SIMILAR PATTERNS OF AMINO ACIDS FOR 5EAJ_B_FOLB201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8g PROTEIN
(1-AMINOCYCLOPROPANE
-1-CARBOXYLATE
SYNTHASE)

(Malus domestica) 		PF00155
(Aminotran_1_2) 		3 ASP A  53
ARG A 416
ARG A 337
 None
 0.91A 5eajB-1b8gA:
1.6		 5eajB-1b8gA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cz3 DIHYDROFOLATE
REDUCTASE

(Thermotoga
maritima) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  53
ARG A  58
 None
 0.85A 5eajB-1cz3A:
20.1		 5eajB-1cz3A:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gtk PORPHOBILINOGEN
DEAMINASE

(Escherichia
coli) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		3 ASP A 106
ARG A 227
ARG A 260
 None
 0.89A 5eajB-1gtkA:
1.0		 5eajB-1gtkA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9x M32 CARBOXYPEPTIDASE

(Pyrococcus
furiosus) 		PF02074
(Peptidase_M32) 		3 ASP A 348
ARG A 303
ARG A 311
 None
 0.95A 5eajB-1k9xA:
0.0		 5eajB-1k9xA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lgy TRIACYLGLYCEROL
LIPASE

(Rhizopus niveus) 		PF01764
(Lipase_3) 		3 ASP A 243
ARG A 179
ARG A 198
 None
 0.95A 5eajB-1lgyA:
0.0		 5eajB-1lgyA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvp TATA BOX BINDING
PROTEIN
TRANSCRIPTION
INITIATION FACTOR
IIA GAMMA CHAIN

(Homo sapiens;
Homo sapiens) 		PF00352
(TBP)
PF02268
(TFIIA_gamma_N)
PF02751
(TFIIA_gamma_C) 		3 ASP D  78
ARG A 188
ARG A 205
 None
 0.79A 5eajB-1nvpD:
undetectable		 5eajB-1nvpD:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2

(Synechocystis
sp. PCC 6803) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		3 ASP A  37
ARG A 206
ARG A 205
 None
ONL  A2511 (-4.0A)
None
 0.98A 5eajB-1ofeA:
0.0		 5eajB-1ofeA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06969
(HemN_C) 		3 ASP A 209
ARG A 434
ARG A 308
 SAM  A 501 (-3.7A)
None
None
 0.99A 5eajB-1oltA:
0.0		 5eajB-1oltA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT

(Homo sapiens;
Mus musculus) 		PF13472
(Lipase_GDSL_2)
PF00400
(WD40) 		3 ASP A  41
ARG C 212
ARG C 238
 None
 0.58A 5eajB-1vyhA:
1.1		 5eajB-1vyhA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wru 43 KDA TAIL PROTEIN

(Escherichia
virus Mu) 		PF05954
(Phage_GPD) 		3 ASP A 131
ARG A 268
ARG A 336
 None
 0.85A 5eajB-1wruA:
undetectable		 5eajB-1wruA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 HYPOTHETICAL PROTEIN
PH1363
SARCOSINE OXIDASE

(Pyrococcus
horikoshii;
Pyrococcus
horikoshii) 		PF07992
(Pyr_redox_2)
PF13510
(Fer2_4)
PF01266
(DAO) 		3 ASP A 472
ARG B 302
ARG B  46
 None
FMN  A 802 (-4.0A)
FMN  A 802 ( 2.8A)
 0.98A 5eajB-1y56A:
undetectable		 5eajB-1y56A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yll CONSERVED
HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF05962
(HutD) 		3 ASP A  46
ARG A  61
ARG A  41
 None
 0.82A 5eajB-1yllA:
undetectable		 5eajB-1yllA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ys7 TRANSCRIPTIONAL
REGULATORY PROTEIN
PRRA

