SIMILAR PATTERNS OF AMINO ACIDS FOR 5GLM_A_ACTA613

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cen CELLULASE CELC

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		3 ASP A  26
SER A  69
TYR A  70
 None
 0.83A 5glmA-1cenA:
undetectable		 5glmA-1cenA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ASP A 633
SER A 590
TYR A 629
 None
 0.82A 5glmA-1fcpA:
0.0		 5glmA-1fcpA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lf9 GLUCOAMYLASE

(Thermoanaerobacterium
thermosaccharolyticum) 		PF00723
(Glyco_hydro_15)
PF09137
(Glucodextran_N) 		3 ASP A 423
SER A 470
TYR A 474
 None
 0.89A 5glmA-1lf9A:
0.0		 5glmA-1lf9A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltl DNA REPLICATION
INITIATOR
(CDC21/CDC54)

(Methanothermobacter
thermautotrophicus) 		PF14551
(MCM_N)
PF17207
(MCM_OB) 		3 ASP A  55
SER A  92
TYR A  43
 None
 0.88A 5glmA-1ltlA:
0.0		 5glmA-1ltlA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o6u SEC14-LIKE PROTEIN 2

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		3 ASP A 313
SER A 370
TYR A 369
 None
 0.91A 5glmA-1o6uA:
0.0		 5glmA-1o6uA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis omega
virus) 		PF03566
(Peptidase_A21) 		3 ASP A  97
SER A 244
TYR A 453
 None
 0.87A 5glmA-1ohfA:
0.0		 5glmA-1ohfA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poy SPERMIDINE/PUTRESCIN
E-BINDING PROTEIN

(Escherichia
coli) 		PF13416
(SBP_bac_8) 		3 ASP 1 168
SER 1  83
TYR 1  85
 SPD  1 400 (-3.6A)
SPD  1 400 ( 3.7A)
None
 0.77A 5glmA-1poy1:
0.0		 5glmA-1poy1:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs1 ADP-RIBOSYLTRANSFERA
SE

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 267
SER A 391
TYR A 348
 None
 0.61A 5glmA-1qs1A:
0.0		 5glmA-1qs1A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs2 ADP-RIBOSYLTRANSFERA
SE

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 267
SER A 391
TYR A 348
 None
 0.56A 5glmA-1qs2A:
0.0		 5glmA-1qs2A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5a GLUTATHIONE
TRANSFERASE

(Anopheles
cracens) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		3 ASP A  96
SER A  72
TYR A  85
 None
 0.64A 5glmA-1r5aA:
undetectable		 5glmA-1r5aA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0h VOLTAGE-GATED
CALCIUM CHANNEL
SUBUNIT BETA2A

(Rattus
norvegicus) 		PF12052
(VGCC_beta4Aa_N) 		3 ASP A  76
SER A  86
TYR A  70
 None
 0.92A 5glmA-1t0hA:
undetectable		 5glmA-1t0hA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xez HEMOLYSIN

(Vibrio cholerae) 		PF07968
(Leukocidin)
PF12563
(Hemolysin_N)
PF16458
(Beta-prism_lec) 		3 ASP A 605
SER A 636
TYR A 609
 None
 0.91A 5glmA-1xezA:
0.7		 5glmA-1xezA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yr7 ATP(GTP)BINDING
PROTEIN

(Pyrococcus
abyssi) 		PF03029
(ATP_bind_1) 		3 ASP A  36
SER A  73
TYR A  74
 GSP  A 401 (-4.6A)
None
None
 0.79A 5glmA-1yr7A:
undetectable		 5glmA-1yr7A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axp HYPOTHETICAL PROTEIN
BSU20280

(Bacillus
subtilis) 		PF02223
(Thymidylate_kin) 		3 ASP A  10
SER A  66
TYR A  70
 None
 0.86A 5glmA-2axpA:
undetectable		 5glmA-2axpA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE

(Prosthecochloris
vibrioformis) 		PF00490
(ALAD) 		3 ASP A  82
SER A 170
TYR A 197
 None
DSB  A1330 (-3.4A)
None
 0.89A 5glmA-2c1hA:
undetectable		 5glmA-2c1hA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2l PEPTIDOGLYCAN
RECOGNITION
PROTEIN-LC ISOFORM
LCX

(Drosophila
melanogaster) 		PF01510
(Amidase_2) 		3 ASP X 406
SER X 378
TYR X 410
 None
 0.92A 5glmA-2f2lX:
undetectable		 5glmA-2f2lX:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgq OUTER MEMBRANE PORIN
PROTEIN 32

(Delftia
acidovorans) 		PF13609
(Porin_4) 		3 ASP X 179
SER X 103
TYR X 104
 None
 0.88A 5glmA-2fgqX:
undetectable		 5glmA-2fgqX:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fwr DNA REPAIR PROTEIN
RAD25

(Archaeoglobus
fulgidus) 		PF04851
(ResIII)
PF16203
(ERCC3_RAD25_C) 		3 ASP A 180
SER A 208
TYR A 209
 None
 0.89A 5glmA-2fwrA:
undetectable		 5glmA-2fwrA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3z C2 TOXIN COMPONENT I

(Clostridium
botulinum) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 220
SER A 353
TYR A 298
 None
 0.86A 5glmA-2j3zA:
undetectable		 5glmA-2j3zA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbw 2,6-DIHYDROXY-PSEUDO
-OXYNICOTINE
HYDROLASE

(Paenarthrobacter
nicotinovorans) 		PF06500
(DUF1100) 		3 ASP A  28
SER A  74
TYR A  52
 None
 0.79A 5glmA-2jbwA:
undetectable		 5glmA-2jbwA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jem ENDO-BETA-1,4-GLUCAN
ASE

(Bacillus
licheniformis) 		PF01670
(Glyco_hydro_12) 		3 ASP A 257
SER A  94
TYR A  46
 None
 0.70A 5glmA-2jemA:
undetectable		 5glmA-2jemA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE

(Homo sapiens) 		PF05770
(Ins134_P3_kin) 		3 ASP X 295
SER X 109
TYR X 110
 None
 0.79A 5glmA-2odtX:
undetectable		 5glmA-2odtX:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbg 6-PHOSPHO-BETA-D-GAL
ACTOSIDASE

(Lactococcus
lactis) 		PF00232
(Glyco_hydro_1) 		3 ASP A 356
SER A 301
TYR A 222
 None
 0.91A 5glmA-2pbgA:
undetectable		 5glmA-2pbgA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbj PROSTAGLANDIN E
SYNTHASE 2

(Macaca
fascicularis) 		PF13417
(GST_N_3) 		3 ASP A 240
SER A 166
TYR A 209
 None
GSH  A 477 ( 4.6A)
None
 0.88A 5glmA-2pbjA:
undetectable		 5glmA-2pbjA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcc RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA

(Bacillus
halodurans) 		PF00268
(Ribonuc_red_sm) 		3 ASP A 258
SER A 285
TYR A 301
 None
 0.89A 5glmA-2rccA:
undetectable		 5glmA-2rccA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhq PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Staphylococcus
haemolyticus) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 ASP B 378
SER B 402
TYR B 223
 None
 0.86A 5glmA-2rhqB:
undetectable		 5glmA-2rhqB:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tmk THYMIDYLATE KINASE

(Saccharomyces
cerevisiae) 		PF02223
(Thymidylate_kin) 		3 ASP A  14
SER A  98
TYR A 102
 ATM  A 217 ( 3.0A)
ATM  A 217 ( 4.8A)
ATM  A 217 (-3.4A)
 0.74A 5glmA-2tmkA:
undetectable		 5glmA-2tmkA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpq ACETYL-COA
CARBOXYLASE

(Staphylococcus
aureus) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  35
SER A  58
TYR A  59
 None
 0.88A 5glmA-2vpqA:
undetectable		 5glmA-2vpqA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vqd BIOTIN CARBOXYLASE

