SIMILAR PATTERNS OF AMINO ACIDS FOR 5DQF_A_LCRA612

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkp PHYTASE

(Escherichia
coli) 		PF00328
(His_Phos_2) 		5 LEU A 333
ASP A 304
LEU A 310
LEU A 271
ALA A 268
 None
IHP  A 550 (-3.2A)
None
None
None
 1.11A 5dqfA-1dkpA:
undetectable		 5dqfA-1dkpA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eov ASPARTYL-TRNA
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		5 LEU A 130
LEU A 140
GLY A 139
LEU A 128
ALA A 126
 None
 1.12A 5dqfA-1eovA:
undetectable		 5dqfA-1eovA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gey HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		5 LEU A  79
LEU A 235
LEU A 236
LEU A  91
ALA A  94
 None
 1.01A 5dqfA-1geyA:
undetectable		 5dqfA-1geyA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		5 LEU A 256
LEU A 248
GLY A 249
LEU A 262
LEU A 158
 None
 1.10A 5dqfA-1gqrA:
2.6		 5dqfA-1gqrA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvh FLAVOHEMOPROTEIN

(Escherichia
coli) 		PF00042
(Globin)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		5 LEU A 311
GLY A 312
LEU A 315
LEU A 281
ALA A 282
 None
 0.96A 5dqfA-1gvhA:
2.4		 5dqfA-1gvhA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltm 36 KDA SOLUBLE LYTIC
TRANSGLYCOSYLASE

(Escherichia
coli) 		PF13406
(SLT_2) 		5 LEU A  94
ASP A  89
LEU A  88
LEU A 181
ALA A 177
 None
 1.13A 5dqfA-1ltmA:
undetectable		 5dqfA-1ltmA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mus TN5 TRANSPOSASE

(Escherichia
coli) 		PF01609
(DDE_Tnp_1)
PF02281
(Dimer_Tnp_Tn5)
PF14706
(Tnp_DNA_bind) 		5 LEU A 309
LEU A 263
GLY A 236
LEU A 265
ALA A 284
 None
 0.92A 5dqfA-1musA:
undetectable		 5dqfA-1musA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oaa SEPIAPTERIN
REDUCTASE

(Mus musculus) 		PF00106
(adh_short) 		5 LEU A  13
GLY A  21
LEU A  24
LEU A 242
ALA A 239
 None
 1.06A 5dqfA-1oaaA:
undetectable		 5dqfA-1oaaA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1org PHEROMONE BINDING
PROTEIN

(Rhyparobia
maderae) 		PF01395
(PBP_GOBP) 		5 LEU A  31
LEU A  12
GLY A  10
LEU A  45
ALA A  48
 None
 1.06A 5dqfA-1orgA:
3.2		 5dqfA-1orgA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p22 SKP1

(Homo sapiens) 		PF01466
(Skp1)
PF03931
(Skp1_POZ) 		5 LEU B  95
GLY B  93
LEU B  94
LEU B  82
ALA B  86
 None
 1.05A 5dqfA-1p22B:
undetectable		 5dqfA-1p22B:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q15 CARA

(Pectobacterium
carotovorum) 		PF00733
(Asn_synthase)
PF09147
(DUF1933) 		5 LEU A  97
LEU A  87
LEU A  88
LEU A  65
ALA A  69
 None
 0.96A 5dqfA-1q15A:
undetectable		 5dqfA-1q15A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sk7 HYPOTHETICAL PROTEIN
PA-HO

