SIMILAR PATTERNS OF AMINO ACIDS FOR 5FLC_C_RAPC999

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eco ERYTHROCRUORIN
(CARBONMONOXY)

(Chironomus
thummi) 		PF00042
(Globin) 		4 PHE A  65
GLY A  64
THR A  82
PHE A 129
 HEM  A 137 (-4.9A)
None
None
None
 0.98A 5flcB-1ecoA:
undetectable		 5flcB-1ecoA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0v PROTEINASE A

(Saccharomyces
cerevisiae) 		PF00026
(Asp) 		4 GLU A 207
PHE A 194
GLY A 210
TYR A 203
 None
None
None
NAG  A 501 ( 3.8A)
 0.95A 5flcB-1g0vA:
undetectable		 5flcB-1g0vA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ize ASPARTIC PROTEINASE

(Aspergillus
oryzae) 		PF00026
(Asp) 		4 PHE A 298
GLY A 299
THR A 194
TYR A 198
 None
 0.96A 5flcB-1izeA:
undetectable		 5flcB-1izeA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4v CYSTEINE
ENDOPEPTIDASE

(Ricinus
communis) 		PF00112
(Peptidase_C1) 		4 GLU A  51
SER A  25
GLY A  68
TYR A  94
 None
 0.93A 5flcB-1s4vA:
0.0		 5flcB-1s4vA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua4 ADP-DEPENDENT
GLUCOKINASE

(Pyrococcus
furiosus) 		PF04587
(ADP_PFK_GK) 		4 GLU A 266
SER A 232
GLY A  28
THR A 208
 None
 0.99A 5flcB-1ua4A:
0.0		 5flcB-1ua4A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uch UBIQUITIN C-TERMINAL
HYDROLASE UCH-L3

(Homo sapiens) 		PF01088
(Peptidase_C12) 		4 GLU A 182
PHE A 170
GLY A  99
PHE A 212
 None
 0.97A 5flcB-1uchA:
0.0		 5flcB-1uchA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wve 4-CRESOL
DEHYDROGENASE
[HYDROXYLATING]
FLAVOPROTEIN SUBUNIT

(Pseudomonas
putida) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 SER A 156
PHE A 134
GLY A 135
THR A 165
 None
 0.99A 5flcB-1wveA:
1.8		 5flcB-1wveA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x4g NUCLEOLYSIN TIAR

(Homo sapiens) 		PF00076
(RRM_1) 		4 GLU A  72
PHE A  49
GLY A  50
PHE A  14
 None
 0.95A 5flcB-1x4gA:
0.0		 5flcB-1x4gA:
6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybi NON-TOXIN
HAEMAGGLUTININ HA34

(Clostridium
botulinum) 		PF05588
(Botulinum_HA-17)
PF14200
(RicinB_lectin_2) 		4 SER A  63
THR A  17
TRP A  48
TYR A  29
 None
 0.93A 5flcB-1ybiA:
undetectable		 5flcB-1ybiA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl6 BOTULINUM NEUROTOXIN
TYPE E

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 GLU A 188
SER A 186
GLY A 151
TYR A  67
 None
 0.99A 5flcB-1zl6A:
0.0		 5flcB-1zl6A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLU A 334
GLY A  15
THR A  10
PHE A 308
 None
FAD  A4750 (-3.7A)
None
None
 0.92A 5flcB-1zy8A:
undetectable		 5flcB-1zy8A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7b CARBOXYLESTERASE

(uncultured
archaeon) 		PF07859
(Abhydrolase_3) 		4 GLU A 256
SER A 194
PHE A 198
GLY A 199
 None
 0.81A 5flcB-2c7bA:
undetectable		 5flcB-2c7bA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyn ALPHA-ACTININ 1

(Homo sapiens) 		PF00307
(CH) 		4 PHE A  59
GLY A  62
THR A  38
PHE A 134
 None
 0.98A 5flcB-2eynA:
undetectable		 5flcB-2eynA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqz R.ECL18KI

