SIMILAR PATTERNS OF AMINO ACIDS FOR 5F1A_A_SALA601

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a87 COLICIN N

(Escherichia
coli)
PF01024
(Colicin)
4 LEU A 366
GLY A 339
ALA A 340
SER A 343
None
0.57A 5f1aA-1a87A:
0.0
5f1aA-1a87A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhd UTROPHIN

(Homo sapiens)
PF00307
(CH)
4 VAL A 253
LEU A 254
LEU A 196
ALA A 218
None
0.75A 5f1aA-1bhdA:
undetectable
5f1aA-1bhdA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxk PROTEIN
(DTDP-GLUCOSE
4,6-DEHYDRATASE)


(Escherichia
coli)
PF16363
(GDP_Man_Dehyd)
4 LEU A 287
TYR A 284
GLY A 211
ALA A 210
None
0.77A 5f1aA-1bxkA:
undetectable
5f1aA-1bxkA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cg2 CARBOXYPEPTIDASE G2

(Pseudomonas sp.
RS-16)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
4 LEU A 107
TYR A 195
GLY A 412
ALA A 413
None
0.65A 5f1aA-1cg2A:
undetectable
5f1aA-1cg2A:
22.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE


(Ovis aries)
PF00008
(EGF)
PF03098
(An_peroxidase)
6 VAL A 349
LEU A 352
LEU A 384
TYR A 385
TRP A 387
GLY A 526
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
None
None
SCL  A 700 ( 4.0A)
0.63A 5f1aA-1ebvA:
58.7
5f1aA-1ebvA:
63.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE


(Ovis aries)
PF00008
(EGF)
PF03098
(An_peroxidase)
6 VAL A 349
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
SCL  A 700 ( 4.6A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
0.35A 5f1aA-1ebvA:
58.7
5f1aA-1ebvA:
63.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htt HISTIDYL-TRNA
SYNTHETASE


(Escherichia
coli)
PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His)
4 LEU A  43
TYR A 107
GLY A  87
ALA A  86
None
0.65A 5f1aA-1httA:
0.0
5f1aA-1httA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN


(Mus musculus)
PF02816
(Alpha_kinase)
4 LEU A1706
GLY A1712
ALA A1711
SER A1710
None
0.78A 5f1aA-1iahA:
0.0
5f1aA-1iahA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2b ARCHAEOSINE
TRNA-GUANINE
TRANSGLYCOSYLASE


(Pyrococcus
horikoshii)
PF01472
(PUA)
PF01702
(TGT)
PF14809
(TGT_C1)
PF14810
(TGT_C2)
4 LEU A 349
LEU A 328
TRP A 329
ALA A 240
None
0.81A 5f1aA-1j2bA:
0.0
5f1aA-1j2bA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jct GLUCARATE
DEHYDRATASE


(Escherichia
coli)
PF13378
(MR_MLE_C)
4 VAL A 132
LEU A 136
LEU A  84
ALA A 118
None
0.79A 5f1aA-1jctA:
0.0
5f1aA-1jctA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)


(Paracoccus
denitrificans)
PF06433
(Me-amine-dh_H)
4 VAL H  98
LEU H 161
GLY H 150
SER H 152
None
0.80A 5f1aA-1mdaH:
0.0
5f1aA-1mdaH:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4t EXOENZYME S

(Pseudomonas
aeruginosa)
PF03545
(YopE)
4 VAL A 195
LEU A 202
GLY A 130
ALA A 132
None
0.73A 5f1aA-1r4tA:
undetectable
5f1aA-1r4tA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlt PUTATIVE
OXIDOREDUCTASE
(VIRULENCE FACTOR
MVIM HOMOLOG)


(Escherichia
coli)
PF01408
(GFO_IDH_MocA)
4 VAL A  81
LEU A  59
GLY A  12
SER A  73
None
0.74A 5f1aA-1tltA:
undetectable
5f1aA-1tltA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6z EXOPOLYPHOSPHATASE

(Escherichia
coli)
PF02541
(Ppx-GppA)
4 LEU A 290
GLY A 215
ALA A 216
SER A 293
None
0.82A 5f1aA-1u6zA:
undetectable
5f1aA-1u6zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vey PEPTIDE DEFORMYLASE

