SIMILAR PATTERNS OF AMINO ACIDS FOR 5FVQ_A_H4BA760

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)


(Lactobacillus
sp. 30A)
PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C)
4 VAL A 667
TRP A 673
PHE A 681
GLU A 649
None
1.33A 5fvqA-1c4kA:
0.0
5fvqB-1c4kA:
0.0
5fvqA-1c4kA:
19.07
5fvqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fhu O-SUCCINYLBENZOATE
SYNTHASE


(Escherichia
coli)
PF13378
(MR_MLE_C)
4 ARG A   2
VAL A  87
TRP A  66
GLU A  76
None
1.50A 5fvqA-1fhuA:
0.0
5fvqB-1fhuA:
0.0
5fvqA-1fhuA:
25.23
5fvqB-1fhuA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flg PROTEIN
(QUINOPROTEIN
ETHANOL
DEHYDROGENASE)


(Pseudomonas
aeruginosa)
PF01011
(PQQ)
PF13360
(PQQ_2)
4 VAL A  41
TRP A 521
PHE A 501
GLU A 519
None
1.32A 5fvqA-1flgA:
0.0
5fvqB-1flgA:
0.0
5fvqA-1flgA:
19.67
5fvqB-1flgA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kex NEUROPILIN-1

(Homo sapiens)
PF00754
(F5_F8_type_C)
4 ARG A 130
TRP A  97
PHE A 131
GLU A  95
None
1.42A 5fvqA-1kexA:
0.0
5fvqB-1kexA:
0.0
5fvqA-1kexA:
16.83
5fvqB-1kexA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kh2 ARGININOSUCCINATE
SYNTHETASE


(Thermus
thermophilus)
PF00764
(Arginosuc_synth)
4 ARG A 282
VAL A 226
PHE A 220
GLU A 222
None
1.32A 5fvqA-1kh2A:
0.0
5fvqB-1kh2A:
0.1
5fvqA-1kh2A:
22.65
5fvqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5j ACONITATE HYDRATASE
2


(Escherichia
coli)
PF00330
(Aconitase)
PF06434
(Aconitase_2_N)
PF11791
(Aconitase_B_N)
4 ARG A 340
TRP A 155
PHE A 156
GLU A 154
None
1.31A 5fvqA-1l5jA:
0.0
5fvqB-1l5jA:
0.0
5fvqA-1l5jA:
19.28
5fvqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhz METHANE
MONOOXYGENASE
HYDROXYLASE


(Methylosinus
trichosporium)
PF02332
(Phenol_Hydrox)
4 VAL D  28
TRP D  31
PHE D  35
GLU D 132
None
1.34A 5fvqA-1mhzD:
0.0
5fvqB-1mhzD:
0.0
5fvqA-1mhzD:
20.85
5fvqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mzb FERRIC UPTAKE
REGULATION PROTEIN


(Pseudomonas
aeruginosa)
PF01475
(FUR)
4 ARG A  69
VAL A  54
PHE A  79
GLU A  36
None
1.03A 5fvqA-1mzbA:
0.2
5fvqB-1mzbA:
0.5
5fvqA-1mzbA:
16.59
5fvqB-1mzbA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p9o PHOSPHOPANTOTHENOYLC
YSTEINE SYNTHETASE


(Homo sapiens)
PF04127
(DFP)
4 ARG A  65
VAL A 255
PHE A 230
GLU A 233
None
1.47A 5fvqA-1p9oA:
0.0
5fvqB-1p9oA:
0.0
5fvqA-1p9oA:
21.72
5fvqB-1p9oA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1j HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa)
PF09152
(DUF1937)
4 ARG A   2
VAL A  28
TRP A 110
PHE A 117
None
1.48A 5fvqA-1t1jA:
undetectable
5fvqB-1t1jA:
undetectable
5fvqA-1t1jA:
16.38
5fvqB-1t1jA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vmk PURINE NUCLEOSIDE
PHOSPHORYLASE


(Thermotoga
maritima)
PF01048
(PNP_UDP_1)
4 VAL A 221
TRP A 162
PHE A 265
GLU A 161
None
1.45A 5fvqA-1vmkA:
undetectable
5fvqB-1vmkA:
undetectable
5fvqA-1vmkA:
21.48
5fvqB-1vmkA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wql ETHYLBENZENE
DIOXYGENASE SMALL
SUBUNIT


