SIMILAR PATTERNS OF AMINO ACIDS FOR 5HIE_C_P06C801_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f2e GLUTATHIONE
S-TRANSFERASE


(Sphingomonas
paucimobilis)
PF00043
(GST_C)
PF02798
(GST_N)
4 ILE A   5
VAL A 168
ASN A  66
PHE A 109
None
None
GSH  A 210 (-4.1A)
None
0.93A 5hieC-1f2eA:
0.0
5hieC-1f2eA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fft UBIQUINOL OXIDASE

(Escherichia
coli)
PF00510
(COX3)
4 ILE C 177
VAL C 189
PHE C 186
PHE C  78
None
0.96A 5hieC-1fftC:
3.2
5hieC-1fftC:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE


(Mycobacterium
tuberculosis)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
4 ILE A 154
VAL A 196
ILE A 142
PHE A 200
None
0.98A 5hieC-1hkwA:
0.0
5hieC-1hkwA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE


(Mycobacterium
tuberculosis)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
4 VAL A  79
ILE A 305
ASN A 342
PHE A  74
None
0.87A 5hieC-1hkwA:
0.0
5hieC-1hkwA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae)
PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N)
4 VAL A 409
PHE A 408
ILE A 365
PHE A 415
None
0.85A 5hieC-1i8qA:
0.3
5hieC-1i8qA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kt1 FK506-BINDING
PROTEIN FKBP51


(Saimiri
boliviensis)
PF00254
(FKBP_C)
PF00515
(TPR_1)
PF13181
(TPR_8)
4 ILE A 242
VAL A 190
ILE A 198
CYH A 215
None
0.97A 5hieC-1kt1A:
0.0
5hieC-1kt1A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l6r HYPOTHETICAL PROTEIN
TA0175


(Thermoplasma
acidophilum)
PF08282
(Hydrolase_3)
4 VAL A  49
PHE A  71
ILE A  77
ASN A 146
None
1.00A 5hieC-1l6rA:
undetectable
5hieC-1l6rA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n3y INTEGRIN ALPHA-X

(Homo sapiens)
PF00092
(VWA)
4 ILE A 159
VAL A 269
ILE A 306
PHE A 300
None
0.98A 5hieC-1n3yA:
undetectable
5hieC-1n3yA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1


(Homo sapiens)
PF02883
(Alpha_adaptinC2)
4 VAL A 545
ILE A 592
ASN A 622
PHE A 560
None
0.94A 5hieC-1om9A:
0.0
5hieC-1om9A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb4 PHOSPHOENOLPYRUVATE
CARBOXYLASE


(Escherichia
coli)
PF00311
(PEPcase)
4 ILE A 263
VAL A 486
ILE A 461
ASN A 256
None
0.98A 5hieC-1qb4A:
1.5
5hieC-1qb4A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhm PYRUVATE
FORMATE-LYASE


(Escherichia
coli)
PF02901
(PFL-like)
4 ILE A1392
VAL A1349
ILE A1373
PHE A1354
None
1.00A 5hieC-1qhmA:
0.0
5hieC-1qhmA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783


(Bacillus
anthracis)
PF04203
(Sortase)
4 ILE A  52
VAL A 128
ILE A  96
PHE A 172
None
0.83A 5hieC-1rz2A:
undetectable
5hieC-1rz2A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5j DNA POLYMERASE I

(Sulfolobus
solfataricus)
PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
4 ILE A 416
ILE A 230
ASN A 378
PHE A 317
None
0.94A 5hieC-1s5jA:
undetectable
5hieC-1s5jA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5k MICROTUBULE-ASSOCIAT
ED PROTEIN, RP/EB
FAMILY, MEMBER 1


(Mus musculus)
PF00307
(CH)
4 ILE A  28
VAL A  54
ASN A  18
PHE A  56
None
0.91A 5hieC-1v5kA:
undetectable
5hieC-1v5kA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vka MICROTUBULE-ASSOCIAT
ED PROTEIN RP/EB
FAMILY MEMBER 1