(Pseudomonas
aeruginosa) 		PF01126
(Heme_oxygenase) 		5 LEU A  32
LEU A 192
GLY A 190
LEU A 193
ALA A  51
 None
 1.03A 5dqfA-1sk7A:
undetectable		 5dqfA-1sk7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 41 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08542
(Rep_fac_C) 		5 ASP D 227
LEU D 192
LEU D 221
LEU D 201
ALA D 197
 None
 0.95A 5dqfA-1sxjD:
4.6		 5dqfA-1sxjD:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		6 LYS A  20
LEU A  24
LEU A 135
LEU A 139
LEU A 155
ALA A 158
 None
 0.59A 5dqfA-1tf0A:
46.5		 5dqfA-1tf0A:
76.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		7 LYS A 212
ASP A 324
LEU A 327
GLY A 328
LEU A 331
LEU A 347
ALA A 350
 None
DKA  A1001 (-4.7A)
DKA  A1001 (-4.1A)
DKA  A1001 ( 4.1A)
None
DKA  A1002 ( 4.3A)
DKA  A1002 ( 3.8A)
 0.74A 5dqfA-1tf0A:
46.5		 5dqfA-1tf0A:
76.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcx UROPORPHYRINOGEN III
SYNTHASE

(Thermus
thermophilus) 		PF02602
(HEM4) 		5 LYS A  28
LEU A  29
LEU A 245
GLY A 246
LEU A 249
 None
 1.08A 5dqfA-1wcxA:
undetectable		 5dqfA-1wcxA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xpv HYPOTHETICAL PROTEIN
XCC2852

(Xanthomonas
campestris) 		PF05768
(DUF836) 		5 LEU A  59
ASP A  73
LEU A  68
LEU A  21
ALA A  24
 None
 1.08A 5dqfA-1xpvA:
undetectable		 5dqfA-1xpvA:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yix DEOXYRIBONUCLEASE
YCFH

(Escherichia
coli) 		PF01026
(TatD_DNase) 		5 LEU A 123
GLY A 120
LEU A  92
LEU A  80
ALA A  84
 None
 1.01A 5dqfA-1yixA:
undetectable		 5dqfA-1yixA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrm L-2-HALOACID
DEHALOGENASE

(Pseudomonas sp.
YL) 		PF13419
(HAD_2) 		5 LYS A   5
ASP A 167
GLY A 165
LEU A 164
ALA A 160
 None
 1.13A 5dqfA-1zrmA:
3.4		 5dqfA-1zrmA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ast S-PHASE
KINASE-ASSOCIATED
PROTEIN 1A

(Homo sapiens) 		PF01466
(Skp1)
PF03931
(Skp1_POZ) 		5 LEU A1116
GLY A1114
LEU A1115
LEU A1103
ALA A1107
 None
 1.05A 5dqfA-2astA:
undetectable		 5dqfA-2astA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c27 MYCOTHIOL SYNTHASE

(Mycobacterium
tuberculosis) 		PF00583
(Acetyltransf_1) 		5 LEU A 238
LEU A 249
GLY A 250
LEU A 253
ALA A 205
 COA  A1314 (-4.5A)
COA  A1314 (-4.9A)
COA  A1314 (-3.3A)
None
None
 0.99A 5dqfA-2c27A:
undetectable		 5dqfA-2c27A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu2 PUTATIVE
MANNOSE-1-PHOSPHATE
GUANYLYL TRANSFERASE

(Thermus
thermophilus) 		PF00483
(NTP_transferase) 		5 LEU A 103
LEU A  90
GLY A  91
LEU A   6
ALA A  57
 None
 1.09A 5dqfA-2cu2A:
undetectable		 5dqfA-2cu2A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eb0 MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Methanocaldococcus
jannaschii) 		PF01368
(DHH)
PF02833
(DHHA2) 		6 LEU A 167
ASP A 135
LEU A 139
GLY A 138
LEU A 140
ALA A  16
 None
 1.48A 5dqfA-2eb0A:
undetectable		 5dqfA-2eb0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3d HYPOTHETICAL PROTEIN
ATU1826

(Agrobacterium
fabrum) 		PF02129
(Peptidase_S15) 		5 LEU A  31
GLY A 114
LEU A 117
LEU A  89
ALA A  85
 None
 1.06A 5dqfA-2i3dA:
1.4		 5dqfA-2i3dA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibu ACETYL-COA
ACETYLTRANSFERASE