(Pseudomonas
fluorescens)
PF00866
(Ring_hydroxyl_B)
4 ARG B 156
VAL B 128
PHE B 163
GLU B  26
None
1.14A 5fvqA-1wqlB:
undetectable
5fvqB-1wqlB:
undetectable
5fvqA-1wqlB:
19.79
5fvqB-1wqlB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus)
PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
4 ARG A 708
VAL A1424
PHE A 722
GLU A 693
None
1.10A 5fvqA-2b39A:
undetectable
5fvqB-2b39A:
undetectable
5fvqA-2b39A:
13.58
5fvqB-2b39A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ciy CHLOROPEROXIDASE

(Leptoxyphium
fumago)
PF01328
(Peroxidase_2)
4 ARG A  50
VAL A  92
PHE A  76
GLU A  80
None
1.44A 5fvqA-2ciyA:
undetectable
5fvqB-2ciyA:
undetectable
5fvqA-2ciyA:
20.52
5fvqB-2ciyA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1


(Thermotoga
maritima)
PF02127
(Peptidase_M18)
4 ARG A 261
VAL A 443
PHE A  21
GLU A  17
None
1.25A 5fvqA-2glfA:
undetectable
5fvqB-2glfA:
undetectable
5fvqA-2glfA:
20.82
5fvqB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vy0 ENDO-BETA-1,3-GLUCAN
ASE


(Pyrococcus
furiosus)
PF00722
(Glyco_hydro_16)
4 VAL A 245
TRP A 252
PHE A 254
GLU A 251
None
None
None
MRD  A1301 (-4.3A)
1.41A 5fvqA-2vy0A:
undetectable
5fvqB-2vy0A:
undetectable
5fvqA-2vy0A:
20.00
5fvqB-2vy0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4o CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE IV


(Homo sapiens)
PF00069
(Pkinase)
4 ARG A 278
VAL A 269
TRP A 266
PHE A 261
None
1.45A 5fvqA-2w4oA:
undetectable
5fvqB-2w4oA:
undetectable
5fvqA-2w4oA:
20.26
5fvqB-2w4oA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA


(Escherichia
coli)
PF00232
(Glyco_hydro_1)
4 ARG A 159
VAL A 164
PHE A  98
GLU A 108
None
1.49A 5fvqA-2xhyA:
undetectable
5fvqB-2xhyA:
0.1
5fvqA-2xhyA:
20.63
5fvqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywb GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]


(Thermus
thermophilus)
PF00117
(GATase)
PF00958
(GMP_synt_C)
4 ARG A 211
VAL A 239
PHE A 309
GLU A 305
None
1.34A 5fvqA-2ywbA:
undetectable
5fvqB-2ywbA:
undetectable
5fvqA-2ywbA:
21.54
5fvqB-2ywbA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z11 RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE


(Thermus
thermophilus)
PF13302
(Acetyltransf_3)
4 VAL A  64
TRP A  66
PHE A   4
GLU A   6
None
1.41A 5fvqA-2z11A:
undetectable
5fvqB-2z11A:
undetectable
5fvqA-2z11A:
17.58
5fvqB-2z11A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b7f GLYCOSYL HYDROLASE,
BNR REPEAT


(Cupriavidus
pinatubonensis)
no annotation 4 VAL A 314
TRP A 293
TRP A 374
GLU A 372
None
None
None
EDO  A 404 ( 3.8A)
1.41A 5fvqA-3b7fA:
undetectable
5fvqB-3b7fA:
undetectable
5fvqA-3b7fA:
20.87
5fvqB-3b7fA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddl XANTHORHODOPSIN

(Salinibacter
ruber)
PF01036
(Bac_rhodopsin)
4 VAL A  16
TRP A  70
PHE A  88
GLU A  71
None
1.50A 5fvqA-3ddlA:
undetectable
5fvqB-3ddlA:
undetectable
5fvqA-3ddlA:
20.14
5fvqB-3ddlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gs3 SYMPLEKIN