(Homo sapiens)
PF00307
(CH)
4 ILE A  35
VAL A  61
ASN A  25
PHE A  63
None
0.79A 5hieC-1vkaA:
undetectable
5hieC-1vkaA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wpw 3-ISOPROPYLMALATE
DEHYDROGENASE


(Sulfurisphaera
tokodaii)
PF00180
(Iso_dh)
4 ILE A  61
VAL A 277
PHE A 252
ILE A  67
None
0.83A 5hieC-1wpwA:
undetectable
5hieC-1wpwA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyo MICROTUBULE-ASSOCIAT
ED PROTEIN RP/EB
FAMILY MEMBER 3


(Homo sapiens)
PF00307
(CH)
4 ILE A  42
VAL A  68
ASN A  32
PHE A  70
None
0.71A 5hieC-1wyoA:
undetectable
5hieC-1wyoA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzw PURPLE ACID
PHOSPHATASE


(Ipomoea batatas)
PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N)
4 VAL A 282
PHE A 319
ASN A 334
PHE A 310
None
0.99A 5hieC-1xzwA:
undetectable
5hieC-1xzwA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE


(Saccharomyces
cerevisiae)
PF00343
(Phosphorylase)
4 VAL A 773
ILE A 666
ASN A 624
PHE A 581
None
0.99A 5hieC-1ygpA:
undetectable
5hieC-1ygpA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csu 457AA LONG
HYPOTHETICAL PROTEIN


(Pyrococcus
horikoshii)
PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig)
4 VAL A  89
ILE A  14
CYH A 129
ASN A 140
None
0.96A 5hieC-2csuA:
undetectable
5hieC-2csuA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d8x PROTEIN PINCH

(Homo sapiens)
PF00412
(LIM)
4 ILE A  16
VAL A  40
PHE A  32
ILE A  20
None
0.93A 5hieC-2d8xA:
undetectable
5hieC-2d8xA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dby GTP-BINDING PROTEIN

(Thermus
thermophilus)
PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C)
4 VAL A   4
ILE A  76
ASN A  19
PHE A  73
None
0.98A 5hieC-2dbyA:
undetectable
5hieC-2dbyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dt7 SPLICING FACTOR 3
SUBUNIT 1


(Homo sapiens)
PF01805
(Surp)
4 ILE B 153
VAL B 166
ILE B 159
PHE B 162
None
0.96A 5hieC-2dt7B:
undetectable
5hieC-2dt7B:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ete OXALATE OXIDASE 1

(Hordeum vulgare)
PF00190
(Cupin_1)
4 VAL A 106
PHE A 138
ASN A 154
PHE A 129
None
0.94A 5hieC-2eteA:
undetectable
5hieC-2eteA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fpr HISTIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
HISB


(Escherichia
coli)
PF08645
(PNK3P)
4 ILE A  93
VAL A  37
ILE A   9
ASN A  75
None
0.84A 5hieC-2fprA:
undetectable
5hieC-2fprA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2


(Mycobacterium
tuberculosis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
4 ILE A 357
ILE A 261
CYH A 194
ASN A 400
None
0.89A 5hieC-2gp6A:
undetectable
5hieC-2gp6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxd DCTP DEAMINASE,
DUMP-FORMING


(Methanocaldococcus
jannaschii)
PF00692
(dUTPase)
4 ILE A 161
VAL A  12
ILE A 104
PHE A  22
None
0.98A 5hieC-2hxdA:
undetectable
5hieC-2hxdA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4g HYALURONOGLUCOSAMINI
DASE


(Bacteroides
thetaiotaomicron)
PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase)
4 ILE A 244
VAL A 342
PHE A 136
CYH A 278
None
NB1  A1590 ( 4.9A)
None
NB1  A1590 (-3.4A)
0.94A 5hieC-2j4gA:
undetectable
5hieC-2j4gA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j86 PROTEIN
SERINE-THREONINE
PHOSPHATASE


(Synechococcus
elongatus)
PF13672
(PP2C_2)
4 ILE A 175
VAL A 236
PHE A  30
ILE A 103
None
0.94A 5hieC-2j86A:
undetectable
5hieC-2j86A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kk4 UNCHARACTERIZED
PROTEIN AF_2094


