SIMILAR PATTERNS OF AMINO ACIDS FOR 5EB3_A_UEGA202_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bt2 PROTEIN (CATECHOL
OXIDASE)

(Ipomoea batatas) 		PF00264
(Tyrosinase)
PF12142
(PPO1_DWL) 		4 LEU A 164
ILE A 268
PRO A 141
LEU A 129
 None
 1.24A 5eb3A-1bt2A:
undetectable		 5eb3A-1bt2A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 LEU A1136
ILE A1158
PRO A1169
LEU A1165
 None
 1.04A 5eb3A-1jl5A:
undetectable		 5eb3A-1jl5A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnt OVOTRANSFERRIN

(Gallus gallus) 		PF00405
(Transferrin) 		4 LEU A  43
ILE A  46
PRO A  71
LEU A  69
 None
 1.01A 5eb3A-1nntA:
undetectable		 5eb3A-1nntA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q0u BSTDEAD

(Geobacillus
stearothermophilus) 		PF00270
(DEAD) 		4 LEU A 163
ILE A 168
PRO A 197
LEU A 199
 None
 0.94A 5eb3A-1q0uA:
2.4		 5eb3A-1q0uA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf6 THREONYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00587
(tRNA-synt_2b)
PF02824
(TGS)
PF03129
(HGTP_anticodon)
PF07973
(tRNA_SAD) 		4 LEU A  31
ILE A  27
PRO A   7
LEU A  57
 None
 1.13A 5eb3A-1qf6A:
undetectable		 5eb3A-1qf6A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s58 B19 PARVOVIRUS
CAPSID

(Primate
erythroparvovirus
1) 		PF00740
(Parvo_coat) 		4 LEU A 149
ILE A 460
PRO A  47
LEU A  45
 None
 1.24A 5eb3A-1s58A:
undetectable		 5eb3A-1s58A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smk MALATE
DEHYDROGENASE,
GLYOXYSOMAL

(Citrullus
lanatus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LEU A 144
ILE A 140
PRO A 119
LEU A 159
 None
 1.23A 5eb3A-1smkA:
4.0		 5eb3A-1smkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tke THREONYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF02824
(TGS)
PF07973
(tRNA_SAD) 		4 LEU A  31
ILE A  27
PRO A   7
LEU A  57
 None
 1.11A 5eb3A-1tkeA:
undetectable		 5eb3A-1tkeA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txz HYPOTHETICAL 32.1
KDA PROTEIN IN
ADH3-RCA1 INTERGENIC
REGION

(Saccharomyces
cerevisiae) 		PF14519
(Macro_2) 		4 LEU A 226
ILE A 222
PRO A 276
LEU A 274
 None
 1.09A 5eb3A-1txzA:
undetectable		 5eb3A-1txzA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ub7 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
SYNTHASE

(Thermus
thermophilus) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 LEU A 117
ILE A 114
PRO A 283
LEU A 286
 None
 0.92A 5eb3A-1ub7A:
undetectable		 5eb3A-1ub7A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us4 PUTATIVE GLUR0
LIGAND BINDING CORE

(Thermus
thermophilus) 		PF16868
(NMT1_3) 		4 LEU A 282
ILE A 278
PRO A  34
LEU A  76
 None
 1.19A 5eb3A-1us4A:
undetectable		 5eb3A-1us4A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zch HYPOTHETICAL
OXIDOREDUCTASE YCND

(Bacillus
subtilis) 		PF00881
(Nitroreductase) 		4 LEU A 240
ILE A 236
PRO A 157
LEU A 158
 None
 1.22A 5eb3A-1zchA:
undetectable		 5eb3A-1zchA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcm CALPAIN 1, LARGE
[CATALYTIC] SUBUNIT

(Homo sapiens) 		PF00648
(Peptidase_C2) 		4 LEU A 175
ILE A 170
PRO A  88
LEU A  92
 None
 0.84A 5eb3A-1zcmA:
undetectable		 5eb3A-1zcmA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iy8 PROTEIN PM0188

