SIMILAR PATTERNS OF AMINO ACIDS FOR 5FSA_B_X2NB590
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a04 | NITRATE/NITRITERESPONSE REGULATORPROTEIN NARL (Escherichiacoli) |
PF00072(Response_reg)PF00196(GerE) | 5 | GLY A 21GLN A 24LEU A 55GLY A 126PHE A 86 | None | 1.23A | 5fsaB-1a04A:undetectable | 5fsaB-1a04A:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ao0 | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Bacillussubtilis) |
PF00156(Pribosyltran)PF13522(GATase_6) | 5 | GLY A 27GLN A 24LEU A 180ILE A 216HIS A 70 | None | 1.18A | 5fsaB-1ao0A:undetectable | 5fsaB-1ao0A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hc7 | PROLYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 5 | TYR A 182GLY A 227GLN A 225PHE A 236GLY A 117 | None | 1.08A | 5fsaB-1hc7A:0.0 | 5fsaB-1hc7A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg8 | ENDOPOLYGALACTURONASE (Fusariumverticillioides) |
PF00295(Glyco_hydro_28) | 6 | TYR A 112GLY A 109GLN A 110LEU A 58PHE A 71ILE A 95 | None | 1.41A | 5fsaB-1hg8A:0.0 | 5fsaB-1hg8A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1x | 4-ALPHA-GLUCANOTRANSFERASE (Thermococcuslitoralis) |
PF03065(Glyco_hydro_57)PF09094(DUF1925)PF09095(DUF1926) | 5 | GLY A 52PHE A 238PHE A 34ILE A 241HIS A 49 | None | 1.19A | 5fsaB-1k1xA:0.0 | 5fsaB-1k1xA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6u | TRYPTOPHANYL-TRNASYNTHETASE (Homo sapiens) |
PF00579(tRNA-synt_1b) | 5 | GLY A 265LEU A 103PHE A 138ILE A 136PHE A 84 | None | 1.18A | 5fsaB-1r6uA:0.0 | 5fsaB-1r6uA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rw9 | CHONDROITIN AC LYASE (Paenarthrobacteraurescens) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | GLY A 481TYR A 626ILE A 450GLY A 422HIS A 376 | None | 1.16A | 5fsaB-1rw9A:undetectable | 5fsaB-1rw9A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s58 | B19 PARVOVIRUSCAPSID (Primateerythroparvovirus1) |
PF00740(Parvo_coat) | 5 | TYR A 161GLN A 451PHE A 99PHE A 492ILE A 108 | None | 1.26A | 5fsaB-1s58A:undetectable | 5fsaB-1s58A:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3q | QUINOLINE2-OXIDOREDUCTASELARGE SUBUNITQUINOLINE2-OXIDOREDUCTASESMALL SUBUNIT (Pseudomonasputida) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | GLY B 509GLN B 508LEU B 27ILE A 121HIS A 103 | MCN B4921 ( 4.3A)MCN B4921 (-3.8A)NoneNoneNone | 1.28A | 5fsaB-1t3qB:2.0 | 5fsaB-1t3qB:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 5 | TYR A 374GLY A 373PHE A 215GLY A 163THR A 165 | NoneNoneNH3 A 402 (-3.4A)NoneNone | 1.16A | 5fsaB-1u7gA:undetectable | 5fsaB-1u7gA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6s | METHANOLDEHYDROGENASESUBUNIT 1 (Methylobacteriumextorquens) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | GLY A 428GLN A 429LEU A 129ILE A 517GLY A 539 | NoneNoneNoneNonePQQ A1596 (-3.5A) | 1.05A | 5fsaB-1w6sA:undetectable | 5fsaB-1w6sA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdw | TRYPTOPHAN SYNTHASEALPHA CHAINTRYPTOPHAN SYNTHASEBETA CHAIN 1 (Pyrococcusfuriosus) |
PF00290(Trp_syntA)PF00291(PALP) | 5 | GLY A 111PHE B 274PHE A 41GLY B 287PHE A 125 | None | 1.22A | 5fsaB-1wdwA:undetectable | 5fsaB-1wdwA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x9e | HMG-COA SYNTHASE (Enterococcusfaecalis) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 5 | TYR A 227LEU A 281TYR A 112ILE A 75PHE A 314 | None | 1.18A | 5fsaB-1x9eA:undetectable | 5fsaB-1x9eA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahn | THAUMATIN-LIKEPROTEIN (Prunus avium) |
PF00314(Thaumatin) | 5 | GLY A 213LEU A 41PHE A 31PHE A 5GLY A 16 | None | 1.28A | 5fsaB-2ahnA:undetectable | 5fsaB-2ahnA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3t | FATTY OXIDATIONCOMPLEX ALPHASUBUNIT (Pseudomonasfragi) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | GLY A 392LEU A 412PHE A 447GLY A 449THR A 478 | None | 1.21A | 5fsaB-2d3tA:undetectable | 5fsaB-2d3tA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d62 | MULTIPLESUGAR-BINDINGTRANSPORTATP-BINDING PROTEIN (Pyrococcushorikoshii) |
PF00005(ABC_tran)PF08402(TOBE_2) | 5 | GLY A 291LEU A 331PHE A 342THR A 303PHE A 266 | None | 1.23A | 5fsaB-2d62A:undetectable | 5fsaB-2d62A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e0p | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF12891(Glyco_hydro_44) | 5 | TYR A 362LEU A 355ILE A 227GLY A 229PHE A 381 | None | 1.12A | 5fsaB-2e0pA:undetectable | 5fsaB-2e0pA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e5v | L-ASPARTATE OXIDASE (Sulfurisphaeratokodaii) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | GLY A 374LEU A 203ILE A 189GLY A 190THR A 172 | NoneNoneNoneNoneFAD A1002 (-4.1A) | 1.18A | 5fsaB-2e5vA:undetectable | 5fsaB-2e5vA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9y | CARBAMATE KINASE (Aeropyrumpernix) |
PF00696(AA_kinase) | 5 | GLY A 196GLN A 86LEU A 232GLY A 296THR A 236 | None | 1.13A | 5fsaB-2e9yA:undetectable | 5fsaB-2e9yA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gq3 | MALATE SYNTHASE G (Mycobacteriumtuberculosis) |
PF01274(Malate_synthase) | 5 | TYR A 555GLN A 557ILE A 639THR A 517HIS A 551 | None | 1.23A | 5fsaB-2gq3A:undetectable | 5fsaB-2gq3A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9k | MODIFICATIONMETHYLASE HHAI (Haemophilushaemolyticus) |
PF00145(DNA_methylase) | 5 | GLY A 158LEU A 251TYR A 299ILE A 207GLY A 264 | None | 1.22A | 5fsaB-2i9kA:undetectable | 5fsaB-2i9kA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ich | PUTATIVE ATTH (Nitrosomonaseuropaea) |
PF07143(CrtC)PF17186(Lipocalin_9) | 5 | GLY A 171PHE A 333GLY A 343THR A 53PHE A 244 | NoneNoneNoneNoneNHE A 1 (-3.6A) | 1.28A | 5fsaB-2ichA:undetectable | 5fsaB-2ichA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odl | ADHESIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 5 | GLY A 166GLN A 145LEU A 233GLY A 216THR A 171 | None | 1.19A | 5fsaB-2odlA:undetectable | 5fsaB-2odlA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p24 | H-2 CLASS IIHISTOCOMPATIBILITYANTIGEN, A-U ALPHACHAINH-2 CLASS IIHISTOCOMPATIBILITYANTIGEN, A-U BETACHAIN (Mus musculus) |
