SIMILAR PATTERNS OF AMINO ACIDS FOR 5DSG_A_0HKA1201_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a81 SYK KINASE

(Homo sapiens) 		PF00017
(SH2) 		3 ASN A 108
LEU A  29
PHE A  16
 None
 0.77A 5dsgA-1a81A:
0.0		 5dsgA-1a81A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a81 SYK KINASE

(Homo sapiens) 		PF00017
(SH2) 		3 ASN A 189
LEU A 183
PHE A 192
 None
 0.73A 5dsgA-1a81A:
0.0		 5dsgA-1a81A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b24 PROTEIN (I-DMOI)

(Desulfurococcus
mucosus) 		PF14528
(LAGLIDADG_3) 		3 ASN A 102
LEU A 145
PHE A 109
 None
 0.67A 5dsgA-1b24A:
0.0		 5dsgA-1b24A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ASN A  50
LEU A  46
PHE A  26
 None
 0.72A 5dsgA-1c30A:
0.0		 5dsgA-1c30A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8l PROTEIN (HOLLIDAY
JUNCTION DNA
HELICASE RUVA)

(Escherichia
coli) 		PF01330
(RuvA_N)
PF14520
(HHH_5) 		3 ASN A 100
LEU A  71
PHE A 140
 None
 0.81A 5dsgA-1d8lA:
0.0		 5dsgA-1d8lA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlc DELTA-ENDOTOXIN
CRYIIIA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 ASN A 618
LEU A 512
PHE A 501
 None
 0.80A 5dsgA-1dlcA:
2.9		 5dsgA-1dlcA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ehk BA3-TYPE
CYTOCHROME-C OXIDASE

(Thermus
thermophilus) 		PF00115
(COX1) 		3 ASN A  76
LEU A 117
PHE A  29
 HEM  A 800 (-4.2A)
None
None
 0.45A 5dsgA-1ehkA:
4.2		 5dsgA-1ehkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		3 ASN A 892
LEU A 950
PHE A 971
 None
 0.81A 5dsgA-1g8xA:
1.9		 5dsgA-1g8xA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ga8 GALACTOSYL
TRANSFERASE LGTC

(Neisseria
meningitidis) 		PF01501
(Glyco_transf_8) 		3 ASN A 153
LEU A 115
PHE A 209
 UPF  A 501 (-3.0A)
None
None
 0.58A 5dsgA-1ga8A:
0.0		 5dsgA-1ga8A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gfn MATRIX PORIN OUTER
MEMBRANE PROTEIN F

(Escherichia
coli) 		PF00267
(Porin_1) 		3 ASN A 252
LEU A 324
PHE A 250
 None
 0.71A 5dsgA-1gfnA:
undetectable		 5dsgA-1gfnA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gp1 GLUTATHIONE
PEROXIDASE

(Bos taurus) 		PF00255
(GSHPx) 		3 ASN A  85
LEU A  92
PHE A 108
 None
 0.79A 5dsgA-1gp1A:
undetectable		 5dsgA-1gp1A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h71 SERRALYSIN

(Pseudomonas sp.
'TAC II 18') 		PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		3 ASN P 301
LEU P 233
PHE P  17
 None
 0.81A 5dsgA-1h71P:
undetectable		 5dsgA-1h71P:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iid PEPTIDE
N-MYRISTOYLTRANSFERA
SE

(Saccharomyces
cerevisiae) 		PF01233
(NMT)
PF02799
(NMT_C) 		3 ASN A 404
LEU A 373
PHE A 327
 None
 0.82A 5dsgA-1iidA:
undetectable		 5dsgA-1iidA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iir GLYCOSYLTRANSFERASE
GTFB

(Amycolatopsis
orientalis) 		PF03033
(Glyco_transf_28) 		3 ASN A 159
LEU A 210
PHE A 188
 None
 0.82A 5dsgA-1iirA:
undetectable		 5dsgA-1iirA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ioo SF11-RNASE

(Nicotiana alata) 		PF00445
(Ribonuclease_T2) 		3 ASN A 173
LEU A  34
PHE A 178
 None
 0.80A 5dsgA-1iooA:
undetectable		 5dsgA-1iooA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ioo SF11-RNASE

(Nicotiana alata) 		PF00445
(Ribonuclease_T2) 		3 ASN A 173
LEU A 111
PHE A 178
 None
 0.76A 5dsgA-1iooA:
undetectable		 5dsgA-1iooA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkh MEVALONATE KINASE