(Pasteurella
multocida) 		PF11477
(PM0188) 		4 LEU A 108
ILE A 106
PRO A 119
LEU A 121
 None
 1.22A 5eb3A-2iy8A:
undetectable		 5eb3A-2iy8A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0a BETA-1,3-N-ACETYLGLU
COSAMINYLTRANSFERASE
MANIC FRINGE

(Mus musculus) 		PF02434
(Fringe) 		4 LEU A 288
ILE A 286
PRO A 269
LEU A 308
 None
 1.23A 5eb3A-2j0aA:
undetectable		 5eb3A-2j0aA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jj4 ACETYLGLUTAMATE
KINASE

(Synechococcus
elongatus) 		PF00696
(AA_kinase) 		4 LEU A 235
ILE A 236
PRO A 230
LEU A 227
 None
 1.16A 5eb3A-2jj4A:
undetectable		 5eb3A-2jj4A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		4 LEU A 245
ILE A 243
PRO A 227
LEU A 254
 None
 1.22A 5eb3A-2m6kA:
undetectable		 5eb3A-2m6kA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkg SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
65 KDA REGULATORY
SUBUNIT A ALPHA
ISOFORM

(Homo sapiens) 		PF02985
(HEAT)
PF13646
(HEAT_2) 		4 LEU A 551
ILE A 547
PRO A 523
LEU A 526
 None
 0.99A 5eb3A-2pkgA:
undetectable		 5eb3A-2pkgA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmi CYCLIN-DEPENDENT
PROTEIN KINASE PHO85

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		4 LEU A  80
ILE A  54
PRO A  47
LEU A  40
 None
 1.25A 5eb3A-2pmiA:
undetectable		 5eb3A-2pmiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfv ISOCITRATE
DEHYDROGENASE [NADP]

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 LEU A 405
ILE A 409
PRO A  34
LEU A  36
 None
 1.15A 5eb3A-2qfvA:
undetectable		 5eb3A-2qfvA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qmx PREPHENATE
DEHYDRATASE

(Chlorobaculum
tepidum) 		PF00800
(PDT) 		4 LEU A  21
ILE A  18
PRO A  12
LEU A 153
 None
 1.16A 5eb3A-2qmxA:
undetectable		 5eb3A-2qmxA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 LEU A 516
ILE A 512
PRO A 505
LEU A 535
 None
 1.05A 5eb3A-2qzpA:
undetectable		 5eb3A-2qzpA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w38 SIALIDASE

(Pseudomonas
aeruginosa) 		PF13088
(BNR_2) 		4 LEU A 355
ILE A 438
PRO A 334
LEU A 271
 None
 1.24A 5eb3A-2w38A:
undetectable		 5eb3A-2w38A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yew CAPSID PROTEIN

(Barmah Forest
virus) 		PF00944
(Peptidase_S3) 		4 LEU A 221
ILE A 219
PRO A 129
LEU A 154
 None
 1.23A 5eb3A-2yewA:
undetectable		 5eb3A-2yewA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE

(Geobacillus
kaustophilus) 		PF01259
(SAICAR_synt) 		4 LEU A  58
ILE A 195
PRO A 197
LEU A 202
 None
 1.22A 5eb3A-2ywvA:
undetectable		 5eb3A-2ywvA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z02 PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Methanocaldococcus
jannaschii) 		PF01259
(SAICAR_synt) 		4 LEU A  63
ILE A 200
PRO A 202
LEU A 207
 None
 1.17A 5eb3A-2z02A:
undetectable		 5eb3A-2z02A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1q ACYL-COA
DEHYDROGENASE

(Thermus
thermophilus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LEU A 559
ILE A 512
PRO A 507
LEU A 505
 None
 1.19A 5eb3A-2z1qA:
undetectable		 5eb3A-2z1qA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4t BETA-GALACTOSIDE
ALPHA-2,6-SIALYLTRAN
SFERASE

(Photobacterium
sp. JT-ISH-224) 		PF11477
(PM0188) 		4 LEU A 180
ILE A 184
PRO A 211
LEU A 209
 None
 1.21A 5eb3A-2z4tA:
2.4		 5eb3A-2z4tA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2f DNA POLYMERASE

