SIMILAR PATTERNS OF AMINO ACIDS FOR 5G48_A_1FLA1375_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8u PROTEIN (MALATE
DEHYDROGENASE)


(Aquaspirillum
arcticum)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 THR A 156
LEU A 130
ILE A 253
LEU A  88
None
0.74A 5g48A-1b8uA:
undetectable
5g48A-1b8uA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8x PROTEIN (AML-1B)

(Escherichia
coli)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 LEU A  20
PRO A   2
ILE A  74
LEU A  19
None
0.94A 5g48A-1b8xA:
undetectable
5g48A-1b8xA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE


(Rattus
norvegicus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 LEU A  21
PRO A   3
ILE A  75
LEU A  20
None
0.73A 5g48A-1bg5A:
undetectable
5g48A-1bg5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyg CYCLODEXTRIN
GLUCANOTRANSFERASE


(Geobacillus
stearothermophilus)
PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C)
4 LEU A 342
ILE A 354
PRO A 352
LEU A 345
None
0.97A 5g48A-1cygA:
undetectable
5g48A-1cygA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iv8 MALTOOLIGOSYL
TREHALOSE SYNTHASE


(Sulfolobus
acidocaldarius)
PF00128
(Alpha-amylase)
PF09196
(DUF1953)
4 LEU A 639
PRO A 714
ILE A 716
LEU A 642
MLZ  A 638 ( 4.2A)
None
None
MLZ  A 638 ( 4.6A)
0.90A 5g48A-1iv8A:
undetectable
5g48A-1iv8A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lm7 SUBDOMAIN OF
DESMOPLAKIN
CARBOXY-TERMINAL
DOMAIN (DPCT)


(Homo sapiens)
PF00681
(Plectin)
4 PRO A2418
ILE A2263
PRO A2304
LEU A2443
None
0.94A 5g48A-1lm7A:
undetectable
5g48A-1lm7A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq2 BETA-D-GLUCAN
GLUCOHYDROLASE
ISOENZYME EXO1


(Hordeum vulgare)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
4 THR A 554
LEU A 557
ILE A 481
LEU A 406
None
0.93A 5g48A-1lq2A:
undetectable
5g48A-1lq2A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrt INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Tritrichomonas
suis)
PF00478
(IMPDH)
4 THR A 465
LEU A 469
PRO A  53
LEU A 371
None
0.95A 5g48A-1lrtA:
undetectable
5g48A-1lrtA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4u TYPE II QUINOLIC
ACID
PHOSPHORIBOSYLTRANSF
ERASE


(Thermotoga
maritima)
PF01729
(QRPTase_C)
PF02749
(QRPTase_N)
4 THR A  30
LEU A  87
ILE A 271
LEU A  88
None
0.71A 5g48A-1o4uA:
undetectable
5g48A-1o4uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pn3 GLYCOSYLTRANSFERASE
GTFA


(Amycolatopsis
orientalis)
PF03033
(Glyco_transf_28)
5 THR A 354
LEU A 352
PRO A 308
ILE A 310
LEU A 348
None
1.18A 5g48A-1pn3A:
undetectable
5g48A-1pn3A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxo CHORISMATE SYNTHASE

(Streptococcus
pneumoniae)
PF01264
(Chorismate_synt)
4 PRO A 226
ILE A 362
PRO A  22
LEU A 149
None
None
EDO  A3006 (-3.9A)
None
0.80A 5g48A-1qxoA:
undetectable
5g48A-1qxoA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1snx TYROSINE-PROTEIN
KINASE ITK/TSK


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 LEU A 612
ILE A 590
PRO A 603
LEU A 608
None
0.88A 5g48A-1snxA:
undetectable
5g48A-1snxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6


(Saccharomyces
cerevisiae)
PF00443
(UCH)
4 THR A 311
LEU A 261
PRO A 307
LEU A 276
None
0.90A 5g48A-1vjvA:
undetectable
5g48A-1vjvA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2avt DNA POLYMERASE III
BETA SUBUNIT