(Archaeoglobus
fulgidus)
no annotation 4 VAL A  33
PHE A  37
ILE A  22
PHE A  18
None
0.97A 5hieC-2kk4A:
undetectable
5hieC-2kk4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqz SORTASE B

(Bacillus
anthracis)
PF04203
(Sortase)
4 ILE A  52
VAL A 128
ILE A  96
PHE A 172
None
0.84A 5hieC-2oqzA:
undetectable
5hieC-2oqzA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5m ARGININE REPRESSOR

(Bacillus
subtilis)
PF02863
(Arg_repressor_C)
4 ILE A 131
PHE A  84
ILE A  87
CYH A 123
None
0.94A 5hieC-2p5mA:
undetectable
5hieC-2p5mA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pg0 ACYL-COA
DEHYDROGENASE


(Geobacillus
kaustophilus)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 ILE A 362
VAL A 308
ILE A 254
PHE A 304
None
0.96A 5hieC-2pg0A:
undetectable
5hieC-2pg0A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppv UNCHARACTERIZED
PROTEIN


(Staphylococcus
epidermidis)
PF01933
(UPF0052)
4 ILE A  45
VAL A 114
ILE A  61
ASN A  99
None
0.96A 5hieC-2ppvA:
undetectable
5hieC-2ppvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0t PUTATIVE
GAMMA-CARBOXYMUCONOL
ACTONE DECARBOXYLASE
SUBUNIT


(Paraburkholderia
xenovorans)
PF02627
(CMD)
4 ILE A  83
PHE A 190
ILE A  63
PHE A 195
None
0.84A 5hieC-2q0tA:
undetectable
5hieC-2q0tA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfr PURPLE ACID
PHOSPHATASE


(Phaseolus
vulgaris)
PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N)
4 VAL A 283
PHE A 320
ASN A 335
PHE A 311
None
0.96A 5hieC-2qfrA:
undetectable
5hieC-2qfrA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgy ENOLASE FROM THE
ENVIRONMENTAL GENOME
SHOTGUN SEQUENCING
OF THE SARGASSO SEA


(-)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ILE A 284
VAL A 247
ILE A 295
CYH A 316
None
0.87A 5hieC-2qgyA:
undetectable
5hieC-2qgyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2quq CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
B


(Saccharomyces
cerevisiae)
PF16846
(Cep3)
4 VAL A 431
PHE A 415
ASN A  67
PHE A 469
None
0.87A 5hieC-2quqA:
2.7
5hieC-2quqA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8u MICROTUBULE-ASSOCIAT
ED PROTEIN RP/EB
FAMILY MEMBER 1


(Homo sapiens)
PF00307
(CH)
4 ILE A  35
VAL A  61
ASN A  25
PHE A  63
None
0.81A 5hieC-2r8uA:
undetectable
5hieC-2r8uA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vo9 L-ALANYL-D-GLUTAMATE
PEPTIDASE


(Listeria phage
A500)
PF13539
(Peptidase_M15_4)
4 ILE A  41
ILE A   9
CYH A  89
ASN A  93
None
0.97A 5hieC-2vo9A:
undetectable
5hieC-2vo9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w37 ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC


(Lactobacillus
hilgardii)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 ILE A 205
PHE A 197
ILE A 219
PHE A 165
None
0.85A 5hieC-2w37A:
undetectable
5hieC-2w37A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2


(Saccharomyces
cerevisiae)
PF03198
(Glyco_hydro_72)
PF07983
(X8)
4 ILE A 209
VAL A 230
PHE A 229
ILE A 194
None
1.00A 5hieC-2w61A:
undetectable
5hieC-2w61A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wba TRYPANOTHIONE
REDUCTASE


(Trypanosoma
brucei)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 VAL A 268
ILE A 169
ASN A 223
PHE A 270
None
None
NDP  A1496 (-4.0A)
None
0.80A 5hieC-2wbaA:
undetectable
5hieC-2wbaA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yps SORTING NEXIN-3

(Homo sapiens)
PF00787
(PX)
4 VAL A  67
PHE A 144
ILE A 126
ASN A  56
None
0.98A 5hieC-2ypsA:
undetectable
5hieC-2ypsA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9i HOMOCITRATE SYNTHASE

