SIMILAR PATTERNS OF AMINO ACIDS FOR 5HPW_D_3CJD609_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1d7w | MYELOPEROXIDASE (Homo sapiens) |
PF03098(An_peroxidase) | 4 | GLN A 91HIS A 95ARG C 239GLU C 242 | HEM A 605 ( 3.4A)CYN A1844 (-4.1A)HEM A 605 (-4.3A)HEM A 605 (-2.1A) | 0.34A | 5hpwD-1d7wA:undetectable | 5hpwD-1d7wA:38.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyi | ATP-DEPENDENT HSLPROTEASE ATP-BINDINGSUBUNIT HSLU (Haemophilusinfluenzae) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 15HIS A 16ARG A 69GLU A 12 | None | 1.21A | 5hpwD-1kyiA:0.0 | 5hpwD-1kyiA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofh | ATP-DEPENDENT HSLPROTEASE ATP-BINDINGSUBUNIT HSLU (Haemophilusinfluenzae) |
PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 15HIS A 16ARG A 69GLU A 12 | None | 1.33A | 5hpwD-1ofhA:0.0 | 5hpwD-1ofhA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qvr | CLPB PROTEIN (Thermusthermophilus) |
PF00004(AAA)PF02861(Clp_N)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 142HIS A 145ARG A 162GLU A 166 | None | 1.49A | 5hpwD-1qvrA:0.0 | 5hpwD-1qvrA:21.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gjm | LACTOPEROXIDASE (Bubalus bubalis) |
PF03098(An_peroxidase) | 4 | GLN A 91HIS A 95ARG A 239GLU A 242 | HEM A 605 (-3.4A)SCN A1502 ( 4.8A)HEM A 605 (-4.7A)HEM A 605 ( 2.2A) | 0.53A | 5hpwD-2gjmA:22.1 | 5hpwD-2gjmA:95.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkp | NPH1-1, RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 4 | GLN A 479HIS A 519ARG A 521GLU A 525 | None | 1.49A | 5hpwD-2wkpA:0.0 | 5hpwD-2wkpA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6erc | PEROXINECTIN A (Dictyosteliumdiscoideum) |
no annotation | 4 | GLN A 97HIS A 101ARG A 233GLU A 236 | HEM A 604 (-3.4A)NoneHEM A 604 (-3.1A)HEM A 604 (-2.2A) | 0.63A | 5hpwD-6ercA:39.4 | 5hpwD-6ercA:8.99 |