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		5 LEU A 402
LEU A 409
GLY A 408
LEU A 398
ALA A 410
 None
 1.07A 5dqfA-2ibuA:
undetectable		 5dqfA-2ibuA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2naf PEPTIDYL-TRNA
HYDROLASE

(Mycolicibacterium
smegmatis) 		PF01195
(Pept_tRNA_hydro) 		5 ASP A 171
LEU A 175
LEU A 176
LEU A 106
ALA A 184
 None
 1.10A 5dqfA-2nafA:
undetectable		 5dqfA-2nafA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 5 LEU A 490
LEU A 467
LEU A 471
LEU A 535
ALA A 534
 None
 1.13A 5dqfA-2po4A:
undetectable		 5dqfA-2po4A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r1i GCN5-RELATED
N-ACETYLTRANSFERASE

(Arthrobacter
sp. FB24) 		PF00583
(Acetyltransf_1) 		5 LEU A 102
LEU A 113
GLY A 114
LEU A 117
ALA A  74
 None
 0.84A 5dqfA-2r1iA:
undetectable		 5dqfA-2r1iA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uy3 ENDOCHITINASE

(Saccharomyces
cerevisiae) 		PF00704
(Glyco_hydro_18) 		5 LEU A 201
ASP A 207
LEU A 184
LEU A 200
ALA A 168
 None
 1.08A 5dqfA-2uy3A:
undetectable		 5dqfA-2uy3A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v3b RUBREDOXIN REDUCTASE

(Pseudomonas
aeruginosa) 		PF07992
(Pyr_redox_2) 		5 LEU A 265
LEU A 292
LEU A 275
LEU A  19
ALA A  15
 None
None
None
None
FAD  A1385 (-3.2A)
 1.07A 5dqfA-2v3bA:
undetectable		 5dqfA-2v3bA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3c GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Homo sapiens) 		PF04869
(Uso1_p115_head) 		5 LEU A 126
LEU A  65
LEU A  69
LEU A  83
ALA A  82
 None
 1.09A 5dqfA-2w3cA:
2.3		 5dqfA-2w3cA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6l COBE

(Pseudomonas
aeruginosa) 		PF01890
(CbiG_C) 		6 LEU A  84
LEU A 119
GLY A 120
LEU A 118
LEU A 105
ALA A 133
 None
 1.48A 5dqfA-2w6lA:
undetectable		 5dqfA-2w6lA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa7 ADAPTOR-RELATED
PROTEIN COMPLEX 2,
ALPHA 2 SUBUNIT

(Rattus
norvegicus) 		PF01602
(Adaptin_N) 		5 LEU A 334
GLY A 335
LEU A 338
LEU A 350
ALA A 349
 None
 0.93A 5dqfA-2xa7A:
undetectable		 5dqfA-2xa7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkx SAM-DEPENDENT
METHYLTRANSFERASE

(Lactobacillus
paracasei) 		PF13649
(Methyltransf_25) 		5 LEU A  94
LEU A  98
GLY A  99
LEU A 102
ALA A  61
 None
 1.13A 5dqfA-3bkxA:
undetectable		 5dqfA-3bkxA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3deo SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN

(Arabidopsis
thaliana) 		PF12796
(Ank_2) 		5 LEU A 179
ASP A 173
LEU A 164
LEU A 186
ALA A 197
 None
 1.00A 5dqfA-3deoA:
undetectable		 5dqfA-3deoA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dez OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Streptococcus
mutans) 		PF00156
(Pribosyltran) 		5 LYS A 184
ASP A 192
LEU A 196
LEU A 197
LEU A  19
 None
 1.10A 5dqfA-3dezA:
undetectable		 5dqfA-3dezA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm5 SIGNAL RECOGNITION
54 KDA PROTEIN