(Streptococcus
pyogenes)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 THR A 180
PRO A 250
PRO A 356
LEU A 371
None
0.61A 5g48A-2avtA:
35.9
5g48A-2avtA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN


(Streptococcus
pneumoniae)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 LEU A 185
PRO A 250
PRO A 356
LEU A 371
None
0.68A 5g48A-2awaA:
36.1
5g48A-2awaA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN


(Streptococcus
pneumoniae)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 THR A 180
LEU A 185
PRO A 250
LEU A 371
None
0.75A 5g48A-2awaA:
36.1
5g48A-2awaA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eg9 ADP-RIBOSYL CYCLASE
1


(Mus musculus)
PF02267
(Rib_hydrolayse)
4 THR A 118
LEU A 153
ILE A  89
LEU A 154
None
0.83A 5g48A-2eg9A:
undetectable
5g48A-2eg9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fwu SODIUM/CALCIUM
EXCHANGER 1


(Canis lupus)
PF03160
(Calx-beta)
4 THR A 541
LEU A 589
ILE A 571
LEU A 642
None
0.95A 5g48A-2fwuA:
undetectable
5g48A-2fwuA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g28 PYRUVATE
DEHYDROGENASE E1
COMPONENT


(Escherichia
coli)
PF00456
(Transketolase_N)
4 THR A 246
LEU A 250
ILE A 202
LEU A 253
None
0.89A 5g48A-2g28A:
undetectable
5g48A-2g28A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2in3 HYPOTHETICAL PROTEIN

(Nitrosomonas
europaea)
PF01323
(DSBA)
4 THR A 205
LEU A 203
ILE A 189
LEU A 199
None
0.86A 5g48A-2in3A:
undetectable
5g48A-2in3A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2klt SODIUM/CALCIUM
EXCHANGER 1


(Canis lupus)
PF03160
(Calx-beta)
4 THR A 541
LEU A 589
ILE A 571
LEU A 641
None
0.92A 5g48A-2kltA:
undetectable
5g48A-2kltA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N)
4 THR A 943
LEU A1074
ILE A1053
LEU A 879
None
0.73A 5g48A-2nz9A:
undetectable
5g48A-2nz9A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qez ETHANOLAMINE
AMMONIA-LYASE HEAVY
CHAIN


(Listeria
monocytogenes)
PF06751
(EutB)
4 THR A 220
THR A 222
PRO A 163
LEU A 161
None
0.96A 5g48A-2qezA:
undetectable
5g48A-2qezA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzw CANDIDAPEPSIN-1

(Candida
albicans)
PF00026
(Asp)
4 THR A 224
LEU A 298
ILE A 234
LEU A 296
None
0.80A 5g48A-2qzwA:
undetectable
5g48A-2qzwA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbm PROTEIN-TYROSINE-PHO
SPHATASE


(Shewanella sp.)
PF00149
(Metallophos)
4 THR A 170
LEU A 172
ILE A  26
LEU A  31
None
0.88A 5g48A-2zbmA:
undetectable
5g48A-2zbmA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zv7 TYROSINE-PROTEIN
KINASE LYN


(Mus musculus)
PF07714
(Pkinase_Tyr)
4 LEU A 497
ILE A 475
PRO A 488
LEU A 493
None
0.90A 5g48A-2zv7A:
undetectable
5g48A-2zv7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dgz THIOREDOXIN
REDUCTASE 2


(Mus musculus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 THR A 240
PRO A 369
PRO A 185
LEU A 209
None
0.71A 5g48A-3dgzA:
undetectable
5g48A-3dgzA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4e CYTOCHROME P450 2E1

(Homo sapiens)
PF00067
(p450)
4 THR A 306
PRO A 176
ILE A 172
LEU A 312
None
0.95A 5g48A-3e4eA:
undetectable
5g48A-3e4eA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f1v DNA POLYMERASE III
SUBUNIT BETA


