SIMILAR PATTERNS OF AMINO ACIDS FOR 5ESM_A_TPFA602_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica)
PF00072
(Response_reg)
PF01339
(CheB_methylest)
4 PHE A 199
GLY A 167
THR A 281
LEU A 330
None
0.84A 5esmA-1a2oA:
0.0
5esmA-1a2oA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT


(Escherichia
coli)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3)
4 PHE A 928
GLY A1046
THR A1043
LEU A 907
None
None
ORN  A4010 ( 4.9A)
ORN  A4010 (-4.0A)
0.92A 5esmA-1c30A:
0.0
5esmA-1c30A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chd CHEB METHYLESTERASE

(Salmonella
enterica)
PF01339
(CheB_methylest)
4 PHE A 199
GLY A 167
THR A 281
LEU A 330
None
0.83A 5esmA-1chdA:
undetectable
5esmA-1chdA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnz BARK AGGLUTININ I,
POLYPEPTIDE A


(Robinia
pseudoacacia)
PF00139
(Lectin_legB)
4 TYR A 170
PHE A 231
PHE A  56
LEU A 202
None
1.03A 5esmA-1fnzA:
undetectable
5esmA-1fnzA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0q SURFACE LAYER
PROTEIN


(Methanosarcina
mazei)
PF00801
(PKD)
PF10282
(Lactonase)
4 PHE A 294
ILE A   6
GLY A 248
THR A 217
None
0.93A 5esmA-1l0qA:
undetectable
5esmA-1l0qA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llc L-LACTATE
DEHYDROGENASE


(Lactobacillus
casei)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ILE A 281
PHE A 200
GLY A 193
THR A 165
None
0.99A 5esmA-1llcA:
1.8
5esmA-1llcA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pww LETHAL FACTOR

(Bacillus
anthracis)
PF07737
(ATLF)
PF09156
(Anthrax-tox_M)
4 PHE A 631
ILE A 602
THR A 619
LEU A 574
None
1.03A 5esmA-1pwwA:
0.3
5esmA-1pwwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens)
PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N)
4 TYR A 406
GLY A 492
THR A 496
LEU A 457
None
1.02A 5esmA-1rw9A:
undetectable
5esmA-1rw9A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tuo PUTATIVE
PHOSPHOMANNOMUTASE


(Thermus
thermophilus)
PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III)
4 PHE A  14
ILE A  12
PHE A 120
LEU A  68
None
1.02A 5esmA-1tuoA:
0.0
5esmA-1tuoA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhk HYPOTHETICAL PROTEIN
YQEU


(Bacillus
subtilis)
PF04452
(Methyltrans_RNA)
4 ILE A  83
PHE A 111
GLY A 204
LEU A 217
None
1.02A 5esmA-1vhkA:
undetectable
5esmA-1vhkA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wky ENDO-BETA-1,4-MANNAN
ASE


(Bacillus sp.
JAMB-602)
PF00150
(Cellulase)
4 TYR A 271
ILE A 268
GLY A 278
LEU A 243
None
None
None
CL  A 501 (-4.3A)
0.92A 5esmA-1wkyA:
undetectable
5esmA-1wkyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wom SIGMA FACTOR SIGB
REGULATION PROTEIN
RSBQ


(Bacillus
subtilis)
PF12697
(Abhydrolase_6)
4 PHE A  41
ILE A  21
GLY A 262
LEU A 214
None
0.86A 5esmA-1womA:
undetectable
5esmA-1womA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wr8 PHOSPHOGLYCOLATE
PHOSPHATASE


(Pyrococcus
horikoshii)
PF08282
(Hydrolase_3)
4 TYR A 207
PHE A 185
GLY A 176
THR A  13
None
1.02A 5esmA-1wr8A:
undetectable
5esmA-1wr8A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x8v CYTOCHROME P450 51

(Mycobacterium
tuberculosis)
PF00067
(p450)
4 TYR A  76
PHE A  83
THR A 260
LEU A 321
ESL  A 471 ( 3.8A)
None
HEM  A 470 (-3.6A)
HEM  A 470 (-4.1A)
0.90A 5esmA-1x8vA:
35.2
5esmA-1x8vA:
28.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buy PROTOCATECHUATE
3,4-DIOXYGENASE
ALPHA CHAIN