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		3 ASP A  53
ARG A 163
ARG A  74
 None
 0.96A 5eajB-1ys7A:
undetectable		 5eajB-1ys7A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 ASP B 157
ARG B 359
ARG B 353
 None
 0.98A 5eajB-2amcB:
undetectable		 5eajB-2amcB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cn3 BETA-1,4-XYLOGLUCAN
HYDROLASE

(Ruminiclostridium
thermocellum) 		PF02012
(BNR) 		3 ASP A 213
ARG A 158
ARG A 179
 None
XYS  A1773 ( 3.3A)
None
 0.97A 5eajB-2cn3A:
undetectable		 5eajB-2cn3A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwa SINGLE-STRAND
BINDING PROTEIN

(Thermus
thermophilus) 		PF00436
(SSB) 		3 ASP A 117
ARG A 212
ARG A  55
 None
 0.94A 5eajB-2cwaA:
undetectable		 5eajB-2cwaA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cx1 HYPOTHETICAL PROTEIN
APE0525

(Aeropyrum
pernix) 		PF01472
(PUA)
PF09183
(DUF1947) 		3 ASP A  72
ARG A 162
ARG A 166
 None
 0.95A 5eajB-2cx1A:
undetectable		 5eajB-2cx1A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1m L-GLUTAMATE OXIDASE
L-GLUTAMATE OXIDASE

(Streptomyces
sp. X-119-6;
Streptomyces
sp. X-119-6) 		PF01593
(Amino_oxidase)
PF01593
(Amino_oxidase) 		3 ASP B 453
ARG A 204
ARG A 191
 None
 0.97A 5eajB-2e1mB:
undetectable		 5eajB-2e1mB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hyt TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Pectobacterium
atrosepticum) 		PF00440
(TetR_N) 		3 ASP A  67
ARG A 133
ARG A  91
 None
None
EDO  A 197 (-4.0A)
 0.94A 5eajB-2hytA:
undetectable		 5eajB-2hytA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf4 PERIPLASMIC
TREHALASE

(Escherichia
coli) 		PF01204
(Trehalase) 		3 ASP A  65
ARG A 273
ARG A 205
 None
None
VDM  A1548 (-3.8A)
 0.98A 5eajB-2jf4A:
undetectable		 5eajB-2jf4A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l7b APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		3 ASP A 151
ARG A 274
ARG A 260
 None
 0.82A 5eajB-2l7bA:
undetectable		 5eajB-2l7bA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owo DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		3 ASP A 285
ARG A 305
ARG A 136
 None
 0.94A 5eajB-2owoA:
undetectable		 5eajB-2owoA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfq 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Escherichia
coli) 		PF00275
(EPSP_synthase) 		3 ASP A  48
ARG A 344
ARG A 124
 None
FMT  A 601 (-2.6A)
FMT  A 602 (-3.1A)
 0.95A 5eajB-2qfqA:
undetectable		 5eajB-2qfqA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8a LONG-CHAIN FATTY
ACID TRANSPORT
PROTEIN

(Escherichia
coli) 		PF03349
(Toluene_X) 		3 ASP A  26
ARG A 282
ARG A 222
 None
 0.87A 5eajB-2r8aA:
undetectable		 5eajB-2r8aA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uut RNA-DIRECTED RNA
POLYMERASE

(Sapporo virus) 		PF00680
(RdRP_1) 		3 ASP A 242
ARG A 409
ARG A 171
 None
 0.98A 5eajB-2uutA:
undetectable		 5eajB-2uutA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va8 SKI2-TYPE HELICASE

(Sulfolobus
solfataricus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ASP A 532
ARG A  78
ARG A 155
 None
SO4  A1706 (-3.6A)
SO4  A1706 (-2.9A)
 0.78A 5eajB-2va8A:
undetectable		 5eajB-2va8A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbk TYPE 2 DNA
TOPOISOMERASE 6
SUBUNIT B

