SIMILAR PATTERNS OF AMINO ACIDS FOR 5ERS_A_ACTA803_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1buc | BUTYRYL-COADEHYDROGENASE (Megasphaeraelsdenii) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 162ALA A 92ASN A 163 | CAA A 384 ( 3.8A)CAA A 384 ( 4.2A)None | 0.40A | 5ersA-1bucA:undetectable | 5ersA-1bucA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbv | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Geobacillusstearothermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 151ALA O 147ASN O 152 | None | 0.60A | 5ersA-1dbvO:undetectable | 5ersA-1dbvO:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASESMALL SUBUNIT[NIFE] HYDROGENASELARGE SUBUNIT (Desulfovibriodesulfuricans;Desulfovibriodesulfuricans) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C)PF00374(NiFeSe_Hases) | 3 | THR B 177ALA A 59ASN B 178 | None | 0.56A | 5ersA-1e3dB:undetectable | 5ersA-1e3dB:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gae | D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 151ALA O 147ASN O 152 | None | 0.60A | 5ersA-1gaeO:2.9 | 5ersA-1gaeO:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gyq | PROTEIN(GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE) (Leishmaniamexicana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 168ALA A 164ASN A 169 | None | 0.59A | 5ersA-1gyqA:2.6 | 5ersA-1gyqA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hdg | HOLO-D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Thermotogamaritima) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 151ALA O 147ASN O 152 | None | 0.55A | 5ersA-1hdgO:undetectable | 5ersA-1hdgO:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hxj | BETA-GLUCOSIDASE (Zea mays) |
PF00232(Glyco_hydro_1) | 3 | THR A 400ALA A 254ASN A 326 | None | 0.62A | 5ersA-1hxjA:undetectable | 5ersA-1hxjA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ivh | ISOVALERYL-COADEHYDROGENASE (Homo sapiens) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 168ALA A 99ASN A 169 | FAD A 399 (-4.0A)FAD A 399 ( 4.8A)None | 0.38A | 5ersA-1ivhA:undetectable | 5ersA-1ivhA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jn0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA (Spinaciaoleracea) |
no annotation | 3 | THR O 151ALA O 147ASN O 152 | None | 0.62A | 5ersA-1jn0O:undetectable | 5ersA-1jn0O:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1obf | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Achromobacterxylosoxidans) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 156ALA O 152ASN O 157 | None | 0.59A | 5ersA-1obfO:2.0 | 5ersA-1obfO:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pqu | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Haemophilusinfluenzae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 3 | THR A 79ALA A 101ASN A 80 | None | 0.60A | 5ersA-1pquA:2.6 | 5ersA-1pquA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5a | EP-CADHERIN (Mus musculus) |
PF00028(Cadherin) | 3 | THR A 273ALA A 257ASN A 278 | NAG A 803 (-2.6A)NoneNone | 0.34A | 5ersA-1q5aA:undetectable | 5ersA-1q5aA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ry9 | SURFACE PRESENTATIONOF ANTIGENS PROTEINSPAK (Shigellaflexneri) |
PF03519(Invas_SpaK) | 3 | THR A 34ALA A 42ASN A 44 | None | 0.60A | 5ersA-1ry9A:undetectable | 5ersA-1ry9A:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1shz | GUANINENUCLEOTIDE-BINDINGPROTEINGALPHA(13):GALPHA(I1) CHIMERA (Mus musculus;Rattusnorvegicus) |
PF00503(G-alpha) | 3 | THR A 87ALA A 199ASN A 91 | None | 0.60A | 5ersA-1shzA:2.1 | 5ersA-1shzA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ska | 3-PHYTASE A (Aspergillusfumigatus) |
PF00328(His_Phos_2) | 3 | THR A 297ALA A 433ASN A 298 | None | 0.63A | 5ersA-1skaA:undetectable | 5ersA-1skaA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6p | PHENYLALANINEAMMONIA-LYASE (Rhodotorulatoruloides) |
