SIMILAR PATTERNS OF AMINO ACIDS FOR 5DZK_4_BEZ4801_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a8s CHLOROPEROXIDASE F

(Pseudomonas
fluorescens) 		PF00561
(Abhydrolase_1) 		4 PHE A 200
ARG A 144
ILE A 143
ILE A 197
 PPI  A 278 (-3.6A)
None
None
None
 1.01A 5dzk4-1a8sA:
undetectable
5dzkg-1a8sA:
1.0
5dzkm-1a8sA:
0.2
5dzkn-1a8sA:
0.5		 5dzk4-1a8sA:
0.75
5dzkg-1a8sA:
24.57
5dzkm-1a8sA:
22.89
5dzkn-1a8sA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bp1 BACTERICIDAL/PERMEAB
ILITY-INCREASING
PROTEIN

(Homo sapiens) 		PF01273
(LBP_BPI_CETP)
PF02886
(LBP_BPI_CETP_C) 		4 LEU A 157
PHE A  53
ILE A 155
ILE A 146
 None
 1.06A 5dzk4-1bp1A:
undetectable
5dzkg-1bp1A:
undetectable
5dzkm-1bp1A:
undetectable
5dzkn-1bp1A:
undetectable		 5dzk4-1bp1A:
0.52
5dzkg-1bp1A:
19.73
5dzkm-1bp1A:
18.96
5dzkn-1bp1A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d0n HORSE PLASMA
GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		4 LEU A 191
ARG A 225
ILE A 197
ILE A 220
 None
 0.79A 5dzk4-1d0nA:
undetectable
5dzkg-1d0nA:
0.0
5dzkm-1d0nA:
0.0
5dzkn-1d0nA:
0.0		 5dzk4-1d0nA:
1.46
5dzkg-1d0nA:
15.07
5dzkm-1d0nA:
14.50
5dzkn-1d0nA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eke RIBONUCLEASE HII

(Methanocaldococcus
jannaschii) 		PF01351
(RNase_HII) 		4 LEU A  36
PHE A  23
ARG A  29
ILE A  25
 None
 0.92A 5dzk4-1ekeA:
undetectable
5dzkg-1ekeA:
undetectable
5dzkm-1ekeA:
undetectable
5dzkn-1ekeA:
0.0		 5dzk4-1ekeA:
3.57
5dzkg-1ekeA:
22.13
5dzkm-1ekeA:
21.52
5dzkn-1ekeA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE

(Neisseria
meningitidis) 		PF02348
(CTP_transf_3) 		4 LEU A 102
PHE A  45
ILE A 178
ILE A 115
 None
 0.96A 5dzk4-1eziA:
undetectable
5dzkg-1eziA:
undetectable
5dzkm-1eziA:
0.0
5dzkn-1eziA:
undetectable		 5dzk4-1eziA:
1.94
5dzkg-1eziA:
22.27
5dzkm-1eziA:
24.15
5dzkn-1eziA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0v PROTEINASE A

(Saccharomyces
cerevisiae) 		PF00026
(Asp) 		4 PHE A 175
ARG A 150
ILE A 312
ILE A 170
 None
 1.03A 5dzk4-1g0vA:
undetectable
5dzkg-1g0vA:
undetectable
5dzkm-1g0vA:
undetectable
5dzkn-1g0vA:
undetectable		 5dzk4-1g0vA:
1.36
5dzkg-1g0vA:
21.36
5dzkm-1g0vA:
19.29
5dzkn-1g0vA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i4w MITOCHONDRIAL
REPLICATION PROTEIN
MTF1

(Saccharomyces
cerevisiae) 		PF00398
(RrnaAD) 		4 LEU A 244
PHE A 229
ILE A 242
ILE A 234
 None
 0.99A 5dzk4-1i4wA:
undetectable
5dzkg-1i4wA:
0.0
5dzkm-1i4wA:
0.0
5dzkn-1i4wA:
0.0		 5dzk4-1i4wA:
2.27
5dzkg-1i4wA:
20.85
5dzkm-1i4wA:
19.67
5dzkn-1i4wA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 LEU S 760
PHE S 776
ILE S 757
ILE S 774
 None
 1.04A 5dzk4-1i84S:
undetectable
5dzkg-1i84S:
undetectable
5dzkm-1i84S:
0.0
5dzkn-1i84S:
0.0		 5dzk4-1i84S:
0.89
5dzkg-1i84S:
11.39
5dzkm-1i84S:
11.06
5dzkn-1i84S:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3j BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00303
(Thymidylat_synt) 		4 LEU C 560
PHE C 312
ILE C 557
ILE C 307
 None
 0.85A 5dzk4-1j3jC:
undetectable
5dzkg-1j3jC:
0.0
5dzkm-1j3jC:
0.0
5dzkn-1j3jC:
0.0		 5dzk4-1j3jC:
2.25
5dzkg-1j3jC:
21.10
5dzkm-1j3jC:
19.94
5dzkn-1j3jC:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl0 S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROENZYME

(Homo sapiens) 		PF01536
(SAM_decarbox) 		4 PHE A 325
ARG A 269
ILE A 268
ILE A 302
 None
 1.08A 5dzk4-1jl0A:
undetectable
5dzkg-1jl0A:
undetectable
5dzkm-1jl0A:
undetectable
5dzkn-1jl0A:
undetectable		 5dzk4-1jl0A:
14.29
5dzkg-1jl0A:
18.73
5dzkm-1jl0A:
21.83
5dzkn-1jl0A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k0f PERIPLASMIC
ZINC-BINDING PROTEIN
TROA

(Treponema
pallidum) 		PF01297
(ZnuA) 		4 LEU A 216
ARG A 260
ILE A 245
ILE A 272
 None
 1.05A 5dzk4-1k0fA:
undetectable
5dzkg-1k0fA:
undetectable
5dzkm-1k0fA:
undetectable
5dzkn-1k0fA:
undetectable		 5dzk4-1k0fA:
1.60
5dzkg-1k0fA:
21.30
5dzkm-1k0fA:
20.85
5dzkn-1k0fA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldk CULLIN HOMOLOG

(Homo sapiens) 		PF00888
(Cullin) 		4 LEU A 200
ARG A 274
ILE A 201
ILE A 187
 None
 0.98A 5dzk4-1ldkA:
undetectable
5dzkg-1ldkA:
undetectable
5dzkm-1ldkA:
undetectable
5dzkn-1ldkA:
undetectable		 5dzk4-1ldkA:
2.22
5dzkg-1ldkA:
19.40
5dzkm-1ldkA:
19.24
5dzkn-1ldkA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pg5 ASPARTATE
CARBAMOYLTRANSFERASE

