SIMILAR PATTERNS OF AMINO ACIDS FOR 5DV4_A_NMYA601_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bpo PROTEIN (CLATHRIN)

(Rattus
norvegicus) 		PF01394
(Clathrin_propel)
PF09268
(Clathrin-link)
PF13838
(Clathrin_H_link) 		3 GLU A 133
TRP A 130
ASN A  74
 None
 1.11A 5dv4A-1bpoA:
undetectable		 5dv4A-1bpoA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7t BETA-N-ACETYLHEXOSAM
INIDASE

(Serratia
marcescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF03173
(CHB_HEX)
PF03174
(CHB_HEX_C) 		3 GLU A 769
TRP A 726
ASN A 706
 None
 1.15A 5dv4A-1c7tA:
1.3		 5dv4A-1c7tA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpy SERINE
CARBOXYPEPTIDASE

(Saccharomyces
cerevisiae) 		PF00450
(Peptidase_S10) 		3 GLU A 198
TRP A 343
ASN A 394
 None
 1.15A 5dv4A-1cpyA:
0.0		 5dv4A-1cpyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gp1 GLUTATHIONE
PEROXIDASE

(Bos taurus) 		PF00255
(GSHPx) 		3 GLU A 161
TRP A 158
ASN A 114
 None
SE7  A  45 ( 4.4A)
None
 1.00A 5dv4A-1gp1A:
undetectable		 5dv4A-1gp1A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h39 SQUALENE--HOPENE
CYCLASE

(Alicyclobacillus
acidocaldarius) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		3 GLU A 446
TRP A 489
ASN A 492
 None
R03  A 800 (-4.7A)
None
 0.70A 5dv4A-1h39A:
undetectable		 5dv4A-1h39A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itu RENAL DIPEPTIDASE

(Homo sapiens) 		PF01244
(Peptidase_M19) 		3 GLU A 125
TRP A 162
ASN A 250
 ZN  A 401 ( 2.5A)
None
CIL  A 451 ( 4.7A)
 0.58A 5dv4A-1ituA:
0.6		 5dv4A-1ituA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js1 TRANSCARBAMYLASE

(Bacteroides
fragilis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 GLU X 208
TRP X 173
ASN X 245
 None
 0.91A 5dv4A-1js1X:
undetectable		 5dv4A-1js1X:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLU A  11
TRP A 211
ASN A  92
 None
 0.67A 5dv4A-1kcwA:
1.2		 5dv4A-1kcwA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLU A 721
TRP A 910
ASN A 807
 None
 0.82A 5dv4A-1kcwA:
1.2		 5dv4A-1kcwA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF00266
(Aminotran_5) 		3 GLU A  40
TRP A 229
ASN A 235
 None
 1.13A 5dv4A-1m32A:
0.0		 5dv4A-1m32A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 GLU H  96
TRP H  50
ASN H  31
 None
 0.92A 5dv4A-1ncbH:
undetectable		 5dv4A-1ncbH:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvb BETA-GLYCOSIDASE

(Thermosphaera
aggregans) 		PF00232
(Glyco_hydro_1) 		3 GLU A  82
TRP A  83
ASN A 148
 None
 0.75A 5dv4A-1qvbA:
undetectable		 5dv4A-1qvbA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r77 CELL WALL TARGETING
DOMAIN OF
GLYCYLGLYCINE
ENDOPEPTIDASE ALE-1

(Staphylococcus
capitis) 		PF08460
(SH3_5) 		3 GLU A 320
TRP A 329
ASN A 274
 None
 1.15A 5dv4A-1r77A:
undetectable		 5dv4A-1r77A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s14 TOPOISOMERASE IV
SUBUNIT B

(Escherichia
coli) 		PF02518
(HATPase_c) 		3 GLU A1171
TRP A1168
ASN A1143
 None
 1.06A 5dv4A-1s14A:
undetectable		 5dv4A-1s14A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s16 TOPOISOMERASE IV
SUBUNIT B