(Escherichia
coli)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 THR A 172
LEU A 177
PRO A 242
MET A 362
None
0.62A 5g48A-3f1vA:
37.6
5g48A-3f1vA:
26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmx TARTRATE
DEHYDROGENASE/DECARB
OXYLASE


(Pseudomonas
putida)
PF00180
(Iso_dh)
4 THR X 350
ILE X  16
PRO X 283
MET X 302
None
None
NH4  X 402 (-3.5A)
None
0.86A 5g48A-3fmxX:
undetectable
5g48A-3fmxX:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g10 CCR4-NOT COMPLEX
SUBUNIT CAF1


(Schizosaccharomyces
pombe)
PF04857
(CAF1)
4 THR A 104
LEU A  91
ILE A  37
LEU A  40
None
0.95A 5g48A-3g10A:
undetectable
5g48A-3g10A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gx8 MONOTHIOL
GLUTAREDOXIN-5,
MITOCHONDRIAL


(Saccharomyces
cerevisiae)
PF00462
(Glutaredoxin)
4 THR A  54
ILE A  67
PRO A 105
LEU A  49
None
0.83A 5g48A-3gx8A:
undetectable
5g48A-3gx8A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE


(Sulfurisphaera
tokodaii)
PF00128
(Alpha-amylase)
PF09196
(DUF1953)
4 LEU A 627
PRO A 699
ILE A 701
LEU A 630
None
0.93A 5g48A-3hjeA:
undetectable
5g48A-3hjeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE
FAD-SUBUNIT


(Eubacterium
barkeri)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
4 THR C 110
LEU C  74
ILE C  53
LEU C  59
FAD  C 900 (-3.0A)
None
None
None
0.72A 5g48A-3hrdC:
undetectable
5g48A-3hrdC:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isl PURINE CATABOLISM
PROTEIN PUCG


(Bacillus
subtilis)
PF00266
(Aminotran_5)
4 ILE A 134
PRO A  94
LEU A  92
MET A 144
None
0.91A 5g48A-3islA:
undetectable
5g48A-3islA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbl NLR FAMILY CARD
DOMAIN-CONTAINING
PROTEIN 4


(Mus musculus)
no annotation 4 THR K 278
ILE K 287
PRO K 164
LEU K 166
None
0.81A 5g48A-3jblK:
undetectable
5g48A-3jblK:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN


(Francisella
tularensis)
PF12710
(HAD)
4 THR A 128
PRO A  63
ILE A  68
PRO A 111
None
0.74A 5g48A-3kd3A:
undetectable
5g48A-3kd3A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfo NUCLEOPORIN NUP133

(Saccharomyces
cerevisiae)
no annotation 4 LEU A1058
PRO A1079
ILE A1045
LEU A1057
None
0.88A 5g48A-3kfoA:
undetectable
5g48A-3kfoA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA


(Homo sapiens)
PF16454
(PI3K_P85_iSH2)
4 THR A 540
LEU A 542
ILE A 481
LEU A 546
None
0.92A 5g48A-3mttA:
undetectable
5g48A-3mttA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mve UPF0255 PROTEIN
VV1_0328


(Vibrio
vulnificus)
PF06500
(DUF1100)
4 THR A  32
LEU A  36
ILE A 331
LEU A  37
None
0.94A 5g48A-3mveA:
undetectable
5g48A-3mveA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntx CYTOPLASMIC
L-ASPARAGINASE I


(Yersinia pestis)
PF00710
(Asparaginase)
4 THR A 307
LEU A 309
ILE A 212
LEU A 313
None
0.96A 5g48A-3ntxA:
undetectable
5g48A-3ntxA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmd CONSERVED DOMAIN
PROTEIN


(Bacillus
anthracis)
PF09385
(HisK_N)
4 LEU A  96
ILE A 113
PRO A 104
LEU A  99
None
0.67A 5g48A-3pmdA:
undetectable
5g48A-3pmdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3puk SYNTAXIN-BINDING
PROTEIN 3


