SIMILAR PATTERNS OF AMINO ACIDS FOR 5DQY_A_BEZA401_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c9w CHO REDUCTASE

(Cricetulus
griseus) 		PF00248
(Aldo_ket_red) 		4 ILE A 109
PHE A 137
VAL A 158
GLU A 308
 None
 1.15A 5dqyA-1c9wA:
0.0		 5dqyA-1c9wA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqj SUCCINYL-COA
SYNTHETASE ALPHA
CHAIN

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		4 ILE A  95
GLN A  13
SER A  80
CYH A  77
 COA  A 901 (-4.8A)
None
COA  A 901 (-4.2A)
None
 1.16A 5dqyA-1cqjA:
0.0		 5dqyA-1cqjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dqu ISOCITRATE LYASE

(Aspergillus
nidulans) 		PF00463
(ICL) 		4 ILE A 316
LYS A 325
VAL A 313
GLU A 329
 None
 0.98A 5dqyA-1dquA:
0.0		 5dqyA-1dquA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e43 ALPHA-AMYLASE

(Bacillus
amyloliquefaciens) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 ILE A 377
GLN A 293
SER A 337
GLU A 336
 None
 1.09A 5dqyA-1e43A:
0.0		 5dqyA-1e43A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eaz TANDEM PH DOMAIN
CONTAINING PROTEIN-1

(Homo sapiens) 		PF00169
(PH) 		4 ILE A 288
LYS A 242
VAL A 284
GLN A 244
 None
 1.13A 5dqyA-1eazA:
0.0		 5dqyA-1eazA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee6 PECTATE LYASE

(Bacillus sp.
KSM-P15) 		PF03211
(Pectate_lyase) 		4 ILE A 117
PHE A 109
VAL A  94
GLN A 110
 None
 1.02A 5dqyA-1ee6A:
0.0		 5dqyA-1ee6A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fq3 GRANZYME B

(Homo sapiens) 		PF00089
(Trypsin) 		4 LYS A  86
VAL A  66
GLN A 107
GLU A 109
 None
 1.04A 5dqyA-1fq3A:
0.0		 5dqyA-1fq3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION

(Escherichia
coli) 		PF00293
(NUDIX) 		4 ILE A 185
VAL A 191
GLN A 198
GLU A 181
 None
 1.17A 5dqyA-1ga7A:
undetectable		 5dqyA-1ga7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz4 NAD-DEPENDENT MALIC
ENZYME

(Homo sapiens) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ILE A 404
PHE A 399
VAL A 403
GLU A 427
 None
 0.86A 5dqyA-1gz4A:
2.1		 5dqyA-1gz4A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5t INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE

(Thermotoga
maritima) 		PF00218
(IGPS) 		4 ILE A 212
PHE A 221
VAL A 208
GLU A 224
 None
 1.01A 5dqyA-1j5tA:
undetectable		 5dqyA-1j5tA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE

(Sulfolobus
solfataricus) 		PF01048
(PNP_UDP_1) 		4 ILE A 103
VAL A 105
SER A 156
CYH A 183
 None
 1.17A 5dqyA-1jdzA:
undetectable		 5dqyA-1jdzA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m46 MYOSIN LIGHT CHAIN
IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7)
no annotation 		4 ILE A 143
PHE A  86
VAL A 146
GLN B 863
 None
 0.99A 5dqyA-1m46A:
undetectable		 5dqyA-1m46A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1of9 PORE-FORMING PEPTIDE
AMEOBAPORE A

(Entamoeba
histolytica) 		PF03489
(SapB_2) 		4 ILE A  70
LYS A  56
VAL A  65
GLN A  59
 None
 1.01A 5dqyA-1of9A:
undetectable		 5dqyA-1of9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1py5 TGF-BETA RECEPTOR
TYPE I

(Homo sapiens) 		PF00069
(Pkinase)
PF08515
(TGF_beta_GS) 		4 ILE A 303
VAL A 299
GLU A 462
CYH A 461
 None
 1.15A 5dqyA-1py5A:
undetectable		 5dqyA-1py5A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1toa PROTEIN (PERIPLASMIC
BINDING PROTEIN
TROA)

