SIMILAR PATTERNS OF AMINO ACIDS FOR 5FSA_B_X2NB590_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a04 | NITRATE/NITRITERESPONSE REGULATORPROTEIN NARL (Escherichiacoli) |
PF00072(Response_reg)PF00196(GerE) | 5 | GLY A 21GLN A 24LEU A 55GLY A 126PHE A 86 | None | 1.23A | 5fsaB-1a04A:undetectable | 5fsaB-1a04A:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ao0 | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Bacillussubtilis) |
PF00156(Pribosyltran)PF13522(GATase_6) | 5 | GLY A 27GLN A 24LEU A 180ILE A 216HIS A 70 | None | 1.18A | 5fsaB-1ao0A:undetectable | 5fsaB-1ao0A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hc7 | PROLYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 5 | TYR A 182GLY A 227GLN A 225PHE A 236GLY A 117 | None | 1.08A | 5fsaB-1hc7A:0.0 | 5fsaB-1hc7A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg8 | ENDOPOLYGALACTURONASE (Fusariumverticillioides) |
PF00295(Glyco_hydro_28) | 6 | TYR A 112GLY A 109GLN A 110LEU A 58PHE A 71ILE A 95 | None | 1.41A | 5fsaB-1hg8A:0.0 | 5fsaB-1hg8A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1x | 4-ALPHA-GLUCANOTRANSFERASE (Thermococcuslitoralis) |
PF03065(Glyco_hydro_57)PF09094(DUF1925)PF09095(DUF1926) | 5 | GLY A 52PHE A 238PHE A 34ILE A 241HIS A 49 | None | 1.19A | 5fsaB-1k1xA:0.0 | 5fsaB-1k1xA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6u | TRYPTOPHANYL-TRNASYNTHETASE (Homo sapiens) |
PF00579(tRNA-synt_1b) | 5 | GLY A 265LEU A 103PHE A 138ILE A 136PHE A 84 | None | 1.18A | 5fsaB-1r6uA:0.0 | 5fsaB-1r6uA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rw9 | CHONDROITIN AC LYASE (Paenarthrobacteraurescens) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | GLY A 481TYR A 626ILE A 450GLY A 422HIS A 376 | None | 1.16A | 5fsaB-1rw9A:undetectable | 5fsaB-1rw9A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s58 | B19 PARVOVIRUSCAPSID (Primateerythroparvovirus1) |
PF00740(Parvo_coat) | 5 | TYR A 161GLN A 451PHE A 99PHE A 492ILE A 108 | None | 1.26A | 5fsaB-1s58A:undetectable | 5fsaB-1s58A:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3q | QUINOLINE2-OXIDOREDUCTASELARGE SUBUNITQUINOLINE2-OXIDOREDUCTASESMALL SUBUNIT (Pseudomonasputida) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | GLY B 509GLN B 508LEU B 27ILE A 121HIS A 103 | MCN B4921 ( 4.3A)MCN B4921 (-3.8A)NoneNoneNone | 1.28A | 5fsaB-1t3qB:2.0 | 5fsaB-1t3qB:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 5 | TYR A 374GLY A 373PHE A 215GLY A 163THR A 165 | NoneNoneNH3 A 402 (-3.4A)NoneNone | 1.16A | 5fsaB-1u7gA:undetectable | 5fsaB-1u7gA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6s | METHANOLDEHYDROGENASESUBUNIT 1 (Methylobacteriumextorquens) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | GLY A 428GLN A 429LEU A 129ILE A 517GLY A 539 | NoneNoneNoneNonePQQ A1596 (-3.5A) | 1.05A | 5fsaB-1w6sA:undetectable | 5fsaB-1w6sA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdw | TRYPTOPHAN SYNTHASEALPHA CHAINTRYPTOPHAN SYNTHASEBETA CHAIN 1 (Pyrococcusfuriosus) |