(Pseudomonas
aeruginosa) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  36
SER A  59
TYR A  60
 None
 0.88A 5glmA-2vqdA:
undetectable		 5glmA-2vqdA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0s THYMIDYLATE KINASE

(Vaccinia virus) 		PF02223
(Thymidylate_kin) 		3 ASP A  13
SER A  97
TYR A 101
 MG  A1206 ( 3.4A)
BVP  A1207 ( 4.2A)
BVP  A1207 (-3.7A)
 0.84A 5glmA-2w0sA:
undetectable		 5glmA-2w0sA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wn4 ADP-RIBOSYLTRANSFERA
SE ENZYMATIC
COMPONENT

(Clostridioides
difficile) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 219
SER A 350
TYR A 301
 None
 0.66A 5glmA-2wn4A:
undetectable		 5glmA-2wn4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y38 LAMININ SUBUNIT
ALPHA-5

(Mus musculus) 		PF00053
(Laminin_EGF)
PF00055
(Laminin_N) 		3 ASP A 356
SER A 250
TYR A 251
 None
None
NAG  A3001 (-3.8A)
 0.88A 5glmA-2y38A:
undetectable		 5glmA-2y38A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yof THYMIDYLATE KINASE

(Plasmodium
falciparum) 		PF02223
(Thymidylate_kin) 		3 ASP A  17
SER A 103
TYR A 107
 74W  A 211 (-2.6A)
74W  A 211 ( 4.4A)
74W  A 211 (-3.5A)
 0.83A 5glmA-2yofA:
undetectable		 5glmA-2yofA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhl GALECTIN-9

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		3 ASP A 100
SER A 146
TYR A 144
 None
 0.76A 5glmA-2zhlA:
undetectable		 5glmA-2zhlA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av6 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 ASP A1522
SER A1037
TYR A1038
 None
 0.76A 5glmA-3av6A:
0.2		 5glmA-3av6A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc1 RAS-RELATED PROTEIN
RAB-27A

(Mus musculus) 		PF00071
(Ras) 		3 ASP A 127
SER A 123
TYR A 122
 None
 0.70A 5glmA-3bc1A:
undetectable		 5glmA-3bc1A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bu7 GENTISATE
1,2-DIOXYGENASE

(Ruegeria
pomeroyi) 		PF07883
(Cupin_2) 		3 ASP A 255
SER A 345
TYR A 298
 FE2  A 500 ( 3.8A)
None
None
 0.71A 5glmA-3bu7A:
undetectable		 5glmA-3bu7A:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buz IOTA TOXIN COMPONENT
IA

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 212
SER A 343
TYR A 294
 None
 0.67A 5glmA-3buzA:
undetectable		 5glmA-3buzA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dte IRRE PROTEIN

(Deinococcus
deserti) 		PF06114
(Peptidase_M78) 		3 ASP A 216
SER A 233
TYR A 234
 None
 0.84A 5glmA-3dteA:
undetectable		 5glmA-3dteA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnt HAP PROTEIN

(Plasmodium
falciparum) 		PF00026
(Asp) 		3 ASP A  68
SER A  58
TYR A  64
 None
 0.80A 5glmA-3fntA:
undetectable		 5glmA-3fntA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g8d BIOTIN CARBOXYLASE

(Escherichia
coli) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  36
SER A  59
TYR A  60
 None
 0.86A 5glmA-3g8dA:
undetectable		 5glmA-3g8dA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5l PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER

(Ruegeria
pomeroyi) 		PF13458
(Peripla_BP_6) 		3 ASP A 417
SER A 409
TYR A 301
 None
 0.84A 5glmA-3h5lA:
undetectable		 5glmA-3h5lA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lv4 GLYCOSIDE HYDROLASE
YXIA

(Bacillus
licheniformis) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		3 ASP A 107
SER A 320
TYR A 231
 None
 0.90A 5glmA-3lv4A:
0.0		 5glmA-3lv4A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ouu BIOTIN CARBOXYLASE