(Treponema
pallidum) 		PF01297
(ZnuA) 		4 ILE A  50
PHE A 163
GLN A 165
GLU A 162
 None
 1.14A 5dqyA-1toaA:
undetectable		 5dqyA-1toaA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uem KIAA1568 PROTEIN

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A  51
PHE A  87
VAL A  65
SER A  55
 None
 1.18A 5dqyA-1uemA:
undetectable		 5dqyA-1uemA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wrb DJVLGB

(Dugesia
japonica) 		PF00270
(DEAD) 		4 ILE A 266
VAL A 316
GLN A 276
GLU A 280
 None
 0.91A 5dqyA-1wrbA:
undetectable		 5dqyA-1wrbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy2 XAA-PRO DIPEPTIDASE

(Pyrococcus
horikoshii) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 ILE A 313
VAL A 299
GLN A 248
GLU A 330
 None
None
None
ZN  A 405 (-2.3A)
 1.11A 5dqyA-1wy2A:
undetectable		 5dqyA-1wy2A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtj PROBABLE
ATP-DEPENDENT RNA
HELICASE P47

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 ILE A 194
SER A 228
GLU A 197
CYH A 198
 None
None
MG  A 501 (-4.0A)
None
 1.17A 5dqyA-1xtjA:
undetectable		 5dqyA-1xtjA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yhn RAS-RELATED PROTEIN
RAB-7

(Homo sapiens) 		PF00071
(Ras) 		4 ILE A 149
PHE A 120
GLN A 176
CYH A  83
 None
 0.98A 5dqyA-1yhnA:
undetectable		 5dqyA-1yhnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17

(Homo sapiens) 		PF00615
(RGS) 		4 ILE X 159
VAL X 155
GLN X 175
GLU X 172
 None
 0.98A 5dqyA-1zv4X:
undetectable		 5dqyA-1zv4X:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		4 ILE A  26
VAL A  38
GLN A 108
GLU A  53
 None
None
None
DCZ  A 302 (-3.0A)
 1.06A 5dqyA-2a30A:
undetectable		 5dqyA-2a30A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5l TRP REPRESSOR
BINDING PROTEIN WRBA

(Pseudomonas
aeruginosa) 		PF03358
(FMN_red) 		4 ILE A   6
LYS A 187
GLN A  30
GLU A 191
 None
 1.09A 5dqyA-2a5lA:
undetectable		 5dqyA-2a5lA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0o DIOL
DEHYDRATASE-REACTIVA
TING FACTOR LARGE
SUBUNIT

(Klebsiella
oxytoca) 		PF08841
(DDR) 		4 LYS A 380
VAL A 385
GLN A  51
GLU A 376
 None
 0.89A 5dqyA-2d0oA:
undetectable		 5dqyA-2d0oA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fjl 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
GAMMA 1

(Rattus
norvegicus) 		PF00169
(PH) 		4 ILE A 143
VAL A  95
GLN A 148
GLU A 145
 None
 0.91A 5dqyA-2fjlA:
undetectable		 5dqyA-2fjlA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjr MALATE DEHYDROGENASE

(Cryptosporidium
parvum) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 192
LYS A 306
PHE A 309
VAL A 184
 None
 1.08A 5dqyA-2hjrA:
undetectable		 5dqyA-2hjrA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hne L-FUCONATE
DEHYDRATASE

(Xanthomonas
campestris) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 270
VAL A 295
GLN A 264
GLU A 267
 None
 1.07A 5dqyA-2hneA:
undetectable		 5dqyA-2hneA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i8l HYDROGENASE 3
MATURATION PROTEASE

(Escherichia
coli) 		PF01750
(HycI) 		4 ILE A 105
VAL A 108
GLN A 100
GLU A 103
 None
 1.13A 5dqyA-2i8lA:
undetectable		 5dqyA-2i8lA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jmz HYPOTHETICAL PROTEIN
MJ0781

