SIMILAR PATTERNS OF AMINO ACIDS FOR 5HIE_C_P06C801_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f2e | GLUTATHIONES-TRANSFERASE (Sphingomonaspaucimobilis) |
PF00043(GST_C)PF02798(GST_N) | 4 | ILE A 5VAL A 168ASN A 66PHE A 109 | NoneNoneGSH A 210 (-4.1A)None | 0.93A | 5hieC-1f2eA:0.0 | 5hieC-1f2eA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fft | UBIQUINOL OXIDASE (Escherichiacoli) |
PF00510(COX3) | 4 | ILE C 177VAL C 189PHE C 186PHE C 78 | None | 0.96A | 5hieC-1fftC:3.2 | 5hieC-1fftC:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkw | DIAMINOPIMELATEDECARBOXYLASE (Mycobacteriumtuberculosis) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | ILE A 154VAL A 196ILE A 142PHE A 200 | None | 0.98A | 5hieC-1hkwA:0.0 | 5hieC-1hkwA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkw | DIAMINOPIMELATEDECARBOXYLASE (Mycobacteriumtuberculosis) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | VAL A 79ILE A 305ASN A 342PHE A 74 | None | 0.87A | 5hieC-1hkwA:0.0 | 5hieC-1hkwA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8q | HYALURONATE LYASE (Streptococcusagalactiae) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 4 | VAL A 409PHE A 408ILE A 365PHE A 415 | None | 0.85A | 5hieC-1i8qA:0.3 | 5hieC-1i8qA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kt1 | FK506-BINDINGPROTEIN FKBP51 (Saimiriboliviensis) |
PF00254(FKBP_C)PF00515(TPR_1)PF13181(TPR_8) | 4 | ILE A 242VAL A 190ILE A 198CYH A 215 | None | 0.97A | 5hieC-1kt1A:0.0 | 5hieC-1kt1A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l6r | HYPOTHETICAL PROTEINTA0175 (Thermoplasmaacidophilum) |
PF08282(Hydrolase_3) | 4 | VAL A 49PHE A 71ILE A 77ASN A 146 | None | 1.00A | 5hieC-1l6rA:undetectable | 5hieC-1l6rA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n3y | INTEGRIN ALPHA-X (Homo sapiens) |
PF00092(VWA) | 4 | ILE A 159VAL A 269ILE A 306PHE A 300 | None | 0.98A | 5hieC-1n3yA:undetectable | 5hieC-1n3yA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1om9 | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA1 (Homo sapiens) |
PF02883(Alpha_adaptinC2) | 4 | VAL A 545ILE A 592ASN A 622PHE A 560 | None | 0.94A | 5hieC-1om9A:0.0 | 5hieC-1om9A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qb4 | PHOSPHOENOLPYRUVATECARBOXYLASE (Escherichiacoli) |
PF00311(PEPcase) | 4 | ILE A 263VAL A 486ILE A 461ASN A 256 | None | 0.98A | 5hieC-1qb4A:1.5 | 5hieC-1qb4A:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhm | PYRUVATEFORMATE-LYASE (Escherichiacoli) |
PF02901(PFL-like) | 4 | ILE A1392VAL A1349ILE A1373PHE A1354 | None | 1.00A | 5hieC-1qhmA:0.0 | 5hieC-1qhmA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rz2 | CONSERVEDHYPOTHETICAL PROTEINBA4783 (Bacillusanthracis) |
PF04203(Sortase) | 4 | ILE A 52VAL A 128ILE A 96PHE A 172 | None | 0.83A | 5hieC-1rz2A:undetectable | 5hieC-1rz2A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s5j | DNA POLYMERASE I (Sulfolobussolfataricus) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | ILE A 416ILE A 230ASN A 378PHE A 317 | None | 0.94A | 5hieC-1s5jA:undetectable | 5hieC-1s5jA:16.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5k | MICROTUBULE-ASSOCIATED PROTEIN, RP/EBFAMILY, MEMBER 1 (Mus musculus) |
PF00307(CH) | 4 | ILE A 28VAL A 54ASN A 18PHE A 56 | None | 0.91A | 5hieC-1v5kA:undetectable | 5hieC-1v5kA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vka | MICROTUBULE-ASSOCIATED PROTEIN RP/EBFAMILY MEMBER 1 (Homo sapiens) |