(Enterobacter
cloacae) 		PF09019
(EcoRII-C) 		4 GLU A 129
PHE A 124
GLY A 121
THR A 230
 None
 0.93A 5flcB-2fqzA:
undetectable		 5flcB-2fqzA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gee HYPOTHETICAL PROTEIN

(Homo sapiens) 		PF00041
(fn3) 		4 SER A 101
PHE A 102
GLY A 111
THR A 178
 None
 0.90A 5flcB-2geeA:
undetectable		 5flcB-2geeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2npu FKBP12-RAPAMYCIN
COMPLEX-ASSOCIATED
PROTEIN

(Homo sapiens) 		PF08771
(FRB_dom) 		4 GLU A2032
GLY A2040
THR A2098
TRP A2101
 None
 0.94A 5flcB-2npuA:
13.9		 5flcB-2npuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2npu FKBP12-RAPAMYCIN
COMPLEX-ASSOCIATED
PROTEIN

(Homo sapiens) 		PF08771
(FRB_dom) 		4 GLU A2032
SER A2035
GLY A2040
TRP A2101
 None
 0.96A 5flcB-2npuA:
13.9		 5flcB-2npuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqk NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		4 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
 0.92A 5flcB-2qqkA:
undetectable		 5flcB-2qqkA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqo NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		4 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
None
None
TRS  A 602 ( 3.6A)
 0.94A 5flcB-2qqoA:
undetectable		 5flcB-2qqoA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ylk CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00942
(CBM_3) 		4 GLU A  95
THR A 130
TYR A   6
PHE A 123
 None
 0.92A 5flcB-2ylkA:
undetectable		 5flcB-2ylkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT

(Methanocaldococcus
jannaschii) 		PF01174
(SNO) 		4 GLU A  93
GLY A  52
THR A  74
TYR A 159
 None
 0.99A 5flcB-2ywjA:
undetectable		 5flcB-2ywjA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 GLU A 348
GLY A  93
THR A  97
TYR A  45
 None
SO4  A2003 ( 4.0A)
None
None
 0.86A 5flcB-2zb4A:
undetectable		 5flcB-2zb4A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a58 GTP-BINDING PROTEIN
RHO1

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		4 GLU B 163
GLY B 169
THR B  24
PHE B  89
 None
None
MG  B 401 ( 2.8A)
None
 0.91A 5flcB-3a58B:
undetectable		 5flcB-3a58B:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axi OLIGO-1,6-GLUCOSIDAS
E IMA1

(Saccharomyces
cerevisiae) 		PF00128
(Alpha-amylase) 		4 SER A 162
GLY A 160
TYR A 174
PHE A 173
 None
 0.99A 5flcB-3axiA:
undetectable		 5flcB-3axiA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxw CHITINASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		no annotation 4 SER B 242
GLY B 212
THR B 238
PHE B 334
 None
 0.86A 5flcB-3bxwB:
undetectable		 5flcB-3bxwB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		4 PHE A 257
GLY A 258
THR A 236
PHE A 202
 None
 0.96A 5flcB-3cskA:
2.7		 5flcB-3cskA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkn PREPROTEIN
TRANSLOCASE SUBUNIT
SECY

(Canis lupus) 		PF00344
(SecY) 		4 GLU A 208
SER A 307
GLY A 215
THR A 302
 None
 1.00A 5flcB-3dknA:
undetectable		 5flcB-3dknA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3etc AMP-BINDING PROTEIN

(Methanosarcina
acetivorans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 GLU A 328
PHE A 350
GLY A 349
THR A 433
 None
1PE  A 994 ( 4.2A)
None
None
 0.86A 5flcB-3etcA:
undetectable		 5flcB-3etcA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7o SERINE PROTEASE