(Methanocaldococcus
jannaschii) 		PF14890
(Intein_splicing) 		4 ILE A  50
PHE A  32
VAL A  77
GLU A  55
 None
 1.08A 5dqyA-2jmzA:
undetectable		 5dqyA-2jmzA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lci PROTEIN OR36

(synthetic
construct) 		no annotation 4 ILE A   5
PHE A 120
GLN A 122
GLU A 119
 None
 1.00A 5dqyA-2lciA:
2.0		 5dqyA-2lciA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozf EZRIN-RADIXIN-MOESIN
-BINDING
PHOSPHOPROTEIN 50

(Homo sapiens) 		PF00595
(PDZ) 		4 ILE A 199
VAL A 230
SER A 191
CYH A 155
 None
 1.14A 5dqyA-2ozfA:
undetectable		 5dqyA-2ozfA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE

(Bacillus
subtilis) 		PF01634
(HisG) 		4 ILE A 135
PHE A 126
GLN A 132
GLU A 131
 None
 0.99A 5dqyA-2vd2A:
undetectable		 5dqyA-2vd2A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w55 XANTHINE
DEHYDROGENASE

(Rhodobacter
capsulatus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 ILE B 722
PHE B 723
GLN B 498
SER B   2
 None
 1.16A 5dqyA-2w55B:
undetectable		 5dqyA-2w55B:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF09040
(H-K_ATPase_N)
PF13246
(Cation_ATPase) 		4 ILE A 993
VAL A 930
GLN A 884
GLU A 885
 None
 1.15A 5dqyA-2yn9A:
undetectable		 5dqyA-2yn9A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zab ALGINATE LYASE

(Sphingomonas
sp. A1) 		PF08787
(Alginate_lyase2) 		4 ILE A 245
LYS A 205
VAL A 254
GLN A 216
 None
 0.92A 5dqyA-2zabA:
undetectable		 5dqyA-2zabA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3atg GLUCANASE

(Cellulosimicrobium
cellulans) 		PF00722
(Glyco_hydro_16) 		4 ILE A  58
LYS A 231
VAL A 210
GLN A  91
 None
 1.14A 5dqyA-3atgA:
undetectable		 5dqyA-3atgA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b57 LIN1889 PROTEIN

(Listeria
innocua) 		PF01966
(HD) 		4 ILE A 118
LYS A  38
VAL A 119
GLU A  52
 None
 1.00A 5dqyA-3b57A:
undetectable		 5dqyA-3b57A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bsx PUMILIO HOMOLOG 1

(Homo sapiens) 		PF00806
(PUF) 		4 ILE A 866
PHE A 856
GLN A 858
GLU A 855
 None
 1.02A 5dqyA-3bsxA:
undetectable		 5dqyA-3bsxA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cc1 PUTATIVE
ALPHA-N-ACETYLGALACT
OSAMINIDASE

(Bacillus
halodurans) 		PF16499
(Melibiase_2) 		4 ILE A  49
LYS A 108
VAL A  50
GLU A  47
 None
 1.18A 5dqyA-3cc1A:
undetectable		 5dqyA-3cc1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f8r THIOREDOXIN
REDUCTASE (TRXB-3)

(Sulfolobus
solfataricus) 		PF07992
(Pyr_redox_2) 		4 LYS A 217
VAL A 243
GLN A 224
GLU A 215
 None
 1.05A 5dqyA-3f8rA:
undetectable		 5dqyA-3f8rA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h92 UNCHARACTERIZED
ATP-BINDING PROTEIN
MJECL15

(Methanocaldococcus
jannaschii) 		no annotation 4 ILE A  58
PHE A  61
VAL A  36
GLU A  65
 None
 1.10A 5dqyA-3h92A:
undetectable		 5dqyA-3h92A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hsk ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Candida
albicans) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 LYS A   2
PHE A  29
VAL A  80
GLU A  28
 None
 1.03A 5dqyA-3hskA:
undetectable		 5dqyA-3hskA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4r CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-ALPHA REGULATORY
SUBUNIT