(Campylobacter
jejuni) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  37
SER A  60
TYR A  61
 None
 0.90A 5glmA-3ouuA:
undetectable		 5glmA-3ouuA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p54 ENVELOPE
GLYCOPROTEIN

(Japanese
encephalitis
virus) 		PF00869
(Flavi_glycoprot)
PF02832
(Flavi_glycop_C) 		3 ASP A 332
SER A 329
TYR A 328
 None
 0.82A 5glmA-3p54A:
undetectable		 5glmA-3p54A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN

(Bacillus
subtilis) 		PF04069
(OpuAC) 		3 ASP A 233
SER A 155
TYR A 187
 None
 0.90A 5glmA-3ppoA:
undetectable		 5glmA-3ppoA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxg NEGATIVE REGULATOR
OF GENETIC
COMPETENCE CLPC/MECB
ADAPTER PROTEIN MECA
1

(Bacillus
subtilis;
Bacillus
subtilis) 		PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N)
PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N) 		3 ASP A 428
SER a 156
TYR a 161
 None
 0.58A 5glmA-3pxgA:
undetectable		 5glmA-3pxgA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxi NEGATIVE REGULATOR
OF GENETIC
COMPETENCE CLPC/MECB
ADAPTER PROTEIN MECA
1

(Bacillus
subtilis;
Bacillus
subtilis) 		PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small)
PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		3 ASP A 428
SER a 156
TYR a 161
 None
 0.50A 5glmA-3pxiA:
undetectable		 5glmA-3pxiA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qv2 5-CYTOSINE DNA
METHYLTRANSFERASE

(Entamoeba
histolytica) 		PF00145
(DNA_methylase) 		3 ASP A 293
SER A 202
TYR A 203
 None
 0.86A 5glmA-3qv2A:
undetectable		 5glmA-3qv2A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvi HISTO-ASPARTIC
PROTEASE

(Plasmodium
falciparum) 		PF00026
(Asp) 		3 ASP A  68
SER A  58
TYR A  64
 ASP  A  68 ( 0.5A)
SER  A  58 ( 0.0A)
TYR  A  64 ( 1.3A)
 0.66A 5glmA-3qviA:
undetectable		 5glmA-3qviA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ren GLYCOSYL HYDROLASE,
FAMILY 8

(Clostridium
perfringens) 		PF01270
(Glyco_hydro_8) 		3 ASP A 103
SER A 153
TYR A 156
 None
 0.81A 5glmA-3renA:
undetectable		 5glmA-3renA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rwl CYTOCHROME P450
ALKANE HYDROXYLASE 1
CYP153A7

(Sphingopyxis
macrogoltabida) 		PF00067
(p450) 		3 ASP A  18
SER A  56
TYR A  54
 None
 0.62A 5glmA-3rwlA:
undetectable		 5glmA-3rwlA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9s METHYLCROTONYL-COA
CARBOXYLASE,
ALPHA-SUBUNIT

(Pseudomonas
aeruginosa) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  83
SER A 106
TYR A 107
 None
 0.85A 5glmA-3u9sA:
undetectable		 5glmA-3u9sA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0r PUTATIVE AMINO ACID
BINDING PROTEIN

(Streptococcus
mutans) 		PF00497
(SBP_bac_3) 		3 ASP A 235
SER A  88
TYR A 191
 None
 0.90A 5glmA-4c0rA:
undetectable		 5glmA-4c0rA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4con ANAEROBIC
RIBONUCLEOSIDE-TRIPH
OSPHATE REDUCTASE

(Thermotoga
maritima) 		PF13597
(NRDD) 		3 ASP A 363
SER A 288
TYR A 318
 None
 0.87A 5glmA-4conA:
undetectable		 5glmA-4conA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gx7 CYTOLYSIN AND
HEMOLYSIN HLYA
PORE-FORMING TOXIN

(Vibrio cholerae) 		PF16458
(Beta-prism_lec) 		3 ASP A 605
SER A 636
TYR A 609
 None
 0.91A 5glmA-4gx7A:
undetectable		 5glmA-4gx7A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kav YHBX/YHJW/YIJP/YJDB
FAMILY PROTEIN

