SIMILAR PATTERNS OF AMINO ACIDS FOR 5ERS_A_ACTA803

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1buc BUTYRYL-COA
DEHYDROGENASE


(Megasphaera
elsdenii)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 162
ALA A  92
ASN A 163
CAA  A 384 ( 3.8A)
CAA  A 384 ( 4.2A)
None
0.40A 5ersA-1bucA:
undetectable
5ersA-1bucA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Geobacillus
stearothermophilus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 151
ALA O 147
ASN O 152
None
0.60A 5ersA-1dbvO:
undetectable
5ersA-1dbvO:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3d [NIFE] HYDROGENASE
SMALL SUBUNIT
[NIFE] HYDROGENASE
LARGE SUBUNIT


(Desulfovibrio
desulfuricans;
Desulfovibrio
desulfuricans)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
PF00374
(NiFeSe_Hases)
3 THR B 177
ALA A  59
ASN B 178
None
0.56A 5ersA-1e3dB:
undetectable
5ersA-1e3dB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE


(Escherichia
coli)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 151
ALA O 147
ASN O 152
None
0.60A 5ersA-1gaeO:
2.9
5ersA-1gaeO:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)


(Leishmania
mexicana)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 168
ALA A 164
ASN A 169
None
0.59A 5ersA-1gyqA:
2.6
5ersA-1gyqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hdg HOLO-D-GLYCERALDEHYD
E-3-PHOSPHATE
DEHYDROGENASE


(Thermotoga
maritima)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 151
ALA O 147
ASN O 152
None
0.55A 5ersA-1hdgO:
undetectable
5ersA-1hdgO:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hxj BETA-GLUCOSIDASE

(Zea mays)
PF00232
(Glyco_hydro_1)
3 THR A 400
ALA A 254
ASN A 326
None
0.62A 5ersA-1hxjA:
undetectable
5ersA-1hxjA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ivh ISOVALERYL-COA
DEHYDROGENASE


(Homo sapiens)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 168
ALA A  99
ASN A 169
FAD  A 399 (-4.0A)
FAD  A 399 ( 4.8A)
None
0.38A 5ersA-1ivhA:
undetectable
5ersA-1ivhA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A


(Spinacia
oleracea)
no annotation 3 THR O 151
ALA O 147
ASN O 152
None
0.62A 5ersA-1jn0O:
undetectable
5ersA-1jn0O:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Achromobacter
xylosoxidans)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 156
ALA O 152
ASN O 157
None
0.59A 5ersA-1obfO:
2.0
5ersA-1obfO:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pqu ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE


(Haemophilus
influenzae)
PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC)
3 THR A  79
ALA A 101
ASN A  80
None
0.60A 5ersA-1pquA:
2.6
5ersA-1pquA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus)
PF00028
(Cadherin)
3 THR A 273
ALA A 257
ASN A 278
NAG  A 803 (-2.6A)
None
None
0.34A 5ersA-1q5aA:
undetectable
5ersA-1q5aA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ry9 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAK


(Shigella
flexneri)
PF03519
(Invas_SpaK)
3 THR A  34
ALA A  42
ASN A  44
None
0.60A 5ersA-1ry9A:
undetectable
5ersA-1ry9A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1shz GUANINE
NUCLEOTIDE-BINDING
PROTEIN
GALPHA(13):GALPHA(I1
) CHIMERA


(Mus musculus;
Rattus
norvegicus)
PF00503
(G-alpha)
3 THR A  87
ALA A 199
ASN A  91
None
0.60A 5ersA-1shzA:
2.1
5ersA-1shzA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ska 3-PHYTASE A

(Aspergillus
fumigatus)
PF00328
(His_Phos_2)
3 THR A 297
ALA A 433
ASN A 298
None
0.63A 5ersA-1skaA:
undetectable
5ersA-1skaA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6p PHENYLALANINE
AMMONIA-LYASE


(Rhodotorula
toruloides)
PF00221
(Lyase_aromatic)
3 THR A 513
ALA A 282
ASN A 517
None
0.53A 5ersA-1t6pA:
undetectable
5ersA-1t6pA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 2


