SIMILAR PATTERNS OF AMINO ACIDS FOR 5FXT_A_0LAA1376_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bqg | D-GLUCARATEDEHYDRATASE (Pseudomonasputida) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 388THR A 358PRO A 398MET A 325 | None | 1.06A | 5fxtA-1bqgA:undetectable | 5fxtA-1bqgA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g38 | MODIFICATIONMETHYLASE TAQI (Thermusaquaticus) |
PF07669(Eco57I)PF12950(TaqI_C) | 4 | LYS A 149LEU A 153PRO A 95ILE A 86 | None | 1.03A | 5fxtA-1g38A:undetectable | 5fxtA-1g38A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i6a | HYDROGENPEROXIDE-INDUCIBLEGENES ACTIVATOR (Escherichiacoli) |
PF03466(LysR_substrate) | 4 | LEU A 224THR A 100PRO A 241LEU A 146 | None | 1.04A | 5fxtA-1i6aA:undetectable | 5fxtA-1i6aA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ni5 | PUTATIVE CELL CYCLEPROTEIN MESJ (Escherichiacoli) |
PF01171(ATP_bind_3)PF09179(TilS)PF11734(TilS_C) | 4 | LEU A 295PRO A 270ILE A 258LEU A 241 | None | 1.03A | 5fxtA-1ni5A:undetectable | 5fxtA-1ni5A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrj | SIGNAL RECOGNITIONPARTICLE RECEPTORBETA SUBUNIT (Saccharomycescerevisiae) |
PF09439(SRPRB) | 4 | LEU B 102THR B 139ILE B 149LEU B 217 | None | 0.88A | 5fxtA-1nrjB:undetectable | 5fxtA-1nrjB:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nu5 | CHLOROMUCONATECYCLOISOMERASE (Pseudomonas sp.P51) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 309THR A 305ILE A 325LEU A 299 | None | 0.95A | 5fxtA-1nu5A:undetectable | 5fxtA-1nu5A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q20 | SULFOTRANSFERASEFAMILY, CYTOSOLIC,2B, MEMBER 1 ISOFORMB (Homo sapiens) |
PF00685(Sulfotransfer_1) | 4 | LEU A 121ILE A 224LEU A 206MET A 145 | None | 0.91A | 5fxtA-1q20A:undetectable | 5fxtA-1q20A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5h | DUTP PYROPHOSPHATASE (Homo sapiens) |
PF00692(dUTPase) | 4 | LEU A 27THR A 45PRO A 15LEU A 8 | None | 1.04A | 5fxtA-1q5hA:undetectable | 5fxtA-1q5hA:14.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qua | ACUTOLYSIN-C (Deinagkistrodonacutus) |
PF01421(Reprolysin) | 4 | LEU A 197THR A 6PRO A 193LEU A 47 | None | 0.98A | 5fxtA-1quaA:undetectable | 5fxtA-1quaA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 4 | LEU A 351THR A 322ILE A 245LEU A 297 | None | 1.01A | 5fxtA-1rf5A:undetectable | 5fxtA-1rf5A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1seh | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Escherichiacoli) |
PF00692(dUTPase) | 4 | LEU A 33THR A 53PRO A 21LEU A 10 | None | 1.02A | 5fxtA-1sehA:undetectable | 5fxtA-1sehA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vft | ALANINE RACEMASE (Streptomyceslavendulae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | LEU A 238THR A 214PRO A 175ILE A 180 | None | 1.06A | 5fxtA-1vftA:undetectable | 5fxtA-1vftA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wuf | HYPOTHETICAL PROTEINLIN2664 (Listeriainnocua) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LYS A1027LEU A1026THR A1021PRO A1052 | None | 1.02A | 5fxtA-1wufA:undetectable | 5fxtA-1wufA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wxj | TRYPTOPHAN SYNTHASEALPHA CHAIN (Thermusthermophilus) |
PF00290(Trp_syntA) | 4 | LEU A 50THR A 98PRO A 102LEU A 128 | None | 1.06A | 5fxtA-1wxjA:undetectable | 5fxtA-1wxjA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zap | SECRETED ASPARTICPROTEINASE (Candidaalbicans) |