(Leptospira
interrogans)
PF01327
(Pep_deformylase)
4 VAL A 154
LEU A 157
LEU A 169
GLY A 164
None
0.83A 5f1aA-1veyA:
undetectable
5f1aA-1veyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xov PLY PROTEIN

(Listeria virus
PSA)
PF01520
(Amidase_3)
4 LEU A  21
LEU A 163
TYR A 160
ALA A 153
None
0.81A 5f1aA-1xovA:
undetectable
5f1aA-1xovA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3v CELLULASE

(Phanerochaete
chrysosporium)
PF00840
(Glyco_hydro_7)
4 LEU A 374
LEU A 133
GLY A 139
ALA A 140
None
0.76A 5f1aA-1z3vA:
undetectable
5f1aA-1z3vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z72 TRANSCRIPTIONAL
REGULATOR, PUTATIVE


(Streptococcus
pneumoniae)
PF03070
(TENA_THI-4)
4 LEU A 142
LEU A  85
GLY A  66
ALA A  67
None
0.81A 5f1aA-1z72A:
0.4
5f1aA-1z72A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2col BIFUNCTIONAL
HEMOLYSIN-ADENYLATE
CYCLASE


(Bordetella
pertussis)
PF03497
(Anthrax_toxA)
4 LEU A 113
GLY A  74
ALA A  73
SER A  67
None
0.83A 5f1aA-2colA:
undetectable
5f1aA-2colA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2elc ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE


(Thermus
thermophilus)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
4 VAL A 215
LEU A  74
GLY A 290
ALA A 289
None
0.73A 5f1aA-2elcA:
undetectable
5f1aA-2elcA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g28 PYRUVATE
DEHYDROGENASE E1
COMPONENT


(Escherichia
coli)
PF00456
(Transketolase_N)
4 LEU A 610
GLY A 575
ALA A 574
SER A 577
None
0.82A 5f1aA-2g28A:
undetectable
5f1aA-2g28A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j89 METHIONINE SULFOXIDE
REDUCTASE A


(Populus
trichocarpa)
PF01625
(PMSR)
4 LEU A 180
TYR A 179
TRP A  48
GLY A 204
None
None
BME  A 207 ( 4.2A)
None
0.76A 5f1aA-2j89A:
undetectable
5f1aA-2j89A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN


(Thermus
thermophilus)
PF14589
(NrfD_2)
4 LEU C 176
LEU C 184
GLY C 217
ALA C 230
None
0.73A 5f1aA-2vpwC:
undetectable
5f1aA-2vpwC:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE


(Xanthomonas
campestris)
PF00128
(Alpha-amylase)
PF11941
(DUF3459)
4 LEU A 478
GLY A 357
ALA A 356
SER A 359
None
0.80A 5f1aA-2wpgA:
undetectable
5f1aA-2wpgA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wua ACETOACETYL COA
THIOLASE


(Helianthus
annuus)
PF00108
(Thiolase_N)
PF02803
(Thiolase_C)
5 VAL A 277
LEU A 271
GLY A 287
ALA A 286
SER A 289
None
1.18A 5f1aA-2wuaA:
undetectable
5f1aA-2wuaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycj 5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE


(Carboxydothermus
hydrogenoformans)
PF00809
(Pterin_bind)
4 LEU A 163
LEU A 144
GLY A 122
SER A  98
None
0.83A 5f1aA-2ycjA:
undetectable
5f1aA-2ycjA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)


(Thermus
thermophilus)
PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
4 LEU A 202
GLY A 255
ALA A 254
SER A 251
None
0.75A 5f1aA-3auoA:
undetectable
5f1aA-3auoA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cze SUCROSE HYDROLASE

(Xanthomonas
citri)
PF00128
(Alpha-amylase)
4 LEU A 477
GLY A 356
ALA A 355
SER A 358
None
0.77A 5f1aA-3czeA:
undetectable
5f1aA-3czeA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gi8 UNCHARACTERIZED
PROTEIN MJ0609


(Methanocaldococcus
jannaschii)
PF13520
(AA_permease_2)
4 LEU C 162
GLY C 279
ALA C 280
SER C 283
None
0.72A 5f1aA-3gi8C:
undetectable
5f1aA-3gi8C:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gmt ADENYLATE KINASE