PF00221(Lyase_aromatic) | 3 | THR A 513ALA A 282ASN A 517 | None | 0.53A | 5ersA-1t6pA:undetectable | 5ersA-1t6pA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 3 | THR B 330ALA B 12ASN B 14 | None | 0.64A | 5ersA-1tqyB:undetectable | 5ersA-1tqyB:25.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1um4 | ANTIBODY 21H3 HCHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR H 29ALA H 25ASN H 78 | None | 0.63A | 5ersA-1um4H:undetectable | 5ersA-1um4H:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vc2 | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Thermusthermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 151ALA A 147ASN A 152 | None | 0.58A | 5ersA-1vc2A:2.1 | 5ersA-1vc2A:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8c | S-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE (Clostridiumacetobutylicum) |
PF13649(Methyltransf_25) | 3 | THR A 49ALA A 8ASN A 51 | None | 0.61A | 5ersA-1y8cA:undetectable | 5ersA-1y8cA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ywg | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Plasmodiumfalciparum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 155ALA O 151ASN O 156 | None | 0.54A | 5ersA-1ywgO:undetectable | 5ersA-1ywgO:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zca | G ALPHA I/12 (Mus musculus) |
PF00503(G-alpha) | 3 | THR A 94ALA A 202ASN A 98 | None | 0.48A | 5ersA-1zcaA:2.6 | 5ersA-1zcaA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d2i | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Synechococcussp.) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 157ALA A 153ASN A 158 | None | 0.60A | 5ersA-2d2iA:undetectable | 5ersA-2d2iA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ep7 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Aquifexaeolicus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 154ALA A 150ASN A 155 | None | 0.62A | 5ersA-2ep7A:2.1 | 5ersA-2ep7A:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hr7 | INSULIN RECEPTOR (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 3 | THR A 461ALA A 458ASN A 462 | GOL A 597 (-3.0A)GOL A 597 (-3.6A)None | 0.52A | 5ersA-2hr7A:undetectable | 5ersA-2hr7A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i5p | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE1 (Kluyveromycesmarxianus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 151ALA O 147ASN O 152 | None | 0.55A | 5ersA-2i5pO:2.3 | 5ersA-2i5pO:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qr4 | PEPTIDASE M3B,OLIGOENDOPEPTIDASE F (Enterococcusfaecium) |
PF01432(Peptidase_M3)PF08439(Peptidase_M3_N) | 3 | THR A 423ALA A 534ASN A 427 | None | 0.54A | 5ersA-2qr4A:undetectable | 5ersA-2qr4A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ri8 | MANNOSYL-OLIGOSACCHARIDEALPHA-1,2-MANNOSIDASE (Penicilliumcitrinum) |
PF01532(Glyco_hydro_47) | 3 | THR A1193ALA A1256ASN A1249 | None | 0.51A | 5ersA-2ri8A:undetectable | 5ersA-2ri8A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0n | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,GLYCOSOMAL (Trypanosomabrucei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 167ALA A 163ASN A 168 | None | 0.64A | 5ersA-2x0nA:undetectable | 5ersA-2x0nA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b20 | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE(NADP+) (Synechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 157ALA A 153ASN A 158 | None | 0.56A | 5ersA-3b20A:undetectable | 5ersA-3b20A:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cps | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Cryptosporidiumparvum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 170ALA A 166ASN A 171 | None | 0.58A | 5ersA-3cpsA:4.1 | 5ersA-3cpsA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cx6 | GUANINENUCLEOTIDE-BINDINGPROTEIN ALPHA-13SUBUNIT (Mus musculus) |
PF00503(G-alpha) | 3 | THR A 87ALA A 199ASN A 91 | None | 0.58A | 5ersA-3cx6A:3.3 | 5ersA-3cx6A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3doc | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Brucellaabortus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 155ALA A 151ASN A 156 | None | 0.61A | 5ersA-3docA:undetectable | 5ersA-3docA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e6a | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Oryza sativa) |