PF00026(Asp) | 4 | LEU A 306THR A 224ILE A 234LEU A 296 | None | 0.77A | 5fxtA-1zapA:undetectable | 5fxtA-1zapA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avt | DNA POLYMERASE IIIBETA SUBUNIT (Streptococcuspyogenes) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | LEU A 162THR A 180PRO A 250LEU A 371 | None | 0.42A | 5fxtA-2avtA:36.5 | 5fxtA-2avtA:26.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2awa | DNA POLYMERASE III,BETA CHAIN (Streptococcuspneumoniae) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | LEU A 162THR A 180PRO A 250LEU A 371 | None | 0.53A | 5fxtA-2awaA:36.7 | 5fxtA-2awaA:25.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2awg | 38 KDA FK-506BINDING PROTEIN (Homo sapiens) |
PF00254(FKBP_C) | 4 | LEU A 127THR A 129ILE A 188LEU A 131 | None | 1.04A | 5fxtA-2awgA:undetectable | 5fxtA-2awgA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dvu | THERMOPHILICREVERSIBLEGAMMA-RESORCYLATEDECARBOXYLASE (Rhizobium sp.MTP-10005) |
PF04909(Amidohydro_2) | 4 | LEU A 321PRO A 160ILE A 214LEU A 216 | None | 0.91A | 5fxtA-2dvuA:undetectable | 5fxtA-2dvuA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g9b | CALBINDIN (Rattusnorvegicus) |
PF13405(EF-hand_6)PF13499(EF-hand_7) | 4 | LYS A 133LEU A 130ILE A 118LEU A 151 | None | 1.06A | 5fxtA-2g9bA:undetectable | 5fxtA-2g9bA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jam | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE 1G (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 259PRO A 219ILE A 212LEU A 213 | None | 1.00A | 5fxtA-2jamA:undetectable | 5fxtA-2jamA:24.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jyz | CG7054-PA (Drosophilamelanogaster) |
PF01161(PBP) | 4 | LEU A 59THR A 57ILE A 125LEU A 55 | None | 0.98A | 5fxtA-2jyzA:undetectable | 5fxtA-2jyzA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qty | POLY(ADP-RIBOSE)GLYCOHYDROLASE ARH3 (Mus musculus) |
PF03747(ADP_ribosyl_GH) | 4 | LEU A 289THR A 288ILE A 309LEU A 269 | None | 1.05A | 5fxtA-2qtyA:undetectable | 5fxtA-2qtyA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzw | CANDIDAPEPSIN-1 (Candidaalbicans) |
PF00026(Asp) | 4 | LEU A 306THR A 224ILE A 234LEU A 296 | None | 0.78A | 5fxtA-2qzwA:undetectable | 5fxtA-2qzwA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkw | CARBOXYLESTERASE (Alcaligenes sp.) |
no annotation | 4 | LYS A 196LEU A 197THR A 200LEU A 203 | None | 1.06A | 5fxtA-2wkwA:undetectable | 5fxtA-2wkwA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x64 | GLUTATHIONE-S-TRANSFERASE (Xylellafastidiosa) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU A 116THR A 113LEU A 109MET A 105 | None | 0.97A | 5fxtA-2x64A:undetectable | 5fxtA-2x64A:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a8t | ADENYLATEISOPENTENYLTRANSFERASE (Humulus lupulus) |
PF01715(IPPT) | 4 | LEU A 197THR A 73ILE A 222MET A 64 | NoneNoneATP A 800 (-4.3A)ATP A 800 (-4.5A) | 0.98A | 5fxtA-3a8tA:undetectable | 5fxtA-3a8tA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfa | CALCIUM-DEPENDENTPROTEIN KINASECGD3_920 (Cryptosporidiumparvum) |