(Purpureocillium
lilacinum) 		PF00082
(Peptidase_S8) 		4 PHE A  51
GLY A  53
THR A  74
TYR A  85
 None
 0.93A 5flcB-3f7oA:
undetectable		 5flcB-3f7oA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 GLY A 329
THR A  64
TYR A 456
PHE A 459
 None
None
None
PG4  A   1 (-4.6A)
 0.90A 5flcB-3fdhA:
5.4		 5flcB-3fdhA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fw8 RETICULINE OXIDASE

(Eschscholzia
californica) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 GLU A 330
GLY A 337
THR A 144
TYR A 150
 None
 0.90A 5flcB-3fw8A:
undetectable		 5flcB-3fw8A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hj9 OXIDOREDUCTASE

(Cupriavidus
pinatubonensis) 		PF00881
(Nitroreductase) 		4 GLU A 156
SER A 159
GLY A 164
THR A  91
 None
 0.85A 5flcB-3hj9A:
undetectable		 5flcB-3hj9A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hyi PROTEIN DUF199/WHIA

(Thermotoga
maritima) 		PF02650
(HTH_WhiA)
PF10298
(WhiA_N)
PF14527
(LAGLIDADG_WhiA) 		4 GLU A  27
SER A  30
PHE A 114
GLY A 117
 None
 0.98A 5flcB-3hyiA:
undetectable		 5flcB-3hyiA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hyj PROTEIN DUF199/WHIA

(Thermotoga
maritima) 		PF10298
(WhiA_N)
PF14527
(LAGLIDADG_WhiA) 		4 GLU A  27
SER A  30
PHE A 114
GLY A 117
 None
 0.93A 5flcB-3hyjA:
undetectable		 5flcB-3hyjA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifw UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L1

(Homo sapiens) 		PF01088
(Peptidase_C12) 		4 GLU A 174
PHE A 162
GLY A  94
PHE A 204
 None
 1.00A 5flcB-3ifwA:
undetectable		 5flcB-3ifwA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-PROCESSING
FACTOR 17
PRE-MRNA-SPLICING
FACTOR CWF5

(Schizosaccharomyces
pombe) 		PF01423
(LSM)
PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 GLU g  92
PHE a  19
THR g  86
TYR g  88
 None
 0.99A 5flcB-3jb9g:
undetectable		 5flcB-3jb9g:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju5 ARGININE KINASE

(Apostichopus
japonicus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 GLU A 222
SER A 133
GLY A  68
PHE A 192
 None
 0.96A 5flcB-3ju5A:
undetectable		 5flcB-3ju5A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2n PEPTIDASE M14,
CARBOXYPEPTIDASE A

(Shewanella
denitrificans) 		PF00246
(Peptidase_M14) 		4 GLU A 228
GLY A 210
THR A 145
TYR A 242
 None
 1.00A 5flcB-3l2nA:
undetectable		 5flcB-3l2nA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lue ALPHA-ACTININ-3

(Homo sapiens) 		PF00307
(CH) 		4 PHE K  73
GLY K  76
THR K  52
PHE K 148
 None
 1.00A 5flcB-3lueK:
undetectable		 5flcB-3lueK:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m07 PUTATIVE ALPHA
AMYLASE

(Salmonella
enterica) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 GLY A 190
THR A  99
TRP A 100
PHE A 181
 None
 0.83A 5flcB-3m07A:
undetectable		 5flcB-3m07A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcu DIPICOLINATE
SYNTHASE, B CHAIN

(Bacillus cereus) 		PF02441
(Flavoprotein) 		4 GLU A  62
PHE A  10
GLY A   9
TYR A  19
 None
 0.94A 5flcB-3mcuA:
undetectable		 5flcB-3mcuA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oee ATP SYNTHASE SUBUNIT
ALPHA

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 GLU A 459
PHE A 466
GLY A 464
THR A 503
 None
 1.00A 5flcB-3oeeA:
1.9		 5flcB-3oeeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oee ATP SYNTHASE SUBUNIT
ALPHA