PF00307(CH) | 4 | ILE A 35VAL A 61ASN A 25PHE A 63 | None | 0.79A | 5hieC-1vkaA:undetectable | 5hieC-1vkaA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wpw | 3-ISOPROPYLMALATEDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00180(Iso_dh) | 4 | ILE A 61VAL A 277PHE A 252ILE A 67 | None | 0.83A | 5hieC-1wpwA:undetectable | 5hieC-1wpwA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyo | MICROTUBULE-ASSOCIATED PROTEIN RP/EBFAMILY MEMBER 3 (Homo sapiens) |
PF00307(CH) | 4 | ILE A 42VAL A 68ASN A 32PHE A 70 | None | 0.71A | 5hieC-1wyoA:undetectable | 5hieC-1wyoA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 4 | VAL A 282PHE A 319ASN A 334PHE A 310 | None | 0.99A | 5hieC-1xzwA:undetectable | 5hieC-1xzwA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | VAL A 773ILE A 666ASN A 624PHE A 581 | None | 0.99A | 5hieC-1ygpA:undetectable | 5hieC-1ygpA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2csu | 457AA LONGHYPOTHETICAL PROTEIN (Pyrococcushorikoshii) |
PF13380(CoA_binding_2)PF13607(Succ_CoA_lig) | 4 | VAL A 89ILE A 14CYH A 129ASN A 140 | None | 0.96A | 5hieC-2csuA:undetectable | 5hieC-2csuA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d8x | PROTEIN PINCH (Homo sapiens) |
PF00412(LIM) | 4 | ILE A 16VAL A 40PHE A 32ILE A 20 | None | 0.93A | 5hieC-2d8xA:undetectable | 5hieC-2d8xA:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dby | GTP-BINDING PROTEIN (Thermusthermophilus) |
PF01926(MMR_HSR1)PF06071(YchF-GTPase_C) | 4 | VAL A 4ILE A 76ASN A 19PHE A 73 | None | 0.98A | 5hieC-2dbyA:undetectable | 5hieC-2dbyA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dt7 | SPLICING FACTOR 3SUBUNIT 1 (Homo sapiens) |
PF01805(Surp) | 4 | ILE B 153VAL B 166ILE B 159PHE B 162 | None | 0.96A | 5hieC-2dt7B:undetectable | 5hieC-2dt7B:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ete | OXALATE OXIDASE 1 (Hordeum vulgare) |
PF00190(Cupin_1) | 4 | VAL A 106PHE A 138ASN A 154PHE A 129 | None | 0.94A | 5hieC-2eteA:undetectable | 5hieC-2eteA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpr | HISTIDINEBIOSYNTHESISBIFUNCTIONAL PROTEINHISB (Escherichiacoli) |
PF08645(PNK3P) | 4 | ILE A 93VAL A 37ILE A 9ASN A 75 | None | 0.84A | 5hieC-2fprA:undetectable | 5hieC-2fprA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gp6 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Mycobacteriumtuberculosis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ILE A 357ILE A 261CYH A 194ASN A 400 | None | 0.89A | 5hieC-2gp6A:undetectable | 5hieC-2gp6A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hxd | DCTP DEAMINASE,DUMP-FORMING (Methanocaldococcusjannaschii) |
PF00692(dUTPase) | 4 | ILE A 161VAL A 12ILE A 104PHE A 22 | None | 0.98A | 5hieC-2hxdA:undetectable | 5hieC-2hxdA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j4g | HYALURONOGLUCOSAMINIDASE (Bacteroidesthetaiotaomicron) |
PF02838(Glyco_hydro_20b)PF07555(NAGidase) | 4 | ILE A 244VAL A 342PHE A 136CYH A 278 | NoneNB1 A1590 ( 4.9A)NoneNB1 A1590 (-3.4A) | 0.94A | 5hieC-2j4gA:undetectable | 5hieC-2j4gA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j86 | PROTEINSERINE-THREONINEPHOSPHATASE (Synechococcuselongatus) |