(Methanocaldococcus
jannaschii) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		3 ASN A 270
LEU A 303
PHE A 274
 None
 0.68A 5dsgA-1kkhA:
undetectable		 5dsgA-1kkhA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1laj CAPSID PROTEIN

(Tomato aspermy
virus) 		PF00760
(Cucumo_coat) 		3 ASN A 112
LEU A 150
PHE A  58
 None
 0.81A 5dsgA-1lajA:
undetectable		 5dsgA-1lajA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9s INTERNALIN B

(Listeria
monocytogenes) 		PF08191
(LRR_adjacent)
PF09479
(Flg_new)
PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13457
(SH3_8) 		3 ASN A 130
LEU A 116
PHE A 126
 None
 0.70A 5dsgA-1m9sA:
undetectable		 5dsgA-1m9sA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mox EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		3 ASN A 128
LEU A  14
PHE A 126
 None
 0.81A 5dsgA-1moxA:
undetectable		 5dsgA-1moxA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n4o L2 BETA-LACTAMASE

(Stenotrophomonas
maltophilia) 		PF13354
(Beta-lactamase2) 		3 ASN A 245
LEU A 190
PHE A  72
 None
 0.78A 5dsgA-1n4oA:
undetectable		 5dsgA-1n4oA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nyt SHIKIMATE
5-DEHYDROGENASE

(Escherichia
coli) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		3 ASN A  86
LEU A  47
PHE A  69
 DTV  A1405 (-4.0A)
None
None
 0.81A 5dsgA-1nytA:
undetectable		 5dsgA-1nytA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5e SERINE PROTEASE
HEPSIN

(Homo sapiens) 		PF09272
(Hepsin-SRCR) 		3 ASN L  37
LEU L  86
PHE L 100
 None
 0.73A 5dsgA-1o5eL:
undetectable		 5dsgA-1o5eL:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o99 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Geobacillus
stearothermophilus) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 ASN A 398
LEU A 484
PHE A  14
 None
 0.65A 5dsgA-1o99A:
undetectable		 5dsgA-1o99A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p6s RAC-BETA
SERINE/THREONINE
PROTEIN KINASE

(Homo sapiens) 		PF00169
(PH) 		3 ASN A  53
LEU A  78
PHE A  88
 None
 0.74A 5dsgA-1p6sA:
undetectable		 5dsgA-1p6sA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pho PHOSPHOPORIN

(Escherichia
coli) 		PF00267
(Porin_1) 		3 ASN A 252
LEU A 324
PHE A 250
 None
 0.77A 5dsgA-1phoA:
undetectable		 5dsgA-1phoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE

(Leishmania
mexicana) 		PF00342
(PGI) 		3 ASN A 314
LEU A 338
PHE A 295
 None
 0.74A 5dsgA-1q50A:
undetectable		 5dsgA-1q50A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		3 ASN A 373
LEU A 428
PHE A 332
 None
 0.00A 5dsgA-1q5aA:
undetectable		 5dsgA-1q5aA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqj FUMARYLACETOACETATE
HYDROLASE

(Mus musculus) 		PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N) 		3 ASN A 318
LEU A 230
PHE A 295
 None
 0.80A 5dsgA-1qqjA:
undetectable		 5dsgA-1qqjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		3 ASN A 193
LEU A 224
PHE A 268
 None
 0.77A 5dsgA-1qvrA:
undetectable		 5dsgA-1qvrA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwj CYTIDINE
MONOPHOSPHO-N-ACETYL
NEURAMINIC ACID
SYNTHETASE

(Mus musculus) 		PF02348
(CTP_transf_3) 		3 ASN A 139
LEU A 152
PHE A 168
 None
 0.71A 5dsgA-1qwjA:
undetectable		 5dsgA-1qwjA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Escherichia
coli) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 ASN A 307
LEU A 295
PHE A 345
 None
 0.79A 5dsgA-1t4bA:
undetectable		 5dsgA-1t4bA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0n PLATELET
GLYCOPROTEIN IB

(Homo sapiens) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		3 ASN D 205
LEU D 220
PHE D 201
 None
 0.83A 5dsgA-1u0nD:
undetectable		 5dsgA-1u0nD:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ARP2/3 COMPLEX 34KDA
SUBUNIT