(Thermus
thermophilus)
PF00682
(HMGL-like)
4 ILE A 204
VAL A 269
ILE A 222
PHE A  17
None
0.93A 5hieC-3a9iA:
undetectable
5hieC-3a9iA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT
MEMBRANE-BOUND
HYDROGENASE SMALL
SUBUNIT


(Hydrogenovibrio
marinus)
PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
4 ILE B 252
VAL A 262
PHE A 261
PHE A 224
SF4  B 309 ( 4.1A)
None
None
None
0.99A 5hieC-3ayxB:
undetectable
5hieC-3ayxB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bpt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE


(Homo sapiens)
PF16113
(ECH_2)
4 ILE A 280
PHE A 175
ILE A 309
ASN A 300
None
0.93A 5hieC-3bptA:
undetectable
5hieC-3bptA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3v ARACHIN ARAH3
ISOFORM


(Arachis
hypogaea)
PF00190
(Cupin_1)
4 ILE A  21
VAL A 467
ASN A 184
PHE A 469
None
0.99A 5hieC-3c3vA:
0.8
5hieC-3c3vA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN


(Thermotoga
maritima)
no annotation 4 VAL B 126
PHE B 186
ASN B 105
PHE B 145
None
0.98A 5hieC-3c6qB:
undetectable
5hieC-3c6qB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chl ALPHA-14 GIARDIN

(Giardia
intestinalis)
PF00191
(Annexin)
4 ILE A 111
VAL A 253
ILE A 268
PHE A 249
None
0.93A 5hieC-3chlA:
undetectable
5hieC-3chlA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dcp HISTIDINOL-PHOSPHATA
SE


(Listeria
monocytogenes)
PF02811
(PHP)
PF13263
(PHP_C)
4 VAL A 243
ILE A 182
CYH A 233
PHE A 223
None
0.92A 5hieC-3dcpA:
undetectable
5hieC-3dcpA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enh UNCHARACTERIZED
PROTEIN MJ0187


(Methanocaldococcus
jannaschii)
PF08617
(CGI-121)
4 VAL C 138
ILE C 114
CYH C  87
PHE C 126
None
0.96A 5hieC-3enhC:
undetectable
5hieC-3enhC:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqn GLUCAN
1,3-BETA-GLUCOSIDASE


(Phanerochaete
chrysosporium)
PF12708
(Pectate_lyase_3)
4 VAL A 229
ILE A 283
CYH A 259
PHE A 222
None
0.92A 5hieC-3eqnA:
undetectable
5hieC-3eqnA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL


(Homo sapiens)
PF01327
(Pep_deformylase)
4 VAL A 102
ILE A 154
CYH A 164
PHE A 127
None
0.90A 5hieC-3g5kA:
undetectable
5hieC-3g5kA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h11 CASP8 AND FADD-LIKE
APOPTOSIS REGULATOR


(Homo sapiens)
PF00656
(Peptidase_C14)
4 ILE A 260
VAL A 309
PHE A 355
PHE A 271
None
0.99A 5hieC-3h11A:
undetectable
5hieC-3h11A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnp OXIDOREDUCTASE

(Bacillus cereus)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 ILE A  86
VAL A  30
ILE A  66
PHE A   7
None
0.75A 5hieC-3hnpA:
undetectable
5hieC-3hnpA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i23 OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY


(Enterococcus
faecalis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 ILE A  86
VAL A  30
ILE A  66
PHE A   7
None
0.77A 5hieC-3i23A:
undetectable
5hieC-3i23A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivu HOMOCITRATE
SYNTHASE,
MITOCHONDRIAL


(Schizosaccharomyces
pombe)
PF00682
(HMGL-like)
4 ILE A 233
VAL A 298
ILE A 251
PHE A  48
None
0.95A 5hieC-3ivuA:
undetectable
5hieC-3ivuA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jar MICROTUBULE-ASSOCIAT
ED PROTEIN RP/EB
FAMILY MEMBER 3


(Homo sapiens)
no annotation 4 ILE N  35
VAL N  61
ASN N  25
PHE N  63
None
0.83A 5hieC-3jarN:
undetectable
5hieC-3jarN:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kt4 PKHD-TYPE
HYDROXYLASE TPA1


