SIMILAR PATTERNS OF AMINO ACIDS FOR 5F1A_A_SALA601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a87 | COLICIN N (Escherichiacoli) |
PF01024(Colicin) | 4 | LEU A 366GLY A 339ALA A 340SER A 343 | None | 0.57A | 5f1aA-1a87A:0.0 | 5f1aA-1a87A:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bhd | UTROPHIN (Homo sapiens) |
PF00307(CH) | 4 | VAL A 253LEU A 254LEU A 196ALA A 218 | None | 0.75A | 5f1aA-1bhdA:undetectable | 5f1aA-1bhdA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bxk | PROTEIN(DTDP-GLUCOSE4,6-DEHYDRATASE) (Escherichiacoli) |
PF16363(GDP_Man_Dehyd) | 4 | LEU A 287TYR A 284GLY A 211ALA A 210 | None | 0.77A | 5f1aA-1bxkA:undetectable | 5f1aA-1bxkA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg2 | CARBOXYPEPTIDASE G2 (Pseudomonas sp.RS-16) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | LEU A 107TYR A 195GLY A 412ALA A 413 | None | 0.65A | 5f1aA-1cg2A:undetectable | 5f1aA-1cg2A:22.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 6 | VAL A 349LEU A 352LEU A 384TYR A 385TRP A 387GLY A 526 | SCL A 700 ( 4.6A)SCL A 700 ( 4.8A)NoneNoneNoneSCL A 700 ( 4.0A) | 0.63A | 5f1aA-1ebvA:58.7 | 5f1aA-1ebvA:63.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 6 | VAL A 349LEU A 384TYR A 385TRP A 387GLY A 526ALA A 527 | SCL A 700 ( 4.6A)NoneNoneNoneSCL A 700 ( 4.0A)SCL A 700 (-2.9A) | 0.35A | 5f1aA-1ebvA:58.7 | 5f1aA-1ebvA:63.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htt | HISTIDYL-TRNASYNTHETASE (Escherichiacoli) |
PF03129(HGTP_anticodon)PF13393(tRNA-synt_His) | 4 | LEU A 43TYR A 107GLY A 87ALA A 86 | None | 0.65A | 5f1aA-1httA:0.0 | 5f1aA-1httA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iah | TRANSIENT RECEPTORPOTENTIAL-RELATEDPROTEIN (Mus musculus) |
PF02816(Alpha_kinase) | 4 | LEU A1706GLY A1712ALA A1711SER A1710 | None | 0.78A | 5f1aA-1iahA:0.0 | 5f1aA-1iahA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j2b | ARCHAEOSINETRNA-GUANINETRANSGLYCOSYLASE (Pyrococcushorikoshii) |
PF01472(PUA)PF01702(TGT)PF14809(TGT_C1)PF14810(TGT_C2) | 4 | LEU A 349LEU A 328TRP A 329ALA A 240 | None | 0.81A | 5f1aA-1j2bA:0.0 | 5f1aA-1j2bA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jct | GLUCARATEDEHYDRATASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 4 | VAL A 132LEU A 136LEU A 84ALA A 118 | None | 0.79A | 5f1aA-1jctA:0.0 | 5f1aA-1jctA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mda | METHYLAMINEDEHYDROGENASE (HEAVYSUBUNIT) (Paracoccusdenitrificans) |
PF06433(Me-amine-dh_H) | 4 | VAL H 98LEU H 161GLY H 150SER H 152 | None | 0.80A | 5f1aA-1mdaH:0.0 | 5f1aA-1mdaH:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4t | EXOENZYME S (Pseudomonasaeruginosa) |
PF03545(YopE) | 4 | VAL A 195LEU A 202GLY A 130ALA A 132 | None | 0.73A | 5f1aA-1r4tA:undetectable | 5f1aA-1r4tA:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlt | PUTATIVEOXIDOREDUCTASE(VIRULENCE FACTORMVIM HOMOLOG) (Escherichiacoli) |
PF01408(GFO_IDH_MocA) | 4 | VAL A 81LEU A 59GLY A 12SER A 73 | None | 0.74A | 5f1aA-1tltA:undetectable | 5f1aA-1tltA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6z | EXOPOLYPHOSPHATASE (Escherichiacoli) |