(Bos taurus) 		PF04045
(P34-Arc) 		3 ASN D 242
LEU D 227
PHE D 121
 None
 0.75A 5dsgA-1u2vD:
undetectable		 5dsgA-1u2vD:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		3 ASN A 186
LEU A 155
PHE A 181
 None
 0.75A 5dsgA-1v4gA:
undetectable		 5dsgA-1v4gA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc9 NDX1

(Thermus
thermophilus) 		PF00293
(NUDIX) 		3 ASN A  11
LEU A 121
PHE A  99
 None
 0.77A 5dsgA-1vc9A:
undetectable		 5dsgA-1vc9A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vgm 378AA LONG
HYPOTHETICAL CITRATE
SYNTHASE

(Sulfurisphaera
tokodaii) 		PF00285
(Citrate_synt) 		3 ASN A 134
LEU A 104
PHE A  74
 None
 0.73A 5dsgA-1vgmA:
2.4		 5dsgA-1vgmA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		3 ASN A 437
LEU A 443
PHE A 434
 None
 0.72A 5dsgA-1w27A:
2.7		 5dsgA-1w27A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xew SMC PROTEIN

(Pyrococcus
furiosus) 		PF02463
(SMC_N) 		3 ASN X  41
LEU Y1095
PHE X  48
 None
 0.78A 5dsgA-1xewX:
undetectable		 5dsgA-1xewX:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybi NON-TOXIN
HAEMAGGLUTININ HA34

(Clostridium
botulinum) 		PF05588
(Botulinum_HA-17)
PF14200
(RicinB_lectin_2) 		3 ASN A 104
LEU A  11
PHE A 140
 None
 0.73A 5dsgA-1ybiA:
undetectable		 5dsgA-1ybiA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yp0 NUCLEAR RECEPTOR
SUBFAMILY 5, GROUP
A, MEMBER 1

(Mus musculus) 		PF00104
(Hormone_recep) 		3 ASN A 451
LEU A 249
PHE A 274
 None
 0.77A 5dsgA-1yp0A:
undetectable		 5dsgA-1yp0A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvl SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind)
PF02865
(STAT_int) 		3 ASN A 520
LEU A 590
PHE A 581
 None
 0.73A 5dsgA-1yvlA:
3.6		 5dsgA-1yvlA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yy5 FMS1 PROTEIN

(Saccharomyces
cerevisiae) 		PF01593
(Amino_oxidase) 		3 ASN A 120
LEU A 171
PHE A 125
 None
 0.78A 5dsgA-1yy5A:
undetectable		 5dsgA-1yy5A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzp PEROXIDASE
MANGANESE-DEPENDENT
I

(Phanerochaete
chrysosporium) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		3 ASN A 260
LEU A 315
PHE A 202
 None
 0.80A 5dsgA-1yzpA:
undetectable		 5dsgA-1yzpA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zv6 EPB49 PROTEIN

(Homo sapiens) 		PF02209
(VHP)
PF16182
(AbLIM_anchor) 		3 ASN A  23
LEU A  42
PHE A  76
 None
 0.82A 5dsgA-1zv6A:
undetectable		 5dsgA-1zv6A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ad9 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1

(Homo sapiens) 		no annotation 3 ASN A 132
LEU A  89
PHE A 130
 C  B 149 ( 3.3A)
U  B 150 ( 4.2A)
None
 0.77A 5dsgA-2ad9A:
undetectable		 5dsgA-2ad9A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3o TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 6

(Homo sapiens) 		PF00017
(SH2)
PF00102
(Y_phosphatase) 		3 ASN A 101
LEU A  18
PHE A   5
 None
 0.77A 5dsgA-2b3oA:
undetectable		 5dsgA-2b3oA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		3 ASN C  97
LEU C  42
PHE C 217
 None
 0.81A 5dsgA-2bg9C:
undetectable		 5dsgA-2bg9C:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bkr SENTRIN-SPECIFIC
PROTEASE 8

(Homo sapiens) 		PF02902
(Peptidase_C48) 		3 ASN A  41
LEU A 205
PHE A  36
 None
 0.82A 5dsgA-2bkrA:
undetectable		 5dsgA-2bkrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bru NAD(P)
TRANSHYDROGENASE
SUBUNIT ALPHA

(Escherichia
coli) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		3 ASN A1098
LEU A1089
PHE A1092
 None
 0.80A 5dsgA-2bruA:
undetectable		 5dsgA-2bruA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ct8 METHIONYL-TRNA
SYNTHETASE

(Aquifex
aeolicus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		3 ASN A 236
LEU A 272
PHE A 263
 MSP  A 501 (-4.7A)
None
None
 0.82A 5dsgA-2ct8A:
undetectable		 5dsgA-2ct8A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE

(Streptococcus
gordonii) 		PF00728
(Glyco_hydro_20) 		3 ASN X 427
LEU X 475
PHE X 343
 None
 0.81A 5dsgA-2epkX:
3.5		 5dsgA-2epkX:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f31 DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ASN A 217
LEU A 260
PHE A 220
 None
 0.82A 5dsgA-2f31A:
undetectable		 5dsgA-2f31A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8a GLUTATHIONE
PEROXIDASE 1

(Homo sapiens) 		PF00255
(GSHPx) 		3 ASN A  87
LEU A  94
PHE A 110
 None
 0.78A 5dsgA-2f8aA:
undetectable		 5dsgA-2f8aA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fe8 REPLICASE
POLYPROTEIN 1AB

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		3 ASN A  14
LEU A  65
PHE A   9
 None
 0.80A 5dsgA-2fe8A:
undetectable		 5dsgA-2fe8A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g8s GLUCOSE/SORBOSONE
DEHYDROGENASES

(Escherichia
coli) 		PF07995
(GSDH) 		3 ASN A  26
LEU A 106
PHE A  22
 None
EDO  A3016 (-4.6A)
EDO  A3020 (-4.7A)
 0.75A 5dsgA-2g8sA:
undetectable		 5dsgA-2g8sA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ga8 HYPOTHETICAL 39.9
KDA PROTEIN

(Saccharomyces
cerevisiae) 		PF07728
(AAA_5) 		3 ASN A  49
LEU A  15
PHE A 259
 CME  A  45 ( 3.6A)
None
None
 0.72A 5dsgA-2ga8A:
undetectable		 5dsgA-2ga8A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gti REPLICASE
POLYPROTEIN 1AB

(Murine
coronavirus) 		PF06471
(NSP11) 		3 ASN A  45
LEU A   2
PHE A  58
 None
None
GOL  A 601 ( 4.3A)
 0.79A 5dsgA-2gtiA:
undetectable		 5dsgA-2gtiA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hdx SH2-B PH DOMAIN
CONTAINING SIGNALING
MEDIATOR 1 GAMMA
ISOFORM

(Mus musculus) 		PF00017
(SH2) 		3 ASN A 582
LEU A 522
PHE A 594
 None
 0.76A 5dsgA-2hdxA:
undetectable		 5dsgA-2hdxA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3y EPIDIDYMAL SECRETORY
GLUTATHIONE
PEROXIDASE

(Homo sapiens) 		PF00255
(GSHPx) 		3 ASN A 112
LEU A 119
PHE A 135
 None
 0.75A 5dsgA-2i3yA:
undetectable		 5dsgA-2i3yA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icw MYCOPLASMA
ARTHRITIDIS MITOGEN

(Mycoplasma
arthritidis) 		PF09245
(MA-Mit) 		3 ASN G  67
LEU G 118
PHE G  60
 None
 0.67A 5dsgA-2icwG:
undetectable		 5dsgA-2icwG:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ify 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Bacillus
anthracis) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 ASN A 397
LEU A 483
PHE A  13
 None
 0.65A 5dsgA-2ifyA:
undetectable		 5dsgA-2ifyA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuk SEED LIPOXYGENASE

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 ASN A 172
LEU A 184
PHE A 169
 None
 0.74A 5dsgA-2iukA:
undetectable		 5dsgA-2iukA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lc4 PILP PROTEIN

(Pseudomonas
aeruginosa) 		PF04351
(PilP) 		3 ASN A  65
LEU A  97
PHE A  26
 None
 0.71A 5dsgA-2lc4A:
undetectable		 5dsgA-2lc4A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lxi RNA-BINDING PROTEIN
10

(Homo sapiens) 		PF00076
(RRM_1) 		3 ASN A   2
LEU A  22
PHE A  48
 None
 0.75A 5dsgA-2lxiA:
undetectable		 5dsgA-2lxiA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oh1 ACETYLTRANSFERASE,
GNAT FAMILY

(Listeria
monocytogenes) 		no annotation 3 ASN A  27
LEU A  68
PHE A  52
 None
 0.71A 5dsgA-2oh1A:
undetectable		 5dsgA-2oh1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p65 HYPOTHETICAL PROTEIN
PF08_0063

(Plasmodium
falciparum) 		PF00004
(AAA) 		3 ASN A  45
LEU A  76
PHE A 120
 None
 0.64A 5dsgA-2p65A:
undetectable		 5dsgA-2p65A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2quq CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
B