(Burkholderia
pseudomallei)
PF00406
(ADK)
PF05191
(ADK_lid)
5 VAL A  68
LEU A  72
LEU A 194
GLY A 100
ALA A  99
None
1.24A 5f1aA-3gmtA:
undetectable
5f1aA-3gmtA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hlm ASPARTATE
AMINOTRANSFERASE,
MITOCHONDRIAL


(Mus musculus)
PF00155
(Aminotran_1_2)
4 VAL A 129
TYR A 316
GLY A 136
ALA A 137
None
0.68A 5f1aA-3hlmA:
undetectable
5f1aA-3hlmA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7y MS30

(Homo sapiens)
PF00829
(Ribosomal_L21p)
4 LEU s  80
LEU s 377
GLY s 337
ALA s 338
None
0.66A 5f1aA-3j7ys:
undetectable
5f1aA-3j7ys:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb5 MAJOR CAPSID PROTEIN

(Propionibacterium
virus PA6)
no annotation 4 LEU A 122
GLY A 229
ALA A 230
SER A 225
None
0.80A 5f1aA-3jb5A:
undetectable
5f1aA-3jb5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jui TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT
EPSILON


(Homo sapiens)
PF02020
(W2)
4 LEU A 646
LEU A 710
GLY A 678
ALA A 677
None
0.58A 5f1aA-3juiA:
2.0
5f1aA-3juiA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldz SIGNAL TRANSDUCING
ADAPTER MOLECULE 1


(Homo sapiens)
PF00790
(VHS)
4 LEU A 111
GLY A  70
ALA A  71
SER A  74
None
0.65A 5f1aA-3ldzA:
undetectable
5f1aA-3ldzA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nxl GLUCARATE
DEHYDRATASE


(Burkholderia
lata)
PF13378
(MR_MLE_C)
4 VAL A 152
LEU A 156
LEU A  88
ALA A 138
None
0.76A 5f1aA-3nxlA:
undetectable
5f1aA-3nxlA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oc4 OXIDOREDUCTASE,
PYRIDINE
NUCLEOTIDE-DISULFIDE
FAMILY


(Enterococcus
faecalis)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 LEU A  30
GLY A  12
ALA A  11
SER A  14
None
None
FAD  A 500 (-3.3A)
None
0.76A 5f1aA-3oc4A:
undetectable
5f1aA-3oc4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE


(Streptococcus
pyogenes)
PF01321
(Creatinase_N)
4 VAL A  83
LEU A  87
LEU A  21
GLY A  96
None
0.58A 5f1aA-3ovkA:
undetectable
5f1aA-3ovkA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN


(Ralstonia
pickettii)
PF13378
(MR_MLE_C)
4 VAL A 148
LEU A 152
LEU A  84
ALA A 134
None
0.77A 5f1aA-3p0wA:
undetectable
5f1aA-3p0wA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r8x METHIONYL-TRNA
FORMYLTRANSFERASE


(Yersinia pestis)
PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C)
4 LEU A  55
GLY A  21
ALA A  22
SER A  25
None
0.65A 5f1aA-3r8xA:
undetectable
5f1aA-3r8xA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rza TRIPEPTIDASE

(Staphylococcus
aureus)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
4 VAL A 138
LEU A  53
GLY A 149
ALA A 150
None
0.60A 5f1aA-3rzaA:
undetectable
5f1aA-3rzaA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swg UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Aquifex
aeolicus)
PF00275
(EPSP_synthase)
4 LEU A 273
LEU A 384
GLY A 248
ALA A 249
None
0.83A 5f1aA-3swgA:
undetectable
5f1aA-3swgA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t33 G PROTEIN COUPLED
RECEPTOR


(Arabidopsis
thaliana)
PF05147
(LANC_like)
4 LEU A  80
TYR A  73
GLY A 127
ALA A 126
None
0.71A 5f1aA-3t33A:
undetectable
5f1aA-3t33A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT


(Campylobacter
jejuni)
PF02091
(tRNA-synt_2e)
4 VAL A 145
LEU A 283
GLY A  44
SER A  42
None
0.66A 5f1aA-3ufgA:
undetectable
5f1aA-3ufgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v94 CYCLIC NUCLEOTIDE
SPECIFIC
PHOSPHODIESTERASE


