SIMILAR PATTERNS OF AMINO ACIDS FOR 5ESM_A_TPFA602_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a2o | CHEB METHYLESTERASE (Salmonellaenterica) |
PF00072(Response_reg)PF01339(CheB_methylest) | 4 | PHE A 199GLY A 167THR A 281LEU A 330 | None | 0.84A | 5esmA-1a2oA:0.0 | 5esmA-1a2oA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c30 | CARBAMOYL PHOSPHATESYNTHETASE: LARGESUBUNIT (Escherichiacoli) |
PF02142(MGS)PF02786(CPSase_L_D2)PF02787(CPSase_L_D3) | 4 | PHE A 928GLY A1046THR A1043LEU A 907 | NoneNoneORN A4010 ( 4.9A)ORN A4010 (-4.0A) | 0.92A | 5esmA-1c30A:0.0 | 5esmA-1c30A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1chd | CHEB METHYLESTERASE (Salmonellaenterica) |
PF01339(CheB_methylest) | 4 | PHE A 199GLY A 167THR A 281LEU A 330 | None | 0.83A | 5esmA-1chdA:undetectable | 5esmA-1chdA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnz | BARK AGGLUTININ I,POLYPEPTIDE A (Robiniapseudoacacia) |
PF00139(Lectin_legB) | 4 | TYR A 170PHE A 231PHE A 56LEU A 202 | None | 1.03A | 5esmA-1fnzA:undetectable | 5esmA-1fnzA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l0q | SURFACE LAYERPROTEIN (Methanosarcinamazei) |
PF00801(PKD)PF10282(Lactonase) | 4 | PHE A 294ILE A 6GLY A 248THR A 217 | None | 0.93A | 5esmA-1l0qA:undetectable | 5esmA-1l0qA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1llc | L-LACTATEDEHYDROGENASE (Lactobacilluscasei) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ILE A 281PHE A 200GLY A 193THR A 165 | None | 0.99A | 5esmA-1llcA:1.8 | 5esmA-1llcA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pww | LETHAL FACTOR (Bacillusanthracis) |
PF07737(ATLF)PF09156(Anthrax-tox_M) | 4 | PHE A 631ILE A 602THR A 619LEU A 574 | None | 1.03A | 5esmA-1pwwA:0.3 | 5esmA-1pwwA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rw9 | CHONDROITIN AC LYASE (Paenarthrobacteraurescens) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 4 | TYR A 406GLY A 492THR A 496LEU A 457 | None | 1.02A | 5esmA-1rw9A:undetectable | 5esmA-1rw9A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuo | PUTATIVEPHOSPHOMANNOMUTASE (Thermusthermophilus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | PHE A 14ILE A 12PHE A 120LEU A 68 | None | 1.02A | 5esmA-1tuoA:0.0 | 5esmA-1tuoA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhk | HYPOTHETICAL PROTEINYQEU (Bacillussubtilis) |
PF04452(Methyltrans_RNA) | 4 | ILE A 83PHE A 111GLY A 204LEU A 217 | None | 1.02A | 5esmA-1vhkA:undetectable | 5esmA-1vhkA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wky | ENDO-BETA-1,4-MANNANASE (Bacillus sp.JAMB-602) |
PF00150(Cellulase) | 4 | TYR A 271ILE A 268GLY A 278LEU A 243 | NoneNoneNone CL A 501 (-4.3A) | 0.92A | 5esmA-1wkyA:undetectable | 5esmA-1wkyA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 4 | PHE A 41ILE A 21GLY A 262LEU A 214 | None | 0.86A | 5esmA-1womA:undetectable | 5esmA-1womA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr8 | PHOSPHOGLYCOLATEPHOSPHATASE (Pyrococcushorikoshii) |
PF08282(Hydrolase_3) | 4 | TYR A 207PHE A 185GLY A 176THR A 13 | None | 1.02A | 5esmA-1wr8A:undetectable | 5esmA-1wr8A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x8v | CYTOCHROME P450 51 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | TYR A 76PHE A 83THR A 260LEU A 321 | ESL A 471 ( 3.8A)NoneHEM A 470 (-3.6A)HEM A 470 (-4.1A) | 0.90A | 5esmA-1x8vA:35.2 | 5esmA-1x8vA:28.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buy | PROTOCATECHUATE3,4-DIOXYGENASEALPHA CHAIN (Acinetobactersp. ADP1) |