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 SER A 469
PHE A 466
GLY A 464
THR A 503
 None
 0.95A 5flcB-3oeeA:
1.9		 5flcB-3oeeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B

(Azoarcus
evansii) 		no annotation 4 SER A 293
GLY A 394
THR A 389
PHE A 290
 None
 0.90A 5flcB-3pf7A:
1.8		 5flcB-3pf7A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qlt GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 2

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 GLU A 268
GLY A 283
THR A 287
TYR A 293
 None
 0.80A 5flcB-3qltA:
undetectable		 5flcB-3qltA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u95 GLYCOSIDE HYDROLASE,
FAMILY 4

(Thermotoga
neapolitana) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 GLU A 296
GLY A 106
THR A 127
TRP A  99
 None
 0.96A 5flcB-3u95A:
undetectable		 5flcB-3u95A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vxi DYP

(Bjerkandera
adusta) 		PF04261
(Dyp_perox) 		5 GLU A 391
PHE A 305
GLY A 403
THR A 298
TYR A 293
 None
 1.42A 5flcB-3vxiA:
undetectable		 5flcB-3vxiA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5v PUTATIVE THUA-LIKE
PROTEIN

(Parabacteroides
merdae) 		PF06283
(ThuA) 		4 GLU A  97
PHE A  75
GLY A  74
THR A  34
 None
EDO  A 406 ( 4.8A)
None
None
 0.97A 5flcB-4e5vA:
undetectable		 5flcB-4e5vA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA

(Azotobacter
vinelandii) 		PF00696
(AA_kinase) 		4 GLU B 178
GLY B 130
THR B  76
PHE B 174
 None
8M0  B 302 (-3.8A)
None
None
 0.91A 5flcB-4f6tB:
undetectable		 5flcB-4f6tB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fay MICROCOMPARTMENTS
PROTEIN

(Lactobacillus
reuteri) 		PF00936
(BMC) 		4 GLU A  66
PHE A 119
GLY A 120
THR A  55
 None
None
None
GOL  A 304 (-4.6A)
 0.98A 5flcB-4fayA:
2.0		 5flcB-4fayA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4im4 ENDOGLUCANASE E

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		4 GLU A 123
GLY A 114
THR A 108
TRP A 109
 None
 0.89A 5flcB-4im4A:
0.7		 5flcB-4im4A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixu ARGINASE-2,
MITOCHONDRIAL

(Homo sapiens) 		PF00491
(Arginase) 		4 SER A 322
PHE A 323
GLY A 324
PHE A 250
 None
 0.92A 5flcB-4ixuA:
undetectable		 5flcB-4ixuA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jup CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11

(Homo sapiens) 		PF00619
(CARD) 		4 PHE A  91
GLY A  87
TYR A  98
PHE A  97
 None
 0.98A 5flcB-4jupA:
undetectable		 5flcB-4jupA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ku4 RAS-3 FROM
CRYPHONECTRIA
PARASITICA

(Cryphonectria
parasitica) 		PF00071
(Ras) 		4 GLU A 170
GLY A 176
THR A  25
PHE A  90
 None
None
MG  A 302 ( 3.2A)
None
 0.97A 5flcB-4ku4A:
undetectable		 5flcB-4ku4A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8v ALGINATE
BIOSYNTHESIS PROTEIN
ALGJ

(Pseudomonas
putida) 		PF16822
(ALGX) 		4 GLU A 177
GLY A 197
THR A 189
TYR A 141
 None
 0.84A 5flcB-4o8vA:
undetectable		 5flcB-4o8vA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ouj HEMAGGLUTININ
COMPONENT HA33

(Clostridium
botulinum) 		PF14200
(RicinB_lectin_2) 		4 SER A  65
THR A  17
TRP A  50
TYR A  29
 None
 0.97A 5flcB-4oujA:
undetectable		 5flcB-4oujA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST

(Escherichia
coli) 		PF05935
(Arylsulfotrans)
PF17425
(Arylsulfotran_N) 		4 SER A 502
PHE A 516
GLY A 515
THR A 137
 None
 0.92A 5flcB-4p05A:
undetectable		 5flcB-4p05A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pcg VP1

(Human
polyomavirus 6) 		PF00718
(Polyoma_coat) 		4 SER A 219
PHE A 220
GLY A 221
THR A 110
 None
 0.93A 5flcB-4pcgA:
undetectable		 5flcB-4pcgA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqx UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		PF12667
(NigD_N)
PF17415
(NigD_C) 		4 SER A  66
GLY A  70
TYR A  52
PHE A  62
 None
 0.92A 5flcB-4pqxA:
undetectable		 5flcB-4pqxA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pug BOLA LIKE PROTEIN

(Arabidopsis
thaliana) 		PF01722
(BolA) 		4 GLU A 107
SER A  91
GLY A  96
PHE A 110
 None
 0.85A 5flcB-4pugA:
undetectable		 5flcB-4pugA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdr NEUROPILIN-2

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		4 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
 0.88A 5flcB-4qdrA:
undetectable		 5flcB-4qdrA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qds NEUROPILIN-2

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		4 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
 0.99A 5flcB-4qdsA:
undetectable		 5flcB-4qdsA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qku HYDROLASE

(Burkholderia
cenocepacia) 		PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N) 		4 PHE A  29
GLY A  53
TRP A 277
PHE A  36
 None
 0.91A 5flcB-4qkuA:
undetectable		 5flcB-4qkuA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r70 BACTERIOPHYTOCHROME
(LIGHT-REGULATED
SIGNAL TRANSDUCTION
HISTIDINE KINASE),
PHYB2

(Rhodopseudomonas
palustris) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		5 GLU A 366
SER A 365
PHE A 388
GLY A 376
THR A 358
 None
 1.08A 5flcB-4r70A:
undetectable		 5flcB-4r70A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rf3 NADPH DEPENDENT
R-SPECIFIC ALCOHOL
DEHYDROGENASE

(Lactobacillus
kefiri) 		PF13561
(adh_short_C2) 		4 PHE A  81
GLY A  82
THR A  54
PHE A  27
 None
 0.99A 5flcB-4rf3A:
1.8		 5flcB-4rf3A:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3q 17 KDA LIPOPROTEIN

(Treponema
pallidum) 		PF04170
(NlpE) 		4 GLU A  80
GLY A  69
THR A  40
TYR A 108
 None
 0.95A 5flcB-4u3qA:
undetectable		 5flcB-4u3qA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uek GALACTITOL-1-PHOSPHA
TE 5-DEHYDROGENASE

(Escherichia
coli) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLU A 144
GLY A 296
TYR A 106
PHE A 108
 TRS  A1350 (-2.6A)
None
None
None
 0.86A 5flcB-4uekA:
undetectable		 5flcB-4uekA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uri CHITINASE-RELATED
AGGLUTININ

(Robinia
pseudoacacia) 		PF00704
(Glyco_hydro_18) 		4 GLY A 249
THR A 195
TRP A 240
TYR A 188
 None
 1.00A 5flcB-4uriA:
undetectable		 5flcB-4uriA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy5 ESTERASE

(Rhizomucor
miehei) 		PF07859
(Abhydrolase_3) 		4 GLU A 267
SER A 202
PHE A 206
GLY A 207
 None
 0.84A 5flcB-4wy5A:
undetectable		 5flcB-4wy5A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		4 PHE A 452
GLY A 453
THR A 519
TYR A 502
 None
GOL  A 803 (-3.6A)
None
None
 0.92A 5flcB-4yw5A:
undetectable		 5flcB-4yw5A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgf UNCHARACTERIZED
PROTEIN

(Bacteroides
vulgatus) 		PF16139
(DUF4847) 		4 GLU A  27
GLY A  32
THR A  88
TRP A 102
 None
P6G  A 205 (-3.3A)
P6G  A 207 (-4.0A)
None
 0.90A 5flcB-4zgfA:
undetectable		 5flcB-4zgfA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpd RNA-DIRECTED RNA
POLYMERASE