(Saccharomyces
cerevisiae) 		PF16846
(Cep3) 		3 ASN A 211
LEU A 240
PHE A 218
 None
 0.65A 5dsgA-2quqA:
undetectable		 5dsgA-2quqA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r37 GLUTATHIONE
PEROXIDASE 3

(Homo sapiens) 		PF00255
(GSHPx) 		3 ASN A 112
LEU A 119
PHE A 135
 None
 0.76A 5dsgA-2r37A:
undetectable		 5dsgA-2r37A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rkq PEPTIDOGLYCAN-RECOGN
ITION PROTEIN-SD

(Drosophila
melanogaster) 		PF01510
(Amidase_2) 		3 ASN A 114
LEU A  61
PHE A 111
 None
 0.81A 5dsgA-2rkqA:
undetectable		 5dsgA-2rkqA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1u CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG

(Aeropyrum
pernix) 		PF09079
(Cdc6_C)
PF13191
(AAA_16) 		3 ASN A 194
LEU A  60
PHE A 153
 None
 0.81A 5dsgA-2v1uA:
undetectable		 5dsgA-2v1uA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5n CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00878
(CIMR) 		3 ASN A1743
LEU A1663
PHE A1787
 None
 0.68A 5dsgA-2v5nA:
undetectable		 5dsgA-2v5nA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4k DEATH-ASSOCIATED
PROTEIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		3 ASN A 144
LEU A  68
PHE A 138
 MG  A1304 ( 4.2A)
None
None
 0.77A 5dsgA-2w4kA:
undetectable		 5dsgA-2w4kA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyh ALPHA-MANNOSIDASE

(Streptococcus
pyogenes) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		3 ASN A 317
LEU A 338
PHE A 837
 None
GOL  A 904 (-4.7A)
None
 0.82A 5dsgA-2wyhA:
1.9		 5dsgA-2wyhA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3k ACSD

(Dickeya
chrysanthemi) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		3 ASN A  24
LEU A  37
PHE A  84
 None
 0.75A 5dsgA-2x3kA:
undetectable		 5dsgA-2x3kA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf2 CATALASE

(Penicillium
janthinellum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 ASN A 484
LEU A 190
PHE A 509
 None
 0.74A 5dsgA-2xf2A:
undetectable		 5dsgA-2xf2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfg ENDOGLUCANASE 1

(Ruminiclostridium
thermocellum) 		PF00942
(CBM_3) 		3 ASN B 540
LEU B 519
PHE B 503
 None
 0.74A 5dsgA-2xfgB:
undetectable		 5dsgA-2xfgB:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5q INTERNALIN B

(Listeria
monocytogenes) 		PF08191
(LRR_adjacent)
PF12354
(Internalin_N)
PF12799
(LRR_4) 		3 ASN A 108
LEU A 116
PHE A 104
 None
 0.81A 5dsgA-2y5qA:
undetectable		 5dsgA-2y5qA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yab DEATH-ASSOCIATED
PROTEIN KINASE 2

(Mus musculus) 		PF00069
(Pkinase) 		3 ASN A 144
LEU A  68
PHE A 138
 AMP  A1302 ( 4.8A)
None
None
 0.78A 5dsgA-2yabA:
undetectable		 5dsgA-2yabA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agr NUCLEOSIDE
TRIPHOSPHATE
HYDROLASE

(Neospora
caninum) 		PF01150
(GDA1_CD39) 		3 ASN A 279
LEU A 248
PHE A 285
 None
 0.76A 5dsgA-3agrA:
undetectable		 5dsgA-3agrA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asa LL-DIAMINOPIMELATE
AMINOTRANSFERASE

(Chlamydia
trachomatis) 		PF00155
(Aminotran_1_2) 		3 ASN A 181
LEU A 169
PHE A 154
 None
 0.78A 5dsgA-3asaA:
undetectable		 5dsgA-3asaA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ax1 SERRATE RNA EFFECTOR
MOLECULE

(Arabidopsis
thaliana) 		PF04959
(ARS2)
PF12066
(DUF3546) 		3 ASN A 289
LEU A 262
PHE A 270
 None
 0.81A 5dsgA-3ax1A:
undetectable		 5dsgA-3ax1A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 ASN A 671
LEU A 704
PHE A 737
 None
 0.77A 5dsgA-3bgaA:
undetectable		 5dsgA-3bgaA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3j PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Escherichia
coli) 		PF01380
(SIS) 		3 ASN A 155
LEU A  54
PHE A 157
 None
 0.75A 5dsgA-3c3jA:
1.2		 5dsgA-3c3jA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE EPSILON SUBUNIT