PF00775(Dioxygenase_C) | 4 | ILE A 129PHE A 106GLY A 93LEU A 22 | None | 1.01A | 5esmA-2buyA:undetectable | 5esmA-2buyA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c0k | HEMOGLOBIN (Gasterophilusintestinalis) |
PF00042(Globin) | 4 | TYR A 140ILE A 142PHE A 135GLY A 73 | None | 0.94A | 5esmA-2c0kA:undetectable | 5esmA-2c0kA:14.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dt9 | ASPARTOKINASE (Thermusthermophilus) |
PF01842(ACT)PF13840(ACT_7) | 4 | ILE A 24PHE A 64GLY A 20LEU A 75 | None | 0.99A | 5esmA-2dt9A:undetectable | 5esmA-2dt9A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2epk | N-ACETYL-BETA-D-GLUCOSAMINIDASE (Streptococcusgordonii) |
PF00728(Glyco_hydro_20) | 4 | ILE X 618GLY X 342THR X 344LEU X 495 | None | 0.86A | 5esmA-2epkX:undetectable | 5esmA-2epkX:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7r | CXE CARBOXYLESTERASE (Actinidiaeriantha) |
PF07859(Abhydrolase_3) | 4 | PHE A 104ILE A 103GLY A 92LEU A 222 | NoneNone4PA A 369 (-3.5A)None | 0.69A | 5esmA-2o7rA:undetectable | 5esmA-2o7rA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ozj | CUPIN 2, CONSERVEDBARREL (Desulfitobacteriumhafniense) |
no annotation | 4 | TYR A 61ILE A 63PHE A 44GLY A 97 | None | 0.93A | 5esmA-2ozjA:undetectable | 5esmA-2ozjA:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2reb | REC A (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A 65ILE A 192GLY A 71THR A 242 | None | 0.82A | 5esmA-2rebA:undetectable | 5esmA-2rebA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfo | NUCLEOPORIN NIC96 (Saccharomycescerevisiae) |
PF04097(Nic96) | 4 | TYR A 556PHE A 534ILE A 537GLY A 509 | None | 0.75A | 5esmA-2rfoA:undetectable | 5esmA-2rfoA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vda | TRANSLOCASE SUBUNITSECA (Escherichiacoli) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 4 | PHE A 68ILE A 64GLY A 91LEU A 207 | None | 1.00A | 5esmA-2vdaA:undetectable | 5esmA-2vdaA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpi | GMP SYNTHASE (Homo sapiens) |
PF00117(GATase) | 4 | PHE A 140ILE A 202GLY A 176LEU A 151 | None | 1.03A | 5esmA-2vpiA:undetectable | 5esmA-2vpiA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wed | PENICILLOPEPSIN (Penicilliumjanthinellum) |
PF00026(Asp) | 4 | ILE A 260PHE A 208GLY A 210LEU A 219 | None | 0.90A | 5esmA-2wedA:undetectable | 5esmA-2wedA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wlc | POLYSIALIC ACIDO-ACETYLTRANSFERASE (Neisseriameningitidis) |
PF00132(Hexapep) | 4 | ILE A 139GLY A 104THR A 86LEU A 109 | NoneEDO A1218 (-3.5A)NoneNone | 0.80A | 5esmA-2wlcA:undetectable | 5esmA-2wlcA:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwu | IMPORTIN13 (Homo sapiens) |
PF03810(IBN_N)PF08389(Xpo1) | 4 | ILE B 84PHE B 61GLY B 78LEU B 30 | None | 0.99A | 5esmA-2xwuB:undetectable | 5esmA-2xwuB:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zah | COAT PROTEIN (Melon necroticspot virus) |
PF00729(Viral_coat) | 4 | ILE A 288PHE A 364GLY A 301LEU A 316 | None | 1.00A | 5esmA-2zahA:undetectable | 5esmA-2zahA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9g | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrobaculumaerophilum) |
PF07995(GSDH) | 4 | ILE A 344GLY A 280THR A 231LEU A 296 | None | 0.94A | 5esmA-3a9gA:undetectable | 5esmA-3a9gA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ccy | PUTATIVE TETR-FAMILYTRANSCRIPTIONALREGULATOR (Bordetellaparapertussis) |