(Enterovirus B) 		PF00680
(RdRP_1) 		4 PHE A 191
GLY A 192
THR A 263
TYR A 268
 None
 0.98A 5flcB-4zpdA:
undetectable		 5flcB-4zpdA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4b HUMAN
ALPHA-ACTININ-2

(Homo sapiens) 		PF00307
(CH) 		4 PHE A  66
GLY A  69
THR A  45
PHE A 141
 None
 0.94A 5flcB-5a4bA:
undetectable		 5flcB-5a4bA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT
2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF02775
(TPP_enzyme_C)
PF12367
(PFO_beta_C)
PF17147
(PFOR_II) 		4 GLU A 292
GLY B  91
THR A 257
TYR A 253
 None
TPP  B 402 (-3.4A)
PYR  A 701 (-3.0A)
None
 0.96A 5flcB-5b47A:
undetectable		 5flcB-5b47A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c04 PUTATIVE
PEROXIREDOXIN MT2298

(Mycobacterium
tuberculosis) 		PF00578
(AhpC-TSA) 		4 GLU A 131
GLY A 105
THR A   7
PHE A 129
 None
 0.94A 5flcB-5c04A:
undetectable		 5flcB-5c04A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn2 NEUROPILIN-2

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		4 GLY A 346
THR A 305
TRP A 318
TYR A 299
 None
 0.87A 5flcB-5dn2A:
undetectable		 5flcB-5dn2A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzq TOXIN-LIKE PROTEIN

(Paenibacillus
larvae) 		PF03496
(ADPrib_exo_Tox) 		4 GLU A  24
THR A 119
TYR A 116
PHE A  32
 None
 0.98A 5flcB-5dzqA:
undetectable		 5flcB-5dzqA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eoe BETA-LACTAMASE

(Pseudomonas
aeruginosa) 		PF13354
(Beta-lactamase2) 		4 SER A 184
PHE A 188
GLY A 189
TYR A 250
 None
 0.96A 5flcB-5eoeA:
undetectable		 5flcB-5eoeA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5equ SNON,SNON

(Streptomyces
nogalater) 		PF05721
(PhyH) 		4 GLU A  60
GLY A  81
THR A 227
TYR A  74
 None
None
None
5R6  A 302 (-3.5A)
 0.97A 5flcB-5equA:
undetectable		 5flcB-5equA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5euf PROTEASE

(Helicobacter
pylori) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 PHE A 324
GLY A 302
TYR A 172
PHE A 175
 None
 0.71A 5flcB-5eufA:
undetectable		 5flcB-5eufA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g52 VP1
VP3

(Deformed wing
virus) 		PF00073
(Rhv)
PF08762
(CRPV_capsid) 		4 PHE A  26
GLY A  27
TRP C 186
PHE C 114
 None
 0.72A 5flcB-5g52A:
undetectable		 5flcB-5g52A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghf AMINOTRANSFERASE
CLASS-III

(Ochrobactrum
anthropi) 		PF00202
(Aminotran_3) 		4 GLU A 189
GLY A 231
TYR A 240
PHE A 199
 None
 1.00A 5flcB-5ghfA:
undetectable		 5flcB-5ghfA:
17.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		5 GLU A2032
SER A2035
GLY A2040
THR A2098
TRP A2101
 None
 1.48A 5flcB-5h64A:
undetectable		 5flcB-5h64A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		5 GLU A2032
SER A2035
GLY A2040
TRP A2101
PHE A2108
 None
 1.12A 5flcB-5h64A:
undetectable		 5flcB-5h64A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		5 GLU A2032
SER A2035
PHE A2039
GLY A2040
TRP A2101
 None
 1.31A 5flcB-5h64A:
undetectable		 5flcB-5h64A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb3 NUCLEOPORIN NIC96