(Pyrococcus
furiosus) 		PF00448
(SRP54)
PF02881
(SRP54_N)
PF02978
(SRP_SPB) 		5 ASP A   4
GLY A   7
LEU A  10
LEU A  39
ALA A  38
 None
 0.89A 5dqfA-3dm5A:
4.1		 5dqfA-3dm5A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwb ENDOTHELIN-CONVERTIN
G ENZYME 1

(Homo sapiens) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		5 LEU A 443
GLY A 444
LEU A 447
LEU A 164
ALA A 178
 None
 0.90A 5dqfA-3dwbA:
undetectable		 5dqfA-3dwbA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqa GLUCOAMYLASE

(Aspergillus
niger) 		PF00723
(Glyco_hydro_15) 		5 LEU A 201
LEU A 273
LEU A 274
LEU A 343
ALA A 347
 None
 1.00A 5dqfA-3eqaA:
undetectable		 5dqfA-3eqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fs4 HEMOGLOBIN SUBUNIT
BETA

(Struthio
camelus) 		PF00042
(Globin) 		5 LEU B 106
GLY B 107
LEU B 110
LEU B  68
ALA B  27
 HEM  B 150 (-4.5A)
None
None
None
None
 1.10A 5dqfA-3fs4B:
1.8		 5dqfA-3fs4B:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Bos taurus) 		PF04869
(Uso1_p115_head) 		5 LEU A 126
LEU A  65
LEU A  69
LEU A  83
ALA A  82
 None
 0.99A 5dqfA-3gq2A:
undetectable		 5dqfA-3gq2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsi N,N-DIMETHYLGLYCINE
OXIDASE

(Arthrobacter
globiformis) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		5 LYS A 103
LEU A 102
LEU A 119
GLY A 139
LEU A 140
 None
 1.13A 5dqfA-3gsiA:
undetectable		 5dqfA-3gsiA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB4
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB7

(Schizosaccharomyces
pombe) 		PF00575
(S1)
PF03874
(RNA_pol_Rpb4)
PF03876
(SHS2_Rpb7-N) 		5 ASP D  23
LEU G   5
LEU G  79
LEU G   8
ALA G  77
 None
 0.99A 5dqfA-3h0gD:
undetectable		 5dqfA-3h0gD:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdn SERINE/THREONINE-PRO
TEIN KINASE SGK1

(Homo sapiens) 		PF00069
(Pkinase) 		5 LEU A 328
LEU A 283
GLY A 284
LEU A 287
ALA A 203
 None
 1.04A 5dqfA-3hdnA:
undetectable		 5dqfA-3hdnA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjr EXTRACELLULAR SERINE
PROTEASE

(Aeromonas
sobria) 		PF00082
(Peptidase_S8)
PF01483
(P_proprotein) 		5 LEU A  68
GLY A  69
LEU A 348
LEU A  59
ALA A  62
 None
 1.12A 5dqfA-3hjrA:
undetectable		 5dqfA-3hjrA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2n WD REPEAT-CONTAINING
PROTEIN 92

(Homo sapiens) 		PF00400
(WD40) 		5 ASP A 191
GLY A 186
LEU A 215
LEU A 227
ALA A 229
 None
 1.09A 5dqfA-3i2nA:
undetectable		 5dqfA-3i2nA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iqt SIGNAL TRANSDUCTION
HISTIDINE-PROTEIN
KINASE BARA

(Escherichia
coli) 		PF01627
(Hpt) 		5 LEU A 848
ASP A 894
LEU A 895
LEU A 899
LEU A 856
 None
 1.13A 5dqfA-3iqtA:
2.4		 5dqfA-3iqtA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kt4 PKHD-TYPE
HYDROXYLASE TPA1

(Saccharomyces
cerevisiae) 		PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4) 		5 ASP A 374
LEU A 378
LEU A 379
LEU A 474
ALA A 470
 None
 1.10A 5dqfA-3kt4A:
undetectable		 5dqfA-3kt4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lfu DNA HELICASE II