PF00440(TetR_N) | 4 | TYR A 134PHE A 161ILE A 132PHE A 95 | None | 0.99A | 5esmA-3ccyA:undetectable | 5esmA-3ccyA:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cji | POLYPROTEIN (Senecavirus A) |
PF00073(Rhv) | 4 | PHE B 131PHE B 121GLY B 129LEU B 204 | None | 1.01A | 5esmA-3cjiB:undetectable | 5esmA-3cjiB:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A1065ILE A1192GLY A1071THR A1242 | NoneNoneANP A1400 (-3.1A)None | 0.84A | 5esmA-3cmvA:undetectable | 5esmA-3cmvA:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8b | FIDGETIN-LIKEPROTEIN 1 (Homo sapiens) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PHE A 486ILE A 539PHE A 524LEU A 559 | None | 0.86A | 5esmA-3d8bA:undetectable | 5esmA-3d8bA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fmb | DIMERIC PROTEIN OFUNKNOWN FUNCTION ANDFERREDOXIN-LIKE FOLD (Bacteroidesfragilis) |
PF07876(Dabb) | 4 | PHE A 8ILE A 57GLY A 82LEU A 33 | None | 0.65A | 5esmA-3fmbA:undetectable | 5esmA-3fmbA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3goc | ENDONUCLEASE V (Streptomycesavermitilis) |
PF04493(Endonuclease_5) | 4 | PHE A 124GLY A 131THR A 134LEU A 98 | None | 1.02A | 5esmA-3gocA:undetectable | 5esmA-3gocA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrd | NICOTINATEDEHYDROGENASEFAD-SUBUNIT (Eubacteriumbarkeri) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 4 | PHE C 77ILE C 80GLY C 112LEU C 148 | FAD C 900 (-4.2A)NoneFAD C 900 ( 4.3A)None | 0.87A | 5esmA-3hrdC:undetectable | 5esmA-3hrdC:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 1 (Thermusthermophilus) |
PF01512(Complex1_51K)PF10531(SLBB)PF10589(NADH_4Fe-4S) | 4 | ILE 1 149PHE 1 169GLY 1 130LEU 1 224 | None | 0.94A | 5esmA-3i9v1:undetectable | 5esmA-3i9v1:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iz3 | VIRAL STRUCTURALPROTEIN 5 (Cypovirus 1) |
no annotation | 4 | PHE D 31ILE D 19PHE D 179THR D 233 | None | 0.87A | 5esmA-3iz3D:undetectable | 5esmA-3iz3D:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7a | 40S RIBOSOMALPROTEIN US19 (Plasmodiumfalciparum) |
PF00203(Ribosomal_S19) | 4 | PHE X 37ILE X 112PHE X 45LEU X 57 | None | 0.95A | 5esmA-3j7aX:undetectable | 5esmA-3j7aX:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr3 | NAD-DEPENDENTDEACETYLASE (Thermotogamaritima) |
PF02146(SIR2) | 4 | ILE A 245PHE A 6THR A 18LEU A 187 | None | 0.82A | 5esmA-3jr3A:undetectable | 5esmA-3jr3A:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq5 | HYPOTHETICALCYTOSOLIC PROTEIN (Coxiellaburnetii) |
PF07515(TraI_2_C) | 4 | PHE A 225ILE A 230GLY A 91LEU A 39 | None | 0.97A | 5esmA-3kq5A:undetectable | 5esmA-3kq5A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kt4 | PKHD-TYPEHYDROXYLASE TPA1 (Saccharomycescerevisiae) |
PF10637(Ofd1_CTDD)PF13661(2OG-FeII_Oxy_4) | 4 | PHE A 129ILE A 168GLY A 56LEU A 189 | None | 0.98A | 5esmA-3kt4A:undetectable | 5esmA-3kt4A:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8k | DIHYDROLIPOYLDEHYDROGENASE (Sulfolobussolfataricus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | PHE A 189ILE A 185PHE A 74THR A 164 | None | 0.94A | 5esmA-3l8kA:undetectable | 5esmA-3l8kA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpp | SUCRASE-ISOMALTASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | PHE A 589ILE A 594GLY A 243THR A 229 | None | 0.83A | 5esmA-3lppA:undetectable | 5esmA-3lppA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o80 | HEXOKINASE (Kluyveromyceslactis) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | TYR A 284ILE A 288GLY A 310LEU A 383 | None | 0.95A | 5esmA-3o80A:undetectable | 5esmA-3o80A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o90 | NICOTINAMIDASE (Streptococcuspneumoniae) |
