN (Burkholderiapseudomallei) |
PF13460(NAD_binding_10) | 4 | PRO A 71LEU A 172TYR A 209PHE A 165 | SO4 A 302 (-3.1A)NoneNoneNone | 1.37A | 5igjA-4jgbA:undetectable | 5igjA-4jgbA:24.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kcd | GLUTAMATE RECEPTORIONOTROPIC, NMDA 3A (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | PRO A 205LEU A 108TYR A 252PHE A 141 | NoneNoneNoneGOL A 301 (-4.0A) | 1.34A | 5igjA-4kcdA:undetectable | 5igjA-4kcdA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpg | MEMBRANE-ANCHOREDMYCOSIN MYCP1 (Mycolicibacteriumsmegmatis) |
PF00082(Peptidase_S8) | 4 | PRO A 289LEU A 278TYR A 339PHE A 335 | None | 1.47A | 5igjA-4kpgA:undetectable | 5igjA-4kpgA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4li2 | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 4R-SPONDIN-1 (Homo sapiens;Xenopustropicalis) |
PF13516(LRR_6)PF13855(LRR_8)PF15913(Furin-like_2) | 4 | PRO B 89HIS A 210LEU A 240TYR A 283 | None | 1.39A | 5igjA-4li2B:undetectable | 5igjA-4li2B:13.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1z | MEMBRANE-ANCHOREDMYCOSIN MYCP1 (Mycolicibacteriumsmegmatis) |
PF00082(Peptidase_S8) | 4 | PRO A 289LEU A 278TYR A 339PHE A 335 | None | 1.45A | 5igjA-4m1zA:undetectable | 5igjA-4m1zA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q65 | DIPEPTIDE PERMEASE D (Escherichiacoli) |
PF00854(PTR2) | 4 | PRO A 155LEU A 107TYR A 114PHE A 117 | None | 1.20A | 5igjA-4q65A:undetectable | 5igjA-4q65A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ufs | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 5R-SPONDIN-2 (Homo sapiens) |
PF00560(LRR_1)PF01462(LRRNT)PF13855(LRR_8)PF15913(Furin-like_2) | 4 | PRO B 88HIS A 216LEU A 246TYR A 289 | None | 1.43A | 5igjA-4ufsB:undetectable | 5igjA-4ufsB:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ur8 | KETO-DEOXY-D-GALACTARATE DEHYDRATASE (Agrobacteriumtumefaciens) |
PF00701(DHDPS) | 4 | PRO A 111LEU A 15TYR A 202PHE A 198 | None | 1.37A | 5igjA-4ur8A:undetectable | 5igjA-4ur8A:24.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v20 | CELLOBIOHYDROLASE (Aspergillusfumigatus) |
PF00840(Glyco_hydro_7) | 4 | PRO A 177HIS A 206LEU A 73TYR A 51 | NoneNonePCA A 1 ( 4.5A)None | 1.47A | 5igjA-4v20A:undetectable | 5igjA-4v20A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dld | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Burkholderiavietnamiensis) |
PF02350(Epimerase_2) | 4 | HIS A 247LEU A 48TYR A 274PHE A 277 | UD1 A 502 (-4.0A)NoneUDP A 501 (-4.4A)UDP A 501 (-3.6A) | 1.15A | 5igjA-5dldA:undetectable | 5igjA-5dldA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eo6 | COPROPORPHYRINOGENOXIDASE (Acinetobacterbaumannii) |
PF01218(Coprogen_oxidas) | 4 | PRO A 278HIS A 115LEU A 303TYR A 256 | NoneACT A 400 (-3.1A)NoneNone | 1.36A | 5igjA-5eo6A:undetectable | 5igjA-5eo6A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5feb | SODIUM CHANNELSUBUNIT BETA-2 (Homo sapiens) |
PF07686(V-set) | 4 | PRO A 35HIS A 139LEU A 81TYR A 69 | None | 1.12A | 5igjA-5febA:undetectable | 5igjA-5febA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gz4 | SNAKE VENOMPHOSPHODIESTERASE(PDE) (Naja atra) |
PF01033(Somatomedin_B)PF01223(Endonuclease_NS)PF01663(Phosphodiest) | 4 | PRO A 725LEU A 641TYR A 670PHE A 674 | None | 1.41A | 5igjA-5gz4A:0.3 | 5igjA-5gz4A:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h8k | N-CARBAMOYLPUTRESCINE AMIDOHYDROLASE (Medicagotruncatula) |
PF00795(CN_hydrolase) | 4 | HIS A 206LEU A 45TYR A 119PHE A 143 | None | 1.31A | 5igjA-5h8kA:undetectable | 5igjA-5h8kA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hax | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF08801(Nucleoporin_N) | 4 | PRO A 556LEU A 678TYR A 605PHE A 601 | None | 1.32A | 5igjA-5haxA:3.2 | 5igjA-5haxA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hss | LINALOOLDEHYDRATASE/ISOMERASE (Castellanielladefragrans) |
no annotation | 4 | PRO A 364HIS A 194LEU A 131TYR A 145 | None | 1.41A | 5igjA-5hssA:undetectable | 5igjA-5hssA:22.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5igp | MACROLIDE2'-PHOSPHOTRANSFERASE (Escherichiacoli) |
PF01636(APH) | 5 | PRO A 112HIS A 205LEU A 270TYR A 277PHE A 280 | ERY A 402 ( 4.1A)GDP A 401 (-4.4A)NoneERY A 402 ( 4.5A)ERY A 402 ( 3.6A) | 0.18A | 5igjA-5igpA:48.1 | 5igjA-5igpA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdx | METALLOPEPTIDASE (Pseudomonasaeruginosa) |