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		5 LEU A 444
ASP A 424
LEU A 450
LEU A 458
ALA A 454
 None
 1.08A 5dqfA-3lfuA:
undetectable		 5dqfA-3lfuA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6f HYPOTHETICAL
ACETYLTRANSFERASE

(Deinococcus
radiodurans) 		PF13673
(Acetyltransf_10) 		5 LEU A  78
LEU A  89
GLY A  90
LEU A  93
ALA A  52
 LEU  A  78 (-0.5A)
LEU  A  89 (-0.5A)
GLY  A  90 (-0.0A)
LEU  A  93 ( 0.6A)
ALA  A  52 ( 0.0A)
 0.96A 5dqfA-3s6fA:
undetectable		 5dqfA-3s6fA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ui2 SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF12796
(Ank_2) 		5 LEU A 179
ASP A 173
LEU A 164
LEU A 186
ALA A 197
 None
 1.10A 5dqfA-3ui2A:
3.1		 5dqfA-3ui2A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vh1 UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7

(Saccharomyces
cerevisiae) 		PF00899
(ThiF)
PF16420
(ATG7_N) 		5 LEU A 462
GLY A 463
LEU A 503
LEU A 468
ALA A 461
 None
 1.13A 5dqfA-3vh1A:
undetectable		 5dqfA-3vh1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2n 70 KDA PROTEIN

(Xanthomonas sp.
35Y) 		no annotation 5 ASP A 217
GLY A 142
LEU A 143
LEU A 173
ALA A 193
 None
None
None
None
HEM  A 700 ( 4.9A)
 1.08A 5dqfA-4b2nA:
undetectable		 5dqfA-4b2nA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd4 ARYLALKYLAMINE
N-ACETYLTRANSFERASE
LIKE 5B

(Aedes aegypti) 		PF00583
(Acetyltransf_1) 		5 LEU A 132
LEU A 143
GLY A 144
LEU A 147
ALA A  64
 None
 0.86A 5dqfA-4fd4A:
undetectable		 5dqfA-4fd4A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ikv DI-TRIPEPTIDE ABC
TRANSPORTER
(PERMEASE)

(Geobacillus
kaustophilus) 		PF00854
(PTR2) 		5 LEU A 375
GLY A 478
LEU A 481
LEU A 298
ALA A 301
 None
 1.12A 5dqfA-4ikvA:
undetectable		 5dqfA-4ikvA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kzk L-ARABINOSE ABC
TRANSPORTER,
PERIPLASMIC
L-ARABINOSE-BINDING
PROTEIN

(Burkholderia
thailandensis) 		PF00532
(Peripla_BP_1) 		5 LEU A 130
LEU A 100
GLY A 101
LEU A 122
ALA A  95
 None
 0.98A 5dqfA-4kzkA:
undetectable		 5dqfA-4kzkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0d N-ACETYLMURAMIC ACID
6-PHOSPHATE ETHERASE

(Haemophilus
influenzae) 		PF01380
(SIS) 		5 LEU A 272
LEU A 289
LEU A 290
LEU A 297
ALA A 300
 None
 1.03A 5dqfA-4m0dA:
undetectable		 5dqfA-4m0dA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mph D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF02557
(VanY) 		5 LEU A 164
GLY A 163
LEU A  98
LEU A 106
ALA A 102
 None
 1.01A 5dqfA-4mphA:
undetectable		 5dqfA-4mphA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nee AP-2 COMPLEX SUBUNIT
ALPHA-2

(Rattus
norvegicus) 		no annotation 5 LEU G 334
GLY G 335
LEU G 338
LEU G 350
ALA G 349
 None
 0.88A 5dqfA-4neeG:
undetectable		 5dqfA-4neeG:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nv2 VKORC1/THIOREDOXIN
DOMAIN PROTEIN