(Streptomyces
coelicolor)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
3 THR B 330
ALA B  12
ASN B  14
None
0.64A 5ersA-1tqyB:
undetectable
5ersA-1tqyB:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1um4 ANTIBODY 21H3 H
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
3 THR H  29
ALA H  25
ASN H  78
None
0.63A 5ersA-1um4H:
undetectable
5ersA-1um4H:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc2 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Thermus
thermophilus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 151
ALA A 147
ASN A 152
None
0.58A 5ersA-1vc2A:
2.1
5ersA-1vc2A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8c S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE


(Clostridium
acetobutylicum)
PF13649
(Methyltransf_25)
3 THR A  49
ALA A   8
ASN A  51
None
0.61A 5ersA-1y8cA:
undetectable
5ersA-1y8cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ywg GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Plasmodium
falciparum)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 155
ALA O 151
ASN O 156
None
0.54A 5ersA-1ywgO:
undetectable
5ersA-1ywgO:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zca G ALPHA I/12

(Mus musculus)
PF00503
(G-alpha)
3 THR A  94
ALA A 202
ASN A  98
None
0.48A 5ersA-1zcaA:
2.6
5ersA-1zcaA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2i GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Synechococcus
sp.)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 157
ALA A 153
ASN A 158
None
0.60A 5ersA-2d2iA:
undetectable
5ersA-2d2iA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ep7 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Aquifex
aeolicus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 154
ALA A 150
ASN A 155
None
0.62A 5ersA-2ep7A:
2.1
5ersA-2ep7A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hr7 INSULIN RECEPTOR

(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
3 THR A 461
ALA A 458
ASN A 462
GOL  A 597 (-3.0A)
GOL  A 597 (-3.6A)
None
0.52A 5ersA-2hr7A:
undetectable
5ersA-2hr7A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1


(Kluyveromyces
marxianus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 151
ALA O 147
ASN O 152
None
0.55A 5ersA-2i5pO:
2.3
5ersA-2i5pO:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr4 PEPTIDASE M3B,
OLIGOENDOPEPTIDASE F


(Enterococcus
faecium)
PF01432
(Peptidase_M3)
PF08439
(Peptidase_M3_N)
3 THR A 423
ALA A 534
ASN A 427
None
0.54A 5ersA-2qr4A:
undetectable
5ersA-2qr4A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E


(Penicillium
citrinum)
PF01532
(Glyco_hydro_47)
3 THR A1193
ALA A1256
ASN A1249
None
0.51A 5ersA-2ri8A:
undetectable
5ersA-2ri8A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0n GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL


(Trypanosoma
brucei)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 167
ALA A 163
ASN A 168
None
0.64A 5ersA-2x0nA:
undetectable
5ersA-2x0nA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)


(Synechococcus
elongatus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 157
ALA A 153
ASN A 158
None
0.56A 5ersA-3b20A:
undetectable
5ersA-3b20A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cps GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Cryptosporidium
parvum)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 170
ALA A 166
ASN A 171
None
0.58A 5ersA-3cpsA:
4.1
5ersA-3cpsA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT


(Mus musculus)
PF00503
(G-alpha)
3 THR A  87
ALA A 199
ASN A  91
None
0.58A 5ersA-3cx6A:
3.3
5ersA-3cx6A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3doc GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Brucella
abortus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 155
ALA A 151
ASN A 156
None
0.61A 5ersA-3docA:
undetectable
5ersA-3docA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e6a GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
CYTOSOLIC


(Oryza sativa)
no annotation 3 THR O 156
ALA O 152
ASN O 157
SO4  O6921 (-4.8A)
None
None
0.62A 5ersA-3e6aO:
undetectable
5ersA-3e6aO:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ezy DEHYDROGENASE

(Thermotoga
maritima)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
3 THR A 289
ALA A 301
ASN A 293
None
0.63A 5ersA-3ezyA:
2.9
5ersA-3ezyA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3faj PUTATIVE
UNCHARACTERIZED
PROTEIN