PF02541(Ppx-GppA) | 4 | LEU A 290GLY A 215ALA A 216SER A 293 | None | 0.82A | 5f1aA-1u6zA:undetectable | 5f1aA-1u6zA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vey | PEPTIDE DEFORMYLASE (Leptospirainterrogans) |
PF01327(Pep_deformylase) | 4 | VAL A 154LEU A 157LEU A 169GLY A 164 | None | 0.83A | 5f1aA-1veyA:undetectable | 5f1aA-1veyA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xov | PLY PROTEIN (Listeria virusPSA) |
PF01520(Amidase_3) | 4 | LEU A 21LEU A 163TYR A 160ALA A 153 | None | 0.81A | 5f1aA-1xovA:undetectable | 5f1aA-1xovA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z3v | CELLULASE (Phanerochaetechrysosporium) |
PF00840(Glyco_hydro_7) | 4 | LEU A 374LEU A 133GLY A 139ALA A 140 | None | 0.76A | 5f1aA-1z3vA:undetectable | 5f1aA-1z3vA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z72 | TRANSCRIPTIONALREGULATOR, PUTATIVE (Streptococcuspneumoniae) |
PF03070(TENA_THI-4) | 4 | LEU A 142LEU A 85GLY A 66ALA A 67 | None | 0.81A | 5f1aA-1z72A:0.4 | 5f1aA-1z72A:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2col | BIFUNCTIONALHEMOLYSIN-ADENYLATECYCLASE (Bordetellapertussis) |
PF03497(Anthrax_toxA) | 4 | LEU A 113GLY A 74ALA A 73SER A 67 | None | 0.83A | 5f1aA-2colA:undetectable | 5f1aA-2colA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2elc | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Thermusthermophilus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | VAL A 215LEU A 74GLY A 290ALA A 289 | None | 0.73A | 5f1aA-2elcA:undetectable | 5f1aA-2elcA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g28 | PYRUVATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00456(Transketolase_N) | 4 | LEU A 610GLY A 575ALA A 574SER A 577 | None | 0.82A | 5f1aA-2g28A:undetectable | 5f1aA-2g28A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j89 | METHIONINE SULFOXIDEREDUCTASE A (Populustrichocarpa) |
PF01625(PMSR) | 4 | LEU A 180TYR A 179TRP A 48GLY A 204 | NoneNoneBME A 207 ( 4.2A)None | 0.76A | 5f1aA-2j89A:undetectable | 5f1aA-2j89A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpw | HYPOTHETICALMEMBRANE SPANNINGPROTEIN (Thermusthermophilus) |
PF14589(NrfD_2) | 4 | LEU C 176LEU C 184GLY C 217ALA C 230 | None | 0.73A | 5f1aA-2vpwC:undetectable | 5f1aA-2vpwC:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wpg | AMYLOSUCRASE ORALPHA AMYLASE (Xanthomonascampestris) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 4 | LEU A 478GLY A 357ALA A 356SER A 359 | None | 0.80A | 5f1aA-2wpgA:undetectable | 5f1aA-2wpgA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wua | ACETOACETYL COATHIOLASE (Helianthusannuus) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | VAL A 277LEU A 271GLY A 287ALA A 286SER A 289 | None | 1.18A | 5f1aA-2wuaA:undetectable | 5f1aA-2wuaA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ycj | 5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE (Carboxydothermushydrogenoformans) |