(Sulfolobus
acidocaldarius) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 PHE A 110
ARG A  89
ILE A  88
ILE A 114
 None
 1.08A 5dzk4-1pg5A:
undetectable
5dzkg-1pg5A:
undetectable
5dzkm-1pg5A:
undetectable
5dzkn-1pg5A:
undetectable		 5dzk4-1pg5A:
1.07
5dzkg-1pg5A:
22.11
5dzkm-1pg5A:
22.92
5dzkn-1pg5A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
IRON-SULFUR PROTEIN

(Wolinella
succinogenes) 		PF13085
(Fer2_3)
PF13183
(Fer4_8) 		4 LEU B  80
PHE B  84
ILE B  36
ILE B  69
 None
 0.95A 5dzk4-1qlbB:
undetectable
5dzkg-1qlbB:
undetectable
5dzkm-1qlbB:
undetectable
5dzkn-1qlbB:
undetectable		 5dzk4-1qlbB:
2.17
5dzkg-1qlbB:
24.16
5dzkm-1qlbB:
18.25
5dzkn-1qlbB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rgi GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		4 LEU G 191
ARG G 225
ILE G 197
ILE G 220
 None
 0.77A 5dzk4-1rgiG:
undetectable
5dzkg-1rgiG:
undetectable
5dzkm-1rgiG:
undetectable
5dzkn-1rgiG:
undetectable		 5dzk4-1rgiG:
1.45
5dzkg-1rgiG:
21.77
5dzkm-1rgiG:
19.43
5dzkn-1rgiG:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s04 HYPOTHETICAL PROTEIN
PF0455

(Pyrococcus
furiosus) 		PF04266
(ASCH) 		4 PHE A  42
ARG A  18
ILE A 105
ILE A  15
 None
 0.83A 5dzk4-1s04A:
undetectable
5dzkg-1s04A:
undetectable
5dzkm-1s04A:
undetectable
5dzkn-1s04A:
undetectable		 5dzk4-1s04A:
16.67
5dzkg-1s04A:
20.95
5dzkm-1s04A:
19.67
5dzkn-1s04A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sqi 4-HYDROXYPHENYLPYRUV
IC ACID DIOXYGENASE

(Rattus
norvegicus) 		PF00903
(Glyoxalase) 		4 LEU A 323
ARG A 282
ILE A 322
ILE A 278
 None
 1.07A 5dzk4-1sqiA:
undetectable
5dzkg-1sqiA:
undetectable
5dzkm-1sqiA:
undetectable
5dzkn-1sqiA:
undetectable		 5dzk4-1sqiA:
0.67
5dzkg-1sqiA:
19.46
5dzkm-1sqiA:
18.18
5dzkn-1sqiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txd RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 12

(Homo sapiens) 		PF00621
(RhoGEF) 		4 PHE A 796
ARG A 788
ILE A 947
ILE A 792
 None
 1.02A 5dzk4-1txdA:
undetectable
5dzkg-1txdA:
undetectable
5dzkm-1txdA:
undetectable
5dzkn-1txdA:
undetectable		 5dzk4-1txdA:
12.50
5dzkg-1txdA:
20.00
5dzkm-1txdA:
17.88
5dzkn-1txdA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u9z RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE

(Methanocaldococcus
jannaschii) 		PF00156
(Pribosyltran)
PF13793
(Pribosyltran_N) 		4 LEU A 108
PHE A 133
ILE A 105
ILE A 129
 None
 1.05A 5dzk4-1u9zA:
undetectable
5dzkg-1u9zA:
2.0
5dzkm-1u9zA:
1.4
5dzkn-1u9zA:
1.4		 5dzk4-1u9zA:
0.70
5dzkg-1u9zA:
22.44
5dzkm-1u9zA:
24.83
5dzkn-1u9zA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ys4 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 PHE A 274
ARG A 336
ILE A 127
ILE A 164
 None
 1.05A 5dzk4-1ys4A:
undetectable
5dzkg-1ys4A:
undetectable
5dzkm-1ys4A:
undetectable
5dzkn-1ys4A:
undetectable		 5dzk4-1ys4A:
7.14
5dzkg-1ys4A:
20.83
5dzkm-1ys4A:
22.69
5dzkn-1ys4A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a4v PEROXIREDOXIN DOT5

(Saccharomyces
cerevisiae) 		PF00578
(AhpC-TSA) 		4 LEU A  74
PHE A  96
ILE A  82
ILE A  87
 None
 1.02A 5dzk4-2a4vA:
undetectable
5dzkg-2a4vA:
undetectable
5dzkm-2a4vA:
undetectable
5dzkn-2a4vA:
undetectable		 5dzk4-2a4vA:
2.08
5dzkg-2a4vA:
19.46
5dzkm-2a4vA:
19.60
5dzkn-2a4vA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi3 PHOSPHOSERINE
AMINOTRANSFERASE

(Bacillus
alcalophilus) 		PF00266
(Aminotran_5) 		4 LEU A  70
ARG A  58
ILE A  69
ILE A  63
 None
 0.96A 5dzk4-2bi3A:
undetectable
5dzkg-2bi3A:
undetectable
5dzkm-2bi3A:
undetectable
5dzkn-2bi3A:
undetectable		 5dzk4-2bi3A:
7.41
5dzkg-2bi3A:
21.43
5dzkm-2bi3A:
20.27
5dzkn-2bi3A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c5q RRAA-LIKE PROTEIN
YER010C

(Saccharomyces
cerevisiae) 		PF03737
(RraA-like) 		4 PHE A 118
ARG A 184
ILE A 175
ILE A 169
 None
EDO  A1234 (-2.7A)
None
CME  A 170 ( 3.9A)
 0.90A 5dzk4-2c5qA:
undetectable
5dzkg-2c5qA:
undetectable
5dzkm-2c5qA:
undetectable
5dzkn-2c5qA:
undetectable		 5dzk4-2c5qA:
10.00
5dzkg-2c5qA:
22.69
5dzkm-2c5qA:
24.15
5dzkn-2c5qA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2chr CHLOROMUCONATE
CYCLOISOMERASE

(Cupriavidus
necator) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 324
PHE A 328
ILE A 134
ILE A 341
 None
 0.98A 5dzk4-2chrA:
undetectable
5dzkg-2chrA:
1.7
5dzkm-2chrA:
2.0
5dzkn-2chrA:
undetectable		 5dzk4-2chrA:
2.63
5dzkg-2chrA:
21.66
5dzkm-2chrA:
21.20
5dzkn-2chrA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cnd NADH-DEPENDENT
NITRATE REDUCTASE

(Zea mays) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 LEU A 240
PHE A 267
ILE A 142
ILE A 252
 None
 0.94A 5dzk4-2cndA:
undetectable
5dzkg-2cndA:
undetectable
5dzkm-2cndA:
undetectable
5dzkn-2cndA:
undetectable		 5dzk4-2cndA:
1.09
5dzkg-2cndA:
20.00
5dzkm-2cndA:
22.34
5dzkn-2cndA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e8g HYPOTHETICAL PROTEIN
PH0536