(Escherichia
coli) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		3 GLU A1171
TRP A1168
ASN A1143
 None
 1.09A 5dv4A-1s16A:
undetectable		 5dv4A-1s16A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwi BETA-GALACTOSIDASE

(Sulfolobus
solfataricus) 		PF00232
(Glyco_hydro_1) 		3 GLU A  83
TRP A  84
ASN A 147
 None
 0.70A 5dv4A-1uwiA:
undetectable		 5dv4A-1uwiA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wch PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 13

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 GLU A2313
TRP A2376
ASN A2372
 None
None
PO4  A3480 (-2.8A)
 1.06A 5dv4A-1wchA:
undetectable		 5dv4A-1wchA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 GLU A 822
TRP A 828
ASN A 742
 None
 1.14A 5dv4A-1wz2A:
undetectable		 5dv4A-1wz2A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xyz 1,4-BETA-D-XYLAN-XYL
ANOHYDROLASE

(Ruminiclostridium
thermocellum) 		PF00331
(Glyco_hydro_10) 		3 GLU A 639
TRP A 640
ASN A 687
 None
 1.13A 5dv4A-1xyzA:
undetectable		 5dv4A-1xyzA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aey FRUCTAN
1-EXOHYDROLASE IIA

(Cichorium
intybus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 GLU A 304
TRP A 307
ASN A 502
 None
 1.13A 5dv4A-2aeyA:
undetectable		 5dv4A-2aeyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dlw DOCKING PROTEIN 2,
ISOFORM A

(Homo sapiens) 		PF02174
(IRS) 		3 GLU A  81
TRP A  54
ASN A  83
 None
 1.15A 5dv4A-2dlwA:
undetectable		 5dv4A-2dlwA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dxb THIOCYANATE
HYDROLASE SUBUNIT
GAMMA

(Thiobacillus
thioparus) 		PF02979
(NHase_alpha) 		3 GLU C 165
TRP C 158
ASN C 150
 None
 1.15A 5dv4A-2dxbC:
undetectable		 5dv4A-2dxbC:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ej4 ZINC FINGER PROTEIN
ZIC 3

(Homo sapiens) 		PF00096
(zf-C2H2) 		3 GLU A  21
TRP A  18
ASN A  57
 None
 1.14A 5dv4A-2ej4A:
undetectable		 5dv4A-2ej4A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8a GLUTATHIONE
PEROXIDASE 1

(Homo sapiens) 		PF00255
(GSHPx) 		3 GLU A 163
TRP A 160
ASN A 116
 None
MLA  A 501 (-4.1A)
None
 1.01A 5dv4A-2f8aA:
undetectable		 5dv4A-2f8aA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjt RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE PTPRO

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 GLU A1041
TRP A1100
ASN A1096
 None
 1.13A 5dv4A-2gjtA:
undetectable		 5dv4A-2gjtA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2he3 GLUTATHIONE
PEROXIDASE 2

(Homo sapiens) 		PF00255
(GSHPx) 		3 GLU A 155
TRP A 152
ASN A 108
 None
 1.02A 5dv4A-2he3A:
undetectable		 5dv4A-2he3A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3y EPIDIDYMAL SECRETORY
GLUTATHIONE
PEROXIDASE

(Homo sapiens) 		PF00255
(GSHPx) 		3 GLU A 184
TRP A 181
ASN A 141
 None
EDO  A 221 ( 3.7A)
None
 0.88A 5dv4A-2i3yA:
undetectable		 5dv4A-2i3yA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nna MHC CLASS II ANTIGEN

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		3 GLU B 187
TRP B 188
ASN B 134
 None
 1.09A 5dv4A-2nnaB:
undetectable		 5dv4A-2nnaB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p24 H-2 CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A-U BETA
CHAIN

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		3 GLU B 287
TRP B 288
ASN B 234
 None
 1.05A 5dv4A-2p24B:
undetectable		 5dv4A-2p24B:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r37 GLUTATHIONE
PEROXIDASE 3