(Saccharomyces
cerevisiae)
PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4)
4 ILE A 241
VAL A 132
ILE A 168
PHE A 128
None
0.80A 5hieC-3kt4A:
undetectable
5hieC-3kt4A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg6 PUTATIVE GLUTATHIONE
TRANSFERASE


(Coccidioides
immitis)
PF13409
(GST_N_2)
PF14497
(GST_C_3)
4 VAL A 204
PHE A 168
ILE A 174
ASN A 117
None
0.96A 5hieC-3lg6A:
undetectable
5hieC-3lg6A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nm1 THIAMINE
BIOSYNTHETIC
BIFUNCTIONAL ENZYME


([Candida]
glabrata)
PF02110
(HK)
PF02581
(TMP-TENI)
4 ILE A 257
VAL A 412
ILE A 476
PHE A 486
None
0.75A 5hieC-3nm1A:
undetectable
5hieC-3nm1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5d PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5


(Homo sapiens)
PF00254
(FKBP_C)
4 ILE A 122
VAL A  55
CYH A 107
PHE A  79
None
0.98A 5hieC-3o5dA:
undetectable
5hieC-3o5dA:
22.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 ILE A 355
ILE A 419
CYH A 424
PHE A 487
SM5  A   1 (-4.3A)
SM5  A   1 ( 4.3A)
SM5  A   1 ( 4.4A)
None
0.69A 5hieC-3omvA:
34.8
5hieC-3omvA:
77.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 ILE A 355
PHE A 408
ILE A 419
ASN A 472
SM5  A   1 (-4.3A)
None
SM5  A   1 ( 4.3A)
SM5  A   1 (-3.9A)
0.70A 5hieC-3omvA:
34.8
5hieC-3omvA:
77.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 ILE A 355
PHE A 408
ILE A 419
CYH A 424
SM5  A   1 (-4.3A)
None
SM5  A   1 ( 4.3A)
SM5  A   1 ( 4.4A)
0.46A 5hieC-3omvA:
34.8
5hieC-3omvA:
77.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 VAL A 396
PHE A 408
ILE A 419
ASN A 472
None
None
SM5  A   1 ( 4.3A)
SM5  A   1 (-3.9A)
0.98A 5hieC-3omvA:
34.8
5hieC-3omvA:
77.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opu SPAP

(Streptococcus
mutans)
PF16364
(Antigen_C)
4 ILE A1364
VAL A1445
ILE A1368
PHE A1441
None
0.97A 5hieC-3opuA:
undetectable
5hieC-3opuA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ppz SERINE/THREONINE-PRO
TEIN KINASE CTR1


(Arabidopsis
thaliana)
PF07714
(Pkinase_Tyr)
4 ILE A 557
PHE A 611
ILE A 623
PHE A 695
STU  A   1 (-4.1A)
None
None
None
1.00A 5hieC-3ppzA:
28.1
5hieC-3ppzA:
38.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr3 ENDOGLUCANASE EG-II

(Trichoderma
reesei)
PF00150
(Cellulase)
4 VAL A 290
PHE A  59
ILE A   9
ASN A 105
None
0.93A 5hieC-3qr3A:
undetectable
5hieC-3qr3A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rip GAMMA-TUBULIN
COMPLEX COMPONENT 4


(Homo sapiens)
PF04130
(Spc97_Spc98)
4 VAL A 487
ILE A 585
ASN A 651
PHE A 579
None
None
None
GOL  A 679 ( 4.3A)
0.86A 5hieC-3ripA:
undetectable
5hieC-3ripA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpw ABC TRANSPORTER

(Rhodopseudomonas
palustris)
PF13416
(SBP_bac_8)
4 PHE A 336
ILE A 196
ASN A 256
PHE A 177
None
0.97A 5hieC-3rpwA:
undetectable
5hieC-3rpwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s1s RESTRICTION
ENDONUCLEASE BPUSI