PF00969(MHC_II_beta)PF00993(MHC_II_alpha)PF07654(C1-set) | 5 | GLY B 1TYR A 133PHE A 138ILE A 106GLY B 251 | None | 1.29A | 5fsaB-2p24B:undetectable | 5fsaB-2p24B:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4q | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING 1 (Saccharomycescerevisiae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLY A 129PHE A 394TYR A 379PHE A 371HIS A 185 | FLC A 502 ( 4.5A)NoneNoneNoneFLC A 502 (-4.5A) | 1.11A | 5fsaB-2p4qA:undetectable | 5fsaB-2p4qA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qiw | PEP PHOSPHONOMUTASE (Corynebacteriumglutamicum) |
PF13714(PEP_mutase) | 5 | GLY A 228LEU A 23PHE A 11ILE A 101GLY A 108 | GOL A 259 (-3.6A)NoneNoneNoneNone | 1.04A | 5fsaB-2qiwA:undetectable | 5fsaB-2qiwA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 5 | GLY A 152GLN A 153LEU A 181ILE A 169GLY A 167 | None | 1.25A | 5fsaB-2qjpA:0.0 | 5fsaB-2qjpA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qmi | PBP RELATEDBETA-LACTAMASE (Pyrococcusabyssi) |
PF00144(Beta-lactamase)PF13969(Pab87_oct) | 5 | TYR A 284ILE A 215GLY A 307THR A 310HIS A 302 | None | 1.29A | 5fsaB-2qmiA:undetectable | 5fsaB-2qmiA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rau | PUTATIVE ESTERASE (Sulfolobussolfataricus) |
PF12146(Hydrolase_4) | 5 | GLY A 154LEU A 329ILE A 217GLY A 211PHE A 304 | NoneNone CA A 354 ( 3.9A)NoneNone | 1.20A | 5fsaB-2rauA:undetectable | 5fsaB-2rauA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v6o | THIOREDOXINGLUTATHIONEREDUCTASE (Schistosomamansoni) |
PF00462(Glutaredoxin)PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | TYR A 212GLY A 151PHE A 474ILE A 547GLY A 545 | None | 1.28A | 5fsaB-2v6oA:undetectable | 5fsaB-2v6oA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v8j | PECTATE LYASE (Yersiniaenterocolitica) |
PF06917(Pectate_lyase_2) | 5 | LEU A 131TYR A 135PHE A 156THR A 169PHE A 513 | None | 1.28A | 5fsaB-2v8jA:undetectable | 5fsaB-2v8jA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vtc | CEL61B (Trichodermareesei) |
PF03443(Glyco_hydro_61) | 5 | PHE A 211TYR A 214ILE A 123GLY A 92HIS A 1 | NoneNoneNoneNone NI A1231 (-3.2A) | 1.16A | 5fsaB-2vtcA:undetectable | 5fsaB-2vtcA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w8z | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING (Geobacillusstearothermophilus) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLY A 129PHE A 394TYR A 379PHE A 371HIS A 185 | 6PG A1470 (-3.7A)NoneNoneNone6PG A1470 (-4.5A) | 1.10A | 5fsaB-2w8zA:undetectable | 5fsaB-2w8zA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4g | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE (Pseudomonasaeruginosa) |
PF01370(Epimerase) | 5 | TYR A 54PHE A 333GLY A 194THR A 192HIS A 26 | None | 1.10A | 5fsaB-2x4gA:undetectable | 5fsaB-2x4gA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yd0 | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | GLY A 676GLN A 675LEU A 686GLY A 920PHE A 699 | None | 0.90A | 5fsaB-2yd0A:undetectable | 5fsaB-2yd0A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zyg | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING (Klebsiellapneumoniae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLY A 129PHE A 393TYR A 378PHE A 370HIS A 186 | None | 1.16A | 5fsaB-2zygA:undetectable | 5fsaB-2zygA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aw5 | MULTICOPPER OXIDASE (Pyrobaculumaerophilum) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 463PHE A 143ILE A 173GLY A 225HIS A 396 | NoneNoneNoneNoneC2O A 702 ( 3.3A) | 1.23A | 5fsaB-3aw5A:undetectable | 5fsaB-3aw5A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bb7 | INTERPAIN A (Prevotellaintermedia) |
PF01640(Peptidase_C10)PF13734(Inhibitor_I69) | 5 | GLY A 292LEU A 163TYR A 199PHE A 259GLY A 258 | None | 1.19A | 5fsaB-3bb7A:undetectable | 5fsaB-3bb7A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3be8 | NEUROLIGIN-4,X-LINKED (Homo sapiens) |
PF00135(COesterase) | 5 | LEU A 132PHE A 128ILE A 172GLY A 174HIS A 113 | NoneNoneNonePO4 A 623 ( 3.6A)None | 1.25A | 5fsaB-3be8A:undetectable | 5fsaB-3be8A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c9f | 5'-NUCLEOTIDASE (Candidaalbicans) |
PF00149(Metallophos) | 5 | GLN A 125LEU A 177ILE A 220GLY A 247THR A 33 | None | 1.14A | 5fsaB-3c9fA:undetectable | 5fsaB-3c9fA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9t | L-TYROSINEDECARBOXYLASE MFNA (Methanocaldococcusjannaschii) |
PF00282(Pyridoxal_deC) | 5 | GLY A 288LEU A 298PHE A 216ILE A 214GLY A 211 | None | 1.23A | 5fsaB-3f9tA:undetectable | 5fsaB-3f9tA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcj | NITROALKANE OXIDASE (Fusariumoxysporum) |
PF00441(Acyl-CoA_dh_1)PF02771(Acyl-CoA_dh_N) | 5 | GLY A 267GLN A 266ILE A 285GLY A 281THR A 358 | None | 0.95A | 5fsaB-3fcjA:undetectable | 5fsaB-3fcjA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdg | DIPEPTIDASE AC.METALLO PEPTIDASE.MEROPS FAMILY M19 (Rhodobactersphaeroides) |
PF01244(Peptidase_M19) | 6 | GLY A 313LEU A 38PHE A 53PHE A 48ILE A 133GLY A 51 | None | 1.41A | 5fsaB-3fdgA:undetectable | 5fsaB-3fdgA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgw | PUTATIVEPHOSPHOLIPASE B-LIKE2 (Mus musculus) |
PF04916(Phospholip_B) | 5 | GLY A 377GLN A 408LEU A 168GLY A 218PHE A 163 | None | 1.15A | 5fsaB-3fgwA:undetectable | 5fsaB-3fgwA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw6 | CELLULASE (unculturedbacterium) |
PF12891(Glyco_hydro_44) | 5 | GLY A 272GLN A 280LEU A 310GLY A 250PHE A 325 | None | 1.06A | 5fsaB-3fw6A:undetectable | 5fsaB-3fw6A:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hy8 | PYRIDOXINE-5'-PHOSPHATE OXIDASE (Homo sapiens) |