(Mus musculus) 		PF00027
(cNMP_binding)
PF02197
(RIIa) 		4 VAL B 176
GLN B 129
GLU B 130
CYH B 132
 None
 0.91A 5dqyA-3j4rB:
undetectable		 5dqyA-3j4rB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k49 MRNA-BINDING PROTEIN
PUF3

(Saccharomyces
cerevisiae) 		PF00806
(PUF) 		4 LYS A 780
VAL A 761
GLN A 737
GLU A 779
 None
None
U  B   5 ( 2.7A)
G  B   4 ( 3.2A)
 1.12A 5dqyA-3k49A:
undetectable		 5dqyA-3k49A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8z NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 319
VAL A 321
GLU A 209
CYH A 206
 None
 1.16A 5dqyA-3k8zA:
undetectable		 5dqyA-3k8zA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3meb ASPARTATE
AMINOTRANSFERASE

(Giardia
intestinalis) 		PF00155
(Aminotran_1_2) 		4 ILE A 315
PHE A 325
VAL A 316
GLN A 323
 None
 1.19A 5dqyA-3mebA:
undetectable		 5dqyA-3mebA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mqw PUTATIVE
ENDORIBONUCLEASE
L-PSP

(Entamoeba
histolytica) 		PF01042
(Ribonuc_L-PSP) 		4 ILE A  24
VAL A  29
GLN A  21
GLU A  66
 None
 1.08A 5dqyA-3mqwA:
undetectable		 5dqyA-3mqwA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3r ALDO-KETO REDUCTASE
FAMILY 1, MEMBER B7

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		4 ILE A  59
VAL A  55
SER A  77
CYH A  45
 None
 0.96A 5dqyA-3o3rA:
0.8		 5dqyA-3o3rA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o9t NONSTRUCTURAL
PROTEIN 1

(Influenza A
virus) 		PF00600
(Flu_NS1) 		4 ILE A 182
VAL A 178
GLN A 199
SER A 195
 None
 1.00A 5dqyA-3o9tA:
undetectable		 5dqyA-3o9tA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ops MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Paenibacillus
sp. Y412MC10) 		PF13378
(MR_MLE_C) 		4 ILE A 194
PHE A 167
VAL A 197
GLN A 158
 None
 1.16A 5dqyA-3opsA:
undetectable		 5dqyA-3opsA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pkz RECOMBINASE SIN

(Staphylococcus
aureus) 		PF00239
(Resolvase) 		4 ILE A   3
PHE A  59
VAL A  53
GLN A  87
 None
 1.07A 5dqyA-3pkzA:
undetectable		 5dqyA-3pkzA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps5 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 6

(Homo sapiens) 		PF00017
(SH2)
PF00102
(Y_phosphatase) 		4 ILE A 449
VAL A 346
SER A 442
GLU A 441
 None
 1.08A 5dqyA-3ps5A:
undetectable		 5dqyA-3ps5A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qlt GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 2

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 LYS A  63
VAL A  87
GLN A  50
GLU A  59
 None
 0.82A 5dqyA-3qltA:
2.6		 5dqyA-3qltA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus) 		PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C) 		4 ILE A 112
VAL A 142
GLN A 116
SER A 119
 None
 1.19A 5dqyA-3t05A:
undetectable		 5dqyA-3t05A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vgl GLUCOKINASE

(Streptomyces
griseus) 		PF00480
(ROK) 		4 ILE A 139
VAL A 125
GLN A 120
GLU A 113
 None
 1.08A 5dqyA-3vglA:
undetectable		 5dqyA-3vglA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 ILE A 819
LYS A 828
VAL A 815
GLU A 832
 None
 1.20A 5dqyA-3x1lA:
undetectable		 5dqyA-3x1lA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE

(Parageobacillus
thermoglucosidasius) 		PF00465
(Fe-ADH) 		4 ILE A 819
VAL A 824
SER A 831
GLU A 830
 None
 1.07A 5dqyA-3zdrA:
undetectable		 5dqyA-3zdrA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4are COLLAGENASE G

(Hathewaya
histolytica) 		PF01752
(Peptidase_M9)
PF08453
(Peptidase_M9_N) 		4 ILE A 315
PHE A 349
VAL A 259
GLU A 294
 None
 1.12A 5dqyA-4areA:
undetectable		 5dqyA-4areA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4axz PUTATIVE ANTIGEN P35

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		4 ILE A  99
PHE A 102
VAL A 197
GLN A 104
 None
 1.10A 5dqyA-4axzA:
undetectable		 5dqyA-4axzA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 ILE A 262
VAL A   7
GLN A 104
CYH A 107
 None
 0.82A 5dqyA-4c2kA:
undetectable		 5dqyA-4c2kA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 ILE A 262
VAL A   7
GLN A 104
GLU A 105
 None
 1.03A 5dqyA-4c2kA:
undetectable		 5dqyA-4c2kA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dks PROBABLE INTEGRASE

(Sulfolobus
spindle-shaped
virus 1) 		PF16795
(Phage_integr_3) 		4 ILE A 297
LYS A 322
VAL A 293
GLU A 323
 None
 1.16A 5dqyA-4dksA:
undetectable		 5dqyA-4dksA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e72 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF11738
(DUF3298) 		4 ILE A 238
PHE A 167
VAL A 239
GLN A 156
 None
 0.97A 5dqyA-4e72A:
undetectable		 5dqyA-4e72A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fe4 XYLOSE OPERON
REGULATORY PROTEIN

(Escherichia
coli) 		PF12833
(HTH_18)
PF13377
(Peripla_BP_3) 		4 ILE A 188
PHE A 124
VAL A 107
GLU A 140
 None
 1.00A 5dqyA-4fe4A:
2.3		 5dqyA-4fe4A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ggj MITOCHONDRIAL
CARDIOLIPIN
HYDROLASE

(Mus musculus) 		PF13091
(PLDc_2) 		4 ILE A 141
VAL A 143
GLN A 132
SER A 131
 None
 0.93A 5dqyA-4ggjA:
undetectable		 5dqyA-4ggjA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3f PROBABLE
TONB-DEPENDENT
RECEPTOR

(Pseudomonas
aeruginosa) 		PF03180
(Lipoprotein_9) 		4 ILE A  37
PHE A 247
GLN A 249
GLU A 250
 None
 1.04A 5dqyA-4k3fA:
undetectable		 5dqyA-4k3fA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnf GLUTAMINE SYNTHETASE

(Bacillus
subtilis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ILE A  21
PHE A  92
GLN A  24
CYH A  94
 None
 1.03A 5dqyA-4lnfA:
undetectable		 5dqyA-4lnfA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8u OLIGO-1,6-GLUCOSIDAS
E 1

(Bacillus
subtilis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 ILE A 204
PHE A 236
GLN A 238
GLU A 235
 None
 1.10A 5dqyA-4m8uA:
undetectable		 5dqyA-4m8uA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4miv N-SULPHOGLUCOSAMINE
SULPHOHYDROLASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 ILE A 121
LYS A 156
VAL A 175
GLU A 256
 None
 0.99A 5dqyA-4mivA:
undetectable		 5dqyA-4mivA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mni TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Polaromonas sp.
JS666) 		PF03480
(DctP) 		4 ILE A  65
VAL A  55
GLN A 249
GLU A  29
 None
 1.18A 5dqyA-4mniA:
1.3		 5dqyA-4mniA:
14.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4pom THIOREDOXIN

(Homo sapiens) 		PF00085
(Thioredoxin) 		4 ILE A   5
LYS A   8
PHE A  11
VAL A  57
 None
COM  A 200 ( 4.1A)
None
None
 0.42A 5dqyA-4pomA:
21.0		 5dqyA-4pomA:
96.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qme AMINOPEPTIDASE N