(Homo sapiens) 		PF00255
(GSHPx) 		3 GLU A 184
TRP A 181
ASN A 141
 None
CL  A   1 (-4.7A)
None
 0.83A 5dv4A-2r37A:
undetectable		 5dv4A-2r37A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2sas SARCOPLASMIC
CALCIUM-BINDING
PROTEIN

(Branchiostoma
lanceolatum) 		PF13833
(EF-hand_8) 		3 GLU A  32
TRP A  62
ASN A  21
 None
None
CA  A 186 ( 2.7A)
 1.11A 5dv4A-2sasA:
undetectable		 5dv4A-2sasA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywa HYPOTHETICAL PROTEIN
TTHA0048

(Thermus
thermophilus) 		PF08780
(NTase_sub_bind) 		3 GLU A  32
TRP A  39
ASN A  83
 None
 1.07A 5dv4A-2ywaA:
undetectable		 5dv4A-2ywaA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj9 AMPC

(Escherichia
coli) 		PF00144
(Beta-lactamase) 		3 GLU A 272
TRP A 312
ASN A 346
 IPA  A 362 (-4.3A)
None
None
 0.98A 5dv4A-2zj9A:
undetectable		 5dv4A-2zj9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Bifidobacterium
longum) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		3 GLU A 800
TRP A 823
ASN A 720
 None
MPD  A1696 (-4.1A)
None
 0.80A 5dv4A-2zxqA:
undetectable		 5dv4A-2zxqA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3akz GLUTAMYL-TRNA
SYNTHETASE 2

(Thermotoga
maritima) 		no annotation 3 GLU B 339
TRP B 343
ASN B 324
 None
 1.04A 5dv4A-3akzB:
undetectable		 5dv4A-3akzB:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4u CARBOXYPEPTIDASE B2
CARBOXYPEPTIDASE
INHIBITOR

(Bos taurus;
Rhipicephalus
bursa) 		PF00246
(Peptidase_M14)
PF10468
(Inhibitor_I68) 		3 GLU A  72
TRP B  73
ASN A 144
 ZN  A 309 (-2.1A)
None
ACT  A 601 (-3.8A)
 1.02A 5dv4A-3d4uA:
undetectable		 5dv4A-3d4uA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fv5 DNA TOPOISOMERASE 4
SUBUNIT B

(Escherichia
coli) 		PF02518
(HATPase_c) 		3 GLU A 171
TRP A 168
ASN A 143
 None
 1.04A 5dv4A-3fv5A:
undetectable		 5dv4A-3fv5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gpi NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E

(Methylobacillus
flagellatus) 		PF13460
(NAD_binding_10) 		3 GLU A 116
TRP A 118
ASN A 244
 None
None
EDO  A 286 (-3.3A)
 1.16A 5dv4A-3gpiA:
undetectable		 5dv4A-3gpiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzs UNCHARACTERIZED SUSD
SUPERFAMILY PROTEIN

(Bacteroides
fragilis) 		PF12741
(SusD-like) 		3 GLU A 468
TRP A 466
ASN A 461
 None
None
ACT  A   8 (-3.6A)
 1.06A 5dv4A-3gzsA:
undetectable		 5dv4A-3gzsA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
13
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'

(Sulfolobus
solfataricus) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF12136
(RNA_pol_Rpo13) 		3 GLU Y  76
TRP A 125
ASN A 119
 None
 1.14A 5dv4A-3hkzY:
undetectable		 5dv4A-3hkzY:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7u AP4A HYDROLASE

(Aquifex
aeolicus) 		PF00293
(NUDIX) 		3 GLU A  51
TRP A  96
ASN A  33
 None
None
CL  A 148 ( 4.4A)
 1.10A 5dv4A-3i7uA:
undetectable		 5dv4A-3i7uA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3il4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Enterococcus
faecalis) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		3 GLU A  37
TRP A  38
ASN A  25
 None
ACO  A 401 (-3.6A)
None
 1.14A 5dv4A-3il4A:
undetectable		 5dv4A-3il4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ive NUCLEOTIDASE