PF00290(Trp_syntA)PF00291(PALP) | 5 | GLY A 111PHE B 274PHE A 41GLY B 287PHE A 125 | None | 1.22A | 5fsaB-1wdwA:undetectable | 5fsaB-1wdwA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x9e | HMG-COA SYNTHASE (Enterococcusfaecalis) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 5 | TYR A 227LEU A 281TYR A 112ILE A 75PHE A 314 | None | 1.18A | 5fsaB-1x9eA:undetectable | 5fsaB-1x9eA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahn | THAUMATIN-LIKEPROTEIN (Prunus avium) |
PF00314(Thaumatin) | 5 | GLY A 213LEU A 41PHE A 31PHE A 5GLY A 16 | None | 1.28A | 5fsaB-2ahnA:undetectable | 5fsaB-2ahnA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3t | FATTY OXIDATIONCOMPLEX ALPHASUBUNIT (Pseudomonasfragi) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | GLY A 392LEU A 412PHE A 447GLY A 449THR A 478 | None | 1.21A | 5fsaB-2d3tA:undetectable | 5fsaB-2d3tA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d62 | MULTIPLESUGAR-BINDINGTRANSPORTATP-BINDING PROTEIN (Pyrococcushorikoshii) |
PF00005(ABC_tran)PF08402(TOBE_2) | 5 | GLY A 291LEU A 331PHE A 342THR A 303PHE A 266 | None | 1.23A | 5fsaB-2d62A:undetectable | 5fsaB-2d62A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e0p | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF12891(Glyco_hydro_44) | 5 | TYR A 362LEU A 355ILE A 227GLY A 229PHE A 381 | None | 1.12A | 5fsaB-2e0pA:undetectable | 5fsaB-2e0pA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e5v | L-ASPARTATE OXIDASE (Sulfurisphaeratokodaii) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | GLY A 374LEU A 203ILE A 189GLY A 190THR A 172 | NoneNoneNoneNoneFAD A1002 (-4.1A) | 1.18A | 5fsaB-2e5vA:undetectable | 5fsaB-2e5vA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9y | CARBAMATE KINASE (Aeropyrumpernix) |
PF00696(AA_kinase) | 5 | GLY A 196GLN A 86LEU A 232GLY A 296THR A 236 | None | 1.13A | 5fsaB-2e9yA:undetectable | 5fsaB-2e9yA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gq3 | MALATE SYNTHASE G (Mycobacteriumtuberculosis) |
PF01274(Malate_synthase) | 5 | TYR A 555GLN A 557ILE A 639THR A 517HIS A 551 | None | 1.23A | 5fsaB-2gq3A:undetectable | 5fsaB-2gq3A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9k | MODIFICATIONMETHYLASE HHAI (Haemophilushaemolyticus) |
PF00145(DNA_methylase) | 5 | GLY A 158LEU A 251TYR A 299ILE A 207GLY A 264 | None | 1.22A | 5fsaB-2i9kA:undetectable | 5fsaB-2i9kA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ich | PUTATIVE ATTH (Nitrosomonaseuropaea) |
PF07143(CrtC)PF17186(Lipocalin_9) | 5 | GLY A 171PHE A 333GLY A 343THR A 53PHE A 244 | NoneNoneNoneNoneNHE A 1 (-3.6A) | 1.28A | 5fsaB-2ichA:undetectable | 5fsaB-2ichA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odl | ADHESIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 5 | GLY A 166GLN A 145LEU A 233GLY A 216THR A 171 | None | 1.19A | 5fsaB-2odlA:undetectable | 5fsaB-2odlA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p24 | H-2 CLASS IIHISTOCOMPATIBILITYANTIGEN, A-U ALPHACHAINH-2 CLASS IIHISTOCOMPATIBILITYANTIGEN, A-U BETACHAIN (Mus musculus) |