(Pyrococcus
furiosus) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 LEU A 195
ILE A 198
PRO A 239
LEU A 219
 None
 1.19A 5eb3A-3a2fA:
undetectable		 5eb3A-3a2fA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go4 PROTEIN OF UNKNOWN
FUNCTION DUF574

(Streptomyces
avermitilis) 		PF04672
(Methyltransf_19) 		4 LEU A 163
ILE A  84
PRO A 142
LEU A 146
 None
 1.12A 5eb3A-3go4A:
3.2		 5eb3A-3go4A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN

(Pseudomonas
protegens) 		PF13407
(Peripla_BP_4) 		4 LEU A 170
ILE A 182
PRO A 211
LEU A 207
 None
 1.19A 5eb3A-3h75A:
2.8		 5eb3A-3h75A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7v O-SUCCINYLBENZOATE
SYNTHASE

(Thermosynechococcus
elongatus) 		PF13378
(MR_MLE_C) 		4 LEU A 294
ILE A 108
PRO A 105
LEU A 306
 None
 1.20A 5eb3A-3h7vA:
undetectable		 5eb3A-3h7vA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hl1 FERRITIN LIKE
PROTEIN

(Caulobacter
vibrioides) 		PF12902
(Ferritin-like) 		4 LEU A 268
ILE A 303
PRO A  26
LEU A 106
 None
 1.17A 5eb3A-3hl1A:
undetectable		 5eb3A-3hl1A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icf SERINE/THREONINE-PRO
TEIN PHOSPHATASE T

(Saccharomyces
cerevisiae) 		PF00149
(Metallophos)
PF08321
(PPP5) 		4 LEU A 356
ILE A 430
PRO A 363
LEU A 391
 None
 1.19A 5eb3A-3icfA:
undetectable		 5eb3A-3icfA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0c E2 ENVELOPE
GLYCOPROTEIN

(Venezuelan
equine
encephalitis
virus) 		PF00943
(Alpha_E2_glycop) 		4 LEU B 412
ILE B 408
PRO B 399
LEU B 397
 None
 1.09A 5eb3A-3j0cB:
undetectable		 5eb3A-3j0cB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE

(Parabacteroides
distasonis) 		PF13483
(Lactamase_B_3) 		4 LEU A 228
ILE A 233
PRO A 213
LEU A 186
 None
 1.15A 5eb3A-3kl7A:
undetectable		 5eb3A-3kl7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kre PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Ehrlichia
chaffeensis) 		PF01259
(SAICAR_synt) 		4 LEU A  57
ILE A 197
PRO A 199
LEU A 204
 None
 1.20A 5eb3A-3kreA:
undetectable		 5eb3A-3kreA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lfr PUTATIVE METAL ION
TRANSPORTER

(Pseudomonas
syringae group
genomosp. 3) 		PF00571
(CBS) 		4 LEU A 111
ILE A  76
PRO A  82
LEU A  86
 None
 1.20A 5eb3A-3lfrA:
undetectable		 5eb3A-3lfrA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN

(Rhodobacter
capsulatus) 		PF00590
(TP_methylase) 		4 LEU A  93
ILE A  96
PRO A 133
LEU A 134
 None
 1.24A 5eb3A-3nd1A:
undetectable		 5eb3A-3nd1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvj ALPHA-KETOGLUTARATE-
DEPENDENT TAURINE
DIOXYGENASE

(Pseudomonas
putida) 		PF02668
(TauD) 		4 LEU A  43
ILE A  16
PRO A   7
LEU A   8
 None
 1.20A 5eb3A-3pvjA:
undetectable		 5eb3A-3pvjA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q1n GALACTOSE MUTAROTASE
RELATED ENZYME

(Lactobacillus
paracasei) 		PF01263
(Aldose_epim) 		4 LEU A 169
ILE A 187
PRO A 196
LEU A 160
 None
 1.12A 5eb3A-3q1nA:
undetectable		 5eb3A-3q1nA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q1n GALACTOSE MUTAROTASE
RELATED ENZYME