PF00857(Isochorismatase) | 4 | TYR A 149ILE A 151THR A 51LEU A 114 | None | 0.89A | 5esmA-3o90A:undetectable | 5esmA-3o90A:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3omb | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 1 (Bifidobacteriumlongum) |
PF01547(SBP_bac_1) | 4 | PHE A 486ILE A 485PHE A 220GLY A 246 | None | 0.92A | 5esmA-3ombA:undetectable | 5esmA-3ombA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oss | TYPE 2 SECRETIONSYSTEM, GSPCTYPE 2 SECRETIONSYSTEM, SECRETINGSPD (Escherichiacoli) |
PF03958(Secretin_N)PF11356(T2SSC) | 4 | TYR C 151ILE C 167GLY C 131THR D 12 | None | 0.94A | 5esmA-3ossC:undetectable | 5esmA-3ossC:8.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3u | LIGNIN PEROXIDASE (Trametopsiscervina) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | PHE A 29ILE A 24GLY A 113THR A 45 | None | 1.02A | 5esmA-3q3uA:undetectable | 5esmA-3q3uA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvn | MANGANESE-CONTAININGSUPEROXIDE DISMUTASE (Candidaalbicans) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | ILE A 8GLY A 75THR A 157LEU A 82 | None | 1.01A | 5esmA-3qvnA:undetectable | 5esmA-3qvnA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rap | PROTEIN (G PROTEINRAP2A) (Homo sapiens) |
PF00071(Ras) | 4 | ILE R 93GLY R 115THR R 145LEU R 156 | None | 0.97A | 5esmA-3rapR:undetectable | 5esmA-3rapR:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rih | SHORT CHAINDEHYDROGENASE ORREDUCTASE (Mycobacteroidesabscessus) |
PF13561(adh_short_C2) | 4 | ILE A 107GLY A 131THR A 135LEU A 76 | None | 0.97A | 5esmA-3rihA:undetectable | 5esmA-3rihA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpf | MOLYBDOPTERINCONVERTING FACTOR,SUBUNIT 1 (MOAD) (Helicobacterpylori) |
PF02597(ThiS) | 4 | PHE C 16ILE C 18PHE C 7LEU C 40 | None | 0.98A | 5esmA-3rpfC:undetectable | 5esmA-3rpfC:8.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tpu | 42F3 BETA (Homo sapiens;Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | TYR B 64GLY B 17THR B 13LEU B 108 | None | 1.01A | 5esmA-3tpuB:undetectable | 5esmA-3tpuB:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x0v | L-LYSINE OXIDASE (Trichodermaviride) |
PF01593(Amino_oxidase) | 4 | TYR A 92ILE A 90GLY A 230THR A 51 | None | 0.75A | 5esmA-3x0vA:undetectable | 5esmA-3x0vA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayj | BOGT -METAL-INDEPENDENTGLYCOSYLTRANSFERASE (Bacteroidesovatus) |
PF03414(Glyco_transf_6) | 4 | PHE A 100PHE A 94THR A 120LEU A 118 | None | 0.95A | 5esmA-4ayjA:undetectable | 5esmA-4ayjA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db1 | MYOSIN-7 (Homo sapiens) |
PF00063(Myosin_head)PF02736(Myosin_N) | 4 | PHE A 312ILE A 356GLY A 425LEU A 399 | None | 0.79A | 5esmA-4db1A:undetectable | 5esmA-4db1A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdu | PUTATIVE MULTIPLEINOSITOLPOLYPHOSPHATEHISTIDINEPHOSPHATASE 1 (Bacteroidesthetaiotaomicron) |
PF00328(His_Phos_2) | 4 | PHE A 408ILE A 392GLY A 335THR A 339 | None | 0.95A | 5esmA-4fduA:0.5 | 5esmA-4fduA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g59 | M152 PROTEIN (Muridbetaherpesvirus1) |