PF00809(Pterin_bind) | 4 | LEU A 163LEU A 144GLY A 122SER A 98 | None | 0.83A | 5f1aA-2ycjA:undetectable | 5f1aA-2ycjA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3auo | DNA POLYMERASE BETAFAMILY (X FAMILY) (Thermusthermophilus) |
PF14520(HHH_5)PF14716(HHH_8)PF14791(DNA_pol_B_thumb) | 4 | LEU A 202GLY A 255ALA A 254SER A 251 | None | 0.75A | 5f1aA-3auoA:undetectable | 5f1aA-3auoA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cze | SUCROSE HYDROLASE (Xanthomonascitri) |
PF00128(Alpha-amylase) | 4 | LEU A 477GLY A 356ALA A 355SER A 358 | None | 0.77A | 5f1aA-3czeA:undetectable | 5f1aA-3czeA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gi8 | UNCHARACTERIZEDPROTEIN MJ0609 (Methanocaldococcusjannaschii) |
PF13520(AA_permease_2) | 4 | LEU C 162GLY C 279ALA C 280SER C 283 | None | 0.72A | 5f1aA-3gi8C:undetectable | 5f1aA-3gi8C:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gmt | ADENYLATE KINASE (Burkholderiapseudomallei) |
PF00406(ADK)PF05191(ADK_lid) | 5 | VAL A 68LEU A 72LEU A 194GLY A 100ALA A 99 | None | 1.24A | 5f1aA-3gmtA:undetectable | 5f1aA-3gmtA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hlm | ASPARTATEAMINOTRANSFERASE,MITOCHONDRIAL (Mus musculus) |
PF00155(Aminotran_1_2) | 4 | VAL A 129TYR A 316GLY A 136ALA A 137 | None | 0.68A | 5f1aA-3hlmA:undetectable | 5f1aA-3hlmA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7y | MS30 (Homo sapiens) |
PF00829(Ribosomal_L21p) | 4 | LEU s 80LEU s 377GLY s 337ALA s 338 | None | 0.66A | 5f1aA-3j7ys:undetectable | 5f1aA-3j7ys:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb5 | MAJOR CAPSID PROTEIN (Propionibacteriumvirus PA6) |
no annotation | 4 | LEU A 122GLY A 229ALA A 230SER A 225 | None | 0.80A | 5f1aA-3jb5A:undetectable | 5f1aA-3jb5A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jui | TRANSLATIONINITIATION FACTOREIF-2B SUBUNITEPSILON (Homo sapiens) |
PF02020(W2) | 4 | LEU A 646LEU A 710GLY A 678ALA A 677 | None | 0.58A | 5f1aA-3juiA:2.0 | 5f1aA-3juiA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldz | SIGNAL TRANSDUCINGADAPTER MOLECULE 1 (Homo sapiens) |
PF00790(VHS) | 4 | LEU A 111GLY A 70ALA A 71SER A 74 | None | 0.65A | 5f1aA-3ldzA:undetectable | 5f1aA-3ldzA:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nxl | GLUCARATEDEHYDRATASE (Burkholderialata) |
PF13378(MR_MLE_C) | 4 | VAL A 152LEU A 156LEU A 88ALA A 138 | None | 0.76A | 5f1aA-3nxlA:undetectable | 5f1aA-3nxlA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oc4 | OXIDOREDUCTASE,PYRIDINENUCLEOTIDE-DISULFIDEFAMILY (Enterococcusfaecalis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 30GLY A 12ALA A 11SER A 14 | NoneNoneFAD A 500 (-3.3A)None | 0.76A | 5f1aA-3oc4A:undetectable | 5f1aA-3oc4A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ovk | AMINOPEPTIDASE P,XAA-PRO DIPEPTIDASE (Streptococcuspyogenes) |
PF01321(Creatinase_N) | 4 | VAL A 83LEU A 87LEU A 21GLY A 96 | None | 0.58A | 5f1aA-3ovkA:undetectable | 5f1aA-3ovkA:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0w | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Ralstoniapickettii) |