(Acinetobacter
sp. ADP1)
PF00775
(Dioxygenase_C)
4 ILE A 129
PHE A 106
GLY A  93
LEU A  22
None
1.01A 5esmA-2buyA:
undetectable
5esmA-2buyA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0k HEMOGLOBIN

(Gasterophilus
intestinalis)
PF00042
(Globin)
4 TYR A 140
ILE A 142
PHE A 135
GLY A  73
None
0.94A 5esmA-2c0kA:
undetectable
5esmA-2c0kA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dt9 ASPARTOKINASE

(Thermus
thermophilus)
PF01842
(ACT)
PF13840
(ACT_7)
4 ILE A  24
PHE A  64
GLY A  20
LEU A  75
None
0.99A 5esmA-2dt9A:
undetectable
5esmA-2dt9A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE


(Streptococcus
gordonii)
PF00728
(Glyco_hydro_20)
4 ILE X 618
GLY X 342
THR X 344
LEU X 495
None
0.86A 5esmA-2epkX:
undetectable
5esmA-2epkX:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7r CXE CARBOXYLESTERASE

(Actinidia
eriantha)
PF07859
(Abhydrolase_3)
4 PHE A 104
ILE A 103
GLY A  92
LEU A 222
None
None
4PA  A 369 (-3.5A)
None
0.69A 5esmA-2o7rA:
undetectable
5esmA-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozj CUPIN 2, CONSERVED
BARREL


(Desulfitobacterium
hafniense)
no annotation 4 TYR A  61
ILE A  63
PHE A  44
GLY A  97
None
0.93A 5esmA-2ozjA:
undetectable
5esmA-2ozjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2reb REC A

(Escherichia
coli)
PF00154
(RecA)
4 TYR A  65
ILE A 192
GLY A  71
THR A 242
None
0.82A 5esmA-2rebA:
undetectable
5esmA-2rebA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfo NUCLEOPORIN NIC96

(Saccharomyces
cerevisiae)
PF04097
(Nic96)
4 TYR A 556
PHE A 534
ILE A 537
GLY A 509
None
0.75A 5esmA-2rfoA:
undetectable
5esmA-2rfoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vda TRANSLOCASE SUBUNIT
SECA


(Escherichia
coli)
PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD)
4 PHE A  68
ILE A  64
GLY A  91
LEU A 207
None
1.00A 5esmA-2vdaA:
undetectable
5esmA-2vdaA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpi GMP SYNTHASE

(Homo sapiens)
PF00117
(GATase)
4 PHE A 140
ILE A 202
GLY A 176
LEU A 151
None
1.03A 5esmA-2vpiA:
undetectable
5esmA-2vpiA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wed PENICILLOPEPSIN

(Penicillium
janthinellum)
PF00026
(Asp)
4 ILE A 260
PHE A 208
GLY A 210
LEU A 219
None
0.90A 5esmA-2wedA:
undetectable
5esmA-2wedA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wlc POLYSIALIC ACID
O-ACETYLTRANSFERASE


(Neisseria
meningitidis)
PF00132
(Hexapep)
4 ILE A 139
GLY A 104
THR A  86
LEU A 109
None
EDO  A1218 (-3.5A)
None
None
0.80A 5esmA-2wlcA:
undetectable
5esmA-2wlcA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwu IMPORTIN13

(Homo sapiens)
PF03810
(IBN_N)
PF08389
(Xpo1)
4 ILE B  84
PHE B  61
GLY B  78
LEU B  30
None
0.99A 5esmA-2xwuB:
undetectable
5esmA-2xwuB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zah COAT PROTEIN

(Melon necrotic
spot virus)
PF00729
(Viral_coat)
4 ILE A 288
PHE A 364
GLY A 301
LEU A 316
None
1.00A 5esmA-2zahA:
undetectable
5esmA-2zahA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9g PUTATIVE
UNCHARACTERIZED
PROTEIN


(Pyrobaculum
aerophilum)
PF07995
(GSDH)
4 ILE A 344
GLY A 280
THR A 231
LEU A 296
None
0.94A 5esmA-3a9gA:
undetectable
5esmA-3a9gA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ccy PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR


(Bordetella
parapertussis)
PF00440
(TetR_N)
4 TYR A 134
PHE A 161
ILE A 132
PHE A  95
None
0.99A 5esmA-3ccyA:
undetectable
5esmA-3ccyA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cji POLYPROTEIN