(Pyrococcus
horikoshii) 		PF01588
(tRNA_bind) 		4 LEU A  41
PHE A  20
ILE A  39
ILE A  24
 None
 0.98A 5dzk4-2e8gA:
undetectable
5dzkg-2e8gA:
undetectable
5dzkm-2e8gA:
undetectable
5dzkn-2e8gA:
undetectable		 5dzk4-2e8gA:
1.28
5dzkg-2e8gA:
20.73
5dzkm-2e8gA:
22.57
5dzkn-2e8gA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4o PEPTIDE N-GLYCANASE

(Mus musculus) 		PF01841
(Transglut_core) 		4 LEU A 414
PHE A 376
ILE A 411
ILE A 374
 None
 1.04A 5dzk4-2f4oA:
undetectable
5dzkg-2f4oA:
2.1
5dzkm-2f4oA:
undetectable
5dzkn-2f4oA:
undetectable		 5dzk4-2f4oA:
1.01
5dzkg-2f4oA:
21.05
5dzkm-2f4oA:
21.26
5dzkn-2f4oA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fq4 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Bacillus cereus) 		PF00440
(TetR_N)
PF16859
(TetR_C_11) 		4 LEU A 157
PHE A 186
ILE A 158
ILE A  84
 None
 0.99A 5dzk4-2fq4A:
undetectable
5dzkg-2fq4A:
undetectable
5dzkm-2fq4A:
undetectable
5dzkn-2fq4A:
undetectable		 5dzk4-2fq4A:
8.00
5dzkg-2fq4A:
25.82
5dzkm-2fq4A:
25.56
5dzkn-2fq4A:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4o 3-ISOPROPYLMALATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00180
(Iso_dh) 		4 LEU A 240
PHE A 117
ILE A 237
ILE A 227
 None
 1.07A 5dzk4-2g4oA:
undetectable
5dzkg-2g4oA:
undetectable
5dzkm-2g4oA:
undetectable
5dzkn-2g4oA:
undetectable		 5dzk4-2g4oA:
0.59
5dzkg-2g4oA:
19.47
5dzkm-2g4oA:
21.47
5dzkn-2g4oA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inv INSULIN
FRUCTOTRANSFERASE

(Bacillus sp.
snu-7) 		no annotation 4 LEU A 109
PHE A 183
ILE A  78
ILE A 122
 None
 1.01A 5dzk4-2invA:
undetectable
5dzkg-2invA:
2.2
5dzkm-2invA:
undetectable
5dzkn-2invA:
undetectable		 5dzk4-2invA:
0.85
5dzkg-2invA:
21.98
5dzkm-2invA:
19.26
5dzkn-2invA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2op6 HEAT SHOCK 70 KDA
PROTEIN D

(Caenorhabditis
elegans) 		PF00012
(HSP70) 		4 LEU A 526
PHE A 503
ILE A 465
ILE A 428
 None
 0.89A 5dzk4-2op6A:
undetectable
5dzkg-2op6A:
undetectable
5dzkm-2op6A:
undetectable
5dzkn-2op6A:
undetectable		 5dzk4-2op6A:
0.66
5dzkg-2op6A:
20.81
5dzkm-2op6A:
20.73
5dzkn-2op6A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6u KINESIN-LIKE PROTEIN
KIF3B

(Homo sapiens) 		PF00225
(Kinesin) 		4 LEU A 139
PHE A 127
ILE A 223
ILE A 126
 None
 1.06A 5dzk4-3b6uA:
undetectable
5dzkg-3b6uA:
undetectable
5dzkm-3b6uA:
undetectable
5dzkn-3b6uA:
undetectable		 5dzk4-3b6uA:
1.18
5dzkg-3b6uA:
20.53
5dzkm-3b6uA:
19.10
5dzkn-3b6uA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dak SERINE/THREONINE-PRO
TEIN KINASE OSR1

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 220
PHE A 264
ILE A 218
ILE A 268
 None
 1.06A 5dzk4-3dakA:
undetectable
5dzkg-3dakA:
undetectable
5dzkm-3dakA:
undetectable
5dzkn-3dakA:
undetectable		 5dzk4-3dakA:
3.57
5dzkg-3dakA:
21.43
5dzkm-3dakA:
20.20
5dzkn-3dakA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dl1 PUTATIVE
METAL-DEPENDENT
HYDROLASE

(Klebsiella
pneumoniae) 		PF06167
(Peptidase_M90) 		4 LEU A 146
PHE A  73
ILE A 135
ILE A  69
 None
 1.02A 5dzk4-3dl1A:
undetectable
5dzkg-3dl1A:
undetectable
5dzkm-3dl1A:
undetectable
5dzkn-3dl1A:
undetectable		 5dzk4-3dl1A:
1.36
5dzkg-3dl1A:
22.26
5dzkm-3dl1A:
24.03
5dzkn-3dl1A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec7 PUTATIVE
DEHYDROGENASE

(Salmonella
enterica) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 LEU A 306
PHE A 125
ILE A 178
ILE A 175
 None
 1.06A 5dzk4-3ec7A:
undetectable
5dzkg-3ec7A:
undetectable
5dzkm-3ec7A:
undetectable
5dzkn-3ec7A:
1.5		 5dzk4-3ec7A:
0.97
5dzkg-3ec7A:
21.30
5dzkm-3ec7A:
20.55
5dzkn-3ec7A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fju CARBOXYPEPTIDASE A1

(Homo sapiens) 		PF00246
(Peptidase_M14) 		4 LEU A 103
PHE A  96
ILE A 105
ILE A  86
 None
 1.07A 5dzk4-3fjuA:
undetectable
5dzkg-3fjuA:
undetectable
5dzkm-3fjuA:
undetectable
5dzkn-3fjuA:
undetectable		 5dzk4-3fjuA:
8.33
5dzkg-3fjuA:
20.55
5dzkm-3fjuA:
22.56
5dzkn-3fjuA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fz5 POSSIBLE
2-HYDROXYCHROMENE-2-
CARBOXYLATE
ISOMERASE

(Rhodobacter
sphaeroides) 		PF01323
(DSBA) 		4 LEU A 175
ARG A  31
ILE A   4
ILE A 194
 None
 1.02A 5dzk4-3fz5A:
undetectable
5dzkg-3fz5A:
undetectable
5dzkm-3fz5A:
undetectable
5dzkn-3fz5A:
undetectable		 5dzk4-3fz5A:
1.36
5dzkg-3fz5A:
23.63
5dzkm-3fz5A:
22.02
5dzkn-3fz5A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2z MANNITOL-1-PHOSPHATE
5-DEHYDROGENASE