PF11624(M157) | 4 | PHE C 78PHE C 95GLY C 147THR C 118 | None | 0.89A | 5esmA-4g59C:undetectable | 5esmA-4g59C:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjl | NAPHTHALENE1,2-DIOXYGENASESUBUNIT ALPHA (Pseudomonas sp.C18) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | PHE A 432GLY A 247THR A 243LEU A 443 | None | 0.90A | 5esmA-4hjlA:undetectable | 5esmA-4hjlA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m46 | LUCIFERASE (Lampyristurkestanicus) |
PF00501(AMP-binding) | 4 | ILE A 434GLY A 341THR A 345LEU A 418 | None | 0.96A | 5esmA-4m46A:undetectable | 5esmA-4m46A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nf0 | PROBABLEC4-DICARBOXYLATE-BINDING PROTEIN (Pseudomonasaeruginosa) |
PF03480(DctP) | 4 | PHE A 182ILE A 172GLY A 208LEU A 216 | None | 0.95A | 5esmA-4nf0A:undetectable | 5esmA-4nf0A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqf | PROTEIN RECA (Mycobacteriumtuberculosis) |
PF00154(RecA) | 4 | TYR A 66ILE A 193GLY A 72THR A 243 | EDO A 402 (-4.8A)NoneGOL A 401 (-3.4A)None | 0.83A | 5esmA-4oqfA:undetectable | 5esmA-4oqfA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p7h | MYOSIN-7,GREENFLUORESCENT PROTEIN (Aequoreavictoria;Homo sapiens) |
PF00063(Myosin_head)PF01353(GFP)PF02736(Myosin_N) | 4 | PHE A 312ILE A 356GLY A 425LEU A 399 | None | 0.77A | 5esmA-4p7hA:undetectable | 5esmA-4p7hA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pua | GLUTATHIONES-TRANSFERASE (Streptococcuspneumoniae) |
PF02798(GST_N)PF13410(GST_C_2) | 4 | ILE A 80GLY A 53THR A 57LEU A 75 | GSH A 302 ( 3.8A)NoneNoneNone | 0.75A | 5esmA-4puaA:undetectable | 5esmA-4puaA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgs | ALCOHOLDEHYDROGENASE YQHD (Escherichiacoli) |
PF00465(Fe-ADH) | 4 | PHE A 163ILE A 119GLY A 100LEU A 89 | None | 1.01A | 5esmA-4qgsA:undetectable | 5esmA-4qgsA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7y | MINICHROMOSOMEMAINTENANCE PROTEINMCM, CELL DIVISIONCONTROL PROTEIN 21 (Pyrococcusfuriosus;Sulfolobussolfataricus) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 4 | ILE A1788GLY A1740THR A1738LEU A 209 | None | 1.01A | 5esmA-4r7yA:undetectable | 5esmA-4r7yA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv2 | MAOC FAMILY PROTEINUPF0336 PROTEINMSMEG_1340/MSMEI_1302 (Mycolicibacteriumsmegmatis) |
PF01575(MaoC_dehydratas)PF13452(MaoC_dehydrat_N) | 4 | PHE B 104ILE B 20GLY B 67THR A 58 | None | 0.93A | 5esmA-4rv2B:undetectable | 5esmA-4rv2B:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rz2 | SITE-DETERMININGPROTEIN (Geobacillusthermodenitrificans) |
PF10609(ParA) | 4 | PHE A 284ILE A 119PHE A 151LEU A 78 | None | 0.94A | 5esmA-4rz2A:undetectable | 5esmA-4rz2A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v2e | FIBRONECTIN LEUCINERICH TRANSMEMBRANEPROTEIN 3 (Mus musculus) |
PF01462(LRRNT)PF13855(LRR_8) | 4 | ILE A 169PHE A 221GLY A 217LEU A 237 | None | 1.03A | 5esmA-4v2eA:undetectable | 5esmA-4v2eA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8y | CRISPR SYSTEM CMRSUBUNIT CMR2 (Pyrococcusfuriosus) |
PF12469(DUF3692) | 4 | PHE A 860ILE A 863PHE A 771LEU A 781 | None | 1.00A | 5esmA-4w8yA:undetectable | 5esmA-4w8yA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a55 | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Streptococcuspneumoniae) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 4 | TYR A1266PHE A1402GLY A 730LEU A 712 | None | 0.98A | 5esmA-5a55A:undetectable | 5esmA-5a55A:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6b | N-ACETYL-BETA-D-GLUCOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 4 | ILE D 617GLY D 341THR D 343LEU D 494 | None | 0.84A | 5esmA-5a6bD:undetectable | 5esmA-5a6bD:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b1q | U14 PROTEIN (Humanbetaherpesvirus6B) |