PF00069(Pkinase) | 4 | LEU A 244PRO A 204ILE A 197LEU A 198 | None | 1.03A | 5fxtA-3dfaA:undetectable | 5fxtA-3dfaA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehm | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF12741(SusD-like) | 4 | LEU A 462THR A 273PRO A 460LEU A 278 | None | 0.96A | 5fxtA-3ehmA:undetectable | 5fxtA-3ehmA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehw | DUTP PYROPHOSPHATASE (Homo sapiens) |
PF00692(dUTPase) | 4 | LEU A 50THR A 68PRO A 38LEU A 31 | None | 0.99A | 5fxtA-3ehwA:undetectable | 5fxtA-3ehwA:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejf | NON-STRUCTURALPROTEIN 3 (Aviancoronavirus) |
PF01661(Macro) | 4 | LEU A 127PRO A 125ILE A 53MET A 43 | None | 0.93A | 5fxtA-3ejfA:undetectable | 5fxtA-3ejfA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euc | HISTIDINOL-PHOSPHATEAMINOTRANSFERASE 2 (Cupriaviduspinatubonensis) |
PF00155(Aminotran_1_2) | 4 | LEU A 137PRO A 114ILE A 181LEU A 149 | None | 1.06A | 5fxtA-3eucA:undetectable | 5fxtA-3eucA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewo | NON-STRUCTURALPROTEIN 3 (Aviancoronavirus) |
PF01661(Macro) | 4 | LEU A 129PRO A 127ILE A 55MET A 45 | None | 0.92A | 5fxtA-3ewoA:undetectable | 5fxtA-3ewoA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g40 | NA-K-CLCOTRANSPORTER (Methanosarcinaacetivorans) |
no annotation | 4 | LYS A 740LEU A 715PRO A 709LEU A 633 | None | 1.07A | 5fxtA-3g40A:undetectable | 5fxtA-3g40A:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gaa | UNCHARACTERIZEDPROTEIN TA1441 (Thermoplasmaacidophilum) |
PF09754(PAC2) | 4 | LEU A 51THR A 50ILE A 203LEU A 219 | None | 0.98A | 5fxtA-3gaaA:undetectable | 5fxtA-3gaaA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ig3 | PLXNA3 PROTEIN (Mus musculus) |
PF08337(Plexin_cytopl) | 4 | LEU A1749THR A1745PRO A1733ILE A1739 | None | 1.01A | 5fxtA-3ig3A:undetectable | 5fxtA-3ig3A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igo | CALMODULIN-DOMAINPROTEIN KINASE 1 (Cryptosporidiumparvum) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | LEU A 313PRO A 273ILE A 266LEU A 267 | None | 0.98A | 5fxtA-3igoA:undetectable | 5fxtA-3igoA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8p | DSL1PROTEIN TRANSPORTPROTEIN SEC39 (Kluyveromyceslactis;Saccharomycescerevisiae) |
PF08314(Sec39)PF11989(Dsl1_C) | 4 | LYS C 460LEU C 463THR D 663LEU D 650 | None | 1.04A | 5fxtA-3k8pC:undetectable | 5fxtA-3k8pC:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lij | CALCIUM/CALMODULINDEPENDENT PROTEINKINASE WITH A KINASEDOMAIN AND 4CALMODULIN LIKE EFHANDS (Cryptosporidiumparvum) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | LEU A 299PRO A 259ILE A 252LEU A 253 | None | 0.96A | 5fxtA-3lijA:undetectable | 5fxtA-3lijA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lma | STAGE V SPORULATIONPROTEIN AD (SPOVAD) (Bacilluslicheniformis) |
PF07451(SpoVAD) | 4 | LEU A 235THR A 232ILE A 213LEU A 303 | None | 0.97A | 5fxtA-3lmaA:undetectable | 5fxtA-3lmaA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lqw | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Entamoebahistolytica) |
PF00692(dUTPase) | 4 | LEU A 29THR A 47PRO A 17LEU A 10 | None | 0.96A | 5fxtA-3lqwA:undetectable | 5fxtA-3lqwA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ma6 | CALMODULIN-DOMAINPROTEIN KINASE 1 (Toxoplasmagondii) |
PF00069(Pkinase) | 4 | LEU A 272PRO A 232ILE A 225LEU A 226 | None | 0.97A | 5fxtA-3ma6A:undetectable | 5fxtA-3ma6A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mc9 | ALR2269 PROTEIN (Nostoc sp. PCC7120) |