(Chaetomium
thermophilum) 		PF04097
(Nic96) 		4 GLU A 895
GLY A 838
THR A 885
TYR A 891
 None
 0.88A 5flcB-5hb3A:
undetectable		 5flcB-5hb3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzg STRIGOLACTONE
ESTERASE D14

(Arabidopsis
thaliana) 		PF12697
(Abhydrolase_6) 		4 PHE A  28
GLY A  29
TYR A  69
PHE A  66
 6OM  A 301 (-4.3A)
None
None
None
 0.89A 5flcB-5hzgA:
undetectable		 5flcB-5hzgA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 GLU B 780
GLY A 602
THR B 805
TRP B 806
 None
 0.93A 5flcB-5jpnB:
undetectable		 5flcB-5jpnB:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 GLY A1800
TRP A1806
TYR A1813
PHE A1812
 None
 0.88A 5flcB-5m59A:
undetectable		 5flcB-5m59A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9w THEBAINE
6-O-DEMETHYLASE

(Papaver
somniferum) 		no annotation 4 GLU A 283
GLY A 243
THR A 340
PHE A 335
 None
 0.97A 5flcB-5o9wA:
undetectable		 5flcB-5o9wA:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ti1 FUMARYLACETOACETATE
HYDROLASE

(Paraburkholderia
xenovorans) 		PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N) 		4 PHE A  29
GLY A  54
TRP A 281
PHE A  36
 None
 1.00A 5flcB-5ti1A:
undetectable		 5flcB-5ti1A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vad BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE

(Homo sapiens) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1) 		4 GLU A1198
GLY A1238
THR A1284
PHE A1413
 None
 0.98A 5flcB-5vadA:
undetectable		 5flcB-5vadA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whz ANTI-HIV CODV-FAB
LIGHT CHAIN

(Homo sapiens) 		no annotation 4 SER L 151
GLY L 167
THR L 139
PHE L 218
 None
 0.96A 5flcB-5whzL:
undetectable		 5flcB-5whzL:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8t 50S RIBOSOMAL
PROTEIN L31

(Spinacia
oleracea) 		PF01197
(Ribosomal_L31) 		4 GLU 0  71
GLY 0  75
THR 0  60
TYR 0  52
 None
 0.93A 5flcB-5x8t0:
undetectable		 5flcB-5x8t0:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhb NISIN IMMUNITY
PROTEIN

(Lactococcus
lactis) 		no annotation 5 GLU A 171
SER A 219
GLY A 222
THR A 241
TYR A 152
 None
 1.31A 5flcB-5xhbA:
undetectable		 5flcB-5xhbA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xv5 CONSERVED PROTEIN

(Methanosarcina
mazei) 		no annotation 4 GLU A 173
GLY A 225
THR A 139
PHE A   5
 None
 0.99A 5flcB-5xv5A:
undetectable		 5flcB-5xv5A:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y59 ATP-DEPENDENT DNA
HELICASE II SUBUNIT
2

(Saccharomyces
cerevisiae) 		no annotation 4 PHE B  83
GLY B  82
TYR B  49
PHE B  66
 None
 0.92A 5flcB-5y59B:
undetectable		 5flcB-5y59B:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6avh GH3.15 ACYL ACID
AMIDO SYNTHETASE

(Arabidopsis
thaliana) 		no annotation 4 GLU A 456
GLY A 485
THR A 466
TRP A 482
 None
 0.98A 5flcB-6avhA:
undetectable		 5flcB-6avhA:
5.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 1

(Homo sapiens) 		no annotation 4 PHE C 914
GLY C 913
THR C 935
TYR C 928
 None
 0.91A 5flcB-6en4C:
undetectable		 5flcB-6en4C:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 SER A2038
PHE A2039
GLY A2041
PHE A2047
 None
 0.95A 5flcB-6fb3A:
undetectable		 5flcB-6fb3A:
5.31