PF13378(MR_MLE_C) | 4 | VAL A 148LEU A 152LEU A 84ALA A 134 | None | 0.77A | 5f1aA-3p0wA:undetectable | 5f1aA-3p0wA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r8x | METHIONYL-TRNAFORMYLTRANSFERASE (Yersinia pestis) |
PF00551(Formyl_trans_N)PF02911(Formyl_trans_C) | 4 | LEU A 55GLY A 21ALA A 22SER A 25 | None | 0.65A | 5f1aA-3r8xA:undetectable | 5f1aA-3r8xA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rza | TRIPEPTIDASE (Staphylococcusaureus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | VAL A 138LEU A 53GLY A 149ALA A 150 | None | 0.60A | 5f1aA-3rzaA:undetectable | 5f1aA-3rzaA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swg | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aquifexaeolicus) |
PF00275(EPSP_synthase) | 4 | LEU A 273LEU A 384GLY A 248ALA A 249 | None | 0.83A | 5f1aA-3swgA:undetectable | 5f1aA-3swgA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t33 | G PROTEIN COUPLEDRECEPTOR (Arabidopsisthaliana) |
PF05147(LANC_like) | 4 | LEU A 80TYR A 73GLY A 127ALA A 126 | None | 0.71A | 5f1aA-3t33A:undetectable | 5f1aA-3t33A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ufg | GLYCYL-TRNASYNTHETASE ALPHASUBUNIT (Campylobacterjejuni) |
PF02091(tRNA-synt_2e) | 4 | VAL A 145LEU A 283GLY A 44SER A 42 | None | 0.66A | 5f1aA-3ufgA:undetectable | 5f1aA-3ufgA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v94 | CYCLIC NUCLEOTIDESPECIFICPHOSPHODIESTERASE (Trypanosomacruzi) |
PF00233(PDEase_I) | 4 | LEU A 584GLY A 493ALA A 494SER A 497 | None | 0.62A | 5f1aA-3v94A:undetectable | 5f1aA-3v94A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x0y | DSZC (Rhodococcuserythropolis) |
PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 4 | LEU A 93GLY A 164ALA A 165SER A 168 | None | 0.81A | 5f1aA-3x0yA:0.0 | 5f1aA-3x0yA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a9w | MONOOXYGENASE (Stenotrophomonasmaltophilia) |
PF13738(Pyr_redox_3) | 5 | VAL A 336LEU A 91TYR A 85GLY A 19ALA A 18 | None | 1.16A | 5f1aA-4a9wA:undetectable | 5f1aA-4a9wA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b3n | MALTOSE-BINDINGPERIPLASMIC PROTEIN,TRIPARTITEMOTIF-CONTAININGPROTEIN 5 (Escherichiacoli;Macaca mulatta) |
PF00622(SPRY)PF01547(SBP_bac_1) | 4 | LEU A 76GLY A 265ALA A 264SER A 263 | None | 0.83A | 5f1aA-4b3nA:undetectable | 5f1aA-4b3nA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dwq | TRNA-SPLICING LIGASERTCB (Pyrococcushorikoshii) |
PF01139(RtcB) | 4 | VAL A 147LEU A 148GLY A 191ALA A 192 | None | 0.72A | 5f1aA-4dwqA:undetectable | 5f1aA-4dwqA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dxb | MALTOSE-BINDINGPERIPLASMIC PROTEIN,BETA-LACTAMASE TEMCHIMERA (Escherichiacoli) |
PF01547(SBP_bac_1)PF13354(Beta-lactamase2) | 4 | LEU A 76GLY A 265ALA A 264SER A 263 | None | 0.83A | 5f1aA-4dxbA:undetectable | 5f1aA-4dxbA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hn8 | D-GLUCARATEDEHYDRATASE (Pseudomonasmendocina) |