(Synechococcus
sp.
JA-2-3B'a(2-13)) 		PF07884
(VKOR) 		5 LEU A 107
LEU A  84
GLY A  82
LEU A  23
ALA A  27
 None
 0.98A 5dqfA-4nv2A:
2.7		 5dqfA-4nv2A:
21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		5 LEU A  24
GLY A 136
LEU A 139
LEU A 155
ALA A 158
 None
 0.47A 5dqfA-4po0A:
50.0		 5dqfA-4po0A:
71.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		6 LYS A 212
ASP A 324
LEU A 327
GLY A 328
LEU A 331
LEU A 347
 None
NPS  A 602 ( 4.4A)
NPS  A 602 ( 4.7A)
NPS  A 602 (-3.8A)
None
NPS  A 602 ( 4.2A)
 0.91A 5dqfA-4po0A:
50.0		 5dqfA-4po0A:
71.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		6 LYS A 212
LEU A 216
LEU A 327
GLY A 328
LEU A 331
LEU A 347
 None
NPS  A 602 ( 4.8A)
NPS  A 602 ( 4.7A)
NPS  A 602 (-3.8A)
None
NPS  A 602 ( 4.2A)
 0.73A 5dqfA-4po0A:
50.0		 5dqfA-4po0A:
71.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywr PUTATIVE
HYDROXYMETHYLPYRIMID
INE
KINASE/PHOSPHOMETHYL
PYRIMIDINE KINASE

(Acinetobacter
baumannii) 		PF08543
(Phos_pyr_kin) 		5 LYS A  84
LEU A 111
LEU A 136
LEU A 101
ALA A  98
 PLP  A 300 ( 4.3A)
None
None
None
None
 1.04A 5dqfA-4ywrA:
undetectable		 5dqfA-4ywrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3k SEPIAPTERIN
REDUCTASE

(Homo sapiens) 		PF00106
(adh_short) 		5 LEU A   9
GLY A  17
LEU A  20
LEU A 238
ALA A 235
 None
 1.02A 5dqfA-4z3kA:
undetectable		 5dqfA-4z3kA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bz3 NA(+)/H(+)
ANTIPORTER

(Thermus
thermophilus) 		PF00999
(Na_H_Exchanger) 		6 LEU A 248
LEU A 243
GLY A 244
LEU A 247
LEU A 198
ALA A 195
 None
 1.44A 5dqfA-5bz3A:
undetectable		 5dqfA-5bz3A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d68 KREV INTERACTION
TRAPPED PROTEIN 1

(Homo sapiens) 		PF00373
(FERM_M)
PF13857
(Ank_5) 		5 LEU A 374
ASP A 381
LEU A 375
LEU A 411
ALA A 414
 None
 1.01A 5dqfA-5d68A:
undetectable		 5dqfA-5d68A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2g BETA-LACTAMASE

(Burkholderia
cenocepacia) 		PF00144
(Beta-lactamase) 		5 LEU A 104
ASP A  82
LEU A 153
LEU A 264
ALA A  69
 None
 0.95A 5dqfA-5e2gA:
undetectable		 5dqfA-5e2gA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2h BETA-LACTAMASE

(Mycolicibacterium
smegmatis) 		PF00144
(Beta-lactamase) 		5 LEU A 103
ASP A  81
LEU A 152
LEU A 263
ALA A  68
 None
 0.80A 5dqfA-5e2hA:
undetectable		 5dqfA-5e2hA:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		6 ASP A 324
LEU A 327
GLY A 328
LEU A 331
LEU A 347
ALA A 350
 None
 0.42A 5dqfA-5ghkA:
47.3		 5dqfA-5ghkA:
76.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		6 LEU A  24
LEU A 135
GLY A 136
LEU A 139
LEU A 155
ALA A 158
 None
 0.29A 5dqfA-5ghkA:
47.3		 5dqfA-5ghkA:
76.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghs SSDNA-SPECIFIC
EXONUCLEASE