(Neisseria
meningitidis) 		PF00884
(Sulfatase) 		3 ASP A 420
SER A 253
TYR A 252
 None
 0.90A 5glmA-4kavA:
undetectable		 5glmA-4kavA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kuj PROTEIN KINASE,
PUTATIVE

(Entamoeba
histolytica) 		PF02816
(Alpha_kinase) 		3 ASP A 138
SER A 134
TYR A  25
 None
 0.81A 5glmA-4kujA:
undetectable		 5glmA-4kujA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mm0 P450-LIKE
MONOOXYGENASE

(Streptomyces
griseoviridis) 		PF00067
(p450) 		3 ASP A 165
SER A 239
TYR A 235
 None
 0.63A 5glmA-4mm0A:
undetectable		 5glmA-4mm0A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mru SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		3 ASP A 406
SER A 333
TYR A 334
 None
 0.73A 5glmA-4mruA:
undetectable		 5glmA-4mruA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mv3 BIOTIN CARBOXYLASE

(Haemophilus
influenzae) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  36
SER A  59
TYR A  60
 None
 0.89A 5glmA-4mv3A:
undetectable		 5glmA-4mv3A:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nso IMMUNITY PROTEIN

(Vibrio cholerae) 		no annotation 3 ASP B 120
SER B  61
TYR B  64
 None
 0.92A 5glmA-4nsoB:
undetectable		 5glmA-4nsoB:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		3 ASP A 961
SER A1009
TYR A1010
 None
 0.90A 5glmA-4o9xA:
undetectable		 5glmA-4o9xA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rn3 HAD SUPERFAMILY
HYDROLASE

(Geobacter
sulfurreducens) 		PF13419
(HAD_2) 		3 ASP A 104
SER A 133
TYR A 134
 None
 0.86A 5glmA-4rn3A:
undetectable		 5glmA-4rn3A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru0 PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC
TRANSPORTER,
PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN

(Pseudomonas
protegens) 		PF13458
(Peripla_BP_6) 		3 ASP A 272
SER A  46
TYR A 323
 None
 0.64A 5glmA-4ru0A:
undetectable		 5glmA-4ru0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6x NANOBODY NBFEDF7

(Lama glama) 		PF07686
(V-set) 		3 ASP B 114
SER B 100
TYR B  29
 None
 0.88A 5glmA-4w6xB:
undetectable		 5glmA-4w6xB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd9 NISIN BIOSYNTHESIS
PROTEIN NISB

(Lactococcus
lactis) 		PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C) 		3 ASP A 445
SER A 106
TYR A 108
 None
 0.91A 5glmA-4wd9A:
undetectable		 5glmA-4wd9A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr7 PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3

(Saccharomyces
cerevisiae) 		no annotation 3 ASP L 359
SER L 315
TYR L 291
 None
 0.91A 5glmA-4xr7L:
undetectable		 5glmA-4xr7L:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwl EXOGLUCANASE S

(Clostridium
cellulovorans) 		PF02011
(Glyco_hydro_48) 		3 ASP A  77
SER A 247
TYR A 248
 None
 0.88A 5glmA-4xwlA:
undetectable		 5glmA-4xwlA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3

(Branchiostoma
belcheri) 		PF01510
(Amidase_2) 		3 ASP A 135
SER A 107
TYR A 139
 None
 0.92A 5glmA-4z8iA:
undetectable		 5glmA-4z8iA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE

(Vesicular
stomatitis
virus) 		PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap) 		3 ASP A 125
SER A 871
TYR A 875
 None
 0.81A 5glmA-5a22A:
undetectable		 5glmA-5a22A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7m BETA-XYLOSIDASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ASP A 381
SER A 552
TYR A 435
 NAG  A1501 ( 4.9A)
NAG  A1501 (-2.7A)
NAG  A1502 (-4.0A)
 0.82A 5glmA-5a7mA:
undetectable		 5glmA-5a7mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czl GLUCANASE