PF13378(MR_MLE_C) | 4 | VAL A 149LEU A 153LEU A 86ALA A 135 | None | 0.77A | 5f1aA-4hn8A:undetectable | 5f1aA-4hn8A:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hqb | SINGLE-STRANDEDDNA-BINDING PROTEINDDRB (Deinococcusradiodurans) |
PF12747(DdrB) | 4 | VAL A 115TYR A 82GLY A 106ALA A 107 | None | 0.73A | 5f1aA-4hqbA:undetectable | 5f1aA-4hqbA:13.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4inz | SOLUBLE EPOXIDEHYDROLASE (Bacillusmegaterium) |
PF00561(Abhydrolase_1) | 4 | LEU A 93LEU A 55GLY A 99ALA A 100 | None | 0.71A | 5f1aA-4inzA:undetectable | 5f1aA-4inzA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j57 | THIOREDOXINREDUCTASE 2 (Plasmodiumfalciparum) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | VAL A 73LEU A 69TYR A 156GLY A 49 | FAD A 601 (-3.5A)NoneNoneFAD A 601 ( 4.8A) | 0.75A | 5f1aA-4j57A:1.3 | 5f1aA-4j57A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jxu | PUTATIVEAMINOTRANSFERASE (Sinorhizobiummeliloti) |
PF01063(Aminotran_4) | 4 | LEU A 139LEU A 169GLY A 193SER A 195 | None | 0.67A | 5f1aA-4jxuA:undetectable | 5f1aA-4jxuA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4om9 | SERINE PROTEASE PET (Escherichiacoli) |
PF02395(Peptidase_S6) | 4 | LEU A 171GLY A 57ALA A 58SER A 210 | None | 0.72A | 5f1aA-4om9A:undetectable | 5f1aA-4om9A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqy | (S)-IMINE REDUCTASE (Streptomycessp. GF3546) |
PF03446(NAD_binding_2) | 4 | LEU A 285LEU A 234GLY A 268ALA A 267 | None | 0.81A | 5f1aA-4oqyA:undetectable | 5f1aA-4oqyA:18.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ph9 | PROSTAGLANDIN G/HSYNTHASE 2 (Mus musculus) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | LEU A 353LEU A 385TYR A 386TRP A 388GLY A 527 | IBP A 601 ( 4.7A)NoneIBP A 601 (-4.8A)NoneIBP A 601 (-3.9A) | 0.69A | 5f1aA-4ph9A:63.4 | 5f1aA-4ph9A:88.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ph9 | PROSTAGLANDIN G/HSYNTHASE 2 (Mus musculus) |
PF00008(EGF)PF03098(An_peroxidase) | 6 | VAL A 350LEU A 385TYR A 386TRP A 388GLY A 527ALA A 528 | IBP A 601 (-4.3A)NoneIBP A 601 (-4.8A)NoneIBP A 601 (-3.9A)IBP A 601 (-3.4A) | 0.20A | 5f1aA-4ph9A:63.4 | 5f1aA-4ph9A:88.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ph9 | PROSTAGLANDIN G/HSYNTHASE 2 (Mus musculus) |
PF00008(EGF)PF03098(An_peroxidase) | 4 | VAL A 350TYR A 386ALA A 528SER A 531 | IBP A 601 (-4.3A)IBP A 601 (-4.8A)IBP A 601 (-3.4A)IBP A 601 ( 3.3A) | 0.74A | 5f1aA-4ph9A:63.4 | 5f1aA-4ph9A:88.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qjy | GH127BETA-L-ARABINOFURANOSIDASE (Geobacillusstearothermophilus) |
PF07944(Glyco_hydro_127) | 4 | LEU A 358LEU A 12GLY A 419SER A 417 | NoneNoneNoneACT A 703 ( 4.0A) | 0.80A | 5f1aA-4qjyA:undetectable | 5f1aA-4qjyA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkc | AROMATIC AMINO ACIDAMINOTRANSFERASE (Psychrobactersp. B6) |
PF00155(Aminotran_1_2) | 4 | VAL A 174LEU A 258GLY A 110ALA A 111 | None | 0.80A | 5f1aA-4rkcA:undetectable | 5f1aA-4rkcA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9i | PERIPLASMIC [NIFE]HYDROGENASE LARGESUBUNIT (Desulfovibriovulgaris) |