no annotation | 3 | THR O 156ALA O 152ASN O 157 | SO4 O6921 (-4.8A)NoneNone | 0.62A | 5ersA-3e6aO:undetectable | 5ersA-3e6aO:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezy | DEHYDROGENASE (Thermotogamaritima) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 3 | THR A 289ALA A 301ASN A 293 | None | 0.63A | 5ersA-3ezyA:2.9 | 5ersA-3ezyA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3faj | PUTATIVEUNCHARACTERIZEDPROTEIN (Acidianustwo-tailedvirus) |
no annotation | 3 | THR A 107ALA A 12ASN A 111 | NoneNone CL A 132 (-4.3A) | 0.53A | 5ersA-3fajA:undetectable | 5ersA-3fajA:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnq | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE, TYPEI (Burkholderiapseudomallei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 156ALA A 152ASN A 157 | None | 0.58A | 5ersA-3gnqA:undetectable | 5ersA-3gnqA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ham | AMINOGLYCOSIDEPHOSPHOTRANSFERASE (Enterococcusfaecium) |
PF01636(APH) | 3 | THR A 170ALA A 294ASN A 174 | None | 0.57A | 5ersA-3hamA:undetectable | 5ersA-3hamA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hja | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Borreliellaburgdorferi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 155ALA A 151ASN A 156 | None | 0.54A | 5ersA-3hjaA:2.2 | 5ersA-3hjaA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iyl | VP1 (Aquareovirus C) |
PF06016(Reovirus_L2) | 3 | THR W 435ALA W 804ASN W1009 | None | 0.57A | 5ersA-3iylW:2.4 | 5ersA-3iylW:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2b | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 151ALA A 147ASN A 152 | None | 0.58A | 5ersA-3k2bA:2.1 | 5ersA-3k2bA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ksd | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE1 (Staphylococcusaureus) |
no annotation | 3 | THR Q 153ALA Q 149ASN Q 154 | None | 0.61A | 5ersA-3ksdQ:undetectable | 5ersA-3ksdQ:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l0d | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bartonellahenselae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 155ALA A 151ASN A 156 | None | 0.58A | 5ersA-3l0dA:undetectable | 5ersA-3l0dA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mde | MEDIUM CHAINACYL-COADEHYDROGENASE (Sus scrofa) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 168ALA A 100ASN A 169 | FAD A 399 (-4.0A)CO8 A 400 ( 4.2A)None | 0.43A | 5ersA-3mdeA:undetectable | 5ersA-3mdeA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkh | NITROALKANE OXIDASE (Podosporaanserina) |
PF00441(Acyl-CoA_dh_1)PF02771(Acyl-CoA_dh_N) | 3 | THR A 172ALA A 98ASN A 173 | FAD A 500 (-3.9A)FAD A 500 ( 4.9A)None | 0.43A | 5ersA-3mkhA:undetectable | 5ersA-3mkhA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5l | BINDING PROTEINCOMPONENT OF ABCPHOSPHONATETRANSPORTER (Pseudomonasaeruginosa) |
PF12974(Phosphonate-bd) | 3 | THR A 291ALA A 163ASN A 295 | NoneEDO A 411 (-3.9A)EDO A 411 (-3.7A) | 0.60A | 5ersA-3n5lA:2.7 | 5ersA-3n5lA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otn | SUSD SUPERFAMILYPROTEIN (Parabacteroidesdistasonis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 3 | THR A 425ALA A 429ASN A 426 | None | 0.50A | 5ersA-3otnA:undetectable | 5ersA-3otnA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owa | ACYL-COADEHYDROGENASE (Bacillusanthracis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 185ALA A 114ASN A 186 | FAD A 601 (-3.9A)NoneNone | 0.34A | 5ersA-3owaA:undetectable | 5ersA-3owaA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pym | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE3 (Saccharomycescerevisiae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 152ALA A 148ASN A 153 | None | 0.57A | 5ersA-3pymA:2.2 | 5ersA-3pymA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4u | PHND, SUBUNIT OFALKYLPHOSPHONATE ABCTRANSPORTER (Escherichiacoli) |