PF00969(MHC_II_beta)PF00993(MHC_II_alpha)PF07654(C1-set) | 5 | GLY B 1TYR A 133PHE A 138ILE A 106GLY B 251 | None | 1.29A | 5fsaB-2p24B:undetectable | 5fsaB-2p24B:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4q | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING 1 (Saccharomycescerevisiae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLY A 129PHE A 394TYR A 379PHE A 371HIS A 185 | FLC A 502 ( 4.5A)NoneNoneNoneFLC A 502 (-4.5A) | 1.11A | 5fsaB-2p4qA:undetectable | 5fsaB-2p4qA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qiw | PEP PHOSPHONOMUTASE (Corynebacteriumglutamicum) |
PF13714(PEP_mutase) | 5 | GLY A 228LEU A 23PHE A 11ILE A 101GLY A 108 | GOL A 259 (-3.6A)NoneNoneNoneNone | 1.04A | 5fsaB-2qiwA:undetectable | 5fsaB-2qiwA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 5 | GLY A 152GLN A 153LEU A 181ILE A 169GLY A 167 | None | 1.25A | 5fsaB-2qjpA:0.0 | 5fsaB-2qjpA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qmi | PBP RELATEDBETA-LACTAMASE (Pyrococcusabyssi) |
PF00144(Beta-lactamase)PF13969(Pab87_oct) | 5 | TYR A 284ILE A 215GLY A 307THR A 310HIS A 302 | None | 1.29A | 5fsaB-2qmiA:undetectable | 5fsaB-2qmiA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rau | PUTATIVE ESTERASE (Sulfolobussolfataricus) |
PF12146(Hydrolase_4) | 5 | GLY A 154LEU A 329ILE A 217GLY A 211PHE A 304 | NoneNone CA A 354 ( 3.9A)NoneNone | 1.20A | 5fsaB-2rauA:undetectable | 5fsaB-2rauA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v6o | THIOREDOXINGLUTATHIONEREDUCTASE (Schistosomamansoni) |
PF00462(Glutaredoxin)PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | TYR A 212GLY A 151PHE A 474ILE A 547GLY A 545 | None | 1.28A | 5fsaB-2v6oA:undetectable | 5fsaB-2v6oA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v8j | PECTATE LYASE (Yersiniaenterocolitica) |
PF06917(Pectate_lyase_2) | 5 | LEU A 131TYR A 135PHE A 156THR A 169PHE A 513 | None | 1.28A | 5fsaB-2v8jA:undetectable | 5fsaB-2v8jA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vtc | CEL61B (Trichodermareesei) |
PF03443(Glyco_hydro_61) | 5 | PHE A 211TYR A 214ILE A 123GLY A 92HIS A 1 | NoneNoneNoneNone NI A1231 (-3.2A) | 1.16A | 5fsaB-2vtcA:undetectable | 5fsaB-2vtcA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w8z | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING (Geobacillusstearothermophilus) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLY A 129PHE A 394TYR A 379PHE A 371HIS A 185 | 6PG A1470 (-3.7A)NoneNoneNone6PG A1470 (-4.5A) | 1.10A | 5fsaB-2w8zA:undetectable | 5fsaB-2w8zA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4g | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE (Pseudomonasaeruginosa) |
