SIMILAR PATTERNS OF AMINO ACIDS FOR 5FUQ_B_ACTB1276

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al2 DNA TOPOISOMERASE
2-BINDING PROTEIN 1

(Homo sapiens) 		PF00533
(BRCT) 		4 TYR A1318
HIS A1311
SER A1274
GLN A1367
 None
None
SO4  A   1 (-4.7A)
None
 1.50A 5fuqA-3al2A:
0.0
5fuqB-3al2A:
0.0		 5fuqA-3al2A:
21.51
5fuqB-3al2A:
21.51