PF13672(PP2C_2) | 4 | ILE A 175VAL A 236PHE A 30ILE A 103 | None | 0.94A | 5hieC-2j86A:undetectable | 5hieC-2j86A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kk4 | UNCHARACTERIZEDPROTEIN AF_2094 (Archaeoglobusfulgidus) |
no annotation | 4 | VAL A 33PHE A 37ILE A 22PHE A 18 | None | 0.97A | 5hieC-2kk4A:undetectable | 5hieC-2kk4A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oqz | SORTASE B (Bacillusanthracis) |
PF04203(Sortase) | 4 | ILE A 52VAL A 128ILE A 96PHE A 172 | None | 0.84A | 5hieC-2oqzA:undetectable | 5hieC-2oqzA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5m | ARGININE REPRESSOR (Bacillussubtilis) |
PF02863(Arg_repressor_C) | 4 | ILE A 131PHE A 84ILE A 87CYH A 123 | None | 0.94A | 5hieC-2p5mA:undetectable | 5hieC-2p5mA:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg0 | ACYL-COADEHYDROGENASE (Geobacilluskaustophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | ILE A 362VAL A 308ILE A 254PHE A 304 | None | 0.96A | 5hieC-2pg0A:undetectable | 5hieC-2pg0A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ppv | UNCHARACTERIZEDPROTEIN (Staphylococcusepidermidis) |
PF01933(UPF0052) | 4 | ILE A 45VAL A 114ILE A 61ASN A 99 | None | 0.96A | 5hieC-2ppvA:undetectable | 5hieC-2ppvA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0t | PUTATIVEGAMMA-CARBOXYMUCONOLACTONE DECARBOXYLASESUBUNIT (Paraburkholderiaxenovorans) |
PF02627(CMD) | 4 | ILE A 83PHE A 190ILE A 63PHE A 195 | None | 0.84A | 5hieC-2q0tA:undetectable | 5hieC-2q0tA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfr | PURPLE ACIDPHOSPHATASE (Phaseolusvulgaris) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 4 | VAL A 283PHE A 320ASN A 335PHE A 311 | None | 0.96A | 5hieC-2qfrA:undetectable | 5hieC-2qfrA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgy | ENOLASE FROM THEENVIRONMENTAL GENOMESHOTGUN SEQUENCINGOF THE SARGASSO SEA (-) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ILE A 284VAL A 247ILE A 295CYH A 316 | None | 0.87A | 5hieC-2qgyA:undetectable | 5hieC-2qgyA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2quq | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITB (Saccharomycescerevisiae) |
PF16846(Cep3) | 4 | VAL A 431PHE A 415ASN A 67PHE A 469 | None | 0.87A | 5hieC-2quqA:2.7 | 5hieC-2quqA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r8u | MICROTUBULE-ASSOCIATED PROTEIN RP/EBFAMILY MEMBER 1 (Homo sapiens) |
PF00307(CH) | 4 | ILE A 35VAL A 61ASN A 25PHE A 63 | None | 0.81A | 5hieC-2r8uA:undetectable | 5hieC-2r8uA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vo9 | L-ALANYL-D-GLUTAMATEPEPTIDASE (Listeria phageA500) |
PF13539(Peptidase_M15_4) | 4 | ILE A 41ILE A 9CYH A 89ASN A 93 | None | 0.97A | 5hieC-2vo9A:undetectable | 5hieC-2vo9A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w37 | ORNITHINECARBAMOYLTRANSFERASE, CATABOLIC (Lactobacillushilgardii) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | ILE A 205PHE A 197ILE A 219PHE A 165 | None | 0.85A | 5hieC-2w37A:undetectable | 5hieC-2w37A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w61 | GLYCOLIPID-ANCHOREDSURFACE PROTEIN 2 (Saccharomycescerevisiae) |
PF03198(Glyco_hydro_72)PF07983(X8) | 4 | ILE A 209VAL A 230PHE A 229ILE A 194 | None | 1.00A | 5hieC-2w61A:undetectable | 5hieC-2w61A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wba | TRYPANOTHIONEREDUCTASE (Trypanosomabrucei) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | VAL A 268ILE A 169ASN A 223PHE A 270 | NoneNoneNDP A1496 (-4.0A)None | 0.80A | 5hieC-2wbaA:undetectable | 5hieC-2wbaA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yps | SORTING NEXIN-3 (Homo sapiens) |