PF12974(Phosphonate-bd) | 3 | THR A 159ALA A 155ASN A 160 | None | 0.62A | 5ersA-3s4uA:2.2 | 5ersA-3s4uA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s83 | GGDEF FAMILY PROTEIN (Caulobactervibrioides) |
PF00563(EAL) | 3 | THR A 402ALA A 363ASN A 406 | None | 0.54A | 5ersA-3s83A:undetectable | 5ersA-3s83A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sth | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Toxoplasmagondii) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 154ALA A 150ASN A 155 | None | 0.57A | 5ersA-3sthA:2.5 | 5ersA-3sthA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 3 | THR A 48ALA A 149ASN A 52 | None | 0.61A | 5ersA-3umaA:undetectable | 5ersA-3umaA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdf | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Thermosynechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 156ALA A 152ASN A 157 | None | 0.53A | 5ersA-3zdfA:undetectable | 5ersA-3zdfA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a01 | PROTONPYROPHOSPHATASE (Vigna radiata) |
PF03030(H_PPase) | 3 | THR A 426ALA A 538ASN A 685 | None | 0.58A | 5ersA-4a01A:undetectable | 5ersA-4a01A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akk | NITRATE REGULATORYPROTEIN (Klebsiellaoxytoca) |
PF03861(ANTAR)PF08376(NIT) | 3 | THR A 129ALA A 177ASN A 54 | NoneEDO A1392 (-3.3A)EDO A1392 (-4.2A) | 0.59A | 5ersA-4akkA:undetectable | 5ersA-4akkA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dib | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bacillusanthracis) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 153ALA A 149ASN A 154 | None | 0.56A | 5ersA-4dibA:2.2 | 5ersA-4dibA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4edp | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Clostridiumperfringens) |
PF13416(SBP_bac_8) | 3 | THR A 263ALA A 94ASN A 265 | None | 0.50A | 5ersA-4edpA:undetectable | 5ersA-4edpA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjf | GGDEF FAMILY PROTEIN (Caulobactervibrioides) |
PF00563(EAL) | 3 | THR A 402ALA A 363ASN A 406 | None | 0.58A | 5ersA-4hjfA:undetectable | 5ersA-4hjfA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irn | PROLYL-ACPDEHYDROGENASE ([Oscillatoria]sp. PCC 6506) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 160ALA A 91ASN A 161 | FAD A 400 (-3.9A)NoneNone | 0.48A | 5ersA-4irnA:undetectable | 5ersA-4irnA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k9d | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Brugia malayi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 159ALA A 155ASN A 160 | None | 0.56A | 5ersA-4k9dA:2.0 | 5ersA-4k9dA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ksi | LEUCINEAMINOPEPTIDASE 1,CHLOROPLASTIC (Solanumlycopersicum) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 3 | THR A 515ALA A 428ASN A 514 | NoneSO4 A 603 (-4.0A)None | 0.53A | 5ersA-4ksiA:1.9 | 5ersA-4ksiA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kto | ISOVALERYL-COADEHYDROGENASE (Sinorhizobiummeliloti) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 163ALA A 94ASN A 164 | FAD A 401 (-4.0A)NoneNone | 0.34A | 5ersA-4ktoA:undetectable | 5ersA-4ktoA:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1f | ACYL-COADEHYDROGENASE DOMAINPROTEIN (Acidaminococcusfermentans) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 158ALA A 89ASN A 159 | FAD A 401 (-3.9A)NoneNone | 0.34A | 5ersA-4l1fA:undetectable | 5ersA-4l1fA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lsm | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Trypanosomacruzi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 158ALA A 154ASN A 159 | None | 0.55A | 5ersA-4lsmA:3.6 | 5ersA-4lsmA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o59 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Bos taurus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 151ALA O 147ASN O 152 | None | 0.54A | 