(Thermococcus
kodakarensis) 		PF02272
(DHHA1) 		5 LEU A 302
LEU A 313
GLY A 314
LEU A 332
ALA A 328
 None
 0.95A 5dqfA-5ghsA:
undetectable		 5dqfA-5ghsA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl6 RIBOSOME MATURATION
FACTOR RIMP

(Mycolicibacterium
smegmatis) 		PF02576
(DUF150)
PF17384
(DUF150_C) 		5 ASP A  55
GLY A  57
LEU A  58
LEU A  66
ALA A  62
 None
 1.12A 5dqfA-5gl6A:
undetectable		 5dqfA-5gl6A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2v IMPORTIN SUBUNIT
BETA-3

(Saccharomyces
cerevisiae) 		PF13513
(HEAT_EZ) 		5 LEU A 538
LEU A 498
LEU A 502
LEU A 514
ALA A 513
 None
 0.91A 5dqfA-5h2vA:
undetectable		 5dqfA-5h2vA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ica PERIODIC TRYPTOPHAN
PROTEIN 2-LIKE
PROTEIN
PUTATIVE U3 SNORNP
PROTEIN

(Chaetomium
thermophilum) 		PF04003
(Utp12)
PF04192
(Utp21) 		5 LEU C1044
ASP D 799
GLY D 802
LEU D 805
LEU D 774
 None
 1.05A 5dqfA-5icaC:
undetectable		 5dqfA-5icaC:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8r PROTOCADHERIN
GAMMA-B3

(Homo sapiens) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		5 LEU A 117
GLY A 119
LEU A 166
LEU A 170
ALA A 116
 None
 1.10A 5dqfA-5k8rA:
undetectable		 5dqfA-5k8rA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kx6 GALACTOSIDE
2-ALPHA-L-FUCOSYLTRA
NSFERASE

(Arabidopsis
thaliana) 		PF03254
(XG_FTase) 		5 LEU A 491
LEU A 331
GLY A 332
LEU A 187
ALA A 190
 None
 0.98A 5dqfA-5kx6A:
undetectable		 5dqfA-5kx6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m09 SERINE/THREONINE-PRO
TEIN KINASE PKNI

(Mycobacterium
tuberculosis) 		PF00069
(Pkinase) 		5 ASP A 226
LEU A 229
LEU A 233
LEU A 190
ALA A 189
 None
 0.91A 5dqfA-5m09A:
undetectable		 5dqfA-5m09A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		5 ASP A1506
GLY A1541
LEU A1398
LEU A1546
ALA A1400
 None
 1.11A 5dqfA-5m59A:
2.9		 5dqfA-5m59A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA

(Nostoc sp. PCC
7120) 		no annotation 5 LYS A 126
LEU A 127
LEU A 112
LEU A 155
ALA A 154
 None
 1.09A 5dqfA-5n3uA:
undetectable		 5dqfA-5n3uA:
10.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 6 ASP A 323
LEU A 326
GLY A 327
LEU A 330
LEU A 346
ALA A 349
 None
 0.56A 5dqfA-5oriA:
50.6		 5dqfA-5oriA:
75.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 5 LEU A  24
GLY A 135
LEU A 138
LEU A 154
ALA A 157
 None
 0.33A 5dqfA-5oriA:
50.6		 5dqfA-5oriA:
75.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tos SERINE/THREONINE-PRO
TEIN KINASE BIK1

(Arabidopsis
thaliana) 		no annotation 5 LEU A 290
LEU A 269
LEU A 270
LEU A 332
ALA A 328
 None
 1.06A 5dqfA-5tosA:
undetectable		 5dqfA-5tosA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr PROTEASOME SUBUNIT
ALPHA TYPE-4