PF01370(Epimerase) | 5 | TYR A 54PHE A 333GLY A 194THR A 192HIS A 26 | None | 1.10A | 5fsaB-2x4gA:undetectable | 5fsaB-2x4gA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yd0 | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | GLY A 676GLN A 675LEU A 686GLY A 920PHE A 699 | None | 0.90A | 5fsaB-2yd0A:undetectable | 5fsaB-2yd0A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zyg | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING (Klebsiellapneumoniae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLY A 129PHE A 393TYR A 378PHE A 370HIS A 186 | None | 1.16A | 5fsaB-2zygA:undetectable | 5fsaB-2zygA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aw5 | MULTICOPPER OXIDASE (Pyrobaculumaerophilum) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 463PHE A 143ILE A 173GLY A 225HIS A 396 | NoneNoneNoneNoneC2O A 702 ( 3.3A) | 1.23A | 5fsaB-3aw5A:undetectable | 5fsaB-3aw5A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bb7 | INTERPAIN A (Prevotellaintermedia) |
PF01640(Peptidase_C10)PF13734(Inhibitor_I69) | 5 | GLY A 292LEU A 163TYR A 199PHE A 259GLY A 258 | None | 1.19A | 5fsaB-3bb7A:undetectable | 5fsaB-3bb7A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3be8 | NEUROLIGIN-4,X-LINKED (Homo sapiens) |
PF00135(COesterase) | 5 | LEU A 132PHE A 128ILE A 172GLY A 174HIS A 113 | NoneNoneNonePO4 A 623 ( 3.6A)None | 1.25A | 5fsaB-3be8A:undetectable | 5fsaB-3be8A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c9f | 5'-NUCLEOTIDASE (Candidaalbicans) |
PF00149(Metallophos) | 5 | GLN A 125LEU A 177ILE A 220GLY A 247THR A 33 | None | 1.14A | 5fsaB-3c9fA:undetectable | 5fsaB-3c9fA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9t | L-TYROSINEDECARBOXYLASE MFNA (Methanocaldococcusjannaschii) |
PF00282(Pyridoxal_deC) | 5 | GLY A 288LEU A 298PHE A 216ILE A 214GLY A 211 | None | 1.23A | 5fsaB-3f9tA:undetectable | 5fsaB-3f9tA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcj | NITROALKANE OXIDASE (Fusariumoxysporum) |
PF00441(Acyl-CoA_dh_1)PF02771(Acyl-CoA_dh_N) | 5 | GLY A 267GLN A 266ILE A 285GLY A 281THR A 358 | None | 0.95A | 5fsaB-3fcjA:undetectable | 5fsaB-3fcjA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdg | DIPEPTIDASE AC.METALLO PEPTIDASE.MEROPS FAMILY M19 (Rhodobactersphaeroides) |
PF01244(Peptidase_M19) | 6 | GLY A 313LEU A 38PHE A 53PHE A 48ILE A 133GLY A 51 | None | 1.41A | 5fsaB-3fdgA:undetectable | 5fsaB-3fdgA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgw | PUTATIVEPHOSPHOLIPASE B-LIKE2 (Mus musculus) |
PF04916(Phospholip_B) | 5 | GLY A 377GLN A 408LEU A 168GLY A 218PHE A 163 | None | 1.15A | 5fsaB-3fgwA:undetectable | 5fsaB-3fgwA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw6 | CELLULASE (unculturedbacterium) |
PF12891(Glyco_hydro_44) | 5 | GLY A 272GLN A 280LEU A 310GLY A 250PHE A 325 | None | 1.06A | 5fsaB-3fw6A:undetectable | 5fsaB-3fw6A:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hy8 | PYRIDOXINE-5'-PHOSPHATE OXIDASE (Homo sapiens) |
PF01243(Putative_PNPOx)PF10590(PNP_phzG_C) | 5 | GLY A 144GLN A 214LEU A 149TYR A 157PHE A 109 | NoneNoneNonePO4 A 360 (-3.7A)None | 1.24A | 5fsaB-3hy8A:undetectable | 5fsaB-3hy8A:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzd | IRON-CONTAININGALCOHOLDEHYDROGENASE (Cupriaviduspinatubonensis) |
PF00465(Fe-ADH) | 5 | GLY A 249LEU A 166GLY A 96THR A 100HIS A 71 | NoneNoneNoneNoneNAD A 400 (-3.4A) | 1.24A | 5fsaB-3jzdA:undetectable | 5fsaB-3jzdA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mda | DNA POLYMERASELAMBDA (Homo sapiens) |