(Sulfolobus
shibatae) 		PF02518
(HATPase_c)
PF09239
(Topo-VIb_trans) 		3 ASP B 386
ARG B 186
ARG B 193
 None
 0.73A 5eajB-2zbkB:
undetectable		 5eajB-2zbkB:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbz CYTOCHROME P450-SU1

(Streptomyces
griseolus) 		PF00067
(p450) 		3 ASP A 292
ARG A  73
ARG A 297
 None
VDX  A 501 ( 4.2A)
HEM  A 413 (-3.0A)
 0.99A 5eajB-2zbzA:
undetectable		 5eajB-2zbzA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zpa UNCHARACTERIZED
PROTEIN YPFI

(Escherichia
coli) 		PF05127
(Helicase_RecD)
PF08351
(DUF1726)
PF13718
(GNAT_acetyltr_2)
PF17176
(tRNA_bind_3) 		3 ASP A 125
ARG A 379
ARG A 460
 None
 0.98A 5eajB-2zpaA:
undetectable		 5eajB-2zpaA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bqw PUTATIVE CAPSID
PROTEIN OF PROPHAGE

(Escherichia
coli) 		PF03864
(Phage_cap_E) 		3 ASP A 106
ARG A 126
ARG A  19
 None
 0.75A 5eajB-3bqwA:
undetectable		 5eajB-3bqwA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3b CASEIN KINASE II
SUBUNIT ALPHA'

(Homo sapiens) 		PF00069
(Pkinase) 		3 ASP X 166
ARG X  44
ARG X  65
 None
CCK  X 351 (-4.6A)
None
 0.91A 5eajB-3e3bX:
undetectable		 5eajB-3e3bX:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8j COPROPORPHYRINOGEN
III OXIDASE

(Leishmania
naiffi) 		PF01218
(Coprogen_oxidas) 		3 ASP A 131
ARG A 250
ARG A 111
 None
 0.54A 5eajB-3e8jA:
undetectable		 5eajB-3e8jA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f8r THIOREDOXIN
REDUCTASE (TRXB-3)

(Sulfolobus
solfataricus) 		PF07992
(Pyr_redox_2) 		3 ASP A 264
ARG A 126
ARG A 296
 None
NAP  A4001 (-3.0A)
NAP  A4001 (-3.2A)
 0.82A 5eajB-3f8rA:
1.9		 5eajB-3f8rA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fid PUTATIVE OUTER
MEMBRANE PROTEIN
(LPXR)

(Salmonella
enterica) 		PF09982
(DUF2219) 		3 ASP A  32
ARG A 256
ARG A 226
 None
None
GOL  A 302 (-4.5A)
 0.84A 5eajB-3fidA:
undetectable		 5eajB-3fidA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyr PHENOXAZINONE
SYNTHASE

(Streptomyces
antibioticus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ASP A 371
ARG A 327
ARG A 378
 None
 0.96A 5eajB-3gyrA:
undetectable		 5eajB-3gyrA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA

(Moorella
thermoacetica) 		PF03598
(CdhC) 		3 ASP M 203
ARG M 649
ARG M 616
 None
 0.97A 5eajB-3i04M:
undetectable		 5eajB-3i04M:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jd5 28S RIBOSOMAL
PROTEIN S2,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S9,
MITOCHONDRIAL

(Bos taurus;
Bos taurus) 		PF00318
(Ribosomal_S2)
PF00380
(Ribosomal_S9) 		3 ASP I 143
ARG B 127
ARG B 253
 None
 0.97A 5eajB-3jd5I:
undetectable		 5eajB-3jd5I:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvs 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Vibrio cholerae) 		PF00275
(EPSP_synthase) 		3 ASP A  48
ARG A 345
ARG A 124
 None
GPJ  A 429 (-2.6A)
GPJ  A 429 (-3.0A)
 0.94A 5eajB-3nvsA:
undetectable		 5eajB-3nvsA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ny2 E3 UBIQUITIN-PROTEIN
LIGASE UBR2