(Senecavirus A)
PF00073
(Rhv)
4 PHE B 131
PHE B 121
GLY B 129
LEU B 204
None
1.01A 5esmA-3cjiB:
undetectable
5esmA-3cjiB:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A1065
ILE A1192
GLY A1071
THR A1242
None
None
ANP  A1400 (-3.1A)
None
0.84A 5esmA-3cmvA:
undetectable
5esmA-3cmvA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8b FIDGETIN-LIKE
PROTEIN 1


(Homo sapiens)
PF00004
(AAA)
PF09336
(Vps4_C)
4 PHE A 486
ILE A 539
PHE A 524
LEU A 559
None
0.86A 5esmA-3d8bA:
undetectable
5esmA-3d8bA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmb DIMERIC PROTEIN OF
UNKNOWN FUNCTION AND
FERREDOXIN-LIKE FOLD


(Bacteroides
fragilis)
PF07876
(Dabb)
4 PHE A   8
ILE A  57
GLY A  82
LEU A  33
None
0.65A 5esmA-3fmbA:
undetectable
5esmA-3fmbA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goc ENDONUCLEASE V

(Streptomyces
avermitilis)
PF04493
(Endonuclease_5)
4 PHE A 124
GLY A 131
THR A 134
LEU A  98
None
1.02A 5esmA-3gocA:
undetectable
5esmA-3gocA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE
FAD-SUBUNIT


(Eubacterium
barkeri)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
4 PHE C  77
ILE C  80
GLY C 112
LEU C 148
FAD  C 900 (-4.2A)
None
FAD  C 900 ( 4.3A)
None
0.87A 5esmA-3hrdC:
undetectable
5esmA-3hrdC:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 1


(Thermus
thermophilus)
PF01512
(Complex1_51K)
PF10531
(SLBB)
PF10589
(NADH_4Fe-4S)
4 ILE 1 149
PHE 1 169
GLY 1 130
LEU 1 224
None
0.94A 5esmA-3i9v1:
undetectable
5esmA-3i9v1:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iz3 VIRAL STRUCTURAL
PROTEIN 5


(Cypovirus 1)
no annotation 4 PHE D  31
ILE D  19
PHE D 179
THR D 233
None
0.87A 5esmA-3iz3D:
undetectable
5esmA-3iz3D:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7a 40S RIBOSOMAL
PROTEIN US19


(Plasmodium
falciparum)
PF00203
(Ribosomal_S19)
4 PHE X  37
ILE X 112
PHE X  45
LEU X  57
None
0.95A 5esmA-3j7aX:
undetectable
5esmA-3j7aX:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr3 NAD-DEPENDENT
DEACETYLASE


(Thermotoga
maritima)
PF02146
(SIR2)
4 ILE A 245
PHE A   6
THR A  18
LEU A 187
None
0.82A 5esmA-3jr3A:
undetectable
5esmA-3jr3A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq5 HYPOTHETICAL
CYTOSOLIC PROTEIN


(Coxiella
burnetii)
PF07515
(TraI_2_C)
4 PHE A 225
ILE A 230
GLY A  91
LEU A  39
None
0.97A 5esmA-3kq5A:
undetectable
5esmA-3kq5A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kt4 PKHD-TYPE
HYDROXYLASE TPA1


(Saccharomyces
cerevisiae)
PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4)
4 PHE A 129
ILE A 168
GLY A  56
LEU A 189
None
0.98A 5esmA-3kt4A:
undetectable
5esmA-3kt4A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8k DIHYDROLIPOYL
DEHYDROGENASE


(Sulfolobus
solfataricus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 PHE A 189
ILE A 185
PHE A  74
THR A 164
None
0.94A 5esmA-3l8kA:
undetectable
5esmA-3l8kA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens)
PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N)
4 PHE A 589
ILE A 594
GLY A 243
THR A 229
None
0.83A 5esmA-3lppA:
undetectable
5esmA-3lppA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o80 HEXOKINASE

(Kluyveromyces
lactis)
PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2)
4 TYR A 284
ILE A 288
GLY A 310
LEU A 383
None
0.95A 5esmA-3o80A:
undetectable
5esmA-3o80A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o90 NICOTINAMIDASE