PF01243(Putative_PNPOx)PF10590(PNP_phzG_C) | 5 | GLY A 144GLN A 214LEU A 149TYR A 157PHE A 109 | NoneNoneNonePO4 A 360 (-3.7A)None | 1.24A | 5fsaB-3hy8A:undetectable | 5fsaB-3hy8A:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzd | IRON-CONTAININGALCOHOLDEHYDROGENASE (Cupriaviduspinatubonensis) |
PF00465(Fe-ADH) | 5 | GLY A 249LEU A 166GLY A 96THR A 100HIS A 71 | NoneNoneNoneNoneNAD A 400 (-3.4A) | 1.24A | 5fsaB-3jzdA:undetectable | 5fsaB-3jzdA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mda | DNA POLYMERASELAMBDA (Homo sapiens) |
PF10391(DNA_pol_lambd_f)PF14716(HHH_8)PF14791(DNA_pol_B_thumb)PF14792(DNA_pol_B_palm) | 5 | GLY A 508LEU A 532GLY A 524THR A 522PHE A 560 | None | 1.25A | 5fsaB-3mdaA:undetectable | 5fsaB-3mdaA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0h | GLUTATHIONEREDUCTASE (Bartonellahenselae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | TYR A 99GLY A 40PHE A 345ILE A 414GLY A 412 | None | 1.07A | 5fsaB-3o0hA:undetectable | 5fsaB-3o0hA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0r | NITRIC OXIDEREDUCTASE SUBUNIT B (Pseudomonasaeruginosa) |
PF00115(COX1) | 5 | GLY B 408GLN B 411PHE B 261ILE B 254GLY B 257 | None | 1.04A | 5fsaB-3o0rB:undetectable | 5fsaB-3o0rB:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9t | CHOLINEDEHYDROGENASE ANDRELATEDFLAVOPROTEINS (Aspergillusoryzae) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | GLY A 402LEU A 97GLY A 211THR A 203PHE A 512 | NoneFAY A 600 (-4.9A)NoneNoneFAY A 600 (-3.6A) | 1.25A | 5fsaB-3q9tA:undetectable | 5fsaB-3q9tA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjo | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF11838(ERAP1_C) | 5 | GLY A 676GLN A 675LEU A 686GLY A 920PHE A 699 | None | 0.94A | 5fsaB-3rjoA:undetectable | 5fsaB-3rjoA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 5 | GLY M 413GLN M 416LEU M 272ILE M 83GLY M 85 | None | 1.19A | 5fsaB-3rkoM:undetectable | 5fsaB-3rkoM:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tnl | SHIKIMATEDEHYDROGENASE (Listeriamonocytogenes) |
PF08501(Shikimate_dh_N) | 5 | GLY A 269GLN A 268LEU A 15PHE A 48PHE A 36 | NoneSKM A 293 (-3.3A)NoneNoneNone | 1.22A | 5fsaB-3tnlA:undetectable | 5fsaB-3tnlA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u1h | 3-ISOPROPYLMALATEDEHYDROGENASE (Bacillus sp.(in: Bacteria)) |
PF00180(Iso_dh) | 5 | GLY A 309TYR A 40GLY A 72THR A 296PHE A 36 | None | 0.95A | 5fsaB-3u1hA:undetectable | 5fsaB-3u1hA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsy | SORTILIN-RELATEDRECEPTOR (Homo sapiens) |
PF15901(Sortilin_C)PF15902(Sortilin-Vps10) | 5 | GLY A 238LEU A 231PHE A 284ILE A 293THR A 263 | None | 1.11A | 5fsaB-3wsyA:undetectable | 5fsaB-3wsyA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 5 | PHE A 380TYR A 197GLY A 249THR A 522PHE A 110 | None | 1.22A | 5fsaB-4ainA:undetectable | 5fsaB-4ainA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bob | ERPP PROTEIN (Borreliellaburgdorferi) |
PF02471(OspE) | 5 | LEU A 52PHE A 77ILE A 121GLY A 138THR A 150 | None | 1.18A | 5fsaB-4bobA:undetectable | 5fsaB-4bobA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ha4 | BETA-GALACTOSIDASE (Acidilobussaccharovorans) |
PF00232(Glyco_hydro_1) | 5 | GLY A 261ILE A 165GLY A 175THR A 181PHE A 291 | None | 1.28A | 5fsaB-4ha4A:undetectable | 5fsaB-4ha4A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j4b | PYLD (Methanosarcinabarkeri) |
no annotation | 5 | LEU A 101PHE A 63PHE A 108THR A 125PHE A 76 | None0TF A 904 (-3.8A)NoneNAI A 901 (-3.4A)None | 1.18A | 5fsaB-4j4bA:undetectable | 5fsaB-4j4bA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8p | FLAVODOXIN (Bacteroidesuniformis) |
PF12682(Flavodoxin_4) | 5 | GLY A 36PHE A 126TYR A 99PHE A 120PHE A 53 | GOL A 206 ( 3.3A)NoneGOL A 203 (-4.7A)NoneNone | 1.22A | 5fsaB-4j8pA:undetectable | 5fsaB-4j8pA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcs | ENOYL-COAHYDRATASE/ISOMERASE (Cupriavidusmetallidurans) |
PF00378(ECH_1) | 5 | GLY A 13LEU A 115PHE A 26ILE A 83GLY A 86 | None | 1.18A | 5fsaB-4jcsA:undetectable | 5fsaB-4jcsA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oua | PROTEOLYTICALLYACTIVATED FORM OFPPO4 TYROSINASE (Agaricusbisporus) |
PF00264(Tyrosinase) | 5 | GLY A 135LEU A 205ILE A 263GLY A 265THR A 268 | None | 1.27A | 5fsaB-4ouaA:0.4 | 5fsaB-4ouaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psw | HISTONEACETYLTRANSFERASETYPE B CATALYTICSUBUNITHISTONEACETYLTRANSFERASETYPE B SUBUNIT 2HISTONE H4 TYPE VIII (Ophiophagushannah;Saccharomycescerevisiae) |
PF00400(WD40)PF00583(Acetyltransf_1)PF10394(Hat1_N)PF12265(CAF1C_H4-bd)no annotation | 5 | TYR A 194GLY C 11LEU B 278PHE B 303GLY B 309 | None | 1.23A | 5fsaB-4pswA:undetectable | 5fsaB-4pswA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxn | UNCHARACTERIZEDPROTEIN (Zea mays) |
PF00171(Aldedh) | 5 | GLY A 270GLN A 423LEU A 343PHE A 352GLY A 370 | None | 1.25A | 5fsaB-4pxnA:undetectable | 5fsaB-4pxnA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tlv | ADP-RIBOSYLATINGTOXIN CARDS (Mycoplasmapneumoniae) |
PF02917(Pertussis_S1) | 5 | LEU A 403ILE A 280GLY A 279THR A 285PHE A 315 | None | 1.26A | 5fsaB-4tlvA:undetectable | 5fsaB-4tlvA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tpn | PUTATIVE P450-LIKEPROTEIN (Streptomycesscabiei) |
PF00067(p450) | 5 | GLY A 226LEU A 239TYR A 199GLY A 156THR A 215 | None | 1.28A | 5fsaB-4tpnA:26.6 | 5fsaB-4tpnA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uy6 | HISTIDINE-SPECIFICMETHYLTRANSFERASEEGTD (Mycolicibacteriumsmegmatis) |
PF10017(Methyltransf_33) | 5 | GLY A 25LEU A 167PHE A 159PHE A 142GLY A 86 | NoneNoneNoneSAH A 801 (-3.4A)SAH A 801 (-3.0A) | 1.01A | 5fsaB-4uy6A:undetectable | 5fsaB-4uy6A:21.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uym | 14-ALPHA STEROLDEMETHYLASE (Aspergillusfumigatus) |