(Trypanosoma
cruzi)
PF00233
(PDEase_I)
4 LEU A 584
GLY A 493
ALA A 494
SER A 497
None
0.62A 5f1aA-3v94A:
undetectable
5f1aA-3v94A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0y DSZC

(Rhodococcus
erythropolis)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2)
4 LEU A  93
GLY A 164
ALA A 165
SER A 168
None
0.81A 5f1aA-3x0yA:
0.0
5f1aA-3x0yA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a9w MONOOXYGENASE

(Stenotrophomonas
maltophilia)
PF13738
(Pyr_redox_3)
5 VAL A 336
LEU A  91
TYR A  85
GLY A  19
ALA A  18
None
1.16A 5f1aA-4a9wA:
undetectable
5f1aA-4a9wA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3n MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5


(Escherichia
coli;
Macaca mulatta)
PF00622
(SPRY)
PF01547
(SBP_bac_1)
4 LEU A  76
GLY A 265
ALA A 264
SER A 263
None
0.83A 5f1aA-4b3nA:
undetectable
5f1aA-4b3nA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB


(Pyrococcus
horikoshii)
PF01139
(RtcB)
4 VAL A 147
LEU A 148
GLY A 191
ALA A 192
None
0.72A 5f1aA-4dwqA:
undetectable
5f1aA-4dwqA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxb MALTOSE-BINDING
PERIPLASMIC PROTEIN,
BETA-LACTAMASE TEM
CHIMERA


(Escherichia
coli)
PF01547
(SBP_bac_1)
PF13354
(Beta-lactamase2)
4 LEU A  76
GLY A 265
ALA A 264
SER A 263
None
0.83A 5f1aA-4dxbA:
undetectable
5f1aA-4dxbA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hn8 D-GLUCARATE
DEHYDRATASE


(Pseudomonas
mendocina)
PF13378
(MR_MLE_C)
4 VAL A 149
LEU A 153
LEU A  86
ALA A 135
None
0.77A 5f1aA-4hn8A:
undetectable
5f1aA-4hn8A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hqb SINGLE-STRANDED
DNA-BINDING PROTEIN
DDRB


(Deinococcus
radiodurans)
PF12747
(DdrB)
4 VAL A 115
TYR A  82
GLY A 106
ALA A 107
None
0.73A 5f1aA-4hqbA:
undetectable
5f1aA-4hqbA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inz SOLUBLE EPOXIDE
HYDROLASE


(Bacillus
megaterium)
PF00561
(Abhydrolase_1)
4 LEU A  93
LEU A  55
GLY A  99
ALA A 100
None
0.71A 5f1aA-4inzA:
undetectable
5f1aA-4inzA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j57 THIOREDOXIN
REDUCTASE 2


(Plasmodium
falciparum)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 VAL A  73
LEU A  69
TYR A 156
GLY A  49
FAD  A 601 (-3.5A)
None
None
FAD  A 601 ( 4.8A)
0.75A 5f1aA-4j57A:
1.3
5f1aA-4j57A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxu PUTATIVE
AMINOTRANSFERASE


(Sinorhizobium
meliloti)
PF01063
(Aminotran_4)
4 LEU A 139
LEU A 169
GLY A 193
SER A 195
None
0.67A 5f1aA-4jxuA:
undetectable
5f1aA-4jxuA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4om9 SERINE PROTEASE PET

(Escherichia
coli)
PF02395
(Peptidase_S6)
4 LEU A 171
GLY A  57
ALA A  58
SER A 210
None
0.72A 5f1aA-4om9A:
undetectable
5f1aA-4om9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqy (S)-IMINE REDUCTASE

(Streptomyces
sp. GF3546)
PF03446
(NAD_binding_2)
4 LEU A 285
LEU A 234
GLY A 268
ALA A 267
None
0.81A 5f1aA-4oqyA:
undetectable
5f1aA-4oqyA:
18.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2


(Mus musculus)
PF00008
(EGF)
PF03098
(An_peroxidase)
5 LEU A 353
LEU A 385
TYR A 386
TRP A 388
GLY A 527
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
0.69A 5f1aA-4ph9A:
63.4
5f1aA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2