PF13402(Peptidase_M60) | 4 | PRO A 838LEU A 860TYR A 811PHE A 628 | None | 1.43A | 5igjA-5kdxA:undetectable | 5igjA-5kdxA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH DEHYDROGENASE[UBIQUINONE] 1SUBUNIT C1,MITOCHONDRIALNADH DEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2 (Bos taurus) |
PF00329(Complex1_30kDa)PF00346(Complex1_49kDa) | 4 | PRO d 52HIS c 9LEU c 21TYR d 64 | None | 1.28A | 5igjA-5lc5d:undetectable | 5igjA-5lc5d:10.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5liy | ALDO-KETO REDUCTASEFAMILY 1 MEMBER B10 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | PRO X 124HIS X 111TYR X 310PHE X 312 | NoneDQP X 402 ( 4.1A)NoneDQP X 402 (-4.9A) | 1.38A | 5igjA-5liyX:undetectable | 5igjA-5liyX:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | PRO A 77HIS A 434TYR A 369PHE A 362 | None | 1.17A | 5igjA-5m8tA:undetectable | 5igjA-5m8tA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mhf | MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE (Mus musculus) |
no annotation | 4 | PRO A 249HIS A 159LEU A 117PHE A 155 | None | 1.28A | 5igjA-5mhfA:1.0 | 5igjA-5mhfA:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thm | ESTERASE-6 (Drosophilamelanogaster) |
PF00135(COesterase) | 4 | PRO A 220HIS A 445LEU A 327TYR A 273 | None7BZ A 601 (-3.8A)NoneNone | 1.10A | 5igjA-5thmA:undetectable | 5igjA-5thmA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uh0 | MEMBRANE-BOUND LYTICMUREINTRANSGLYCOSYLASE F (Yersinia pestis) |
PF00497(SBP_bac_3) | 4 | PRO A 86LEU A 209TYR A 264PHE A 66 | None | 1.30A | 5igjA-5uh0A:undetectable | 5igjA-5uh0A:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujz | SCFV (Homo sapiens) |
PF07686(V-set) | 4 | PRO G 45HIS G 160LEU G 34TYR G 236 | None | 1.40A | 5igjA-5ujzG:undetectable | 5igjA-5ujzG:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ums | FACT COMPLEX SUBUNITSSRP1 (Homo sapiens) |
no annotation | 4 | PRO A 366LEU A 205TYR A 232PHE A 230 | None | 1.48A | 5igjA-5umsA:undetectable | 5igjA-5umsA:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vkq | NO MECHANORECEPTORPOTENTIAL C ISOFORML (Drosophilamelanogaster) |
PF00023(Ank)PF00520(Ion_trans)PF12796(Ank_2)PF13637(Ank_4) | 4 | PRO A1080HIS A1056LEU A1036TYR A1011 | None | 1.49A | 5igjA-5vkqA:undetectable | 5igjA-5vkqA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3v | APOBEC3H (Macacanemestrina) |
no annotation | 4 | PRO B 36LEU B 47TYR B 79PHE B 107 | None | 1.13A | 5igjA-5w3vB:undetectable | 5igjA-5w3vB:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x09 | V-TYPE ATP SYNTHASEALPHA CHAIN,V-TYPEATP SYNTHASE ALPHACHAIN (Pyrococcushorikoshii) |
no annotation | 4 | PRO A 281LEU A 211TYR A 324PHE A 319 | None | 1.30A | 5igjA-5x09A:undetectable | 5igjA-5x09A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xev | XAA-PRODIPEPTIDASE,PEPTIDASE-RELATED PROTEIN (Deinococcusradiodurans) |
no annotation | 4 | PRO A 83LEU A 36TYR A 23PHE A 25 | NoneNoneNone CL A 505 ( 4.8A) | 1.48A | 5igjA-5xevA:undetectable | 5igjA-5xevA:25.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y4u | - (-) |
no annotation | 4 | PRO A 171LEU A 248TYR A 221PHE A 226 | None | 1.17A | 5igjA-5y4uA:undetectable | 5igjA-5y4uA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy0 | CYTOSOLICNIFE-HYDROGENASE,ALPHA SUBUNIT (Thermococcuskodakarensis) |
no annotation | 4 | PRO A 377HIS A 111LEU A 276PHE A 304 | None | 1.40A | 5igjA-5yy0A:undetectable | 5igjA-5yy0A:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bms | PALMITOYLTRANSFERASE (Danio rerio) |
no annotation | 4 | HIS A 142LEU A 137TYR A 155PHE A 158 | ZN A1002 ( 3.1A)NoneNonePLM A1006 (-4.7A) | 1.42A | 5igjA-6bmsA:2.0 | 5igjA-6bmsA:12.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6u | - (-) |
no annotation | 4 | PRO N 100LEU N 26TYR N 68PHE N 65 | None | 1.37A | 5igjA-6c6uN:undetectable | 5igjA-6c6uN:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0y | NUCLEAR CAP-BINDINGPROTEIN SUBUNIT 2 (Homo sapiens) |
no annotation | 4 | HIS A 24LEU A 36TYR A 43PHE A 83 | NoneNoneGTA A 201 (-3.4A)GTA A 201 (-3.7A) | 1.40A | 5igjA-6d0yA:undetectable | 5igjA-6d0yA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6df3 | - (-) |
no annotation | 4 | HIS C 167LEU C 151TYR C 116PHE C 115 | None | 1.22A | 5igjA-6df3C:undetectable | 5igjA-6df3C:undetectable |