PF00067(p450) | 5 | LEU A 125PHE A 130TYR A 136PHE A 229HIS A 374 | NoneVOR A 590 (-4.6A)HEM A 580 (-4.6A)NoneNone | 1.20A | 5fsaB-4uymA:51.5 | 5fsaB-4uymA:50.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uym | 14-ALPHA STEROLDEMETHYLASE (Aspergillusfumigatus) |
PF00067(p450) | 6 | TYR A 68GLY A 69LEU A 125PHE A 130TYR A 136HIS A 374 | NoneNoneNoneVOR A 590 (-4.6A)HEM A 580 (-4.6A)None | 1.01A | 5fsaB-4uymA:51.5 | 5fsaB-4uymA:50.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzs | ECU04_1440 PROTEINSIMILARITY TOHELICASE MOT1 (Encephalitozooncuniculi) |
PF00352(TBP)no annotation | 5 | GLY C 93GLN C 95LEU D 104PHE C 213ILE C 293 | None | 1.10A | 5fsaB-4wzsC:undetectable | 5fsaB-4wzsC:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8r | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Rhodobactersphaeroides) |
PF03480(DctP) | 5 | GLY A 192PHE A 131PHE A 93ILE A 137THR A 78 | None | 1.27A | 5fsaB-4x8rA:undetectable | 5fsaB-4x8rA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yxt | POLYKETIDEBIOSYNTHESIS3-HYDROXY-3-METHYLGLUTARYL-ACP SYNTHASEPKSG (Bacillussubtilis) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 5 | LEU A 302TYR A 115PHE A 303ILE A 78PHE A 334 | None | 1.04A | 5fsaB-4yxtA:undetectable | 5fsaB-4yxtA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | TYR A 875GLY A 876GLN A 485ILE A 395PHE A 737 | None | 1.24A | 5fsaB-5chcA:undetectable | 5fsaB-5chcA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfw | SINGLE CHAIN FVFRAGMENT (Mus musculus) |
PF07686(V-set) | 5 | TYR H 602GLN H 604ILE H 308THR H 124PHE H 753 | None | 1.29A | 5fsaB-5dfwH:undetectable | 5fsaB-5dfwH:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ee0 | OBG-LIKE ATPASE 1 (Oryza sativa) |
PF01926(MMR_HSR1)PF06071(YchF-GTPase_C) | 5 | GLY A 19LEU A 90PHE A 123THR A 258HIS A 303 | None | 1.25A | 5fsaB-5ee0A:undetectable | 5fsaB-5ee0A:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey7 | FRUCTOKINASE (Vibrio cholerae) |
PF00294(PfkB) | 5 | GLY A 307LEU A 80PHE A 63GLY A 65PHE A 75 | NA A 401 (-4.3A)NoneNoneNoneNone | 1.25A | 5fsaB-5ey7A:undetectable | 5fsaB-5ey7A:21.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 5 | TYR A 72GLY A 73GLY A 315THR A 318HIS A 381 | NoneNoneHEM A 601 (-3.5A)HEM A 601 (-3.4A)None | 0.86A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 9 | TYR A 72GLY A 73LEU A 129PHE A 134TYR A 140GLY A 314THR A 318HIS A 381PHE A 384 | NoneNoneNoneVOR A 602 (-4.7A)HEM A 601 (-4.3A)VOR A 602 (-3.0A)HEM A 601 (-3.4A)NoneNone | 0.62A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 6 | TYR A 72GLY A 73TYR A 140ILE A 471HIS A 381PHE A 384 | NoneNoneHEM A 601 (-4.3A)HEM A 601 ( 4.9A)NoneNone | 1.50A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 9 | TYR A 72LEU A 129PHE A 134TYR A 140PHE A 236GLY A 314THR A 318HIS A 381PHE A 384 | NoneNoneVOR A 602 (-4.7A)HEM A 601 (-4.3A)VOR A 602 (-4.4A)VOR A 602 (-3.0A)HEM A 601 (-3.4A)NoneNone | 0.64A | 5fsaB-5hs1A:54.7 | 5fsaB-5hs1A:59.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hst | POLYKETIDE SYNTHASETYPE I (Bacillusamyloliquefaciens) |
PF14765(PS-DH) | 5 | GLY A 222LEU A 284PHE A 213ILE A 59GLY A 56 | None | 1.18A | 5fsaB-5hstA:undetectable | 5fsaB-5hstA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huu | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE[UDP-FORMING] (Candidaalbicans) |
PF00982(Glyco_transf_20) | 5 | GLY A 406GLN A 409PHE A 463ILE A 139GLY A 167 | None | 1.10A | 5fsaB-5huuA:undetectable | 5fsaB-5huuA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvm | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Aspergillusfumigatus) |
PF00982(Glyco_transf_20) | 5 | GLY A 413GLN A 416PHE A 470ILE A 147GLY A 175 | None | 1.10A | 5fsaB-5hvmA:undetectable | 5fsaB-5hvmA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvo | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Aspergillusfumigatus) |
PF00982(Glyco_transf_20) | 5 | GLY A 413GLN A 416PHE A 470ILE A 146GLY A 175 | None | 1.16A | 5fsaB-5hvoA:undetectable | 5fsaB-5hvoA:22.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 5 | LEU A 130TYR A 127PHE A 237GLY A 315THR A 319 | None1YN A 602 ( 3.8A)1YN A 602 (-4.5A)1YN A 602 ( 3.6A)HEM A 601 ( 3.5A) | 1.26A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 5 | TYR A 73GLY A 74GLY A 316THR A 319HIS A 382 | 1YN A 602 (-4.9A)1YN A 602 ( 3.8A)HEM A 601 (-3.5A)HEM A 601 ( 3.5A)1YN A 602 (-4.2A) | 1.04A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 10 | TYR A 73GLY A 74LEU A 130PHE A 135TYR A 141PHE A 237GLY A 315THR A 319HIS A 382PHE A 385 | 1YN A 602 (-4.9A)1YN A 602 ( 3.8A)None1YN A 602 ( 4.6A)HEM A 601 (-4.2A)1YN A 602 (-4.5A)1YN A 602 ( 3.6A)HEM A 601 ( 3.5A)1YN A 602 (-4.2A)1YN A 602 (-4.8A) | 0.68A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 6 | TYR A 73GLY A 74TYR A 141ILE A 473HIS A 382PHE A 385 | 1YN A 602 (-4.9A)1YN A 602 ( 3.8A)HEM A 601 (-4.2A)HEM A 601 (-4.7A)1YN A 602 (-4.2A)1YN A 602 (-4.8A) | 1.39A | 5fsaB-5jlcA:52.0 | 5fsaB-5jlcA:62.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 5 | TYR B 247PHE B 106PHE B 76ILE B 461GLY B 227 | None | 1.29A | 5fsaB-5kohB:undetectable | 5fsaB-5kohB:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kov | PL-2 SCFV CHAIN (Mus musculus) |
PF07686(V-set) | 5 | GLY C1057PHE C 27ILE C 51GLY C 33HIS C1055 | None | 1.20A | 5fsaB-5kovC:undetectable | 5fsaB-5kovC:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ktz | VHH 12B (Camelusdromedarius) |
PF07686(V-set) | 5 | GLY 7 15GLN 7 13LEU 7 20GLY 7 115PHE 7 68 | None | 1.24A | 5fsaB-5ktz7:undetectable | 5fsaB-5ktz7:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgz | 8-DEMETHYLNOVOBIOCICACIDC(8)-METHYLTRANSFERASE (Streptomycesniveus) |