(Shigella
flexneri) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		4 LEU A 138
PHE A 152
ILE A  99
ILE A 117
 None
 1.06A 5dzk4-3h2zA:
undetectable
5dzkg-3h2zA:
undetectable
5dzkm-3h2zA:
undetectable
5dzkn-3h2zA:
undetectable		 5dzk4-3h2zA:
10.00
5dzkg-3h2zA:
21.00
5dzkm-3h2zA:
20.41
5dzkn-3h2zA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hlz UNCHARACTERIZED
PROTEIN BT_1490

(Bacteroides
thetaiotaomicron) 		PF12712
(DUF3805)
PF12713
(DUF3806) 		4 LEU A 142
ARG A 146
ILE A 143
ILE A   7
 None
 1.00A 5dzk4-3hlzA:
undetectable
5dzkg-3hlzA:
undetectable
5dzkm-3hlzA:
undetectable
5dzkn-3hlzA:
undetectable		 5dzk4-3hlzA:
1.35
5dzkg-3hlzA:
23.51
5dzkm-3hlzA:
22.47
5dzkn-3hlzA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ics COENZYME A-DISULFIDE
REDUCTASE

(Bacillus
anthracis) 		PF00581
(Rhodanese)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 110
ARG A   3
ILE A   5
ILE A 316
 None
 1.09A 5dzk4-3icsA:
undetectable
5dzkg-3icsA:
undetectable
5dzkm-3icsA:
undetectable
5dzkn-3icsA:
undetectable		 5dzk4-3icsA:
2.11
5dzkg-3icsA:
18.49
5dzkm-3icsA:
18.96
5dzkn-3icsA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihk THIAMIN
PYROPHOSPHOKINASE

(Streptococcus
mutans) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 LEU A 132
PHE A  98
ILE A 204
ILE A 109
 None
 1.06A 5dzk4-3ihkA:
undetectable
5dzkg-3ihkA:
undetectable
5dzkm-3ihkA:
undetectable
5dzkn-3ihkA:
undetectable		 5dzk4-3ihkA:
6.06
5dzkg-3ihkA:
20.00
5dzkm-3ihkA:
23.04
5dzkn-3ihkA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3keh GLUCOCEREBROSIDASE

(Homo sapiens) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		4 LEU A 160
PHE A 109
ILE A 161
ILE A 119
 None
 1.08A 5dzk4-3kehA:
undetectable
5dzkg-3kehA:
undetectable
5dzkm-3kehA:
undetectable
5dzkn-3kehA:
undetectable		 5dzk4-3kehA:
3.03
5dzkg-3kehA:
18.43
5dzkm-3kehA:
17.23
5dzkn-3kehA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT

(Acetoanaerobium
sticklandii) 		PF02310
(B12-binding)
PF09043
(Lys-AminoMut_A)
PF16554
(OAM_dimer) 		4 LEU A 665
ARG A 693
ILE A 664
ILE A 696
 B12  A1801 ( 3.8A)
None
None
None
 1.03A 5dzk4-3koyA:
undetectable
5dzkg-3koyA:
2.5
5dzkm-3koyA:
undetectable
5dzkn-3koyA:
undetectable		 5dzk4-3koyA:
0.63
5dzkg-3koyA:
14.80
5dzkm-3koyA:
14.08
5dzkn-3koyA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kw0 CYSTEINE PEPTIDASE

(Bacillus cereus) 		PF05708
(Peptidase_C92) 		4 LEU A 141
PHE A 176
ILE A 139
ILE A 153
 None
 0.94A 5dzk4-3kw0A:
undetectable
5dzkg-3kw0A:
undetectable
5dzkm-3kw0A:
undetectable
5dzkn-3kw0A:
undetectable		 5dzk4-3kw0A:
1.65
5dzkg-3kw0A:
20.97
5dzkm-3kw0A:
22.36
5dzkn-3kw0A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Mycobacterium
tuberculosis) 		PF13561
(adh_short_C2) 		4 LEU A 292
PHE A 233
ILE A 343
ILE A 428
 None
 0.96A 5dzk4-3m1lA:
undetectable
5dzkg-3m1lA:
2.2
5dzkm-3m1lA:
undetectable
5dzkn-3m1lA:
undetectable		 5dzk4-3m1lA:
6.06
5dzkg-3m1lA:
19.34
5dzkm-3m1lA:
19.63
5dzkn-3m1lA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3onq REGULATOR OF
POLYKETIDE SYNTHASE
EXPRESSION

(Bifidobacterium
adolescentis) 		PF13556
(HTH_30) 		4 LEU A  93
PHE A 115
ILE A  85
ILE A  71
 None
 1.04A 5dzk4-3onqA:
undetectable
5dzkg-3onqA:
undetectable
5dzkm-3onqA:
undetectable
5dzkn-3onqA:
undetectable		 5dzk4-3onqA:
1.20
5dzkg-3onqA:
23.28
5dzkm-3onqA:
22.94
5dzkn-3onqA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pb0 DIHYDRODIPICOLINATE
SYNTHASE

(Thermotoga
maritima) 		PF00701
(DHDPS) 		4 LEU A  38
PHE A   2
ILE A  39
ILE A 206
 None
 1.04A 5dzk4-3pb0A:
undetectable
5dzkg-3pb0A:
3.4
5dzkm-3pb0A:
2.6
5dzkn-3pb0A:
1.5		 5dzk4-3pb0A:
0.67
5dzkg-3pb0A:
22.95
5dzkm-3pb0A:
22.60
5dzkn-3pb0A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppl ASPARTATE
AMINOTRANSFERASE

(Corynebacterium
glutamicum) 		PF12897
(Aminotran_MocR) 		4 LEU A  89
PHE A 269
ILE A  85
ILE A  82
 None
 1.00A 5dzk4-3pplA:
undetectable
5dzkg-3pplA:
undetectable
5dzkm-3pplA:
undetectable
5dzkn-3pplA:
undetectable		 5dzk4-3pplA:
3.64
5dzkg-3pplA:
19.91
5dzkm-3pplA:
19.58
5dzkn-3pplA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rru TOM1L1 PROTEIN

(Homo sapiens) 		PF00790
(VHS) 		4 LEU A  75
PHE A  87
ILE A  76
ILE A  91
 None
 1.08A 5dzk4-3rruA:
undetectable
5dzkg-3rruA:
undetectable
5dzkm-3rruA:
undetectable
5dzkn-3rruA:
undetectable		 5dzk4-3rruA:
1.87
5dzkg-3rruA:
20.81
5dzkm-3rruA:
21.15
5dzkn-3rruA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s48 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H