(Neisseria
meningitidis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 LYS A 100
PHE A 815
VAL A 819
GLU A 775
 None
 1.13A 5dqyA-4qmeA:
undetectable		 5dqyA-4qmeA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmg STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00565
(SNase) 		4 ILE A  24
VAL A  35
GLN A  38
GLU A  94
 None
 1.19A 5dqyA-4qmgA:
undetectable		 5dqyA-4qmgA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmc OLD YELLOW ENZYME

(Kluyveromyces
marxianus) 		PF00724
(Oxidored_FMN) 		4 ILE A  68
VAL A 111
GLN A 114
GLU A  71
 None
None
FMN  A 501 (-3.0A)
None
 0.81A 5dqyA-4tmcA:
undetectable		 5dqyA-4tmcA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xru RNL

(Capnocytophaga
gingivalis) 		PF16542
(PNKP_ligase) 		4 ILE B 126
SER B 119
GLU B 120
CYH B  67
 None
None
ATP  B 501 ( 2.9A)
None
 0.94A 5dqyA-4xruB:
undetectable		 5dqyA-4xruB:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zr5 NEPRILYSIN

(Oryctolagus
cuniculus) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		4 ILE A 336
LYS A 525
VAL A 334
GLN A 522
 None
 1.13A 5dqyA-4zr5A:
undetectable		 5dqyA-4zr5A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b22 NECTIN-3

(Mus musculus) 		PF07686
(V-set)
PF08205
(C2-set_2) 		4 ILE A  22
LYS A  91
VAL A  24
GLN A 101
 None
 0.74A 5dqyA-5b22A:
undetectable		 5dqyA-5b22A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1t SMALL GTPASE EHRABX3

(Entamoeba
histolytica) 		PF00071
(Ras) 		4 ILE A 124
PHE A 153
GLN A 144
GLU A 143
 None
 1.17A 5dqyA-5c1tA:
undetectable		 5dqyA-5c1tA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cd6 TPR-DOMAIN
CONTAINING PROTEIN

(Parabacteroides
distasonis) 		PF17128
(DUF5107) 		4 ILE A 277
VAL A 353
SER A 281
GLU A 280
 None
 0.93A 5dqyA-5cd6A:
undetectable		 5dqyA-5cd6A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fd2 SERINE/THREONINE-PRO
TEIN KINASE B-RAF

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LYS A 499
PHE A 498
VAL A 600
GLN A 496
 None
 1.13A 5dqyA-5fd2A:
undetectable		 5dqyA-5fd2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvh ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[FMN]

(Thermotoga
maritima) 		PF03060
(NMO) 		4 ILE A  43
VAL A  70
GLU A  89
CYH A  86
 None
 0.86A 5dqyA-5gvhA:
undetectable		 5dqyA-5gvhA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9f CRISPR SYSTEM
CASCADE SUBUNIT CASA

(Escherichia
coli) 		PF09481
(CRISPR_Cse1) 		4 ILE A 310
VAL A 314
SER A 427
GLU A 428
 None
 1.14A 5dqyA-5h9fA:
undetectable		 5dqyA-5h9fA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hca CALRETICULIN,CALRETI
CULIN

(Entamoeba
histolytica) 		no annotation 4 ILE C  95
VAL C 130
GLU C 157
CYH C 156
 None
 1.18A 5dqyA-5hcaC:
undetectable		 5dqyA-5hcaC:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxb EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
GTP-BINDING SUBUNIT
ERF3A
PROTEIN CEREBLON

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		4 ILE X 626
PHE Z 150
GLN Z 148
GLU Z 147
 85C  Z 502 (-3.9A)
None
None
None
 1.01A 5dqyA-5hxbX:
undetectable		 5dqyA-5hxbX:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i98 FK506-BINDING
PROTEIN 1

(Candida
albicans) 		PF00254
(FKBP_C) 		4 ILE A  81
LYS A  86
GLN A  12
GLU A 117
 None
 1.10A 5dqyA-5i98A:
undetectable		 5dqyA-5i98A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jd4 LAE6