(Methanosarcina
barkeri) 		PF02552
(CO_dh) 		3 ASN G  86
LEU G 102
PHE G  92
 None
 0.69A 5dsgA-3cf4G:
undetectable		 5dsgA-3cf4G:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cih PUTATIVE
ALPHA-RHAMNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		3 ASN A 127
LEU A 106
PHE A  74
 None
 0.82A 5dsgA-3cihA:
undetectable		 5dsgA-3cihA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dw8 SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
55 KDA REGULATORY
SUBUNIT B ALPHA
ISOFORM

(Homo sapiens) 		no annotation 3 ASN B 237
LEU B 313
PHE B 234
 None
 0.77A 5dsgA-3dw8B:
undetectable		 5dsgA-3dw8B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewd ADENOSINE DEAMINASE

(Plasmodium
vivax) 		PF00962
(A_deaminase) 		3 ASN A 340
LEU A  16
PHE A 331
 None
 0.82A 5dsgA-3ewdA:
undetectable		 5dsgA-3ewdA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 ASN B 831
LEU B1076
PHE B 990
 None
 0.80A 5dsgA-3h0gB:
undetectable		 5dsgA-3h0gB:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjb GLUCOSE-6-PHOSPHATE
ISOMERASE

(Vibrio cholerae) 		PF00342
(PGI) 		3 ASN A 260
LEU A 284
PHE A 241
 None
 0.82A 5dsgA-3hjbA:
undetectable		 5dsgA-3hjbA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0w 8-OXOGUANINE-DNA-GLY
COSYLASE

(Clostridium
acetobutylicum) 		PF00730
(HhH-GPD)
PF07934
(OGG_N) 		3 ASN A 288
LEU A 251
PHE A 282
 None
 0.66A 5dsgA-3i0wA:
undetectable		 5dsgA-3i0wA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic9 DIHYDROLIPOAMIDE
DEHYDROGENASE

(Colwellia
psychrerythraea) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 ASN A 312
LEU A 276
PHE A 306
 NA  A 491 (-2.6A)
None
None
 0.71A 5dsgA-3ic9A:
undetectable		 5dsgA-3ic9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic9 DIHYDROLIPOAMIDE
DEHYDROGENASE

(Colwellia
psychrerythraea) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 ASN A 312
LEU A 278
PHE A 306
 NA  A 491 (-2.6A)
None
None
 0.78A 5dsgA-3ic9A:
undetectable		 5dsgA-3ic9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Bacteroides
fragilis) 		no annotation 3 ASN A 527
LEU A 558
PHE A 567
 None
 0.64A 5dsgA-3ig2A:
undetectable		 5dsgA-3ig2A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3irz URO-ADHERENCE FACTOR
A

(Staphylococcus
saprophyticus) 		PF17210
(SdrD_B) 		3 ASN A 799
LEU A 726
PHE A 695
 None
 0.74A 5dsgA-3irzA:
undetectable		 5dsgA-3irzA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ka7 OXIDOREDUCTASE

(Methanosarcina
mazei) 		PF01593
(Amino_oxidase) 		3 ASN A 181
LEU A 163
PHE A 176
 None
 0.77A 5dsgA-3ka7A:
undetectable		 5dsgA-3ka7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Coxiella
burnetii) 		PF07515
(TraI_2_C) 		3 ASN A 272
LEU A 264
PHE A 286
 None
 0.79A 5dsgA-3kq5A:
2.3		 5dsgA-3kq5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4k DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		3 ASN A 540
LEU A 630
PHE A 546
 None
 0.78A 5dsgA-3l4kA:
undetectable		 5dsgA-3l4kA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lu2 LMO2462 PROTEIN

(Listeria
monocytogenes) 		PF01244
(Peptidase_M19) 		3 ASN A 162
LEU A 117
PHE A 167
 None
 0.76A 5dsgA-3lu2A:
undetectable		 5dsgA-3lu2A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lyn SPERM LYSIN

(Haliotis
fulgens) 		PF01303
(Egg_lysin) 		3 ASN A  45
LEU A  35
PHE A  52
 None
 0.76A 5dsgA-3lynA:
undetectable		 5dsgA-3lynA:
15.29