PF00787(PX) | 4 | VAL A 67PHE A 144ILE A 126ASN A 56 | None | 0.98A | 5hieC-2ypsA:undetectable | 5hieC-2ypsA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9i | HOMOCITRATE SYNTHASE (Thermusthermophilus) |
PF00682(HMGL-like) | 4 | ILE A 204VAL A 269ILE A 222PHE A 17 | None | 0.93A | 5hieC-3a9iA:undetectable | 5hieC-3a9iA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNITMEMBRANE-BOUNDHYDROGENASE SMALLSUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ILE B 252VAL A 262PHE A 261PHE A 224 | SF4 B 309 ( 4.1A)NoneNoneNone | 0.99A | 5hieC-3ayxB:undetectable | 5hieC-3ayxB:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bpt | 3-HYDROXYISOBUTYRYL-COA HYDROLASE (Homo sapiens) |
PF16113(ECH_2) | 4 | ILE A 280PHE A 175ILE A 309ASN A 300 | None | 0.93A | 5hieC-3bptA:undetectable | 5hieC-3bptA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c3v | ARACHIN ARAH3ISOFORM (Arachishypogaea) |
PF00190(Cupin_1) | 4 | ILE A 21VAL A 467ASN A 184PHE A 469 | None | 0.99A | 5hieC-3c3vA:0.8 | 5hieC-3c3vA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c6q | SUGAR ABCTRANSPORTER,PERIPLASMICSUGAR-BINDINGPROTEIN (Thermotogamaritima) |
no annotation | 4 | VAL B 126PHE B 186ASN B 105PHE B 145 | None | 0.98A | 5hieC-3c6qB:undetectable | 5hieC-3c6qB:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3chl | ALPHA-14 GIARDIN (Giardiaintestinalis) |
PF00191(Annexin) | 4 | ILE A 111VAL A 253ILE A 268PHE A 249 | None | 0.93A | 5hieC-3chlA:undetectable | 5hieC-3chlA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dcp | HISTIDINOL-PHOSPHATASE (Listeriamonocytogenes) |
PF02811(PHP)PF13263(PHP_C) | 4 | VAL A 243ILE A 182CYH A 233PHE A 223 | None | 0.92A | 5hieC-3dcpA:undetectable | 5hieC-3dcpA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3enh | UNCHARACTERIZEDPROTEIN MJ0187 (Methanocaldococcusjannaschii) |
PF08617(CGI-121) | 4 | VAL C 138ILE C 114CYH C 87PHE C 126 | None | 0.96A | 5hieC-3enhC:undetectable | 5hieC-3enhC:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 4 | VAL A 229ILE A 283CYH A 259PHE A 222 | None | 0.92A | 5hieC-3eqnA:undetectable | 5hieC-3eqnA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5k | PEPTIDE DEFORMYLASE,MITOCHONDRIAL (Homo sapiens) |
PF01327(Pep_deformylase) | 4 | VAL A 102ILE A 154CYH A 164PHE A 127 | None | 0.90A | 5hieC-3g5kA:undetectable | 5hieC-3g5kA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h11 | CASP8 AND FADD-LIKEAPOPTOSIS REGULATOR (Homo sapiens) |
PF00656(Peptidase_C14) | 4 | ILE A 260VAL A 309PHE A 355PHE A 271 | None | 0.99A | 5hieC-3h11A:undetectable | 5hieC-3h11A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hnp | OXIDOREDUCTASE (Bacillus cereus) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | ILE A 86VAL A 30ILE A 66PHE A 7 | None | 0.75A | 5hieC-3hnpA:undetectable | 5hieC-3hnpA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i23 | OXIDOREDUCTASE,GFO/IDH/MOCA FAMILY (Enterococcusfaecalis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | ILE A 86VAL A 30ILE A 66PHE A 7 | None | 0.77A | 5hieC-3i23A:undetectable | 5hieC-3i23A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ivu | HOMOCITRATESYNTHASE,MITOCHONDRIAL (Schizosaccharomycespombe) |