PF00374(NiFeSe_Hases) | 4 | VAL L 415LEU L 410LEU L 388GLY L 425 | None | 0.82A | 5f1aA-4u9iL:undetectable | 5f1aA-4u9iL:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubt | ACETYL-COAACETYLTRANSFERASEFADA5 (Mycobacteriumtuberculosis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | VAL A 234LEU A 228GLY A 243ALA A 242SER A 245 | NoneNoneCOA A 401 ( 4.3A)COA A 401 (-3.5A)COA A 401 ( 4.0A) | 0.99A | 5f1aA-4ubtA:undetectable | 5f1aA-4ubtA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upe | NICKEL-DEPENDENTHYDROGENASE LARGESUBUNIT (Desulfovibriofructosivorans) |
PF00374(NiFeSe_Hases) | 4 | VAL Q 413LEU Q 408LEU Q 386GLY Q 423 | None | 0.82A | 5f1aA-4upeQ:undetectable | 5f1aA-4upeQ:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wb0 | BROAD SPECIFICITYAMINOTRANSFERASE (Leishmaniamexicana) |
PF00155(Aminotran_1_2) | 4 | VAL A 105TYR A 294GLY A 112ALA A 113 | NoneCSO A 296 ( 4.6A)NoneNone | 0.73A | 5f1aA-4wb0A:undetectable | 5f1aA-4wb0A:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wb0 | BROAD SPECIFICITYAMINOTRANSFERASE (Leishmaniamexicana) |
PF00155(Aminotran_1_2) | 4 | VAL A 184LEU A 269GLY A 117ALA A 118 | None | 0.66A | 5f1aA-4wb0A:undetectable | 5f1aA-4wb0A:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjm | RIBOKINASE:CARBOHYDRATE KINASE, PFKB (Brucellaabortus) |
PF00294(PfkB) | 4 | LEU A 65LEU A 3ALA A 75SER A 50 | None | 0.79A | 5f1aA-4wjmA:undetectable | 5f1aA-4wjmA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxt | THIOREDOXIN (Mycobacteriumavium) |
PF00085(Thioredoxin) | 4 | VAL A 47LEU A 48GLY A 98ALA A 99 | None | 0.82A | 5f1aA-4wxtA:undetectable | 5f1aA-4wxtA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xsr | ALR3699 PROTEIN (Nostoc sp. PCC7120) |
no annotation | 4 | LEU B 6GLY B 105ALA B 106SER B 109 | None | 0.66A | 5f1aA-4xsrB:undetectable | 5f1aA-4xsrB:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ymw | ABC-TYPE AMINO ACIDTRANSPORT SYSTEM,PERMEASE COMPONENT (Caldanaerobactersubterraneus) |
no annotation | 4 | LEU D 25GLY D 91ALA D 90SER D 93 | None | 0.76A | 5f1aA-4ymwD:undetectable | 5f1aA-4ymwD:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a12 | CHLORITE DISMUTASE (Magnetospirillumsp.) |
PF06778(Chlor_dismutase) | 4 | LEU A 175GLY A 130ALA A 129SER A 132 | HEM A 250 ( 4.7A)NoneNoneNone | 0.81A | 5f1aA-5a12A:undetectable | 5f1aA-5a12A:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 4 | LEU A1405GLY A1467ALA A1468SER A1471 | None | 0.79A | 5f1aA-5a31A:undetectable | 5f1aA-5a31A:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bxp | LACTO-N-BIOSIDASE (Bifidobacteriumbifidum) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b)PF14200(RicinB_lectin_2) | 4 | LEU A 370GLY A 318ALA A 319SER A 260 | None | 0.80A | 5f1aA-5bxpA:undetectable | 5f1aA-5bxpA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cpg | (R)-SPECIFICENOYL-COA HYDRATASE (Pseudomonasaeruginosa) |
PF01575(MaoC_dehydratas) | 4 | LEU A 88GLY A 65ALA A 66SER A 69 | None | 0.54A | 5f1aA-5cpgA:undetectable | 5f1aA-5cpgA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csc | CITRATE SYNTHASE (Gallus gallus) |