(Streptococcus
pneumoniae)
PF00857
(Isochorismatase)
4 TYR A 149
ILE A 151
THR A  51
LEU A 114
None
0.89A 5esmA-3o90A:
undetectable
5esmA-3o90A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1


(Bifidobacterium
longum)
PF01547
(SBP_bac_1)
4 PHE A 486
ILE A 485
PHE A 220
GLY A 246
None
0.92A 5esmA-3ombA:
undetectable
5esmA-3ombA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oss TYPE 2 SECRETION
SYSTEM, GSPC
TYPE 2 SECRETION
SYSTEM, SECRETIN
GSPD


(Escherichia
coli)
PF03958
(Secretin_N)
PF11356
(T2SSC)
4 TYR C 151
ILE C 167
GLY C 131
THR D  12
None
0.94A 5esmA-3ossC:
undetectable
5esmA-3ossC:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3u LIGNIN PEROXIDASE

(Trametopsis
cervina)
PF00141
(peroxidase)
PF11895
(Peroxidase_ext)
4 PHE A  29
ILE A  24
GLY A 113
THR A  45
None
1.02A 5esmA-3q3uA:
undetectable
5esmA-3q3uA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvn MANGANESE-CONTAINING
SUPEROXIDE DISMUTASE


(Candida
albicans)
PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C)
4 ILE A   8
GLY A  75
THR A 157
LEU A  82
None
1.01A 5esmA-3qvnA:
undetectable
5esmA-3qvnA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rap PROTEIN (G PROTEIN
RAP2A)


(Homo sapiens)
PF00071
(Ras)
4 ILE R  93
GLY R 115
THR R 145
LEU R 156
None
0.97A 5esmA-3rapR:
undetectable
5esmA-3rapR:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rih SHORT CHAIN
DEHYDROGENASE OR
REDUCTASE


(Mycobacteroides
abscessus)
PF13561
(adh_short_C2)
4 ILE A 107
GLY A 131
THR A 135
LEU A  76
None
0.97A 5esmA-3rihA:
undetectable
5esmA-3rihA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpf MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1 (MOAD)


(Helicobacter
pylori)
PF02597
(ThiS)
4 PHE C  16
ILE C  18
PHE C   7
LEU C  40
None
0.98A 5esmA-3rpfC:
undetectable
5esmA-3rpfC:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpu 42F3 BETA

(Homo sapiens;
Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 TYR B  64
GLY B  17
THR B  13
LEU B 108
None
1.01A 5esmA-3tpuB:
undetectable
5esmA-3tpuB:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0v L-LYSINE OXIDASE

(Trichoderma
viride)
PF01593
(Amino_oxidase)
4 TYR A  92
ILE A  90
GLY A 230
THR A  51
None
0.75A 5esmA-3x0vA:
undetectable
5esmA-3x0vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayj BOGT -
METAL-INDEPENDENT
GLYCOSYLTRANSFERASE


(Bacteroides
ovatus)
PF03414
(Glyco_transf_6)
4 PHE A 100
PHE A  94
THR A 120
LEU A 118
None
0.95A 5esmA-4ayjA:
undetectable
5esmA-4ayjA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db1 MYOSIN-7

(Homo sapiens)
PF00063
(Myosin_head)
PF02736
(Myosin_N)
4 PHE A 312
ILE A 356
GLY A 425
LEU A 399
None
0.79A 5esmA-4db1A:
undetectable
5esmA-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdu PUTATIVE MULTIPLE
INOSITOL
POLYPHOSPHATE
HISTIDINE
PHOSPHATASE 1


(Bacteroides
thetaiotaomicron)
PF00328
(His_Phos_2)
4 PHE A 408
ILE A 392
GLY A 335
THR A 339
None
0.95A 5esmA-4fduA:
0.5
5esmA-4fduA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g59 M152 PROTEIN

(Murid
betaherpesvirus
1)
PF11624
(M157)
4 PHE C  78
PHE C  95
GLY C 147
THR C 118
None
0.89A 5esmA-4g59C:
undetectable
5esmA-4g59C:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjl NAPHTHALENE
1,2-DIOXYGENASE
SUBUNIT ALPHA


(Pseudomonas sp.
C18)
PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
4 PHE A 432
GLY A 247
THR A 243
LEU A 443
None
0.90A 5esmA-4hjlA:
undetectable
5esmA-4hjlA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m46 LUCIFERASE