PF13649(Methyltransf_25) | 5 | GLY A 34LEU A 66PHE A 92GLY A 51PHE A 61 | None | 1.02A | 5fsaB-5mgzA:undetectable | 5fsaB-5mgzA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ols | RHAMNOGALACTURONANLYASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | GLY A 57LEU A 47TYR A 67PHE A 129ILE A 144 | None | 1.07A | 5fsaB-5olsA:undetectable | 5fsaB-5olsA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5osn | CAPSID PROTEIN (Enterovirus E) |
PF00073(Rhv) | 5 | LEU B 166PHE C 218ILE C 215THR B 119PHE B 156 | None | 1.24A | 5fsaB-5osnB:undetectable | 5fsaB-5osnB:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3f | TUBULIN ALPHA-1CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | GLY A 135GLN A 134LEU A 379ILE A 292PHE A 170 | None | 1.19A | 5fsaB-5w3fA:undetectable | 5fsaB-5w3fA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y4k | DMSP LYASE DDDY (Acinetobacterbereziniae) |
no annotation | 5 | GLY A 345GLN A 348PHE A 332ILE A 270THR A 357 | None | 1.14A | 5fsaB-5y4kA:undetectable | 5fsaB-5y4kA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zb3 | - (-) |
no annotation | 5 | TYR A 452LEU A 376PHE A 335PHE A 326THR A 436 | None | 1.08A | 5fsaB-5zb3A:undetectable | 5fsaB-5zb3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bf2 | ISOAMYLASE (Pseudomonasamyloderamosa) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 3 | PRO A 499LEU A 643SER A 635 | None | 0.80A | 5fsaB-1bf2A:0.0 | 5fsaB-1bf2A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fsk | ANTIBODY HEAVY CHAINFAB (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | PRO C 86LEU C 11SER C 17 | None | 0.55A | 5fsaB-1fskC:0.0 | 5fsaB-1fskC:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iu1 | GAMMA1-ADAPTIN (Homo sapiens) |
PF02883(Alpha_adaptinC2) | 3 | PRO A 765LEU A 798SER A 768 | None | 0.78A | 5fsaB-1iu1A:undetectable | 5fsaB-1iu1A:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iyb | RIBONUCLEASE (Nicotianaglutinosa) |
PF00445(Ribonuclease_T2) | 3 | PRO A 14LEU A 123SER A 34 | None | 0.62A | 5fsaB-1iybA:0.0 | 5fsaB-1iybA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iyb | RIBONUCLEASE (Nicotianaglutinosa) |
PF00445(Ribonuclease_T2) | 3 | PRO A 14LEU A 127SER A 34 | None | 0.77A | 5fsaB-1iybA:0.0 | 5fsaB-1iybA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jeq | KU70 (Homo sapiens) |
PF02037(SAP)PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 3 | PRO A 370LEU A 413SER A 383 | None | 0.72A | 5fsaB-1jeqA:0.0 | 5fsaB-1jeqA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jy5 | CALSEPRRP (Calystegiasepium) |
PF00445(Ribonuclease_T2) | 3 | PRO A 199LEU A 204SER A 172 | None | 0.72A | 5fsaB-1jy5A:0.0 | 5fsaB-1jy5A:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lzk | HEROIN ESTERASE (Rhodococcus sp.) |
PF07859(Abhydrolase_3) | 3 | PRO A 180LEU A 83SER A 152 | None | 0.84A | 5fsaB-1lzkA:0.0 | 5fsaB-1lzkA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mh6 | BLEOMYCIN RESISTANCEPROTEIN (Klebsiellapneumoniae) |
no annotation | 3 | PRO A 309LEU A 245SER A 216 | None | 0.73A | 5fsaB-1mh6A:undetectable | 5fsaB-1mh6A:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n9b | BETA-LACTAMASE SHV-2 (Klebsiellapneumoniae) |
PF13354(Beta-lactamase2) | 3 | PRO A 107LEU A 122SER A 130 | NoneNoneEPE A 400 (-2.5A) | 0.78A | 5fsaB-1n9bA:0.0 | 5fsaB-1n9bA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ocm | MALONAMIDASE E2 (Bradyrhizobiumjaponicum) |
PF01425(Amidase) | 3 | PRO A 115LEU A 119SER A 355 | None | 0.84A | 5fsaB-1ocmA:undetectable | 5fsaB-1ocmA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1on9 | METHYLMALONYL-COACARBOXYLTRANSFERASE12S SUBUNIT (Propionibacteriumfreudenreichii) |
PF01039(Carboxyl_trans) | 3 | PRO A 372LEU A 317SER A 340 | None | 0.58A | 5fsaB-1on9A:undetectable | 5fsaB-1on9A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q47 | SEMAPHORIN 3A (Mus musculus) |
PF01403(Sema) | 3 | PRO A 415LEU A 308SER A 294 | None | 0.67A | 5fsaB-1q47A:undetectable | 5fsaB-1q47A:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6p | PHENYLALANINEAMMONIA-LYASE (Rhodotorulatoruloides) |
PF00221(Lyase_aromatic) | 3 | PRO A 369LEU A 335SER A 310 | None | 0.82A | 5fsaB-1t6pA:1.5 | 5fsaB-1t6pA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vqv | THIAMINEMONOPHOSPHATE KINASE (Aquifexaeolicus) |
PF00586(AIRS) | 3 | PRO A 57LEU A 86SER A 95 | None | 0.75A | 5fsaB-1vqvA:undetectable | 5fsaB-1vqvA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1we5 | PUTATIVE FAMILY 31GLUCOSIDASE YICI (Escherichiacoli) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 3 | PRO A 678LEU A 340SER A 268 | None | 0.73A | 5fsaB-1we5A:undetectable | 5fsaB-1we5A:21.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1x8v | CYTOCHROME P450 51 (Mycobacteriumtuberculosis) |
PF00067(p450) | 3 | PRO A 178LEU A 29SER A 431 | None | 0.77A | 5fsaB-1x8vA:34.6 | 5fsaB-1x8vA:30.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aey | FRUCTAN1-EXOHYDROLASE IIA (Cichoriumintybus) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 3 | PRO A 253LEU A 266SER A 258 | None | 0.57A | 5fsaB-2aeyA:undetectable | 5fsaB-2aeyA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5y | YKUV PROTEIN (Bacillussubtilis) |
PF00578(AhpC-TSA) | 3 | PRO A 70LEU A 17SER A 98 | None | 0.80A | 5fsaB-2b5yA:undetectable | 5fsaB-2b5yA:14.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dhz | RAP GUANINENUCLEOTIDE EXCHANGEFACTOR (GEF)-LIKE 1 (Homo sapiens) |
no annotation | 3 | PRO A 17LEU A 58SER A 94 | None | 0.82A | 5fsaB-2dhzA:undetectable | 5fsaB-2dhzA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2djk | PROTEINDISULFIDE-ISOMERASE (Humicolainsolens) |
PF13848(Thioredoxin_6) | 3 | PRO A 120LEU A 72SER A 124 | None | 0.85A | 5fsaB-2djkA:undetectable | 5fsaB-2djkA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9x | DNA REPLICATIONCOMPLEX GINS PROTEINPSF2 (Homo sapiens) |