(Mus musculus)
PF00995
(Sec1)
4 LEU A  45
ILE A  18
PRO A 142
LEU A  44
None
0.95A 5g48A-3pukA:
undetectable
5g48A-3pukA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rb9 DNA POLYMERASE III
SUBUNIT BETA


(Mycobacterium
tuberculosis)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 THR A 181
LEU A 186
PRO A 259
LEU A 394
MET A 396
None
0.66A 5g48A-3rb9A:
35.9
5g48A-3rb9A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rb9 DNA POLYMERASE III
SUBUNIT BETA


(Mycobacterium
tuberculosis)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 THR A 181
LEU A 186
PRO A 362
LEU A 394
MET A 396
None
0.44A 5g48A-3rb9A:
35.9
5g48A-3rb9A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rqz METALLOPHOSPHOESTERA
SE


(Sphaerobacter
thermophilus)
PF12850
(Metallophos_2)
4 PRO A 117
ILE A 125
PRO A 165
LEU A 152
None
0.76A 5g48A-3rqzA:
undetectable
5g48A-3rqzA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sip CASPASE

(Drosophila
melanogaster)
PF00656
(Peptidase_C14)
4 THR B 247
LEU B 173
ILE B 211
LEU A 132
None
0.88A 5g48A-3sipB:
undetectable
5g48A-3sipB:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tch PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN


(Escherichia
coli)
PF00496
(SBP_bac_5)
4 THR A 190
LEU A 185
PRO A  82
LEU A  74
None
0.95A 5g48A-3tchA:
undetectable
5g48A-3tchA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4c BACILYSIN
BIOSYNTHESIS
OXIDOREDUCTASE YWFH


(Bacillus
subtilis)
PF13561
(adh_short_C2)
4 THR A   5
LEU A  83
ILE A  76
LEU A 127
None
0.87A 5g48A-3u4cA:
undetectable
5g48A-3u4cA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ue1 PENICILLIN-BINDING
PROTEIN 1A


(Acinetobacter
baumannii)
PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB)
4 LEU A 150
ILE A 180
PRO A 192
LEU A 183
None
0.66A 5g48A-3ue1A:
undetectable
5g48A-3ue1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE


(Pachysandra
terminalis)
PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C)
4 THR A 109
LEU A 119
ILE A 173
LEU A 144
None
0.81A 5g48A-3uggA:
undetectable
5g48A-3uggA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE


(Pachysandra
terminalis)
PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C)
4 THR A 109
LEU A 119
ILE A 173
PRO A 147
None
0.89A 5g48A-3uggA:
undetectable
5g48A-3uggA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vot L-AMINO ACID LIGASE,
BL00235


(Bacillus
licheniformis)
PF13535
(ATP-grasp_4)
4 LEU A  56
ILE A  11
LEU A  54
MET A  64
None
0.83A 5g48A-3votA:
undetectable
5g48A-3votA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrh PUTATIVE
UNCHARACTERIZED
PROTEIN PH0300


(Pyrococcus
horikoshii)
PF01171
(ATP_bind_3)
4 THR A  45
ILE A  50
PRO A 195
LEU A  67
None
0.83A 5g48A-3vrhA:
undetectable
5g48A-3vrhA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az7 BETA-N-ACETYLHEXOSAM
INIDASE


(Streptococcus
pneumoniae)
PF00728
(Glyco_hydro_20)
4 THR A 567
THR A 611
PRO A 560
LEU A 563
None
0.90A 5g48A-4az7A:
undetectable
5g48A-4az7A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME


(unidentified)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 THR A 262
LEU A 281
ILE A 295
LEU A 279
None
0.87A 5g48A-4e4uA:
undetectable
5g48A-4e4uA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i34 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX


(Escherichia
coli)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small)
4 THR A 141
LEU A 165
ILE A 162
LEU A 166
None
0.95A 5g48A-4i34A:
undetectable
5g48A-4i34A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 LEU A 748
ILE A 726
PRO A 739
LEU A 744
None
0.92A 5g48A-4k33A:
undetectable
5g48A-4k33A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4maa PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN


(Pseudomonas
protegens)
PF13458
(Peripla_BP_6)
4 THR A 346
LEU A 288
ILE A 313
LEU A 292
None
0.97A 5g48A-4maaA:
undetectable
5g48A-4maaA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ns4 ALPHA/BETA HYDROLASE
FOLD PROTEIN


(Psychrobacter
cryohalolentis)
PF00561
(Abhydrolase_1)
4 LEU A 101
PRO A  43
ILE A  70
LEU A 100
None
0.92A 5g48A-4ns4A:
undetectable
5g48A-4ns4A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8m TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT


(Actinobacillus
succinogenes)
PF03480
(DctP)
4 LEU A 121
PRO A 238
ILE A 105
LEU A 120
None
0.95A 5g48A-4o8mA:
undetectable
5g48A-4o8mA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP


(Salmonella
enterica)
PF12468
(TTSSLRR)
PF14496
(NEL)
4 THR A 202
LEU A 204
ILE A 197
PRO A 240
None
0.80A 5g48A-4pufA:
undetectable
5g48A-4pufA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q0w DNA REPAIR PROTEIN
RAD2


(Saccharomyces
cerevisiae)
PF00752
(XPG_N)
PF00867
(XPG_I)
4 LEU A 779
PRO A  72
ILE A  62
LEU A 778
None
0.87A 5g48A-4q0wA:
undetectable
5g48A-4q0wA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r16 418AA LONG
HYPOTHETICAL
UDP-N-ACETYL-D-MANNO
SAMINURONIC ACID
DEHYDROGENASE


(Pyrococcus
horikoshii)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
4 LEU A  97
ILE A 120
PRO A  92
LEU A  94
None
0.80A 5g48A-4r16A:
undetectable
5g48A-4r16A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt7 RECEPTOR-TYPE
TYROSINE-PROTEIN
KINASE FLT3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 LEU A 943
ILE A 921
PRO A 934
LEU A 939
None
0.97A 5g48A-4rt7A:
undetectable
5g48A-4rt7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA


(Bacillus
subtilis)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 THR A 181
LEU A 186
PRO A 252
PRO A 359
None
0.73A 5g48A-4tr6A:
37.7
5g48A-4tr6A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzg SURFACE PROTEIN SPB1

(Streptococcus
agalactiae)
no annotation 4 THR A 418
LEU A 441
ILE A 354
LEU A 414
EDO  A1471 (-4.7A)
None
None
None
0.93A 5g48A-4uzgA:
undetectable
5g48A-4uzgA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wa0 POSSIBLE ADHESIN

(Caldicellulosiruptor
kronotskyensis)
no annotation 4 THR A 523
LEU A 524
ILE A 510
LEU A 526
None
0.70A 5g48A-4wa0A:
undetectable
5g48A-4wa0A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgt FRQ-INTERACTING RNA
HELICASE


(Neurospora
crassa)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch)
4 THR A 520
LEU A 517
ILE A 495
LEU A 514
None
0.74A 5g48A-4xgtA:
undetectable
5g48A-4xgtA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z2a FURIN

(Homo sapiens)
PF00082
(Peptidase_S8)
PF01483
(P_proprotein)
4 THR A 562
LEU A 493
ILE A 551
LEU A 491
None
0.94A 5g48A-4z2aA:
undetectable
5g48A-4z2aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a62 PUTATIVE ALPHA/BETA
HYDROLASE FOLD
PROTEIN