(Escherichia
coli) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		3 GLU A 337
TRP A  44
ASN A 376
 None
 1.05A 5dv4A-3iveA:
5.1		 5dv4A-3iveA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jvd TRANSCRIPTIONAL
REGULATORS

(Corynebacterium
glutamicum) 		PF13377
(Peripla_BP_3) 		3 GLU A  81
TRP A 271
ASN A  76
 None
 0.78A 5dv4A-3jvdA:
undetectable		 5dv4A-3jvdA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg3 ISOCITRATE LYASE

(Yersinia pestis) 		PF00463
(ICL) 		3 GLU A 160
TRP A  94
ASN A 101
 None
 1.10A 5dv4A-3lg3A:
undetectable		 5dv4A-3lg3A:
23.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ngo CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		3 GLU A 240
TRP A 363
ASN A 479
 MG  A 557 (-2.6A)
None
None
 0.16A 5dv4A-3ngoA:
57.3		 5dv4A-3ngoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE

(Pseudomonas
aeruginosa) 		PF01048
(PNP_UDP_1) 		3 GLU A  41
TRP A  85
ASN A  79
 None
 1.03A 5dv4A-3ozbA:
undetectable		 5dv4A-3ozbA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r3t 30S RIBOSOMAL
PROTEIN S6

(Bacillus
anthracis) 		PF01250
(Ribosomal_S6) 		3 GLU A   5
TRP A  43
ASN A  39
 None
 1.14A 5dv4A-3r3tA:
undetectable		 5dv4A-3r3tA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5q PUTATIVE
GLYCOSYLHYDROLASE

(Parabacteroides
distasonis) 		PF06439
(DUF1080) 		3 GLU A 103
TRP A 121
ASN A  84
 None
 1.02A 5dv4A-3s5qA:
undetectable		 5dv4A-3s5qA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Shewanella
pealeana) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 283
TRP A 111
ASN A  84
 None
 1.00A 5dv4A-3sjnA:
undetectable		 5dv4A-3sjnA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT

(uncultured
archaeon) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		3 GLU A 488
TRP A 522
ASN A 518
 None
 1.00A 5dv4A-3sqgA:
undetectable		 5dv4A-3sqgA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5f BETA-GALACTOSIDASE

(Solanum
lycopersicum) 		PF01301
(Glyco_hydro_35) 		3 GLU A  72
TRP A 252
ASN A 180
 CL  A 807 (-4.5A)
EPE  A 804 (-4.0A)
None
 1.04A 5dv4A-3w5fA:
undetectable		 5dv4A-3w5fA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq1 ENDOGLUCANASE A

(Pyrococcus
furiosus) 		PF01670
(Glyco_hydro_12) 		3 GLU A 127
TRP A  84
ASN A 136
 BGC  A 413 ( 4.9A)
BGC  A 413 (-3.8A)
BGC  A 412 ( 3.9A)
 1.13A 5dv4A-3wq1A:
undetectable		 5dv4A-3wq1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq8 BETA-GLUCOSIDASE

(Pyrococcus
furiosus) 		PF00232
(Glyco_hydro_1) 		3 GLU A  81
TRP A  31
ASN A 206
 None
 1.03A 5dv4A-3wq8A:
undetectable		 5dv4A-3wq8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq8 BETA-GLUCOSIDASE

(Pyrococcus
furiosus) 		PF00232
(Glyco_hydro_1) 		3 GLU A  81
TRP A  82
ASN A 147
 None
 0.96A 5dv4A-3wq8A:
undetectable		 5dv4A-3wq8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsu BETA-MANNANASE

(Streptomyces
thermolilacinus) 		PF00150
(Cellulase) 		3 GLU A 178
TRP A 188
ASN A 174
 NA  A 402 (-2.8A)
None
None
 1.14A 5dv4A-3wsuA:
2.2		 5dv4A-3wsuA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ap5 GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2