PF05916(Sld5) | 3 | PRO B 19LEU B 33SER B 22 | None | 0.79A | 5fsaB-2e9xB:undetectable | 5fsaB-2e9xB:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fge | ZINC METALLOPROTEASE(INSULINASE FAMILY) (Arabidopsisthaliana) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF08367(M16C_assoc) | 3 | PRO A 287LEU A 189SER A 183 | None | 0.82A | 5fsaB-2fgeA:undetectable | 5fsaB-2fgeA:19.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk0 | D-PSICOSE3-EPIMERASE (Agrobacteriumtumefaciens) |
PF01261(AP_endonuc_2) | 3 | PRO A 68LEU A 147SER A 110 | PRO A 68 ( 1.1A)LEU A 147 ( 0.6A)SER A 110 ( 0.0A) | 0.65A | 5fsaB-2hk0A:undetectable | 5fsaB-2hk0A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l3u | YBBR FAMILY PROTEIN (Desulfitobacteriumhafniense) |
no annotation | 3 | PRO A 78LEU A 24SER A 28 | None | 0.76A | 5fsaB-2l3uA:undetectable | 5fsaB-2l3uA:12.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ood | BLR3880 PROTEIN (Bradyrhizobiumdiazoefficiens) |
PF01979(Amidohydro_1) | 3 | PRO A 374LEU A 409SER A 439 | None | 0.76A | 5fsaB-2oodA:undetectable | 5fsaB-2oodA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oq3 | MANNITOL-SPECIFICCRYPTICPHOSPHOTRANSFERASEENZYME IIA COMPONENT (Escherichiacoli) |
PF00359(PTS_EIIA_2) | 3 | PRO A 8LEU A 103SER A 31 | None | 0.81A | 5fsaB-2oq3A:undetectable | 5fsaB-2oq3A:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qnk | 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE (Homo sapiens) |
PF06052(3-HAO) | 3 | PRO A 86LEU A 172SER A 176 | None | 0.76A | 5fsaB-2qnkA:undetectable | 5fsaB-2qnkA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vak | SIGMA A (Avianorthoreovirus) |
PF03084(Sigma_1_2) | 3 | PRO A 86LEU A 80SER A 20 | None | 0.68A | 5fsaB-2vakA:undetectable | 5fsaB-2vakA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xij | METHYLMALONYL-COAMUTASE,MITOCHONDRIAL (Homo sapiens) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 3 | PRO A 339LEU A 305SER A 342 | None | 0.84A | 5fsaB-2xijA:undetectable | 5fsaB-2xijA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yv5 | YJEQ PROTEIN (Aquifexaeolicus) |
PF03193(RsgA_GTPase) | 3 | PRO A 92LEU A 99SER A 174 | NoneNoneGDP A1001 ( 4.1A) | 0.85A | 5fsaB-2yv5A:undetectable | 5fsaB-2yv5A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ak5 | HEMOGLOBIN-BINDINGPROTEASE HBP (Escherichiacoli) |
PF02395(Peptidase_S6) | 3 | PRO A 661LEU A 752SER A 689 | None | 0.74A | 5fsaB-3ak5A:undetectable | 5fsaB-3ak5A:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ay5 | CYCLIN-D1-BINDINGPROTEIN 1 (Homo sapiens) |
PF13324(GCIP) | 3 | PRO A 17LEU A 77SER A 81 | None | 0.69A | 5fsaB-3ay5A:undetectable | 5fsaB-3ay5A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3btp | SINGLE-STRANDDNA-BINDING PROTEIN (Agrobacteriumfabrum) |
PF07229(VirE2) | 3 | PRO A 161LEU A 264SER A 258 | None | 0.78A | 5fsaB-3btpA:undetectable | 5fsaB-3btpA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3l | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Homo sapiens) |
PF00305(Lipoxygenase) | 3 | PRO A 558LEU A 296SER A 345 | None | 0.60A | 5fsaB-3d3lA:1.9 | 5fsaB-3d3lA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eay | SENTRIN-SPECIFICPROTEASE 7 (Homo sapiens) |
PF02902(Peptidase_C48) | 3 | PRO A 788LEU A 722SER A 739 | None | 0.82A | 5fsaB-3eayA:undetectable | 5fsaB-3eayA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fle | SE_1780 PROTEIN (Staphylococcusepidermidis) |
PF06028(DUF915) | 3 | PRO A 164LEU A 94SER A 127 | None | 0.82A | 5fsaB-3fleA:undetectable | 5fsaB-3fleA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fm0 | PROTEIN CIAO1 (Homo sapiens) |
PF00400(WD40) | 3 | PRO A 160LEU A 263SER A 205 | None | 0.78A | 5fsaB-3fm0A:undetectable | 5fsaB-3fm0A:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjb | GLUCOSE-6-PHOSPHATEISOMERASE (Vibrio cholerae) |
PF00342(PGI) | 3 | PRO A 407LEU A 170SER A 410 | None | 0.80A | 5fsaB-3hjbA:undetectable | 5fsaB-3hjbA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 3 (Thermusthermophilus) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 3 | PRO 3 551LEU 3 345SER 3 557 | None | 0.74A | 5fsaB-3i9v3:undetectable | 5fsaB-3i9v3:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1j | ATP-DEPENDENTPROTEASE LON (Thermococcusonnurineus) |
PF01078(Mg_chelatase)PF05362(Lon_C)PF13654(AAA_32) | 3 | PRO A 581LEU A 446SER A 550 | None | 0.68A | 5fsaB-3k1jA:undetectable | 5fsaB-3k1jA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwb | PREPHENATEDEHYDRATASE (Paenarthrobacteraurescens) |
PF00800(PDT)PF01842(ACT) | 3 | PRO A 191LEU A 183SER A 276 | None | 0.82A | 5fsaB-3mwbA:undetectable | 5fsaB-3mwbA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myr | NICKEL-DEPENDENTHYDROGENASE LARGESUBUNIT (Allochromatiumvinosum) |
PF00374(NiFeSe_Hases) | 3 | PRO B1225LEU B1228SER B1232 | None | 0.81A | 5fsaB-3myrB:1.0 | 5fsaB-3myrB:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ol2 | SEMAPHORIN-4D (Homo sapiens) |
PF00047(ig)PF01403(Sema)PF01437(PSI) | 3 | PRO A 406LEU A 293SER A 282 | None | 0.76A | 5fsaB-3ol2A:undetectable | 5fsaB-3ol2A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pb9 | GLUTAMINYL-PEPTIDECYCLOTRANSFERASE-LIKE PROTEIN (Homo sapiens) |
PF04389(Peptidase_M28) | 3 | PRO X 320LEU X 339SER X 323 | None | 0.61A | 5fsaB-3pb9X:undetectable | 5fsaB-3pb9X:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w0l | GLUCOKINASEREGULATORY PROTEIN (Xenopus laevis) |
no annotation | 3 | PRO B 453LEU B 406SER B 430 | None | 0.81A | 5fsaB-3w0lB:0.4 | 5fsaB-3w0lB:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3whe | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 3 | PRO A 215LEU A 194SER A 199 | None | 0.74A | 5fsaB-3wheA:undetectable | 5fsaB-3wheA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ag4 | MONOCLONAL ANTIBODY3E3 HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | PRO H 82LEU H 11SER H 17 | None | 0.75A | 5fsaB-4ag4H:undetectable | 5fsaB-4ag4H:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b5q | GLYCOSIDE HYDROLASEFAMILY 61 PROTEIN D (Phanerochaetechrysosporium) |