(Candidatus
Nitrososphaera
gargensis)
PF00561
(Abhydrolase_1)
4 LEU A  85
PRO A  25
ILE A  54
LEU A  84
None
0.80A 5g48A-5a62A:
undetectable
5g48A-5a62A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa5 NIFE-HYDROGENASE
LARGE SUBUNIT, HOFG
NIFE-HYDROGENASE
SMALL SUBUNIT, HOFK


(Cupriavidus
necator)
PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
4 THR A  27
ILE C  57
PRO A 100
LEU A  30
None
0.95A 5g48A-5aa5A:
undetectable
5g48A-5aa5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah4 DNA POLYMERASE III
SUBUNIT BETA


(Mycolicibacterium
smegmatis)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
6 THR A 179
LEU A 184
PRO A 257
PRO A 360
LEU A 389
MET A 391
None
0.50A 5g48A-5ah4A:
36.3
5g48A-5ah4A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b19 ASPARTATE RACEMASE

(Picrophilus
torridus)
PF01177
(Asp_Glu_race)
4 LEU A 184
ILE A 174
PRO A 146
LEU A 119
None
0.86A 5g48A-5b19A:
undetectable
5g48A-5b19A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b8f 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE


(Pseudomonas
aeruginosa)
PF02542
(YgbB)
4 LEU A  20
PRO A 103
ILE A  98
LEU A  40
None
0.88A 5g48A-5b8fA:
undetectable
5g48A-5b8fA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzz DESMOPLAKIN

(Homo sapiens)
PF00681
(Plectin)
4 PRO A2418
ILE A2263
PRO A2304
LEU A2443
None
0.87A 5g48A-5dzzA:
undetectable
5g48A-5dzzA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5


(Saccharomyces
cerevisiae)
PF12717
(Cnd1)
4 THR A 366
LEU A 363
ILE A 345
LEU A 359
None
0.86A 5g48A-5frsA:
undetectable
5g48A-5frsA:
21.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5g4q DNA POLYMERASE III
SUBUNIT BETA


(Helicobacter
pylori)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 THR A 173
LEU A 178
PRO A 243
LEU A 368
MET A 370
None
0.63A 5g48A-5g4qA:
49.9
5g48A-5g4qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5g4q DNA POLYMERASE III
SUBUNIT BETA


(Helicobacter
pylori)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
6 THR A 173
THR A 175
LEU A 178
PRO A 243
PRO A 347
LEU A 368
None
0.28A 5g48A-5g4qA:
49.9
5g48A-5g4qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h67 CHROMOSOME PARTITION
PROTEIN SMC


(Bacillus
subtilis)
PF02463
(SMC_N)
4 THR B1097
LEU B1101
ILE A 149
LEU B1102
None
0.87A 5g48A-5h67B:
undetectable
5g48A-5h67B:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2


(Mus musculus)
no annotation 4 THR A  65
ILE A  54
LEU A  70
MET A 125
None
0.92A 5g48A-5iwzA:
undetectable
5g48A-5iwzA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j47 LARGE T ANTIGEN

(Human
polyomavirus 2)
PF06431
(Polyoma_lg_T_C)
4 THR A 575
LEU A 443
ILE A 406
LEU A 440
None
0.92A 5g48A-5j47A:
undetectable
5g48A-5j47A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kom PUTATIVE FLUORIDE
ION TRANSPORTER CRCB


(Escherichia
coli)
PF02537
(CRCB)
4 THR A  70
LEU A  73
ILE A  47
LEU A  77
None
0.91A 5g48A-5komA:
undetectable
5g48A-5komA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3i RNASE III INHIBITOR

(Mycobacterium
tuberculosis)
PF01661
(Macro)
4 LEU A   9
PRO A 115
ILE A  31
LEU A  10
None
0.85A 5g48A-5m3iA:
undetectable
5g48A-5m3iA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN


(Campylobacter
jejuni)
PF05523
(FdtA)
4 LEU A  89
ILE A  69
LEU A  60
MET A  62
None
0.94A 5g48A-5tpuA:
undetectable
5g48A-5tpuA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u38 LECTIN