PF10391(DNA_pol_lambd_f)PF14716(HHH_8)PF14791(DNA_pol_B_thumb)PF14792(DNA_pol_B_palm) | 5 | GLY A 508LEU A 532GLY A 524THR A 522PHE A 560 | None | 1.25A | 5fsaB-3mdaA:undetectable | 5fsaB-3mdaA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0h | GLUTATHIONEREDUCTASE (Bartonellahenselae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | TYR A 99GLY A 40PHE A 345ILE A 414GLY A 412 | None | 1.07A | 5fsaB-3o0hA:undetectable | 5fsaB-3o0hA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0r | NITRIC OXIDEREDUCTASE SUBUNIT B (Pseudomonasaeruginosa) |
PF00115(COX1) | 5 | GLY B 408GLN B 411PHE B 261ILE B 254GLY B 257 | None | 1.04A | 5fsaB-3o0rB:undetectable | 5fsaB-3o0rB:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9t | CHOLINEDEHYDROGENASE ANDRELATEDFLAVOPROTEINS (Aspergillusoryzae) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | GLY A 402LEU A 97GLY A 211THR A 203PHE A 512 | NoneFAY A 600 (-4.9A)NoneNoneFAY A 600 (-3.6A) | 1.25A | 5fsaB-3q9tA:undetectable | 5fsaB-3q9tA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjo | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF11838(ERAP1_C) | 5 | GLY A 676GLN A 675LEU A 686GLY A 920PHE A 699 | None | 0.94A | 5fsaB-3rjoA:undetectable | 5fsaB-3rjoA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 5 | GLY M 413GLN M 416LEU M 272ILE M 83GLY M 85 | None | 1.19A | 5fsaB-3rkoM:undetectable | 5fsaB-3rkoM:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tnl | SHIKIMATEDEHYDROGENASE (Listeriamonocytogenes) |
PF08501(Shikimate_dh_N) | 5 | GLY A 269GLN A 268LEU A 15PHE A 48PHE A 36 | NoneSKM A 293 (-3.3A)NoneNoneNone | 1.22A | 5fsaB-3tnlA:undetectable | 5fsaB-3tnlA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u1h | 3-ISOPROPYLMALATEDEHYDROGENASE (Bacillus sp.(in: Bacteria)) |
PF00180(Iso_dh) | 5 | GLY A 309TYR A 40GLY A 72THR A 296PHE A 36 | None | 0.95A | 5fsaB-3u1hA:undetectable | 5fsaB-3u1hA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsy | SORTILIN-RELATEDRECEPTOR (Homo sapiens) |
PF15901(Sortilin_C)PF15902(Sortilin-Vps10) | 5 | GLY A 238LEU A 231PHE A 284ILE A 293THR A 263 | None | 1.11A | 5fsaB-3wsyA:undetectable | 5fsaB-3wsyA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 5 | PHE A 380TYR A 197GLY A 249THR A 522PHE A 110 | None | 1.22A | 5fsaB-4ainA:undetectable | 5fsaB-4ainA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bob | ERPP PROTEIN (Borreliellaburgdorferi) |
PF02471(OspE) | 5 | LEU A 52PHE A 77ILE A 121GLY A 138THR A 150 | None | 1.18A | 5fsaB-4bobA:undetectable | 5fsaB-4bobA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ha4 | BETA-GALACTOSIDASE (Acidilobussaccharovorans) |
PF00232(Glyco_hydro_1) | 5 | GLY A 261ILE A 165GLY A 175THR A 181PHE A 291 | None | 1.28A | 5fsaB-4ha4A:undetectable | 5fsaB-4ha4A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j4b | PYLD (Methanosarcinabarkeri) |