(Bacillus
pumilus)
PF02384
(N6_Mtase)
PF15516
(BpuSI_N)
4 VAL A  48
ILE A 163
ASN A 113
PHE A  61
None
0.87A 5hieC-3s1sA:
undetectable
5hieC-3s1sA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u50 TELOMERASE-ASSOCIATE
D PROTEIN 82


(Tetrahymena
thermophila)
PF08646
(Rep_fac-A_C)
4 ILE C 513
VAL C 591
ILE C 520
PHE C 653
None
0.93A 5hieC-3u50C:
undetectable
5hieC-3u50C:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE


(Sulfolobus
solfataricus)
PF00128
(Alpha-amylase)
PF09071
(Alpha-amyl_C)
4 VAL A 246
ILE A 138
ASN A 191
PHE A 249
None
None
GLC  A 604 ( 4.5A)
None
0.89A 5hieC-3vgfA:
undetectable
5hieC-3vgfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpz GLUCOKINASE

(Pseudoalteromonas
sp. AS-131)
PF02685
(Glucokinase)
4 ILE A  11
VAL A  84
ILE A  16
CYH A 324
None
0.96A 5hieC-3vpzA:
undetectable
5hieC-3vpzA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE


(Parageobacillus
thermoglucosidasius)
PF00465
(Fe-ADH)
4 ILE A 728
VAL A 824
ILE A 750
PHE A 740
None
0.74A 5hieC-3zdrA:
undetectable
5hieC-3zdrA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zkb DNA GYRASE SUBUNIT B

(Mycobacterium
tuberculosis)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
4 ILE A 308
VAL A 387
ILE A 358
PHE A 383
None
0.99A 5hieC-3zkbA:
undetectable
5hieC-3zkbA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zth STU0660

(Streptococcus
thermophilus)
PF16813
(Cas_St_Csn2)
4 ILE A 246
VAL A 202
PHE A 234
PHE A 237
None
0.95A 5hieC-3zthA:
undetectable
5hieC-3zthA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5p PROTEIN MXIA

(Shigella
flexneri)
PF00771
(FHIPEP)
4 ILE A 542
PHE A 643
ILE A 666
CYH A 580
None
MLY  A 641 ( 4.5A)
None
None
0.99A 5hieC-4a5pA:
undetectable
5hieC-4a5pA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ain GLYCINE BETAINE
TRANSPORTER BETP


(Corynebacterium
glutamicum)
PF02028
(BCCT)
4 ILE A 238
VAL A 109
ILE A 199
PHE A 106
None
0.98A 5hieC-4ainA:
undetectable
5hieC-4ainA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aoa BETA-PHENYLALANINE
AMINOTRANSFERASE


(Variovorax
paradoxus)
PF00202
(Aminotran_3)
4 VAL A 401
ILE A 412
ASN A 344
PHE A 351
None
0.93A 5hieC-4aoaA:
undetectable
5hieC-4aoaA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ars HISTIDINE ACID
PHOSPHATASE


(Hafnia alvei)
PF00328
(His_Phos_2)
4 ILE A  15
VAL A 402
ILE A 313
ASN A 298
None
1.00A 5hieC-4arsA:
undetectable
5hieC-4arsA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7p RALF

(Legionella
pneumophila)
PF01369
(Sec7)
4 ILE A  36
VAL A  58
ILE A  24
PHE A  76
None
0.91A 5hieC-4c7pA:
undetectable
5hieC-4c7pA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czx PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3


(Neurospora
crassa)
no annotation 5 ILE A  83
VAL B 626
PHE B 625
ASN A  34
PHE A  59
None
1.47A 5hieC-4czxA:
undetectable
5hieC-4czxA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fva 5'-TYROSYL-DNA
PHOSPHODIESTERASE


(Caenorhabditis
elegans)
PF03372
(Exo_endo_phos)
4 VAL A 122
ILE A 189
ASN A 261
PHE A 267
None
0.71A 5hieC-4fvaA:
undetectable
5hieC-4fvaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzy EXODEOXYRIBONUCLEASE
10


(Escherichia
coli)
PF00929
(RNase_T)
4 ILE A 142
VAL A  88
ILE A   5
PHE A  84
None
0.92A 5hieC-4fzyA:
undetectable
5hieC-4fzyA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gew 5'-TYROSYL-DNA
PHOSPHODIESTERASE