(Acidianus
two-tailed
virus)
no annotation 3 THR A 107
ALA A  12
ASN A 111
None
None
CL  A 132 (-4.3A)
0.53A 5ersA-3fajA:
undetectable
5ersA-3fajA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnq GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE, TYPE
I


(Burkholderia
pseudomallei)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 156
ALA A 152
ASN A 157
None
0.58A 5ersA-3gnqA:
undetectable
5ersA-3gnqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ham AMINOGLYCOSIDE
PHOSPHOTRANSFERASE


(Enterococcus
faecium)
PF01636
(APH)
3 THR A 170
ALA A 294
ASN A 174
None
0.57A 5ersA-3hamA:
undetectable
5ersA-3hamA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hja GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Borreliella
burgdorferi)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 155
ALA A 151
ASN A 156
None
0.54A 5ersA-3hjaA:
2.2
5ersA-3hjaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C)
PF06016
(Reovirus_L2)
3 THR W 435
ALA W 804
ASN W1009
None
0.57A 5ersA-3iylW:
2.4
5ersA-3iylW:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2b GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A, CHLOROPLASTIC


(Arabidopsis
thaliana)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 151
ALA A 147
ASN A 152
None
0.58A 5ersA-3k2bA:
2.1
5ersA-3k2bA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksd GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1


(Staphylococcus
aureus)
no annotation 3 THR Q 153
ALA Q 149
ASN Q 154
None
0.61A 5ersA-3ksdQ:
undetectable
5ersA-3ksdQ:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Bartonella
henselae)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 155
ALA A 151
ASN A 156
None
0.58A 5ersA-3l0dA:
undetectable
5ersA-3l0dA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mde MEDIUM CHAIN
ACYL-COA
DEHYDROGENASE


(Sus scrofa)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 168
ALA A 100
ASN A 169
FAD  A 399 (-4.0A)
CO8  A 400 ( 4.2A)
None
0.43A 5ersA-3mdeA:
undetectable
5ersA-3mdeA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkh NITROALKANE OXIDASE

(Podospora
anserina)
PF00441
(Acyl-CoA_dh_1)
PF02771
(Acyl-CoA_dh_N)
3 THR A 172
ALA A  98
ASN A 173
FAD  A 500 (-3.9A)
FAD  A 500 ( 4.9A)
None
0.43A 5ersA-3mkhA:
undetectable
5ersA-3mkhA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5l BINDING PROTEIN
COMPONENT OF ABC
PHOSPHONATE
TRANSPORTER


(Pseudomonas
aeruginosa)
PF12974
(Phosphonate-bd)
3 THR A 291
ALA A 163
ASN A 295
None
EDO  A 411 (-3.9A)
EDO  A 411 (-3.7A)
0.60A 5ersA-3n5lA:
2.7
5ersA-3n5lA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3otn SUSD SUPERFAMILY
PROTEIN


(Parabacteroides
distasonis)
PF07980
(SusD_RagB)
PF14322
(SusD-like_3)
3 THR A 425
ALA A 429
ASN A 426
None
0.50A 5ersA-3otnA:
undetectable
5ersA-3otnA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owa ACYL-COA
DEHYDROGENASE


(Bacillus
anthracis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 185
ALA A 114
ASN A 186
FAD  A 601 (-3.9A)
None
None
0.34A 5ersA-3owaA:
undetectable
5ersA-3owaA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pym GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
3


(Saccharomyces
cerevisiae)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 152
ALA A 148
ASN A 153
None
0.57A 5ersA-3pymA:
2.2
5ersA-3pymA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4u PHND, SUBUNIT OF
ALKYLPHOSPHONATE ABC
TRANSPORTER


(Escherichia
coli)
PF12974
(Phosphonate-bd)
3 THR A 159
ALA A 155
ASN A 160
None
0.62A 5ersA-3s4uA:
2.2
5ersA-3s4uA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s83 GGDEF FAMILY PROTEIN

(Caulobacter
vibrioides)
PF00563
(EAL)
3 THR A 402
ALA A 363
ASN A 406
None
0.54A 5ersA-3s83A:
undetectable
5ersA-3s83A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sth GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Toxoplasma
gondii)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 154
ALA A 150
ASN A 155
None
0.57A 5ersA-3sthA:
2.5
5ersA-3sthA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN


(Sinorhizobium
meliloti)
PF08534
(Redoxin)
3 THR A  48
ALA A 149
ASN A  52
None
0.61A 5ersA-3umaA:
undetectable
5ersA-3umaA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdf GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Thermosynechococcus
elongatus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 156
ALA A 152
ASN A 157
None
0.53A 5ersA-3zdfA:
undetectable
5ersA-3zdfA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a01 PROTON
PYROPHOSPHATASE


(Vigna radiata)
PF03030
(H_PPase)
3 THR A 426
ALA A 538
ASN A 685
None
0.58A 5ersA-4a01A:
undetectable
5ersA-4a01A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akk NITRATE REGULATORY
PROTEIN


(Klebsiella
oxytoca)
PF03861
(ANTAR)
PF08376
(NIT)
3 THR A 129
ALA A 177
ASN A  54
None
EDO  A1392 (-3.3A)
EDO  A1392 (-4.2A)
0.59A 5ersA-4akkA:
undetectable
5ersA-4akkA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE


(Bacillus
anthracis)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 153
ALA A 149
ASN A 154
None
0.56A 5ersA-4dibA:
2.2
5ersA-4dibA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edp ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN


(Clostridium
perfringens)
PF13416
(SBP_bac_8)
3 THR A 263
ALA A  94
ASN A 265
None
0.50A 5ersA-4edpA:
undetectable
5ersA-4edpA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjf GGDEF FAMILY PROTEIN

(Caulobacter
vibrioides)
PF00563
(EAL)
3 THR A 402
ALA A 363
ASN A 406
None
0.58A 5ersA-4hjfA:
undetectable
5ersA-4hjfA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irn PROLYL-ACP
DEHYDROGENASE


([Oscillatoria]
sp. PCC 6506)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 160
ALA A  91
ASN A 161
FAD  A 400 (-3.9A)
None
None
0.48A 5ersA-4irnA:
undetectable
5ersA-4irnA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9d GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Brugia malayi)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 159
ALA A 155
ASN A 160
None
0.56A 5ersA-4k9dA:
2.0
5ersA-4k9dA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC


(Solanum
lycopersicum)
PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N)
3 THR A 515
ALA A 428
ASN A 514
None
SO4  A 603 (-4.0A)
None
0.53A 5ersA-4ksiA:
1.9
5ersA-4ksiA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kto ISOVALERYL-COA
DEHYDROGENASE


(Sinorhizobium
meliloti)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 163
ALA A  94
ASN A 164
FAD  A 401 (-4.0A)
None
None
0.34A 5ersA-4ktoA:
undetectable
5ersA-4ktoA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1f ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN


(Acidaminococcus
fermentans)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 158
ALA A  89
ASN A 159
FAD  A 401 (-3.9A)
None
None
0.34A 5ersA-4l1fA:
undetectable
5ersA-4l1fA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lsm GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE,
CYTOSOLIC


(Trypanosoma
cruzi)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 158
ALA A 154
ASN A 159
None
0.55A 5ersA-4lsmA:
3.6
5ersA-4lsmA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o59 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Bos taurus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 151
ALA O 147
ASN O 152
None
0.54A 5ersA-4o59O:
4.3
5ersA-4o59O:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5m ISOVALERYL-COA
DEHYDROGENASE


(Brucella suis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 THR A 158
ALA A  89
ASN A 159
None
0.35A 5ersA-4o5mA:
undetectable
5ersA-4o5mA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p8r GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE,
CYTOSOLIC


(Trypanosoma
brucei)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 152
ALA A 148
ASN A 153
None
0.57A 5ersA-4p8rA:
undetectable
5ersA-4p8rA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qqr 3,5-EPIMERASE/4-REDU
CTASE


(Arabidopsis
thaliana)
PF04321
(RmlD_sub_bind)
3 THR A 163
ALA A 112
ASN A 110
None
0.64A 5ersA-4qqrA:
3.0
5ersA-4qqrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rdq BESTROPHIN-1