(Lactobacillus
paracasei) 		PF01263
(Aldose_epim) 		4 LEU A 169
ILE A 187
PRO A 196
LEU A 197
 None
 1.23A 5eb3A-3q1nA:
undetectable		 5eb3A-3q1nA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbd 3-DEHYDROQUINATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF01761
(DHQ_synthase) 		4 LEU A 335
ILE A 193
PRO A 196
LEU A 199
 None
 1.24A 5eb3A-3qbdA:
4.3		 5eb3A-3qbdA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tk3 CYTOCHROME P450 2B4

(Oryctolagus
cuniculus) 		PF00067
(p450) 		4 LEU A 431
ILE A 435
PRO A 428
LEU A 392
 None
 1.15A 5eb3A-3tk3A:
undetectable		 5eb3A-3tk3A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uog ALCOHOL
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 121
ILE A 338
PRO A 322
LEU A 325
 None
 1.17A 5eb3A-3uogA:
3.4		 5eb3A-3uogA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8d CHOLESTEROL
7-ALPHA-MONOOXYGENAS
E

(Homo sapiens) 		PF00067
(p450) 		4 LEU A  71
ILE A  39
PRO A  52
LEU A  56
 None
 0.88A 5eb3A-3v8dA:
undetectable		 5eb3A-3v8dA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w53 BETA-GLUCOSIDASE

(Micrococcus
antarcticus) 		PF00232
(Glyco_hydro_1) 		4 LEU A 224
ILE A 222
PRO A 257
LEU A 259
 None
 1.09A 5eb3A-3w53A:
undetectable		 5eb3A-3w53A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfo POLY A POLYMERASE

(Aquifex
aeolicus) 		PF01743
(PolyA_pol)
PF01966
(HD)
PF12627
(PolyA_pol_RNAbd) 		4 LEU A 360
ILE A 356
PRO A 254
LEU A 249
 None
 0.96A 5eb3A-3wfoA:
undetectable		 5eb3A-3wfoA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfp POLY A POLYMERASE

(Aquifex
aeolicus;
synthetic
construct) 		PF01743
(PolyA_pol)
PF01966
(HD)
PF12627
(PolyA_pol_RNAbd) 		4 LEU A 360
ILE A 356
PRO A 254
LEU A 249
 None
 0.96A 5eb3A-3wfpA:
undetectable		 5eb3A-3wfpA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zjk BETA GLYCOSIDASE

(Thermus
thermophilus) 		PF00232
(Glyco_hydro_1) 		4 LEU A 218
ILE A 216
PRO A 245
LEU A 247
 CL  A1430 ( 4.0A)
None
None
None
 1.07A 5eb3A-3zjkA:
undetectable		 5eb3A-3zjkA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dll 2-HYDROXY-3-OXOPROPI
ONATE REDUCTASE

(Polaromonas sp.
JS666) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 LEU A 119
ILE A  90
PRO A 178
LEU A 180
 None
 0.97A 5eb3A-4dllA:
4.9		 5eb3A-4dllA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
subtilis) 		PF02350
(Epimerase_2) 		4 LEU A 265
ILE A 262
PRO A 191
LEU A 193
 UDP  A 402 (-4.5A)
None
None
None
 0.97A 5eb3A-4fkzA:
3.6		 5eb3A-4fkzA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gve NUCLEOPROTEIN

(Tacaribe
mammarenavirus) 		PF17290
(Arena_ncap_C) 		4 LEU A 399
ILE A 383
PRO A 451
LEU A 476
 None
 1.17A 5eb3A-4gveA:
undetectable		 5eb3A-4gveA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz2 SUPEROXIDE DISMUTASE

(Clostridioides
difficile) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 LEU A 162
ILE A 190
PRO A 125
LEU A 129
 None
 1.21A 5eb3A-4jz2A:
undetectable		 5eb3A-4jz2A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0e HEAVY METAL CATION
TRICOMPONENT EFFLUX
PUMP ZNEA(CZCA-LIKE)

(Cupriavidus
metallidurans) 		PF00873
(ACR_tran) 		4 LEU A 311
ILE A 310
PRO A 162
LEU A 164
 None
 0.94A 5eb3A-4k0eA:
undetectable		 5eb3A-4k0eA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l22 PHOSPHORYLASE