(Homo sapiens) 		PF02207
(zf-UBR) 		3 ASP A 118
ARG A 137
ARG A 139
 None
 0.82A 5eajB-3ny2A:
undetectable		 5eajB-3ny2A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogk CORONATINE-INSENSITI
VE PROTEIN 1
JAZ1 INCOMPLETE
DEGRON PEPTIDE

(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		no annotation
PF09425
(CCT_2) 		3 ASP B 407
ARG B 121
ARG Q 206
 None
PO4  B1103 (-3.0A)
PO4  B1102 (-3.1A)
 0.68A 5eajB-3ogkB:
undetectable		 5eajB-3ogkB:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 HEAVY CHAIN
MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN

(Cricetulus
migratorius;
Cricetulus
migratorius) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		3 ASP L   1
ARG H  66
ARG H  38
 None
 0.93A 5eajB-3r08L:
undetectable		 5eajB-3r08L:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv6 ISOCHORISMATE
SYNTHASE/ISOCHORISMA
TE-PYRUVATE LYASE
MBTI

(Mycobacterium
tuberculosis) 		PF00425
(Chorismate_bind) 		3 ASP A 395
ARG A 149
ARG A 140
 None
 0.78A 5eajB-3rv6A:
undetectable		 5eajB-3rv6A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		3 ASP A 442
ARG A 205
ARG A 220
 None
 0.96A 5eajB-3sybA:
undetectable		 5eajB-3sybA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgl TRIACYL-GLYCEROL
ACYLHYDROLASE

(Rhizomucor
miehei) 		PF01764
(Lipase_3) 		3 ASP A 243
ARG A 178
ARG A 197
 None
 0.97A 5eajB-3tglA:
undetectable		 5eajB-3tglA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u24 PUTATIVE LIPOPROTEIN

(Shewanella
oneidensis) 		PF05960
(DUF885) 		3 ASP A 289
ARG A 466
ARG A 548
 ZN  A   5 (-2.2A)
None
None
 0.94A 5eajB-3u24A:
undetectable		 5eajB-3u24A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
pyogenes) 		PF09704
(Cas_Cas5d) 		3 ASP A 113
ARG A 125
ARG A 132
 None
 0.99A 5eajB-3vzhA:
undetectable		 5eajB-3vzhA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1g DNA LIGASE 4

(Homo sapiens) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		3 ASP A 210
ARG A  40
ARG A  47
 None
 0.74A 5eajB-3w1gA:
undetectable		 5eajB-3w1gA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo9 TREHALOSE
SYNTHASE/AMYLASE
TRES

(Mycolicibacterium
smegmatis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ASP A 154
ARG A 238
ARG A 164
 None
 0.96A 5eajB-3zo9A:
undetectable		 5eajB-3zo9A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag4 EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		3 ASP A 212
ARG A 128
ARG A 124
 None
 0.86A 5eajB-4ag4A:
undetectable		 5eajB-4ag4A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4am3 POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Caulobacter
vibrioides) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		3 ASP A 494
ARG A 327
ARG A 317
 None
 0.91A 5eajB-4am3A:
undetectable		 5eajB-4am3A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csw CUPIN 4 FAMILY
PROTEIN

(Rhodothermus
marinus) 		PF08007
(Cupin_4) 		3 ASP A 117
ARG A 169
ARG A  56
 None
 0.70A 5eajB-4cswA:
undetectable		 5eajB-4cswA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d65 PORIN 2

(Providencia
stuartii) 		PF00267
(Porin_1) 		3 ASP A 114
ARG A  38
ARG A  20
 None
 0.95A 5eajB-4d65A:
undetectable		 5eajB-4d65A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4c MULTIDRUG RESISTANCE
PROTEIN PGP-1

(Caenorhabditis
elegans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 ASP A  38
ARG A 867
ARG A 873
 None
 0.95A 5eajB-4f4cA:
undetectable		 5eajB-4f4cA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f7k LACCASE