(Lampyris
turkestanicus)
PF00501
(AMP-binding)
4 ILE A 434
GLY A 341
THR A 345
LEU A 418
None
0.96A 5esmA-4m46A:
undetectable
5esmA-4m46A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN


(Pseudomonas
aeruginosa)
PF03480
(DctP)
4 PHE A 182
ILE A 172
GLY A 208
LEU A 216
None
0.95A 5esmA-4nf0A:
undetectable
5esmA-4nf0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqf PROTEIN RECA

(Mycobacterium
tuberculosis)
PF00154
(RecA)
4 TYR A  66
ILE A 193
GLY A  72
THR A 243
EDO  A 402 (-4.8A)
None
GOL  A 401 (-3.4A)
None
0.83A 5esmA-4oqfA:
undetectable
5esmA-4oqfA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN


(Aequorea
victoria;
Homo sapiens)
PF00063
(Myosin_head)
PF01353
(GFP)
PF02736
(Myosin_N)
4 PHE A 312
ILE A 356
GLY A 425
LEU A 399
None
0.77A 5esmA-4p7hA:
undetectable
5esmA-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pua GLUTATHIONE
S-TRANSFERASE


(Streptococcus
pneumoniae)
PF02798
(GST_N)
PF13410
(GST_C_2)
4 ILE A  80
GLY A  53
THR A  57
LEU A  75
GSH  A 302 ( 3.8A)
None
None
None
0.75A 5esmA-4puaA:
undetectable
5esmA-4puaA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgs ALCOHOL
DEHYDROGENASE YQHD


(Escherichia
coli)
PF00465
(Fe-ADH)
4 PHE A 163
ILE A 119
GLY A 100
LEU A  89
None
1.01A 5esmA-4qgsA:
undetectable
5esmA-4qgsA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7y MINICHROMOSOME
MAINTENANCE PROTEIN
MCM, CELL DIVISION
CONTROL PROTEIN 21


(Pyrococcus
furiosus;
Sulfolobus
solfataricus)
PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB)
4 ILE A1788
GLY A1740
THR A1738
LEU A 209
None
1.01A 5esmA-4r7yA:
undetectable
5esmA-4r7yA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv2 MAOC FAMILY PROTEIN
UPF0336 PROTEIN
MSMEG_1340/MSMEI_130
2


(Mycolicibacterium
smegmatis)
PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N)
4 PHE B 104
ILE B  20
GLY B  67
THR A  58
None
0.93A 5esmA-4rv2B:
undetectable
5esmA-4rv2B:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rz2 SITE-DETERMINING
PROTEIN


(Geobacillus
thermodenitrificans)
PF10609
(ParA)
4 PHE A 284
ILE A 119
PHE A 151
LEU A  78
None
0.94A 5esmA-4rz2A:
undetectable
5esmA-4rz2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2e FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 3


(Mus musculus)
PF01462
(LRRNT)
PF13855
(LRR_8)
4 ILE A 169
PHE A 221
GLY A 217
LEU A 237
None
1.03A 5esmA-4v2eA:
undetectable
5esmA-4v2eA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8y CRISPR SYSTEM CMR
SUBUNIT CMR2


(Pyrococcus
furiosus)
PF12469
(DUF3692)
4 PHE A 860
ILE A 863
PHE A 771
LEU A 781
None
1.00A 5esmA-4w8yA:
undetectable
5esmA-4w8yA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a55 ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE


(Streptococcus
pneumoniae)
PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C)
4 TYR A1266
PHE A1402
GLY A 730
LEU A 712
None
0.98A 5esmA-5a55A:
undetectable
5esmA-5a55A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6b N-ACETYL-BETA-D-GLUC
OSAMINIDASE


(Streptococcus
pneumoniae)
PF00728
(Glyco_hydro_20)
4 ILE D 617
GLY D 341
THR D 343
LEU D 494
None
0.84A 5esmA-5a6bD:
undetectable
5esmA-5a6bD:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1q U14 PROTEIN

(Human
betaherpesvirus
6B)
PF04637
(Herpes_pp85)
4 PHE A 316
PHE A  20
GLY A  85
LEU A  63
None
0.93A 5esmA-5b1qA:
undetectable
5esmA-5b1qA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN


(Staphylococcus
epidermidis)
no annotation 4 TYR A 439
ILE A 451
GLY A 335
LEU A 344
None
0.97A 5esmA-5bndA:
undetectable
5esmA-5bndA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7w SERRALYSIN

(Serratia
marcescens)
PF00353
(HemolysinCabind)
PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C)
4 ILE A 303
PHE A 281
GLY A 260
THR A 272
ILE  A 303 ( 0.7A)
PHE  A 281 ( 1.3A)
GLY  A 260 ( 0.0A)
THR  A 272 ( 0.8A)
1.03A 5esmA-5d7wA:
undetectable
5esmA-5d7wA:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fsa CYP51 VARIANT1

(Candida
albicans)
PF00067
(p450)
7 TYR A 118
PHE A 126
ILE A 131
PHE A 228
GLY A 307
THR A 311
LEU A 376
X2N  A 590 ( 4.0A)
X2N  A 590 (-4.8A)
X2N  A 590 (-4.2A)
X2N  A 590 (-4.9A)
X2N  A 590 (-3.5A)
HEM  A 580 (-3.6A)
X2N  A 590 (-4.3A)
0.63A 5esmA-5fsaA:
55.8
5esmA-5fsaA:
59.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gyz LUCIFERIN
4-MONOOXYGENASE


(Photinus
pyralis)
PF00501
(AMP-binding)
4 ILE A 434
GLY A 341
THR A 345
LEU A 418
AMP  A 501 ( 4.5A)
7BV  A 500 (-3.9A)
None
None
0.88A 5esmA-5gyzA:
undetectable
5esmA-5gyzA:
22.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hs1 LANOSTEROL 14-ALPHA
DEMETHYLASE


(Saccharomyces
cerevisiae)
PF00067
(p450)
7 TYR A 126
PHE A 134
ILE A 139
PHE A 236
GLY A 314
THR A 318
LEU A 380
VOR  A 602 ( 3.8A)
VOR  A 602 (-4.7A)
VOR  A 602 (-4.3A)
VOR  A 602 (-4.4A)
VOR  A 602 (-3.0A)
HEM  A 601 (-3.4A)
VOR  A 602 (-4.0A)
0.44A 5esmA-5hs1A:
63.8
5esmA-5hs1A:
99.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens)
PF01039
(Carboxyl_trans)
4 TYR A 258
PHE A 360
ILE A 315
LEU A 307
None
0.99A 5esmA-5infA:
undetectable
5esmA-5infA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz3 PREDICTED PROTEIN

(Physcomitrella
patens)
PF00316
(FBPase)
4 TYR B 366
ILE B 310
GLY B 265
LEU B 323
None
None
PO4  B 402 ( 4.1A)
None
0.91A 5esmA-5iz3B:
undetectable
5esmA-5iz3B:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbo BETA-GLUCOSIDASE

(Trichoderma
harzianum)
PF00232
(Glyco_hydro_1)
4 PHE A 275
ILE A 274
GLY A 312
THR A 383
None
0.82A 5esmA-5jboA:
undetectable
5esmA-5jboA:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE


([Candida]
glabrata)
PF00067
(p450)
6 TYR A 127
PHE A 135
ILE A 140
GLY A 315
THR A 319
LEU A 381
1YN  A 602 ( 3.8A)
1YN  A 602 ( 4.6A)
1YN  A 602 (-4.4A)
1YN  A 602 ( 3.6A)
HEM  A 601 ( 3.5A)
1YN  A 602 ( 4.7A)
0.55A 5esmA-5jlcA:
58.3
5esmA-5jlcA:
83.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE


([Candida]
glabrata)
PF00067
(p450)
6 TYR A 127
PHE A 135
ILE A 140
PHE A 237
THR A 319
LEU A 381
1YN  A 602 ( 3.8A)
1YN  A 602 ( 4.6A)
1YN  A 602 (-4.4A)
1YN  A 602 (-4.5A)
HEM  A 601 ( 3.5A)
1YN  A 602 ( 4.7A)
0.54A 5esmA-5jlcA:
58.3
5esmA-5jlcA:
83.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jrj PROTEIN RECA

(Herbaspirillum
seropedicae)
PF00154
(RecA)
4 TYR A  72
ILE A 199
GLY A  78
THR A 249
None
None
ADP  A 401 ( 3.2A)
None
0.99A 5esmA-5jrjA:
undetectable
5esmA-5jrjA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE


(Aspergillus
fumigatus)
PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC)
4 ILE A  95
GLY A  13
THR A  15
LEU A  69
None
None
SO4  A 402 (-3.2A)
None
0.99A 5esmA-5jw6A:
undetectable
5esmA-5jw6A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf2 PREDICTED
ACETYLTRANSFERASE


(Clostridium
acetobutylicum)
PF00583
(Acetyltransf_1)
4 PHE A 184
ILE A 220
PHE A 189
GLY A 254
None
None
COA  A 401 (-4.8A)
COA  A 401 (-3.3A)
0.92A 5esmA-5kf2A:
undetectable
5esmA-5kf2A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyv LUCIFERIN
4-MONOOXYGENASE


(Photinus
pyralis)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 ILE A 434
GLY A 341
THR A 345
LEU A 418
SLU  A 601 ( 4.3A)
SLU  A 601 (-4.0A)
None
None
0.90A 5esmA-5kyvA:
undetectable
5esmA-5kyvA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mif 'CARBOXYL ESTERASE 2

(Tuber
melanosporum)
PF07859
(Abhydrolase_3)
4 TYR A 164
PHE A 115
PHE A 186
LEU A 171
None
1.01A 5esmA-5mifA:
undetectable
5esmA-5mifA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mza ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)


(Plasmodium
falciparum)
PF05424
(Duffy_binding)
4 TYR A 951
PHE A 936
ILE A 939
LEU A 756
None
1.03A 5esmA-5mzaA:
undetectable
5esmA-5mzaA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhk O-GLCNACASE
TIM-BARREL DOMAIN


(Homo sapiens)
PF07555
(NAGidase)
4 PHE A 145
ILE A 198
PHE A 191
GLY A 140
None
0.91A 5esmA-5uhkA:
undetectable
5esmA-5uhkA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vev PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE


(Neisseria
gonorrhoeae)
PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N)
4 ILE A 196
PHE A 264
GLY A 266
LEU A  74
None
0.87A 5esmA-5vevA:
undetectable
5esmA-5vevA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wka BETA-GLUCOSIDASE

(metagenome)
no annotation 4 ILE A 284
GLY A 288
THR A 368
LEU A 112
None
0.79A 5esmA-5wkaA:
undetectable
5esmA-5wkaA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbp 3NT OXYGENASE ALPHA
SUBUNIT


(Diaphorobacter
sp. DS2)
PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
4 PHE A 430
GLY A 245
THR A 241
LEU A 441
None
0.89A 5esmA-5xbpA:
undetectable
5esmA-5xbpA:
23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ay4 CYP51, STEROL
14ALPHA-DEMETHYLASE


(Naegleria
fowleri)
no annotation 4 TYR A 107
PHE A 114
THR A 297
LEU A 358
TPF  A 506 (-4.2A)
TPF  A 506 (-4.4A)
HEM  A 501 (-3.4A)
TPF  A 506 ( 4.4A)
0.58A 5esmA-6ay4A:
42.8
5esmA-6ay4A:
33.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR


(Clostridium
perfringens)
no annotation 4 PHE A   9
ILE A  13
GLY A  58
LEU A  90
None
0.95A 5esmA-6azhA:
undetectable
5esmA-6azhA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d79 SULFATE TRANSPORTER
CYSZ


(Pseudomonas
fragi)
no annotation 4 TYR A 179
ILE A 177
GLY A 171
LEU A 216
None
0.96A 5esmA-6d79A:
1.3
5esmA-6d79A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eio ANTIFREEZE PROTEIN

(uncultured
bacterium)
no annotation 4 TYR A 144
ILE A 173
GLY A 132
LEU A 137
None
0.99A 5esmA-6eioA:
undetectable
5esmA-6eioA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f74 ALCOHOL OXIDASE

(Thermothelomyces
thermophila)
no annotation 4 TYR A 540
ILE A 435
GLY A 546
THR A 580
FAD  A 601 (-4.9A)
None
None
None
0.94A 5esmA-6f74A:
undetectable
5esmA-6f74A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsa -

(-)
no annotation 4 PHE A 312
ILE A 356
GLY A 425
LEU A 399
None
0.85A 5esmA-6fsaA:
1.2
5esmA-6fsaA:
undetectable