(Mus musculus)
PF00008
(EGF)
PF03098
(An_peroxidase)
6 VAL A 350
LEU A 385
TYR A 386
TRP A 388
GLY A 527
ALA A 528
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
0.20A 5f1aA-4ph9A:
63.4
5f1aA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2


(Mus musculus)
PF00008
(EGF)
PF03098
(An_peroxidase)
4 VAL A 350
TYR A 386
ALA A 528
SER A 531
IBP  A 601 (-4.3A)
IBP  A 601 (-4.8A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
0.74A 5f1aA-4ph9A:
63.4
5f1aA-4ph9A:
88.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjy GH127
BETA-L-ARABINOFURANO
SIDASE


(Geobacillus
stearothermophilus)
PF07944
(Glyco_hydro_127)
4 LEU A 358
LEU A  12
GLY A 419
SER A 417
None
None
None
ACT  A 703 ( 4.0A)
0.80A 5f1aA-4qjyA:
undetectable
5f1aA-4qjyA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkc AROMATIC AMINO ACID
AMINOTRANSFERASE


(Psychrobacter
sp. B6)
PF00155
(Aminotran_1_2)
4 VAL A 174
LEU A 258
GLY A 110
ALA A 111
None
0.80A 5f1aA-4rkcA:
undetectable
5f1aA-4rkcA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE LARGE
SUBUNIT


(Desulfovibrio
vulgaris)
PF00374
(NiFeSe_Hases)
4 VAL L 415
LEU L 410
LEU L 388
GLY L 425
None
0.82A 5f1aA-4u9iL:
undetectable
5f1aA-4u9iL:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubt ACETYL-COA
ACETYLTRANSFERASE
FADA5


(Mycobacterium
tuberculosis)
PF00108
(Thiolase_N)
PF02803
(Thiolase_C)
5 VAL A 234
LEU A 228
GLY A 243
ALA A 242
SER A 245
None
None
COA  A 401 ( 4.3A)
COA  A 401 (-3.5A)
COA  A 401 ( 4.0A)
0.99A 5f1aA-4ubtA:
undetectable
5f1aA-4ubtA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upe NICKEL-DEPENDENT
HYDROGENASE LARGE
SUBUNIT


(Desulfovibrio
fructosivorans)
PF00374
(NiFeSe_Hases)
4 VAL Q 413
LEU Q 408
LEU Q 386
GLY Q 423
None
0.82A 5f1aA-4upeQ:
undetectable
5f1aA-4upeQ:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wb0 BROAD SPECIFICITY
AMINOTRANSFERASE


(Leishmania
mexicana)
PF00155
(Aminotran_1_2)
4 VAL A 105
TYR A 294
GLY A 112
ALA A 113
None
CSO  A 296 ( 4.6A)
None
None
0.73A 5f1aA-4wb0A:
undetectable
5f1aA-4wb0A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wb0 BROAD SPECIFICITY
AMINOTRANSFERASE


(Leishmania
mexicana)
PF00155
(Aminotran_1_2)
4 VAL A 184
LEU A 269
GLY A 117
ALA A 118
None
0.66A 5f1aA-4wb0A:
undetectable
5f1aA-4wb0A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB


(Brucella
abortus)
PF00294
(PfkB)
4 LEU A  65
LEU A   3
ALA A  75
SER A  50
None
0.79A 5f1aA-4wjmA:
undetectable
5f1aA-4wjmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxt THIOREDOXIN

(Mycobacterium
avium)
PF00085
(Thioredoxin)
4 VAL A  47
LEU A  48
GLY A  98
ALA A  99
None
0.82A 5f1aA-4wxtA:
undetectable
5f1aA-4wxtA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xsr ALR3699 PROTEIN

(Nostoc sp. PCC
7120)
no annotation 4 LEU B   6
GLY B 105
ALA B 106
SER B 109
None
0.66A 5f1aA-4xsrB:
undetectable
5f1aA-4xsrB:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ymw ABC-TYPE AMINO ACID
TRANSPORT SYSTEM,
PERMEASE COMPONENT


(Caldanaerobacter
subterraneus)
no annotation 4 LEU D  25
GLY D  91
ALA D  90
SER D  93
None
0.76A 5f1aA-4ymwD:
undetectable
5f1aA-4ymwD:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a12 CHLORITE DISMUTASE