5ersA-4o59O:4.3 | 5ersA-4o59O:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o5m | ISOVALERYL-COADEHYDROGENASE (Brucella suis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | THR A 158ALA A 89ASN A 159 | None | 0.35A | 5ersA-4o5mA:undetectable | 5ersA-4o5mA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p8r | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Trypanosomabrucei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 152ALA A 148ASN A 153 | None | 0.57A | 5ersA-4p8rA:undetectable | 5ersA-4p8rA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qqr | 3,5-EPIMERASE/4-REDUCTASE (Arabidopsisthaliana) |
PF04321(RmlD_sub_bind) | 3 | THR A 163ALA A 112ASN A 110 | None | 0.64A | 5ersA-4qqrA:3.0 | 5ersA-4qqrA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rdq | BESTROPHIN-1 (Gallus gallus) |
PF01062(Bestrophin) | 3 | THR A 307ALA A 146ASN A 308 | GOL A 501 (-4.8A)GOL A 501 (-3.2A)GOL A 501 (-4.6A) | 0.57A | 5ersA-4rdqA:undetectable | 5ersA-4rdqA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr2 | SUBTILISIN-LIKE 1SERINE PROTEASE (Plasmodiumvivax) |
PF00082(Peptidase_S8) | 3 | THR A 531ALA A 73ASN A 532 | None | 0.49A | 5ersA-4tr2A:4.2 | 5ersA-4tr2A:21.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4u90 | GEPHYRIN (Rattusnorvegicus) |
PF00994(MoCF_biosynth)PF03453(MoeA_N)PF03454(MoeA_C) | 3 | THR A 342ALA A 356ASN A 496 | None | 0.11A | 5ersA-4u90A:51.1 | 5ersA-4u90A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9i | PERIPLASMIC [NIFE]HYDROGENASE LARGESUBUNITPERIPLASMIC [NIFE]HYDROGENASE SMALLSUBUNIT (Desulfovibriovulgaris;Desulfovibriovulgaris) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 3 | THR L 187ALA S 59ASN L 188 | None | 0.57A | 5ersA-4u9iL:undetectable | 5ersA-4u9iL:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x90 | GROUP XVPHOSPHOLIPASE A2 (Homo sapiens) |
PF02450(LCAT) | 3 | THR A 281ALA A 133ASN A 135 | None | 0.36A | 5ersA-4x90A:1.6 | 5ersA-4x90A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xee | NEUROTENSIN RECEPTORTYPE 1, ENDOLYSINCHIMERA (Rattusnorvegicus;Escherichiavirus T4) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 3 | THR A 265ALA A1093ASN A1002 | None | 0.55A | 5ersA-4xeeA:undetectable | 5ersA-4xeeA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxb | INSULIN RECEPTOR (Homo sapiens) |
PF00041(fn3)PF00757(Furin-like)PF01030(Recep_L_domain) | 3 | THR E 461ALA E 458ASN E 462 | None | 0.50A | 5ersA-4zxbE:undetectable | 5ersA-4zxbE:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ap9 | LIPASE (Thermomyceslanuginosus) |
PF01764(Lipase_3)PF03893(Lipase3_N) | 3 | THR A 199ALA A 257ASN A 200 | None | 0.50A | 5ersA-5ap9A:undetectable | 5ersA-5ap9A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3r | IMP-18 (Pseudomonasaeruginosa) |
no annotation | 3 | THR A 120ALA A 116ASN A 121 | None | 0.61A | 5ersA-5b3rA:undetectable | 5ersA-5b3rA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c7i | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Mus musculus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 258ALA O 254ASN O 259 | None | 0.55A | 5ersA-5c7iO:undetectable | 5ersA-5c7iO:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c7o | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Homo sapiens) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR O 226ALA O 222ASN O 227 | NoneNoneOCS O 224 ( 4.8A) | 0.55A | 5ersA-5c7oO:2.3 | 5ersA-5c7oO:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ch8 | MONO- ANDDIACYLGLYCEROLLIPASE (Penicilliumcyclopium) |
PF01764(Lipase_3)PF03893(Lipase3_N) | 3 | THR A 197ALA A 258ASN A 198 | CL A 305 (-2.9A) CL A 305 ( 3.9A) CL A 305 ( 4.6A) | 0.52A | 5ersA-5ch8A:undetectable | 5ersA-5ch8A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9h | ISOCITRATE LYASE (Fusariumgraminearum) |
PF00463(ICL) | 3 | THR A 130ALA A 116ASN A 134 | None | 0.61A | 5ersA-5e9hA:undetectable | 5ersA-5e9hA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyy | CENTROLOBIUMTOMENTOSUM LECTIN (Centrolobiumtomentosum) |