PF07244(POTRA)PF08479(POTRA_2) | 4 | LEU A 235THR A 236PRO A 295ILE A 332 | None | 0.98A | 5fxtA-3mc9A:undetectable | 5fxtA-3mc9A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdx | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Brucellaabortus) |
PF00692(dUTPase) | 4 | LEU A 37THR A 59PRO A 25LEU A 16 | None | 0.96A | 5fxtA-3mdxA:undetectable | 5fxtA-3mdxA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0w | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Ralstoniapickettii) |
PF13378(MR_MLE_C) | 4 | LEU A 399THR A 368PRO A 409MET A 335 | None | 1.04A | 5fxtA-3p0wA:undetectable | 5fxtA-3p0wA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 4 | LEU A 277THR A 219ILE A 216LEU A 245 | NoneBEZ A 701 (-4.0A)BEZ A 701 (-4.2A)None | 1.07A | 5fxtA-3r75A:undetectable | 5fxtA-3r75A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rb9 | DNA POLYMERASE IIISUBUNIT BETA (Mycobacteriumtuberculosis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | LEU A 164THR A 181PRO A 259LEU A 394MET A 396 | None | 1.00A | 5fxtA-3rb9A:36.2 | 5fxtA-3rb9A:25.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rfy | PEPTIDYL-PROLYLCIS-TRANS ISOMERASECYP38, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00160(Pro_isomerase) | 4 | THR A 270PRO A 384LEU A 234MET A 232 | None | 0.99A | 5fxtA-3rfyA:undetectable | 5fxtA-3rfyA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjt | LIPOLYTIC PROTEING-D-S-L FAMILY (Alicyclobacillusacidocaldarius) |
PF13472(Lipase_GDSL_2) | 4 | LEU A 138PRO A 194ILE A 202LEU A 133 | None | 1.04A | 5fxtA-3rjtA:undetectable | 5fxtA-3rjtA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ryt | PLEXIN-A1 (Mus musculus) |
PF08337(Plexin_cytopl) | 4 | LEU A1771THR A1767PRO A1755ILE A1761 | None | 1.05A | 5fxtA-3rytA:undetectable | 5fxtA-3rytA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4t | AMIDOHYDROLASE 2 (Polaromonas sp.JS666) |
PF04909(Amidohydro_2) | 4 | LEU A 321PRO A 160ILE A 214LEU A 216 | None | 0.87A | 5fxtA-3s4tA:undetectable | 5fxtA-3s4tA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3she | MAP KINASE-ACTIVATEDPROTEIN KINASE 3 (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 285PRO A 241ILE A 234LEU A 235 | None | 0.97A | 5fxtA-3sheA:undetectable | 5fxtA-3sheA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3so2 | PUTATIVEUNCHARACTERIZEDPROTEIN (Chlorellavariabilis) |
PF00692(dUTPase) | 4 | LEU A 31THR A 49PRO A 19LEU A 12 | None | 1.02A | 5fxtA-3so2A:undetectable | 5fxtA-3so2A:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqz | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Coxiellaburnetii) |
PF00692(dUTPase) | 4 | LEU A 33THR A 53PRO A 21LEU A 10 | None | 0.90A | 5fxtA-3tqzA:undetectable | 5fxtA-3tqzA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zgb | PHOSPHOENOLPYRUVATECARBOXYLASE (Flaveriapringlei) |
PF00311(PEPcase) | 4 | LEU A 79THR A 894ILE A 94MET A 101 | None | 1.02A | 5fxtA-3zgbA:undetectable | 5fxtA-3zgbA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9g | CS6 FIMBRIAL SUBUNITB, CS6 FIMBRIALSUBUNIT A (Escherichiacoli) |
PF16831(CssAB) | 4 | LEU A 38THR A 158PRO A 32ILE A 160 | None | 1.07A | 5fxtA-4b9gA:undetectable | 5fxtA-4b9gA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhl | ARGININE KINASE (Litopenaeusvannamei) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 4 | LEU A 159ILE A 230LEU A 246MET A 233 | None | 1.03A | 5fxtA-4bhlA:undetectable | 5fxtA-4bhlA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d1e | ALPHA-ACTININ-2 (Homo sapiens) |