PF00682(HMGL-like) | 4 | ILE A 233VAL A 298ILE A 251PHE A 48 | None | 0.95A | 5hieC-3ivuA:undetectable | 5hieC-3ivuA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jar | MICROTUBULE-ASSOCIATED PROTEIN RP/EBFAMILY MEMBER 3 (Homo sapiens) |
no annotation | 4 | ILE N 35VAL N 61ASN N 25PHE N 63 | None | 0.83A | 5hieC-3jarN:undetectable | 5hieC-3jarN:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kt4 | PKHD-TYPEHYDROXYLASE TPA1 (Saccharomycescerevisiae) |
PF10637(Ofd1_CTDD)PF13661(2OG-FeII_Oxy_4) | 4 | ILE A 241VAL A 132ILE A 168PHE A 128 | None | 0.80A | 5hieC-3kt4A:undetectable | 5hieC-3kt4A:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lg6 | PUTATIVE GLUTATHIONETRANSFERASE (Coccidioidesimmitis) |
PF13409(GST_N_2)PF14497(GST_C_3) | 4 | VAL A 204PHE A 168ILE A 174ASN A 117 | None | 0.96A | 5hieC-3lg6A:undetectable | 5hieC-3lg6A:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nm1 | THIAMINEBIOSYNTHETICBIFUNCTIONAL ENZYME ([Candida]glabrata) |
PF02110(HK)PF02581(TMP-TENI) | 4 | ILE A 257VAL A 412ILE A 476PHE A 486 | None | 0.75A | 5hieC-3nm1A:undetectable | 5hieC-3nm1A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o5d | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEFKBP5 (Homo sapiens) |
PF00254(FKBP_C) | 4 | ILE A 122VAL A 55CYH A 107PHE A 79 | None | 0.98A | 5hieC-3o5dA:undetectable | 5hieC-3o5dA:22.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3omv | RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | ILE A 355ILE A 419CYH A 424PHE A 487 | SM5 A 1 (-4.3A)SM5 A 1 ( 4.3A)SM5 A 1 ( 4.4A)None | 0.69A | 5hieC-3omvA:34.8 | 5hieC-3omvA:77.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3omv | RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | ILE A 355PHE A 408ILE A 419ASN A 472 | SM5 A 1 (-4.3A)NoneSM5 A 1 ( 4.3A)SM5 A 1 (-3.9A) | 0.70A | 5hieC-3omvA:34.8 | 5hieC-3omvA:77.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3omv | RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | ILE A 355PHE A 408ILE A 419CYH A 424 | SM5 A 1 (-4.3A)NoneSM5 A 1 ( 4.3A)SM5 A 1 ( 4.4A) | 0.46A | 5hieC-3omvA:34.8 | 5hieC-3omvA:77.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3omv | RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | VAL A 396PHE A 408ILE A 419ASN A 472 | NoneNoneSM5 A 1 ( 4.3A)SM5 A 1 (-3.9A) | 0.98A | 5hieC-3omvA:34.8 | 5hieC-3omvA:77.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opu | SPAP (Streptococcusmutans) |
PF16364(Antigen_C) | 4 | ILE A1364VAL A1445ILE A1368PHE A1441 | None | 0.97A | 5hieC-3opuA:undetectable | 5hieC-3opuA:20.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ppz | SERINE/THREONINE-PROTEIN KINASE CTR1 (Arabidopsisthaliana) |
PF07714(Pkinase_Tyr) | 4 | ILE A 557PHE A 611ILE A 623PHE A 695 | STU A 1 (-4.1A)NoneNoneNone | 1.00A | 5hieC-3ppzA:28.1 | 5hieC-3ppzA:38.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr3 | ENDOGLUCANASE EG-II (Trichodermareesei) |
PF00150(Cellulase) | 4 | VAL A 290PHE A 59ILE A 9ASN A 105 | None | 0.93A | 5hieC-3qr3A:undetectable | 5hieC-3qr3A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rip | GAMMA-TUBULINCOMPLEX COMPONENT 4 (Homo sapiens) |
PF04130(Spc97_Spc98) | 4 | VAL A 487ILE A 585ASN A 651PHE A 579 | NoneNoneNoneGOL A 679 ( 4.3A) | 0.86A | 5hieC-3ripA:undetectable | 5hieC-3ripA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpw | ABC TRANSPORTER (Rhodopseudomonaspalustris) |