(Homo sapiens) 		no annotation 5 LEU I  45
GLY I  36
LEU I  44
LEU I 190
ALA I 189
 None
 1.09A 5dqfA-5vfrI:
2.1		 5dqfA-5vfrI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE

(Tribolium
castaneum) 		no annotation 5 LEU A  71
GLY A  72
LEU A  75
LEU A 101
ALA A 100
 None
 1.05A 5dqfA-5vg9A:
undetectable		 5dqfA-5vg9A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xm3 GLUCOSE
DEHYDROGENASE

(Methylophaga
aminisulfidivorans) 		no annotation 5 ASP A 524
LEU A 523
GLY A 546
LEU A 576
ALA A 573
 None
 1.06A 5dqfA-5xm3A:
undetectable		 5dqfA-5xm3A:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnz CRED

(Streptomyces
cremeus) 		no annotation 5 LEU A 435
GLY A 374
LEU A 412
LEU A 398
ALA A 402
 None
 1.10A 5dqfA-5xnzA:
undetectable		 5dqfA-5xnzA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xww AMPHB

(Streptomyces
nodosus) 		no annotation 5 LEU A 176
ASP A  43
LEU A  42
LEU A  24
ALA A  26
 None
 1.03A 5dqfA-5xwwA:
undetectable		 5dqfA-5xwwA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxs PROTEIN RIBT

(Bacillus
subtilis) 		no annotation 5 LEU A  29
LEU A  16
LEU A  17
LEU A  44
ALA A  56
 None
 1.13A 5dqfA-5xxsA:
undetectable		 5dqfA-5xxsA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 6 LEU A  24
LEU A 135
GLY A 136
LEU A 139
LEU A 155
ALA A 158
 None
 0.37A 5dqfA-5yxeA:
45.6		 5dqfA-5yxeA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 7 LYS A 212
ASP A 324
LEU A 327
GLY A 328
LEU A 331
LEU A 347
ALA A 350
 None
 0.68A 5dqfA-5yxeA:
45.6		 5dqfA-5yxeA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE

(Pseudomonas
aeruginosa) 		no annotation 5 LEU A 135
GLY A 168
LEU A 174
LEU A 178
ALA A 177
 None
 1.03A 5dqfA-5zbkA:
undetectable		 5dqfA-5zbkA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT E

(Flavobacterium
johnsoniae) 		no annotation 5 ASP E 172
LEU E 169
GLY E 100
LEU E 103
LEU E 162
 None
 0.97A 5dqfA-6btmE:
2.2		 5dqfA-6btmE:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4m YERSINOPINE
DEHYDROGENASE

(Yersinia pestis) 		no annotation 5 ASP C  74
LEU C  31
GLY C  32
LEU C  54
ALA C  20
 None
 0.99A 5dqfA-6c4mC:
undetectable		 5dqfA-6c4mC:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emk SERINE/THREONINE-PRO
TEIN KINASE TOR2

(Saccharomyces
cerevisiae) 		no annotation 5 ASP A2299
LEU A2275
GLY A2274
LEU A2273
LEU A2140
 None
 1.07A 5dqfA-6emkA:
undetectable		 5dqfA-6emkA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3d INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 4

(Homo sapiens) 		no annotation 5 LEU A 396
LEU A 377
LEU A 378
LEU A 437
ALA A 433
 None
 1.03A 5dqfA-6f3dA:
undetectable		 5dqfA-6f3dA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG

(Homo sapiens) 		no annotation 5 LEU C 615
ASP C 519
LEU C 522
LEU C 526
LEU C 672
 None
 0.88A 5dqfA-6f7sC:
undetectable		 5dqfA-6f7sC:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6frv GLUCOAMYLASE

(Aspergillus
niger) 		no annotation 5 LEU A 201
LEU A 273
LEU A 274
LEU A 343
ALA A 347
 None
 0.99A 5dqfA-6frvA:
undetectable		 5dqfA-6frvA:
10.52