(Streptococcus
mutans) 		PF00343
(Phosphorylase) 		4 LEU A 159
ILE A 153
PRO A  99
LEU A 101
 None
 1.12A 5eb3A-4l22A:
3.2		 5eb3A-4l22A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lac PP2A SCAFFOLD
SUBUNIT A,
TRUNCATED, AN
INTERNAL DELETION OF
PP2A A

(Homo sapiens) 		PF02985
(HEAT)
PF13646
(HEAT_2) 		4 LEU A 551
ILE A 547
PRO A 523
LEU A 526
 None
 1.18A 5eb3A-4lacA:
undetectable		 5eb3A-4lacA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n03 ABC-TYPE
BRANCHED-CHAIN AMINO
ACID TRANSPORT
SYSTEMS PERIPLASMIC
COMPONENT-LIKE
PROTEIN

(Thermomonospora
curvata) 		PF13458
(Peripla_BP_6) 		4 LEU A 125
ILE A  71
PRO A  66
LEU A  60
 PLM  A 601 ( 4.3A)
None
None
None
 1.23A 5eb3A-4n03A:
7.7		 5eb3A-4n03A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Chromohalobacter
salexigens) 		PF03480
(DctP) 		4 LEU A 319
ILE A 316
PRO A 112
LEU A 114
 None
 0.81A 5eb3A-4n8gA:
undetectable		 5eb3A-4n8gA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nj8 ANKYRIN REPEAT AND
SAM
DOMAIN-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF00536
(SAM_1) 		4 LEU A  15
ILE A  18
PRO A  55
LEU A  45
 None
 1.00A 5eb3A-4nj8A:
undetectable		 5eb3A-4nj8A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ope NRPS/PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A4543
ILE A4508
PRO A4519
LEU A4522
 None
 1.25A 5eb3A-4opeA:
undetectable		 5eb3A-4opeA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oua LATENT FORM OF PPO4
TYROSINASE

(Agaricus
bisporus) 		PF00264
(Tyrosinase) 		4 LEU B 205
ILE B 206
PRO B 140
LEU B 138
 None
 0.88A 5eb3A-4ouaB:
undetectable		 5eb3A-4ouaB:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oua PROTEOLYTICALLY
ACTIVATED FORM OF
PPO4 TYROSINASE

(Agaricus
bisporus) 		PF00264
(Tyrosinase) 		4 LEU A 205
ILE A 206
PRO A 140
LEU A 138
 None
 0.92A 5eb3A-4ouaA:
undetectable		 5eb3A-4ouaA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8f RIBOKINASE

(Vibrio cholerae) 		PF00294
(PfkB) 		4 LEU A 209
ILE A 214
PRO A 164
LEU A 170
 None
 1.13A 5eb3A-4x8fA:
2.5		 5eb3A-4x8fA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9e DEOXYGUANOSINETRIPHO
SPHATE
TRIPHOSPHOHYDROLASE

(Escherichia
coli) 		PF01966
(HD) 		4 LEU A 172
ILE A 176
PRO A 470
LEU A 462
 None
 1.10A 5eb3A-4x9eA:
undetectable		 5eb3A-4x9eA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xz3 ACYL-COA SYNTHETASE
(NDP FORMING)

(Candidatus
Korarchaeum
cryptofilum) 		PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig) 		4 LEU A 447
ILE A 295
PRO A 235
LEU A 275
 None
 1.13A 5eb3A-4xz3A:
3.9		 5eb3A-4xz3A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhc STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomyces
pombe) 		no annotation 4 LEU A1013
ILE A 587
PRO A 589
LEU A1039
 None
 1.11A 5eb3A-4yhcA:
undetectable		 5eb3A-4yhcA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE

(Pseudomonas
aeruginosa) 		PF01113
(DapB_N)
PF05173
(DapB_C) 		4 LEU A 111
ILE A  98
PRO A  79
LEU A  83
 None
 1.21A 5eb3A-4ywjA:
4.5		 5eb3A-4ywjA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0c TOLL-LIKE RECEPTOR
13