PF00139(Lectin_legB) | 3 | THR A 116ALA A 122ASN A 119 | NoneNAG A 301 ( 3.8A)NAG A 301 (-1.6A) | 0.62A | 5ersA-5eyyA:undetectable | 5ersA-5eyyA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 3 | THR A 377ALA A 625ASN A 375 | None | 0.59A | 5ersA-5h42A:undetectable | 5ersA-5h42A:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5im2 | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNAL (Rhodoferaxferrireducens) |
PF03480(DctP) | 3 | THR A 114ALA A 118ASN A 115 | None | 0.59A | 5ersA-5im2A:undetectable | 5ersA-5im2A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iy9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Homo sapiens) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 3 | THR A 316ALA A 328ASN A 320 | None | 0.63A | 5ersA-5iy9A:undetectable | 5ersA-5iy9A:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jcf | MELANOMADIFFERENTIATIONASSOCIATED PROTEIN-5 (Gallus gallus) |
PF00271(Helicase_C)PF04851(ResIII)PF11648(RIG-I_C-RD) | 3 | THR A 785ALA A 789ASN A 786 | G X 6 ( 4.6A)None G X 6 ( 4.1A) | 0.41A | 5ersA-5jcfA:undetectable | 5ersA-5jcfA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqv | INSULINRECEPTOR,INSULINRECEPTOR (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 3 | THR E 461ALA E 458ASN E 462 | None | 0.50A | 5ersA-5kqvE:undetectable | 5ersA-5kqvE:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ld5 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Atopobiumvaginae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 170ALA A 166ASN A 171 | None | 0.57A | 5ersA-5ld5A:2.4 | 5ersA-5ld5A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mmd | METALLO-BETA-LACTAMASE 1 (Acinetobacterbaumannii) |
PF00753(Lactamase_B) | 3 | THR E 142ALA E 138ASN E 143 | None | 0.59A | 5ersA-5mmdE:undetectable | 5ersA-5mmdE:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ACYL-COADEHYDROGENASE (Clostridioidesdifficile) |
no annotation | 3 | THR C 157ALA C 88ASN C 158 | FAD C 401 (-3.7A)NoneNone | 0.40A | 5ersA-5ol2C:undetectable | 5ersA-5ol2C:24.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olj | DIPEPTIDYL PEPTIDASEIV (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 3 | THR A 441ALA A 38ASN A 460 | None | 0.59A | 5ersA-5oljA:3.0 | 5ersA-5oljA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u38 | LECTIN (Platypodiumelegans) |
PF00139(Lectin_legB) | 3 | THR A 116ALA A 122ASN A 119 | NoneNAG A 301 (-3.5A)NAG A 301 (-1.8A) | 0.60A | 5ersA-5u38A:undetectable | 5ersA-5u38A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 3 | THR A 421ALA A 414ASN A 424 | CIT A 503 (-3.1A) NA A 502 ( 3.9A)None | 0.55A | 5ersA-5uldA:undetectable | 5ersA-5uldA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Naegleriagruberi) |
no annotation | 3 | THR A 151ALA A 147ASN A 152 | None | 0.57A | 5ersA-5ur0A:undetectable | 5ersA-5ur0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v8c | TRANSCRIPTIONALREGULATOR (Actinomycesoris) |
no annotation | 3 | THR A 166ALA A 177ASN A 173 | None | 0.60A | 5ersA-5v8cA:undetectable | 5ersA-5v8cA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vmt | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Neisseriagonorrhoeae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | THR A 153ALA A 149ASN A 154 | None | 0.59A | 5ersA-5vmtA:undetectable | 5ersA-5vmtA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y37 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Streptococcusagalactiae) |
no annotation | 3 | THR A 158ALA A 154ASN A 159 | None | 0.57A | 5ersA-5y37A:3.3 | 5ersA-5y37A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0f | RIBOSOME PRODUCTIONFACTOR 1 (Saccharomycescerevisiae) |
no annotation | 3 | THR I 99ALA I 103ASN I 100 | None | 0.30A | 5ersA-6c0fI:undetectable | 5ersA-6c0fI:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfz | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Acroporamillepora) |
no annotation | 3 | THR A 153ALA A 149ASN A 154 | None | 0.63A | 5ersA-6dfzA:3.8 | 5ersA-6dfzA:undetectable |