PF13416(SBP_bac_8) | 4 | PHE A 336ILE A 196ASN A 256PHE A 177 | None | 0.97A | 5hieC-3rpwA:undetectable | 5hieC-3rpwA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1s | RESTRICTIONENDONUCLEASE BPUSI (Bacilluspumilus) |
PF02384(N6_Mtase)PF15516(BpuSI_N) | 4 | VAL A 48ILE A 163ASN A 113PHE A 61 | None | 0.87A | 5hieC-3s1sA:undetectable | 5hieC-3s1sA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u50 | TELOMERASE-ASSOCIATED PROTEIN 82 (Tetrahymenathermophila) |
PF08646(Rep_fac-A_C) | 4 | ILE C 513VAL C 591ILE C 520PHE C 653 | None | 0.93A | 5hieC-3u50C:undetectable | 5hieC-3u50C:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgf | MALTO-OLIGOSYLTREHALOSE TREHALOHYDROLASE (Sulfolobussolfataricus) |
PF00128(Alpha-amylase)PF09071(Alpha-amyl_C) | 4 | VAL A 246ILE A 138ASN A 191PHE A 249 | NoneNoneGLC A 604 ( 4.5A)None | 0.89A | 5hieC-3vgfA:undetectable | 5hieC-3vgfA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpz | GLUCOKINASE (Pseudoalteromonassp. AS-131) |
PF02685(Glucokinase) | 4 | ILE A 11VAL A 84ILE A 16CYH A 324 | None | 0.96A | 5hieC-3vpzA:undetectable | 5hieC-3vpzA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdr | ALCOHOLDEHYDROGENASE DOMAINOF THE BIFUNCTIONALACETALDEHYDEDEHYDROGENASE (Parageobacillusthermoglucosidasius) |
PF00465(Fe-ADH) | 4 | ILE A 728VAL A 824ILE A 750PHE A 740 | None | 0.74A | 5hieC-3zdrA:undetectable | 5hieC-3zdrA:24.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zkb | DNA GYRASE SUBUNIT B (Mycobacteriumtuberculosis) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | ILE A 308VAL A 387ILE A 358PHE A 383 | None | 0.99A | 5hieC-3zkbA:undetectable | 5hieC-3zkbA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zth | STU0660 (Streptococcusthermophilus) |
PF16813(Cas_St_Csn2) | 4 | ILE A 246VAL A 202PHE A 234PHE A 237 | None | 0.95A | 5hieC-3zthA:undetectable | 5hieC-3zthA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5p | PROTEIN MXIA (Shigellaflexneri) |
PF00771(FHIPEP) | 4 | ILE A 542PHE A 643ILE A 666CYH A 580 | NoneMLY A 641 ( 4.5A)NoneNone | 0.99A | 5hieC-4a5pA:undetectable | 5hieC-4a5pA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 4 | ILE A 238VAL A 109ILE A 199PHE A 106 | None | 0.98A | 5hieC-4ainA:undetectable | 5hieC-4ainA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aoa | BETA-PHENYLALANINEAMINOTRANSFERASE (Variovoraxparadoxus) |
PF00202(Aminotran_3) | 4 | VAL A 401ILE A 412ASN A 344PHE A 351 | None | 0.93A | 5hieC-4aoaA:undetectable | 5hieC-4aoaA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ars | HISTIDINE ACIDPHOSPHATASE (Hafnia alvei) |
PF00328(His_Phos_2) | 4 | ILE A 15VAL A 402ILE A 313ASN A 298 | None | 1.00A | 5hieC-4arsA:undetectable | 5hieC-4arsA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7p | RALF (Legionellapneumophila) |
PF01369(Sec7) | 4 | ILE A 36VAL A 58ILE A 24PHE A 76 | None | 0.91A | 5hieC-4c7pA:undetectable | 5hieC-4c7pA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4czx | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3 (Neurosporacrassa) |
no annotation | 5 | ILE A 83VAL B 626PHE B 625ASN A 34PHE A 59 | None | 1.47A | 5hieC-4czxA:undetectable | 5hieC-4czxA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fva | 5'-TYROSYL-DNAPHOSPHODIESTERASE (Caenorhabditiselegans) |