PF00285(Citrate_synt) | 5 | VAL B 350LEU B 353TRP B 284GLY B 317ALA B 376 | None | 1.40A | 5f1aA-5cscB:undetectable | 5f1aA-5cscB:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e3i | HISTIDINE--TRNALIGASE (Acinetobacterbaumannii) |
PF03129(HGTP_anticodon)PF13393(tRNA-synt_His) | 4 | LEU A 43TYR A 109GLY A 89ALA A 88 | None | 0.73A | 5f1aA-5e3iA:undetectable | 5f1aA-5e3iA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ez3 | ACYL-COADEHYDROGENASE (Brucellamelitensis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M) | 4 | VAL A 390LEU A 507GLY A 358ALA A 359 | None | 0.82A | 5f1aA-5ez3A:0.1 | 5f1aA-5ez3A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g3y | ADENYLATE KINSE (syntheticconstruct) |
PF00406(ADK)PF05191(ADK_lid) | 4 | VAL A 63LEU A 67GLY A 46ALA A 49 | None | 0.82A | 5f1aA-5g3yA:undetectable | 5f1aA-5g3yA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7t | CLASS IV CHITINASE (Cryptomeriajaponica) |
no annotation | 4 | LEU A 124GLY A 113ALA A 114SER A 117 | None | 0.63A | 5f1aA-5h7tA:undetectable | 5f1aA-5h7tA:15.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hes | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE MLT (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | LEU A 47LEU A 57GLY A 153ALA A 154 | None032 A 401 ( 4.7A)032 A 401 (-3.6A)None | 0.78A | 5f1aA-5hesA:undetectable | 5f1aA-5hesA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hft | GAMMA-GLUTAMYLTRANSPEPTIDASE (Klebsiellapneumoniae) |
PF01019(G_glu_transpept) | 4 | LEU A 251GLY A 58ALA A 74SER A 75 | None | 0.80A | 5f1aA-5hftA:undetectable | 5f1aA-5hftA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i7n | MAOC-LIKEDEHYDRATASE (Mycobacteroidesabscessus) |
PF01575(MaoC_dehydratas)PF13452(MaoC_dehydrat_N) | 4 | VAL A 339LEU A 54GLY A 203SER A 275 | None | 0.79A | 5f1aA-5i7nA:undetectable | 5f1aA-5i7nA:21.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikr | PROSTAGLANDIN G/HSYNTHASE 2 (Homo sapiens) |
PF00008(EGF)PF03098(An_peroxidase) | 8 | VAL A 349LEU A 352LEU A 384TYR A 385TRP A 387GLY A 526ALA A 527SER A 530 | ID8 A 601 (-3.9A)ID8 A 601 (-4.1A)ID8 A 601 ( 4.8A)ID8 A 601 ( 3.5A)COH A 602 (-4.5A)ID8 A 601 (-3.5A)ID8 A 601 (-3.5A)ID8 A 601 (-2.7A) | 0.36A | 5f1aA-5ikrA:63.7 | 5f1aA-5ikrA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5in8 | ARISTOLOCHENESYNTHASE (Aspergillusterreus) |
no annotation | 4 | VAL A 272LEU A 275LEU A 190ALA A 286 | None | 0.72A | 5f1aA-5in8A:undetectable | 5f1aA-5in8A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3x | NEGATIVE ELONGATIONFACTOR C/D (Homo sapiens) |
PF04858(TH1) | 4 | LEU B 281GLY B 297ALA B 298SER B 301 | None | 0.52A | 5f1aA-5l3xB:1.6 | 5f1aA-5l3xB:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcw | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 4 | LEU A1405GLY A1467ALA A1468SER A1471 | None | 0.80A | 5f1aA-5lcwA:undetectable | 5f1aA-5lcwA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkk | MULTIDRUG RESISTANCEABC TRANSPORTERATP-BINDING ANDPERMEASE PROTEIN (Thermusthermophilus) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | LEU B 165LEU B 278GLY B 264ALA B 263 | None | 0.60A | 5f1aA-5mkkB:undetectable | 5f1aA-5mkkB:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nsq | AMINOPEPTIDASE,PUTATIVE (Trypanosomabrucei) |