PF03443(Glyco_hydro_61) | 3 | PRO A 10LEU A 141SER A 61 | None | 0.81A | 5fsaB-4b5qA:undetectable | 5fsaB-4b5qA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4blf | SINGLE-STRANDDNA-BINDING PROTEIN (Agrobacteriumtumefaciens) |
PF07229(VirE2) | 3 | PRO A 161LEU A 264SER A 258 | None | 0.79A | 5fsaB-4blfA:undetectable | 5fsaB-4blfA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cak | INTEGRIN BETA-3 (Homo sapiens) |
PF00362(Integrin_beta)PF07965(Integrin_B_tail)PF07974(EGF_2)PF17205(PSI_integrin) | 3 | PRO B 363LEU B 92SER B 413 | None | 0.76A | 5fsaB-4cakB:undetectable | 5fsaB-4cakB:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fhn | NUCLEOPORIN NUP120 (Schizosaccharomycespombe) |
PF11715(Nup160) | 3 | PRO B 96LEU B 673SER B 92 | None | 0.79A | 5fsaB-4fhnB:undetectable | 5fsaB-4fhnB:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gbr | BETA-2 ADRENERGICRECEPTOR (Homo sapiens) |
PF00001(7tm_1) | 3 | PRO A 211LEU A 259SER A 207 | NoneNoneCAU A 500 (-4.1A) | 0.82A | 5fsaB-4gbrA:0.0 | 5fsaB-4gbrA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gq1 | NUP37 (Schizosaccharomycespombe) |
PF00400(WD40) | 3 | PRO A 195LEU A 283SER A 264 | None | 0.83A | 5fsaB-4gq1A:undetectable | 5fsaB-4gq1A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gz8 | SEMAPHORIN-3A (Mus musculus) |
PF01403(Sema) | 3 | PRO A 415LEU A 308SER A 294 | None | 0.70A | 5fsaB-4gz8A:undetectable | 5fsaB-4gz8A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hmw | PYRIDOXAMINE5'-PHOSPHATE OXIDASE (Burkholderialata) |
PF01243(Putative_PNPOx)PF10590(PNP_phzG_C) | 3 | PRO A 169LEU A 162SER A 137 | None | 0.68A | 5fsaB-4hmwA:undetectable | 5fsaB-4hmwA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kys | THIAMINEPYRIDINYLASE I (Clostridiumbotulinum) |
PF01547(SBP_bac_1) | 3 | PRO A 246LEU A 186SER A 251 | None | 0.54A | 5fsaB-4kysA:undetectable | 5fsaB-4kysA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l15 | FIDGETIN-LIKEPROTEIN 1 (Caenorhabditiselegans) |
PF00004(AAA)PF09336(Vps4_C) | 3 | PRO A 357LEU A 321SER A 519 | None | 0.70A | 5fsaB-4l15A:undetectable | 5fsaB-4l15A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ld7 | DIMETHYLALLYLTRYPTOPHAN SYNTHASE (Aspergillusfischeri) |
PF11991(Trp_DMAT) | 3 | PRO A 243LEU A 281SER A 346 | None | 0.72A | 5fsaB-4ld7A:undetectable | 5fsaB-4ld7A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lg9 | F-BOX-LIKE/WDREPEAT-CONTAININGPROTEIN TBL1XR1 (Homo sapiens) |
PF00400(WD40) | 3 | PRO A 179LEU A 231SER A 235 | None | 0.77A | 5fsaB-4lg9A:undetectable | 5fsaB-4lg9A:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n2r | ALPHA-L-ARABINOFURANOSIDASE UMABF62A (Ustilago maydis) |
PF03664(Glyco_hydro_62) | 3 | PRO A 41LEU A 283SER A 267 | None | 0.81A | 5fsaB-4n2rA:undetectable | 5fsaB-4n2rA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5o | QUINONPROTEINALCOHOLDEHYDROGENASE-LIKEPROTEIN (Bacteroidesthetaiotaomicron) |
PF16819(DUF5074)PF16820(PKD_3) | 3 | PRO A 348LEU A 398SER A 442 | None | 0.71A | 5fsaB-4r5oA:undetectable | 5fsaB-4r5oA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ufc | GH95 (Bacteroidesovatus) |
PF14498(Glyco_hyd_65N_2) | 3 | PRO A 188LEU A 59SER A 360 | None | 0.72A | 5fsaB-4ufcA:undetectable | 5fsaB-4ufcA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w6z | ALCOHOLDEHYDROGENASE 1 (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | PRO A 271LEU A 182SER A 248 | None8ID A 403 (-3.3A)8ID A 403 (-3.5A) | 0.78A | 5fsaB-4w6zA:undetectable | 5fsaB-4w6zA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj3 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A (Pseudomonasaeruginosa) |
PF01425(Amidase) | 3 | PRO A 180LEU A 120SER A 176 | None | 0.83A | 5fsaB-4wj3A:1.1 | 5fsaB-4wj3A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xk1 | PHOSPHOSERINEAMINOTRANSFERASE (Pseudomonasaeruginosa) |
PF00266(Aminotran_5) | 3 | PRO A 132LEU A 139SER A 122 | None | 0.74A | 5fsaB-4xk1A:undetectable | 5fsaB-4xk1A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yra | L-THREONINE3-DEHYDROGENASE,MITOCHONDRIAL (Mus musculus) |
PF01370(Epimerase) | 3 | PRO A 223LEU A 355SER A 294 | None | 0.82A | 5fsaB-4yraA:undetectable | 5fsaB-4yraA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zyl | RPHYB PROTEIN (Rhodopseudomonaspalustris) |
PF00072(Response_reg) | 3 | PRO A 8LEU A 136SER A 33 | None | 0.78A | 5fsaB-4zylA:undetectable | 5fsaB-4zylA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a20 | MAJOR TAIL PROTEINGP17.1 (Bacillus phageSPP1) |
PF06199(Phage_tail_2) | 3 | PRO H 147LEU H 43SER H 58 | None | 0.44A | 5fsaB-5a20H:undetectable | 5fsaB-5a20H:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3f | DYNAMIN 3 (Homo sapiens) |
PF00169(PH)PF00350(Dynamin_N)PF01031(Dynamin_M)PF02212(GED) | 3 | PRO A 68LEU A 29SER A 117 | None | 0.77A | 5fsaB-5a3fA:0.1 | 5fsaB-5a3fA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqp | EDTA MONOOXYGENASE (EDTA-degradingbacterium BNC1) |
PF00296(Bac_luciferase) | 3 | PRO A 59LEU A 55SER A 96 | None | 0.83A | 5fsaB-5dqpA:undetectable | 5fsaB-5dqpA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | PRO B 135LEU B 64SER B 58 | None | 0.84A | 5fsaB-5fq6B:undetectable | 5fsaB-5fq6B:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gj8 | ACYL-COADEHYDROGENASE TYPE 2DOMAIN PROTEIN (Alicyclobacillusacidocaldarius) |
PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 3 | PRO A 42LEU A 24SER A 86 | None | 0.61A | 5fsaB-5gj8A:undetectable | 5fsaB-5gj8A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gj8 | ACYL-COADEHYDROGENASE TYPE 2DOMAIN PROTEIN (Alicyclobacillusacidocaldarius) |