PF00307(CH)PF00435(Spectrin)PF08726(EFhand_Ca_insen) | 4 | PRO A 240ILE A 245LEU A 186MET A 216 | MLZ A 239 ( 2.6A)NoneNoneNone | 1.05A | 5fxtA-4d1eA:undetectable | 5fxtA-4d1eA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6y | CITRATE SYNTHASE (Vibriovulnificus) |
PF00285(Citrate_synt) | 4 | LEU A 150PRO A 249ILE A 393LEU A 166 | None | 0.98A | 5fxtA-4e6yA:undetectable | 5fxtA-4e6yA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ezd | UREA TRANSPORTER 1 (Bos taurus) |
PF03253(UT) | 4 | LEU A 345THR A 341PRO A 169LEU A 287 | None | 0.95A | 5fxtA-4ezdA:undetectable | 5fxtA-4ezdA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f7a | PUTATIVEUNCHARACTERIZEDPROTEIN (Bacteroidesvulgatus) |
PF12741(SusD-like) | 4 | LEU A 476THR A 292PRO A 474LEU A 297 | None | 1.03A | 5fxtA-4f7aA:undetectable | 5fxtA-4f7aA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hn8 | D-GLUCARATEDEHYDRATASE (Pseudomonasmendocina) |
PF13378(MR_MLE_C) | 4 | LEU A 400THR A 369PRO A 410MET A 336 | None | 1.03A | 5fxtA-4hn8A:undetectable | 5fxtA-4hn8A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i2w | PROTEIN UNC-45 (Caenorhabditiselegans) |
PF11701(UNC45-central) | 4 | LEU A 756THR A 755ILE A 711LEU A 714 | None | 0.89A | 5fxtA-4i2wA:undetectable | 5fxtA-4i2wA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k05 | CONSERVEDHYPOTHETICALEXPORTED PROTEIN (Bacteroidesfragilis) |
PF07075(DUF1343) | 4 | LEU A 133PRO A 128ILE A 61LEU A 60 | None | 0.86A | 5fxtA-4k05A:undetectable | 5fxtA-4k05A:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lhr | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Burkholderiathailandensis) |
PF00692(dUTPase) | 4 | LEU A 29THR A 49PRO A 17LEU A 8 | None | 1.07A | 5fxtA-4lhrA:undetectable | 5fxtA-4lhrA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mag | SIALIC ACID BINDINGPROTEIN (Vibrio cholerae) |
PF03480(DctP) | 4 | LEU A 224THR A 220ILE A 62LEU A 60 | None | 0.77A | 5fxtA-4magA:undetectable | 5fxtA-4magA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ooq | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Arabidopsisthaliana) |
PF00692(dUTPase) | 4 | LEU A 53THR A 71PRO A 41LEU A 34 | None | 0.95A | 5fxtA-4ooqA:undetectable | 5fxtA-4ooqA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgj | CALCIUM-DEPENDENTPROTEIN KINASE 4 (Plasmodiumfalciparum) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | LEU A 309PRO A 269ILE A 262LEU A 263 | None | 1.00A | 5fxtA-4rgjA:undetectable | 5fxtA-4rgjA:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | LEU A 164THR A 181PRO A 252LEU A 373 | None | 0.63A | 5fxtA-4tr6A:37.9 | 5fxtA-4tr6A:27.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgm | MITOCHONDRIALRIBONUCLEASE PPROTEIN 3 (Homo sapiens) |
PF16953(PRORP) | 4 | LEU A 233PRO A 242ILE A 275LEU A 271 | None | 0.92A | 5fxtA-4xgmA:undetectable | 5fxtA-4xgmA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 4 | LYS A 255LEU A 253ILE A 269LEU A 213 | None | 1.06A | 5fxtA-4yeuA:undetectable | 5fxtA-4yeuA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ah4 | DNA POLYMERASE IIISUBUNIT BETA (Mycolicibacteriumsmegmatis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | LEU A 162THR A 179PRO A 257LEU A 389MET A 391 | None | 0.82A | 5fxtA-5ah4A:36.5 | 5fxtA-5ah4A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cr9 | ABC-TYPEFE3+-HYDROXAMATETRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Saccharomonosporaviridis) |