(uncultured
bacterium) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ASP A 388
ARG A 364
ARG A 362
 None
 0.87A 5eajB-4f7kA:
undetectable		 5eajB-4f7kA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 ASP A 406
ARG A 935
ARG A 576
 None
 0.98A 5eajB-4fysA:
undetectable		 5eajB-4fysA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 ASP A 858
ARG A 204
ARG A 305
 None
None
SO4  A1014 (-3.0A)
 0.92A 5eajB-4fysA:
undetectable		 5eajB-4fysA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htp DNA LIGASE 4

(Homo sapiens) 		PF04675
(DNA_ligase_A_N) 		3 ASP A 210
ARG A  40
ARG A  47
 None
 0.88A 5eajB-4htpA:
undetectable		 5eajB-4htpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENC2

(Yersinia
entomophaga) 		no annotation 3 ASP B 114
ARG B 447
ARG B 444
 None
 0.91A 5eajB-4iglB:
undetectable		 5eajB-4iglB:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB
YENC2

(Yersinia
entomophaga;
Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN)
no annotation 		3 ASP B 257
ARG B 253
ARG A1342
 None
 0.92A 5eajB-4iglB:
undetectable		 5eajB-4iglB:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jzy CRYPTOCHROME-1

(Drosophila
melanogaster) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 ASP A 109
ARG A 278
ARG A  16
 None
 0.95A 5eajB-4jzyA:
undetectable		 5eajB-4jzyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6n AMINODEOXYCHORISMATE
LYASE

(Saccharomyces
cerevisiae) 		PF01063
(Aminotran_4) 		3 ASP A  99
ARG A 176
ARG A 118
 None
 0.96A 5eajB-4k6nA:
undetectable		 5eajB-4k6nA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxr PPE41
ESPG5

(Mycobacterium
tuberculosis;
Mycobacterium
tuberculosis) 		PF00823
(PPE)
PF14011
(ESX-1_EspG) 		3 ASP B 134
ARG C 109
ARG C 117
 None
 0.96A 5eajB-4kxrB:
undetectable		 5eajB-4kxrB:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfu EDS1
SENESCENCE-ASSOCIATE
D CARBOXYLESTERASE
101

(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		PF01764
(Lipase_3)
PF01764
(Lipase_3) 		3 ASP B 299
ARG A 425
ARG A 493
 None
 0.86A 5eajB-4nfuB:
undetectable		 5eajB-4nfuB:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Geobacter
sulfurreducens) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		3 ASP A 187
ARG A 404
ARG A 136
 None
 0.88A 5eajB-4nmeA:
undetectable		 5eajB-4nmeA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		3 ASP A 973
ARG A 165
ARG A1035
 None
 0.84A 5eajB-4o9xA:
undetectable		 5eajB-4o9xA:
5.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Ochrobactrum
anthropi) 		PF03480
(DctP) 		3 ASP A  76
ARG A 173
ARG A 152
 None
 0.97A 5eajB-4p47A:
undetectable		 5eajB-4p47A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmw DIS3-LIKE
EXONUCLEASE 2

(Mus musculus) 		PF00773
(RNB)
PF17216
(Rrp44_CSD1) 		3 ASP A 739
ARG A 272
ARG A  74
 None
None
U  C   7 ( 3.4A)
 0.83A 5eajB-4pmwA:
undetectable		 5eajB-4pmwA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qeo HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH4

(Arabidopsis
thaliana) 		PF00856
(SET)
PF02182
(SAD_SRA)
PF05033
(Pre-SET) 		3 ASP A 312
ARG A 350
ARG A 461
 None
 0.94A 5eajB-4qeoA:
undetectable		 5eajB-4qeoA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twe N-ACETYLATED-ALPHA-L
INKED ACIDIC
DIPEPTIDASE-LIKE
PROTEIN