PF00883(Peptidase_M17) | 4 | LEU A 378LEU A 496GLY A 315ALA A 316 | None | 0.56A | 5f1aA-5nsqA:undetectable | 5f1aA-5nsqA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swn | FLUOROACETATEDEHALOGENASE (Rhodopseudomonaspalustris) |
PF00561(Abhydrolase_1) | 4 | LEU A 106LEU A 65GLY A 112ALA A 113 | None | 0.58A | 5f1aA-5swnA:undetectable | 5f1aA-5swnA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u03 | CTP SYNTHASE 1 (Homo sapiens) |
PF00117(GATase)PF06418(CTP_synth_N) | 4 | VAL A 6LEU A 78TYR A 74GLY A 24 | None | 0.71A | 5f1aA-5u03A:undetectable | 5f1aA-5u03A:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w1j | THIOREDOXINGLUTATHIONEREDUCTASE (Echinococcusgranulosus) |
no annotation | 4 | VAL A 141LEU A 137TYR A 223GLY A 117 | FAD A 601 ( 3.8A)NoneNoneFAD A 601 (-4.4A) | 0.66A | 5f1aA-5w1jA:undetectable | 5f1aA-5w1jA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmd | EPOXIDE HYDROLASE A (Vigna radiata) |
no annotation | 4 | LEU A 97LEU A 59GLY A 103ALA A 104 | None | 0.66A | 5f1aA-5xmdA:undetectable | 5f1aA-5xmdA:11.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnw | ADENYLATE CYCLASEEXOY (Pseudomonasaeruginosa) |
no annotation | 4 | LEU A 137GLY A 97ALA A 96SER A 90 | None | 0.72A | 5f1aA-5xnwA:undetectable | 5f1aA-5xnwA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byn | WD REPEAT-CONTAININGPROTEIN 5 (Homo sapiens) |
no annotation | 4 | LEU W 249LEU W 209GLY W 246SER W 244 | None | 0.72A | 5f1aA-6bynW:undetectable | 5f1aA-6bynW:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5d | ATP SYNTHASE ALPHACHAIN, MITOCHONDRIALATP SYNTHASE GAMMASUBUNITATP SYNTHASE SUBUNITBETA (Trypanosomabrucei) |
no annotation | 4 | LEU A 297LEU G 284GLY D 278SER D 274 | None | 0.81A | 5f1aA-6f5dA:undetectable | 5f1aA-6f5dA:10.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fm9 | UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATEN-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (Homo sapiens) |
no annotation | 4 | LEU A 384GLY A 196ALA A 195SER A 198 | None | 0.83A | 5f1aA-6fm9A:undetectable | 5f1aA-6fm9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g21 | PROBABLE FERULOYLESTERASE B-2 (Aspergillusoryzae) |
no annotation | 4 | LEU A 101TYR A 98GLY A 113ALA A 114 | None | 0.69A | 5f1aA-6g21A:undetectable | 5f1aA-6g21A:10.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbg | OUTER MEMBRANEPROTEIN (Helicobacterpylori) |
no annotation | 4 | VAL A 101LEU A 241LEU A 355TRP A 260 | None | 0.73A | 5f1aA-6gbgA:undetectable | 5f1aA-6gbgA:8.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbh | HOPQ (Helicobacterpylori) |
no annotation | 4 | VAL C 105LEU C 241LEU C 352TRP C 259 | None | 0.74A | 5f1aA-6gbhC:undetectable | 5f1aA-6gbhC:9.65 |