PF01497(Peripla_BP_2) | 4 | LEU A 276THR A 314ILE A 328LEU A 325 | None | 1.00A | 5fxtA-5cr9A:undetectable | 5fxtA-5cr9A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6h | CSUA/BCSUC (Acinetobacterbaumannii) |
PF00345(PapD_N)PF05229(SCPU) | 4 | LEU B 30ILE B 72LEU B 147MET A 114 | None | 0.98A | 5fxtA-5d6hB:undetectable | 5fxtA-5d6hB:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eco | JASMONIC ACID-AMIDOSYNTHETASE JAR1 (Arabidopsisthaliana) |
PF03321(GH3) | 4 | LYS A 265LEU A 266PRO A 189LEU A 206 | None | 0.97A | 5fxtA-5ecoA:undetectable | 5fxtA-5ecoA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqv | BIFUNCTIONAL2',3'-CYCLICNUCLEOTIDE2'-PHOSPHODIESTERASE/3'-NUCLEOTIDASEPERIPLASMICPRECURSOR PROTEIN (Yersinia pestis) |
PF00149(Metallophos) | 4 | LEU A 40THR A 37ILE A 67LEU A 35 | None | 1.01A | 5fxtA-5eqvA:undetectable | 5fxtA-5eqvA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f9k | DEOXYURIDINE5'-TRIPHOSPHATENUCLEOTIDOHYDROLASE (Dictyosteliumdiscoideum) |
PF00692(dUTPase) | 4 | LEU A 29THR A 47PRO A 17LEU A 10 | None | 0.85A | 5fxtA-5f9kA:undetectable | 5fxtA-5f9kA:17.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5g4q | DNA POLYMERASE IIISUBUNIT BETA (Helicobacterpylori) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | LEU A 154THR A 173PRO A 243LEU A 368MET A 370 | None | 0.55A | 5fxtA-5g4qA:51.1 | 5fxtA-5g4qA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ggy | IRON(III) ABCTRANSPORTER,PERIPLASMICIRON-COMPOUND-BINDING PROTEIN (Vibrio cholerae) |
PF01497(Peripla_BP_2) | 4 | LEU A 131PRO A 105ILE A 99LEU A 113 | None | 1.05A | 5fxtA-5ggyA:undetectable | 5fxtA-5ggyA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7w | VENOM5'-NUCLEOTIDASE (Naja atra) |
no annotation | 4 | THR A 177ILE A 158LEU A 140MET A 113 | None | 0.89A | 5fxtA-5h7wA:undetectable | 5fxtA-5h7wA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ig1 | CAMK/CAMK2 PROTEINKINASE (Salpingoecarosetta) |
PF00069(Pkinase) | 4 | LEU A 256PRO A 216ILE A 209MET A 121 | None | 1.08A | 5fxtA-5ig1A:undetectable | 5fxtA-5ig1A:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j7u | MAJOR CAPSID PROTEIN (Faustovirus) |
PF04451(Capsid_NCLDV) | 4 | LEU A 341THR A 343PRO A 122ILE A 125 | None | 1.05A | 5fxtA-5j7uA:undetectable | 5fxtA-5j7uA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jzx | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Mycobacteriumtuberculosis) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | LEU A 245THR A 26PRO A 128LEU A 72 | NoneFAD A 401 (-3.8A)FAD A 401 (-3.7A)FAD A 401 (-3.9A) | 0.97A | 5fxtA-5jzxA:undetectable | 5fxtA-5jzxA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k04 | UNCHARACTERIZEDPROTEIN (Candidaalbicans) |
PF09797(NatB_MDM20) | 4 | LEU A 422THR A 419ILE A 387LEU A 653 | None | 0.98A | 5fxtA-5k04A:undetectable | 5fxtA-5k04A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ksd | ATPASE 2, PLASMAMEMBRANE-TYPE (Arabidopsisthaliana) |
PF00122(E1-E2_ATPase)PF00690(Cation_ATPase_N)PF00702(Hydrolase) | 4 | LEU A 148THR A 132PRO A 163ILE A 156 | None | 0.99A | 5fxtA-5ksdA:undetectable | 5fxtA-5ksdA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mwc | GENETICALLY-ENCODEDGREEN CALCIUMINDICATOR NTNC (syntheticconstruct) |