(Gallus gallus)
PF01062
(Bestrophin)
3 THR A 307
ALA A 146
ASN A 308
GOL  A 501 (-4.8A)
GOL  A 501 (-3.2A)
GOL  A 501 (-4.6A)
0.57A 5ersA-4rdqA:
undetectable
5ersA-4rdqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr2 SUBTILISIN-LIKE 1
SERINE PROTEASE


(Plasmodium
vivax)
PF00082
(Peptidase_S8)
3 THR A 531
ALA A  73
ASN A 532
None
0.49A 5ersA-4tr2A:
4.2
5ersA-4tr2A:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4u90 GEPHYRIN

(Rattus
norvegicus)
PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C)
3 THR A 342
ALA A 356
ASN A 496
None
0.11A 5ersA-4u90A:
51.1
5ersA-4u90A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE LARGE
SUBUNIT
PERIPLASMIC [NIFE]
HYDROGENASE SMALL
SUBUNIT


(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris)
PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
3 THR L 187
ALA S  59
ASN L 188
None
0.57A 5ersA-4u9iL:
undetectable
5ersA-4u9iL:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x90 GROUP XV
PHOSPHOLIPASE A2


(Homo sapiens)
PF02450
(LCAT)
3 THR A 281
ALA A 133
ASN A 135
None
0.36A 5ersA-4x90A:
1.6
5ersA-4x90A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xee NEUROTENSIN RECEPTOR
TYPE 1, ENDOLYSIN
CHIMERA


(Rattus
norvegicus;
Escherichia
virus T4)
PF00001
(7tm_1)
PF00959
(Phage_lysozyme)
3 THR A 265
ALA A1093
ASN A1002
None
0.55A 5ersA-4xeeA:
undetectable
5ersA-4xeeA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxb INSULIN RECEPTOR

(Homo sapiens)
PF00041
(fn3)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
3 THR E 461
ALA E 458
ASN E 462
None
0.50A 5ersA-4zxbE:
undetectable
5ersA-4zxbE:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ap9 LIPASE

(Thermomyces
lanuginosus)
PF01764
(Lipase_3)
PF03893
(Lipase3_N)
3 THR A 199
ALA A 257
ASN A 200
None
0.50A 5ersA-5ap9A:
undetectable
5ersA-5ap9A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3r IMP-18

(Pseudomonas
aeruginosa)
no annotation 3 THR A 120
ALA A 116
ASN A 121
None
0.61A 5ersA-5b3rA:
undetectable
5ersA-5b3rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC


(Mus musculus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 258
ALA O 254
ASN O 259
None
0.55A 5ersA-5c7iO:
undetectable
5ersA-5c7iO:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC


(Homo sapiens)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR O 226
ALA O 222
ASN O 227
None
None
OCS  O 224 ( 4.8A)
0.55A 5ersA-5c7oO:
2.3
5ersA-5c7oO:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ch8 MONO- AND
DIACYLGLYCEROL
LIPASE


(Penicillium
cyclopium)
PF01764
(Lipase_3)
PF03893
(Lipase3_N)
3 THR A 197
ALA A 258
ASN A 198
CL  A 305 (-2.9A)
CL  A 305 ( 3.9A)
CL  A 305 ( 4.6A)
0.52A 5ersA-5ch8A:
undetectable
5ersA-5ch8A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9h ISOCITRATE LYASE

(Fusarium
graminearum)
PF00463
(ICL)
3 THR A 130
ALA A 116
ASN A 134
None
0.61A 5ersA-5e9hA:
undetectable
5ersA-5e9hA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyy CENTROLOBIUM
TOMENTOSUM LECTIN


(Centrolobium
tomentosum)
PF00139
(Lectin_legB)
3 THR A 116
ALA A 122
ASN A 119
None
NAG  A 301 ( 3.8A)
NAG  A 301 (-1.6A)
0.62A 5ersA-5eyyA:
undetectable
5ersA-5eyyA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN


(Lachnoclostridium
phytofermentans)
PF17167
(Glyco_hydro_36)
3 THR A 377
ALA A 625
ASN A 375
None
0.59A 5ersA-5h42A:
undetectable
5ersA-5h42A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im2 TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL


(Rhodoferax
ferrireducens)
PF03480
(DctP)
3 THR A 114
ALA A 118
ASN A 115
None
0.59A 5ersA-5im2A:
undetectable
5ersA-5im2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1


(Homo sapiens)
PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
3 THR A 316
ALA A 328
ASN A 320
None
0.63A 5ersA-5iy9A:
undetectable
5ersA-5iy9A:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jcf MELANOMA
DIFFERENTIATION
ASSOCIATED PROTEIN-5


(Gallus gallus)
PF00271
(Helicase_C)
PF04851
(ResIII)
PF11648
(RIG-I_C-RD)
3 THR A 785
ALA A 789
ASN A 786
G  X   6 ( 4.6A)
None
G  X   6 ( 4.1A)
0.41A 5ersA-5jcfA:
undetectable
5ersA-5jcfA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqv INSULIN
RECEPTOR,INSULIN
RECEPTOR


(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
3 THR E 461
ALA E 458
ASN E 462
None
0.50A 5ersA-5kqvE:
undetectable
5ersA-5kqvE:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ld5 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Atopobium
vaginae)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 170
ALA A 166
ASN A 171
None
0.57A 5ersA-5ld5A:
2.4
5ersA-5ld5A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmd METALLO-BETA-LACTAMA
SE 1


(Acinetobacter
baumannii)
PF00753
(Lactamase_B)
3 THR E 142
ALA E 138
ASN E 143
None
0.59A 5ersA-5mmdE:
undetectable
5ersA-5mmdE:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol2 ACYL-COA
DEHYDROGENASE


(Clostridioides
difficile)
no annotation 3 THR C 157
ALA C  88
ASN C 158
FAD  C 401 (-3.7A)
None
None
0.40A 5ersA-5ol2C:
undetectable
5ersA-5ol2C:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olj DIPEPTIDYL PEPTIDASE
IV


(Porphyromonas
gingivalis)
PF00326
(Peptidase_S9)
PF00930
(DPPIV_N)
3 THR A 441
ALA A  38
ASN A 460
None
0.59A 5ersA-5oljA:
3.0
5ersA-5oljA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u38 LECTIN

(Platypodium
elegans)
PF00139
(Lectin_legB)
3 THR A 116
ALA A 122
ASN A 119
None
NAG  A 301 (-3.5A)
NAG  A 301 (-1.8A)
0.60A 5ersA-5u38A:
undetectable
5ersA-5u38A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uld TRANSPORTER, NADC
FAMILY


(Vibrio cholerae)
PF00939
(Na_sulph_symp)
3 THR A 421
ALA A 414
ASN A 424
CIT  A 503 (-3.1A)
NA  A 502 ( 3.9A)
None
0.55A 5ersA-5uldA:
undetectable
5ersA-5uldA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ur0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Naegleria
gruberi)
no annotation 3 THR A 151
ALA A 147
ASN A 152
None
0.57A 5ersA-5ur0A:
undetectable
5ersA-5ur0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8c TRANSCRIPTIONAL
REGULATOR


(Actinomyces
oris)
no annotation 3 THR A 166
ALA A 177
ASN A 173
None
0.60A 5ersA-5v8cA:
undetectable
5ersA-5v8cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Neisseria
gonorrhoeae)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
3 THR A 153
ALA A 149
ASN A 154
None
0.59A 5ersA-5vmtA:
undetectable
5ersA-5vmtA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y37 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Streptococcus
agalactiae)
no annotation 3 THR A 158
ALA A 154
ASN A 159
None
0.57A 5ersA-5y37A:
3.3
5ersA-5y37A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0f RIBOSOME PRODUCTION
FACTOR 1


(Saccharomyces
cerevisiae)
no annotation 3 THR I  99
ALA I 103
ASN I 100
None
0.30A 5ersA-6c0fI:
undetectable
5ersA-6c0fI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dfz GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Acropora
millepora)
no annotation 3 THR A 153
ALA A 149
ASN A 154
None
0.63A 5ersA-6dfzA:
3.8
5ersA-6dfzA:
undetectable