PF04637(Herpes_pp85) | 4 | PHE A 316PHE A 20GLY A 85LEU A 63 | None | 0.93A | 5esmA-5b1qA:undetectable | 5esmA-5b1qA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bnd | ABC TRANSPORTER,ATP-BINDING PROTEIN (Staphylococcusepidermidis) |
no annotation | 4 | TYR A 439ILE A 451GLY A 335LEU A 344 | None | 0.97A | 5esmA-5bndA:undetectable | 5esmA-5bndA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d7w | SERRALYSIN (Serratiamarcescens) |
PF00353(HemolysinCabind)PF00413(Peptidase_M10)PF08548(Peptidase_M10_C) | 4 | ILE A 303PHE A 281GLY A 260THR A 272 | ILE A 303 ( 0.7A)PHE A 281 ( 1.3A)GLY A 260 ( 0.0A)THR A 272 ( 0.8A) | 1.03A | 5esmA-5d7wA:undetectable | 5esmA-5d7wA:19.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fsa | CYP51 VARIANT1 (Candidaalbicans) |
PF00067(p450) | 7 | TYR A 118PHE A 126ILE A 131PHE A 228GLY A 307THR A 311LEU A 376 | X2N A 590 ( 4.0A)X2N A 590 (-4.8A)X2N A 590 (-4.2A)X2N A 590 (-4.9A)X2N A 590 (-3.5A)HEM A 580 (-3.6A)X2N A 590 (-4.3A) | 0.63A | 5esmA-5fsaA:55.8 | 5esmA-5fsaA:59.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gyz | LUCIFERIN4-MONOOXYGENASE (Photinuspyralis) |
PF00501(AMP-binding) | 4 | ILE A 434GLY A 341THR A 345LEU A 418 | AMP A 501 ( 4.5A)7BV A 500 (-3.9A)NoneNone | 0.88A | 5esmA-5gyzA:undetectable | 5esmA-5gyzA:22.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 7 | TYR A 126PHE A 134ILE A 139PHE A 236GLY A 314THR A 318LEU A 380 | VOR A 602 ( 3.8A)VOR A 602 (-4.7A)VOR A 602 (-4.3A)VOR A 602 (-4.4A)VOR A 602 (-3.0A)HEM A 601 (-3.4A)VOR A 602 (-4.0A) | 0.44A | 5esmA-5hs1A:63.8 | 5esmA-5hs1A:99.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5inf | CARBOXYL TRANSFERASE (Streptomycesambofaciens) |
PF01039(Carboxyl_trans) | 4 | TYR A 258PHE A 360ILE A 315LEU A 307 | None | 0.99A | 5esmA-5infA:undetectable | 5esmA-5infA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iz3 | PREDICTED PROTEIN (Physcomitrellapatens) |
PF00316(FBPase) | 4 | TYR B 366ILE B 310GLY B 265LEU B 323 | NoneNonePO4 B 402 ( 4.1A)None | 0.91A | 5esmA-5iz3B:undetectable | 5esmA-5iz3B:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbo | BETA-GLUCOSIDASE (Trichodermaharzianum) |
PF00232(Glyco_hydro_1) | 4 | PHE A 275ILE A 274GLY A 312THR A 383 | None | 0.82A | 5esmA-5jboA:undetectable | 5esmA-5jboA:21.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 6 | TYR A 127PHE A 135ILE A 140GLY A 315THR A 319LEU A 381 | 1YN A 602 ( 3.8A)1YN A 602 ( 4.6A)1YN A 602 (-4.4A)1YN A 602 ( 3.6A)HEM A 601 ( 3.5A)1YN A 602 ( 4.7A) | 0.55A | 5esmA-5jlcA:58.3 | 5esmA-5jlcA:83.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 6 | TYR A 127PHE A 135ILE A 140PHE A 237THR A 319LEU A 381 | 1YN A 602 ( 3.8A)1YN A 602 ( 4.6A)1YN A 602 (-4.4A)1YN A 602 (-4.5A)HEM A 601 ( 3.5A)1YN A 602 ( 4.7A) | 0.54A | 5esmA-5jlcA:58.3 | 5esmA-5jlcA:83.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jrj | PROTEIN RECA (Herbaspirillumseropedicae) |
PF00154(RecA) | 4 | TYR A 72ILE A 199GLY A 78THR A 249 | NoneNoneADP A 401 ( 3.2A)None | 0.99A | 5esmA-5jrjA:undetectable | 5esmA-5jrjA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jw6 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Aspergillusfumigatus) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | ILE A 95GLY A 13THR A 15LEU A 69 | NoneNoneSO4 A 402 (-3.2A)None | 0.99A | 5esmA-5jw6A:undetectable | 5esmA-5jw6A:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf2 | PREDICTEDACETYLTRANSFERASE (Clostridiumacetobutylicum) |