(Raoultella
ornithinolytica) 		PF01270
(Glyco_hydro_8) 		3 ASP A  57
SER A 115
TYR A 116
 None
 0.73A 5glmA-5czlA:
undetectable		 5glmA-5czlA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4e INTERLEUKIN-4
RECEPTOR SUBUNIT
ALPHA

(Homo sapiens) 		PF09238
(IL4Ra_N) 		3 ASP B 146
SER B 171
TYR B 172
 None
 0.92A 5glmA-5e4eB:
undetectable		 5glmA-5e4eB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN

(Pseudomonas
fluorescens) 		PF00990
(GGDEF) 		3 ASP A 354
SER A 424
TYR A 418
 None
 0.85A 5glmA-5euhA:
undetectable		 5glmA-5euhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exr DNA PRIMASE LARGE
SUBUNIT

(Homo sapiens) 		PF04104
(DNA_primase_lrg) 		3 ASP B 436
SER B  62
TYR B  63
 None
 0.59A 5glmA-5exrB:
undetectable		 5glmA-5exrB:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5gll GLYCOSIDE HYDROLASE
FAMILY 43

(uncultured
bacterium) 		PF04616
(Glyco_hydro_43) 		3 ASP A  64
SER A 131
TYR A 136
 ACT  A 406 (-4.6A)
ACT  A 406 (-3.0A)
ACT  A 406 (-4.8A)
 0.10A 5glmA-5gllA:
62.5		 5glmA-5gllA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1z PUTATIVE CYP ALKANE
HYDROXYLASE
CYP153D17

(Sphingomonas
sp. PAMC 26605) 		PF00067
(p450) 		3 ASP A  12
SER A  50
TYR A  48
 None
 0.77A 5glmA-5h1zA:
undetectable		 5glmA-5h1zA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hfn CEPHALOSPORIN-C
DEACETYLASE

(Thermotoga
maritima) 		PF05448
(AXE1) 		3 ASP A  23
SER A 251
TYR A 252
 None
 0.92A 5glmA-5hfnA:
undetectable		 5glmA-5hfnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hss LINALOOL
DEHYDRATASE/ISOMERAS
E

(Castellaniella
defragrans) 		no annotation 3 ASP A 343
SER A  66
TYR A  70
 None
 0.72A 5glmA-5hssA:
undetectable		 5glmA-5hssA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5j NITROUS-OXIDE
REDUCTASE

(Shewanella
denitrificans) 		no annotation 3 ASP A 348
SER A 275
TYR A 246
 None
 0.87A 5glmA-5i5jA:
5.9		 5glmA-5i5jA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jy1 PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE

(Paraburkholderia
xenovorans) 		PF13561
(adh_short_C2) 		3 ASP A 145
SER A 256
TYR A 254
 None
 0.84A 5glmA-5jy1A:
undetectable		 5glmA-5jy1A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jyl CADHERIN-3
SCFV TSP7

(Homo sapiens;
Mus musculus) 		PF00028
(Cadherin)
PF07686
(V-set) 		3 ASP A  90
SER A  87
TYR B  54
 GOL  B 301 ( 4.7A)
None
GOL  B 301 (-3.9A)
 0.86A 5glmA-5jylA:
undetectable		 5glmA-5jylA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lgk IG EPSILON CHAIN C
REGION
LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR

(Homo sapiens;
Homo sapiens) 		PF07654
(C1-set)
PF00059
(Lectin_C) 		3 ASP A 409
SER A 378
TYR E 189
 None
 0.87A 5glmA-5lgkA:
undetectable		 5glmA-5lgkA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5li4 TAIL SHEATH PROTEIN

(Staphylococcus
phage 812) 		no annotation 3 ASP A 402
SER A  78
TYR A  82
 None
 0.91A 5glmA-5li4A:
undetectable		 5glmA-5li4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm7 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA

(Escherichia
coli) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		3 ASP A 166
SER A 185
TYR A 184
 None
 0.91A 5glmA-5lm7A:
undetectable		 5glmA-5lm7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lta PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind) 		3 ASP A 622
SER A 549
TYR A 591
 None
 0.91A 5glmA-5ltaA:
undetectable		 5glmA-5ltaA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlk ACETYL-COA
CARBOXYLASE

(Mycobacterium
tuberculosis) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASP A  46
SER A  69
TYR A  70
 None
 0.83A 5glmA-5mlkA:
undetectable		 5glmA-5mlkA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv6 TRANSFORMING GROWTH
FACTOR-BETA-INDUCED
PROTEIN IG-H3

(Homo sapiens) 		PF02469
(Fasciclin) 		3 ASP A 299
SER A 407
TYR A 488
 None
 0.86A 5glmA-5nv6A:
undetectable		 5glmA-5nv6A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5twa BCL-X HOMOLOGOUS
PROTEIN, BHP2

(Geodia cydonium) 		PF00452
(Bcl-2) 		3 ASP A 172
SER A  18
TYR A  22
 None
 0.83A 5glmA-5twaA:
undetectable		 5glmA-5twaA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uve SUBSTRATE-BINDING
REGION OF ABC-TYPE
GLYCINE BETAINE
TRANSPORT SYSTEM

(Brucella
abortus) 		PF04069
(OpuAC) 		3 ASP A 234
SER A 147
TYR A 181
 None
 0.84A 5glmA-5uveA:
undetectable		 5glmA-5uveA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1u CARBOXYLIC ESTER
HYDROLASE

(Culex
quinquefasciatus) 		PF00135
(COesterase) 		3 ASP A 124
SER A  20
TYR A  28
 None
 0.82A 5glmA-5w1uA:
undetectable		 5glmA-5w1uA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w70 L-GLUTAMINE:2-DEOXY-
SCYLLO-INOSOSE
AMINOTRANSFERASE

(Streptomyces
ribosidificus) 		PF01041
(DegT_DnrJ_EryC1) 		3 ASP A 288
SER A 151
TYR A 310
 None
 0.75A 5glmA-5w70A:
undetectable		 5glmA-5w70A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywp JEV E PROTEIN

(Japanese
encephalitis
virus) 		no annotation 3 ASP A 332
SER A 329
TYR A 328
 None
 0.91A 5glmA-5ywpA:
undetectable		 5glmA-5ywpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ba5 VARIABLE DOMAIN
HEAVY CHAIN,
ANTIBODY R11
INACTIVE
TYROSINE-PROTEIN
KINASE TRANSMEMBRANE
RECEPTOR ROR1

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ASP M 378
SER B  97
TYR B  96
 None
 0.71A 5glmA-6ba5M:
undetectable		 5glmA-6ba5M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bxa TOLL-LIKE RECEPTOR
5B, VARIABLE
LYMPHOCYTE RECEPTOR
B CHIMERA
VARIABLE LYMPHOCYTE
RECEPTOR 2

(Eptatretus
burgeri;
Danio rerio;
Petromyzon
marinus) 		no annotation
no annotation 		3 ASP A  53
SER C  57
TYR C  81
 None
 0.80A 5glmA-6bxaA:
undetectable		 5glmA-6bxaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A 362
SER A 158
TYR A 474
 None
 0.77A 5glmA-6c26A:
undetectable		 5glmA-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2

(Saccharomyces
cerevisiae) 		no annotation 3 ASP B 804
SER B 851
TYR B 798
 None
 0.74A 5glmA-6f42B:
undetectable		 5glmA-6f42B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
A, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 3 ASP a 179
SER a 145
TYR a 148
 None
 0.78A 5glmA-6fkha:
undetectable		 5glmA-6fkha:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnu METHYLENETETRAHYDROF
OLATE REDUCTASE 1

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A  90
SER A 140
TYR A 136
 None
 0.88A 5glmA-6fnuA:
undetectable		 5glmA-6fnuA:
undetectable