(Homo sapiens) 		PF10250
(O-FucT) 		3 GLU A 232
TRP A 234
ASN A 116
 None
 1.05A 5dv4A-4ap5A:
undetectable		 5dv4A-4ap5A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bub UDP-N-ACETYLMURAMOYL
-L-ALANYL-D-GLUTAMAT
E--LD-LYSINE LIGASE

(Thermotoga
maritima) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 GLU A  97
TRP A 100
ASN A   9
 None
 0.95A 5dv4A-4bubA:
undetectable		 5dv4A-4bubA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d8p PEPTIDE FROM
GAMMA-GLIADIN,HLA
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DQ BETA 1
CHAIN

(Homo sapiens;
Triticum
aestivum) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		3 GLU B 187
TRP B 188
ASN B 134
 None
 1.08A 5dv4A-4d8pB:
undetectable		 5dv4A-4d8pB:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffy DENV1-E111 SINGLE
CHAIN VARIABLE
FRAGMENT (HEAVY
CHAIN)
DENV1-E111 SINGLE
CHAIN VARIABLE
FRAGMENT (LIGHT
CHAIN)

(Mus musculus) 		PF07686
(V-set) 		3 GLU H  46
TRP H  47
ASN L   1
 None
 1.15A 5dv4A-4ffyH:
undetectable		 5dv4A-4ffyH:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fin ETTA (YJJK) ABCF
FAMILY PROTEIN

(Escherichia
coli) 		PF00005
(ABC_tran)
PF12848
(ABC_tran_Xtn) 		3 GLU A 274
TRP A 275
ASN A 485
 None
 1.08A 5dv4A-4finA:
undetectable		 5dv4A-4finA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ha4 BETA-GALACTOSIDASE

(Acidilobus
saccharovorans) 		PF00232
(Glyco_hydro_1) 		3 GLU A  84
TRP A  34
ASN A 207
 None
None
GOL  A 505 (-2.9A)
 1.03A 5dv4A-4ha4A:
2.2		 5dv4A-4ha4A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ha4 BETA-GALACTOSIDASE

(Acidilobus
saccharovorans) 		PF00232
(Glyco_hydro_1) 		3 GLU A  84
TRP A  85
ASN A 149
 None
 0.79A 5dv4A-4ha4A:
2.2		 5dv4A-4ha4A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 GLU A 386
TRP A 384
ASN A 573
 None
 1.02A 5dv4A-4hozA:
undetectable		 5dv4A-4hozA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hq1 PROBABLE RECEPTOR
PROTEIN KINASE TMK1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		3 GLU A 141
TRP A  97
ASN A 168
 None
 1.09A 5dv4A-4hq1A:
undetectable		 5dv4A-4hq1A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3o OUTER MEMBRANE USHER
PROTEIN FIMD

(Escherichia
coli) 		PF00577
(Usher)
PF13953
(PapC_C)
PF13954
(PapC_N) 		3 GLU D 131
TRP D 133
ASN D 122
 None
 1.13A 5dv4A-4j3oD:
undetectable		 5dv4A-4j3oD:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN

(Archaeoglobus
fulgidus) 		PF01699
(Na_Ca_ex) 		3 GLU A 255
TRP A 116
ASN A 284
 None
 1.04A 5dv4A-4kppA:
undetectable		 5dv4A-4kppA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxb GLUTAMYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLU A 236
TRP A 133
ASN A  98
 None
 0.65A 5dv4A-4kxbA:
undetectable		 5dv4A-4kxbA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbu SIMILAR TO
N-ACETYLTRANSFERASE