(Drosophila
melanogaster)
PF11935
(DUF3453)
4 ARG A  27
VAL A  56
PHE A  67
GLU A  65
None
1.47A 5fvqA-3gs3A:
undetectable
5fvqB-3gs3A:
undetectable
5fvqA-3gs3A:
20.28
5fvqB-3gs3A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l3p IPAH9.8

(Shigella
flexneri)
PF14496
(NEL)
4 VAL A 258
TRP A 261
TRP A 274
GLU A 314
None
1.32A 5fvqA-3l3pA:
undetectable
5fvqB-3l3pA:
undetectable
5fvqA-3l3pA:
20.60
5fvqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ma6 CALMODULIN-DOMAIN
PROTEIN KINASE 1


(Toxoplasma
gondii)
PF00069
(Pkinase)
4 ARG A 269
VAL A 260
TRP A 257
PHE A 252
None
1.44A 5fvqA-3ma6A:
undetectable
5fvqB-3ma6A:
undetectable
5fvqA-3ma6A:
21.55
5fvqB-3ma6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o98 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE


(Escherichia
coli)
PF03738
(GSP_synth)
PF05257
(CHAP)
4 ARG A  64
VAL A 132
PHE A  75
GLU A  83
TS5  A 620 (-2.3A)
None
None
None
1.17A 5fvqA-3o98A:
undetectable
5fvqB-3o98A:
undetectable
5fvqA-3o98A:
20.85
5fvqB-3o98A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owc PROBABLE
ACETYLTRANSFERASE


(Pseudomonas
aeruginosa)
PF00583
(Acetyltransf_1)
4 ARG A 175
VAL A  92
PHE A 121
GLU A 119
None
1.24A 5fvqA-3owcA:
undetectable
5fvqB-3owcA:
undetectable
5fvqA-3owcA:
16.47
5fvqB-3owcA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjy ENDOGLUCANASE
FNCEL5A


(Fervidobacterium
nodosum)
PF00150
(Cellulase)
4 VAL A 149
TRP A 146
PHE A 162
GLU A 187
None
1.27A 5fvqA-3rjyA:
undetectable
5fvqB-3rjyA:
undetectable
5fvqA-3rjyA:
21.27
5fvqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti8 NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
4 VAL A 240
TRP A 239
PHE A 305
GLU A 265
None
1.45A 5fvqA-3ti8A:
undetectable
5fvqB-3ti8A:
undetectable
5fvqA-3ti8A:
22.64
5fvqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1


(Schizosaccharomyces
pombe)
no annotation 4 ARG B 924
VAL B 944
PHE B 953
GLU B 951
None
1.36A 5fvqA-3tixB:
undetectable
5fvqB-3tixB:
undetectable
5fvqA-3tixB:
21.73
5fvqB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqu NON-CANONICAL PURINE
NTP PYROPHOSPHATASE


(Coxiella
burnetii)
PF01725
(Ham1p_like)
4 VAL A 162
TRP A 140
PHE A 118
GLU A 141
None
1.27A 5fvqA-3tquA:
undetectable
5fvqB-3tquA:
undetectable
5fvqA-3tquA:
19.05
5fvqB-3tquA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgd PRE-MRNA-SPLICING
FACTOR 8


(Saccharomyces
cerevisiae)
PF08084
(PROCT)
4 VAL C2274
TRP C2314
PHE C2329
GLU C2310
None
1.31A 5fvqA-4bgdC:
undetectable
5fvqB-4bgdC:
undetectable
5fvqA-4bgdC:
20.99
5fvqB-4bgdC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnq ALPHA-GALACTOSIDASE
AGAB


(Geobacillus
stearothermophilus)
PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N)
4 ARG A 373
VAL A 412
TRP A 383
PHE A 370
None
1.45A 5fvqA-4fnqA:
undetectable
5fvqB-4fnqA:
undetectable
5fvqA-4fnqA:
20.73
5fvqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmv GLUTATHIONE
TRANSFERASE


(Phanerochaete
chrysosporium)
PF13417
(GST_N_3)
4 ARG A  29
VAL A  73
PHE A   7
GLU A  42
None
FLC  A 300 (-4.1A)
None
None
1.11A 5fvqA-4lmvA:
undetectable
5fvqB-4lmvA:
undetectable
5fvqA-4lmvA:
21.00
5fvqB-4lmvA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pne METHYLTRANSFERASE-LI
KE PROTEIN