(Staphylococcus
aureus) 		PF05031
(NEAT) 		4 LEU A 217
PHE A 159
ILE A 131
ILE A 150
 None
 0.98A 5dzk4-3s48A:
undetectable
5dzkg-3s48A:
undetectable
5dzkm-3s48A:
undetectable
5dzkn-3s48A:
undetectable		 5dzk4-3s48A:
3.85
5dzkg-3s48A:
20.81
5dzkm-3s48A:
20.10
5dzkn-3s48A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3saj GLUTAMATE RECEPTOR 1

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 LEU A 212
PHE A 235
ILE A 211
ILE A 118
 None
 1.09A 5dzk4-3sajA:
undetectable
5dzkg-3sajA:
undetectable
5dzkm-3sajA:
undetectable
5dzkn-3sajA:
undetectable		 5dzk4-3sajA:
4.76
5dzkg-3sajA:
20.58
5dzkm-3sajA:
19.49
5dzkn-3sajA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txm 26S PROTEASOME
REGULATORY COMPLEX
SUBUNIT P42B

(Drosophila
melanogaster) 		PF01399
(PCI) 		4 LEU A 256
PHE A 232
ILE A 318
ILE A 216
 None
 0.96A 5dzk4-3txmA:
undetectable
5dzkg-3txmA:
undetectable
5dzkm-3txmA:
undetectable
5dzkn-3txmA:
undetectable		 5dzk4-3txmA:
1.59
5dzkg-3txmA:
20.25
5dzkm-3txmA:
19.18
5dzkn-3txmA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0b OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN

(Mycolicibacterium
smegmatis) 		PF13561
(adh_short_C2) 		4 LEU A 288
PHE A 229
ILE A 339
ILE A 424
 None
 0.84A 5dzk4-3u0bA:
undetectable
5dzkg-3u0bA:
undetectable
5dzkm-3u0bA:
undetectable
5dzkn-3u0bA:
undetectable		 5dzk4-3u0bA:
4.08
5dzkg-3u0bA:
20.84
5dzkm-3u0bA:
18.72
5dzkn-3u0bA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um6 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		4 LEU A 560
PHE A 312
ILE A 557
ILE A 307
 None
 0.90A 5dzk4-3um6A:
undetectable
5dzkg-3um6A:
undetectable
5dzkm-3um6A:
undetectable
5dzkn-3um6A:
undetectable		 5dzk4-3um6A:
1.31
5dzkg-3um6A:
13.32
5dzkm-3um6A:
14.89
5dzkn-3um6A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs7 PYRIDOXAL KINASE

(Trypanosoma
brucei) 		PF08543
(Phos_pyr_kin) 		4 LEU A  81
PHE A 114
ILE A   9
ILE A  94
 None
 0.81A 5dzk4-3zs7A:
undetectable
5dzkg-3zs7A:
undetectable
5dzkm-3zs7A:
undetectable
5dzkn-3zs7A:
undetectable		 5dzk4-3zs7A:
0.85
5dzkg-3zs7A:
22.62
5dzkm-3zs7A:
23.15
5dzkn-3zs7A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cxh ELONGATION FACTOR 1A

(Oryctolagus
cuniculus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 LEU A 113
PHE A 189
ILE A 147
ILE A 187
 None
 1.06A 5dzk4-4cxhA:
undetectable
5dzkg-4cxhA:
2.0
5dzkm-4cxhA:
2.1
5dzkn-4cxhA:
2.3		 5dzk4-4cxhA:
7.41
5dzkg-4cxhA:
18.12
5dzkm-4cxhA:
17.31
5dzkn-4cxhA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dq6 PUTATIVE PYRIDOXAL
PHOSPHATE-DEPENDENT
TRANSFERASE

(Clostridioides
difficile) 		PF00155
(Aminotran_1_2) 		4 LEU A 167
PHE A 124
ILE A 198
ILE A 100
 None
 0.89A 5dzk4-4dq6A:
undetectable
5dzkg-4dq6A:
undetectable
5dzkm-4dq6A:
undetectable
5dzkn-4dq6A:
undetectable		 5dzk4-4dq6A:
5.71
5dzkg-4dq6A:
19.49
5dzkm-4dq6A:
18.95
5dzkn-4dq6A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dz4 AGMATINASE

(Burkholderia
thailandensis) 		PF00491
(Arginase) 		4 LEU A 225
PHE A 158
ILE A 228
ILE A 156
 None
 1.09A 5dzk4-4dz4A:
undetectable
5dzkg-4dz4A:
1.5
5dzkm-4dz4A:
1.0
5dzkn-4dz4A:
undetectable		 5dzk4-4dz4A:
1.37
5dzkg-4dz4A:
21.26
5dzkm-4dz4A:
22.53
5dzkn-4dz4A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efc ADENYLOSUCCINATE
LYASE

(Trypanosoma
brucei) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		4 LEU A 157
PHE A  41
ILE A 154
ILE A 150
 None
 1.07A 5dzk4-4efcA:
undetectable
5dzkg-4efcA:
undetectable
5dzkm-4efcA:
undetectable
5dzkn-4efcA:
undetectable		 5dzk4-4efcA:
0.59
5dzkg-4efcA:
19.79
5dzkm-4efcA:
18.11
5dzkn-4efcA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egu HISTIDINE TRIAD
(HIT) PROTEIN

(Clostridioides
difficile) 		PF01230
(HIT) 		4 LEU A 106
PHE A  79
ILE A  41
ILE A  73
 None
 1.01A 5dzk4-4eguA:
undetectable
5dzkg-4eguA:
undetectable
5dzkm-4eguA:
undetectable
5dzkn-4eguA:
undetectable		 5dzk4-4eguA:
6.06
5dzkg-4eguA:
19.25
5dzkm-4eguA:
18.81
5dzkn-4eguA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fhn NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 LEU B 466
PHE B 427
ILE B 436
ILE B 426
 None
 1.08A 5dzk4-4fhnB:
undetectable
5dzkg-4fhnB:
undetectable
5dzkm-4fhnB:
undetectable
5dzkn-4fhnB:
undetectable		 5dzk4-4fhnB:
0.18
5dzkg-4fhnB:
11.01
5dzkm-4fhnB:
10.65
5dzkn-4fhnB:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gis ENOLASE

(Vibrio harveyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 203
PHE A 189
ILE A 230
ILE A 222
 None
 1.00A 5dzk4-4gisA:
undetectable
5dzkg-4gisA:
2.1
5dzkm-4gisA:
undetectable
5dzkn-4gisA:
undetectable		 5dzk4-4gisA:
2.44
5dzkg-4gisA:
20.47
5dzkm-4gisA:
18.27
5dzkn-4gisA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl0 LMO0810 PROTEIN