(Platypodium
elegans)
PF00139
(Lectin_legB)
4 THR A  26
LEU A  32
ILE A  51
LEU A 229
None
0.96A 5g48A-5u38A:
undetectable
5g48A-5u38A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7z DNA POLYMERASE III
SUBUNIT BETA


(Rickettsia
conorii)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 THR A 172
LEU A 177
PRO A 246
PRO A 359
MET A 375
MRD  A 403 (-3.1A)
MRD  A 403 ( 4.0A)
None
None
MRD  A 403 ( 4.5A)
0.68A 5g48A-5w7zA:
37.9
5g48A-5w7zA:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5weg UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE


(Saccharum
hybrid cultivar)
no annotation 4 THR A 369
LEU A 373
ILE A 401
LEU A 374
None
0.90A 5g48A-5wegA:
undetectable
5g48A-5wegA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wyp DNA POLYMERASE III
SUBUNIT BETA


(Caulobacter
vibrioides)
no annotation 4 THR A 177
LEU A 182
PRO A 248
PRO A 352
None
0.75A 5g48A-5wypA:
37.6
5g48A-5wypA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE


(Trichomonas
vaginalis)
PF00833
(Ribosomal_S17e)
4 THR R  55
LEU R  57
ILE R  17
LEU R  61
C  21198 ( 3.9A)
None
None
None
0.93A 5g48A-5xyiR:
undetectable
5g48A-5xyiR:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT


(Methylobacillus
sp. KY4400)
no annotation 4 THR B 107
LEU B  71
ILE B  50
LEU B  56
FAD  B 401 (-3.0A)
None
None
None
0.75A 5g48A-5y6qB:
undetectable
5g48A-5y6qB:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhu MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1


(Bos taurus)
no annotation 4 THR A 826
LEU A 824
ILE A 811
LEU A 791
None
0.91A 5g48A-6bhuA:
undetectable
5g48A-6bhuA:
0.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bx4 FLUORIDE ION
TRANSPORTER CRCB


(Escherichia
coli)
no annotation 4 THR A  70
LEU A  73
ILE A  47
LEU A  77
None
0.95A 5g48A-6bx4A:
undetectable
5g48A-6bx4A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d46 BETA SLIDING CLAMP

(Rickettsia
typhi)
no annotation 5 THR A 172
LEU A 177
PRO A 246
PRO A 361
MET A 377
None
0.45A 5g48A-6d46A:
38.6
5g48A-6d46A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d47 BETA SLIDING CLAMP

(Mycobacterium
marinum)
no annotation 5 LEU A 186
PRO A 259
PRO A 362
LEU A 394
MET A 396
None
0.64A 5g48A-6d47A:
36.9
5g48A-6d47A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d47 BETA SLIDING CLAMP

(Mycobacterium
marinum)
no annotation 5 THR A 181
LEU A 186
PRO A 259
LEU A 394
MET A 396
None
0.64A 5g48A-6d47A:
36.9
5g48A-6d47A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd6 PHOTOLYASE PHRB

(Agrobacterium
tumefaciens)
no annotation 4 THR A 162
LEU A 164
ILE A 304
LEU A 165
None
0.84A 5g48A-6dd6A:
undetectable
5g48A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6deg BETA SLIDING CLAMP

(Bartonella
birtlesii)
no annotation 4 THR A 177
LEU A 182
PRO A 353
MET A 369
None
0.75A 5g48A-6degA:
33.8
5g48A-6degA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dll P-HYDROXYBENZOATE
HYDROXYLASE


(Pseudomonas
putida)
no annotation 4 PRO A 275
ILE A 169
PRO A 129
LEU A 132
None
0.91A 5g48A-6dllA:
undetectable
5g48A-6dllA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftx -

(-)
no annotation 4 PRO W1201
ILE W 327
PRO W 287
LEU W 330
None
0.89A 5g48A-6ftxW:
undetectable
5g48A-6ftxW:
undetectable