(Staphylococcus
aureus) 		PF13420
(Acetyltransf_4) 		3 GLU A  37
TRP A  41
ASN A  18
 None
 1.15A 5dv4A-4mbuA:
undetectable		 5dv4A-4mbuA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0r PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
vulgatus) 		PF13204
(DUF4038)
PF16586
(DUF5060) 		3 GLU A 391
TRP A 402
ASN A 360
 None
UNL  A 601 ( 4.3A)
None
 1.02A 5dv4A-4n0rA:
undetectable		 5dv4A-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oec GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Thermococcus
kodakarensis) 		PF03009
(GDPD) 		3 GLU A  39
TRP A 207
ASN A 233
 MG  A 401 (-2.6A)
None
None
 0.81A 5dv4A-4oecA:
undetectable		 5dv4A-4oecA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG

(Escherichia
coli;
Tribolium
castaneum) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		3 GLU A  47
TRP A 342
ASN A  14
 None
MAL  A1401 (-3.7A)
MAL  A1401 (-4.6A)
 0.99A 5dv4A-4xaiA:
undetectable		 5dv4A-4xaiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0v 2',5'-PHOSPHODIESTER
ASE 12

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		3 GLU A 351
TRP A 459
ASN A 551
 MG  A 701 (-2.4A)
None
None
 0.37A 5dv4A-4z0vA:
39.5		 5dv4A-4z0vA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
IRON-SULFUR SUBUNIT
PUTATIVE
OXIDOREDUCTASE
MOLYBDOPTERIN-BINDIN
G SUBUNIT

(Sulfurisphaera
tokodaii) 		PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2) 		3 GLU A  11
TRP C  99
ASN A 599
 None
 0.93A 5dv4A-4zohA:
undetectable		 5dv4A-4zohA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
MOLYBDOPTERIN-BINDIN
G SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		3 GLU A 672
TRP A 482
ASN A 297
 MCN  A 801 ( 3.2A)
1PE  A 803 ( 4.0A)
1PE  A 803 (-4.5A)
 0.98A 5dv4A-4zohA:
undetectable		 5dv4A-4zohA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF14492
(EFG_II) 		3 GLU K 802
TRP K 801
ASN K 818
 None
 1.06A 5dv4A-5anbK:
undetectable		 5dv4A-5anbK:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2m PREDICTED PROTEIN

(Nematostella
vectensis) 		PF14517
(Tachylectin) 		3 GLU A  32
TRP A  38
ASN A  14
 None
 1.08A 5dv4A-5c2mA:
undetectable		 5dv4A-5c2mA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb2 PROTEIN SEY1

(Candida
albicans) 		PF05879
(RHD3) 		3 GLU A 125
TRP A  99
ASN A  35
 None
 0.89A 5dv4A-5cb2A:
undetectable		 5dv4A-5cb2A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czw MYROILYSIN

(Myroides
profundi) 		PF01400
(Astacin) 		3 GLU A 143
TRP A  76
ASN A 225
 ZN  A 301 ( 4.2A)
None
None
 0.85A 5dv4A-5czwA:
undetectable		 5dv4A-5czwA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dkx ALPHA
GLUCOSIDASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110) 		3 GLU A 372
TRP A 342
ASN A 587
 None
 1.12A 5dv4A-5dkxA:
undetectable		 5dv4A-5dkxA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fip GH5 CELLULASE

(unidentified) 		PF00150
(Cellulase)
PF03424
(CBM_17_28) 		3 GLU A 316
TRP A 268
ASN A 321
 PEG  A1384 (-4.4A)
PEG  A1387 ( 4.3A)
PEG  A1387 (-3.7A)
 0.83A 5dv4A-5fipA:
undetectable		 5dv4A-5fipA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01547
(SBP_bac_1) 		3 GLU A  75
TRP A 369
ASN A 138
 None
 1.15A 5dv4A-5g5zA:
undetectable		 5dv4A-5g5zA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB

(Mus musculus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 GLU A 380
TRP A 344
ASN A 595
 None
 1.05A 5dv4A-5hjrA:
undetectable		 5dv4A-5hjrA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hos CELLULASE