(Listeria
monocytogenes) 		PF13416
(SBP_bac_8) 		4 LEU A  50
PHE A 281
ILE A  51
ILE A  39
 None
None
PG4  A 502 ( 4.3A)
None
 1.00A 5dzk4-4gl0A:
undetectable
5dzkg-4gl0A:
undetectable
5dzkm-4gl0A:
undetectable
5dzkn-4gl0A:
undetectable		 5dzk4-4gl0A:
2.53
5dzkg-4gl0A:
22.52
5dzkm-4gl0A:
22.12
5dzkn-4gl0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hkm ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Xanthomonas
campestris) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 LEU A 291
PHE A  93
ILE A 293
ILE A  95
 None
 1.09A 5dzk4-4hkmA:
undetectable
5dzkg-4hkmA:
undetectable
5dzkm-4hkmA:
undetectable
5dzkn-4hkmA:
undetectable		 5dzk4-4hkmA:
0.71
5dzkg-4hkmA:
20.67
5dzkm-4hkmA:
19.55
5dzkn-4hkmA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw9 MECHANOSENSITIVE
CHANNEL MSCS

(Helicobacter
pylori) 		PF00924
(MS_channel) 		4 LEU A 189
PHE A 224
ILE A 187
ILE A 214
 None
 1.08A 5dzk4-4hw9A:
undetectable
5dzkg-4hw9A:
undetectable
5dzkm-4hw9A:
undetectable
5dzkn-4hw9A:
undetectable		 5dzk4-4hw9A:
6.25
5dzkg-4hw9A:
21.41
5dzkm-4hw9A:
21.63
5dzkn-4hw9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imd N-ACETYLNEURAMINATE
LYASE

(Pasteurella
multocida) 		PF00701
(DHDPS) 		4 LEU A 184
PHE A   8
ILE A 134
ILE A  77
 EDO  A 302 ( 4.8A)
None
None
None
 1.05A 5dzk4-4imdA:
undetectable
5dzkg-4imdA:
3.1
5dzkm-4imdA:
2.5
5dzkn-4imdA:
2.4		 5dzk4-4imdA:
16.67
5dzkg-4imdA:
23.29
5dzkm-4imdA:
23.69
5dzkn-4imdA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j5u SERINE
HYDROXYMETHYLTRANSFE
RASE

(Rickettsia
rickettsii) 		PF00464
(SHMT) 		4 LEU A 415
PHE A 373
ILE A 413
ILE A  30
 None
 0.87A 5dzk4-4j5uA:
undetectable
5dzkg-4j5uA:
undetectable
5dzkm-4j5uA:
undetectable
5dzkn-4j5uA:
undetectable		 5dzk4-4j5uA:
3.92
5dzkg-4j5uA:
21.34
5dzkm-4j5uA:
20.00
5dzkn-4j5uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9a PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1393C

(Streptococcus
mutans) 		no annotation 4 LEU A  96
PHE A  29
ARG A  21
ILE A  55
 None
 1.03A 5dzk4-4l9aA:
undetectable
5dzkg-4l9aA:
1.8
5dzkm-4l9aA:
1.8
5dzkn-4l9aA:
undetectable		 5dzk4-4l9aA:
0.68
5dzkg-4l9aA:
23.05
5dzkm-4l9aA:
22.11
5dzkn-4l9aA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nul FLAVODOXIN

(Clostridium
beijerinckii) 		PF00258
(Flavodoxin_1) 		4 LEU A  84
PHE A 131
ILE A  50
ILE A 135
 None
 1.01A 5dzk4-4nulA:
undetectable
5dzkg-4nulA:
undetectable
5dzkm-4nulA:
undetectable
5dzkn-4nulA:
undetectable		 5dzk4-4nulA:
4.55
5dzkg-4nulA:
21.33
5dzkm-4nulA:
22.66
5dzkn-4nulA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o38 CYCLIN-G-ASSOCIATED
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 253
PHE A 258
ARG A 293
ILE A 278
 None
 1.06A 5dzk4-4o38A:
undetectable
5dzkg-4o38A:
undetectable
5dzkm-4o38A:
undetectable
5dzkn-4o38A:
undetectable		 5dzk4-4o38A:
3.17
5dzkg-4o38A:
19.76
5dzkm-4o38A:
21.79
5dzkn-4o38A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5h PHENYLACETALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 LEU A 215
PHE A 131
ILE A 216
ILE A 187
 None
 0.86A 5dzk4-4o5hA:
undetectable
5dzkg-4o5hA:
2.9
5dzkm-4o5hA:
undetectable
5dzkn-4o5hA:
undetectable		 5dzk4-4o5hA:
10.00
5dzkg-4o5hA:
17.73
5dzkm-4o5hA:
17.03
5dzkn-4o5hA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p37 PUTATIVE POLY(A)
POLYMERASE CATALYTIC
SUBUNIT

(Megavirus
chiliensis) 		no annotation 4 LEU B 398
ARG B 256
ILE B 255
ILE B 281
 None
 1.09A 5dzk4-4p37B:
undetectable
5dzkg-4p37B:
undetectable
5dzkm-4p37B:
undetectable
5dzkn-4p37B:
undetectable		 5dzk4-4p37B:
0.98
5dzkg-4p37B:
16.42
5dzkm-4p37B:
16.48
5dzkn-4p37B:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qx5 CGMP-DEPENDENT
PROTEIN KINASE 1

(Homo sapiens) 		PF00027
(cNMP_binding) 		4 LEU A 329
PHE A 237
ILE A 331
ILE A 340
 None
 1.02A 5dzk4-4qx5A:
undetectable
5dzkg-4qx5A:
undetectable
5dzkm-4qx5A:
undetectable
5dzkn-4qx5A:
undetectable		 5dzk4-4qx5A:
6.90
5dzkg-4qx5A:
21.72
5dzkm-4qx5A:
22.93
5dzkn-4qx5A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s10 GELSOLIN

(Homo sapiens) 		PF00626
(Gelsolin) 		4 LEU C 191
ARG C 225
ILE C 197
ILE C 220
 None
 0.77A 5dzk4-4s10C:
undetectable
5dzkg-4s10C:
undetectable
5dzkm-4s10C:
undetectable
5dzkn-4s10C:
undetectable		 5dzk4-4s10C:
6.06
5dzkg-4s10C:
18.69
5dzkm-4s10C:
20.42
5dzkn-4s10C:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s2m BETA-LACTAMASE

(Enterobacter
cloacae) 		PF00905
(Transpeptidase) 		4 LEU A  81
ARG A 134
ILE A  79
ILE A 130
 None
 1.09A 5dzk4-4s2mA:
undetectable
5dzkg-4s2mA:
undetectable
5dzkm-4s2mA:
undetectable
5dzkn-4s2mA:
undetectable		 5dzk4-4s2mA:
1.74
5dzkg-4s2mA:
20.72
5dzkm-4s2mA:
20.80
5dzkn-4s2mA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcw RIBOSOMAL SILENCING
FACTOR RSFS