no annotation | 5 | LEU A 101PHE A 63PHE A 108THR A 125PHE A 76 | None0TF A 904 (-3.8A)NoneNAI A 901 (-3.4A)None | 1.18A | 5fsaB-4j4bA:undetectable | 5fsaB-4j4bA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8p | FLAVODOXIN (Bacteroidesuniformis) |
PF12682(Flavodoxin_4) | 5 | GLY A 36PHE A 126TYR A 99PHE A 120PHE A 53 | GOL A 206 ( 3.3A)NoneGOL A 203 (-4.7A)NoneNone | 1.22A | 5fsaB-4j8pA:undetectable | 5fsaB-4j8pA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcs | ENOYL-COAHYDRATASE/ISOMERASE (Cupriavidusmetallidurans) |
PF00378(ECH_1) | 5 | GLY A 13LEU A 115PHE A 26ILE A 83GLY A 86 | None | 1.18A | 5fsaB-4jcsA:undetectable | 5fsaB-4jcsA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oua | PROTEOLYTICALLYACTIVATED FORM OFPPO4 TYROSINASE (Agaricusbisporus) |
PF00264(Tyrosinase) | 5 | GLY A 135LEU A 205ILE A 263GLY A 265THR A 268 | None | 1.27A | 5fsaB-4ouaA:0.4 | 5fsaB-4ouaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psw | HISTONEACETYLTRANSFERASETYPE B CATALYTICSUBUNITHISTONEACETYLTRANSFERASETYPE B SUBUNIT 2HISTONE H4 TYPE VIII (Ophiophagushannah;Saccharomycescerevisiae) |
PF00400(WD40)PF00583(Acetyltransf_1)PF10394(Hat1_N)PF12265(CAF1C_H4-bd)no annotation | 5 | TYR A 194GLY C 11LEU B 278PHE B 303GLY B 309 | None | 1.23A | 5fsaB-4pswA:undetectable | 5fsaB-4pswA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxn | UNCHARACTERIZEDPROTEIN (Zea mays) |
PF00171(Aldedh) | 5 | GLY A 270GLN A 423LEU A 343PHE A 352GLY A 370 | None | 1.25A | 5fsaB-4pxnA:undetectable | 5fsaB-4pxnA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tlv | ADP-RIBOSYLATINGTOXIN CARDS (Mycoplasmapneumoniae) |
PF02917(Pertussis_S1) | 5 | LEU A 403ILE A 280GLY A 279THR A 285PHE A 315 | None | 1.26A | 5fsaB-4tlvA:undetectable | 5fsaB-4tlvA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tpn | PUTATIVE P450-LIKEPROTEIN (Streptomycesscabiei) |
PF00067(p450) | 5 | GLY A 226LEU A 239TYR A 199GLY A 156THR A 215 | None | 1.28A | 5fsaB-4tpnA:26.6 | 5fsaB-4tpnA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uy6 | HISTIDINE-SPECIFICMETHYLTRANSFERASEEGTD (Mycolicibacteriumsmegmatis) |
PF10017(Methyltransf_33) | 5 | GLY A 25LEU A 167PHE A 159PHE A 142GLY A 86 | NoneNoneNoneSAH A 801 (-3.4A)SAH A 801 (-3.0A) | 1.01A | 5fsaB-4uy6A:undetectable | 5fsaB-4uy6A:21.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uym | 14-ALPHA STEROLDEMETHYLASE (Aspergillusfumigatus) |
PF00067(p450) | 5 | LEU A 125PHE A 130TYR A 136PHE A 229HIS A 374 | NoneVOR A 590 (-4.6A)HEM A 580 (-4.6A)NoneNone | 1.20A | 5fsaB-4uymA:51.5 | 5fsaB-4uymA:50.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uym | 14-ALPHA STEROLDEMETHYLASE (Aspergillusfumigatus) |
PF00067(p450) | 6 | TYR A 68GLY A 69LEU A 125PHE A 130TYR A 136HIS A 374 | NoneNoneNoneVOR A 590 (-4.6A)HEM A 580 (-4.6A)None | 1.01A | 5fsaB-4uymA:51.5 | 5fsaB-4uymA:50.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzs | ECU04_1440 PROTEINSIMILARITY TOHELICASE MOT1 (Encephalitozooncuniculi) |
PF00352(TBP)no annotation | 5 | GLY C 93GLN C 95LEU D 104PHE C 213ILE C 293 | None | 1.10A | 5fsaB-4wzsC:undetectable | 5fsaB-4wzsC:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8r | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Rhodobactersphaeroides) |