(Mus musculus) 		PF00560
(LRR_1)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 571
ILE A 576
PRO A 588
LEU A 559
 None
 1.08A 5eb3A-4z0cA:
undetectable		 5eb3A-4z0cA:
11.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zhy YFIR

(Pseudomonas
aeruginosa) 		PF13689
(DUF4154) 		4 LEU A 166
ILE A 169
PRO A 178
LEU A 181
 None
 0.64A 5eb3A-4zhyA:
30.4		 5eb3A-4zhyA:
82.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah0 LIPASE

(Pelosinus
fermentans) 		no annotation 4 LEU A 183
ILE A 309
PRO A 304
LEU A 302
 None
 1.02A 5eb3A-5ah0A:
undetectable		 5eb3A-5ah0A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cww NUCLEOPORIN NUP82

(Chaetomium
thermophilum) 		no annotation 4 LEU B 302
ILE B 299
PRO B 295
LEU B 183
 None
 1.13A 5eb3A-5cwwB:
undetectable		 5eb3A-5cwwB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czd ACYL-CARRIER-PROTEIN

(Streptomyces
halstedii) 		PF00550
(PP-binding) 		4 LEU B  17
ILE B  32
PRO B  67
LEU B  10
 None
 1.19A 5eb3A-5czdB:
undetectable		 5eb3A-5czdB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dsd NUCLEOPROTEIN

(Bundibugyo
ebolavirus) 		PF05505
(Ebola_NP) 		4 LEU A 666
ILE A 665
PRO A 689
LEU A 692
 None
 1.07A 5eb3A-5dsdA:
undetectable		 5eb3A-5dsdA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2x NP

(Tai Forest
ebolavirus) 		PF05505
(Ebola_NP) 		4 LEU A 666
ILE A 665
PRO A 689
LEU A 692
 None
 1.06A 5eb3A-5e2xA:
undetectable		 5eb3A-5e2xA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eb2 YFIR

(Pseudomonas
aeruginosa) 		PF13689
(DUF4154) 		4 LEU A 166
ILE A 169
PRO A 178
LEU A 181
 None
TRP  A 201 ( 4.3A)
TRP  A 201 (-4.0A)
None
 0.18A 5eb3A-5eb2A:
32.1		 5eb3A-5eb2A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exr DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
PF08996
(zf-DNA_Pol) 		4 LEU C 537
ILE C 633
PRO C 763
LEU C 766
 None
 1.21A 5eb3A-5exrC:
undetectable		 5eb3A-5exrC:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		4 LEU A 406
ILE A 422
PRO A 493
LEU A 530
 None
 1.20A 5eb3A-5gggA:
undetectable		 5eb3A-5gggA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2v IMPORTIN SUBUNIT
BETA-3

(Saccharomyces
cerevisiae) 		PF13513
(HEAT_EZ) 		4 LEU A 410
ILE A 414
PRO A 453
LEU A 455
 None
 1.00A 5eb3A-5h2vA:
undetectable		 5eb3A-5h2vA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A

(Escherichia
coli;
Staphylococcus
aureus) 		PF00202
(Aminotran_3)
PF02216
(B) 		4 LEU A 298
ILE A 313
PRO A 138
LEU A 136
 None
 1.11A 5eb3A-5h7dA:
3.8		 5eb3A-5h7dA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ham RICKCE

(Rickettsia
bellii) 		no annotation 4 LEU A 567
ILE A 557
PRO A 598
LEU A 600
 None
 1.20A 5eb3A-5hamA:
undetectable		 5eb3A-5hamA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iud DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 LEU A 537
ILE A 633
PRO A 763
LEU A 766
 None
 1.14A 5eb3A-5iudA:
undetectable		 5eb3A-5iudA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l7l ELP3 FAMILY, ELP3
FAMILY

(Dehalococcoides
mccartyi) 		PF04055
(Radical_SAM)
PF16199
(Radical_SAM_C) 		4 LEU A 228
ILE A 275
PRO A 270
LEU A 268
 None
ZN  A 501 (-3.8A)
None
None
 0.87A 5eb3A-5l7lA:
undetectable		 5eb3A-5l7lA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxz SECRETED PROTEIN