(Saccharopolyspora
spinosa)
PF08241
(Methyltransf_11)
4 ARG A  75
VAL A  79
PHE A 141
GLU A 162
None
1.41A 5fvqA-4pneA:
undetectable
5fvqB-4pneA:
undetectable
5fvqA-4pneA:
21.36
5fvqB-4pneA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ras OXIDOREDUCTASE,
NAD-BINDING/IRON-SUL
FUR CLUSTER-BINDING
PROTEIN


(Nitratireductor
pacificus)
PF12838
(Fer4_7)
PF13486
(Dehalogenase)
4 ARG A 424
TRP A 613
PHE A  89
GLU A 406
None
1.48A 5fvqA-4rasA:
undetectable
5fvqB-4rasA:
undetectable
5fvqA-4rasA:
19.02
5fvqB-4rasA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj6 VC0179-LIKE PROTEIN

(Escherichia
coli)
no annotation 4 ARG A 276
VAL A 305
PHE A 264
GLU A 266
None
1.10A 5fvqA-4xj6A:
undetectable
5fvqB-4xj6A:
undetectable
5fvqA-4xj6A:
21.06
5fvqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj6 VC0179-LIKE PROTEIN

(Escherichia
coli)
no annotation 4 VAL A 305
TRP A 263
PHE A 264
GLU A 266
None
1.09A 5fvqA-4xj6A:
undetectable
5fvqB-4xj6A:
undetectable
5fvqA-4xj6A:
21.06
5fvqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ylr TUBULIN
POLYGLUTAMYLASE
TTLL7


(Homo sapiens)
PF03133
(TTL)
4 VAL A 288
TRP A 292
PHE A 277
GLU A 279
None
1.41A 5fvqA-4ylrA:
undetectable
5fvqB-4ylrA:
undetectable
5fvqA-4ylrA:
22.81
5fvqB-4ylrA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4x REELIN

(Mus musculus)
PF07974
(EGF_2)
4 VAL A2595
TRP A2641
TRP A2654
PHE A2555
None
1.45A 5fvqA-5b4xA:
undetectable
5fvqB-5b4xA:
undetectable
5fvqA-5b4xA:
19.36
5fvqB-5b4xA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by3 BTGH115A

(Bacteroides
thetaiotaomicron)
PF15979
(Glyco_hydro_115)
4 ARG A 505
VAL A 736
TRP A 732
GLU A 731
None
1.35A 5fvqA-5by3A:
undetectable
5fvqB-5by3A:
undetectable
5fvqA-5by3A:
19.82
5fvqB-5by3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjn L-AMINO ACID
DEAMINASE


(Cosenzaea
myxofaciens)
PF01266
(DAO)
4 ARG A 316
VAL A 438
TRP A 439
GLU A 418
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
1.32A 5fvqA-5fjnA:
undetectable
5fvqB-5fjnA:
undetectable
5fvqA-5fjnA:
23.27
5fvqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m8t 5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE


(Homo sapiens)
PF00264
(Tyrosinase)
4 ARG A 225
TRP A 414
PHE A 411
GLU A 413
None
1.05A 5fvqA-5m8tA:
undetectable
5fvqB-5m8tA:
undetectable
5fvqA-5m8tA:
20.00
5fvqB-5m8tA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xf7 PROTEIN
DISULFIDE-ISOMERASE-
LIKE PROTEIN OF THE
TESTIS


(Homo sapiens)
no annotation 4 ARG A 129
VAL A  65
PHE A 113
GLU A 106
None
1.17A 5fvqA-5xf7A:
undetectable
5fvqB-5xf7A:
undetectable
5fvqA-5xf7A:
10.85
5fvqB-5xf7A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bk1 UDP-GLYCOSYLTRANSFER
ASE 79


(Oryza sativa)
no annotation 4 ARG A 331
VAL A 317
TRP A 316
GLU A 322
None
UDP  A 501 ( 4.8A)
None
None
1.31A 5fvqA-6bk1A:
undetectable
5fvqB-6bk1A:
undetectable
5fvqA-6bk1A:
13.48
5fvqB-6bk1A:
13.48