PF03480(DctP) | 5 | GLY A 192PHE A 131PHE A 93ILE A 137THR A 78 | None | 1.27A | 5fsaB-4x8rA:undetectable | 5fsaB-4x8rA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yxt | POLYKETIDEBIOSYNTHESIS3-HYDROXY-3-METHYLGLUTARYL-ACP SYNTHASEPKSG (Bacillussubtilis) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 5 | LEU A 302TYR A 115PHE A 303ILE A 78PHE A 334 | None | 1.04A | 5fsaB-4yxtA:undetectable | 5fsaB-4yxtA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | TYR A 875GLY A 876GLN A 485ILE A 395PHE A 737 | None | 1.24A | 5fsaB-5chcA:undetectable | 5fsaB-5chcA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfw | SINGLE CHAIN FVFRAGMENT (Mus musculus) |
PF07686(V-set) | 5 | TYR H 602GLN H 604ILE H 308THR H 124PHE H 753 | None | 1.29A | 5fsaB-5dfwH:undetectable | 5fsaB-5dfwH:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ee0 | OBG-LIKE ATPASE 1 (Oryza sativa) |
PF01926(MMR_HSR1)PF06071(YchF-GTPase_C) | 5 | GLY A 19LEU A 90PHE A 123THR A 258HIS A 303 | None | 1.25A | 5fsaB-5ee0A:undetectable | 5fsaB-5ee0A:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey7 | FRUCTOKINASE (Vibrio cholerae) |
PF00294(PfkB) | 5 | GLY A 307LEU A 80PHE A 63GLY A 65PHE A 75 | NA A 401 (-4.3A)NoneNoneNoneNone | 1.25A | 5fsaB-5ey7A:undetectable | 5fsaB-5ey7A:21.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 5 | TYR A 72GLY A 73GLY A 315THR A 318HIS A 381 | NoneNoneHEM A 601 (-3.5A)HEM A 601 (-3.4A)None | 0.86A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 9 | TYR A 72GLY A 73LEU A 129PHE A 134TYR A 140GLY A 314THR A 318HIS A 381PHE A 384 | NoneNoneNoneVOR A 602 (-4.7A)HEM A 601 (-4.3A)VOR A 602 (-3.0A)HEM A 601 (-3.4A)NoneNone | 0.62A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 6 | TYR A 72GLY A 73TYR A 140ILE A 471HIS A 381PHE A 384 | NoneNoneHEM A 601 (-4.3A)HEM A 601 ( 4.9A)NoneNone | 1.50A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 9 | TYR A 72LEU A 129PHE A 134TYR A 140PHE A 236GLY A 314THR A 318HIS A 381PHE A 384 | NoneNoneVOR A 602 (-4.7A)HEM A 601 (-4.3A)VOR A 602 (-4.4A)VOR A 602 (-3.0A)HEM A 601 (-3.4A)NoneNone | 0.64A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hst | POLYKETIDE SYNTHASETYPE I (Bacillusamyloliquefaciens) |
PF14765(PS-DH) | 5 | GLY A 222LEU A 284PHE A 213ILE A 59GLY A 56 | None | 1.18A | 5fsaB-5hstA:undetectable | 5fsaB-5hstA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huu | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE[UDP-FORMING] (Candidaalbicans) |
PF00982(Glyco_transf_20) | 5 | GLY A 406GLN A 409PHE A 463ILE A 139GLY A 167 | None | 1.10A | 5fsaB-5huuA:undetectable | 5fsaB-5huuA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvm | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Aspergillusfumigatus) |
PF00982(Glyco_transf_20) | 5 | GLY A 413GLN A 416PHE A 470ILE A 147GLY A 175 | None | 1.10A | 5fsaB-5hvmA:undetectable | 5fsaB-5hvmA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvo | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Aspergillusfumigatus) |