(Caenorhabditis
elegans)
PF03372
(Exo_endo_phos)
PF14555
(UBA_4)
4 VAL A 122
ILE A 189
ASN A 261
PHE A 267
None
0.72A 5hieC-4gewA:
undetectable
5hieC-4gewA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i6k AMIDOHYDROLASE
FAMILY PROTEIN


(Acinetobacter
baumannii)
PF04909
(Amidohydro_2)
4 ILE A 248
ILE A 222
ASN A 210
PHE A 217
None
0.98A 5hieC-4i6kA:
undetectable
5hieC-4i6kA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9y E3 SUMO-PROTEIN
LIGASE RANBP2


(Homo sapiens)
PF00160
(Pro_isomerase)
4 ILE A  67
VAL A 139
ILE A 156
CYH A  40
None
1.00A 5hieC-4i9yA:
undetectable
5hieC-4i9yA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j1y COMPLEMENT C1S
SUBCOMPONENT


(Homo sapiens)
PF00084
(Sushi)
PF00089
(Trypsin)
4 ILE A 548
VAL A 492
ILE A 446
PHE A 454
None
0.96A 5hieC-4j1yA:
0.4
5hieC-4j1yA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb3 HALOACID
DEHALOGENASE-LIKE
HYDROLASE


(Bacteroides
thetaiotaomicron)
PF13419
(HAD_2)
4 ILE A  26
VAL A 114
PHE A 113
PHE A  84
None
0.98A 5hieC-4jb3A:
undetectable
5hieC-4jb3A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcl CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE


(Paenibacillus
macerans)
PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
5 ILE A 318
VAL A 516
ILE A 502
ASN A 275
PHE A 580
None
None
None
EDO  A 721 ( 4.4A)
None
1.45A 5hieC-4jclA:
undetectable
5hieC-4jclA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jqt PUTATIVE GLYCOSYL
HYDROLASE


(Bacteroides
thetaiotaomicron)
PF06439
(DUF1080)
4 ILE A 156
ILE A 182
ASN A 171
PHE A 108
EDO  A 505 ( 4.4A)
None
None
None
0.98A 5hieC-4jqtA:
undetectable
5hieC-4jqtA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7g 3-HYDROXYPROLINE
DEHYDRATSE


(Agrobacterium
vitis)
PF05544
(Pro_racemase)
4 ILE B 273
VAL B 244
CYH B 291
PHE B 174
None
0.87A 5hieC-4k7gB:
0.4
5hieC-4k7gB:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN


(Archaeoglobus
fulgidus)
PF01699
(Na_Ca_ex)
4 ILE A  13
VAL A  81
ILE A 220
PHE A 227
None
0.97A 5hieC-4kppA:
undetectable
5hieC-4kppA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqn D-HYDANTOINASE

(Bacillus sp.
AR9)
PF01979
(Amidohydro_1)
4 ILE A 348
VAL A 438
ASN A 416
PHE A  83
ILE  A 348 ( 0.4A)
VAL  A 438 ( 0.6A)
ASN  A 416 ( 0.6A)
PHE  A  83 ( 1.3A)
0.96A 5hieC-4kqnA:
undetectable
5hieC-4kqnA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksf MALONYL-COA
DECARBOXYLASE


(Agrobacterium
vitis)
PF05292
(MCD)
PF17408
(MCD_N)
4 ILE A 197
VAL A 286
ILE A 266
PHE A 215
None
0.97A 5hieC-4ksfA:
undetectable
5hieC-4ksfA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m64 MELIBIOSE CARRIER
PROTEIN


(Salmonella
enterica)
PF13347
(MFS_2)
4 ILE A 250
VAL A 390
ASN A 244
PHE A 386
None
0.98A 5hieC-4m64A:
undetectable
5hieC-4m64A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mix PUTATIVE
INSECTICIDAL TOXIN


(Photorhabdus
asymbiotica)
PF04488
(Gly_transf_sug)
4 ILE A2204
VAL A2223
ILE A2226
PHE A2218
None
0.91A 5hieC-4mixA:
undetectable
5hieC-4mixA:
21.91