(Magnetospirillum
sp.)
PF06778
(Chlor_dismutase)
4 LEU A 175
GLY A 130
ALA A 129
SER A 132
HEM  A 250 ( 4.7A)
None
None
None
0.81A 5f1aA-5a12A:
undetectable
5f1aA-5a12A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1


(Homo sapiens)
PF12859
(ANAPC1)
4 LEU A1405
GLY A1467
ALA A1468
SER A1471
None
0.79A 5f1aA-5a31A:
undetectable
5f1aA-5a31A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxp LACTO-N-BIOSIDASE

(Bifidobacterium
bifidum)
PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF14200
(RicinB_lectin_2)
4 LEU A 370
GLY A 318
ALA A 319
SER A 260
None
0.80A 5f1aA-5bxpA:
undetectable
5f1aA-5bxpA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE


(Pseudomonas
aeruginosa)
PF01575
(MaoC_dehydratas)
4 LEU A  88
GLY A  65
ALA A  66
SER A  69
None
0.54A 5f1aA-5cpgA:
undetectable
5f1aA-5cpgA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csc CITRATE SYNTHASE

(Gallus gallus)
PF00285
(Citrate_synt)
5 VAL B 350
LEU B 353
TRP B 284
GLY B 317
ALA B 376
None
1.40A 5f1aA-5cscB:
undetectable
5f1aA-5cscB:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3i HISTIDINE--TRNA
LIGASE


(Acinetobacter
baumannii)
PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His)
4 LEU A  43
TYR A 109
GLY A  89
ALA A  88
None
0.73A 5f1aA-5e3iA:
undetectable
5f1aA-5e3iA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ez3 ACYL-COA
DEHYDROGENASE


(Brucella
melitensis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
4 VAL A 390
LEU A 507
GLY A 358
ALA A 359
None
0.82A 5f1aA-5ez3A:
0.1
5f1aA-5ez3A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g3y ADENYLATE KINSE

(synthetic
construct)
PF00406
(ADK)
PF05191
(ADK_lid)
4 VAL A  63
LEU A  67
GLY A  46
ALA A  49
None
0.82A 5f1aA-5g3yA:
undetectable
5f1aA-5g3yA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7t CLASS IV CHITINASE

(Cryptomeria
japonica)
no annotation 4 LEU A 124
GLY A 113
ALA A 114
SER A 117
None
0.63A 5f1aA-5h7tA:
undetectable
5f1aA-5h7tA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hes MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 LEU A  47
LEU A  57
GLY A 153
ALA A 154
None
032  A 401 ( 4.7A)
032  A 401 (-3.6A)
None
0.78A 5f1aA-5hesA:
undetectable
5f1aA-5hesA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hft GAMMA-GLUTAMYLTRANSP
EPTIDASE


(Klebsiella
pneumoniae)
PF01019
(G_glu_transpept)
4 LEU A 251
GLY A  58
ALA A  74
SER A  75
None
0.80A 5f1aA-5hftA:
undetectable
5f1aA-5hftA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i7n MAOC-LIKE
DEHYDRATASE


(Mycobacteroides
abscessus)
PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N)
4 VAL A 339
LEU A  54
GLY A 203
SER A 275
None
0.79A 5f1aA-5i7nA:
undetectable
5f1aA-5i7nA:
21.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2


(Homo sapiens)
PF00008
(EGF)
PF03098
(An_peroxidase)
8 VAL A 349
LEU A 352
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
SER A 530
ID8  A 601 (-3.9A)
ID8  A 601 (-4.1A)
ID8  A 601 ( 4.8A)
ID8  A 601 ( 3.5A)
COH  A 602 (-4.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
0.36A 5f1aA-5ikrA:
63.7
5f1aA-5ikrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5in8 ARISTOLOCHENE
SYNTHASE


(Aspergillus
terreus)
no annotation 4 VAL A 272
LEU A 275
LEU A 190
ALA A 286
None
0.72A 5f1aA-5in8A:
undetectable
5f1aA-5in8A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3x NEGATIVE ELONGATION
FACTOR C/D