(Mycobacterium
tuberculosis) 		PF02410
(RsfS) 		4 LEU A 107
PHE A  41
ARG A  99
ILE A  43
 None
 1.10A 5dzk4-4wcwA:
undetectable
5dzkg-4wcwA:
undetectable
5dzkm-4wcwA:
undetectable
5dzkn-4wcwA:
undetectable		 5dzk4-4wcwA:
2.38
5dzkg-4wcwA:
23.61
5dzkm-4wcwA:
21.76
5dzkn-4wcwA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY

(Trichoderma
reesei) 		PF13426
(PAS_9) 		4 PHE A 119
ARG A 133
ILE A 112
ILE A 130
 None
 1.05A 5dzk4-4wujA:
undetectable
5dzkg-4wujA:
undetectable
5dzkm-4wujA:
undetectable
5dzkn-4wujA:
undetectable		 5dzk4-4wujA:
10.53
5dzkg-4wujA:
25.23
5dzkm-4wujA:
26.11
5dzkn-4wujA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xn3 TAIL SPIKE PROTEIN

(Salmonella
virus HK620) 		no annotation 4 LEU A 588
PHE A 616
ILE A 587
ILE A 600
 None
 1.06A 5dzk4-4xn3A:
undetectable
5dzkg-4xn3A:
undetectable
5dzkm-4xn3A:
undetectable
5dzkn-4xn3A:
1.3		 5dzk4-4xn3A:
5.13
5dzkg-4xn3A:
16.84
5dzkm-4xn3A:
16.08
5dzkn-4xn3A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhj G PROTEIN-COUPLED
RECEPTOR KINASE 4

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 LEU A 296
PHE A 449
ILE A 376
ILE A 420
 None
 0.99A 5dzk4-4yhjA:
undetectable
5dzkg-4yhjA:
undetectable
5dzkm-4yhjA:
undetectable
5dzkn-4yhjA:
undetectable		 5dzk4-4yhjA:
16.67
5dzkg-4yhjA:
15.48
5dzkm-4yhjA:
15.04
5dzkn-4yhjA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9b POLYHEDRIN

(Cypovirus 1) 		PF05865
(Cypo_polyhedrin) 		4 PHE A  65
ARG A 209
ILE A  61
ILE A  51
 None
 1.09A 5dzk4-5a9bA:
undetectable
5dzkg-5a9bA:
undetectable
5dzkm-5a9bA:
undetectable
5dzkn-5a9bA:
undetectable		 5dzk4-5a9bA:
1.87
5dzkg-5a9bA:
19.01
5dzkm-5a9bA:
22.32
5dzkn-5a9bA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bop OCTARELLIN V.1

(synthetic
construct) 		no annotation 4 LEU B   4
PHE B 139
ILE B 112
ILE B 153
 None
 1.05A 5dzk4-5bopB:
undetectable
5dzkg-5bopB:
1.5
5dzkm-5bopB:
undetectable
5dzkn-5bopB:
undetectable		 5dzk4-5bopB:
4.08
5dzkg-5bopB:
22.58
5dzkm-5bopB:
23.01
5dzkn-5bopB:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cya TUBULIN-SPECIFIC
CHAPERONE C

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 190
PHE A 220
ILE A 212
ILE A 230
 None
 0.89A 5dzk4-5cyaA:
undetectable
5dzkg-5cyaA:
1.7
5dzkm-5cyaA:
1.7
5dzkn-5cyaA:
1.6		 5dzk4-5cyaA:
0.75
5dzkg-5cyaA:
21.94
5dzkm-5cyaA:
24.10
5dzkn-5cyaA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eeb ALDEHYDE
DEHYDROGENASE

(Pyrobaculum
ferrireducens) 		PF00171
(Aldedh) 		4 LEU A 260
PHE A 434
ILE A 261
ILE A 425
 None
 0.79A 5dzk4-5eebA:
undetectable
5dzkg-5eebA:
undetectable
5dzkm-5eebA:
undetectable
5dzkn-5eebA:
undetectable		 5dzk4-5eebA:
0.56
5dzkg-5eebA:
18.33
5dzkm-5eebA:
18.74
5dzkn-5eebA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5faf GELSOLIN

(Homo sapiens) 		PF00626
(Gelsolin) 		4 LEU A 191
ARG A 225
ILE A 197
ILE A 220
 None
None
None
GOL  A 302 (-4.3A)
 0.70A 5dzk4-5fafA:
undetectable
5dzkg-5fafA:
undetectable
5dzkm-5fafA:
undetectable
5dzkn-5fafA:
undetectable		 5dzk4-5fafA:
4.55
5dzkg-5fafA:
19.63
5dzkm-5fafA:
19.80
5dzkn-5fafA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h0r VP4 PROTEIN

(Cypovirus 1) 		no annotation 4 LEU G 294
PHE G 286
ILE G 510
ILE G 307
 None
 0.94A 5dzk4-5h0rG:
undetectable
5dzkg-5h0rG:
undetectable
5dzkm-5h0rG:
undetectable
5dzkn-5h0rG:
undetectable		 5dzk4-5h0rG:
0.68
5dzkg-5h0rG:
17.65
5dzkm-5h0rG:
15.86
5dzkn-5h0rG:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Homo sapiens;
Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 LEU A 771
PHE A 787
ILE A 768
ILE A 785
 None
 0.99A 5dzk4-5i4eA:
undetectable
5dzkg-5i4eA:
undetectable
5dzkm-5i4eA:
undetectable
5dzkn-5i4eA:
undetectable		 5dzk4-5i4eA:
1.04
5dzkg-5i4eA:
13.87
5dzkm-5i4eA:
11.46
5dzkn-5i4eA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsj KINETOCHORE-ASSOCIAT
ED PROTEIN DSN1
HOMOLOG
KINETOCHORE-ASSOCIAT
ED PROTEIN NSL1
HOMOLOG

(Homo sapiens;
Homo sapiens) 		PF08202
(MIS13)
no annotation 		4 LEU N 148
ARG D 242
ILE N 147
ILE D 239
 None
 1.06A 5dzk4-5lsjN:
undetectable
5dzkg-5lsjN:
undetectable
5dzkm-5lsjN:
undetectable
5dzkn-5lsjN:
undetectable		 5dzk4-5lsjN:
0.86
5dzkg-5lsjN:
18.36
5dzkm-5lsjN:
20.11
5dzkn-5lsjN:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ti8 AMINOTRANSFERASE

(Pseudomonas sp.
M1) 		PF00202
(Aminotran_3) 		4 LEU A 292
PHE A 274
ILE A 338
ILE A 108
 None
 1.03A 5dzk4-5ti8A:
undetectable
5dzkg-5ti8A:
2.4
5dzkm-5ti8A:
1.8
5dzkn-5ti8A:
undetectable		 5dzk4-5ti8A:
0.21
5dzkg-5ti8A:
20.42
5dzkm-5ti8A:
19.79
5dzkn-5ti8A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tz6 CURJ