PF03372(Exo_endo_phos) | 4 | VAL A 122ILE A 189ASN A 261PHE A 267 | None | 0.71A | 5hieC-4fvaA:undetectable | 5hieC-4fvaA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzy | EXODEOXYRIBONUCLEASE10 (Escherichiacoli) |
PF00929(RNase_T) | 4 | ILE A 142VAL A 88ILE A 5PHE A 84 | None | 0.92A | 5hieC-4fzyA:undetectable | 5hieC-4fzyA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gew | 5'-TYROSYL-DNAPHOSPHODIESTERASE (Caenorhabditiselegans) |
PF03372(Exo_endo_phos)PF14555(UBA_4) | 4 | VAL A 122ILE A 189ASN A 261PHE A 267 | None | 0.72A | 5hieC-4gewA:undetectable | 5hieC-4gewA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6k | AMIDOHYDROLASEFAMILY PROTEIN (Acinetobacterbaumannii) |
PF04909(Amidohydro_2) | 4 | ILE A 248ILE A 222ASN A 210PHE A 217 | None | 0.98A | 5hieC-4i6kA:undetectable | 5hieC-4i6kA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i9y | E3 SUMO-PROTEINLIGASE RANBP2 (Homo sapiens) |
PF00160(Pro_isomerase) | 4 | ILE A 67VAL A 139ILE A 156CYH A 40 | None | 1.00A | 5hieC-4i9yA:undetectable | 5hieC-4i9yA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j1y | COMPLEMENT C1SSUBCOMPONENT (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 4 | ILE A 548VAL A 492ILE A 446PHE A 454 | None | 0.96A | 5hieC-4j1yA:0.4 | 5hieC-4j1yA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jb3 | HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacteroidesthetaiotaomicron) |
PF13419(HAD_2) | 4 | ILE A 26VAL A 114PHE A 113PHE A 84 | None | 0.98A | 5hieC-4jb3A:undetectable | 5hieC-4jb3A:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | ILE A 318VAL A 516ILE A 502ASN A 275PHE A 580 | NoneNoneNoneEDO A 721 ( 4.4A)None | 1.45A | 5hieC-4jclA:undetectable | 5hieC-4jclA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqt | PUTATIVE GLYCOSYLHYDROLASE (Bacteroidesthetaiotaomicron) |
PF06439(DUF1080) | 4 | ILE A 156ILE A 182ASN A 171PHE A 108 | EDO A 505 ( 4.4A)NoneNoneNone | 0.98A | 5hieC-4jqtA:undetectable | 5hieC-4jqtA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7g | 3-HYDROXYPROLINEDEHYDRATSE (Agrobacteriumvitis) |
PF05544(Pro_racemase) | 4 | ILE B 273VAL B 244CYH B 291PHE B 174 | None | 0.87A | 5hieC-4k7gB:0.4 | 5hieC-4k7gB:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpp | PUTATIVEUNCHARACTERIZEDPROTEIN (Archaeoglobusfulgidus) |
PF01699(Na_Ca_ex) | 4 | ILE A 13VAL A 81ILE A 220PHE A 227 | None | 0.97A | 5hieC-4kppA:undetectable | 5hieC-4kppA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqn | D-HYDANTOINASE (Bacillus sp.AR9) |
PF01979(Amidohydro_1) | 4 | ILE A 348VAL A 438ASN A 416PHE A 83 | ILE A 348 ( 0.4A)VAL A 438 ( 0.6A)ASN A 416 ( 0.6A)PHE A 83 ( 1.3A) | 0.96A | 5hieC-4kqnA:undetectable | 5hieC-4kqnA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ksf | MALONYL-COADECARBOXYLASE (Agrobacteriumvitis) |
PF05292(MCD)PF17408(MCD_N) | 4 | ILE A 197VAL A 286ILE A 266PHE A 215 | None | 0.97A | 5hieC-4ksfA:undetectable | 5hieC-4ksfA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m64 | MELIBIOSE CARRIERPROTEIN (Salmonellaenterica) |
PF13347(MFS_2) | 4 | ILE A 250VAL A 390ASN A 244PHE A 386 | None | 0.98A | 5hieC-4m64A:undetectable | 5hieC-4m64A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mix | PUTATIVEINSECTICIDAL TOXIN (Photorhabdusasymbiotica) |
PF04488(Gly_transf_sug) | 4 | ILE A2204VAL A2223ILE A2226PHE A2218 | None | 0.91A | 5hieC-4mixA:undetectable | 5hieC-4mixA:21.91 |