no annotation | 4 | LEU D 291ILE D 62LEU D 143MET D 146 | NoneNoneNoneCR2 D 70 ( 4.4A) | 0.98A | 5fxtA-5mwcD:undetectable | 5fxtA-5mwcD:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 4 | LEU A 234ILE A 344LEU A 230MET A 201 | None | 1.06A | 5fxtA-5nd1A:undetectable | 5fxtA-5nd1A:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uz9 | CRISPR-ASSOCIATEDPROTEIN CSY1 (Pseudomonasaeruginosa) |
PF09611(Cas_Csy1) | 4 | LEU A 178PRO A 192ILE A 73LEU A 174 | U M 2 ( 4.3A) A M 3 ( 4.8A) A M 3 ( 4.3A) G M 5 ( 4.8A) | 1.06A | 5fxtA-5uz9A:undetectable | 5fxtA-5uz9A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1w | GLYCOSIDE HYDROLASE (Bacillushalodurans) |
PF03639(Glyco_hydro_81) | 4 | LEU A 452THR A 450PRO A 61MET A 519 | None | 0.86A | 5fxtA-5v1wA:undetectable | 5fxtA-5v1wA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vjy | DUTP PYROPHOSPHATASE (Naegleriafowleri) |
PF00692(dUTPase) | 4 | LEU A 31THR A 49PRO A 19LEU A 12 | None | 0.96A | 5fxtA-5vjyA:undetectable | 5fxtA-5vjyA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vnc | GLYCOGEN [STARCH]SYNTHASE ISOFORM 2 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 568PRO A 505ILE A 317MET A 474 | None | 1.06A | 5fxtA-5vncA:undetectable | 5fxtA-5vncA:11.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7z | DNA POLYMERASE IIISUBUNIT BETA (Rickettsiaconorii) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | LEU A 155THR A 172PRO A 246MET A 375 | NoneMRD A 403 (-3.1A)NoneMRD A 403 ( 4.5A) | 0.79A | 5fxtA-5w7zA:38.1 | 5fxtA-5w7zA:26.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvo | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
no annotation | 4 | LEU C 426THR C 424ILE C 498LEU C 501 | None | 1.03A | 5fxtA-5wvoC:undetectable | 5fxtA-5wvoC:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wyp | DNA POLYMERASE IIISUBUNIT BETA (Caulobactervibrioides) |
no annotation | 4 | LEU A 156THR A 177PRO A 248MET A 368 | None | 1.07A | 5fxtA-5wypA:37.9 | 5fxtA-5wypA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ams | BETA SLIDING CLAMP (Pseudomonasaeruginosa) |
no annotation | 4 | LEU A 155THR A 172PRO A 243MET A 363 | None | 0.61A | 5fxtA-6amsA:39.1 | 5fxtA-6amsA:24.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ap4 | DNA POLYMERASE IIISUBUNIT BETA (Acinetobacterbaumannii) |
no annotation | 4 | LEU A 159THR A 176PRO A 258MET A 378 | None | 0.55A | 5fxtA-6ap4A:37.7 | 5fxtA-6ap4A:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d46 | BETA SLIDING CLAMP (Rickettsiatyphi) |
no annotation | 4 | LEU A 155THR A 172PRO A 246MET A 377 | None | 0.77A | 5fxtA-6d46A:38.8 | 5fxtA-6d46A:11.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d47 | BETA SLIDING CLAMP (Mycobacteriummarinum) |
no annotation | 5 | LEU A 164THR A 181PRO A 259LEU A 394MET A 396 | None | 0.79A | 5fxtA-6d47A:37.3 | 5fxtA-6d47A:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 4 | LEU A 404PRO A 362ILE A 364LEU A 380 | None | 0.88A | 5fxtA-6d95A:undetectable | 5fxtA-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC8DNA-DIRECTED RNAPOLYMERASES I, II,AND III SUBUNITRPABC2 (Saccharomycescerevisiae) |
no annotation | 4 | LEU G 59THR F 96ILE F 130LEU F 94 | None | 1.08A | 5fxtA-6f42G:undetectable | 5fxtA-6f42G:12.64 |