PF02771(Acyl-CoA_dh_N) | 3 | PRO D 42LEU D 24SER D 86 | None | 0.54A | 5fsaB-5gj8D:undetectable | 5fsaB-5gj8D:13.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7j | ELONGATION FACTOR 2 (Pyrococcushorikoshii) |
no annotation | 3 | PRO A 130LEU A 692SER A 688 | None | 0.80A | 5fsaB-5h7jA:undetectable | 5fsaB-5h7jA:10.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjr | NEUTRALALPHA-GLUCOSIDASE AB (Mus musculus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 3 | PRO A 693LEU A 622SER A 664 | None | 0.65A | 5fsaB-5hjrA:undetectable | 5fsaB-5hjrA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iz5 | CYTOSOLICPHOSPHOLIPASE A2DELTA (Homo sapiens) |
no annotation | 3 | PRO B 45LEU B 134SER B 68 | None | 0.61A | 5fsaB-5iz5B:undetectable | 5fsaB-5iz5B:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jp3 | XANTHOMONAS OUTERPROTEIN D (Xanthomonaseuvesicatoria) |
PF02902(Peptidase_C48) | 3 | PRO A 503LEU A 412SER A 469 | None | 0.76A | 5fsaB-5jp3A:undetectable | 5fsaB-5jp3A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ljo | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMC (Escherichiacoli) |
PF06804(Lipoprotein_18) | 3 | PRO C 88LEU C 178SER C 105 | None | 0.57A | 5fsaB-5ljoC:undetectable | 5fsaB-5ljoC:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m59 | PRE-MRNA SPLICINGHELICASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 3 | PRO A 552LEU A 933SER A 727 | None | 0.63A | 5fsaB-5m59A:undetectable | 5fsaB-5m59A:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oat | SERINE/THREONINE-PROTEIN KINASE PINK1,MITOCHONDRIAL-LIKEPROTEIN (Triboliumcastaneum) |
no annotation | 3 | PRO A 473LEU A 338SER A 407 | None | 0.75A | 5fsaB-5oatA:undetectable | 5fsaB-5oatA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tih | CYRPA ANTIBODY FABHEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | PRO H 86LEU H 11SER H 17 | None | 0.72A | 5fsaB-5tihH:undetectable | 5fsaB-5tihH:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u22 | N2152 (Neocallimastixfrontalis) |
PF01229(Glyco_hydro_39) | 3 | PRO A 69LEU A 300SER A 65 | None | 0.84A | 5fsaB-5u22A:undetectable | 5fsaB-5u22A:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ubj | ALPHA-L-ARABINOFURANOSIDASE AXHA-2 (Aspergillusnidulans) |
PF03664(Glyco_hydro_62) | 3 | PRO A 55LEU A 300SER A 284 | None | 0.77A | 5fsaB-5ubjA:undetectable | 5fsaB-5ubjA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhk | O-GLCNACASETIM-BARREL DOMAIN (Homo sapiens) |
PF07555(NAGidase) | 3 | PRO A 209LEU A 171SER A 168 | None | 0.85A | 5fsaB-5uhkA:undetectable | 5fsaB-5uhkA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uz5 | U1 SMALL NUCLEARRIBONUCLEOPROTEIN CU1 SMALL NUCLEARRIBONUCLEOPROTEINCOMPONENT PRP42 (Saccharomycescerevisiae) |
no annotation | 3 | PRO B 113LEU D 64SER D 266 | None | 0.69A | 5fsaB-5uz5B:undetectable | 5fsaB-5uz5B:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5via | PSEUDOPEROXIDASE (Leishmaniamajor) |
PF00141(peroxidase) | 3 | PRO A 59LEU A 332SER A 336 | None | 0.76A | 5fsaB-5viaA:undetectable | 5fsaB-5viaA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wtf | VP1 (Hepatovirus A) |
PF12944(HAV_VP) | 3 | PRO A 119LEU A 264SER A 271 | None | 0.62A | 5fsaB-5wtfA:undetectable | 5fsaB-5wtfA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xde | THERMOPHILICDIBENZOTHIOPHENEDESULFURIZATIONENZYME C (Paenibacillussp. A11-2) |
PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 3 | PRO A 42LEU A 24SER A 86 | None | 0.62A | 5fsaB-5xdeA:undetectable | 5fsaB-5xdeA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xpg | UNCHARACTERIZEDPROTEIN (Thermusthermophilus) |
no annotation | 3 | PRO A 330LEU A 455SER A 645 | None | 0.83A | 5fsaB-5xpgA:undetectable | 5fsaB-5xpgA:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | DNA-DEPENDENTPROTEIN KINASECATALYTIC SUBUNIT (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08163(NUC194) | 3 | PRO C 897LEU C2563SER C2789 | None | 0.83A | 5fsaB-5y3rC:undetectable | 5fsaB-5y3rC:8.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yly | NITRATE REDUCTASE (Ulva prolifera) |
no annotation | 3 | PRO A 721LEU A 756SER A 760 | None | 0.80A | 5fsaB-5ylyA:undetectable | 5fsaB-5ylyA:11.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c08 | SODIUM-COUPLEDNEUTRAL AMINO ACIDTRANSPORTER 9 (Danio rerio) |
no annotation | 3 | PRO C 415LEU C 350SER C 492 | None | 0.71A | 5fsaB-6c08C:undetectable | 5fsaB-6c08C:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c66 | CRISPR-ASSOCIATEDPROTEIN, CSE1 FAMILY (Thermobifidafusca) |
no annotation | 3 | PRO A 307LEU A 260SER A 264 | None | 0.72A | 5fsaB-6c66A:undetectable | 5fsaB-6c66A:9.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6caa | ELECTROGENIC SODIUMBICARBONATECOTRANSPORTER 1 (Homo sapiens) |
no annotation | 3 | PRO A 795LEU A 482SER A 460 | None | 0.77A | 5fsaB-6caaA:undetectable | 5fsaB-6caaA:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cv0 | SPIKE GLYCOPROTEIN (Aviancoronavirus) |
no annotation | 3 | PRO A 770LEU A 681SER A 671 | None | 0.59A | 5fsaB-6cv0A:undetectable | 5fsaB-6cv0A:9.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cvq | APRATAXIN (Homo sapiens) |
no annotation | 3 | PRO A 206LEU A 213SER A 209 | None | 0.83A | 5fsaB-6cvqA:undetectable | 5fsaB-6cvqA:11.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cvq | APRATAXIN (Homo sapiens) |
no annotation | 3 | PRO A 254LEU A 203SER A 212 | AMP A 401 (-4.5A)AMP A 401 ( 4.7A)None | 0.84A | 5fsaB-6cvqA:undetectable | 5fsaB-6cvqA:11.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE SUBUNITALPHA, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 3 | PRO C 159LEU C 383SER C 369 | None | 0.84A | 5fsaB-6fkhC:undetectable | 5fsaB-6fkhC:10.99 |