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		4 ILE A  84
PHE A 138
VAL A 157
CYH A 171
 None
 0.97A 5dqyA-5jd4A:
1.4		 5dqyA-5jd4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5

(Saccharomyces
cerevisiae;
Homo sapiens) 		PF00227
(Proteasome) 		4 ILE K  13
LYS K   7
VAL K  14
CYH K 102
 None
 1.07A 5dqyA-5l5wK:
undetectable		 5dqyA-5l5wK:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqs BETA-L-ARABINOBIOSID
ASE

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2) 		4 ILE A 568
LYS A 465
VAL A 569
GLU A 566
 None
 1.19A 5dqyA-5mqsA:
undetectable		 5dqyA-5mqsA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n29 CTP SYNTHASE

(Trypanosoma
brucei) 		PF00117
(GATase) 		4 ILE A 492
VAL A 493
GLN A 583
CYH A 581
 None
 1.19A 5dqyA-5n29A:
0.6		 5dqyA-5n29A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofn DNA PRIMASE LARGE
SUBUNIT PRIL,PRIL-X
FUSION PROTEIN

(Sulfolobus
solfataricus) 		no annotation 4 ILE B 117
PHE B 138
GLU B 137
CYH B 120
 None
 1.19A 5dqyA-5ofnB:
undetectable		 5dqyA-5ofnB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t0g PROTEASOME SUBUNIT
BETA TYPE-5

(Homo sapiens) 		PF00227
(Proteasome) 		4 ILE R  13
LYS R   7
VAL R  14
CYH R 102
 None
 1.07A 5dqyA-5t0gR:
undetectable		 5dqyA-5t0gR:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uzu UNCHARACTERISED
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ILE B  88
LYS B  90
VAL B  98
GLN B  93
 None
 0.97A 5dqyA-5uzuB:
undetectable		 5dqyA-5uzuB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr PROTEASOME SUBUNIT
BETA TYPE-5

(Homo sapiens) 		no annotation 4 ILE R  13
LYS R   7
VAL R  14
CYH R 102
 None
 0.95A 5dqyA-5vfrR:
undetectable		 5dqyA-5vfrR:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wk1 CAPSID STABILIZING
PROTEIN

(Pseudoalteromonas
phage TW1) 		no annotation 4 LYS X 104
VAL X 108
GLU X 131
CYH X 145
 None
 0.98A 5dqyA-5wk1X:
undetectable		 5dqyA-5wk1X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE

(Trichomonas
vaginalis) 		PF00833
(Ribosomal_S17e) 		4 ILE R  17
VAL R  54
GLN R  23
CYH R  35
 None
 1.19A 5dqyA-5xyiR:
undetectable		 5dqyA-5xyiR:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ybw ASPARTATE RACEMASE

(Scapharca
broughtonii) 		no annotation 4 LYS A 119
PHE A 120
VAL A 130
GLN A  94
 None
 0.92A 5dqyA-5ybwA:
undetectable		 5dqyA-5ybwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykh PUMILIO HOMOLOG 1

(Homo sapiens) 		no annotation 4 ILE A  39
PHE A  29
GLN A  31
GLU A  28
 None
 0.88A 5dqyA-5ykhA:
undetectable		 5dqyA-5ykhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR

(Staphylococcus
aureus) 		no annotation 4 ILE B  88
LYS B  90
VAL B  98
GLN B  93
 None
 0.89A 5dqyA-6azpB:
undetectable		 5dqyA-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dgi D-ALANINE--D-ALANINE
LIGASE

(Vibrio cholerae) 		no annotation 4 ILE A 158
LYS A 149
PHE A 152
GLU A 177
 None
 1.11A 5dqyA-6dgiA:
1.6		 5dqyA-6dgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dgk -

(-) 		no annotation 4 ILE A 182
VAL A 178
GLN A 199
SER A 195
 None
 0.89A 5dqyA-6dgkA:
undetectable		 5dqyA-6dgkA:
undetectable