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		3 ASP A 224
ARG A 168
ARG A 539
 None
 0.94A 5eajB-4tweA:
undetectable		 5eajB-4tweA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8h CRYPTOCHROME-2

(Mus musculus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 ASP A 119
ARG A 281
ARG A  32
 None
 0.97A 5eajB-4u8hA:
undetectable		 5eajB-4u8hA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbt PROBABLE
HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Sinorhizobium
meliloti) 		PF00155
(Aminotran_1_2) 		3 ASP A  95
ARG A  37
ARG A 335
 PLP  A 401 (-3.6A)
None
None
 0.98A 5eajB-4wbtA:
undetectable		 5eajB-4wbtA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzb NITROGENASE
MOLYBDENUM-IRON
PROTEIN ALPHA CHAIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		3 ASP A 234
ARG A 461
ARG A 439
 None
 0.92A 5eajB-4wzbA:
undetectable		 5eajB-4wzbA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yf1 LMO0812 PROTEIN

(Listeria
monocytogenes) 		PF13328
(HD_4) 		3 ASP A  57
ARG A 138
ARG A  91
 None
 0.99A 5eajB-4yf1A:
undetectable		 5eajB-4yf1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zsl MITOGEN-ACTIVATED
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		3 ASP A  53
ARG A 392
ARG A 122
 None
 0.78A 5eajB-4zslA:
undetectable		 5eajB-4zslA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aga DNA POLYMERASE THETA

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ASP A 216
ARG A 433
ARG A 480
 MG  A1895 (-3.2A)
None
None
 0.78A 5eajB-5agaA:
1.0		 5eajB-5agaA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME

(Homo sapiens) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 ASP A 573
ARG A 226
ARG A 585
 None
 0.95A 5eajB-5clwA:
undetectable		 5eajB-5clwA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN

(Measles
morbillivirus) 		PF00973
(Paramyxo_ncap)
PF13825
(Paramyxo_PNT) 		3 ASP A  77
ARG A 203
ARG A 211
 None
 0.99A 5eajB-5e4vA:
undetectable		 5eajB-5e4vA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 ASP A 564
ARG A 325
ARG A 526
 None
 0.75A 5eajB-5eawA:
undetectable		 5eajB-5eawA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5w GLYCINE--TRNA LIGASE
ALPHA SUBUNIT

(Aquifex
aeolicus) 		PF02091
(tRNA-synt_2e) 		3 ASP A 113
ARG A  70
ARG A 163
 None
None
G5A  A 300 (-4.0A)
 0.83A 5eajB-5f5wA:
undetectable		 5eajB-5f5wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcc HUTD

(Pseudomonas
fluorescens) 		PF05962
(HutD) 		3 ASP A  46
ARG A  61
ARG A  41
 None
CL  A 204 (-3.1A)
None
 0.94A 5eajB-5fccA:
undetectable		 5eajB-5fccA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvx TREHALOSE-PHOSPHATE
PHOSPHATASE

(Mycobacterium
tuberculosis) 		PF02358
(Trehalose_PPase) 		3 ASP A 330
ARG A  13
ARG A  63
 MG  A 401 ( 2.3A)
None
None
 0.94A 5eajB-5gvxA:
undetectable		 5eajB-5gvxA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjl TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE

(Streptococcus
porcinus) 		PF01791
(DeoC) 		3 ASP A 172
ARG A 277
ARG A  33
 None
SO4  A 401 (-3.6A)
SO4  A 403 (-2.5A)
 0.75A 5eajB-5hjlA:
undetectable		 5eajB-5hjlA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hqb ALPHA-GLUCOSIDASE

(Pseudoalteromonas
sp. K8) 		PF10566
(Glyco_hydro_97)
PF14508
(GH97_N)
PF14509
(GH97_C) 		3 ASP A 460
ARG A 591
ARG A  92
 None
 0.85A 5eajB-5hqbA:
undetectable		 5eajB-5hqbA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa) 		PF04453
(OstA_C) 		3 ASP A 214
ARG A 175
ARG A 207
 None
 0.99A 5eajB-5ivaA:
undetectable		 5eajB-5ivaA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jou ALPHA-XYLOSIDASE
BOGH31A