(Xanthomonas
citri) 		PF00150
(Cellulase) 		3 GLU A 271
TRP A 280
ASN A 264
 None
 1.12A 5dv4A-5hosA:
undetectable		 5dv4A-5hosA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsg PUTATIVE ABC
TRANSPORTER,
NUCLEOTIDE
BINDING/ATPASE
PROTEIN

(Klebsiella
pneumoniae) 		PF13407
(Peripla_BP_4) 		3 GLU A 226
TRP A 250
ASN A 199
 None
 1.08A 5dv4A-5hsgA:
undetectable		 5dv4A-5hsgA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i1w CRMK

(Actinoalloteichus
sp. WH1-2216-6) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 GLU A 301
TRP A 297
ASN A 254
 None
 1.00A 5dv4A-5i1wA:
undetectable		 5dv4A-5i1wA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5leo LYSOSTAPHIN

(Staphylococcaceae) 		PF08460
(SH3_5) 		3 GLU A 451
TRP A 460
ASN A 405
 None
 1.06A 5dv4A-5leoA:
undetectable		 5dv4A-5leoA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqp GLYCOSIDE HYDROLASE
BT_1002

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLU A 565
TRP A 495
ASN A 362
 None
 1.13A 5dv4A-5mqpA:
undetectable		 5dv4A-5mqpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n40 PUTATIVE INVASIN

(Yersinia
pseudotuberculosis) 		PF05689
(DUF823)
PF09134
(Invasin_D3) 		3 GLU A2705
TRP A2748
ASN A2740
 None
 1.00A 5dv4A-5n40A:
undetectable		 5dv4A-5n40A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4l CERULOPLASMIN

(Rattus
norvegicus) 		no annotation 3 GLU A  11
TRP A 210
ASN A  92
 None
 0.92A 5dv4A-5n4lA:
undetectable		 5dv4A-5n4lA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4l CERULOPLASMIN

(Rattus
norvegicus) 		no annotation 3 GLU A 715
TRP A 904
ASN A 801
 None
 0.95A 5dv4A-5n4lA:
undetectable		 5dv4A-5n4lA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndx GLYCOSYL HYDROLASE

(Rhizobium
leguminosarum) 		no annotation 3 GLU A 485
TRP A 456
ASN A 451
 None
 1.08A 5dv4A-5ndxA:
undetectable		 5dv4A-5ndxA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila) 		no annotation 3 GLU A 443
TRP A 436
ASN A 385
 None
 1.04A 5dv4A-5ot4A:
undetectable		 5dv4A-5ot4A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tgt GLUTAMATE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c) 		3 GLU A 337
TRP A 341
ASN A 322
 None
 1.14A 5dv4A-5tgtA:
undetectable		 5dv4A-5tgtA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris) 		no annotation 3 GLU A 124
TRP A 127
ASN A 153
 None
 1.07A 5dv4A-5u6fA:
undetectable		 5dv4A-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xn4 ANTI-CRISPR ACRIIA4

(Listeria
monocytogenes) 		no annotation 3 GLU X  72
TRP X  63
ASN X  35
 None
 1.14A 5dv4A-5xn4X:
undetectable		 5dv4A-5xn4X:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6czs -

(-) 		no annotation 3 GLU A  98
TRP A 142
ASN A 101
 NAG  A 401 (-3.8A)
None
NAG  A 401 (-1.9A)
 1.14A 5dv4A-6czsA:
undetectable		 5dv4A-6czsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eon BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLU A  48
TRP A 261
ASN A 181
 None
GLA  A 801 (-4.1A)
GLA  A 801 (-2.9A)
 1.03A 5dv4A-6eonA:
undetectable		 5dv4A-6eonA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLU A 535
TRP A 390
ASN A 635
 None
 0.96A 5dv4A-6f8zA:
undetectable		 5dv4A-6f8zA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 3 GLU B 497
TRP B 495
ASN B 504
 None
 1.14A 5dv4A-6fosB:
undetectable		 5dv4A-6fosB:
11.43