(Moorea
producens) 		PF14765
(PS-DH) 		4 LEU A 994
PHE A1042
ILE A 992
ILE A1013
 None
 1.02A 5dzk4-5tz6A:
undetectable
5dzkg-5tz6A:
undetectable
5dzkm-5tz6A:
undetectable
5dzkn-5tz6A:
undetectable		 5dzk4-5tz6A:
3.45
5dzkg-5tz6A:
20.13
5dzkm-5tz6A:
22.76
5dzkn-5tz6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uou 2-OXO-4-HYDROXY-4-CA
RBOXY-5-UREIDOIMIDAZ
OLINE (OHCU)
DECARBOXYLASE

(Klebsiella
pneumoniae) 		PF09349
(OHCU_decarbox) 		4 LEU A 130
PHE A 117
ILE A 129
ILE A 119
 None
 1.01A 5dzk4-5uouA:
undetectable
5dzkg-5uouA:
undetectable
5dzkm-5uouA:
undetectable
5dzkn-5uouA:
undetectable		 5dzk4-5uouA:
4.44
5dzkg-5uouA:
23.85
5dzkm-5uouA:
26.91
5dzkn-5uouA:
26.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uou 2-OXO-4-HYDROXY-4-CA
RBOXY-5-UREIDOIMIDAZ
OLINE (OHCU)
DECARBOXYLASE

(Klebsiella
pneumoniae) 		PF09349
(OHCU_decarbox) 		4 PHE A 117
ARG A 124
ILE A 129
ILE A 119
 None
 1.01A 5dzk4-5uouA:
undetectable
5dzkg-5uouA:
undetectable
5dzkm-5uouA:
undetectable
5dzkn-5uouA:
undetectable		 5dzk4-5uouA:
4.44
5dzkg-5uouA:
23.85
5dzkm-5uouA:
26.91
5dzkn-5uouA:
26.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wln TYPE II SECRETION
SYSTEM PROTEIN D

(Pseudomonas
aeruginosa) 		no annotation 4 LEU G 414
ARG G 505
ILE G 333
ILE G 485
 None
 1.08A 5dzk4-5wlnG:
undetectable
5dzkg-5wlnG:
undetectable
5dzkm-5wlnG:
undetectable
5dzkn-5wlnG:
undetectable		 5dzk4-5wlnG:
0.66
5dzkg-5wlnG:
16.85
5dzkm-5wlnG:
15.70
5dzkn-5wlnG:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhq APOLIPOPROTEIN
N-ACYLTRANSFERASE

(Escherichia
coli) 		PF00795
(CN_hydrolase) 		4 LEU A 235
ARG A 467
ILE A 231
ILE A 248
 None
 1.04A 5dzk4-5xhqA:
undetectable
5dzkg-5xhqA:
undetectable
5dzkm-5xhqA:
undetectable
5dzkn-5xhqA:
undetectable		 5dzk4-5xhqA:
13.33
5dzkg-5xhqA:
18.40
5dzkm-5xhqA:
18.54
5dzkn-5xhqA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yhb POLYHEDRIN

(Cypovirus 1) 		no annotation 4 PHE A  65
ARG A 209
ILE A  61
ILE A  51
 None
PD  A 304 ( 2.6A)
None
None
 1.09A 5dzk4-5yhbA:
undetectable
5dzkg-5yhbA:
undetectable
5dzkm-5yhbA:
undetectable
5dzkn-5yhbA:
undetectable		 5dzk4-5yhbA:
2.19
5dzkg-5yhbA:
19.92
5dzkm-5yhbA:
22.43
5dzkn-5yhbA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zba -

(-) 		no annotation 4 LEU B  97
ARG B 137
ILE B  95
ILE B 139
 None
 0.98A 5dzk4-5zbaB:
undetectable
5dzkg-5zbaB:
undetectable
5dzkm-5zbaB:
undetectable
5dzkn-5zbaB:
undetectable		 5dzk4-5zbaB:
undetectable
5dzkg-5zbaB:
undetectable
5dzkm-5zbaB:
undetectable
5dzkn-5zbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4o GLUTATHIONE
REDUCTASE

(Enterococcus
faecalis) 		no annotation 4 LEU A 135
PHE A 116
ILE A   7
ILE A 122
 None
 1.05A 5dzk4-6b4oA:
undetectable
5dzkg-6b4oA:
undetectable
5dzkm-6b4oA:
undetectable
5dzkn-6b4oA:
undetectable		 5dzk4-6b4oA:
5.88
5dzkg-6b4oA:
18.95
5dzkm-6b4oA:
18.38
5dzkn-6b4oA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2

(Mus musculus) 		no annotation 4 LEU B 289
ARG B 284
ILE B 273
ILE B 256
 None
 1.05A 5dzk4-6cimB:
undetectable
5dzkg-6cimB:
undetectable
5dzkm-6cimB:
undetectable
5dzkn-6cimB:
undetectable		 5dzk4-6cimB:
undetectable
5dzkg-6cimB:
undetectable
5dzkm-6cimB:
undetectable
5dzkn-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cp7 ATP SYNTHASE SUBUNIT
F, MITOCHONDRIAL
ATP SYNTHASE SUBUNIT
A

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
no annotation 		4 LEU X  38
PHE U  69
ILE X  35
ILE U  73
 None
 1.06A 5dzk4-6cp7X:
undetectable
5dzkg-6cp7X:
undetectable
5dzkm-6cp7X:
undetectable
5dzkn-6cp7X:
undetectable		 5dzk4-6cp7X:
undetectable
5dzkg-6cp7X:
undetectable
5dzkm-6cp7X:
undetectable
5dzkn-6cp7X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ek4 PAXB

(Photorhabdus
luminescens) 		no annotation 4 LEU A  32
ARG A 295
ILE A  29
ILE A  50
 None
 1.04A 5dzk4-6ek4A:
undetectable
5dzkg-6ek4A:
undetectable
5dzkm-6ek4A:
undetectable
5dzkn-6ek4A:
undetectable		 5dzk4-6ek4A:
undetectable
5dzkg-6ek4A:
undetectable
5dzkm-6ek4A:
undetectable
5dzkn-6ek4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fea NITROGENASE PROTEIN
ALPHA CHAIN

(Azotobacter
vinelandii) 		no annotation 4 PHE A 433
ARG A 292
ILE A 291
ILE A 308
 None
 1.08A 5dzk4-6feaA:
undetectable
5dzkg-6feaA:
undetectable
5dzkm-6feaA:
undetectable
5dzkn-6feaA:
undetectable		 5dzk4-6feaA:
undetectable
5dzkg-6feaA:
undetectable
5dzkm-6feaA:
undetectable
5dzkn-6feaA:
undetectable