(Bacteroides
ovatus) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF17137
(DUF5110) 		3 ASP A 167
ARG A 823
ARG A 799
 None
 0.97A 5eajB-5jouA:
undetectable		 5eajB-5jouA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT
ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum;
Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B)
PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		3 ASP B 334
ARG A 445
ARG B 121
 None
 0.93A 5eajB-5l9wB:
undetectable		 5eajB-5l9wB:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL

(Photorhabdus
asymbiotica) 		PF03984
(DUF346) 		3 ASP A 364
ARG A 144
ARG A  97
 None
 0.96A 5eajB-5mxfA:
undetectable		 5eajB-5mxfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubm COMPLEMENT C1S
SUBCOMPONENT
GIGASTASIN

(Homo sapiens;
Haementeria
ghilianii) 		no annotation
no annotation 		3 ASP I  60
ARG A 572
ARG I  65
 None
 0.97A 5eajB-5ubmI:
undetectable		 5eajB-5ubmI:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Acinetobacter
baumannii) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 ASP A 369
ARG A 265
ARG A 202
 None
EDO  A 604 ( 2.8A)
EDO  A 604 ( 4.8A)
 0.92A 5eajB-5vpuA:
1.7		 5eajB-5vpuA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 3 ASP A 107
ARG A  95
ARG A 161
 None
 0.90A 5eajB-5wlhA:
undetectable		 5eajB-5wlhA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbi PROBABLE
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		no annotation 3 ASP A 165
ARG A 123
ARG A 252
 None
 0.93A 5eajB-5xbiA:
undetectable		 5eajB-5xbiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbt PROBABLE
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		no annotation 3 ASP A 165
ARG A 123
ARG A 252
 None
 0.72A 5eajB-5xbtA:
undetectable		 5eajB-5xbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2v RUBISCO OPERON
TRANSCRIPTIONAL
REGULATOR

(Synechocystis
sp. PCC 6803) 		no annotation 3 ASP A  72
ARG A  96
ARG A 136
 None
 0.89A 5eajB-5y2vA:
undetectable		 5eajB-5y2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydj ACETYLCHOLINESTERASE

(Anopheles
gambiae) 		no annotation 3 ASP A 456
ARG A 210
ARG A 310
 None
 0.98A 5eajB-5ydjA:
undetectable		 5eajB-5ydjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yv5 ATPASE RIL

(Pyrococcus
furiosus) 		no annotation 3 ASP A 513
ARG A 331
ARG A 560
 None
 0.98A 5eajB-5yv5A:
undetectable		 5eajB-5yv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 3 ASP A1875
ARG A1906
ARG A1907
 None
 0.84A 5eajB-5zalA:
undetectable		 5eajB-5zalA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zc2 -

(-) 		no annotation 3 ASP B 138
ARG B  99
ARG B 247
 None
FMN  B 401 (-4.1A)
None
 0.90A 5eajB-5zc2B:
undetectable		 5eajB-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6arx ACETYLCHOLINESTERASE

(Anopheles
gambiae) 		no annotation 3 ASP A 456
ARG A 210
ARG A 310
 None
 0.96A 5eajB-6arxA:
undetectable		 5eajB-6arxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dip NOCTURNIN

(Homo sapiens) 		no annotation 3 ASP A 234
ARG A 367
ARG A 290
 None
 0.75A 5eajB-6dipA:
undetectable		 5eajB-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6esl BACTERIAL LEUCYL
AMINOPEPTIDASE

(Legionella
pneumophila) 		no annotation 3 ASP A 354
ARG A 131
ARG A 201
 None
 0.98A 5eajB-6eslA:
undetectable		 5eajB-6eslA:
undetectable