(Homo sapiens)
PF04858
(TH1)
4 LEU B 281
GLY B 297
ALA B 298
SER B 301
None
0.52A 5f1aA-5l3xB:
1.6
5f1aA-5l3xB:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1


(Homo sapiens)
PF12859
(ANAPC1)
4 LEU A1405
GLY A1467
ALA A1468
SER A1471
None
0.80A 5f1aA-5lcwA:
undetectable
5f1aA-5lcwA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mkk MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN


(Thermus
thermophilus)
PF00005
(ABC_tran)
PF00664
(ABC_membrane)
4 LEU B 165
LEU B 278
GLY B 264
ALA B 263
None
0.60A 5f1aA-5mkkB:
undetectable
5f1aA-5mkkB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nsq AMINOPEPTIDASE,
PUTATIVE


(Trypanosoma
brucei)
PF00883
(Peptidase_M17)
4 LEU A 378
LEU A 496
GLY A 315
ALA A 316
None
0.56A 5f1aA-5nsqA:
undetectable
5f1aA-5nsqA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swn FLUOROACETATE
DEHALOGENASE


(Rhodopseudomonas
palustris)
PF00561
(Abhydrolase_1)
4 LEU A 106
LEU A  65
GLY A 112
ALA A 113
None
0.58A 5f1aA-5swnA:
undetectable
5f1aA-5swnA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u03 CTP SYNTHASE 1

(Homo sapiens)
PF00117
(GATase)
PF06418
(CTP_synth_N)
4 VAL A   6
LEU A  78
TYR A  74
GLY A  24
None
0.71A 5f1aA-5u03A:
undetectable
5f1aA-5u03A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE


(Echinococcus
granulosus)
no annotation 4 VAL A 141
LEU A 137
TYR A 223
GLY A 117
FAD  A 601 ( 3.8A)
None
None
FAD  A 601 (-4.4A)
0.66A 5f1aA-5w1jA:
undetectable
5f1aA-5w1jA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmd EPOXIDE HYDROLASE A

(Vigna radiata)
no annotation 4 LEU A  97
LEU A  59
GLY A 103
ALA A 104
None
0.66A 5f1aA-5xmdA:
undetectable
5f1aA-5xmdA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnw ADENYLATE CYCLASE
EXOY


(Pseudomonas
aeruginosa)
no annotation 4 LEU A 137
GLY A  97
ALA A  96
SER A  90
None
0.72A 5f1aA-5xnwA:
undetectable
5f1aA-5xnwA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byn WD REPEAT-CONTAINING
PROTEIN 5


(Homo sapiens)
no annotation 4 LEU W 249
LEU W 209
GLY W 246
SER W 244
None
0.72A 5f1aA-6bynW:
undetectable
5f1aA-6bynW:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
ATP SYNTHASE GAMMA
SUBUNIT
ATP SYNTHASE SUBUNIT
BETA


(Trypanosoma
brucei)
no annotation 4 LEU A 297
LEU G 284
GLY D 278
SER D 274
None
0.81A 5f1aA-6f5dA:
undetectable
5f1aA-6f5dA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fm9 UDP-N-ACETYLGLUCOSAM
INE--DOLICHYL-PHOSPH
ATE
N-ACETYLGLUCOSAMINEP
HOSPHOTRANSFERASE


(Homo sapiens)
no annotation 4 LEU A 384
GLY A 196
ALA A 195
SER A 198
None
0.83A 5f1aA-6fm9A:
undetectable
5f1aA-6fm9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g21 PROBABLE FERULOYL
ESTERASE B-2


(Aspergillus
oryzae)
no annotation 4 LEU A 101
TYR A  98
GLY A 113
ALA A 114
None
0.69A 5f1aA-6g21A:
undetectable
5f1aA-6g21A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbg OUTER MEMBRANE
PROTEIN


(Helicobacter
pylori)
no annotation 4 VAL A 101
LEU A 241
LEU A 355
TRP A 260
None
0.73A 5f1aA-6gbgA:
undetectable
5f1aA-6gbgA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbh HOPQ

(Helicobacter
pylori)
no annotation 4 VAL C 105
LEU C 241
LEU C 352
TRP C 259
None
0.74A 5f1aA-6gbhC:
undetectable
5f1aA-6gbhC:
9.65