PF00583(Acetyltransf_1) | 4 | PHE A 184ILE A 220PHE A 189GLY A 254 | NoneNoneCOA A 401 (-4.8A)COA A 401 (-3.3A) | 0.92A | 5esmA-5kf2A:undetectable | 5esmA-5kf2A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kyv | LUCIFERIN4-MONOOXYGENASE (Photinuspyralis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ILE A 434GLY A 341THR A 345LEU A 418 | SLU A 601 ( 4.3A)SLU A 601 (-4.0A)NoneNone | 0.90A | 5esmA-5kyvA:undetectable | 5esmA-5kyvA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mif | 'CARBOXYL ESTERASE 2 (Tubermelanosporum) |
PF07859(Abhydrolase_3) | 4 | TYR A 164PHE A 115PHE A 186LEU A 171 | None | 1.01A | 5esmA-5mifA:undetectable | 5esmA-5mifA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mza | ERYTHROCYTE MEMBRANEPROTEIN 1 (PFEMP1) (Plasmodiumfalciparum) |
PF05424(Duffy_binding) | 4 | TYR A 951PHE A 936ILE A 939LEU A 756 | None | 1.03A | 5esmA-5mzaA:undetectable | 5esmA-5mzaA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhk | O-GLCNACASETIM-BARREL DOMAIN (Homo sapiens) |
PF07555(NAGidase) | 4 | PHE A 145ILE A 198PHE A 191GLY A 140 | None | 0.91A | 5esmA-5uhkA:undetectable | 5esmA-5uhkA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vev | PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (Neisseriagonorrhoeae) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | ILE A 196PHE A 264GLY A 266LEU A 74 | None | 0.87A | 5esmA-5vevA:undetectable | 5esmA-5vevA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wka | BETA-GLUCOSIDASE (metagenome) |
no annotation | 4 | ILE A 284GLY A 288THR A 368LEU A 112 | None | 0.79A | 5esmA-5wkaA:undetectable | 5esmA-5wkaA:10.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbp | 3NT OXYGENASE ALPHASUBUNIT (Diaphorobactersp. DS2) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | PHE A 430GLY A 245THR A 241LEU A 441 | None | 0.89A | 5esmA-5xbpA:undetectable | 5esmA-5xbpA:23.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ay4 | CYP51, STEROL14ALPHA-DEMETHYLASE (Naegleriafowleri) |
no annotation | 4 | TYR A 107PHE A 114THR A 297LEU A 358 | TPF A 506 (-4.2A)TPF A 506 (-4.4A)HEM A 501 (-3.4A)TPF A 506 ( 4.4A) | 0.58A | 5esmA-6ay4A:42.8 | 5esmA-6ay4A:33.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6azh | TETR FAMILYTRANSCRIPTIONALREGULATOR (Clostridiumperfringens) |
no annotation | 4 | PHE A 9ILE A 13GLY A 58LEU A 90 | None | 0.95A | 5esmA-6azhA:undetectable | 5esmA-6azhA:10.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d79 | SULFATE TRANSPORTERCYSZ (Pseudomonasfragi) |
no annotation | 4 | TYR A 179ILE A 177GLY A 171LEU A 216 | None | 0.96A | 5esmA-6d79A:1.3 | 5esmA-6d79A:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eio | ANTIFREEZE PROTEIN (unculturedbacterium) |
no annotation | 4 | TYR A 144ILE A 173GLY A 132LEU A 137 | None | 0.99A | 5esmA-6eioA:undetectable | 5esmA-6eioA:9.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f74 | ALCOHOL OXIDASE (Thermothelomycesthermophila) |
no annotation | 4 | TYR A 540ILE A 435GLY A 546THR A 580 | FAD A 601 (-4.9A)NoneNoneNone | 0.94A | 5esmA-6f74A:undetectable | 5esmA-6f74A:11.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fsa | - (-) |
no annotation | 4 | PHE A 312ILE A 356GLY A 425LEU A 399 | None | 0.85A | 5esmA-6fsaA:1.2 | 5esmA-6fsaA:undetectable |