PF00982(Glyco_transf_20) | 5 | GLY A 413GLN A 416PHE A 470ILE A 146GLY A 175 | None | 1.16A | 5fsaB-5hvoA:undetectable | 5fsaB-5hvoA:22.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 5 | LEU A 130TYR A 127PHE A 237GLY A 315THR A 319 | None1YN A 602 ( 3.8A)1YN A 602 (-4.5A)1YN A 602 ( 3.6A)HEM A 601 ( 3.5A) | 1.26A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 5 | TYR A 73GLY A 74GLY A 316THR A 319HIS A 382 | 1YN A 602 (-4.9A)1YN A 602 ( 3.8A)HEM A 601 (-3.5A)HEM A 601 ( 3.5A)1YN A 602 (-4.2A) | 1.04A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 10 | TYR A 73GLY A 74LEU A 130PHE A 135TYR A 141PHE A 237GLY A 315THR A 319HIS A 382PHE A 385 | 1YN A 602 (-4.9A)1YN A 602 ( 3.8A)None1YN A 602 ( 4.6A)HEM A 601 (-4.2A)1YN A 602 (-4.5A)1YN A 602 ( 3.6A)HEM A 601 ( 3.5A)1YN A 602 (-4.2A)1YN A 602 (-4.8A) | 0.68A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 6 | TYR A 73GLY A 74TYR A 141ILE A 473HIS A 382PHE A 385 | 1YN A 602 (-4.9A)1YN A 602 ( 3.8A)HEM A 601 (-4.2A)HEM A 601 (-4.7A)1YN A 602 (-4.2A)1YN A 602 (-4.8A) | 1.39A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 5 | TYR B 247PHE B 106PHE B 76ILE B 461GLY B 227 | None | 1.29A | 5fsaB-5kohB:undetectable | 5fsaB-5kohB:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kov | PL-2 SCFV CHAIN (Mus musculus) |
PF07686(V-set) | 5 | GLY C1057PHE C 27ILE C 51GLY C 33HIS C1055 | None | 1.20A | 5fsaB-5kovC:undetectable | 5fsaB-5kovC:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ktz | VHH 12B (Camelusdromedarius) |
PF07686(V-set) | 5 | GLY 7 15GLN 7 13LEU 7 20GLY 7 115PHE 7 68 | None | 1.24A | 5fsaB-5ktz7:undetectable | 5fsaB-5ktz7:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgz | 8-DEMETHYLNOVOBIOCICACIDC(8)-METHYLTRANSFERASE (Streptomycesniveus) |
PF13649(Methyltransf_25) | 5 | GLY A 34LEU A 66PHE A 92GLY A 51PHE A 61 | None | 1.02A | 5fsaB-5mgzA:undetectable | 5fsaB-5mgzA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ols | RHAMNOGALACTURONANLYASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | GLY A 57LEU A 47TYR A 67PHE A 129ILE A 144 | None | 1.07A | 5fsaB-5olsA:undetectable | 5fsaB-5olsA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5osn | CAPSID PROTEIN (Enterovirus E) |
PF00073(Rhv) | 5 | LEU B 166PHE C 218ILE C 215THR B 119PHE B 156 | None | 1.24A | 5fsaB-5osnB:undetectable | 5fsaB-5osnB:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3f | TUBULIN ALPHA-1CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | GLY A 135GLN A 134LEU A 379ILE A 292PHE A 170 | None | 1.19A | 5fsaB-5w3fA:undetectable | 5fsaB-5w3fA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y4k | DMSP LYASE DDDY (Acinetobacterbereziniae) |
no annotation | 5 | GLY A 345GLN A 348PHE A 332ILE A 270THR A 357 | None | 1.14A | 5fsaB-5y4kA:undetectable | 5fsaB-5y4kA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zb3 | - (-) |
no annotation | 5 | TYR A 452LEU A 376PHE A 335PHE A 326THR A 436 | None | 1.08A | 5fsaB-5zb3A:undetectable | 5fsaB-5zb3A:undetectable |