(Streptomyces
lividans) 		PF07646
(Kelch_2)
PF09118
(DUF1929) 		4 LEU B 619
ILE B 598
PRO B 400
LEU B 397
 None
 1.18A 5eb3A-5lxzB:
undetectable		 5eb3A-5lxzB:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mp2 TYPE II SECRETION
SYSTEM PROTEIN D

(Pseudomonas
aeruginosa) 		no annotation 4 LEU A 255
ILE A 244
PRO A 161
LEU A 159
 None
 0.95A 5eb3A-5mp2A:
undetectable		 5eb3A-5mp2A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mze 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Mus musculus) 		no annotation 4 LEU A 108
ILE A 111
PRO A 125
LEU A 127
 None
 1.15A 5eb3A-5mzeA:
undetectable		 5eb3A-5mzeA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nux CHROMATE REDUCTASE

(Thermus
scotoductus) 		no annotation 4 LEU A 317
ILE A 297
PRO A 300
LEU A   4
 None
 0.89A 5eb3A-5nuxA:
undetectable		 5eb3A-5nuxA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc9 -

(-) 		no annotation 4 LEU A 161
ILE A 166
PRO A 144
LEU A 151
 None
 1.06A 5eb3A-5oc9A:
undetectable		 5eb3A-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogz -

(-) 		no annotation 4 LEU A 221
ILE A 219
PRO A 253
LEU A 255
 None
 1.17A 5eb3A-5ogzA:
undetectable		 5eb3A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		4 LEU T3391
ILE T3393
PRO T3355
LEU T3229
 None
 1.16A 5eb3A-5ojsT:
undetectable		 5eb3A-5ojsT:
3.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tbk IMPORTIN SUBUNIT
ALPHA-3

(Homo sapiens) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		4 LEU A 205
ILE A 208
PRO A 245
LEU A 247
 None
 1.19A 5eb3A-5tbkA:
undetectable		 5eb3A-5tbkA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vi6 HISTONE DEACETYLASE
8

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		4 LEU A 366
ILE A 362
PRO A 230
LEU A 200
 None
 1.04A 5eb3A-5vi6A:
undetectable		 5eb3A-5vi6A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 4 LEU A 431
ILE A 435
PRO A 428
LEU A 392
 None
 1.23A 5eb3A-5wbgA:
undetectable		 5eb3A-5wbgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wls POLLEN RECEPTOR-LIKE
KINASE 3

(Arabidopsis
thaliana) 		no annotation 4 LEU A 192
ILE A 207
PRO A 180
LEU A 199
 None
 1.22A 5eb3A-5wlsA:
undetectable		 5eb3A-5wlsA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 LEU A1011
ILE A1010
PRO A1105
LEU A1460
 None
 1.21A 5eb3A-5xsyA:
undetectable		 5eb3A-5xsyA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9w POLLEN RECEPTOR-LIKE
KINASE 6

(Arabidopsis
thaliana) 		no annotation 4 LEU B 197
ILE B 212
PRO B 185
LEU B 204
 None
 1.12A 5eb3A-5y9wB:
undetectable		 5eb3A-5y9wB:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6es9 ACYL-COA
DEHYDROGENASE

(Paracoccus
denitrificans) 		no annotation 4 LEU A 249
ILE A 205
PRO A 201
LEU A 199
 None
 1.21A 5eb3A-6es9A:
undetectable		 5eb3A-6es9A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190

(Arabidopsis
thaliana) 		no annotation 4 LEU B 120
ILE B 116
PRO B  89
LEU B 103
 None
 1.25A 5eb3A-6fg8B:
undetectable		 5eb3A-6fg8B:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190

(Arabidopsis
thaliana) 		no annotation 4 LEU B 120
ILE B 116
PRO B  89
LEU B 103
 None
 1.24A 5eb3A-6g3wB:
undetectable		 5eb3A-6g3wB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g9o VOLUME-REGULATED
ANION CHANNEL
SUBUNIT LRRC8A

(Mus musculus) 		no annotation 4 LEU A 596
ILE A 619
PRO A 607
LEU A 603
 None
 1.10A 5eb3A-6g9oA:
undetectable		 5eb3A-6g9oA:
17.61